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Fusion gene ID: 4867 |
FusionGeneSummary for C1orf198_RGPD5 |
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Fusion gene information | Fusion gene name: C1orf198_RGPD5 | Fusion gene ID: 4867 | Hgene | Tgene | Gene symbol | C1orf198 | RGPD5 | Gene ID | 84886 | 84220 |
Gene name | chromosome 1 open reading frame 198 | RANBP2-like and GRIP domain containing 5 | |
Synonyms | - | BS-63|BS63|HEL161|RGP5 | |
Cytomap | 1q42.2 | 2q13 | |
Type of gene | protein-coding | protein-coding | |
Description | uncharacterized protein C1orf198 | RANBP2-like and GRIP domain-containing protein 5/6RANBP2-like and GRIP domain-containing protein 5epididymis luminal protein 161ran-binding protein 2-like 1ran-binding protein 2-like 1/2ranBP2-like 1ranBP2-like 1/2ranBP2L1sperm membrane protein BS | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q9H425 | Q99666 | |
Ensembl transtripts involved in fusion gene | ENST00000366663, ENST00000470540, ENST00000427697, ENST00000523410, | ENST00000393283, ENST00000272454, ENST00000016946, ENST00000495582, | |
Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 1 X 1 X 1=1 |
# samples | 3 | 1 | |
** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: C1orf198 [Title/Abstract] AND RGPD5 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BP372051 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000366663 | ENST00000393283 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000366663 | ENST00000272454 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000366663 | ENST00000016946 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000366663 | ENST00000495582 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000470540 | ENST00000393283 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000470540 | ENST00000272454 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000470540 | ENST00000016946 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000470540 | ENST00000495582 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000427697 | ENST00000393283 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000427697 | ENST00000272454 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000427697 | ENST00000016946 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000427697 | ENST00000495582 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000523410 | ENST00000393283 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000523410 | ENST00000272454 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000523410 | ENST00000016946 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
intron-intron | ENST00000523410 | ENST00000495582 | C1orf198 | chr1 | 230972873 | - | RGPD5 | chr2 | 113128412 | - |
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FusionProtFeatures for C1orf198_RGPD5 |
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Hgene | Tgene |
C1orf198 | RGPD5 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for C1orf198_RGPD5 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for C1orf198_RGPD5 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for C1orf198_RGPD5 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for C1orf198_RGPD5 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |