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Fusion gene ID: 6127 |
FusionGeneSummary for CD109_NPHP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CD109_NPHP1 | Fusion gene ID: 6127 | Hgene | Tgene | Gene symbol | CD109 | NPHP1 | Gene ID | 135228 | 4867 |
| Gene name | CD109 molecule | nephrocystin 1 | |
| Synonyms | CPAMD7|p180|r150 | JBTS4|NPH1|SLSN1 | |
| Cytomap | 6q13 | 2q13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CD109 antigen150 kDa TGF-beta-1-binding proteinC3 and PZP-like alpha-2-macroglobulin domain-containing protein 7Gov platelet alloantigensactivated T-cell marker CD109platelet-specific Gov antigen | nephrocystin-1juvenile nephronophthisis 1 proteinnephronophthisis 1 (juvenile) | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q6YHK3 | O15259 | |
| Ensembl transtripts involved in fusion gene | ENST00000422508, ENST00000437994, ENST00000287097, ENST00000474094, | ENST00000316534, ENST00000445609, ENST00000393272, ENST00000355301, ENST00000417665, ENST00000418527, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 2 X 2 X 2=8 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: CD109 [Title/Abstract] AND NPHP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CD109 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 16754747 |
| Hgene | CD109 | GO:0061045 | negative regulation of wound healing | 16754747 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | W33075 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000422508 | ENST00000316534 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000422508 | ENST00000445609 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000422508 | ENST00000393272 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000422508 | ENST00000355301 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000422508 | ENST00000417665 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-intron | ENST00000422508 | ENST00000418527 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000437994 | ENST00000316534 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000437994 | ENST00000445609 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000437994 | ENST00000393272 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000437994 | ENST00000355301 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000437994 | ENST00000417665 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| 5CDS-intron | ENST00000437994 | ENST00000418527 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000287097 | ENST00000316534 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000287097 | ENST00000445609 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000287097 | ENST00000393272 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000287097 | ENST00000355301 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| In-frame | ENST00000287097 | ENST00000417665 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| 5CDS-intron | ENST00000287097 | ENST00000418527 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000474094 | ENST00000316534 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000474094 | ENST00000445609 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000474094 | ENST00000393272 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000474094 | ENST00000355301 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-3CDS | ENST00000474094 | ENST00000417665 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
| intron-intron | ENST00000474094 | ENST00000418527 | CD109 | chr6 | 74440297 | + | NPHP1 | chr2 | 110920711 | - |
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FusionProtFeatures for CD109_NPHP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CD109 | NPHP1 |
| Together with BCAR1 it may play a role in the control ofepithelial cell polarity. Involved in the organization of apicaljunctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8(By similarity). Does not seem to be strictly required forciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2to cell matrix adhesions, thereby initiating phosphorylation ofPTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role inthe regulation of intraflagellar transport (IFT) during ciliaassembly. Required for normal retina development. In connectingphotoreceptor cilia influences the movement of some IFT proteinssuch as IFT88 and WDR19. Involved in spermatogenesis (Bysimilarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CD109_NPHP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_590aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKQINTVDVLTTM GAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFD GNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPI PAKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLL KDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETAR >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_590aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKQINTVDVLTTM GAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFD GNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPI PAKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLL KDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETAR >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_589aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARW >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_589aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARW >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_624aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKLSKPVSPREGKKKWPELYHILKTMHCSCLPCTKIMRDKEFLK >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_590aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKQINTVDVLTTM GAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFD GNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPI PAKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLL KDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETAR >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_590aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKQINTVDVLTTM GAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFD GNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPI PAKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLL KDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETAR >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_589aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARW >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_589aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARW >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_624aa MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTL PSLPLNSADEITELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKINTVDVLTTMG AIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDG NKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISTIRNSTGERGELSCGWVFLKLFDASGVPIP AKTTELFLNGGTPTEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFTRQILGDVLLK DRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKLSKPVSPREGKKKWPELYHILKTMHCSCLPCTKIMRDKEFLK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_1770nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATG GGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCA GAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTG ATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGAT GGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACT CGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATT TCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATT CCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACAC GGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTA CTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTG AAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATG GATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTC CTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGG TGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_1770nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATG GGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCA GAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTG ATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGAT GGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACT CGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATT TCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATT CCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACAC GGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTA CTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTG AAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATG GATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTC CTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGG TGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_1767nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTG GTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGG AAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_1767nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTG GTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGG AAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_1872nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGCTCTCAAAGCCTGTATCACCAAGAGAAGGGAAAAAA AAATGGCCTGAGCTGTACCATATATTGAAAACAATGCATTGCTCCTGCTTACCTTGCTATAAAATCATGAGAGACAAAGAGTTCCTGAAG TCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACT GAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGA >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_1770nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATG GGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCA GAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTG ATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGAT GGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACT CGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATT TCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATT CCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACAC GGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTA CTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTG AAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATG GATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTC CTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGG TGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCT >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_1770nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATG GGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCA GAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTG ATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGAT GGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACT CGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATT TCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATT CCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACAC GGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTA CTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTG AAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATG GATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTC CTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGG TGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCT >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_1767nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTG GTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGG AAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTT >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_1767nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTG GTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGG AAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTT >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_1872nt ATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTG ACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCG GAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTT CCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACC CGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATT GTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGA GCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAG CTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATT CTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGT AATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGC ATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCT TATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCA GCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGC AGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTA AGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAA GACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGAT GCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGCTCTCAAAGCCTGTATCACCAAGAGAAGGGAAAAAA AAATGGCCTGAGCTGTACCATATATTGAAAACAATGCATTGCTCCTGCTTACCTTGCTATAAAATCATGAGAGACAAAGAGTTCCTGAAG TCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACT GAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_3681nt ATAGTTGCTATGAATTTCTCCTCACAAGGATGGGCCTGTTTACTCACCCTGGGCATCGTTGGTAGAGCGCTAGTGTAAACAGCCTGAGGA ACCCGGTGGGCCGGGGAAGTGGGCGCGCTCTGTTCTCCGCGGCCAGCTGGGACGCCGGGCCAGGTGGGGCCGCCTGCGTTTAGCAACTGC TTTCTCACCCCCTGGATTTGCGATGTTTGCCACAGCAGCGAGAAGCGCCATTGTAATGGGGATGGGAGGGGTGGAGCCTCCAAGTCCTGT CTCAATTTAGATCTCTCACTCTGCTGTTAGGCGCGCCCATTTCAGATTACTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGT GGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGTAGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCC TGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCA GGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCAT CAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACA GTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCA AGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATT TTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGT TCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAAC TGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCT GTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCA ACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGC TTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAA CTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGC TTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGA TTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAA CATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGC AAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGT GGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCG TGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACT TCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGA CCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTC CACGATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTACAACTTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTT AAAGAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATAAATTTTTATAAGGAATACTGTTATATCTAAATTTAAACAGT ATTTATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTATAAAAGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCA AGAAAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATCATCTAACTGATAAAGGTCTAGTATCCAAAATATTTAAATTT ATGAGTGTTAATAAAATTTATCTTGTTCAATGAAGAGGAAGTTAAAGTGATCCATTTGAGAAAGTTGTATCACTTAATTCAGTCTGATAC TTGAATGTGATTTACCCCTAATTAAGTACAAAAACAGAGTCGCTTTTGCCTTTTCAAATCAAGAAAATAAGTGCTCTGTCAAAAGCACAA AAAGAAACTTTCAGGCACTGGAGAGTGGAGTCGACTCACCCTTTCAGGCCTTGTTGCATCTCAGATAAACCTGTGACTGCTGGTAAAATA ATGTCCCAAGCCTTTCCTTTTAGTGATAAACAGTAGCAGCCTGCGTTAATTGAGCACCTACTGTGTGTCTGAGCATTTCTCATTAGCCCA GTTAATCCTCACACCTACTGTAGGAGATAGGTACTGTTGTTTTTTATTACCGCCGAAGAAACAGGCCAGATAAGTGAAGTAATTTGCCTA AGGTCACAGCTAATAAGTGGCACAGCTAATATTCCCAGTAAAGATACCATGTATAATTTTCTACAACCTAAGATGTTCTGCCTTATCGGG GCGAACCTTTTAGGATTCCATGTGAAAATAAAATATGAGGAAAAGTTTAACCTAAATAATTAGAATCCCATTAGAGGTACTTTTTTTTGA TGGCATGCTGCCTTAAAAGAGCCATTTATTTTTAGAGATCTGTCATATTATGAAAGTTCTGGGCTATCTTAGCTAACTTATCCTAAACCC TTAACCTAAATTTAACTTGAGCCCCAGTCTCAGAAATTAACATGGTATGAAGGTGTTTCCAGGCCAGGCGCGGTGGCTCACGCCTGTAAT CCCAACACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACACTATCTGTACTAAAAACACA AAATTAGCTGGGCGTGGTAGTGCGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGTAGAAGAATTGTTTGAACCTGGGAGGTGGAGGT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_2656nt ATAGTTGCTATGAATTTCTCCTCACAAGGATGGGCCTGTTTACTCACCCTGGGCATCGTTGGTAGAGCGCTAGTGTAAACAGCCTGAGGA ACCCGGTGGGCCGGGGAAGTGGGCGCGCTCTGTTCTCCGCGGCCAGCTGGGACGCCGGGCCAGGTGGGGCCGCCTGCGTTTAGCAACTGC TTTCTCACCCCCTGGATTTGCGATGTTTGCCACAGCAGCGAGAAGCGCCATTGTAATGGGGATGGGAGGGGTGGAGCCTCCAAGTCCTGT CTCAATTTAGATCTCTCACTCTGCTGTTAGGCGCGCCCATTTCAGATTACTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGT GGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGTAGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCC TGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCA GGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCAT CAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACA GTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCA AGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATT TTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACACTGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGT TCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAAC TGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCT GTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCA ACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGC TTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAA CTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGC TTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGA TTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAA CATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGC AAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGT GGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCG TGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACT TCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGA CCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTC CACGATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTACAACTTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTT AAAGAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATAAATTTTTATAAGGAATACTGTTATATCTAAATTTAAACAGT ATTTATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTATAAAAGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCA AGAAAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATCATCTAACTGATAAAGGTCTAGTATCCAAAATATTTAAATTT >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_2653nt ATAGTTGCTATGAATTTCTCCTCACAAGGATGGGCCTGTTTACTCACCCTGGGCATCGTTGGTAGAGCGCTAGTGTAAACAGCCTGAGGA ACCCGGTGGGCCGGGGAAGTGGGCGCGCTCTGTTCTCCGCGGCCAGCTGGGACGCCGGGCCAGGTGGGGCCGCCTGCGTTTAGCAACTGC TTTCTCACCCCCTGGATTTGCGATGTTTGCCACAGCAGCGAGAAGCGCCATTGTAATGGGGATGGGAGGGGTGGAGCCTCCAAGTCCTGT CTCAATTTAGATCTCTCACTCTGCTGTTAGGCGCGCCCATTTCAGATTACTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGT GGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGTAGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCC TGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCA GGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCAT CAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACA GTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCA AGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATT TTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCA GGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGG CCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTA AAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACA TTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTG ATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTG GTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTT TCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTA TGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACAT TAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAA GTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGG CTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGC TCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCC TTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCT ATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTCCAC GATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTACAACTTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTTAAA GAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATAAATTTTTATAAGGAATACTGTTATATCTAAATTTAAACAGTATT TATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTATAAAAGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCAAGA AAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATCATCTAACTGATAAAGGTCTAGTATCCAAAATATTTAAATTTATG >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_2281nt ATAGTTGCTATGAATTTCTCCTCACAAGGATGGGCCTGTTTACTCACCCTGGGCATCGTTGGTAGAGCGCTAGTGTAAACAGCCTGAGGA ACCCGGTGGGCCGGGGAAGTGGGCGCGCTCTGTTCTCCGCGGCCAGCTGGGACGCCGGGCCAGGTGGGGCCGCCTGCGTTTAGCAACTGC TTTCTCACCCCCTGGATTTGCGATGTTTGCCACAGCAGCGAGAAGCGCCATTGTAATGGGGATGGGAGGGGTGGAGCCTCCAAGTCCTGT CTCAATTTAGATCTCTCACTCTGCTGTTAGGCGCGCCCATTTCAGATTACTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGT GGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGTAGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCC TGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCA GGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCAT CAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACA GTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCA AGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATT TTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCA GGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGG CCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTA AAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACA TTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTG ATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTG GTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTT TCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTA TGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACAT TAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAA GTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGG CTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGC TCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCC TTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCT ATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTCCAC >In-frame_CD109_ENST00000437994_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_2386nt ATAGTTGCTATGAATTTCTCCTCACAAGGATGGGCCTGTTTACTCACCCTGGGCATCGTTGGTAGAGCGCTAGTGTAAACAGCCTGAGGA ACCCGGTGGGCCGGGGAAGTGGGCGCGCTCTGTTCTCCGCGGCCAGCTGGGACGCCGGGCCAGGTGGGGCCGCCTGCGTTTAGCAACTGC TTTCTCACCCCCTGGATTTGCGATGTTTGCCACAGCAGCGAGAAGCGCCATTGTAATGGGGATGGGAGGGGTGGAGCCTCCAAGTCCTGT CTCAATTTAGATCTCTCACTCTGCTGTTAGGCGCGCCCATTTCAGATTACTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGT GGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGTAGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCC TGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGCTCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCA GGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCCTTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCAT CAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGGCTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACA GTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGAGATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCA AGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAAGCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATT TTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCA GGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGG CCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTA AAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACA TTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTG ATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTG GTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTT TCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTA TGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACAT TAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAA GTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGG CTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGCTCTCAAAGCCTGTATCACCAAGAGAAGGGAAAAAAAAATGGCCTGAGCTGTACC ATATATTGAAAACAATGCATTGCTCCTGCTTACCTTGCTATAAAATCATGAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTT ACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAG TTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACC TTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCCTCTAGCCCTCAGCTTCCCACGGAATC >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000316534_chr2_110920711_-_3362nt CTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGTGGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGT AGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGC TCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCC TTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGG CTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGA GATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAA GCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACAC TGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCG AGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTC GAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACA TGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATG GACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGG AATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTT TGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCC TTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTT GAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACA AATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCT CTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGA GTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGA AGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTC ACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCA GCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTCCACGATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTAC AACTTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTTAAAGAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATA AATTTTTATAAGGAATACTGTTATATCTAAATTTAAACAGTATTTATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTAT AAAAGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCAAGAAAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATC ATCTAACTGATAAAGGTCTAGTATCCAAAATATTTAAATTTATGAGTGTTAATAAAATTTATCTTGTTCAATGAAGAGGAAGTTAAAGTG ATCCATTTGAGAAAGTTGTATCACTTAATTCAGTCTGATACTTGAATGTGATTTACCCCTAATTAAGTACAAAAACAGAGTCGCTTTTGC CTTTTCAAATCAAGAAAATAAGTGCTCTGTCAAAAGCACAAAAAGAAACTTTCAGGCACTGGAGAGTGGAGTCGACTCACCCTTTCAGGC CTTGTTGCATCTCAGATAAACCTGTGACTGCTGGTAAAATAATGTCCCAAGCCTTTCCTTTTAGTGATAAACAGTAGCAGCCTGCGTTAA TTGAGCACCTACTGTGTGTCTGAGCATTTCTCATTAGCCCAGTTAATCCTCACACCTACTGTAGGAGATAGGTACTGTTGTTTTTTATTA CCGCCGAAGAAACAGGCCAGATAAGTGAAGTAATTTGCCTAAGGTCACAGCTAATAAGTGGCACAGCTAATATTCCCAGTAAAGATACCA TGTATAATTTTCTACAACCTAAGATGTTCTGCCTTATCGGGGCGAACCTTTTAGGATTCCATGTGAAAATAAAATATGAGGAAAAGTTTA ACCTAAATAATTAGAATCCCATTAGAGGTACTTTTTTTTGATGGCATGCTGCCTTAAAAGAGCCATTTATTTTTAGAGATCTGTCATATT ATGAAAGTTCTGGGCTATCTTAGCTAACTTATCCTAAACCCTTAACCTAAATTTAACTTGAGCCCCAGTCTCAGAAATTAACATGGTATG AAGGTGTTTCCAGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGT TTGAGACCAGCCTGGCCAACACTATCTGTACTAAAAACACAAAATTAGCTGGGCGTGGTAGTGCGTGCCTGTAATCCCAGCTACTTGGGA GGCTGAGGTAGAAGAATTGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCCAGCCTAGGCAACAAGAG >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000445609_chr2_110920711_-_2337nt CTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGTGGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGT AGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGC TCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCC TTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGG CTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGA GATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAA GCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGCAGATAAACAC TGTTGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCG AGCAAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTC GAGACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACA TGTACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATG GACCTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGG AATATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTT TGATGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCC TTCAATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTT GAACAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACA AATTCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCT CTTGGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGA GTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGA AGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTC ACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCA GCCTCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTCCACGATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTAC AACTTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTTAAAGAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATA AATTTTTATAAGGAATACTGTTATATCTAAATTTAAACAGTATTTATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTAT AAAAGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCAAGAAAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATC >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000393272_chr2_110920711_-_2334nt CTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGTGGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGT AGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGC TCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCC TTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGG CTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGA GATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAA GCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGT TGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGC AAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAG ACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGT ACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGAC CTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAAT ATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGA TGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTC AATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAA CAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAAT TCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTT GGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTT CCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGA AGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACC AGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCC TCTAGCCCTCAGCTTCCCACGGAATCAGATGGATCCTCCACGATTACGTGAATAAAATGATGGAACCAAAAATCACTGTCACTTTACAAC TTAGGTTTTACTCTTTTCTTTCTACAGACCATATTTTTAAAGAAATGTTTATACAATAATTTAAATATTTTTTAAAACCATAAAATAAAT TTTTATAAGGAATACTGTTATATCTAAATTTAAACAGTATTTATTTTTTCAAAAACAGCTACTTAAGTTAATGGTATAGATTTCTATAAA AGCAAGATTTTGTCAAAAACTAAATTTATGATTATTCAAGAAAGTGAAAAAAACAACCTACAGAATGGGAAAACATATTTGCAAATCATC >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000355301_chr2_110920711_-_1962nt CTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGTGGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGT AGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGC TCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCC TTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGG CTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGA GATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAA GCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGT TGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGC AAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAG ACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGT ACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGAC CTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAAT ATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGA TGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTC AATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAA CAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAAT TCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTT GGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGAGAGACAAAGAGTT CCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATTCAGGTGGGCAGAAGA AGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCAAGCTCTGCTGTCACC AGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGTGTGACAGTGGCAGCC >In-frame_CD109_ENST00000287097_chr6_74440297_+_NPHP1_ENST00000417665_chr2_110920711_-_2067nt CTAAACTCGAATTAAGAGGGAAAAAAAATCAGGGAGGAGGTGGCAAGCCACACCCCACGGTGCCCGCGAACTTCCCCGGCAGCGGACTGT AGCCCAGGCAGACGCCGTCGAGATGCAGGGCCCACCGCTCCTGACCGCCGCCCACCTCCTCTGCGTGTGCACCGCCGCGCTGGCCGTGGC TCCCGGGCCTCGGTTTCTGGTGACAGCCCCAGGGATCATCAGGCCCGGAGGAAATGTGACTATTGGGGTGGAGCTTCTGGAACACTGCCC TTCACAGGTGACTGTGAAGGCGGAGCTGCTCAAGACAGCATCAAACCTCACTGTCTCTGTCCTGGAAGCAGAAGGAGTCTTTGAAAAAGG CTCTTTTAAGACACTTACTCTTCCATCACTACCTCTGAACAGTGCAGATGAGATTTATGAGCTACGTGTAACCGGACGTACCCAGGATGA GATTTTATTCTCTAATAGTACCCGCTTATCATTTGAGACCAAGAGAATATCTGTCTTCATTCAAACAGACAAGGCCTTATACAAGCCAAA GCAAGAAGTGAAGTTTCGCATTGTTACACTCTTCTCAGATTTTAAGCCTTACAAAACCTCTTTAAACATTCTCATTAAGATAAACACTGT TGATGTGTTAACTACGATGGGAGCTATTCCTGCAGGGTTCAGGCCTTCCACGCTCTCACAGCTTCTGGAGGAAGGGAATCAATTTCGAGC AAATTACTTCTTACAACCAGAGCTCATGCCTTCACAACTGGCCTTCAGAGATCTGATGTGGGATGCTACAGAAGGCACTATTAGGTCGAG ACCAAGTCGTATTTCATTGATTCTGACATTATGGAGCTGTAAAATGATTCCTCTTCCAGGAATGAGCATACAGGTTCTCAGCAGACATGT ACGCCTCTGTCTATTTGATGGTAATAAGGTTCTGAGCAACATTCATACAGTCAGAGCCACATGGCAACCTAAAAAGCCCAAAACATGGAC CTTTTCTCCCCAGGTTACTCGCATCTTACCATGTTTGCTTGATGGTGATTGCTTTATCAGGTCTAATTCTGCATCTCCAGATCTTGGAAT ATTATTTGAACTTGGAATTTCTTATATTCGCAATTCAACTGGTGAAAGAGGAGAGTTAAGCTGTGGCTGGGTGTTTCTTAAACTTTTTGA TGCCAGTGGAGTTCCTATTCCAGCAAAAACTTATGAGCTTTTCTTGAATGGTGGTACTCCTTATGAAAAAGGTATTGAAGTGGACCCTTC AATATCCAGAAGAGCACACGGCAGTGTTTTCTACCAGATTATGACAATGAGAAGGCAGCCTCAACTTCTAGTGAAACTGAGATCCTTGAA CAGAAGATCAAGAAATGTACTAAGTCTACTGCCAGAAACATTAATTGGAAATATGTGTTCTATTCACTTGTTGATATTTTATCGACAAAT TCTTGGAGATGTGCTCCTGAAAGACAGGATGAGCTTGCAAAGTACTGATTTAATTAGCCATCCCATGCTGGCCACCTTCCCCATGCTCTT GGAGCAGCCTGATGTGATGGATGCTCTCAGGAGTTCGTGGGCTGGAAAAGAAAGCACATTAAAAAGATCAGAGAAGCTCTCAAAGCCTGT ATCACCAAGAGAAGGGAAAAAAAAATGGCCTGAGCTGTACCATATATTGAAAACAATGCATTGCTCCTGCTTACCTTGCTATAAAATCAT GAGAGACAAAGAGTTCCTGAAGTCCACGTTTCTCCTGGTTTACCATGACTGCGTGCTCCCACTTCTCCACTCCACACGCCTACCCCCATT CAGGTGGGCAGAAGAAGAGACTGAGACTGCACGGTGGAAAGTTATCACTGACTTCCTTAAGCAAAACCAAGAAAACCAGGGCGCCCTCCA AGCTCTGCTGTCACCAGACGGAGTTCATGAACCTTTTGACCTTTCAGAGCAGACCTATGACTTCTTGGGTGAAATGAGAAAGAATGCAGT |
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FusionGenePPI for CD109_NPHP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CD109 | FCGR3B, LGALS3, TAZ, CELA2B, LGALS9, TMEM185A, PTPRK, ISLR, ERLIN2, RNASE13, MYH9, SYNPO, MAPRE1, MYO5C, CAPN1, SCGB1D1, CYP19A1, SCGB1D4, IFNA21, PRSS33, ENPP7, IFNE, PRSS37, GJB7, MTUS2, CCL22, DKKL1, C4orf26, DEFA5, ST8SIA4, PCDHGC3, TRIM25 | NPHP1 | INVS, TUBB, NPHP3, NPHP1, FLNA, FLNB, BCAR1, NPHP4, PTK2B, TNS1, KHDRBS1, TNK2, ARHGAP32, UBQLN4, ADAM15, MED28, CEP164, CEP128, AGK, ATP2B1, BAIAP2L1, BCAS3, TMEM256, CACYBP, CBL, CEP170, CHTOP, CLTC, COPA, DBT, DNM2, DNMBP, DYNC1H1, ECD, FCHO2, FKBP4, GARS, GPATCH1, HK1, HSDL2, HYOU1, IDH3B, IQGAP1, KDELR2, MOB4, NARS, NDUFS3, NDUFV1, NNT, NUDCD3, PDRG1, PHACTR4, PIH1D1, POLR2E, PRRC2A, PSMD14, PSMD7, RAB35, RAB3GAP1, RAB6A, RPAP3, RPGRIP1L, SEC23IP, SEC63, SH3D19, SNX9, SRSF2, TM9SF3, TMEM237, TNRC6B, TTLL12, UNC45A, UQCRC1, URI1, USP22, UXT, WDR41, WDR92, XPO7, BAG2, FLII, WDR83, KCNA5, DNAJC7, RPGR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CD109_NPHP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CD109_NPHP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CD109 | C0009404 | Colorectal Neoplasms | 2 | CTD_human |
| Hgene | CD109 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Tgene | NPHP1 | C0022658 | Kidney Diseases | 1 | CTD_human;HPO |
| Tgene | NPHP1 | C1855681 | Nephronophthisis, familial juvenile | 1 | CTD_human;ORPHANET;UNIPROT |
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