	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 6186

FusionGeneSummary for CD44_EXT2

Fusion gene summary

Fusion gene information	Fusion gene name: CD44_EXT2
	Fusion gene ID: 6186
		Hgene	Tgene
	Gene symbol	CD44	EXT2
	Gene ID	960	2132
	Gene name	CD44 molecule (Indian blood group)	exostosin glycosyltransferase 2
	Synonyms	CDW44\|CSPG8\|ECMR-III\|HCELL\|HUTCH-I\|IN\|LHR\|MC56\|MDU2\|MDU3\|MIC4\|Pgp1	SOTV\|SSMS
	Cytomap	11p13	11p11.2
	Type of gene	protein-coding	protein-coding
	Description	CD44 antigenGP90 lymphocyte homing/adhesion receptorHermes antigencell surface glycoprotein CD44chondroitin sulfate proteoglycan 8epicanextracellular matrix receptor IIIhematopoietic cell E- and L-selectin ligandheparan sulfate proteoglycanhoming	exostosin-2N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferaseglucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferasemultiple exostoses protein 2multiple exostosis 2putativ
	Modification date	20180527	20180522
	UniProtAcc	P16070	Q93063
	Ensembl transtripts involved in fusion gene	ENST00000263398, ENST00000526025, ENST00000449691, ENST00000360158, ENST00000415148, ENST00000437706, ENST00000433354, ENST00000428726, ENST00000526669, ENST00000433892, ENST00000278386, ENST00000434472, ENST00000352818, ENST00000528922,	ENST00000533608, ENST00000358681, ENST00000395673, ENST00000343631, ENST00000529186,
Fusion gene scores	* DoF score	11 X 10 X 7=770	5 X 5 X 3=75
	# samples	14	5
	** MAII score	log2(14/770*10)=-2.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CD44 [Title/Abstract] AND EXT2 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation	Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CD44	GO:0030214	hyaluronan catabolic process	17170110
Hgene	CD44	GO:0033138	positive regulation of peptidyl-serine phosphorylation	17045821
Hgene	CD44	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	17045821
Hgene	CD44	GO:0044344	cellular response to fibroblast growth factor stimulus	19577615
Hgene	CD44	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	17045821
Hgene	CD44	GO:0070374	positive regulation of ERK1 and ERK2 cascade	17045821
Hgene	CD44	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	17045821
Tgene	EXT2	GO:0006024	glycosaminoglycan biosynthetic process	12907669
Tgene	EXT2	GO:0033692	cellular polysaccharide biosynthetic process	12907669

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	RV	SARC	TCGA-X6-A8C6-01A	CD44	chr11	35160917	+	EXT2	chr11	44265699	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shit	ENST00000263398	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000263398	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000263398	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000263398	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000263398	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000526025	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000526025	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000526025	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000526025	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000526025	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000449691	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000449691	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000449691	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000449691	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000449691	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000360158	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000360158	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000360158	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000360158	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000360158	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000415148	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000415148	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000415148	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000415148	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000415148	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000437706	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000437706	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000437706	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000437706	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000437706	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000433354	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000433354	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000433354	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000433354	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000433354	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000428726	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000428726	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000428726	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000428726	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000428726	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000526669	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000526669	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000526669	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000526669	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000526669	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000433892	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000433892	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000433892	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000433892	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000433892	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000278386	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000278386	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000278386	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000278386	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000278386	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000434472	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000434472	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000434472	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000434472	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000434472	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000352818	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000352818	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
In-frame	ENST00000352818	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
Frame-shit	ENST00000352818	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
5CDS-intron	ENST00000352818	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
intron-3CDS	ENST00000528922	ENST00000533608	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
intron-3CDS	ENST00000528922	ENST00000358681	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
intron-3CDS	ENST00000528922	ENST00000395673	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
intron-3CDS	ENST00000528922	ENST00000343631	CD44	chr11	35160917	+	EXT2	chr11	44265699	+
intron-intron	ENST00000528922	ENST00000529186	CD44	chr11	35160917	+	EXT2	chr11	44265699	+

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FusionProtFeatures for CD44_EXT2

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CD44 P16070	EXT2 Q93063
	Glycosyltransferase required for the biosynthesis ofheparan-sulfate. The EXT1/EXT2 complex possesses substantiallyhigher glycosyltransferase activity than EXT1 or EXT2 alone.Appears to be a tumor suppressor. Required for the exosomalrelease of SDCBP, CD63 and syndecan (PubMed:22660413).{ECO:0000269\|PubMed:22660413}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for CD44_EXT2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_68aa

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_68aa

* Fusion transcript sequences (only coding sequence (CDS) region).

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_206nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA

* Fusion transcript sequences (Full-length transcript).

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_1284nt
GAGAAGAAAGCCAGTGCGTCTCTGGGCGCAGGGGCCAGTGGGGCTCGGAGGCACAGGCACCCCGCGACACTCCAGGTTCCCCGACCCACG
TCCCTGGCAGCCCCGATTATTTACAGCCTCAGCAGAGCACGGGGCGGGGGCAGAGGGGCCCGCCCGGGAGGGCTGCTACTTCTTAAAACC
TCTGCGGGCTGCTTAGTCACAGCCCCCCTTGCTTGGGTGTGTCCTTCGCTCGCTCCCTCCCTCCGTCTTAGGTCACTGTTTTCAACCTCG
AATAAAAACTGCAGCCAACTTCCGAGGCAGCCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCC
TCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGT
GGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGAC
CATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGG
CAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAG
TAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAAT
ATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTT
GTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGA
CTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAA
TGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCT
GGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGA

>In-frame_CD44_ENST00000263398_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1782nt
GAGAAGAAAGCCAGTGCGTCTCTGGGCGCAGGGGCCAGTGGGGCTCGGAGGCACAGGCACCCCGCGACACTCCAGGTTCCCCGACCCACG
TCCCTGGCAGCCCCGATTATTTACAGCCTCAGCAGAGCACGGGGCGGGGGCAGAGGGGCCCGCCCGGGAGGGCTGCTACTTCTTAAAACC
TCTGCGGGCTGCTTAGTCACAGCCCCCCTTGCTTGGGTGTGTCCTTCGCTCGCTCCCTCCCTCCGTCTTAGGTCACTGTTTTCAACCTCG
AATAAAAACTGCAGCCAACTTCCGAGGCAGCCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCC
TCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGT
GGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGAC
CATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGG
CAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAG
TAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAAT
ATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTT
GTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGA
CTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAA
TGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCT
GGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGA
TTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTA
ACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAG
AAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTT
TTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGT
GACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATG

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_1272nt
AGTGCGTCTCTGGGCGCAGGGGCCAGTGGGGCTCGGAGGCACAGGCACCCCGCGACACTCCAGGTTCCCCGACCCACGTCCCTGGCAGCC
CCGATTATTTACAGCCTCAGCAGAGCACGGGGCGGGGGCAGAGGGGCCCGCCCGGGAGGGCTGCTACTTCTTAAAACCTCTGCGGGCTGC
TTAGTCACAGCCCCCCTTGCTTGGGTGTGTCCTTCGCTCGCTCCCTCCCTCCGTCTTAGGTCACTGTTTTCAACCTCGAATAAAAACTGC
AGCCAACTTCCGAGGCAGCCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCC
TGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCT
GGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAA
GGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAA
CGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAG
GGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCT
CGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCC
AGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAG
AGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCA
GGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCAC
AGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTT

>In-frame_CD44_ENST00000526025_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1770nt
AGTGCGTCTCTGGGCGCAGGGGCCAGTGGGGCTCGGAGGCACAGGCACCCCGCGACACTCCAGGTTCCCCGACCCACGTCCCTGGCAGCC
CCGATTATTTACAGCCTCAGCAGAGCACGGGGCGGGGGCAGAGGGGCCCGCCCGGGAGGGCTGCTACTTCTTAAAACCTCTGCGGGCTGC
TTAGTCACAGCCCCCCTTGCTTGGGTGTGTCCTTCGCTCGCTCCCTCCCTCCGTCTTAGGTCACTGTTTTCAACCTCGAATAAAAACTGC
AGCCAACTTCCGAGGCAGCCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCC
TGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCT
GGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAA
GGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAA
CGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAG
GGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCT
CGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCC
AGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAG
AGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCA
GGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCAC
AGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTT
TTTATTCCTTTTTCTACTGTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTG
GCCTGACAACAGTCTTCTGCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAAT
CATAACCATTTTAAGAACAGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTG
TCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCC
AAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAAC

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_984nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC

>In-frame_CD44_ENST00000449691_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1482nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC
TGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACT
GTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCT
GCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAAC
AGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGG
TCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTT
CTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCT

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_984nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC

>In-frame_CD44_ENST00000360158_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1482nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC
TGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACT
GTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCT
GCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAAC
AGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGG
TCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTT
CTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCT

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_984nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC

>In-frame_CD44_ENST00000415148_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1482nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC
TGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACT
GTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCT
GCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAAC
AGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGG
TCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTT
CTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCT

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_984nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC

>In-frame_CD44_ENST00000437706_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1482nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC
TGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACT
GTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCT
GCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAAC
AGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGG
TCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTT
CTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCT

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_984nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC

>In-frame_CD44_ENST00000433354_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1482nt
CCTCATTGCCCAGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGAT
CCTCCAGCTCCTTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGC
CGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGC
TGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGT
CTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTAC
TTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTG
TTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGA
GGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCAT
TTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAAT
TCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGC
TGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACT
GTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCT
GCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAAC
AGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGG
TCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTT
CTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCT

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_973nt
AGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCC
TTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTG
GCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCC
TGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAG
GCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGG
CATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTT
CTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTG
TTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGG
GGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAA
GCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGAT

>In-frame_CD44_ENST00000428726_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1471nt
AGCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCC
TTTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTG
GCGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCC
TGTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAG
GCTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGG
CATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTT
CTTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTG
TTTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGG
GGAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAA
GCCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGAT
CCTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAAC
ACCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTG
GGAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAG
AAACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGC
CATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTT
TTGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCTGGTATATTTAA

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_972nt
GCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCT
TTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGG
CGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCT
GTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGG
CTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGC
ATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTC
TTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGT
TTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGG
GAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAG
CCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATC

>In-frame_CD44_ENST00000526669_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1470nt
GCGGACCCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCT
TTCGCCCGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGG
CGCAGATCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCT
GTACAAAGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGG
CTGGGACAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGC
ATGCACCCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTC
TTATGATCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGT
TTTCAGTTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGG
GAATCATGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAG
CCAAACATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATC
CTGTCAGTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACA
CCAATTCCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGG
GAACACACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGA
AACCTCCAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCC
ATGCAAGGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTT
TGGTATAAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCTGGTATATTTAAA

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_966nt
CCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCC
CGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGA
TCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAA
AGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGA
CAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCAC
CCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGA
TCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAG
TTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCA
TGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAAC
ATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCA

>In-frame_CD44_ENST00000433892_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1464nt
CCCAGCCTCTGCCAGGTTCGGTCCGCCATCCTCGTCCCGTCCTCCGCCGGCCCCTGCCCCGCGCCCAGGGATCCTCCAGCTCCTTTCGCC
CGCGCCCTCCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGA
TCGGTCAGAGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAA
AGATGACTTTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGA
CAGAGGGAGAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCAC
CCACCTAACCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGA
TCTCTGATGGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAG
TTCCATGTAACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCA
TGTAAAGGGTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAAC
ATCTTGGTGGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCA
GTTCCATGAGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACACCAATT
CCTGATAGTCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGGGAACAC
ACGCCAGGAGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGAAACCTC
CAGAGGAATCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAA
GGAGTCGCTCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTAT
AAACTTAACATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCTGGTATATTTAAATCATTA

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_868nt
CCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAG
AGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACT
TTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGA
GAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAA
CCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGAT
GGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGT
AACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGG
GTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGT
GGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATG

>In-frame_CD44_ENST00000278386_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1366nt
CCGTTCGCTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAG
AGTGCATCAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACT
TTCCTGAGAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGA
GAGAACAAGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAA
CCCACTTTCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGAT
GGGTTCTTCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGT
AACAATCTGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGG
GTACCCAGACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGT
GGGATTTGATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATG
AGCTATTCCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACACCAATTCCTGATAG
TCCAAGGAACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGGGAACACACGCCAGG
AGGAATGTCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGAAACCTCCAGAGGAA
TCTGTTTGCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAAGGAGTCGC
TCTAGCTGGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTATAAACTTAA
CATTAGCCAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCTGGTATATTTAAATCATTAAATTTCAG

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_861nt
CTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCAT
CAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGA
GAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACA
AGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTT
TCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCT
TCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATC
TGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCA
GACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTT
GATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATT

>In-frame_CD44_ENST00000434472_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1359nt
CTCCGGACACCATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCAT
CAACAAGTTTGCTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGA
GAAGCTGAAGAGCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACA
AGGCCTCCCAGCACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTT
TCTCAAGAACAAGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCT
TCTCGAAAATGCCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATC
TGGAAGGAAACTTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCA
GACCTCACTTTTAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTT
GATAAATGCCTTGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATT
CCTCTTTGGTTTGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACACCAATTCCTGATAGTCCAAGG
AACCACCTTTCTCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGGGAACACACGCCAGGAGGAATG
TCTGATACCCTCTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGAAACCTCCAGAGGAATCTGTTT
GCTTCCTGATTAGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAAGGAGTCGCTCTAGCT
GGTACCCGTAAAAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTATAAACTTAACATTAGC
CAGGGAGGTTCTGGCTAACGTTAAATGCTGCTATACAACTGCTTTGCAACAGTTGCTGGTATATTTAAATCATTAAATTTCAGCATTTAC

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000358681_chr11_44265699_+_850nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA
GCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAG
CACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACA
AGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATG
CCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAAC
TTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTT
TAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCT
TGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTT

>In-frame_CD44_ENST00000352818_chr11_35160917_+_EXT2_ENST00000395673_chr11_44265699_+_1348nt
ATGGACAAGTTTTGGTGGCACGCAGCCTGGGGACTCTGCCTCGTGCCGCTGAGCCTGGCGCAGATCGGTCAGAGTGCATCAACAAGTTTG
CTTCAGTCTTCGGGACCATGCCTCTCAAGGTGGTGGAACACCGAGCTGACCCTGTCCTGTACAAAGATGACTTTCCTGAGAAGCTGAAGA
GCTTCCCCAACATTGGCAGCTTATGAAACGTGTCATTGGTGGAGGTCTGAATGTGAGGCTGGGACAGAGGGAGAGAACAAGGCCTCCCAG
CACTCTGATGTCAGAGTAGTAGGTTAAGGGTGGAAGGTTGACCTACTTGGATCTTGGCATGCACCCACCTAACCCACTTTCTCAAGAACA
AGAACCTAGAATGAATATCCAAGCACCTCGAGCTATGCAACCTCTGTTCTTGTATTTCTTATGATCTCTGATGGGTTCTTCTCGAAAATG
CCAAGTGGAAGACTTTGTGGCATGCTCCAGATTTAAATCCAGCTGAGGCTCCCTTTGTTTTCAGTTCCATGTAACAATCTGGAAGGAAAC
TTCACGGACAGGAAGACTGCTGGAGAAGAGAAGCGTGTTAGCCCATTTGAGGTCTGGGGAATCATGTAAAGGGTACCCAGACCTCACTTT
TAGTTATTTACATCAATGAGTTCTTTCAGGGAACCAAACCCAGAATTCGGTGCAAAAGCCAAACATCTTGGTGGGATTTGATAAATGCCT
TGGGACCTGGAGTGCTGGGCTTGTGCACAGGAAGAGCACCAGCCGCTGAGTCAGGATCCTGTCAGTTCCATGAGCTATTCCTCTTTGGTT
TGGCTTTTTGATATGATTAAAATTATTTTTTATTCCTTTTTCTACTGTGTCTTAAACACCAATTCCTGATAGTCCAAGGAACCACCTTTC
TCCCTTGATATATTTAACTCCGTCTTTGGCCTGACAACAGTCTTCTGCCCATGTCTGGGAACACACGCCAGGAGGAATGTCTGATACCCT
CTGCATCAAGCGTAAGAAGGTCCCAAATCATAACCATTTTAAGAACAGATGACTCAGAAACCTCCAGAGGAATCTGTTTGCTTCCTGATT
AGATCCAGTCAATGTTTTAAAGGTATTGTCAGAGAAAAACAGAGGGTCTGTACTAGCCATGCAAGGAGTCGCTCTAGCTGGTACCCGTAA
AAGTTGTGGGAATTGTGACCCCCATCCCAAGGGGATGCCAAAATTTCTCTCATTCTTTTGGTATAAACTTAACATTAGCCAGGGAGGTTC

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FusionGenePPI for CD44_EXT2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene	Hgene's interactors	Tgene	Tgene's interactors
CD44	ARHGEF1, COL14A1, LCK, IGFBP3, MMP7, ERBB4, TIAM1, TGFBR1, VAV2, FN1, EGFR, ERBB2, HBEGF, EZR, VCAN, SRC, PTPRC, FYN, MSN, NF2, ELAVL1, PRKCZ, ITGB1, FLOT2, CAV1, EP300, STAT3, SLC3A2, IQGAP1, FMNL1, ATF2, ANK1, VHL, BAG1, DPP8, ABCE1, AIM1, DBN1, FLNA, MYH9, DYNLL1, SYNPO, LIMA1, MYO19, SQSTM1, CHERP, PHRF1, CDC73, CD44, FGFR1, CTDSPL, GMEB2, FGF2, GMEB1, DHRS2, METTL8, FAM115C, SLC39A9, AMPD2, SNX33, CAMKV, ATG9A, PRDM10, C17orf80, SNX18, FGFR2, FGFRL1, VANGL1, PARP2, TEFM, LAMA3, MTCH2, HADHB, CLCN7, XAB2, GTF3C2, CDC40, GTF3C3, AQR, GTF3C1, GTF3C6, HADHA, TMEM160, OSBPL8, CDC5L, TNPO2, PRKCI, LEMD3, LGALS1, RBM22, VANGL2, MBOAT7, ISY1, GBAS, TRIM25, CD74	EXT2	STK16, SNCG, HYOU1, CNTF, TCEB1, RPS29, CRB1, CLEC2L, FABP4, HNF4A, EXT1, EXT2, GALNT5, TRAP1, TK1, CDKN1A, SMN1, ANXA7, PFDN1, GSKIP, SLC22A2, IDS, INVS, TTC19, RBFA, AFAP1, ATE1, CUX1, USP30, NOP9, HLA-DPB1

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for CD44_EXT2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Hgene	CD44	P16070	DB08818	Hyaluronic acid	CD44 antigen	small molecule	approved\|vet_approved

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RelatedDiseases for CD44_EXT2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CD44	C0023487	Acute Promyelocytic Leukemia	2	CTD_human
Hgene	CD44	C0011616	Contact Dermatitis	1	CTD_human
Hgene	CD44	C0017661	IGA Glomerulonephritis	1	CTD_human
Hgene	CD44	C0023467	Leukemia, Myelocytic, Acute	1	CTD_human
Hgene	CD44	C0024668	Mammary Neoplasms, Experimental	1	CTD_human
Hgene	CD44	C0027627	Neoplasm Metastasis	1	CTD_human
Hgene	CD44	C0027746	Nerve Degeneration	1	CTD_human
Hgene	CD44	C0030297	Pancreatic Neoplasm	1	CTD_human
Hgene	CD44	C0037274	Dermatologic disorders	1	CTD_human
Hgene	CD44	C0038356	Stomach Neoplasms	1	CTD_human
Hgene	CD44	C0042900	Vitiligo	1	CTD_human
Hgene	CD44	C0311375	Arsenic Poisoning	1	CTD_human
Hgene	CD44	C2609414	Acute kidney injury	1	CTD_human
Tgene	EXT2	C1851413	EXOSTOSES, MULTIPLE, TYPE II	9	CTD_human;UNIPROT
Tgene	EXT2	C0015306	Hereditary Multiple Exostoses	1	CTD_human;HPO;ORPHANET
Tgene	EXT2	C4225248	SEIZURES, SCOLIOSIS, AND MACROCEPHALY SYNDROME	1	ORPHANET;UNIPROT

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Fusion gene ID: 6186

FusionGeneSummary for CD44_EXT2

FusionProtFeatures for CD44_EXT2

FusionGeneSequence for CD44_EXT2

FusionGenePPI for CD44_EXT2

RelatedDrugs for CD44_EXT2

RelatedDiseases for CD44_EXT2