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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 4673

FusionGeneSummary for C12orf49_MDM2

check button Fusion gene summary
Fusion gene informationFusion gene name: C12orf49_MDM2
Fusion gene ID: 4673
HgeneTgene
Gene symbol

C12orf49

MDM2

Gene ID

79794

4193

Gene namechromosome 12 open reading frame 49MDM2 proto-oncogene
Synonyms-ACTFS|HDMX|hdm2
Cytomap

12q24.22

12q15

Type of geneprotein-codingprotein-coding
DescriptionUPF0454 protein C12orf49E3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, hum
Modification date2018051920180527
UniProtAcc

Q9H741

Q00987

Ensembl transtripts involved in fusion geneENST00000261318, ENST00000548356, 
ENST00000536380, 
ENST00000462284, 
ENST00000356290, ENST00000540827, 
ENST00000258149, ENST00000428863, 
ENST00000393412, ENST00000258148, 
ENST00000544561, ENST00000393410, 
ENST00000393413, ENST00000517852, 
ENST00000545204, ENST00000350057, 
ENST00000360430, ENST00000299252, 
ENST00000348801, ENST00000478070, 
ENST00000544125, 
Fusion gene scores* DoF score4 X 1 X 1=410 X 7 X 6=420
# samples 19
** MAII scorelog2(1/4*10)=1.32192809488736log2(9/420*10)=-2.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C12orf49 [Title/Abstract] AND MDM2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMDM2

GO:0000122

negative regulation of transcription by RNA polymerase II

9271120|17310983

TgeneMDM2

GO:0006511

ubiquitin-dependent protein catabolic process

11278372|15314173|16173922|17310983

TgeneMDM2

GO:0016567

protein ubiquitination

9450543|15878855|19656744|20153724

TgeneMDM2

GO:0031648

protein destabilization

9529249|10360174|15314173

TgeneMDM2

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

11278372

TgeneMDM2

GO:0034504

protein localization to nucleus

10360174

TgeneMDM2

GO:0042176

regulation of protein catabolic process

9153395

TgeneMDM2

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

9529249|10360174

TgeneMDM2

GO:0045184

establishment of protein localization

10360174

TgeneMDM2

GO:0045892

negative regulation of transcription, DNA-templated

9271120

TgeneMDM2

GO:0065003

protein-containing complex assembly

10608892|12915590

TgeneMDM2

GO:0071157

negative regulation of cell cycle arrest

9529249

TgeneMDM2

GO:0071480

cellular response to gamma radiation

16213212

TgeneMDM2

GO:0072717

cellular response to actinomycin D

15314173

TgeneMDM2

GO:1901797

negative regulation of signal transduction by p53 class mediator

16173922


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVGBMTCGA-06-5856-01AC12orf49chr12

117175595

-MDM2chr12

69229609

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000261318ENST00000462284C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000261318ENST00000356290C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000261318ENST00000540827C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000261318ENST00000258149C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000261318ENST00000428863C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000393412C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000258148C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000544561C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000393410C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000393413C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000517852C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000545204C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000350057C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000360430C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000299252C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000348801C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000478070C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000261318ENST00000544125C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-3CDSENST00000548356ENST00000462284C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-3CDSENST00000548356ENST00000356290C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-3CDSENST00000548356ENST00000540827C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-3CDSENST00000548356ENST00000258149C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-3CDSENST00000548356ENST00000428863C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000393412C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000258148C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000544561C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000393410C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000393413C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000517852C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000545204C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000350057C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000360430C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000299252C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000348801C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000478070C12orf49chr12

117175595

-MDM2chr12

69229609

+
intron-intronENST00000548356ENST00000544125C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000536380ENST00000462284C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000536380ENST00000356290C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000536380ENST00000540827C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000536380ENST00000258149C12orf49chr12

117175595

-MDM2chr12

69229609

+
In-frameENST00000536380ENST00000428863C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000393412C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000258148C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000544561C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000393410C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000393413C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000517852C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000545204C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000350057C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000360430C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000299252C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000348801C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000478070C12orf49chr12

117175595

-MDM2chr12

69229609

+
5CDS-intronENST00000536380ENST00000544125C12orf49chr12

117175595

-MDM2chr12

69229609

+

Top

FusionProtFeatures for C12orf49_MDM2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
C12orf49

Q9H741

MDM2

Q00987


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59210_215167437Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59243_301167437Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15210_21552322Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15243_30152322Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03210_21522266Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03243_30122266Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26210_21552322Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26243_30152322Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04210_21527297Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04243_30127297Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03210_215-92219Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03243_301-92219Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02210_2150219Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02243_3010219Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14210_21527271Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14243_30127271Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711243_301228498Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15210_21527297Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15243_30127297Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+0327_10722266DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+0427_10727297DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+0327_107-92219DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+0227_1070219DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+1427_10727271DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+1527_10727297DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59179_185167437MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59190_202167437MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59466_473167437MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15179_18552322MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15190_20252322MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15466_47352322MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03179_18522266MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03190_20222266MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03466_47322266MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26179_18552322MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26190_20252322MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26466_47352322MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04179_18527297MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04190_20227297MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04466_47327297MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03179_185-92219MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03190_202-92219MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03466_473-92219MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02179_1850219MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02190_2020219MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02466_4730219MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14179_18527271MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14190_20227271MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14466_47327271MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711466_473228498MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15179_18527297MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15190_20227297MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15466_47327297MotifNucleolar localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59210_304167437RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59242_331167437RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15210_30452322RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15242_33152322RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03210_30422266RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03242_33122266RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26210_30452322RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26242_33152322RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04210_30427297RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04242_33127297RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03210_304-92219RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03242_331-92219RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02210_3040219RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02242_3310219RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14210_30427271RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14242_33127271RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711242_331228498RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15210_30427297RegionNote=ARF-binding
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15242_33127297RegionNote=Region II
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59299_328167437Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59438_479167437Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15299_32852322Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15438_47952322Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03299_32822266Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03438_47922266Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26299_32852322Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26438_47952322Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04299_32827297Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04438_47927297Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03299_328-92219Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03438_479-92219Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02299_3280219Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02438_4790219Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14299_32827271Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14438_47927271Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711299_328228498Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711438_479228498Zinc fingerRING-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15299_32827297Zinc fingerRanBP2-type
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15438_47927297Zinc fingerRING-type

- In-frame and not-retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneC12orf49chr12:117175595chr12:69229609ENST00000261318-15103_13537206Compositional biasNote=Cys-rich
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711210_215228498Compositional biasNote=Poly-Ser
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+5927_107167437DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+1527_10752322DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+2627_10752322DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+71127_107228498DomainNote=SWIB
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711179_185228498MotifNuclear localization signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711190_202228498MotifNote=Nuclear export signal
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711210_304228498RegionNote=ARF-binding


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FusionGeneSequence for C12orf49_MDM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_307aa
MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEV
TQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKT
IVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_307aa
MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEV
TQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKT
IVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_307aa
MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEV
TQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKT
IVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_307aa
MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEV
TQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKT
IVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_281aa
MVNLAAMVWRRLLRKRWVLALVFGLSLVYFLSSTFKQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDED
TWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQES
EDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQP

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_329aa
MPPGTRACRVPRPGRRAPRPRRDGEPGGHGVAPASAEEVGARPGLRAVARLLPQQHLQAGS_CWCK_TFR_LVGSGFSFRSV_CRI_S_I
SRLRRL_P__RRTRTLR_R__GISSYCVSGRGE_YRFI_RRS_NFLS_LLEMHFMQ_NESPPSITLQQMLGPS_ELAS_R_RER_RGNL_
ESQTGKLNTS_RGL_CS_L_KNTSE_FQRVMC_GK___NYTSFTITRK_RLFSAINF__HTL_QPRRCERV_KGRNPRQRRECGI_FAP_

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_329aa
MPPGTRACRVPRPGRRAPRPRRDGEPGGHGVAPASAEEVGARPGLRAVARLLPQQHLQAGS_CWCK_TFR_LVGSGFSFRSV_CRI_S_I
SRLRRL_P__RRTRTLR_R__GISSYCVSGRGE_YRFI_RRS_NFLS_LLEMHFMQ_NESPPSITLQQMLGPS_ELAS_R_RER_RGNL_
ESQTGKLNTS_RGL_CS_L_KNTSE_FQRVMC_GK___NYTSFTITRK_RLFSAINF__HTL_QPRRCERV_KGRNPRQRRECGI_FAP_

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_329aa
MPPGTRACRVPRPGRRAPRPRRDGEPGGHGVAPASAEEVGARPGLRAVARLLPQQHLQAGS_CWCK_TFR_LVGSGFSFRSV_CRI_S_I
SRLRRL_P__RRTRTLR_R__GISSYCVSGRGE_YRFI_RRS_NFLS_LLEMHFMQ_NESPPSITLQQMLGPS_ELAS_R_RER_RGNL_
ESQTGKLNTS_RGL_CS_L_KNTSE_FQRVMC_GK___NYTSFTITRK_RLFSAINF__HTL_QPRRCERV_KGRNPRQRRECGI_FAP_

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_329aa
MPPGTRACRVPRPGRRAPRPRRDGEPGGHGVAPASAEEVGARPGLRAVARLLPQQHLQAGS_CWCK_TFR_LVGSGFSFRSV_CRI_S_I
SRLRRL_P__RRTRTLR_R__GISSYCVSGRGE_YRFI_RRS_NFLS_LLEMHFMQ_NESPPSITLQQMLGPS_ELAS_R_RER_RGNL_
ESQTGKLNTS_RGL_CS_L_KNTSE_FQRVMC_GK___NYTSFTITRK_RLFSAINF__HTL_QPRRCERV_KGRNPRQRRECGI_FAP_

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_303aa
MPPGTRACRVPRPGRRAPRPRRDGEPGGHGVAPASAEEVGARPGLRAVARLLPQQHLQAGS_CWCK_TFR_LVGSGFSFRSV_CRI_S_I
SRLRRL_P__RRTRTLR_R__GLLEMHFMQ_NESPPSITLQQMLGPS_ELAS_R_RER_RGNL_ESQTGKLNTS_RGL_CS_L_KNTSE_
FQRVMC_GK___NYTSFTITRK_RLFSAINF__HTL_QPRRCERV_KGRNPRQRRECGI_FAP_CH_TLCDLSRST_KWLHCPWQNRTST


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_921nt
ATGGTGAACCTGGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTC
CTCAGCAGCACCTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTT
AGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTA
TATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGC
ACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGG
AAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACT
ATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCT
CAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGT
GTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACA
GGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_921nt
ATGGTGAACCTGGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTC
CTCAGCAGCACCTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTT
AGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTA
TATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGC
ACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGG
AAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACT
ATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCT
CAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGT
GTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACA
GGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_921nt
ATGGTGAACCTGGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTC
CTCAGCAGCACCTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTT
AGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTA
TATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGC
ACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGG
AAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACT
ATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCT
CAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGT
GTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACA
GGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_921nt
ATGGTGAACCTGGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTC
CTCAGCAGCACCTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTT
AGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTA
TATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGC
ACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGG
AAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACT
ATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCT
CAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGT
GTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACA
GGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATT

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_843nt
ATGGTGAACCTGGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTC
CTCAGCAGCACCTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTT
AGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGAC
TATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCT
GAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGAT
TGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGT
GAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGAC
AAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTC
CATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCA

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_988nt
ATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCATGGT
GTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGCAGGA
TCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATC
TCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGC
AGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCC
CCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGA
GAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTC
ATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCAT
TATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAA
TGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_988nt
ATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCATGGT
GTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGCAGGA
TCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATC
TCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGC
AGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCC
CCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGA
GAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTC
ATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCAT
TATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAA
TGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_988nt
ATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCATGGT
GTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGCAGGA
TCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATC
TCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGC
AGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCC
CCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGA
GAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTC
ATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCAT
TATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAA
TGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_988nt
ATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCATGGT
GTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGCAGGA
TCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATC
TCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGC
AGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCC
CCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGA
GAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTC
ATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCAT
TATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAA
TGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_910nt
ATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCATGGT
GTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGCAGGA
TCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATC
TCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGACTATTGGAAATGCACTTCATGCAA
TGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGG
GGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGA
TTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAAC
TTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAG
TTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTAT
GGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTA


* Fusion transcript sequences (Full-length transcript).
>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_6667nt
GGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGGCGCGTAGG
GGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCA
TGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGC
AGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTG
AATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATC
AGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGA
ATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCT
CTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAG
AGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTA
GCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCC
TTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCT
TTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCT
AGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGT
GAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGA
CTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTT
CTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGT
GATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCA
CCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG
CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAA
AATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTG
CAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGG
TCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTT
TTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACT
TCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTT
GTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAA
AATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTC
TTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAG
GGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACA
GGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTT
ATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACA
CACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTG
GCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAA
ATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTT
CAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGC
TCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATT
GTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAAT
AATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAG
TGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCA
AAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAG
ACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAA
ATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGA
TGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGT
TAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATAT
GCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTC
TTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTC
TGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAA
CTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTG
TGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCAC
TTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTA
AAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAA
ATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACA
ATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAG
CAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAA
CTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTG
TCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAAC
CAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAG
CTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATC
TGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAA
ATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAA
ATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTG
GGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTT
GAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTC
TCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCAC
CGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTC
TTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGG
GACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTT
GCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGC
CTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCA
GGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCC
TAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAG
TTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAA
GTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGA
TATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAACCGTAAAGC

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_6664nt
GGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGGCGCGTAGG
GGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCA
TGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGC
AGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTG
AATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATC
AGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGA
ATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCT
CTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAG
AGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTA
GCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCC
TTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCT
TTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCT
AGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGT
GAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGA
CTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTT
CTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGT
GATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCA
CCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG
CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAA
AATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTG
CAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGG
TCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTT
TTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACT
TCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTT
GTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAA
AATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTC
TTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAG
GGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACA
GGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTT
ATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACA
CACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTG
GCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAA
ATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTT
CAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGC
TCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATT
GTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAAT
AATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAG
TGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCA
AAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAG
ACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAA
ATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGA
TGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGT
TAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATAT
GCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTC
TTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTC
TGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAA
CTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTG
TGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCAC
TTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTA
AAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAA
ATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACA
ATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAG
CAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAA
CTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTG
TCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAAC
CAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAG
CTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATC
TGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAA
ATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAA
ATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTG
GGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTT
GAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTC
TCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCAC
CGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTC
TTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGG
GACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTT
GCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGC
CTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCA
GGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCC
TAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAG
TTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAA
GTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGA
TATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAACCGTAAAGC

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_6664nt
GGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGGCGCGTAGG
GGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCA
TGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGC
AGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTG
AATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATC
AGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGA
ATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCT
CTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAG
AGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTA
GCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCC
TTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCT
TTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCT
AGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGT
GAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGA
CTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTT
CTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGT
GATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCA
CCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG
CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAA
AATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTG
CAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGG
TCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTT
TTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACT
TCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTT
GTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAA
AATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTC
TTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAG
GGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACA
GGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTT
ATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACA
CACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTG
GCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAA
ATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTT
CAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGC
TCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATT
GTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAAT
AATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAG
TGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCA
AAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAG
ACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAA
ATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGA
TGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGT
TAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATAT
GCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTC
TTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTC
TGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAA
CTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTG
TGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCAC
TTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTA
AAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAA
ATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACA
ATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAG
CAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAA
CTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTG
TCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAAC
CAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAG
CTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATC
TGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAA
ATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAA
ATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTG
GGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTT
GAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTC
TCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCAC
CGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTC
TTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGG
GACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTT
GCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGC
CTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCA
GGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCC
TAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAG
TTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAA
GTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGA
TATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAACCGTAAAGC

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_6664nt
GGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGGCGCGTAGG
GGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCA
TGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGC
AGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTG
AATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATC
AGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGA
ATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCT
CTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAG
AGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTA
GCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCC
TTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCT
TTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCT
AGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGT
GAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGA
CTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTT
CTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGT
GATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCA
CCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG
CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAA
AATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTG
CAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGG
TCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTT
TTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACT
TCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTT
GTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAA
AATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTC
TTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAG
GGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACA
GGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTT
ATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACA
CACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTG
GCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAA
ATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTT
CAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGC
TCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATT
GTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAAT
AATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAG
TGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCA
AAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAG
ACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAA
ATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGA
TGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGT
TAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATAT
GCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTC
TTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTC
TGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAA
CTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTG
TGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCAC
TTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTA
AAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAA
ATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACA
ATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAG
CAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAA
CTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTG
TCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAAC
CAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAG
CTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATC
TGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAA
ATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAA
ATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTG
GGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTT
GAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTC
TCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCAC
CGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTC
TTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGG
GACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTT
GCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGC
CTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCA
GGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCC
TAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAG
TTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAA
GTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGA
TATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAACCGTAAAGC

>In-frame_C12orf49_ENST00000261318_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_6586nt
GGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGGCGCGTAGG
GGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCTGGCGGCCA
TGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCACCTTCAAGC
AGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTG
AATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGACTATTGGAAATGCACTTCAT
GCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATA
AAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGA
ATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCAT
CAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAAT
CTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATC
TTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAA
CTTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCAC
ATATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTT
ACTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTG
GTTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGA
GTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTAC
AGTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGA
CCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTG
ATATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCC
CAGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTA
CAGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGA
CCTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATT
TTAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGG
CTCACTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCA
GCTGATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACC
TCAGCCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTC
TCCAAAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAA
CAATAGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTA
AGTAGGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGG
AGTAATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGG
CCCTTTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAA
AGTACCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAA
GTTAATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGC
ATCATTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAG
GCCCATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAA
GGTGTTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAA
GCAACTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAA
CTACTGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAG
TTCAGGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTT
AACAGGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACT
TAGAACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAAC
AGATAATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTT
ACGCTATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTT
GCAGTAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGA
TTTTAATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTC
TTTTAATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAAT
ACTAAGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTT
TGCAATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGC
ACACAAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGA
CCTCCAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATG
TTCTTGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATAC
ACCATATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAAT
ATGAATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATA
AAATCAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTC
TCTCTCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATAC
TTCAGCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTG
ATAATATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAA
CCAAGCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGC
TATTTTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACG
TGTTGAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAAT
ATCATATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATC
ACTGGGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTT
CTCCCTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTT
TGGGCTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAA
GCTGGGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCT
AAGCCAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTG
AGACGGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGG
TTCTGCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCA
CTATGTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCG
CCACGCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTG
AAAAGTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAA
AATTGTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATA
CTTTGAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATA

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000462284_chr12_69229609_+_6675nt
GTCACGTGGGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGG
CGCGTAGGGGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCT
GGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCAC
CTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATT
TGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTAC
TGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAA
TGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGG
GGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGA
TTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAAC
TTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAG
TTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTAT
GGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTA
TTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATAT
ATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTA
TAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTT
TTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGC
AGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTC
ATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTC
GTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATAT
AAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGG
CTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGG
CATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTC
AAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAG
ATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCA
CTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTG
ATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAG
CCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCA
AAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAAT
AGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTA
GGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTA
ATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCT
TTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTA
CCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTA
ATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCA
TTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCC
ATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTG
TTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAA
CTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTAC
TGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCA
GGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACA
GGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGA
ACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGAT
AATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGC
TATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAG
TAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTT
AATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTT
AATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTA
AGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCA
ATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACAC
AAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTC
CAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCT
TGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCA
TATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGA
ATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAAT
CAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTC
TCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCA
GCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAA
TATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAA
GCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATT
TTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTT
GAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCA
TATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTG
GGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCC
CTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGG
CTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTG
GGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGC
CAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGAC
GGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCT
GCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTAT
GTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCAC
GCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAA
GTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATT
GTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTT
GAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000356290_chr12_69229609_+_6672nt
GTCACGTGGGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGG
CGCGTAGGGGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCT
GGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCAC
CTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATT
TGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTAC
TGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAA
TGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGG
GGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGA
TTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAAC
TTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAG
TTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTAT
GGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTA
TTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATAT
ATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTA
TAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTT
TTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGC
AGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTC
ATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTC
GTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATAT
AAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGG
CTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGG
CATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTC
AAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAG
ATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCA
CTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTG
ATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAG
CCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCA
AAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAAT
AGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTA
GGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTA
ATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCT
TTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTA
CCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTA
ATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCA
TTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCC
ATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTG
TTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAA
CTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTAC
TGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCA
GGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACA
GGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGA
ACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGAT
AATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGC
TATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAG
TAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTT
AATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTT
AATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTA
AGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCA
ATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACAC
AAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTC
CAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCT
TGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCA
TATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGA
ATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAAT
CAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTC
TCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCA
GCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAA
TATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAA
GCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATT
TTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTT
GAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCA
TATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTG
GGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCC
CTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGG
CTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTG
GGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGC
CAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGAC
GGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCT
GCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTAT
GTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCAC
GCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAA
GTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATT
GTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTT
GAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000540827_chr12_69229609_+_6672nt
GTCACGTGGGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGG
CGCGTAGGGGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCT
GGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCAC
CTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATT
TGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTAC
TGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAA
TGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGG
GGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGA
TTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAAC
TTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAG
TTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTAT
GGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTA
TTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATAT
ATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTA
TAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTT
TTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGC
AGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTC
ATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTC
GTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATAT
AAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGG
CTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGG
CATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTC
AAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAG
ATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCA
CTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTG
ATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAG
CCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCA
AAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAAT
AGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTA
GGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTA
ATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCT
TTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTA
CCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTA
ATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCA
TTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCC
ATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTG
TTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAA
CTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTAC
TGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCA
GGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACA
GGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGA
ACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGAT
AATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGC
TATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAG
TAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTT
AATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTT
AATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTA
AGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCA
ATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACAC
AAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTC
CAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCT
TGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCA
TATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGA
ATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAAT
CAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTC
TCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCA
GCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAA
TATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAA
GCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATT
TTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTT
GAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCA
TATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTG
GGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCC
CTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGG
CTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTG
GGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGC
CAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGAC
GGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCT
GCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTAT
GTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCAC
GCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAA
GTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATT
GTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTT
GAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000258149_chr12_69229609_+_6672nt
GTCACGTGGGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGG
CGCGTAGGGGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCT
GGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCAC
CTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATT
TGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTAC
TGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAA
TGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGG
GGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGA
TTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAAC
TTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAG
TTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTAT
GGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTA
TTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATAT
ATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTA
TAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTT
TTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGC
AGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTC
ATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTC
GTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATAT
AAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGG
CTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGG
CATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTC
AAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAG
ATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCA
CTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTG
ATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAG
CCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCA
AAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAAT
AGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTA
GGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTA
ATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCT
TTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTA
CCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTA
ATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCA
TTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCC
ATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTG
TTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAA
CTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTAC
TGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCA
GGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACA
GGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGA
ACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGAT
AATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGC
TATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAG
TAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTT
AATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTT
AATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTA
AGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCA
ATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACAC
AAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTC
CAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCT
TGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCA
TATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGA
ATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAAT
CAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTC
TCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCA
GCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAA
TATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAA
GCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATT
TTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTT
GAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCA
TATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTG
GGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCC
CTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGG
CTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTG
GGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGC
CAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGAC
GGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCT
GCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTAT
GTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCAC
GCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAA
GTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATT
GTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTT
GAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAAAAC

>In-frame_C12orf49_ENST00000536380_chr12_117175595_-_MDM2_ENST00000428863_chr12_69229609_+_6594nt
GTCACGTGGGGCTGCGCCCAAGGCTGCCGGGAGCAGACTGGGCTGCGGGCGGCGGGGCCGGCGCCTGCCTGGAGGGATGGGGCTGCCGGG
CGCGTAGGGGCCATGCCGCCCGGGACCCGGGCCTGCCGCGTTCCGCGCCCCGGCCGCCGCGCCCCACGTCCGCGCCGGGATGGTGAACCT
GGCGGCCATGGTGTGGCGCCGGCTTCTGCGGAAGAGGTGGGTGCTCGCCCTGGTCTTCGGGCTGTCGCTCGTCTACTTCCTCAGCAGCAC
CTTCAAGCAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATT
TGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGACTATTGGAAATG
CACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGG
GAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAAC
TATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTC
TCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAG
TGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAAC
AGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGAT
TGTGCTAACTTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAAT
TTATTCACATATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGT
GAATACTTACTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGA
AGTACTTGGTTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCC
AGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCT
TGGCCTACAGTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGA
TCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAG
TACCTTTGATATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCT
CTGTCGCCCAGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGC
TGGGATTACAGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGA
ACTCCTGACCTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTA
TTTAAATTTTAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGT
GATCTCGGCTCACTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCA
CCATACCAGCTGATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATC
TACTCACCTCAGCCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAG
TTTCTCTCTCCAAAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCT
TGATTTAACAATAGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCA
AAGTGCTAAGTAGGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAA
GGGATGGGAGTAATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATT
ACATCAGGCCCTTTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGA
CACTTTAAAGTACCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAAT
TCAGAAAAGTTAATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGA
AATTATGCATCATTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGT
CAGTGGAGGCCCATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGC
TGTTGCAAGGTGTTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCAT
TCTGTAAAGCAACTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATG
GAATAAAACTACTGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACT
ACGGAAAGTTCAGGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATA
TAACAGTTAACAGGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTT
TGGAGACTTAGAACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTC
TACAAAACAGATAATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATA
AAATAGTTACGCTATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAA
TTTTCTTTGCAGTAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTT
TATTTTGATTTTAATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTT
TTGATCTCTTTTAATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTT
TGGCAAATACTAAGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCA
GTGCCTTTTGCAATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTG
TTAATTGCACACAAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGC
TTTGAGGACCTCCAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGT
ATTGAATGTTCTTGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACA
GTACATACACCATATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTAT
ATTTAAATATGAATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGA
AGACAATAAAATCAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAA
ACTCTCTCTCTCTCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTT
GATAATACTTCAGCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATT
TGGAGTTGATAATATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGA
AGCTAGAACCAAGCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCA
GTGACAGCTATTTTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTAT
AGTACACGTGTTGAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATT
ATTTGAATATCATATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATA
CAAATATCACTGGGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAAT
GCTGTGTTCTCCCTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGA
GGGGAGTTTGGGCTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGT
TCCACCAAGCTGGGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGT
GGGCCCCTAAGCCAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTT
ATTTTTTGAGACGGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGT
TCAAGTGGTTCTGCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATG
AAGTTTCACTATGTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGC
GTGAGCCGCCACGCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATG
GCATTGTGAAAAGTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCA
GCTTAAAAAATTGTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTAC
AAATAATACTTTGAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAG


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FusionGenePPI for C12orf49_MDM2


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check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
C12orf49ELAVL1, KRT31, TRIM54, TP53, PLSCR1, ASPHD2, HTRA1, KNTC1, ZWILCH, KIAA1715, SCCPDH, ACP2, ARV1, CANX, SLC30A7, ATP2B2, METTL9, PEX19MDM2TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59170_306167437MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15170_30652322MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03170_30622266MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26170_30652322MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04170_30627297MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03170_306-92219MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02170_3060219MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14170_30627271MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15170_30627297MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15150_23052322PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03150_23022266PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26150_23052322PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04150_23027297PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03150_230-92219PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02150_2300219PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14150_23027271PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15150_23027297PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59223_232167437USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000299252+15223_23252322USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000348801+03223_23222266USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000356290+26223_23252322USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000360430+04223_23227297USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000393412+03223_232-92219USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000393413+02223_2320219USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000428863+14223_23227271USP7
TgeneMDM2chr12:117175595chr12:69229609ENST00000540827+15223_23227297USP7


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711170_306228498MTBP
TgeneMDM2chr12:117175595chr12:69229609ENST00000258149+59150_230167437PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711150_230228498PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr12:117175595chr12:69229609ENST00000462284+711223_232228498USP7


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for C12orf49_MDM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneMDM2Q00987DB01593ZincE3 ubiquitin-protein ligase Mdm2small moleculeapproved|investigational

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RelatedDiseases for C12orf49_MDM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMDM2C0007131Non-Small Cell Lung Carcinoma2CTD_human
TgeneMDM2C0007621Neoplastic Cell Transformation1CTD_human
TgeneMDM2C0019693HIV Infections1CTD_human
TgeneMDM2C0021364Male infertility1CTD_human
TgeneMDM2C0025202melanoma1CTD_human
TgeneMDM2C0032927Precancerous Conditions1CTD_human
TgeneMDM2C0033578Prostatic Neoplasms1CTD_human
TgeneMDM2C1458155Mammary Neoplasms1CTD_human