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Fusion gene ID: 4359 |
FusionGeneSummary for BRAF_CUX1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BRAF_CUX1 | Fusion gene ID: 4359 | Hgene | Tgene | Gene symbol | BRAF | CUX1 | Gene ID | 673 | 1523 |
| Gene name | B-Raf proto-oncogene, serine/threonine kinase | cut like homeobox 1 | |
| Synonyms | B-RAF1|B-raf|BRAF1|NS7|RAFB1 | CASP|CDP|CDP/Cut|CDP1|COY1|CUTL1|CUX|Clox|Cux/CDP|GOLIM6|Nbla10317|p100|p110|p200|p75 | |
| Cytomap | 7q34 | 7q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase B-raf94 kDa B-raf proteinB-Raf proto-oncogene serine/threonine-protein kinase (p94)B-Raf serine/threonine-proteinmurine sarcoma viral (v-raf) oncogene homolog B1proto-oncogene B-Rafv-raf murine sarcoma viral oncogene | protein CASPCCAAT displacement proteincut homologgolgi integral membrane protein 6homeobox protein cux-1putative protein product of Nbla10317 | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P15056 | Q13948 | |
| Ensembl transtripts involved in fusion gene | ENST00000288602, | ENST00000437600, ENST00000292538, ENST00000393824, ENST00000547394, ENST00000360264, ENST00000425244, ENST00000292535, ENST00000549414, ENST00000556210, ENST00000550008, ENST00000546411, ENST00000560541, | |
| Fusion gene scores | * DoF score | 18 X 12 X 10=2160 | 12 X 13 X 5=780 |
| # samples | 22 | 14 | |
| ** MAII score | log2(22/2160*10)=-3.29545588352617 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(14/780*10)=-2.47804729680464 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BRAF [Title/Abstract] AND CUX1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. Transcription factor involved fusion gene, inframe and retained DNA-binding domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | BRAF | GO:0006468 | protein phosphorylation | 17563371 |
| Hgene | BRAF | GO:0010828 | positive regulation of glucose transmembrane transport | 23010278 |
| Hgene | BRAF | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 19667065 |
| Hgene | BRAF | GO:0043066 | negative regulation of apoptotic process | 19667065 |
| Hgene | BRAF | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 22065586 |
| Hgene | BRAF | GO:0071277 | cellular response to calcium ion | 18567582 |
| Hgene | BRAF | GO:0090150 | establishment of protein localization to membrane | 23010278 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PAAD | TCGA-F2-A44H-01A | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000288602 | ENST00000437600 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000292538 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000393824 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000547394 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000360264 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000425244 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000292535 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000549414 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000556210 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000550008 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| In-frame | ENST00000288602 | ENST00000546411 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
| 5CDS-3UTR | ENST00000288602 | ENST00000560541 | BRAF | chr7 | 140500162 | - | CUX1 | chr7 | 101801840 | + |
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FusionProtFeatures for BRAF_CUX1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BRAF | CUX1 |
| May be involved in intra-Golgi retrograde transport.{ECO:0000269|PubMed:15718469}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 122_129 | 326 | 767 | Compositional bias | Note=Poly-Ser |
| Hgene | BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 6_11 | 326 | 767 | Compositional bias | Note=Poly-Gly |
| Hgene | BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 155_227 | 326 | 767 | Domain | RBD |
| Hgene | BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 234_280 | 326 | 767 | Zinc finger | Phorbol-ester/DAG-type |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292538 | + | 7 | 23 | 502_556 | 235 | 679 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000393824 | + | 6 | 22 | 502_556 | 198 | 640 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000437600 | + | 7 | 23 | 502_556 | 235 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000547394 | + | 6 | 22 | 502_556 | 219 | 663 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 1406_1438 | 224 | 1506 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 1406_1438 | 235 | 1517 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 1406_1438 | 189 | 633 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 1406_1438 | 224 | 1404 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 1406_1438 | 224 | 1484 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 1406_1438 | 224 | 1450 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 1406_1438 | 224 | 1348 | Compositional bias | Note=Ala-rich |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 1117_1204 | 224 | 1506 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 1244_1303 | 224 | 1506 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 542_629 | 224 | 1506 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 934_1021 | 224 | 1506 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 1117_1204 | 235 | 1517 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 1244_1303 | 235 | 1517 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 542_629 | 235 | 1517 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 934_1021 | 235 | 1517 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 1117_1204 | 189 | 633 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 1244_1303 | 189 | 633 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 542_629 | 189 | 633 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 934_1021 | 189 | 633 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 1117_1204 | 224 | 1404 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 1244_1303 | 224 | 1404 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 542_629 | 224 | 1404 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 934_1021 | 224 | 1404 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 