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Fusion gene ID: 6209 |
FusionGeneSummary for CD58_RAD51B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CD58_RAD51B | Fusion gene ID: 6209 | Hgene | Tgene | Gene symbol | CD58 | RAD51B | Gene ID | 965 | 5890 |
| Gene name | CD58 molecule | RAD51 paralog B | |
| Synonyms | LFA-3|LFA3|ag3 | R51H2|RAD51L1|REC2 | |
| Cytomap | 1p13.1 | 14q24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lymphocyte function-associated antigen 3CD58 antigen, (lymphocyte function-associated antigen 3)surface glycoprotein LFA-3 | DNA repair protein RAD51 homolog 2RAD51 homolog BRecA-like proteinrecombination repair protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P19256 | O15315 | |
| Ensembl transtripts involved in fusion gene | ENST00000369489, ENST00000457047, ENST00000369487, | ENST00000487861, ENST00000471583, ENST00000487270, ENST00000488612, ENST00000390683, ENST00000469165, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 25 X 15 X 8=3000 |
| # samples | 2 | 33 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(33/3000*10)=-3.18442457113743 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CD58 [Title/Abstract] AND RAD51B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CD58 | GO:0034113 | heterotypic cell-cell adhesion | 15345303 |
| Hgene | CD58 | GO:0071346 | cellular response to interferon-gamma | 19109405 |
| Hgene | CD58 | GO:0071356 | cellular response to tumor necrosis factor | 19109405 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-B6-A400-01A | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000369489 | ENST00000487861 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369489 | ENST00000471583 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369489 | ENST00000487270 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369489 | ENST00000488612 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369489 | ENST00000390683 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| 5CDS-3UTR | ENST00000369489 | ENST00000469165 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000457047 | ENST00000487861 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000457047 | ENST00000471583 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000457047 | ENST00000487270 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000457047 | ENST00000488612 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000457047 | ENST00000390683 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| 5CDS-3UTR | ENST00000457047 | ENST00000469165 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369487 | ENST00000487861 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369487 | ENST00000471583 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369487 | ENST00000487270 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369487 | ENST00000488612 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| In-frame | ENST00000369487 | ENST00000390683 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
| 5CDS-3UTR | ENST00000369487 | ENST00000469165 | CD58 | chr1 | 117113525 | - | RAD51B | chr14 | 68758601 | + |
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FusionProtFeatures for CD58_RAD51B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CD58 | RAD51B |
| Ligand of the T-lymphocyte CD2 glycoprotein. Thisinteraction is important in mediating thymocyte interactions withthymic epithelial cells, antigen-independent and -dependentinteractions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes.In addition, the LFA-3/CD2 interaction may prime response by boththe CD2+ and LFA-3+ cells. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000369489 | - | 1 | 6 | 30_121 | 23 | 251 | Domain | Note=Ig-like |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000457047 | - | 1 | 5 | 30_121 | 23 | 249 | Domain | Note=Ig-like |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000369489 | - | 1 | 6 | 239_250 | 23 | 251 | Topological domain | Cytoplasmic |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000369489 | - | 1 | 6 | 29_215 | 23 | 251 | Topological domain | Extracellular |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000457047 | - | 1 | 5 | 239_250 | 23 | 249 | Topological domain | Cytoplasmic |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000457047 | - | 1 | 5 | 29_215 | 23 | 249 | Topological domain | Extracellular |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000369489 | - | 1 | 6 | 216_238 | 23 | 251 | Transmembrane | Helical |
| Hgene | >CD58 | chr1:117113525 | chr14:68758601 | ENST00000457047 | - | 1 | 5 | 216_238 | 23 | 249 | Transmembrane | Helical |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000390683 | + | 5 | 10 | 108_115 | 252 | 367 | Nucleotide binding | ATP |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000471583 | + | 6 | 11 | 108_115 | 252 | 351 | Nucleotide binding | ATP |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000487270 | + | 6 | 11 | 108_115 | 252 | 385 | Nucleotide binding | ATP |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000488612 | + | 6 | 12 | 108_115 | 252 | 495 | Nucleotide binding | ATP |
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FusionGeneSequence for CD58_RAD51B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_197aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT DSYCQVPSGSLHLICLHHQGGRPGSSSCXNCGQSQPQVRMLVSSRLTSQPYLPDTXCGAQKNKESQAVTQCLHVPSTDALNCPLFCSSSY >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_122aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_156aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_197aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT DSYCQVPSGSLHLICLHHQGGRPGSSSCXNCGQSQPQVRMLVSSRLTSQPYLPDTXCGAQKNKESQAVTQCLHVPSTDALNCPLFCSSSY >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_122aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_156aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_197aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT DSYCQVPSGSLHLICLHHQGGRPGSSSCXNCGQSQPQVRMLVSSRLTSQPYLPDTXCGAQKNKESQAVTQCLHVPSTDALNCPLFCSSSY >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_122aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_156aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_138aa MVAGSDAGRALGVLSVVCLLHCFGYLDESDYNPSEWSPGFSGRPGVSSXXFVPVXRHFWIQLCDSRTRKYLESQCEYPADPPVPXFREKT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_592nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAAC TGTGGCCAGAGTCAGCCCCAGGTCAGAATGCTGGTCAGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAG AAAAACAAGGAATCCCAGGCTGTTACCCAGTGTCTCCATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTAC >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_367nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAA >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_469nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATT TTGCTCTGTCACCCAAGCTGAACTGAACTGGGCTCCAGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCA >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_592nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAAC TGTGGCCAGAGTCAGCCCCAGGTCAGAATGCTGGTCAGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAG AAAAACAAGGAATCCCAGGCTGTTACCCAGTGTCTCCATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTAC >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_367nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_469nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATT TTGCTCTGTCACCCAAGCTGAACTGAACTGGGCTCCAGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_592nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAAC TGTGGCCAGAGTCAGCCCCAGGTCAGAATGCTGGTCAGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAG AAAAACAAGGAATCCCAGGCTGTTACCCAGTGTCTCCATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTAC >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_367nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAA >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_469nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATT TTGCTCTGTCACCCAAGCTGAACTGAACTGGGCTCCAGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCA >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_415nt ATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGAT TACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATC CAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACA GATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_977nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAACTGTGGCCAGAGTCAGCCCCAGGT CAGAATGCTGGTCAGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAGAAAAACAAGGAATCCCAGGCTGT TACCCAGTGTCTCCATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTACAAACTGGGCAACTGGAATCAGAA CAGAGACTTTGGATGAGCATCCAGTGTAACCCAGCCTAGTTTTTCACCACGACTTCCAGATCTACATTTAACATCCGACAGCAACTATAA TTCTACTTTCTGAACCTCCAGGGAAGTTGCTTCCTTGTCCCTTTCAGCAAAGGATGTCATGGTTTTACAATGTCTCCAGTGAAAAAGTTC TTCTTCTCTACATCTTCCTCCCACTCCTACAACCCTTGATCCCCACGTGAGATCTCATTTCCTCCAGCTGGGTCTTCTGCAGAGTGATTA >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_869nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAAGCCATAGGGATACTGTGACCTTT GTCTAGAGTTGATGGGGGTGTGATTTGTGAAATAAAACAGGACCGTACTGCTTGGAAGAAGGAAACGGAAGCTGACATAATGGGGATTAA TTAGTTGATTGCTGTTGAGATGGTAACAGATTTGCTCCTAAACCATTGAGCTAGCGATTTCAGACCTAGCAGGGAAGGTGAAGATGAAGA AGCCTTTGTTCAGGTCTCTAGATGTGTAGGGCTGAGGGCTTTGCCGCCATGGGATGTCAACAGCCATAATAATAATTTGCACTTATATAG CACCTTTCAACCAGGCACCTCAAAGCGGTTTAACCACATTAATTAATTAAAGCCCACAATCCTCCTGGGGAGAGGAGGAGGATGACTAAC >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_1929nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATTTTGCTCTGTCACCCAAGCTGAAC TGAACTGGGCTCCAGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCATACCCAGCTAATTTTTTAATTTT TTGTAGAGGTGGGGTCTCATTATGTTGCCCAAGCTGATCTCAAACTCCTGGCTTCAAGAGATCCACCCACCTCAGCCTCCCAAAGCGCTA GGATTACAAGTATGAGACTTTGCCATTCCAATGAGAATTTTGTCCTTAGCAATCTCATCCAATGGCCACTGGAGATGTGTGTAGGGCCAC AAGAATGAGAAAGGGGGCAATGGAGTGACAGGTGACCTGCTCAGGTGCCCCTCCCCAGACCAAATGTCCCAGGCACACAGCCCATGCCCT CCACCATGGAGTACATTTTCTCCCTGGCTTGCTGCTGAGCTAAAGGACCAGGGACGTGGAAACAGGAGGTGAACTAAGGCACCCCGCCAC CCACTGTGGCAGCTTGAATTTCTTGAGGCTGAGACAAACTAGGATCCAGTAGCCTAGATTTTGCCCCAGTTTCTCCACTGAGTATTTACT CAGTGCTCCTGAGCCGATGCCTTCCCCTCTGCCTAGATGAACCACAGCATTTTGGTAAATGCCTCAGCATGTTAGGAGCGCTGGAACGTT TATTCTCTTCCCTCCCAATTATCCACTCTAATGGAGCAGAACACTTACATGGAAAATCCTAAACATGGAAGATGATTTAAAAATGATTCA CCCTGGAATACATGCTTCCAGTTGCTTCTACAGGTTTACCTTGCTAAAGGCATTTCGCTTCCTTTGCTGTTACAATAAGCTTGCCTGCCT TGAAGAAAAGAAGACCAGGGCCAAAGGGAAATCAGTCAAGGGAGCCTGTTTTGTCTGAAATAATGCATCCATGAACAAATGAATTGAGTA TAACTGTCTTTTTACATCAGTGTTTCTGTGGAATTAAGAGAACATCCAAGGCCACTCCTAGCTTGAGTAGATTAAATTTGTCCTTGTGTT TGGAGCAAGGGTTGTGAAGTCTGTCTGGCCCATCAAATGACCAATGGCTTTTAAGGAAGGACTAAGTGACTTATGACCAGAACAAGGGAG CAGCCTGAGTCAGTCTCCCCAATGTCTACATTGTGTTATTTATACTAGCAAAAAAATAGACACAACTAAATGTTCGACCATATGGTATTG GTTAAATTAACATCTATACGATGGAATACTAGATGGTCATTAAAATTATGTGTCAGAAGAAGGCTTAATCTCATGGGAAAGTGTTCACAC CATATTATTAAAGAGAAAAAACAGATTATAAAGCAATATGCATACAATGTAGTAGTTCTGTAAGAAAAAAGTATTATGTGCATTTTAACT GGAAAAATATGTATAAAAATGTTAACAGTGCAATCTCTGGGCAATAAGATTATACTTGACTTTTATTTCTTTTTTGGAATTGTCTTTTTT >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_904nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAA TCCAGAACAGACTAAAAGAAAATGAGTCCTGAGATTGCTACAGATGAGACCCACCCATCGGAGCCAGGCTTTGAAGGAACTGACCGCAGT GTGCATGAGGAAGTACTTCACGGTGATGACCCTCGCCACCCTCTCAGGAAAACACAGTGACCTCTCCCCCAACATCCCCTTCCCACTCCC AGGTCCCCCGGCAAAGGCAGAAGAACCAAGCAAGCCTTTCCACCAAAGCAGCCATGAACCCCATTCTCATCCTTTCCAAGAACTCTCTGC TATACCAGATAGGGGTTTGGGGTTCTGTTTTCCATTTTTTAAAAAAATCATTTCAAGACTCTTGAACAGTGTGTCGGTTTACACTATTCT ATCTTCTTAAGCCACCATATCAACATATTCACTCTGCTTCCTTTCTTTTCATTTGGCAGATGCCACACTTTTAATGGCAGCAATAAAAGG >In-frame_CD58_ENST00000369489_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_482nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_964nt GAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGG GTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGC AGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAG TCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCAC CTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAACTGTGGCCAGAGTCAGCCCCAGGTCAGAATGCTGGTC AGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAGAAAAACAAGGAATCCCAGGCTGTTACCCAGTGTCTC CATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTACAAACTGGGCAACTGGAATCAGAACAGAGACTTTGGA