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Fusion gene ID: 5081 |
FusionGeneSummary for C7orf31_RARS2 |
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Fusion gene information | Fusion gene name: C7orf31_RARS2 | Fusion gene ID: 5081 | Hgene | Tgene | Gene symbol | C7orf31 | RARS2 | Gene ID | 136895 | 57038 |
Gene name | chromosome 7 open reading frame 31 | arginyl-tRNA synthetase 2, mitochondrial | |
Synonyms | - | ArgRS|DALRD2|PCH6|PRO1992|RARSL | |
Cytomap | 7p15.3 | 6q15 | |
Type of gene | protein-coding | protein-coding | |
Description | uncharacterized protein C7orf31 | probable arginine--tRNA ligase, mitochondrialprobable arginyl-tRNA synthetase, mitochondrial | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q8N865 | Q5T160 | |
Ensembl transtripts involved in fusion gene | ENST00000409280, ENST00000283905, | ENST00000369536, ENST00000497828, | |
Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 3 X 3 X 1=9 |
# samples | 2 | 4 | |
** MAII score | log2(2/8*10)=1.32192809488736 | log2(4/9*10)=2.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: C7orf31 [Title/Abstract] AND RARS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | DA751840 | C7orf31 | chr7 | 25219590 | - | RARS2 | chr6 | 88279310 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000409280 | ENST00000369536 | C7orf31 | chr7 | 25219590 | - | RARS2 | chr6 | 88279310 | - |
intron-intron | ENST00000409280 | ENST00000497828 | C7orf31 | chr7 | 25219590 | - | RARS2 | chr6 | 88279310 | - |
intron-3CDS | ENST00000283905 | ENST00000369536 | C7orf31 | chr7 | 25219590 | - | RARS2 | chr6 | 88279310 | - |
intron-intron | ENST00000283905 | ENST00000497828 | C7orf31 | chr7 | 25219590 | - | RARS2 | chr6 | 88279310 | - |
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FusionProtFeatures for C7orf31_RARS2 |
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Hgene | Tgene |
C7orf31 | RARS2 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for C7orf31_RARS2 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for C7orf31_RARS2 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for C7orf31_RARS2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for C7orf31_RARS2 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |