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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 4994

FusionGeneSummary for C3orf58_SLC9A9

check button Fusion gene summary
Fusion gene informationFusion gene name: C3orf58_SLC9A9
Fusion gene ID: 4994
HgeneTgene
Gene symbol

C3orf58

SLC9A9

Gene ID

205428

285195

Gene namechromosome 3 open reading frame 58solute carrier family 9 member A9
SynonymsDIA1|GoPro49|HASFAUTS16|NHE9
Cytomap

3q24

3q24

Type of geneprotein-codingprotein-coding
Descriptiondeleted in autism protein 1Golgi Protein of 49 kDaGolgi protein GoPro49UPF0672 protein C3orf58deleted in autism 1hypoxia and AKT-induced stem cell factorhypoxia and Akt induced stem cell factorsodium/hydrogen exchanger 9Na(+)/H(+) exchanger 9putative protein product of Nbla00118sodium/proton exchanger NHE9solute carrier family 9 (sodium/hydrogen exchanger)solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
Modification date2018052320180523
UniProtAcc

Q8NDZ4

Q8IVB4

Ensembl transtripts involved in fusion geneENST00000315691, ENST00000493396, 
ENST00000495414, ENST00000441925, 
ENST00000316549, ENST00000498717, 
Fusion gene scores* DoF score1 X 1 X 1=17 X 7 X 5=245
# samples 17
** MAII scorelog2(1/1*10)=3.32192809488736log2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C3orf58 [Title/Abstract] AND SLC9A9 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneC3orf58

GO:0014066

regulation of phosphatidylinositol 3-kinase signaling

23784961

HgeneC3orf58

GO:0060038

cardiac muscle cell proliferation

23784961


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDCOADTCGA-A6-2674-01AC3orf58chr3

143691831

+SLC9A9chr3

143515745

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000315691ENST00000316549C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
5CDS-intronENST00000315691ENST00000498717C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
3UTR-3CDSENST00000493396ENST00000316549C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
3UTR-intronENST00000493396ENST00000498717C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
intron-3CDSENST00000495414ENST00000316549C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
intron-intronENST00000495414ENST00000498717C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
intron-3CDSENST00000441925ENST00000316549C3orf58chr3

143691831

+SLC9A9chr3

143515745

-
intron-intronENST00000441925ENST00000498717C3orf58chr3

143691831

+SLC9A9chr3

143515745

-

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FusionProtFeatures for C3orf58_SLC9A9


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
C3orf58

Q8NDZ4

SLC9A9

Q8IVB4

May play a role in cardiomyocyte proliferation throughparacrine signaling and activation of the PPI3K-AKT-CDK7 signalingcascade. {ECO:0000269|PubMed:23784961}. May act in electroneutral exchange of protons for Na(+)across membranes. Involved in the effusion of Golgi luminal H(+)in exchange for cytosolic cations. Involved in organelle ionhomeostasis by contributing to the maintenance of the uniqueacidic pH values of the Golgi and post-Golgi compartments in thecell. {ECO:0000269|PubMed:15522866}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116127_147126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116165_185126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116204_224126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116236_256126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116278_298126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116302_322126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116323_343126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116365_385126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116387_407126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116430_450126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-116466_486126646TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-11621_41126646TransmembraneHelical
TgeneSLC9A9chr3:143691831chr3:143515745ENST00000316549-11646_66126646TransmembraneHelical


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FusionGeneSequence for C3orf58_SLC9A9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_C3orf58_ENST00000315691_chr3_143691831_+_SLC9A9_ENST00000316549_chr3_143515745_-_739aa
MWRLVPPKLGRLSRSLKLAALGSLLVLMVLHSPSLLASWQRNELTDRRFLQLNKCPACFGTSWCRRFLNGQVVFEAWGRLRLLDFLNVKN
VYFAQYGEPREGGRRRVVLKRLGSQRELAQLDQSICKRATGRPRCDLLQAMPRTEFARLNGDVRLLTPEAVEGWSDLVHCPSQRLLDRLV
RRYAETKDSGSFLLRNLKDSERMQLLLTLAFNPEPLVLQMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVI
GLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFD
AAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDS
KIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFA
LAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYL
KPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLGLDQKASPQTPGKENIYEGDLG


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_C3orf58_ENST00000315691_chr3_143691831_+_SLC9A9_ENST00000316549_chr3_143515745_-_2217nt
ATGTGGCGCCTGGTGCCCCCGAAGCTGGGCCGCCTGTCCCGCTCGCTGAAGCTGGCGGCGCTGGGCAGCCTGTTGGTGCTGATGGTGCTG
CACTCGCCGTCGCTGCTCGCCTCTTGGCAGCGCAACGAACTGACCGACCGGCGCTTCCTGCAGCTCAATAAGTGCCCGGCGTGCTTCGGC
ACGAGCTGGTGCCGCCGCTTCCTCAACGGGCAGGTGGTATTCGAGGCGTGGGGCCGCTTGCGCCTGCTGGACTTCCTCAACGTGAAGAAC
GTGTACTTCGCGCAGTACGGCGAGCCCCGCGAGGGCGGCCGCCGCCGAGTGGTGCTCAAGCGCCTCGGCTCGCAGCGCGAGCTGGCGCAG
CTCGACCAGAGCATCTGCAAGCGGGCCACCGGCCGGCCCCGCTGCGACCTGCTGCAGGCCATGCCCCGGACCGAGTTCGCGCGCCTCAAC
GGCGACGTGCGTCTGCTCACGCCCGAGGCGGTGGAGGGCTGGTCGGACCTGGTGCACTGCCCCTCGCAGCGCCTTCTCGACCGCCTGGTG
CGCCGCTACGCGGAGACCAAGGACTCGGGCAGCTTCCTGCTTCGCAACCTCAAGGACTCGGAGCGCATGCAGCTGCTGCTGACCCTGGCC
TTCAACCCCGAGCCGCTGGTGCTACAGATGACATTTGATCCAGAAATCTTCTTCAATGTTTTACTGCCACCAATTATATTTCATGCAGGA
TATAGTCTAAAGAAGAGACACTTTTTTCAAAACTTAGGATCTATTTTAACGTATGCCTTCTTGGGAACTGCCATCTCCTGCATCGTCATA
GGGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTT
GGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTT
GGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGAT
GCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCA
CTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCC
GAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCC
AAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTC
CAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTC
CTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCC
TTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGA
GGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACAC
CAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTG
AAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAA
GCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCA
CCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_C3orf58_ENST00000315691_chr3_143691831_+_SLC9A9_ENST00000316549_chr3_143515745_-_4232nt
CTTGGTCTCAGGAGAGCCAGCGCGCACAAGCAAGGGTGTGCGGCTCTGAGACGTGCGTTGCTGCTTGTGGGTGTGAGACATCCTAGCTCC
TCTTCCCCTTCCGTGAGTCCCTCCTTTCCTCGCAGACCCCACTTGTCGTGGCTGGCTGCCGCCGCAGCTCTTGTGCGAAGCCAGCAGTGC
GCGTGCGCGCGGGCACGGGCGCGCGACCGTCGGGTCCCCGCGCTCCCTCCCCCTCCCGCTCCTCTATAACTTGGCTGGCGTGGAGGAGGC
GCCGCCGGAGTCGGAGGGCGGGGAGCTAGGAGGAGGGAGCTCGAGAGTTGTGGAGACTAGTGACTGGGAGAAGTCGCAGCCCGCTCAGGC
CCGCGCCTTCCCGCTCCCCGTCTTCCTCTCTCACACACCTACTCCGCCCTCCGCCCCAGCCCGCGCGCTAGCTCCTTCTCTCGCCCGGGG
TTCCTGCCGGTAGCTCTCCGGGTCTTGGCGCGGCGGGGGCGCCCCGGGGGTGCCCTCGCCCTCCCGTTGCGGGCGGGCGGGCGGTATGTG
GCGCCTGGTGCCCCCGAAGCTGGGCCGCCTGTCCCGCTCGCTGAAGCTGGCGGCGCTGGGCAGCCTGTTGGTGCTGATGGTGCTGCACTC
GCCGTCGCTGCTCGCCTCTTGGCAGCGCAACGAACTGACCGACCGGCGCTTCCTGCAGCTCAATAAGTGCCCGGCGTGCTTCGGCACGAG
CTGGTGCCGCCGCTTCCTCAACGGGCAGGTGGTATTCGAGGCGTGGGGCCGCTTGCGCCTGCTGGACTTCCTCAACGTGAAGAACGTGTA
CTTCGCGCAGTACGGCGAGCCCCGCGAGGGCGGCCGCCGCCGAGTGGTGCTCAAGCGCCTCGGCTCGCAGCGCGAGCTGGCGCAGCTCGA
CCAGAGCATCTGCAAGCGGGCCACCGGCCGGCCCCGCTGCGACCTGCTGCAGGCCATGCCCCGGACCGAGTTCGCGCGCCTCAACGGCGA
CGTGCGTCTGCTCACGCCCGAGGCGGTGGAGGGCTGGTCGGACCTGGTGCACTGCCCCTCGCAGCGCCTTCTCGACCGCCTGGTGCGCCG
CTACGCGGAGACCAAGGACTCGGGCAGCTTCCTGCTTCGCAACCTCAAGGACTCGGAGCGCATGCAGCTGCTGCTGACCCTGGCCTTCAA
CCCCGAGCCGCTGGTGCTACAGATGACATTTGATCCAGAAATCTTCTTCAATGTTTTACTGCCACCAATTATATTTCATGCAGGATATAG
TCTAAAGAAGAGACACTTTTTTCAAAACTTAGGATCTATTTTAACGTATGCCTTCTTGGGAACTGCCATCTCCTGCATCGTCATAGGGTT
AATTATGTATGGTTTTGTGAAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTC
ACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGA
GAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGC
AGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTT
GACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGC
TGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAAT
AAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAA
TCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCT
GAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGC
TATTCGGAACACAGAATCTCAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGG
AACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGA
AGCAAATAACTTGGATAAAAACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACC
AATTTTAACCCACTCTGGTCCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTA
TGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTG
CAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGG
AGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAATCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCA
AGACTCACTGAGGAATACAAGCCAAGCTGATGAGGCAGTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAA
AGCCTTGTCACATGGATCCTCTGGTGCCTGAAGAAATGAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCA
GCCATTCTGATTACTGGATTGGCTGGGGTGGGGATGGAGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAG
GGCATTTCTGCTGCGAATGCGGCTCTCCAGGCCCTTCACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGA
AAGCTTCTGAGAGTAAACATTTTGCTCCTAAGCTGAAGGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGAC
TCCCATTTGCTCTCAGTGACCCCAGGGCAGAGCCCAGAGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGA
AGAACCTATTGTTCTTCTTGGCATCCTTCTTATGCTACTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAA
TGCAGCACCACTTTCAAGCTTAGTAGGACCATTCCAAGAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTC
CCGTCCTTGCCTGCATGTGAGTCACTTCTTGGCTGTGCAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTG
TGTTGCTCTCTACCTGGCAGCAGACTGTGCAGGAGCCCCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAG
GGCGAGAGGAACAGAGCCAATGATGTGTGGGTTACACTGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATG
GCCTGCATTCCAGAGACCAACATGATAGCTTTTAATTCAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACC
TCTTGAAATCCAGATGTTCATATTAGACTCGAAAAAATAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGT
AGGGAATGACATCTTCCTTGGACCCAAAGCTTAAAAGTAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGT
GGTGGTATCAGGCACACTGCTATGTGCATCAATTATTTTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAG
TATAACTTTGTCATTTCAGGTAAATATGACAAGTGGTGGAGCATGAAGTTTTCTAATTTGACTTAATCCTAATAAATTTTTGTTACAAAG


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FusionGenePPI for C3orf58_SLC9A9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
C3orf58RNF123, GOLPH3, GOLPH3L, HTR3C, CHRNA9, GFAP, TPTESLC9A9ZDHHC17, TP53


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for C3orf58_SLC9A9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for C3orf58_SLC9A9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneC3orf58C0004352Autistic Disorder1CTD_human
HgeneC3orf58C1510586Autism Spectrum Disorders1CTD_human
TgeneSLC9A9C0004352Autistic Disorder1CTD_human