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Fusion gene ID: 43738 |
FusionGeneSummary for ZNF804A_MICU3 |
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Fusion gene information | Fusion gene name: ZNF804A_MICU3 | Fusion gene ID: 43738 | Hgene | Tgene | Gene symbol | ZNF804A | MICU3 | Gene ID | 91752 | 286097 |
Gene name | zinc finger protein 804A | mitochondrial calcium uptake family member 3 | |
Synonyms | C2orf10 | EFHA2 | |
Cytomap | 2q32.1 | 8p22 | |
Type of gene | protein-coding | protein-coding | |
Description | zinc finger protein 804A | calcium uptake protein 3, mitochondrialEF hand domain family A2EF-hand domain family, member A2EF-hand domain-containing family member A2mitochondrial uptake family, member 3 | |
Modification date | 20180519 | 20180519 | |
UniProtAcc | Q7Z570 | Q86XE3 | |
Ensembl transtripts involved in fusion gene | ENST00000302277, | ENST00000318063, ENST00000519866, | |
Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 1 X 1 X 1=1 |
# samples | 3 | 1 | |
** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: ZNF804A [Title/Abstract] AND MICU3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | DA397336 | ZNF804A | chr2 | 185676287 | + | MICU3 | chr8 | 16953200 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000302277 | ENST00000318063 | ZNF804A | chr2 | 185676287 | + | MICU3 | chr8 | 16953200 | + |
intron-intron | ENST00000302277 | ENST00000519866 | ZNF804A | chr2 | 185676287 | + | MICU3 | chr8 | 16953200 | + |
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FusionProtFeatures for ZNF804A_MICU3 |
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Hgene | Tgene |
ZNF804A | MICU3 |
May play a role in mitochondrial calcium uptake.{ECO:0000250}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF804A_MICU3 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ZNF804A_MICU3 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF804A_MICU3 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF804A_MICU3 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | ZNF804A | C0005586 | Bipolar Disorder | 5 | PSYGENET |
Hgene | ZNF804A | C0525045 | Mood Disorders | 2 | PSYGENET |
Hgene | ZNF804A | C0007134 | Renal Cell Carcinoma | 1 | CTD_human |
Hgene | ZNF804A | C0036341 | Schizophrenia | 1 | CTD_human |
Hgene | ZNF804A | C0236969 | Substance-Related Disorders | 1 | CTD_human |