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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 5425

FusionGeneSummary for CANX_CCT4

check button Fusion gene summary
Fusion gene informationFusion gene name: CANX_CCT4
Fusion gene ID: 5425
HgeneTgene
Gene symbol

CANX

CCT4

Gene ID

821

10575

Gene namecalnexinchaperonin containing TCP1 subunit 4
SynonymsCNX|IP90|P90CCT-DELTA|Cctd|SRB
Cytomap

5q35.3

2p15

Type of geneprotein-codingprotein-coding
Descriptioncalnexinmajor histocompatibility complex class I antigen-binding protein p88T-complex protein 1 subunit deltaTCP-1-deltachaperonin containing TCP1, subunit 4 (delta)chaperonin containing t-complex polypeptide 1, delta subunitstimulator of TAR RNA-binding
Modification date2018052220180523
UniProtAcc

P27824

P50991

Ensembl transtripts involved in fusion geneENST00000504734, ENST00000415618, 
ENST00000452673, ENST00000247461, 
ENST00000512607, ENST00000503126, 
ENST00000394440, ENST00000461540, 
ENST00000544079, ENST00000544185, 
ENST00000538252, 
Fusion gene scores* DoF score9 X 11 X 4=3965 X 6 X 4=120
# samples 126
** MAII scorelog2(12/396*10)=-1.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CANX [Title/Abstract] AND CCT4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUSCTCGA-66-2795-01ACANXchr5

179136060

+CCT4chr2

62099723

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000504734ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000504734ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000504734ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000504734ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000504734ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-
In-frameENST00000415618ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000415618ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000415618ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000415618ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000415618ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-
In-frameENST00000452673ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000452673ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000452673ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000452673ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000452673ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-
In-frameENST00000247461ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000247461ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000247461ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000247461ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000247461ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-
In-frameENST00000512607ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000512607ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000512607ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000512607ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
5CDS-intronENST00000512607ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-
3UTR-3CDSENST00000503126ENST00000394440CANXchr5

179136060

+CCT4chr2

62099723

-
3UTR-intronENST00000503126ENST00000461540CANXchr5

179136060

+CCT4chr2

62099723

-
3UTR-intronENST00000503126ENST00000544079CANXchr5

179136060

+CCT4chr2

62099723

-
3UTR-intronENST00000503126ENST00000544185CANXchr5

179136060

+CCT4chr2

62099723

-
3UTR-intronENST00000503126ENST00000538252CANXchr5

179136060

+CCT4chr2

62099723

-

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FusionProtFeatures for CANX_CCT4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CANX

P27824

CCT4

P50991

Calcium-binding protein that interacts with newlysynthesized glycoproteins in the endoplasmic reticulum. It may actin assisting protein assembly and/or in the retention within theER of unassembled protein subunits. It seems to play a major rolein the quality control apparatus of the ER by the retention ofincorrectly folded proteins. Associated with partial T-cellantigen receptor complexes that escape the ER of immaturethymocytes, it may function as a signaling complex regulatingthymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. Molecular chaperone; assists the folding of proteinsupon ATP hydrolysis. As part of the BBS/CCT complex may play arole in the assembly of BBSome, a complex involved in ciliogenesisregulating transports vesicles to the cilia. Known to play a role,in vitro, in the folding of actin and tubulin.{ECO:0000269|PubMed:20080638}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615276_409176593RegionP domain (Extended arm)
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615278_345176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615348_405176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615276_409176593RegionP domain (Extended arm)
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615278_345176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615348_405176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615276_409176593RegionP domain (Extended arm)
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615278_345176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615348_405176593RegionNote=4 X approximate repeats
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615278_290176593RepeatNote=1-1
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615295_307176593RepeatNote=1-2
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615314_326176593RepeatNote=1-3
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615333_345176593RepeatNote=1-4
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615348_358176593RepeatNote=2-1
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615367_377176593RepeatNote=2-2
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615381_391176593RepeatNote=2-3
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615395_405176593RepeatNote=2-4
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615278_290176593RepeatNote=1-1
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615295_307176593RepeatNote=1-2
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615314_326176593RepeatNote=1-3
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615333_345176593RepeatNote=1-4
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615348_358176593RepeatNote=2-1
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615367_377176593RepeatNote=2-2
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615381_391176593RepeatNote=2-3
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615395_405176593RepeatNote=2-4
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615278_290176593RepeatNote=1-1
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615295_307176593RepeatNote=1-2
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615314_326176593RepeatNote=1-3
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615333_345176593RepeatNote=1-4
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615348_358176593RepeatNote=2-1
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615367_377176593RepeatNote=2-2
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615381_391176593RepeatNote=2-3
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615395_405176593RepeatNote=2-4
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+61521_481176593Topological domainLumenal
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+61521_481176593Topological domainLumenal
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+61521_481176593Topological domainLumenal
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615482_502176593TransmembraneHelical
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615482_502176593TransmembraneHelical
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615482_502176593TransmembraneHelical


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FusionGeneSequence for CANX_CCT4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CANX_ENST00000504734_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_341aa
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLITGC
ASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENA

>In-frame_CANX_ENST00000415618_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_376aa
MADRRTPTPFAGCRLPRQRRARDASQVSAPGTRRIMEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSS
PKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKP
LIVQYEVNFQNGIECGGAYVKLLSKTPELNLITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELAL
RLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATE

>In-frame_CANX_ENST00000452673_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_341aa
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLITGC
ASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENA

>In-frame_CANX_ENST00000247461_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_341aa
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLITGC
ASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENA

>In-frame_CANX_ENST00000512607_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_233aa
MKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLITGCASPGKTVTIVVRGSNKLV
IEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQG


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CANX_ENST00000504734_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1023nt
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTT
GTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTAT
GAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGT
GCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTA
TGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATAT
TCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCC
GGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGT
ATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATT

>In-frame_CANX_ENST00000415618_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1128nt
ATGGCCGATCGTCGGACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCA
GGAACCAGACGGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGAT
GATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCT
CCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTA
TCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCA
GGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCT
CTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAAC
CTGATTACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCC
ATTCATGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTA
CGATTAACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACA
CTAGCTGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAAT
GTCCGAAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAA

>In-frame_CANX_ENST00000452673_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1023nt
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTT
GTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTAT
GAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGT
GCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTA
TGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATAT
TCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCC
GGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGT
ATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATT

>In-frame_CANX_ENST00000247461_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1023nt
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTT
GTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTAT
GAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGT
GCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTA
TGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATAT
TCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCC
GGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGT
ATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATT

>In-frame_CANX_ENST00000512607_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_699nt
ATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCC
TTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTT
TCTAAAACACCAGAACTCAACCTGATTACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTG
ATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCT
CCAGAAATAGAGTTGGCCCTACGATTAACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCT
ATGGAGGTCATTCCATCTACACTAGCTGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGA
GAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGT


* Fusion transcript sequences (Full-length transcript).
>In-frame_CANX_ENST00000504734_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1816nt
AGTGCACGCCAATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGC
CGATCGTCGGACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAAC
CAGACGGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGA
TGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAA
GGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAA
AGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGA
TAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCAT
TGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGAT
TACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCA
TGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATT
AACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGC
TGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCG
AAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGT
TCGGAGCATTCTGAAAATAGATGATGTGGTAAACACTCGATAATCTGGATAACTGACTAGCACCATTATGATCACCAGTATTGTGGCTGG
AATGGAAGAAGATCACCTTGGTGTTCCTTGTTTGGAAGATTATTTCCTCTGAATTTCTGGGCTTGGTCTTCCAGTTGGCATTTGCCTGAA
GTTGTATTGAAACAATTTAATGAAAATATTAAATATTTGGTTTCAAAAGGCAGATTTATCTTCTCCCAACATTCTGTTATTTCTGATACT
TTTGAAAAACTAATAAAAACTAATAAAAGAAGCGTAAAAAGTGAGTTTACATGTTGAGGAAAAAAATGGCCCAATATGCTCATCACTGAT
AAATGCTCCCTGGCCTTAAAAACTACCAACATATAATATATATGCTGTCTTAAAAGTTAATGATCCAAGTGGCACCTCTCTGAACCTACT
TTGGCTTGGGAGGCTGCCCAGTTAAAACAAAAATAAGTTAATGGTACAGAAAGAGAATGAAAAATGAAAGCCTCCTTTTATCCTATCATC
CTAATTCCTTTTCCCAGTAATAATGACTGCTGTGTTGGATTCCTTCTGCAAATAAAAGTGTATACATATATGTAGCAAATCTTACTTAAA

>In-frame_CANX_ENST00000415618_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1806nt
AATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGCCGATCGTCGG
ACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAACCAGACGGATC
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTT
GTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTAT
GAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGT
GCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTA
TGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATAT
TCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCC
GGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGT
ATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATT
CTGAAAATAGATGATGTGGTAAACACTCGATAATCTGGATAACTGACTAGCACCATTATGATCACCAGTATTGTGGCTGGAATGGAAGAA
GATCACCTTGGTGTTCCTTGTTTGGAAGATTATTTCCTCTGAATTTCTGGGCTTGGTCTTCCAGTTGGCATTTGCCTGAAGTTGTATTGA
AACAATTTAATGAAAATATTAAATATTTGGTTTCAAAAGGCAGATTTATCTTCTCCCAACATTCTGTTATTTCTGATACTTTTGAAAAAC
TAATAAAAACTAATAAAAGAAGCGTAAAAAGTGAGTTTACATGTTGAGGAAAAAAATGGCCCAATATGCTCATCACTGATAAATGCTCCC
TGGCCTTAAAAACTACCAACATATAATATATATGCTGTCTTAAAAGTTAATGATCCAAGTGGCACCTCTCTGAACCTACTTTGGCTTGGG
AGGCTGCCCAGTTAAAACAAAAATAAGTTAATGGTACAGAAAGAGAATGAAAAATGAAAGCCTCCTTTTATCCTATCATCCTAATTCCTT
TTCCCAGTAATAATGACTGCTGTGTTGGATTCCTTCTGCAAATAAAAGTGTATACATATATGTAGCAAATCTTACTTAAACAAAAGGGTT

>In-frame_CANX_ENST00000452673_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1773nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTG
GTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAG
GTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTT
GCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGAT
GGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATC
TCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGT
GGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTGTT
CGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCT
CTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACTGC
GTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAACTA
AGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCCAG
CCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATTCTGAAAATAGATGATGTGGTAAACACTCGATAA
TCTGGATAACTGACTAGCACCATTATGATCACCAGTATTGTGGCTGGAATGGAAGAAGATCACCTTGGTGTTCCTTGTTTGGAAGATTAT
TTCCTCTGAATTTCTGGGCTTGGTCTTCCAGTTGGCATTTGCCTGAAGTTGTATTGAAACAATTTAATGAAAATATTAAATATTTGGTTT
CAAAAGGCAGATTTATCTTCTCCCAACATTCTGTTATTTCTGATACTTTTGAAAAACTAATAAAAACTAATAAAAGAAGCGTAAAAAGTG
AGTTTACATGTTGAGGAAAAAAATGGCCCAATATGCTCATCACTGATAAATGCTCCCTGGCCTTAAAAACTACCAACATATAATATATAT
GCTGTCTTAAAAGTTAATGATCCAAGTGGCACCTCTCTGAACCTACTTTGGCTTGGGAGGCTGCCCAGTTAAAACAAAAATAAGTTAATG
GTACAGAAAGAGAATGAAAAATGAAAGCCTCCTTTTATCCTATCATCCTAATTCCTTTTCCCAGTAATAATGACTGCTGTGTTGGATTCC

>In-frame_CANX_ENST00000247461_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1826nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGGGCACGGGCACCCCCGCGG
TCCCCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGAC
ATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTT
CATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGA
TTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGC
TTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCA
AGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAAC
TCAACCTGATTACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTGTTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGC
GCTCCATTCATGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGGCTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGG
CCCTACGATTAACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACTGCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCAT
CTACACTAGCTGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAACTAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCA
TTAATGTCCGAAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCCAGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAA
CTGAAACTGTTCGGAGCATTCTGAAAATAGATGATGTGGTAAACACTCGATAATCTGGATAACTGACTAGCACCATTATGATCACCAGTA
TTGTGGCTGGAATGGAAGAAGATCACCTTGGTGTTCCTTGTTTGGAAGATTATTTCCTCTGAATTTCTGGGCTTGGTCTTCCAGTTGGCA
TTTGCCTGAAGTTGTATTGAAACAATTTAATGAAAATATTAAATATTTGGTTTCAAAAGGCAGATTTATCTTCTCCCAACATTCTGTTAT
TTCTGATACTTTTGAAAAACTAATAAAAACTAATAAAAGAAGCGTAAAAAGTGAGTTTACATGTTGAGGAAAAAAATGGCCCAATATGCT
CATCACTGATAAATGCTCCCTGGCCTTAAAAACTACCAACATATAATATATATGCTGTCTTAAAAGTTAATGATCCAAGTGGCACCTCTC
TGAACCTACTTTGGCTTGGGAGGCTGCCCAGTTAAAACAAAAATAAGTTAATGGTACAGAAAGAGAATGAAAAATGAAAGCCTCCTTTTA
TCCTATCATCCTAATTCCTTTTCCCAGTAATAATGACTGCTGTGTTGGATTCCTTCTGCAAATAAAAGTGTATACATATATGTAGCAAAT

>In-frame_CANX_ENST00000512607_chr5_179136060_+_CCT4_ENST00000394440_chr2_62099723_-_1685nt
GTTCTGCGGCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGGGCACGGGCAC
CCCCGCGGTCCCCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCA
TGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGC
TCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTC
AGGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCA
TCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTG
GTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGATTACAGGCTGTGCCAGCCCTGGAAAAACAGTTACAATTGTTG
TTCGTGGTTCTAACAAACTGGTGATTGAAGAAGCTGAGCGCTCCATTCATGATGCCCTATGTGTTATTCGTTGTTTAGTGAAGAAGAGGG
CTCTTATTGCAGGAGGTGGTGCTCCAGAAATAGAGTTGGCCCTACGATTAACTGAATATTCACGAACACTGAGTGGTATGGAATCCTACT
GCGTTCGTGCTTTTGCAGATGCTATGGAGGTCATTCCATCTACACTAGCTGAAAATGCCGGCCTGAATCCCATTTCTACAGTAACAGAAC
TAAGAAACCGGCATGCCCAGGGAGAAAAAACTGCAGGCATTAATGTCCGAAAGGGTGGTATTTCCAACATTTTGGAGGAACTGGTTGTCC
AGCCTCTGTTGGTATCAGTCAGTGCTCTGACTCTTGCAACTGAAACTGTTCGGAGCATTCTGAAAATAGATGATGTGGTAAACACTCGAT
AATCTGGATAACTGACTAGCACCATTATGATCACCAGTATTGTGGCTGGAATGGAAGAAGATCACCTTGGTGTTCCTTGTTTGGAAGATT
ATTTCCTCTGAATTTCTGGGCTTGGTCTTCCAGTTGGCATTTGCCTGAAGTTGTATTGAAACAATTTAATGAAAATATTAAATATTTGGT
TTCAAAAGGCAGATTTATCTTCTCCCAACATTCTGTTATTTCTGATACTTTTGAAAAACTAATAAAAACTAATAAAAGAAGCGTAAAAAG
TGAGTTTACATGTTGAGGAAAAAAATGGCCCAATATGCTCATCACTGATAAATGCTCCCTGGCCTTAAAAACTACCAACATATAATATAT
ATGCTGTCTTAAAAGTTAATGATCCAAGTGGCACCTCTCTGAACCTACTTTGGCTTGGGAGGCTGCCCAGTTAAAACAAAAATAAGTTAA
TGGTACAGAAAGAGAATGAAAAATGAAAGCCTCCTTTTATCCTATCATCCTAATTCCTTTTCCCAGTAATAATGACTGCTGTGTTGGATT


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FusionGenePPI for CANX_CCT4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CANXLRP1, APOB, EDEM1, PIGK, LCT, CALR, CD1D, EBI3, CD3D, ITGB1, F8, TF, SLC6A4, TSHR, SLC2A1, SLC4A1, LPA, SVIP, BSCL2, ZNRF4, HDAC5, AMFR, L1CAM, NDRG1, ELAVL1, SIRT7, TCF3, UBXN4, CUL3, CAND1, POMP, LMAN1, OPRD1, CHRNA5, CFTR, SERPINF2, KCNH2, BCAP31, UBXN6, TOR1A, PRKCSH, GANAB, RPN2, ASGR1, VCP, PKD2, LDLR, SERPINA1, CSNK2A1, PGRMC1, ATF2, MTNR1A, SMURF2, UBL4A, YIPF3, CLN5, PDIA3, ADRB2, PTGIR, FBXO6, RPA3, RPA2, RPA1, WWOX, NPHS1, LGR4, STAU1, HUWE1, ERLIN2, TRAF6, PMP22, CUL7, CCDC8, SUZ12, RNF2, BMI1, EGFR, FOXRED2, EMC1, PPT1, FAM187B, OGFOD3, POMK, POGLUT1, WNT3A, CHST8, PLTP, CHST9, HNRNPA1, ABCC1, ABCC3, ATP13A1, ACADM, APMAP, ATL3, ATP1B1, ATP2B1, ATP2B3, ATP2B4, CCT4, DARS, DDOST, DNAJA1, EPRS, HSP90AA1, KPNA3, KPNA4, PDIA6, PPP2R1A, PTBP1, RAB2A, RPN1, RPS5, SEC61B, SLC25A3, TECR, CCT3, CCT6A, CLTC, COPB1, CYC1, ETFA, HSP90B1, IDH3A, IPO9, KDSR, KPNA2, MOGS, COX2, NCLN, PC, PSMC2, RAB1A, RAB1B, RCN1, SPTAN1, TUFM, UQCRC2, NTRK1, EWSR1, MDM2, TCTN2, TCTN3, TCTN1, CLU, GBA, LNPEP, ATXN3, SLC33A1, CHST15, RFWD3, CHMP4B, EDEM2, ERBB3, ESRRB, GABRA1, U2AF2, GGT1, TMEM258, CDC73, DERL1, PTPRN, ACP5, CD1E, P2RX2, CLEC2D, BRINP2, GXYLT1, NRROS, CHST6, TMEM5, LIPG, HYAL3, ADAM21, UST, CD1B, DPEP3, DNASE2, GABRG2, ADAM30, P2RX5, TMPRSS11B, AMIGO3, IL27RA, MPPE1, CPA5, DCT, ST3GAL2, WNT16, OPCML, GAL3ST1, FUCA2, C12orf49, NCEH1, SMPD1, B3GNT3, CCNJL, AGT, ARSG, FUT9, TOR3A, A4GALT, IGSF6, TRHDE, GPR114, TMPRSS3, SERPINA5, SCNN1D, CHST14, TMED6, WNT7A, ST8SIA3, PTPRA, PTPRE, PTPRO, MTNR1B, COX15, DLST, SDHA, SOAT1, VDAC1, EDEM3, TAP1, TRIM25, RNF185, GRIN1CCT4PPP4C, PPP2CA, STK24, STRN, STRN3, PPP2CB, PPP2R2C, IGBP1, TCP1, ACTA2, ACTA1, MEPCE, HNRNPH1, GPN1, CDK9, RFWD2, MYC, PPP2R2A, PPP2R2B, PPP2R2D, PPP2R4, HDAC5, PSMA3, RPS6KA1, PCK1, VHL, ISG15, FBXO25, CUL3, CUL5, CDK2, CUL1, COPS5, GRB2, PACRG, CCT2, CCT6A, CCT3, CCT7, CCT5, CCT8, CCT6B, RPSA, P4HB, PSMA6, SSR1, G6PD, XPO1, TXNL1, SMURF1, VCP, CFAP52, FN1, VCAM1, ATF2, PEX14, PPP5C, NOS2, FAM86B2, METTL18, METTL21B, ITGA4, CFTR, PAN2, CD81, IGSF8, ICAM1, HDAC3, HDAC11, FBXW4, FBXO6, PRPF40A, USP9X, VARS, VRK2, CDK5, ILK, UBC, STAU1, CDC20, LGALS3BP, NEDD1, TP53, TUBG1, HUWE1, FUS, CUL7, IKBKE, IRAK1, JAK3, MAPK8, PTK6, SGK2, TSSK6, TYK2, WDR76, POC1A, TXNDC9, WDR83, PEX7, ACTR1B, SEC31B, ACTL6A, TTLL3, CDK15, RPS6KB2, DCAF7, AMBRA1, UNK, CANX, CAD, DNAJA2, EHD2, MCM7, SLC25A3, DNAJA4, HSPE1, KIAA0368, PDCL3, PSMC2, NTRK1, BTRC, B9D1, MKS1, CETN2, AHSA1, CDK1, DDB2, HDAC1, PDK3, NSMAF, NIPSNAP1, PRPF4, BUB3, ACTR2, FGFR1OP2, WRAP53, RFWD3, KIF21A, MYO19, SEH1L, TUBA1C, ARMC6, GAN, CRY1, CRY2, ALKBH3, MCM2, SNW1, CDC5L, TTC27, NLE1, CDC73, ZNF746, FLCN, PPM1J, KLHL33, KLHDC8A, KDM4B, ACTR3B, RAP2C, WDR86, THOC3, DCAF11, DCAF10, DCAF8, WDR77, TUBG2, WDTC1, WDR5B, HCFC2, TBL1Y, PDDC1, WDR34, DNAI2, PNPLA5, WDR37, POC1B, GNB2, TUBA1B, ODF1, ACTBL2, CDK11A, ACTR3, ASTN2, GANAB, RBM3, CYLD, WDR92, TRIM25, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCANXchr5:179136060chr2:62099723ENST00000247461+615326_359176593PPIB
HgeneCANXchr5:179136060chr2:62099723ENST00000452673+615326_359176593PPIB
HgeneCANXchr5:179136060chr2:62099723ENST00000504734+615326_359176593PPIB


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CANX_CCT4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneCANXP27824DB00031TenecteplaseCalnexinbiotechapproved
HgeneCANXP27824DB11093Calcium CitrateCalnexinsmall moleculeapproved
HgeneCANXP27824DB11348Calcium PhosphateCalnexinsmall moleculeapproved
HgeneCANXP27824DB00025Antihemophilic factor, human recombinantCalnexinbiotechapproved|investigational

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RelatedDiseases for CANX_CCT4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCANXC0151744Myocardial Ischemia1CTD_human