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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 4428

FusionGeneSummary for BRE_GPN1

check button Fusion gene summary
Fusion gene informationFusion gene name: BRE_GPN1
Fusion gene ID: 4428
HgeneTgene
Gene symbol

BRE

GPN1

Gene ID

11321

Gene nameGPN-loop GTPase 1
SynonymsATPBD1A|MBDIN|NTPBP|RPAP4|XAB1
Cytomap

2p23.3

Type of geneprotein-coding
DescriptionGPN-loop GTPase 1ATP(GTP)-binding proteinMBD2-interacting proteinRNA polymerase II associated protein 4RNAPII-associated protein 4XPA binding protein 1, GTPase
Modification date20180523
UniProtAcc

Q9HCN4

Ensembl transtripts involved in fusion geneENST00000344773, ENST00000379624, 
ENST00000342045, ENST00000379632, 
ENST00000361704, ENST00000603461, 
ENST00000515877, ENST00000503738, 
ENST00000458167, ENST00000424214, 
ENST00000407583, ENST00000264718, 
ENST00000610189, ENST00000461249, 
Fusion gene scores* DoF score7 X 7 X 6=2943 X 3 X 4=36
# samples 94
** MAII scorelog2(9/294*10)=-1.70781924850669
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BRE [Title/Abstract] AND GPN1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationDDR (DNA damage repair) gene involved fusion gene, retained protein feature but frameshift.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVUCECTCGA-B5-A0JN-01ABREchr2

28152775

+GPN1chr2

27872982

+
TCGARVUCSTCGA-N9-A4Q1-01ABREchr2

28117551

+GPN1chr2

27870703

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000344773ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000344773ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000344773ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000344773ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000344773ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000344773ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000344773ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
5CDS-intronENST00000344773ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379624ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379624ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000379624ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000379624ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379624ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379624ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379624ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
5CDS-intronENST00000379624ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000342045ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000342045ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000342045ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000342045ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000342045ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000342045ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000342045ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
5CDS-intronENST00000342045ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379632ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379632ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000379632ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000379632ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379632ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379632ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000379632ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
5CDS-intronENST00000379632ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000361704ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000361704ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000361704ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
In-frameENST00000361704ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000361704ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000361704ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000361704ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
5CDS-intronENST00000361704ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000515877BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000503738BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000458167BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000424214BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000407583BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000264718BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-3CDSENST00000603461ENST00000610189BREchr2

28152775

+GPN1chr2

27872982

+
3UTR-intronENST00000603461ENST00000461249BREchr2

28152775

+GPN1chr2

27872982

+
Frame-shiftENST00000344773ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000344773ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
5CDS-3UTRENST00000344773ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379624ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
5CDS-3UTRENST00000379624ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000342045ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
5CDS-3UTRENST00000342045ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000379632ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
5CDS-3UTRENST00000379632ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
Frame-shiftENST00000361704ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
5CDS-3UTRENST00000361704ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000515877BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000503738BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000458167BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000424214BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000407583BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000264718BREchr2

28117551

+GPN1chr2

27870703

+
intron-3CDSENST00000603461ENST00000610189BREchr2

28117551

+GPN1chr2

27870703

+
intron-3UTRENST00000603461ENST00000461249BREchr2

28117551

+GPN1chr2

27870703

+

Top

FusionProtFeatures for BRE_GPN1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BRE

GPN1

Q9HCN4

Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. Small GTPase required for proper nuclear import of RNApolymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May actat an RNAP assembly step prior to nuclear import(PubMed:21768307). Forms an interface between the RNA polymeraseII enzyme and chaperone/scaffolding proteins, suggesting that itis required to connect RNA polymerase II to regulators of proteincomplex formation (PubMed:17643375). May be involved in nuclearlocalization of XPA (PubMed:11058119).{ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544,ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for BRE_GPN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_97aa
MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGETLKFTEESHEEPAFQNFMQESMAQY


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_291nt
ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGAT
GCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATA
CCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_1073nt
GAGTGCGCACGCATCCTGCCCGCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCG
GTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTC
TCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGC
ACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCAT
GAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCACT
TGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCCTC
AGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCTGA
TTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCATTT
GAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGATGT
ATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGCTT
ATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCAGG

>In-frame_BRE_ENST00000344773_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_1073nt
GAGTGCGCACGCATCCTGCCCGCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCG
GTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTC
TCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGC
ACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCAT
GAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCACT
TGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCCTC
AGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCTGA
TTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCATTT
GAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGATGT
ATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGCTT
ATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCAGG

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_1052nt
GCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTC
CAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTG
GTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCC
AACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAAT
TTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCACTTGTTTCTAGAAGTCCAGAATT
TTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCCTCAGAGTAGCAAAGTTTCTCTTA
TTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCTGATTATTCCTTGGCCTTTCCCTT
GTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCATTTGAACTCAAGTACTTTTGCTGC
TGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGATGTATAGCCTCTACTCCCCCAGCT
TCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGCTTATCCAGAACGGTGGCAGAGTC
TCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCAGGTTTGTTGAAAAAAGTGGGCAA

>In-frame_BRE_ENST00000379624_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_1052nt
GCGGCGCGCGCGCAGGTCGGTGCGTCTGTCGGGGGCGCGCTCGGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTC
CAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTG
GTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCC
AACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAAT
TTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCACTTGTTTCTAGAAGTCCAGAATT
TTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCCTCAGAGTAGCAAAGTTTCTCTTA
TTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCTGATTATTCCTTGGCCTTTCCCTT
GTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCATTTGAACTCAAGTACTTTTGCTGC
TGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGATGTATAGCCTCTACTCCCCCAGCT
TCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGCTTATCCAGAACGGTGGCAGAGTC
TCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCAGGTTTGTTGAAAAAAGTGGGCAA

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_1076nt
GGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAA
ACACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATG
CTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGC
TGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGC
CATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTC
ACTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTC
CTCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGC
TGATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCA
TTTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGA
TGTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAG
CTTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTC

>In-frame_BRE_ENST00000342045_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_1076nt
GGGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAA
ACACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATG
CTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGC
TGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGC
CATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTC
ACTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTC
CTCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGC
TGATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCA
TTTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGA
TGTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAG
CTTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTC

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_1075nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAAA
CACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGC
TCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCT
GCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCC
ATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCA
CTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCC
TCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCT
GATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCAT
TTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGAT
GTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGC
TTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCA

>In-frame_BRE_ENST00000379632_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_1075nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGAAGCAAGAGATAAAGTAATAATGGGTACTGTGGGGAAAAA
CACAGAAGAACAATTCGGTAATATAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGC
TCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCT
GCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTTTACAGAGGAAAGCC
ATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATAAATAGGAGACTTTAGCACACTTCA
CTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGGGGCTCCCATAAGGGATAATTTTCC
TCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGACCCTTGGACCTGGCAGGTTAATGCT
GATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAAGCCTACAACTTCAAGTTTTATCAT
TTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCTCAGATCTCTATTATTAGGCTAGAT
GTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCAGCCAAGGAAAAGGGAAACATGAGC
TTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACACTGTATAGCTCATTATAGGACGTCA

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000458167_chr2_27872982_+_1009nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGG
CCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGA
GGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGA
CATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATA
AATAGGAGACTTTAGCACACTTCACTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGG
GGCTCCCATAAGGGATAATTTTCCTCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGAC
CCTTGGACCTGGCAGGTTAATGCTGATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAA
GCCTACAACTTCAAGTTTTATCATTTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCT
CAGATCTCTATTATTAGGCTAGATGTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCA
GCCAAGGAAAAGGGAAACATGAGCTTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACAC
TGTATAGCTCATTATAGGACGTCAGGTTTGTTGAAAAAAGTGGGCAAGACATGATTAATGAATCAGAATCCTGTTTCATTGGTGACTTGG

>In-frame_BRE_ENST00000361704_chr2_28152775_+_GPN1_ENST00000424214_chr2_27872982_+_1009nt
GGTACCTGTACCCCACGTAGTCGCCGGTTACCGATCGGACTAAGTTCCAGTGGTGATTTACAAGTCAAGTTAAAATGTCCCCAGAAGTGG
CCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGGAATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGA
GGATAACTGACTTAAAATCTGGCTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGA
CATTAAAGTTTACAGAGGAAAGCCATGAAGAGCCAGCATTCCAGAATTTTATGCAAGAATCGATGGCACAATACTGGAAGAGAAACAATA
AATAGGAGACTTTAGCACACTTCACTTGTTTCTAGAAGTCCAGAATTTTGGACCTCCACGTGAAAGAACTGTTCTTACCTCTGAACTGGG
GGCTCCCATAAGGGATAATTTTCCTCAGAGTAGCAAAGTTTCTCTTATTAGAGAAATCTTGTGACTCAGATGAAGTCAGGGATAGAAGAC
CCTTGGACCTGGCAGGTTAATGCTGATTATTCCTTGGCCTTTCCCTTGTATTTATGCAAGGAAGGATATACTGAGCTGATACTCTTCCAA
GCCTACAACTTCAAGTTTTATCATTTGAACTCAAGTACTTTTGCTGCTGAGGAATGGAATCAAAAGAACGTAGTCTCCTGGTGACCACCT
CAGATCTCTATTATTAGGCTAGATGTATAGCCTCTACTCCCCCAGCTTCTTGCTCTTGACCCTGCACTGTAAGTTGCCCTTCTATTAGCA
GCCAAGGAAAAGGGAAACATGAGCTTATCCAGAACGGTGGCAGAGTCTCCTTGGCAATCAACCAACGTTGCTATGAAATATGCCTCACAC
TGTATAGCTCATTATAGGACGTCAGGTTTGTTGAAAAAAGTGGGCAAGACATGATTAATGAATCAGAATCCTGTTTCATTGGTGACTTGG


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FusionGenePPI for BRE_GPN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
BREBABAM1, BRCC3, FAM175B, BARD1, BRCA1, BRCA2, RAD51, TP53, UBE2D1, UIMC1, PHB, RPN2, SHMT2, SSR3, USP7, LRPPRC, SLC25A13, ATG2A, TTC28, FKBP8, DHRS7B, TMX3, UGGT2, MMS19, FAM175A, TNFRSF1A, FAS, COPS5, NCOA3, UBC, SUMO2, GFI1B, GRB2, MDC1, PAXIP1, AKAP2, HNRNPA2B1, OPTN, TFG, DEF6, CHI3L1, HIST1H2BG, EGFR, WWP2, FAM189B, TENC1GPN1MBD2, ZBED1, XPA, WDR48, RPAP2, RPAP3, POLR2J, RPAP1, CCT5, HNRNPH1, PIH1D1, POLR2B, POLR3A, CCT4, HNRNPU, TCP1, POLR2A, URI1, POLR3E, POLR3B, KPNA2, RUVBL1, EFTUD2, CCT8, HSPA8, CCT6A, HSP90AB1, HSP90AA2P, GPN3, PUF60, HNRNPH2, TCOF1, MED17, HNRNPD, ARMCX3, HSPA9, DDB1, UBC, CUL3, CUL5, CDK19, BRCA1, CSNK2A1, SOX2, AGFG1, ALAD, C14orf142, C18orf25, CBS, CRTAP, DBNL, P3H1, PPME1, SURF2, HSPBP1, OGT, GPN2, POLR2M, POLR2G, XPO1, POLR2F, XRCC3, POLR1A, WWP2, LMO2, RPRD1B


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for BRE_GPN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for BRE_GPN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneGPN1C0026640Mouth Neoplasms1CTD_human