TGAGCATCCAGTGTAACCCAGCCTAGTTTTTCACCACGACTTCCAGATCTACATTTAACATCCGACAGCAACTATAATTCTACTTTCTGA ACCTCCAGGGAAGTTGCTTCCTTGTCCCTTTCAGCAAAGGATGTCATGGTTTTACAATGTCTCCAGTGAAAAAGTTCTTCTTCTCTACAT CTTCCTCCCACTCCTACAACCCTTGATCCCCACGTGAGATCTCATTTCCTCCAGCTGGGTCTTCTGCAGAGTGATTAGAGCTTCTGCCCT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_856nt GAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGG GTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGC AGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAG TCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCAC CTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAAGCCATAGGGATACTGTGACCTTTGTCTAGAGTTGAT GGGGGTGTGATTTGTGAAATAAAACAGGACCGTACTGCTTGGAAGAAGGAAACGGAAGCTGACATAATGGGGATTAATTAGTTGATTGCT GTTGAGATGGTAACAGATTTGCTCCTAAACCATTGAGCTAGCGATTTCAGACCTAGCAGGGAAGGTGAAGATGAAGAAGCCTTTGTTCAG GTCTCTAGATGTGTAGGGCTGAGGGCTTTGCCGCCATGGGATGTCAACAGCCATAATAATAATTTGCACTTATATAGCACCTTTCAACCA GGCACCTCAAAGCGGTTTAACCACATTAATTAATTAAAGCCCACAATCCTCCTGGGGAGAGGAGGAGGATGACTAACAAGATTTGTAATT >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_1916nt GAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGG GTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGC AGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAG TCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCAC CTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATTTTGCTCTGTCACCCAAGCTGAACTGAACTGGGCTCC AGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCATACCCAGCTAATTTTTTAATTTTTTGTAGAGGTGGG GTCTCATTATGTTGCCCAAGCTGATCTCAAACTCCTGGCTTCAAGAGATCCACCCACCTCAGCCTCCCAAAGCGCTAGGATTACAAGTAT GAGACTTTGCCATTCCAATGAGAATTTTGTCCTTAGCAATCTCATCCAATGGCCACTGGAGATGTGTGTAGGGCCACAAGAATGAGAAAG GGGGCAATGGAGTGACAGGTGACCTGCTCAGGTGCCCCTCCCCAGACCAAATGTCCCAGGCACACAGCCCATGCCCTCCACCATGGAGTA CATTTTCTCCCTGGCTTGCTGCTGAGCTAAAGGACCAGGGACGTGGAAACAGGAGGTGAACTAAGGCACCCCGCCACCCACTGTGGCAGC TTGAATTTCTTGAGGCTGAGACAAACTAGGATCCAGTAGCCTAGATTTTGCCCCAGTTTCTCCACTGAGTATTTACTCAGTGCTCCTGAG CCGATGCCTTCCCCTCTGCCTAGATGAACCACAGCATTTTGGTAAATGCCTCAGCATGTTAGGAGCGCTGGAACGTTTATTCTCTTCCCT CCCAATTATCCACTCTAATGGAGCAGAACACTTACATGGAAAATCCTAAACATGGAAGATGATTTAAAAATGATTCACCCTGGAATACAT GCTTCCAGTTGCTTCTACAGGTTTACCTTGCTAAAGGCATTTCGCTTCCTTTGCTGTTACAATAAGCTTGCCTGCCTTGAAGAAAAGAAG ACCAGGGCCAAAGGGAAATCAGTCAAGGGAGCCTGTTTTGTCTGAAATAATGCATCCATGAACAAATGAATTGAGTATAACTGTCTTTTT ACATCAGTGTTTCTGTGGAATTAAGAGAACATCCAAGGCCACTCCTAGCTTGAGTAGATTAAATTTGTCCTTGTGTTTGGAGCAAGGGTT GTGAAGTCTGTCTGGCCCATCAAATGACCAATGGCTTTTAAGGAAGGACTAAGTGACTTATGACCAGAACAAGGGAGCAGCCTGAGTCAG TCTCCCCAATGTCTACATTGTGTTATTTATACTAGCAAAAAAATAGACACAACTAAATGTTCGACCATATGGTATTGGTTAAATTAACAT CTATACGATGGAATACTAGATGGTCATTAAAATTATGTGTCAGAAGAAGGCTTAATCTCATGGGAAAGTGTTCACACCATATTATTAAAG AGAAAAAACAGATTATAAAGCAATATGCATACAATGTAGTAGTTCTGTAAGAAAAAAGTATTATGTGCATTTTAACTGGAAAAATATGTA TAAAAATGTTAACAGTGCAATCTCTGGGCAATAAGATTATACTTGACTTTTATTTCTTTTTTGGAATTGTCTTTTTTTTTTTTTTTTCAA >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_891nt GAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGG GTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGC AGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAG TCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCAC CTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAATCCAGAACAGACT AAAAGAAAATGAGTCCTGAGATTGCTACAGATGAGACCCACCCATCGGAGCCAGGCTTTGAAGGAACTGACCGCAGTGTGCATGAGGAAG TACTTCACGGTGATGACCCTCGCCACCCTCTCAGGAAAACACAGTGACCTCTCCCCCAACATCCCCTTCCCACTCCCAGGTCCCCCGGCA AAGGCAGAAGAACCAAGCAAGCCTTTCCACCAAAGCAGCCATGAACCCCATTCTCATCCTTTCCAAGAACTCTCTGCTATACCAGATAGG GGTTTGGGGTTCTGTTTTCCATTTTTTAAAAAAATCATTTCAAGACTCTTGAACAGTGTGTCGGTTTACACTATTCTATCTTCTTAAGCC >In-frame_CD58_ENST00000457047_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_469nt GAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGGGCGGGCCCTGGGG GTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCCTGGCTTCTCAGGC AGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAGGAAATACCTGGAG TCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTCTGGCTCCCTTCAC CTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAATCCAGAACAGACT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487861_chr14_68758601_+_977nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGTTGTTAGAACTGTGGCCAGAGTCAGCCCCAGGT CAGAATGCTGGTCAGCAGCAGACTCACATCCCAGCCCTACCTTCCTGATACCTGATGTGGTGCTCAGAAAAACAAGGAATCCCAGGCTGT TACCCAGTGTCTCCATGTGCCCTCCACAGATGCACTCAACTGTCCTCTCTTCTGCTCTTCCTCCTACAAACTGGGCAACTGGAATCAGAA CAGAGACTTTGGATGAGCATCCAGTGTAACCCAGCCTAGTTTTTCACCACGACTTCCAGATCTACATTTAACATCCGACAGCAACTATAA TTCTACTTTCTGAACCTCCAGGGAAGTTGCTTCCTTGTCCCTTTCAGCAAAGGATGTCATGGTTTTACAATGTCTCCAGTGAAAAAGTTC TTCTTCTCTACATCTTCCTCCCACTCCTACAACCCTTGATCCCCACGTGAGATCTCATTTCCTCCAGCTGGGTCTTCTGCAGAGTGATTA >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000471583_chr14_68758601_+_869nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGGCCAAGAGAAGCCATAGGGATACTGTGACCTTT GTCTAGAGTTGATGGGGGTGTGATTTGTGAAATAAAACAGGACCGTACTGCTTGGAAGAAGGAAACGGAAGCTGACATAATGGGGATTAA TTAGTTGATTGCTGTTGAGATGGTAACAGATTTGCTCCTAAACCATTGAGCTAGCGATTTCAGACCTAGCAGGGAAGGTGAAGATGAAGA AGCCTTTGTTCAGGTCTCTAGATGTGTAGGGCTGAGGGCTTTGCCGCCATGGGATGTCAACAGCCATAATAATAATTTGCACTTATATAG CACCTTTCAACCAGGCACCTCAAAGCGGTTTAACCACATTAATTAATTAAAGCCCACAATCCTCCTGGGGAGAGGAGGAGGATGACTAAC >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000487270_chr14_68758601_+_1929nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAGACAACATTTTGCTCTGTCACCCAAGCTGAAC TGAACTGGGCTCCAGAAATCCTCCCACCTCAGCCTCCTGAGCAGCTAGGACTACAGATGTGCCACCATACCCAGCTAATTTTTTAATTTT TTGTAGAGGTGGGGTCTCATTATGTTGCCCAAGCTGATCTCAAACTCCTGGCTTCAAGAGATCCACCCACCTCAGCCTCCCAAAGCGCTA GGATTACAAGTATGAGACTTTGCCATTCCAATGAGAATTTTGTCCTTAGCAATCTCATCCAATGGCCACTGGAGATGTGTGTAGGGCCAC AAGAATGAGAAAGGGGGCAATGGAGTGACAGGTGACCTGCTCAGGTGCCCCTCCCCAGACCAAATGTCCCAGGCACACAGCCCATGCCCT CCACCATGGAGTACATTTTCTCCCTGGCTTGCTGCTGAGCTAAAGGACCAGGGACGTGGAAACAGGAGGTGAACTAAGGCACCCCGCCAC CCACTGTGGCAGCTTGAATTTCTTGAGGCTGAGACAAACTAGGATCCAGTAGCCTAGATTTTGCCCCAGTTTCTCCACTGAGTATTTACT CAGTGCTCCTGAGCCGATGCCTTCCCCTCTGCCTAGATGAACCACAGCATTTTGGTAAATGCCTCAGCATGTTAGGAGCGCTGGAACGTT TATTCTCTTCCCTCCCAATTATCCACTCTAATGGAGCAGAACACTTACATGGAAAATCCTAAACATGGAAGATGATTTAAAAATGATTCA CCCTGGAATACATGCTTCCAGTTGCTTCTACAGGTTTACCTTGCTAAAGGCATTTCGCTTCCTTTGCTGTTACAATAAGCTTGCCTGCCT TGAAGAAAAGAAGACCAGGGCCAAAGGGAAATCAGTCAAGGGAGCCTGTTTTGTCTGAAATAATGCATCCATGAACAAATGAATTGAGTA TAACTGTCTTTTTACATCAGTGTTTCTGTGGAATTAAGAGAACATCCAAGGCCACTCCTAGCTTGAGTAGATTAAATTTGTCCTTGTGTT TGGAGCAAGGGTTGTGAAGTCTGTCTGGCCCATCAAATGACCAATGGCTTTTAAGGAAGGACTAAGTGACTTATGACCAGAACAAGGGAG CAGCCTGAGTCAGTCTCCCCAATGTCTACATTGTGTTATTTATACTAGCAAAAAAATAGACACAACTAAATGTTCGACCATATGGTATTG GTTAAATTAACATCTATACGATGGAATACTAGATGGTCATTAAAATTATGTGTCAGAAGAAGGCTTAATCTCATGGGAAAGTGTTCACAC CATATTATTAAAGAGAAAAAACAGATTATAAAGCAATATGCATACAATGTAGTAGTTCTGTAAGAAAAAAGTATTATGTGCATTTTAACT GGAAAAATATGTATAAAAATGTTAACAGTGCAATCTCTGGGCAATAAGATTATACTTGACTTTTATTTCTTTTTTGGAATTGTCTTTTTT >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000488612_chr14_68758601_+_904nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAA TCCAGAACAGACTAAAAGAAAATGAGTCCTGAGATTGCTACAGATGAGACCCACCCATCGGAGCCAGGCTTTGAAGGAACTGACCGCAGT GTGCATGAGGAAGTACTTCACGGTGATGACCCTCGCCACCCTCTCAGGAAAACACAGTGACCTCTCCCCCAACATCCCCTTCCCACTCCC AGGTCCCCCGGCAAAGGCAGAAGAACCAAGCAAGCCTTTCCACCAAAGCAGCCATGAACCCCATTCTCATCCTTTCCAAGAACTCTCTGC TATACCAGATAGGGGTTTGGGGTTCTGTTTTCCATTTTTTAAAAAAATCATTTCAAGACTCTTGAACAGTGTGTCGGTTTACACTATTCT ATCTTCTTAAGCCACCATATCAACATATTCACTCTGCTTCCTTTCTTTTCATTTGGCAGATGCCACACTTTTAATGGCAGCAATAAAAGG >In-frame_CD58_ENST00000369487_chr1_117113525_-_RAD51B_ENST00000390683_chr14_68758601_+_482nt GTAGGCGGTGCTTGAACTTAGGGCTGCTTGTGGCTGGGCACTCGCGCAGAGGCCGGCCCGACGAGCCATGGTTGCTGGGAGCGACGCGGG GCGGGCCCTGGGGGTCCTCAGCGTGGTCTGCCTGCTGCACTGCTTTGGTTATCTTGACGAATCAGATTACAACCCATCTGAGTGGAGCCC TGGCTTCTCAGGCAGACCTGGTGTCTCCAGCTGATGATTTGTCCCTGTCTGAAGGCACTTCTGGATCCAGCTGTGTGATAGCCGCACTAG GAAATACCTGGAGTCACAGTGTGAATACCCGGCTGATCCTCCAGTACCTTGATTCAGAGAGAAGACAGATTCTTATTGCCAAGTCCCCTC TGGCTCCCTTCACCTCATTTGTCTACACCATCAAGGAGGAAGGCCTGGTTCTTCAAGAATTTTGGCACATTTGCATATCTGGTTTCTCAA |
Top |
FusionGenePPI for CD58_RAD51B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CD58 | DNAJA1, HERPUD1, CD2, APP, LGALS3, ABHD12B, LGALS8, LGALS9, FUT9, LGALS9C, EGFR, RFC4 | RAD51B | RAD51, RAD51C, RAD51D, XRCC2, SWSAP1, FAM9B, DKKL1, ARL4C, MUC20, ADAMTS4, HELQ |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000390683 | + | 5 | 10 | 1_75 | 252 | 367 | RAD51C |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000471583 | + | 6 | 11 | 1_75 | 252 | 351 | RAD51C |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000487270 | + | 6 | 11 | 1_75 | 252 | 385 | RAD51C |
| Tgene | RAD51B | chr1:117113525 | chr14:68758601 | ENST00000488612 | + | 6 | 12 | 1_75 | 252 | 495 | RAD51C |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CD58_RAD51B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CD58_RAD51B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CD58 | C0026769 | Multiple Sclerosis | 2 | CTD_human |
| Hgene | CD58 | C0079774 | Peripheral T-Cell Lymphoma | 1 | CTD_human |
| Tgene | RAD51B | C0236969 | Substance-Related Disorders | 1 | CTD_human |
| Tgene | RAD51B | C0242788 | Breast Neoplasms, Male | 1 | CTD_human |
| Tgene | RAD51B | C1458155 | Mammary Neoplasms | 1 | CTD_human |
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