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Fusion gene ID: 43784 |
FusionGeneSummary for ZNF90_CMSS1 |
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Fusion gene information | Fusion gene name: ZNF90_CMSS1 | Fusion gene ID: 43784 | Hgene | Tgene | Gene symbol | ZNF90 | CMSS1 | Gene ID | 7643 | 84319 |
Gene name | zinc finger protein 90 | cms1 ribosomal small subunit homolog (yeast) | |
Synonyms | HTF9 | C3orf26 | |
Cytomap | 19p12 | 3q12.1 | |
Type of gene | protein-coding | protein-coding | |
Description | zinc finger protein 90zinc finger protein HTF9 | protein CMSS1 | |
Modification date | 20180403 | 20180519 | |
UniProtAcc | Q03938 | Q9BQ75 | |
Ensembl transtripts involved in fusion gene | ENST00000474284, ENST00000418063, | ENST00000421999, ENST00000496116, ENST00000489081, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 6 X 3 X 7=126 |
# samples | 2 | 8 | |
** MAII score | log2(2/1*10)=4.32192809488736 | log2(8/126*10)=-0.655351828612554 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: ZNF90 [Title/Abstract] AND CMSS1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | LD | TGCT | TCGA-2G-AAH3-01A | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
TCGA | LD | TGCT | TCGA-2G-AAKL-01A | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000474284 | ENST00000421999 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
3UTR-intron | ENST00000474284 | ENST00000496116 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
3UTR-intron | ENST00000474284 | ENST00000489081 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
Frame-shift | ENST00000418063 | ENST00000421999 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
5CDS-intron | ENST00000418063 | ENST00000496116 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
5CDS-intron | ENST00000418063 | ENST00000489081 | ZNF90 | chr19 | 20188944 | + | CMSS1 | chr3 | 99865817 | + |
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FusionProtFeatures for ZNF90_CMSS1 |
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Hgene | Tgene |
ZNF90 | CMSS1 |
May be involved in transcriptional regulation. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF90_CMSS1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ZNF90_CMSS1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
ZNF90 | CMSS1 | SART3, CAND1, S1PR1, GYG1, EGFR, PCDH7, PSME3, MRGBP, MDM2, PEX19, SPANXN3, RPL10, NES, CBX8, FOXI2, FOXL2, FOXS1, PTP4A1, HIST1H1E, HIST1H1T, ACSBG2, FOXA1, TRIM25 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF90_CMSS1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF90_CMSS1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |