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Fusion gene ID: 5501 |
FusionGeneSummary for CAPS_CCNG2 |
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Fusion gene information | Fusion gene name: CAPS_CCNG2 | Fusion gene ID: 5501 | Hgene | Tgene | Gene symbol | CAPS | CCNG2 | Gene ID | 8618 | 901 |
Gene name | calcium dependent secretion activator | cyclin G2 | |
Synonyms | CADPS1|CAPS|CAPS1|UNC-31 | - | |
Cytomap | 3p14.2 | 4q21.1 | |
Type of gene | protein-coding | protein-coding | |
Description | calcium-dependent secretion activator 1CAPS-1Ca++-dependent secretion activatorCa2+ dependent secretion activatorCa2+-dependent activator protein for secretionCa2+-regulated cytoskeletal proteincalcium-dependent activator protein for secretion 1 | cyclin-G2 | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q13938 | Q16589 | |
Ensembl transtripts involved in fusion gene | ENST00000588776, ENST00000222125, ENST00000452990, | ENST00000497512, ENST00000316355, ENST00000354403, ENST00000502280, ENST00000395640, ENST00000509972, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 2 X 2=12 |
# samples | 1 | 3 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: CAPS [Title/Abstract] AND CCNG2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AA570323 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3UTR | ENST00000588776 | ENST00000497512 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000588776 | ENST00000316355 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000588776 | ENST00000354403 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000588776 | ENST00000502280 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000588776 | ENST00000395640 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000588776 | ENST00000509972 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000497512 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000316355 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000354403 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000502280 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000395640 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000222125 | ENST00000509972 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000497512 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000316355 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000354403 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000502280 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000395640 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
intron-3UTR | ENST00000452990 | ENST00000509972 | CAPS | chr19 | 5916529 | + | CCNG2 | chr4 | 78079780 | - |
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FusionProtFeatures for CAPS_CCNG2 |
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Hgene | Tgene |
CAPS | CCNG2 |
Calcium-binding protein. May play a role in cellularsignaling events (Potential). {ECO:0000305}. | May play a role in growth regulation and in negativeregulation of cell cycle progression. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CAPS_CCNG2 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for CAPS_CCNG2 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CAPS_CCNG2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Hgene | CAPS | Q13938 | DB11093 | Calcium Citrate | Calcyphosin | small molecule | approved |
Hgene | CAPS | Q13938 | DB11348 | Calcium Phosphate | Calcyphosin | small molecule | approved |
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RelatedDiseases for CAPS_CCNG2 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |