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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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Fusion gene ID: 60

FusionGeneSummary for AASDH_CC2D2A

check button Fusion gene summary
Fusion gene informationFusion gene name: AASDH_CC2D2A
Fusion gene ID: 60
HgeneTgene
Gene symbol

AASDH

CC2D2A

Gene ID

132949

57545

Gene nameaminoadipate-semialdehyde dehydrogenasecoiled-coil and C2 domain containing 2A
SynonymsACSF4|LYS2|NRPS1098|NRPS998JBTS9|MKS6
Cytomap

4q12

4p15.32

Type of geneprotein-codingprotein-coding
Descriptionbeta-alanine-activating enzyme2-aminoadipic 6-semialdehyde dehydrogenaseacyl-CoA synthetase family member 4non-ribosomal peptide synthetase 1098non-ribosomal peptide synthetase 998coiled-coil and C2 domain-containing protein 2A
Modification date2018051920180519
UniProtAcc

Q4L235

Q9P2K1

Ensembl transtripts involved in fusion geneENST00000513376, ENST00000205214, 
ENST00000434343, ENST00000451613, 
ENST00000602986, ENST00000502617, 
ENST00000510762, 		ENST00000424120, 
ENST00000413206, ENST00000503292, 
ENST00000389652, ENST00000438599, 
ENST00000511544, ENST00000513811, 
ENST00000507954, ENST00000515124, 
ENST00000503658, 
Fusion gene scores* DoF score5 X 5 X 3=754 X 4 X 2=32
# samples 54
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: AASDH [Title/Abstract] AND CC2D2A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVKIRCTCGA-CW-5581-01AAASDHchr4

57244314

-CC2D2Achr4

15564978

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000513376ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000513376ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000513376ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000513376ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000513376ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000205214ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000205214ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000205214ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000205214ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000205214ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-3CDSENST00000434343ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-3CDSENST00000434343ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-3CDSENST00000434343ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-3CDSENST00000434343ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
intron-intronENST00000434343ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000451613ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000451613ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000451613ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000451613ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000451613ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000602986ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000602986ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000602986ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
In-frameENST00000602986ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000602986ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000502617ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000502617ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000502617ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
Frame-shiftENST00000502617ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5CDS-intronENST00000502617ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-3CDSENST00000510762ENST00000424120AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-3CDSENST00000510762ENST00000413206AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-3CDSENST00000510762ENST00000503292AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-3CDSENST00000510762ENST00000389652AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000438599AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000511544AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000513811AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000507954AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000515124AASDHchr4

57244314

-CC2D2Achr4

15564978

+
5UTR-intronENST00000510762ENST00000503658AASDHchr4

57244314

-CC2D2Achr4

15564978

+

Top

FusionProtFeatures for AASDH_CC2D2A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AASDH

Q4L235

CC2D2A

Q9P2K1

Component of the tectonic-like complex, a complexlocalized at the transition zone of primary cilia and acting as abarrier that prevents diffusion of transmembrane proteins betweenthe cilia and plasma membranes. Required for ciliogenesis andsonic hedgehog/SHH signaling (By similarity). {ECO:0000250,ECO:0000269|PubMed:18513680}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAASDHchr4:57244314chr4:15564978ENST00000205214-415198_2062221099Nucleotide bindingATP
HgeneAASDHchr4:57244314chr4:15564978ENST00000451613-412198_206222858Nucleotide bindingATP
HgeneAASDHchr4:57244314chr4:15564978ENST00000502617-411198_206222842Nucleotide bindingATP
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+06439_493-85123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+06532_582-85123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+07439_493-33123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+07532_582-33123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+06439_493-69112Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+06532_582-69112Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+06439_493-62123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+06532_582-62123Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+05439_493-55112Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+05532_582-55112Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+20341491_14949551513Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+22371491_149410041621Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+22371491_149410041621Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+061491_1494-85123Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+06221_229-85123Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+06591_596-85123Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+23381491_149410041621Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+071491_1494-33123Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+07221_229-33123Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+07591_596-33123Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+061491_1494-69112Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+06221_229-69112Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+06591_596-69112Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+061491_1494-62123Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+06221_229-62123Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+06591_596-62123Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+051491_1494-55112Compositional biasNote=Poly-Ala
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+05221_229-55112Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+05591_596-55112Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+20341062_11749551513DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+22371062_117410041621DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+22371062_117410041621DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000438599+061062_1174-85123DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+23381062_117410041621DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503658+071062_1174-33123DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000507954+061062_1174-69112DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000511544+061062_1174-62123DomainNote=C2
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000515124+051062_1174-55112DomainNote=C2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAASDHchr4:57244314chr4:15564978ENST00000205214-415553_6302221099DomainCarrier
HgeneAASDHchr4:57244314chr4:15564978ENST00000451613-412553_630222858DomainCarrier
HgeneAASDHchr4:57244314chr4:15564978ENST00000502617-411553_630222842DomainCarrier
HgeneAASDHchr4:57244314chr4:15564978ENST00000513376-314553_630122999DomainCarrier
HgeneAASDHchr4:57244314chr4:15564978ENST00000513376-314198_206122999Nucleotide bindingATP
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+2034439_4939551513Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+2034532_5829551513Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+2237439_49310041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+2237532_58210041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+2237439_49310041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+2237532_58210041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+2338439_49310041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+2338532_58210041621Coiled coilOntology_term=ECO:0000255
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+2034221_2299551513Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000389652+2034591_5969551513Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+2237221_22910041621Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000413206+2237591_59610041621Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+2237221_22910041621Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000424120+2237591_59610041621Compositional biasNote=Poly-Lys
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+2338221_22910041621Compositional biasNote=Poly-Glu
TgeneCC2D2Achr4:57244314chr4:15564978ENST00000503292+2338591_59610041621Compositional biasNote=Poly-Lys


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FusionGeneSequence for AASDH_CC2D2A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_739aa
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSK
FQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVF
INIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFI
TIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYV
SLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFD
TFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWR
PRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPY

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_739aa
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSK
FQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVF
INIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFI
TIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYV
SLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFD
TFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWR
PRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPY

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_739aa
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSK
FQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVF
INIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFI
TIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYV
SLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFD
TFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWR
PRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPY

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_680aa
MKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKH
CLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSK
FQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVF
INIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFIT
RYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAI
PEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPE
ELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEV

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_686aa
MLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRR
KGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTT
TAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKI
DIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISG
KTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWL
LMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGL
SSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLH

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_686aa
MLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRR
KGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTT
TAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKI
DIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISG
KTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWL
LMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGL
SSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLH

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_686aa
MLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRR
KGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTT
TAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKI
DIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISG
KTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWL
LMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGL
SSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLH

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_627aa
MLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRILGLSLFKLAEQKRPLRPRR
KGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTT
TAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARFESQEDE
KLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTS
DQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQ
RYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_2217nt
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGAT
ACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAG
AAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCAT
TGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAG
CATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACA
GCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAA
TTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTAC
CCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCT
AGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTC
ATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGG
CTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTG
GGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATT
ACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAG
TTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGT
TATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTG
TCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCA
GGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCT
GAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGAT
ACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATA
AATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAG
CTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGG
CCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTA
GAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAG
CCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATAC

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_2217nt
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGAT
ACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAG
AAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCAT
TGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAG
CATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACA
GCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAA
TTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTAC
CCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCT
AGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTC
ATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGG
CTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTG
GGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATT
ACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAG
TTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGT
TATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTG
TCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCA
GGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCT
GAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGAT
ACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATA
AATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAG
CTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGG
CCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTA
GAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAG
CCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATAC

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_2217nt
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGAT
ACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAG
AAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCAT
TGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAG
CATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACA
GCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAA
TTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTAC
CCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCT
AGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTC
ATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGG
CTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTG
GGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATT
ACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAG
TTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGT
TATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTG
TCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCA
GGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCT
GAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGAT
ACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATA
AATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAG
CTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGG
CCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTA
GAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAG
CCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATAC

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_2040nt
ATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATTAATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGAT
ACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAG
AAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCAT
TGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAG
CATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACA
GCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAA
TTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTAC
CCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCT
AGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTC
ATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGG
CTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAG
AAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACA
CGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATAT
GTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTG
GCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATT
CCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTT
GATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGG
ATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAA
GAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGG
AGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGAT
GTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTG
AAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_2058nt
ATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACAC
ATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAG
TGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGA
AAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTG
AGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGC
CCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACT
ACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAG
TCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCAT
ACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATA
GATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGC
TCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAA
TTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGA
AAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCA
GAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGAT
CAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTG
TTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGA
CATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGA
TATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTT
TCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAA
GAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAA
AAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCAC
ATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_2058nt
ATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACAC
ATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAG
TGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGA
AAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTG
AGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGC
CCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACT
ACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAG
TCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCAT
ACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATA
GATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGC
TCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAA
TTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGA
AAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCA
GAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGAT
CAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTG
TTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGA
CATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGA
TATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTT
TCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAA
GAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAA
AAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCAC
ATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_2058nt
ATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACAC
ATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAG
TGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGA
AAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTG
AGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGC
CCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACT
ACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAG
TCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCAT
ACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGATTGATGGAACATTTAAAATA
GATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCTGTCCGAAGCTTAAGTGAAGGC
TCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTTGAGTCTCAGGAAGATGAGAAA
TTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGCGGA
AAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACTGCA
GAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCTGAT
CAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTG
TTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGTGGA
CATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAACGA
TATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGCCTT
TCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTAAAA
GAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTAGAA
AAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTTCAC
ATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCTTTA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_1881nt
ATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAATGAAGAAAAAGCAGAAGAACAC
ATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAGATTGTCAGAGTGCCTCATAAG
TGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAGCGACCACTGCGGCCAAGGAGA
AAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTGCGAGCTTACGACATTCCAGTG
AGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCTGCTTCCCCAAGCACGTACAGC
CCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAACGAACAGTTTGCCATACGACT
ACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGATTATAGCACAGCCAGTCTGCAG
TCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGTGAAAGAGGAAGTGGAATCCAT
ACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGGTTTGAGTCTCAGGAAGATGAG
AAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACAACAGTAATTGATATAAGC
GGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCCAATAATCTACAGGCAACT
GCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGTGACCTCTGGAGCACATCT
GATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCTCTGGGTAAGAAGGCCTGG
CTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTAATATGGAATCCCTGCAGT
GGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAATATTTGGTTTAATATTCAA
CGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGAAGCCTTCCATATCCTGGC
CTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGACAGGATTGAAAAAATACTA
AAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGTCACTTCTTGCCTCTGTTA
GAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGGTTCTCTGGATTTCCTCTT
CACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTTCCTAATGTTGAATTTGCT


* Fusion transcript sequences (Full-length transcript).
>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_2481nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAG
CGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTG
CGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCT
GCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAA
CGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGAT
TATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGT
GAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGG
ATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCT
GTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTT
GAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACA
ACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCC
AATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGT
GACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCT
CTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTA
ATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAAT
ATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGA
AGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGAC
AGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGT
CACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGG
TTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTT
CCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCTCTTATACGC
AACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCATCACATCAG

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_2481nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAG
CGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTG
CGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCT
GCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAA
CGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGAT
TATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGT
GAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGG
ATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCT
GTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTT
GAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACA
ACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCC
AATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGT
GACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCT
CTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTA
ATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAAT
ATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGA
AGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGAC
AGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGT
CACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGG
TTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTT
CCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCTCTTATACGC
AACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCATCACATCAG

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_2481nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAG
CGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTG
CGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCT
GCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAA
CGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGAT
TATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGT
GAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGG
ATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGTTTTGATTCT
GTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGAGAAAAGTTT
GAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTTACA
ACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTACCCC
AATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATCTGT
GACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTGTCT
CTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTATTTA
ATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGACAAT
ATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCAAGA
AGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAAGAC
AGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTGCGT
CACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTACAGG
TTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGATGTT
CCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCTCTTATACGC
AACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCATCACATCAG

>In-frame_AASDH_ENST00000513376_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_2293nt
CCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGAGACTTGCTAAAATTCTCCAAGTCCCGGCTGCTTATGTA
CCTATCGAGCCAGATTCACCACCGTCATTATCAACTCATTTTATGAAAAAATGTAATCTAAAGTATATCCTTGTTGAAAAAAAACAAATT
AATAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGACTTCACTGG
AAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAGCATGTCAAT
GAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGGATACCGAAG
ATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCAGAACAAAAG
CGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTGAACATTGTG
CGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAAAAGCATGCT
GCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTCTCTTTTCAA
CGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCTAATGGAGAT
TATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAGGATGACCGT
GAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTCCAAGCAAGG
TTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAGTGCCTT
ACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAATGTCTAC
CCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGTGGTATC
TGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTACTTTCTG
TCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGTCGTTAT
TTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGTCCTGAC
AATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTCTTTTCA
AGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAGCTACAA
GACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCTACTCTG
CGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGAGACTAC
AGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAATATTGAT
GTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCTCTTATA
CGCAACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCATCACAT

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000424120_chr4_15564978_+_2670nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCA
GAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTG
AACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAA
AAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTC
TCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCT
AATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAG
GATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTC
CAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGT
TTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGA
GAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAG
TGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAAT
GTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGT
GGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTAC
TTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGT
CGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGT
CCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTC
TTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAG
CTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCT
ACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGA
GACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAAT
ATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCT
CTTATACGCAACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000413206_chr4_15564978_+_2670nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCA
GAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTG
AACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAA
AAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTC
TCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCT
AATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAG
GATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTC
CAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGT
TTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGA
GAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAG
TGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAAT
GTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGT
GGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTAC
TTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGT
CGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGT
CCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTC
TTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAG
CTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCT
ACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGA
GACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAAT
ATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCT
CTTATACGCAACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000503292_chr4_15564978_+_2670nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCA
GAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTG
AACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAA
AAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTC
TCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCT
AATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAG
GATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTC
CAAGCAAGGATTGATGGAACATTTAAAATAGATATTCCCCCAGTTCTTCTGGGCTACAGTAAGGAGCGAAATATGATTCTTGAGCGGGGT
TTTGATTCTGTCCGAAGCTTAAGTGAAGGCTCCTACATTACCCTCTTTATTACCATTGAGCCCCAGCTGGTTCCTGGAGAGTCCATTCGA
GAAAAGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGTCAG
TGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTTAAT
GTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTTGGT
GGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAATTAC
TTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAAGGT
CGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATAGGT
CCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCTTTC
TTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCTGAG
CTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACCTCT
ACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTGGGA
GACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACATAAT
ATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCCTCT
CTTATACGCAACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATATGCA

>In-frame_AASDH_ENST00000602986_chr4_57244314_-_CC2D2A_ENST00000389652_chr4_15564978_+_2482nt
ACGGCTTCTGGGAGCTGCTGCTTCGCTGTGAGAAGTATCCGCGACGAGCTATCCGGGAAAGGGCCGAATGCGATCAAACCTAATCCGCGA
GACTTGCTAAGGTTCTGTGCTACAAATTGATGTTTAGATAAACTTCAGTGAAATGACTCTTCAGGAATTGGTGCATAAGGCTGCCTCCTG
TTATATGGACAGAGTAGCTGTATGTTTTGATGAATGCAACAACCAGCTTCCAGTTTACTACACCTACAAGACTGTGGTTAATGCTGCTTC
TGAATTATCAAATTTTCTGCTGTTACACTGTGACTTTCAAGGAATTCGGGAAATTGGTCTCTACTGCCAACCTGGGATAGACTTACCCTC
TTGGATTTTAGGAAATTTAAATCTTTTCATGAAACATTATTGAACTATGATACATTTACAGTGGAACATAATGACCTAGTGCTCTTCAGA
CTTCACTGGAAAAATACTGAGGTGAACTTGATGCTAAATGATGGAAAAGAGAAATATGAAAAAGAAAAAATAAAAAGCATAAGTTCTGAG
CATGTCAATGAAGAAAAAGCAGAAGAACACATGGATCTGAGGCTAAAGCATTGCTTAGCCTATGTTCTACATACATCAGGGACTACAGGG
ATACCGAAGATTGTCAGAGTGCCTCATAAGTGTATAGTACCAAATATCCAGCATTTTCGCATTTTGGGCCTAAGCCTTTTCAAGCTGGCA
GAACAAAAGCGACCACTGCGGCCAAGGAGAAAAGGTCGGAAGAAGGTGACAGCCCAAAACCTGTCTGATGGAGACATAAAGCTGCTGGTG
AACATTGTGCGAGCTTACGACATTCCAGTGAGGAAGCCGGCAGTGAGCAAATTCCAGCAGCCGTCGAGGTCTTCAAGGATGTTCAGTGAA
AAGCATGCTGCTTCCCCAAGCACGTACAGCCCAACCCACAATGCTGACTACCCCCTCGGCCAGGTTTTAGTACGTCCCTTTGTAGAAGTC
TCTTTTCAACGAACAGTTTGCCATACGACTACGGCTGAAGGACCAAACCCTAGCTGGAATGAAGAACTAGAACTTCCATTTAGGGCTCCT
AATGGAGATTATAGCACAGCCAGTCTGCAGTCAGTGAAAGATGTTGTGTTCATTAACATTTTTGATGAAGTACTGCATGATGTCTTAGAG
GATGACCGTGAAAGAGGAAGTGGAATCCATACTCGTATTGAGAGACACTGGCTGGGATGTGTGAAAATGCCATTTAGCACAATATATTTC
CAAGCAAGGTTTGAGTCTCAGGAAGATGAGAAATTACTTCAAGCAACTGAGAAGTTTCAAGCTGAATGTGCCTTAAAGTTTCCAAATCGT
CAGTGCCTTACAACAGTAATTGATATAAGCGGAAAAACTGTTTTTATCACACGTTATCTCAAACCTTTAAACCCTCCTCAGGAGCTCCTT
AATGTCTACCCCAATAATCTACAGGCAACTGCAGAACTGGTGGCTCGATATGTGTCCTTGATTCCCTTCTTGCCTGACACTGTCTCATTT
GGTGGTATCTGTGACCTCTGGAGCACATCTGATCAATTTCTTGATCTCCTGGCAGGGGATGAAGAAGAACATGCAGTACTATTGTGTAAT
TACTTTCTGTCTCTGGGTAAGAAGGCCTGGCTGTTGATGGGCAATGCTATTCCTGAGGGTCCAACTGCCTATGTGCTAACTTGGGAGCAA
GGTCGTTATTTAATATGGAATCCCTGCAGTGGACATTTTTATGGACAATTTGATACATTCTGTCCCTTGAAAAATGTGGGCTGTTTAATA
GGTCCTGACAATATTTGGTTTAATATTCAACGATATGAATCTCCACTAAGGATAAATTTTGATGTCACCAGGCCCAAGCTATGGAAATCT
TTCTTTTCAAGAAGCCTTCCATATCCTGGCCTTTCCAGTGTTCAGCCTGAAGAGCTAATTTACCAGCGCTCAGACAAAGCAGCTGCAGCT
GAGCTACAAGACAGGATTGAAAAAATACTAAAAGAAAAAATCATGGACTGGAGGCCACGCCATCTGACTCGGTGGAATAGGTATTGTACC
TCTACTCTGCGTCACTTCTTGCCTCTGTTAGAAAAAAGTCAAGGAGAAGATGTAGAAGATGACCACAGAGCAGAACTGCTAAAACAGCTG
GGAGACTACAGGTTCTCTGGATTTCCTCTTCACATGCCTTATTCTGAAGTGAAGCCTTTAATTGACGCTGTGTATAGTACTGGAGTACAT
AATATTGATGTTCCTAATGTTGAATTTGCTTTAGCTGTATACATACACCCATACCCCAAAAATGTTTTGTCTGTTTGGATCTATGTTGCC
TCTCTTATACGCAACAGGTAATTTTTTTCACTGTACTTTCTGTATCATGTAAAAACTACACTTAGGATATGAGAAAATTTTAAATTATAT


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FusionGenePPI for AASDH_CC2D2A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
AASDHGPSM2, EGFR, RNF113A, GORASP1, TKTCC2D2AOFD1, PCM1, AHI1, ASCC2, ASCC3, CEP131, B9D1, B9D2, DVL3, ECH1, GPATCH1, HAUS8, LMNA, MB21D2, MKS1, NOLC1, NOP2, RPF2, SRP72, SRP9, STAMBPL1, STAU1, TCTN3, TDRD3, TRIM26, UNC45A, WDR55, WDR83, XRN1, YTHDC2, YWHAH, ZC3H15, CCDC138, SSX2IP, NHP2L1, TCTN1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for AASDH_CC2D2A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for AASDH_CC2D2A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneCC2D2AC2676788JOUBERT SYNDROME 9 (disorder)8CTD_human;UNIPROT
TgeneCC2D2AC1857662COACH syndrome2CTD_human;ORPHANET;UNIPROT
TgeneCC2D2AC2676790MECKEL SYNDROME, TYPE 6 (disorder)2CTD_human;UNIPROT