1117_1204 | 224 | 1484 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 1244_1303 | 224 | 1484 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 542_629 | 224 | 1484 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 934_1021 | 224 | 1484 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 1117_1204 | 224 | 1450 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 1244_1303 | 224 | 1450 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 542_629 | 224 | 1450 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 934_1021 | 224 | 1450 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 1117_1204 | 224 | 1348 | DNA binding | CUT 3 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 1244_1303 | 224 | 1348 | DNA binding | Homeobox |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 542_629 | 224 | 1348 | DNA binding | CUT 1 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 934_1021 | 224 | 1348 | DNA binding | CUT 2 |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292538 | + | 7 | 23 | 641_678 | 235 | 679 | Topological domain | Lumenal |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000393824 | + | 6 | 22 | 641_678 | 198 | 640 | Topological domain | Lumenal |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000437600 | + | 7 | 23 | 641_678 | 235 | 677 | Topological domain | Lumenal |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000547394 | + | 6 | 22 | 641_678 | 219 | 663 | Topological domain | Lumenal |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292538 | + | 7 | 23 | 620_640 | 235 | 679 | Transmembrane | Helical%3B Anchor for type IV membrane protein |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000393824 | + | 6 | 22 | 620_640 | 198 | 640 | Transmembrane | Helical%3B Anchor for type IV membrane protein |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000437600 | + | 7 | 23 | 620_640 | 235 | 677 | Transmembrane | Helical%3B Anchor for type IV membrane protein |
| Tgene | >CUX1 | chr7:140500162 | chr7:101801840 | ENST00000547394 | + | 6 | 22 | 620_640 | 219 | 663 | Transmembrane | Helical%3B Anchor for type IV membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 428_432 | 326 | 767 | Compositional bias | Note=Poly-Ser |
| Hgene | >BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 457_717 | 326 | 767 | Domain | Protein kinase |
| Hgene | >BRAF | chr7:140500162 | chr7:101801840 | ENST00000288602 | - | 7 | 18 | 463_471 | 326 | 767 | Nucleotide binding | ATP |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292535 | + | 7 | 24 | 56_407 | 224 | 1506 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292538 | + | 7 | 23 | 67_450 | 235 | 679 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000360264 | + | 7 | 24 | 56_407 | 235 | 1517 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000393824 | + | 6 | 22 | 67_450 | 198 | 640 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000425244 | + | 6 | 22 | 56_407 | 189 | 633 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000437600 | + | 7 | 23 | 67_450 | 235 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000546411 | + | 7 | 24 | 56_407 | 224 | 1404 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000547394 | + | 6 | 22 | 67_450 | 219 | 663 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000549414 | + | 7 | 23 | 56_407 | 224 | 1484 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000550008 | + | 7 | 22 | 56_407 | 224 | 1450 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000556210 | + | 7 | 22 | 56_407 | 224 | 1348 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000292538 | + | 7 | 23 | 1_619 | 235 | 679 | Topological domain | Cytoplasmic |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000393824 | + | 6 | 22 | 1_619 | 198 | 640 | Topological domain | Cytoplasmic |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000437600 | + | 7 | 23 | 1_619 | 235 | 677 | Topological domain | Cytoplasmic |
| Tgene | CUX1 | chr7:140500162 | chr7:101801840 | ENST00000547394 | + | 6 | 22 | 1_619 | 219 | 663 | Topological domain | Cytoplasmic |
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FusionGeneSequence for BRAF_CUX1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000437600_chr7_101801840_+_768aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQAD YEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDLSI IQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDSLR ADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLHCL >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292538_chr7_101801840_+_770aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDL SIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDS LRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLH >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000393824_chr7_101801840_+_768aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQAD YEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDLSI IQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDSLR ADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLHCL >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000547394_chr7_101801840_+_770aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDL SIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDS LRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLH >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000360264_chr7_101801840_+_1608aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNP GEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPD VNGMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQ NILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRS ILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQG AADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESP YSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSV SDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVK SLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQ GSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPR VVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSC DGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAP >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000425244_chr7_101801840_+_770aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDL SIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDS LRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLH >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292535_chr7_101801840_+_1608aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNP GEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPD VNGMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQ NILALRSIQGRQRENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRS ILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQG AADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESP YSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSV SDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVK SLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQ GSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPR VVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSC DGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAP >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000549414_chr7_101801840_+_1586aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNP GEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPD VNGMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQ NILALRSIQGRQRGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALKQ APLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAW KDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESPYSQSSELSLTGASRSETPQNSP LPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFI RMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPP EPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGRE PFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPS PKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGE AEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAP >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000556210_chr7_101801840_+_1450aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGPYSTNSISSQSPLQQSPDVNGMAPSPSQSE SAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQ RAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGAS ALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAE RSQLQGPSSSEYWKEWPSAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKL AKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSEST PKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVK EVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPP SVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQA GASDSPSARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPA SATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLFGLPEAAGARDSRDNPLRKKKAANLNSIIHRLEKAAS >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000550008_chr7_101801840_+_1552aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNP GEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQSPD VNGMAPSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQ NILALRSIQGRQRAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISL KKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGS GGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVD TIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQD PLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSP ELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRH SSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELF IEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGG PVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLFGLPEAAGARDSRDNPLRKKKAANL >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000546411_chr7_101801840_+_1506aa MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGADEIEMIMTDLERANQRAEVAQREAETLREQLS SANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQ ADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGPYSTNSISSQSPLQQSPDVNGMAPSPSQSE SAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQ RENPGQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRSILQQARREMEAQ QAALDPALKQAPLSQSDITILTPKLLSTSPMPTVSSYPPLAISLKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQV KNEVGRSGAWKDHWWSAVQPERRNAASSEEAKAEETGGGKEKGSGGSGGGSQPRAERSQLQGPSSSEYWKEWPSAESPYSQSSELSLTGA SRSETPQNSPLPSSPIVPMSKPTKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSK LTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPP IEASKDSKPPEPSDPPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKP WHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALK RAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSGRAAPSSEGDSCDGVEATEGPGSA DTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000437600_chr7_101801840_+_2304nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTT GAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCG GCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGAC TATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCC CTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGT GCAGAGCTGCAAGTCCGTATCACTGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATC ATTCAGTCCATCCAGCGGCCCGATGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTA TTCTACGGACCTGCAGCACCAGCCAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGC TTCCGTGCCCGGAACCAGGAGCTTGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGC GCCGACAACATCAAGCTCTTTGAGAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTAC TCGTCCCAGTACGAGGAGCGCCTGGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGAC AAGGCCACCCTCAGCATGGGGCGTCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTG GTCTTCCTGGTGCTCTACAAGCTGGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292538_chr7_101801840_+_2310nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGA CGCTGTGCAGAGCTGCAAGTCCGTATCACTGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTG AGCATCATTCAGTCCATCCAGCGGCCCGATGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACT GCCCTATTCTACGGACCTGCAGCACCAGCCAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGG GAGCGCTTCCGTGCCCGGAACCAGGAGCTTGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGC CTGCGCGCCGACAACATCAAGCTCTTTGAGAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTG CGGTACTCGTCCCAGTACGAGGAGCGCCTGGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCC TGGGACAAGGCCACCCTCAGCATGGGGCGTCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCAC TGCCTGGTCTTCCTGGTGCTCTACAAGCTGGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000393824_chr7_101801840_+_2304nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTT GAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCG GCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGAC TATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCC CTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGT GCAGAGCTGCAAGTCCGTATCACTGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATC ATTCAGTCCATCCAGCGGCCCGATGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTA TTCTACGGACCTGCAGCACCAGCCAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGC TTCCGTGCCCGGAACCAGGAGCTTGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGC GCCGACAACATCAAGCTCTTTGAGAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTAC TCGTCCCAGTACGAGGAGCGCCTGGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGAC AAGGCCACCCTCAGCATGGGGCGTCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTG GTCTTCCTGGTGCTCTACAAGCTGGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000547394_chr7_101801840_+_2310nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGA CGCTGTGCAGAGCTGCAAGTCCGTATCACTGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTG AGCATCATTCAGTCCATCCAGCGGCCCGATGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACT GCCCTATTCTACGGACCTGCAGCACCAGCCAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGG GAGCGCTTCCGTGCCCGGAACCAGGAGCTTGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGC CTGCGCGCCGACAACATCAAGCTCTTTGAGAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTG CGGTACTCGTCCCAGTACGAGGAGCGCCTGGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCC TGGGACAAGGCCACCCTCAGCATGGGGCGTCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCAC TGCCTGGTCTTCCTGGTGCTCTACAAGCTGGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000360264_chr7_101801840_+_4824nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGG TCAGCCAGGAGGAAAGGGAAAGACCAGCCTGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCG GGGGAGCAGGCTTCCAATACTAATGGTACACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCC AGCCTACCCCTGGCTTCTACAGGAAAATTTGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAG GAAGCCGGAAGCACAAGCATGATTTTTTCAACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGAT GTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGG CAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAG ATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAG AACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGAGAATCCAGGCCAGAGCCTGAACAGACTATTTCAGGAAGTACCGAAACGA AGAAATGGGTCTGAAGGTAACATCACCACCCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCC AAGAGGGAGCTCCAAGTGCAGAAAACTGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCC ATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATC ACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCC GCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGA GCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTG CAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGA GGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCA TACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCC ATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTC ACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTC AGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGC GAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAG GGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAG AGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCC GACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACC TACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAA GGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGG CTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGT GACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGG GTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCC ACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATT CAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGC GACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGG CCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGC CCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCG GGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGC CTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000425244_chr7_101801840_+_2310nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGA CGCTGTGCAGAGCTGCAAGTCCGTATCACTGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTG AGCATCATTCAGTCCATCCAGCGGCCCGATGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACT GCCCTATTCTACGGACCTGCAGCACCAGCCAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGG GAGCGCTTCCGTGCCCGGAACCAGGAGCTTGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGC CTGCGCGCCGACAACATCAAGCTCTTTGAGAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTG CGGTACTCGTCCCAGTACGAGGAGCGCCTGGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCC TGGGACAAGGCCACCCTCAGCATGGGGCGTCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCAC TGCCTGGTCTTCCTGGTGCTCTACAAGCTGGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292535_chr7_101801840_+_4824nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGG TCAGCCAGGAGGAAAGGGAAAGACCAGCCTGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCG GGGGAGCAGGCTTCCAATACTAATGGTACACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCC AGCCTACCCCTGGCTTCTACAGGAAAATTTGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAG GAAGCCGGAAGCACAAGCATGATTTTTTCAACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGAT GTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGG CAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAG ATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAG AACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGAGAATCCAGGCCAGAGCCTGAACAGACTATTTCAGGAAGTACCGAAACGA AGAAATGGGTCTGAAGGTAACATCACCACCCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCC AAGAGGGAGCTCCAAGTGCAGAAAACTGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCC ATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATC ACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCC GCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGA GCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTG CAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGA GGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCA TACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCC ATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTC ACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTC AGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGC GAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAG GGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAG AGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCC GACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACC TACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAA GGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGG CTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGT GACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGG GTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCC ACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATT CAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGC GACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGG CCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGC CCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCG GGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGC CTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000549414_chr7_101801840_+_4758nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGG TCAGCCAGGAGGAAAGGGAAAGACCAGCCTGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCG GGGGAGCAGGCTTCCAATACTAATGGTACACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCC AGCCTACCCCTGGCTTCTACAGGAAAATTTGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAG GAAGCCGGAAGCACAAGCATGATTTTTTCAACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGAT GTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGG CAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAG ATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAG AACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGGTAACATCACCACCCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCC ATCAAGTCCATCCTAGAGCAAGCCAAGAGGGAGCTCCAAGTGCAGAAAACTGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGG AACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAG GCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTC GCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGAC GCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGG AAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAA GAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAG GAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCC CTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTAC CAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTG CTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATC CGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACA TCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCG ATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCA GAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTA GCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGG GAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAG CCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATG AAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCC CAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCA CCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGC AGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCG CCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAG GCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGAC CACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCC GCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCC CGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000556210_chr7_101801840_+_4350nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGT CCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAA AGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGA CAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACT GTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAA AGAGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAG ATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTG TCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCT GCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTC CTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCC TCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAG CGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGT CTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCG GTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTG GCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAG CCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCC GTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACT CCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAG CCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTG CCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAG GAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCC CGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAG AAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCC TCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAG GAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGC ACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCG GGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGC CCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCG CCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCC TCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGC TCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCG GGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGCCGCCAGC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000550008_chr7_101801840_+_4656nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGG TCAGCCAGGAGGAAAGGGAAAGACCAGCCTGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCG GGGGAGCAGGCTTCCAATACTAATGGTACACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCC AGCCTACCCCTGGCTTCTACAGGAAAATTTGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAG GAAGCCGGAAGCACAAGCATGATTTTTTCAACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGAT GTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGG CAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAG ATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAG AACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGAC GCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCC CAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTG AAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTG GACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGG TGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGC GGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGC GCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCC CCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGAC ACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCC CAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTC TGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGAC CCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGT GAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGAC CCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCG GAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTA GGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGG ATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCAC AGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTG AAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATC GAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTC ATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAG GGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAG GAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGC CCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCC GCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGC TCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000546411_chr7_101801840_+_4518nt ATGGCGGCGCTGAGCGGTGGCGGTGGTGGCGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGC GCCGGCGCCGCGGCCTCTTCGGCTGCGGACCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACAT ATAGAGGCCCTATTGGACAAATTTGGTGGGGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGAT GCACTCCAACAAAGAGAACAACAGTTATTGGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTT ACATCTTCTTCCTCTTCTAGCCTTTCAGTGCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAG TCACCACAAAAACCTATCGTTAGAGTCTTCCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGT CTAAAGAAAGCACTGATGATGAGAGGTCTAATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGG GACACTGATATTTCCTGGCTTACTGGAGAAGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAA ACGTTTTTCACCTTAGCATTTTGTGACTTTTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAG CGTTGTAGTACAGAAGTTCCACTGATGTGTGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATA CCACAGGAAGAGGCGTCCTTAGCAGAGACTGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAG ATTGAAATGATCATGACGGACCTTGAAAGGGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCA TCGGCCAATCACTCCCTCCAGCTGGCCTCACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTA GAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAG AATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAG GCTGACTATGAAGAGGTGAAGAAAGAGCTGAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCC AAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGT CCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAA AGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGA CAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACT GTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAA AGAGAGAATCCAGGCCAGAGCCTGAACAGACTATTTCAGGAAGTACCGAAACGAAGAAATGGGTCTGAAGGTAACATCACCACCCGGATC CGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCCAAGAGGGAGCTCCAAGTGCAGAAAACTGCAGAGCCG GCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAG CAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCC ATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAAC CCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTG AAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAG GCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTC CAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCC AGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTG ACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGC ATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAG CTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAG CAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCC GCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCC ATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGA CACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACG GACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCC TGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCTGATGGAC ATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACC GAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAA CGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGTCATCAAC TGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGAC TCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCC GACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACC CCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCC ACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCG CCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGAC TCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGCCGCCAGCCGGGAGGAACCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000437600_chr7_101801840_+_3232nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGC ACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCA GCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCTGAACAT TCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCG CTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGTGCAGAGCTGCAAGTCCGTATCACTGAGGC TGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATCATTCAGTCCATCCAGCGGCCCGATGCCGA GGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTATTCTACGGACCTGCAGCACCAGCCAGCGG TGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGCTTCCGTGCCCGGAACCAGGAGCTTGAGGC CGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGCGCCGACAACATCAAGCTCTTTGAGAAGAT CAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTACTCGTCCCAGTACGAGGAGCGCCTGGACCC CTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGACAAGGCCACCCTCAGCATGGGGCGTCTGGT TCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTGGTCTTCCTGGTGCTCTACAAGCTGGCATG GAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTGCACAAGTTCCACGAGAATGACAACGGGGC TGCGGCTGGTGACTTGTGGCAGTGATACCCCGGGGCCTCCCCCGTGACAGTGACGGCTGCGCCTCCACCCCGACTGCTCAGTGCATCTAA TCACTTAGACTCCCCTGAAGAATCCCCCATGGAAACTGCCCTTATCCGCTGTCCAGCAGCTGCCAGAGGCCCCAGGTCACCTCGGGTCCC CTTGAAAGAATGTCTCGGTCACATCAGGCCCGCTAGGTCCAGAGAGCGAGCCCCCAATGCCCGGCCAGGCTAAGCCGCAGAGACCCTCTC AGCCCCCACCTCAGGTTAGGGCTCTGCCCGCAGCCTGACCTCTAGCCCTGGTGGCAGAGGTCCCTCAGCTGCGAGGCTAATTGGGTGACC ACCGATTCCAGCTGCGGTTAATCCAGCTTGGGCCTGTCTGCACTGCGATCCTCTTGGGCTCTCCTAGGATCCCCCCATGCCCCGTAAGAG GTGGAAGACGCTTCCTTCCAGGACAGCAGGCTTTGAGTCCAGCACCCCCAGCCTGCCTTTGCCACCAGCCCCACCCTGCAGAGTATATGA GGCTTGACAGAGTCTGCCCCCTCCCCCACTGCACCCCAAGAGAGAGAGCCCCAGCCAGCGGAACAGTTTCTATTACCCCCTCCCTGCCCC CAGACCCATGTGATTTCTGCTTTCTTCTTTAGCAAGATATTCTGGTTTCTAGATAAGGAAGAGTCTCTAATGAGCCCCCGAGCCCCAGTC TCTTCAGACTCATGGATTGGTCTGAGGGGTCTGAACGTCTCCTAGCCAATCAGAACTGGCTGTGGACCACCCTAGCACGGCCACCTCTCA >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292538_chr7_101801840_+_3238nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGTGCAGAGCTGCAAGTCCGTATCAC TGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATCATTCAGTCCATCCAGCGGCCCGA TGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTATTCTACGGACCTGCAGCACCAGC CAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGCTTCCGTGCCCGGAACCAGGAGCT TGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGCGCCGACAACATCAAGCTCTTTGA GAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTACTCGTCCCAGTACGAGGAGCGCCT GGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGACAAGGCCACCCTCAGCATGGGGCG TCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTGGTCTTCCTGGTGCTCTACAAGCT GGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTGCACAAGTTCCACGAGAATGACAA CGGGGCTGCGGCTGGTGACTTGTGGCAGTGATACCCCGGGGCCTCCCCCGTGACAGTGACGGCTGCGCCTCCACCCCGACTGCTCAGTGC ATCTAATCACTTAGACTCCCCTGAAGAATCCCCCATGGAAACTGCCCTTATCCGCTGTCCAGCAGCTGCCAGAGGCCCCAGGTCACCTCG GGTCCCCTTGAAAGAATGTCTCGGTCACATCAGGCCCGCTAGGTCCAGAGAGCGAGCCCCCAATGCCCGGCCAGGCTAAGCCGCAGAGAC CCTCTCAGCCCCCACCTCAGGTTAGGGCTCTGCCCGCAGCCTGACCTCTAGCCCTGGTGGCAGAGGTCCCTCAGCTGCGAGGCTAATTGG GTGACCACCGATTCCAGCTGCGGTTAATCCAGCTTGGGCCTGTCTGCACTGCGATCCTCTTGGGCTCTCCTAGGATCCCCCCATGCCCCG TAAGAGGTGGAAGACGCTTCCTTCCAGGACAGCAGGCTTTGAGTCCAGCACCCCCAGCCTGCCTTTGCCACCAGCCCCACCCTGCAGAGT ATATGAGGCTTGACAGAGTCTGCCCCCTCCCCCACTGCACCCCAAGAGAGAGAGCCCCAGCCAGCGGAACAGTTTCTATTACCCCCTCCC TGCCCCCAGACCCATGTGATTTCTGCTTTCTTCTTTAGCAAGATATTCTGGTTTCTAGATAAGGAAGAGTCTCTAATGAGCCCCCGAGCC CCAGTCTCTTCAGACTCATGGATTGGTCTGAGGGGTCTGAACGTCTCCTAGCCAATCAGAACTGGCTGTGGACCACCCTAGCACGGCCAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000393824_chr7_101801840_+_2753nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGAGATCGC ACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGAGCAGCA GCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCTGAACAT TCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAAGAACCG CTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGTGCAGAGCTGCAAGTCCGTATCACTGAGGC TGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATCATTCAGTCCATCCAGCGGCCCGATGCCGA GGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTATTCTACGGACCTGCAGCACCAGCCAGCGG TGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGCTTCCGTGCCCGGAACCAGGAGCTTGAGGC CGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGCGCCGACAACATCAAGCTCTTTGAGAAGAT CAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTACTCGTCCCAGTACGAGGAGCGCCTGGACCC CTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGACAAGGCCACCCTCAGCATGGGGCGTCTGGT TCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTGGTCTTCCTGGTGCTCTACAAGCTGGCATG GAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTGCACAAGTTCCACGAGAATGACAACGGGGC TGCGGCTGGTGACTTGTGGCAGTGATACCCCGGGGCCTCCCCCGTGACAGTGACGGCTGCGCCTCCACCCCGACTGCTCAGTGCATCTAA TCACTTAGACTCCCCTGAAGAATCCCCCATGGAAACTGCCCTTATCCGCTGTCCAGCAGCTGCCAGAGGCCCCAGGTCACCTCGGGTCCC CTTGAAAGAATGTCTCGGTCACATCAGGCCCGCTAGGTCCAGAGAGCGAGCCCCCAATGCCCGGCCAGGCTAAGCCGCAGAGACCCTCTC AGCCCCCACCTCAGGTTAGGGCTCTGCCCGCAGCCTGACCTCTAGCCCTGGTGGCAGAGGTCCCTCAGCTGCGAGGCTAATTGGGTGACC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000547394_chr7_101801840_+_3238nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGTGCAGAGCTGCAAGTCCGTATCAC TGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATCATTCAGTCCATCCAGCGGCCCGA TGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTATTCTACGGACCTGCAGCACCAGC CAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGCTTCCGTGCCCGGAACCAGGAGCT TGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGCGCCGACAACATCAAGCTCTTTGA GAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTACTCGTCCCAGTACGAGGAGCGCCT GGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGACAAGGCCACCCTCAGCATGGGGCG TCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTGGTCTTCCTGGTGCTCTACAAGCT GGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTGCACAAGTTCCACGAGAATGACAA CGGGGCTGCGGCTGGTGACTTGTGGCAGTGATACCCCGGGGCCTCCCCCGTGACAGTGACGGCTGCGCCTCCACCCCGACTGCTCAGTGC ATCTAATCACTTAGACTCCCCTGAAGAATCCCCCATGGAAACTGCCCTTATCCGCTGTCCAGCAGCTGCCAGAGGCCCCAGGTCACCTCG GGTCCCCTTGAAAGAATGTCTCGGTCACATCAGGCCCGCTAGGTCCAGAGAGCGAGCCCCCAATGCCCGGCCAGGCTAAGCCGCAGAGAC CCTCTCAGCCCCCACCTCAGGTTAGGGCTCTGCCCGCAGCCTGACCTCTAGCCCTGGTGGCAGAGGTCCCTCAGCTGCGAGGCTAATTGG GTGACCACCGATTCCAGCTGCGGTTAATCCAGCTTGGGCCTGTCTGCACTGCGATCCTCTTGGGCTCTCCTAGGATCCCCCCATGCCCCG TAAGAGGTGGAAGACGCTTCCTTCCAGGACAGCAGGCTTTGAGTCCAGCACCCCCAGCCTGCCTTTGCCACCAGCCCCACCCTGCAGAGT ATATGAGGCTTGACAGAGTCTGCCCCCTCCCCCACTGCACCCCAAGAGAGAGAGCCCCAGCCAGCGGAACAGTTTCTATTACCCCCTCCC TGCCCCCAGACCCATGTGATTTCTGCTTTCTTCTTTAGCAAGATATTCTGGTTTCTAGATAAGGAAGAGTCTCTAATGAGCCCCCGAGCC CCAGTCTCTTCAGACTCATGGATTGGTCTGAGGGGTCTGAACGTCTCCTAGCCAATCAGAACTGGCTGTGGACCACCCTAGCACGGCCAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000360264_chr7_101801840_+_14076nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGGTCAGCCAGGAGGAAAGGGAAAGACCAGCC TGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCGGGGGAGCAGGCTTCCAATACTAATGGTAC ACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCCAGCCTACCCCTGGCTTCTACAGGAAAATT TGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAGGAAGCCGGAAGCACAAGCATGATTTTTTC AACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCA GTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAA TATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAA ACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGG CAGACAAAGAGAGAATCCAGGCCAGAGCCTGAACAGACTATTTCAGGAAGTACCGAAACGAAGAAATGGGTCTGAAGGTAACATCACCAC CCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCCAAGAGGGAGCTCCAAGTGCAGAAAACTGC AGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGA GGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCAC CTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCT GCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAG ACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTC CGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAG TCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGAC CGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCC CCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAA GAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATG GAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCA GGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAA GACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTG TCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCT CTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGT GCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCC CAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCT GATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGT CGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGC GCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGT CATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGC CAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGG CAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTC GGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGC GACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGC GCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGC CCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGCCGCCAGCCGGGA GGAACCTATCGAATGGGAGTTCTGAGGGGCCGCGGCCCTGGGGCGGGCAGCCAGGCTGGGCCGCAAGGGCCTGGACGGGGTCGGACGGGG CAGGCGCTGCGGACACCGTGGCCTGGGCTTGGCCCGCGGCCTGCACCGACCCCGGGCCGGACCTGAGCCCGCAGCCCAGACCCCCTCCAC GGTCCGCGGCCTGCACCGACCCGAGGCCCAGATCCAAGGCCGCGGCCCAGACCCACTCTGCGGCCCGGGCCGACCCTGCGGCCTCCACCA ACCCCGCGGCCCAGACCCAGCCCGCGGCCTGGACCCCTGGACCGCTTTGCGCACTTACCGCCCTGCGGGCCACAGGGCAAAATCGCCATA GGCCAAGGTGCATATAGAAAACAAAGGAGCATTAAGCCCAATCTATGTCGTGTTTTCAAGGAAGAAAACGGAAATGTGTGGTCGAGCTTT TTTGTACCCTGAAGTGTTTTTTTTATTGCCCTAAGTGATTTCCACAGGTTCTGGAATAACTCTTACAGCTTTGCCTTGTGTCCTCCTGTT CCGTGTGGGCTTTAAAAGAAAAAAAATCAAACCCACATATTAAAAGGGGGCTTTTTATCTGCCATCTAATGGCTTCAGAGCGATAATACA CTATTATCTTCTTAAACCAGGAAAAAATAAAAGGGGGGGTGGGATTTTTCAGAAAAATTAAAAAAGAAAGTTTTTGTAGCTGTTCAGTTG CCACTAAGAGATTGCACAGTCAAAACGACTCTAAACACACTAGTTTGGATTCCTAAATATTTTCAAGAAAAGAATCTTCTCGTTTGAAAC TTTGAATTAAAATAAAACACATTTACTCCACATATTTTTTAACAAAAAGAAAACGTCACATCAGGAAACTCTGATTTTGTGGTAGCTGAC ATAGTGTTTTCTTGTACGTGAATAGAATCCTGACATGTAGTGCACATTGATGTATAGCTTTAACTGACCCTGGGTTTTGCAGACCAGGGT TTGTTTAATACACTCCATTCTAGGCCAAATCAGGACAAAAAAAAGAAAAAAAAAGAAAAAAAAAAAAGAAAAGATCCGAATCTAGGTATT TTATAATCTGCTTTTTAACCTCTAACCGCAGAGCACGCTGATCAGACCTCATATCTTGGAGGTTTAGGAGACAAGTTAGAACTGTAGCAT GTACCTGTTAATTTTGTTTAATTTATGGTGTCTCAATCTGTCTGTGCGTCTGCACGTGTGCAAGCATTGAAAGAAAGGAGAGAGTAGTCC GGGCGAGCACAGCAGGCAGTTCCAGGGCCAGACGGGCCCATCCCCAAGTAGATAGCAGTCTACGGATCTCTCTCTGGCACAGAAGGCACC TCACCTCACACCACTCTCCTGGATACCTGATGAACTGAGCCCTCCCAGGGGAAGACACTCCCCAGGCCTGGGCAGGGCTTACACGCGCAC TCTCTCTCTTCTTTCCCTTTTTCTTCCCACCGCAAGCACTGATGACCCTGTTGAACTCGTGGGAAACTTCCTTTCTCTGCAGGAGAGAGA ACGTGGCATTCTGGGCTCCCCACTCCCATCCCTGTAGAAATGGCCCAAACTCACACCAAAACGTGGATGCTCTTCAACTTCCAAACCTAC CATTTGCCCTTCTTTCATTTCGCCTCTTAGTTCTTTTTATGCACAGTTTTAGGGCAGTCTAAGTACAAACTGAAAGTCTAACTTGTCTCT GATTCCTCCCTTGTCTATGTGTATATGCGTGAGAATAGAGGCGGGTGAGAGTGTGCGTGCGTGTGCGTGTGTGCAATTTTATACGTCTGT GTATTTTCTTAAGTACCTGTGCACACGTAGAGTGCATTACTGCCACCTTTTTCAATAAGCTGTTTTATCAGTTACGGCTTCTACAAGTTT GCTAATTTAGACTTCTTTATTGCCATATCTTTAAACTAACAATAGATGATTTCGGTATATATATATATTTTTTTTTGCTTATTTATAGGT GCTGTATTTTATTATCTGATTGTTAGGAAGGGATGAAAGGGGCAAATATTCTTTAGAGGGATAGACTGCCGGCAGTATTGGGTATAATTT ACAAGATGTAGTTGTCATACTGTATATTACTGATTGAAAACTTTTTGACCGTATTGTGTATCATTGAAACCTTTGTCTTAGGTCAACATC TTTGGATGACATTTTAATGGTGCATTCATTATTTCTTAAGTTTAATTAATATTACTTTTTTTTTTATTTGGGGGGTGGGAGGGAGTTATA ATTTTAAAGGTATGCTCTGGCTGTTCCACCTCCGTGTGCTTGTTAATTAACTTGTAGGACTTTGACTGTAAGATGTGAAACCACGTTTCT TGCATGATGTTTTAGAGATTATTTCATTTACAGTCTTTTAACCTGCAGCTGCAGCACTTAGTTCACGTTTTCACAAATTTCAAGAGTCAC TACACTAAAGACAATGCCTTTTCATGAATAAGAAGTTTTCAGAAGGCTCTAGGGGGCTGGGAGGCAGGCTGTTCGTTTGTCTTTTGTTGG GGGTATCATTTCTGAACTTGAAATCCAGTTCAGGGAGAAGAGAATTCAAAATTAGAGGAGCTTAAGGGGACACGGGTCAACATCTAGCTC GATTCAGGTGCATTGAGAAGAGTGAGTTCACATCGGTGACCCTTAGGACAGTGAGTGGCAGAGCCCTGACGACTGTGGTGTCCTCTCCAC AAAACCCTCAAGGGACTTTTGTCATCATGTGTGATGAATCTTTAAATATCGTCTAATTTTCATAAGAATGAAAAGAAGTTAACAGGAAAT AGTAGGCTAGGGTTTAGTTTTAAAGGCATGACTGTTATTTACAAAGGTGTTAAATCTGAGGAAATTGACAAATACAGATTTGTCCATTCT AGTGGCCAAACAGTAACAGTCTAAAATGCAGTCATTTTGACCCTCCCAAGCAATTTAGTCATATGTGTTGTTTTCTCTTTTCTGTTTTTA CTTCTTAGATTTTTAACTAGGTTACTGTTGGTTCCCATTCTGTCTTTTTTGCCAGACTTACATCTGGTGCCAGATACAATCAGTTGGTTA AATTTTGCTTGCAGTTCTGTGTATTTTTTTTCCTCTATTATTTATTTTTTTAAAAAAAATAGAGATCCTAACCTTAGATCTTTGATGTGA AGCTAGCACTGTCTGTAATACTTCTAAGAGCTGCCACTAAAATAATACAGCAATCCGTGGCCAGGGGAGCACCCCCTCCTGGTTGGGCCC CTCAGTTGGAGTCTAAGGGTTAATCTCTCATCTTGCTAAGCAGTATTCAAGTGCCTTGAACAGTGTCCCCTCGGCATGGCTCCCCTTCAG CAGGCTGGCATTCCAAGCAGTGGCCCCCGCAGGCAGCCGACCCCCTTCCTCTTCACGCTCTATGAGTTTAAAAAGCTGATTTGTACCTCT CCCCTGGGGGAAACGGTTCCATATAAAACACTAACACTTAATTACAAGCTCCATTATGCCATTTTAAATGGCTTCTTTTTGTTAATTGGA GGCATTGTTCATAACTTAAGGCTTTTGCCATTAACTTAGCTGGCTAAGCAGAGGCTCGGGGTAAAATCAGTGTTTGCATTTAGCCTCTTG ACCCGGAGTTCCGGCCCAAGCTCCCTTGTGATAGCCGAGATGGCAGGTGTGTGAGTTCTGTCCTAGACCTGTGCCCAACTCACTTCCACC CCAGAGGAGTCTTCTGTCCTCCTCCCCAACCCCCGAGCTCCCTGGTAACCTCCTCTTGAACTTCTGTATCAGTGAAGACATCTGTGGTTT CTGCTCACCAGACCTCTCTTTAGAAAGGGTTATCAGAGCCATGGAGCTTAGCTCAATTGGATTCTTCTAGACGATCTTAGGAGGCATCTT GGCATGAGGCAGCTTCTAAGCGTCTCCTGGGACAGGATTGGGGTGACAGCCCAGGGATGCATGCATGGGAGAACTCTCTGAGAAATGCCA GGATCGTGGCTCACAGGGACCCACCATCAAAACCTGCTACTTTGTGCAAGTAATTGAGGCAAAAGATACCAGTCGACAGCCTCCCTGGGG TAGATCCCTTGTACCTCCAAAGTACAAATACCTCCCTGCTCAGTTTCCTTCCTGTCGCCATCTTTGTTTTCTTCCCATTGAAAAACCATC CTGTCTGATGTGGACGTTCAGGTCTGCTGGTTGGCGGTCCGGGCCCAGAGTGCAGCAGAGCTCTGGGTTAAATATTCCTTTCTGGCCACC GCCCAAGCCCAGGTGGCCAGCTCTCATACCCCATCTCCCTCCTTGGCCAGGGCCAGCATCAGGCGTGCAGCTCATGACCAGTTTACACAG GCTGCAAAGAGATCGCTGTGGGCCTCGGCTGACTACTTTAAGATTATGCCACAGCCAGGCCCTAAAAAGAGAGGGGAACAGGAGTCCCCA GGTGAGCTCTCTGACGGGCAGGTGCCTTCCCGACTAAGGTTGGACTGGATGACTTTGTTCCTCCTGCATGCATGTCCTTTGATGCAAGGG TGATCAATGAACTCTGTTGACATTCTATGCAATGTTTTTCATTCCTCTGATTTTAGCAAAGCAAATCTTACTGAAAAATAGCAGAGCCAG GGGAACAGACGCATGTCCTTCTGGGAGTCACACAAAAGCAGAGAGATTTTGAACTGAGGGGCGACAGCCTTTGCCTTAAATGCAGTATGA CAGGCGCTTCTTGGCAGACCAGTAAAAACAAAAGCCCATAGACCTTACTCATCCCAAGGCCGACAAGCCAGCTGTACAGGGCGAGATGTA GCAACACGGGGCATGAGCGGTGGGCGTGCTGGGCTATTTGCTGTGGTACTTTAGGCTGGAGGTTTGGCTCCTGTGCTGCCGGTGGGGGGC CCTGTCCCTCCCCAGATGTCCTCCCTCTTCTTCACACTCCTCATTGTCCCTTCTACCTCACTAACCTGTCTTCTCCATCTGATGTCACCC AGAACCACACCCCACAGAACTGTGAGGCACGTGGGCTGGAGAGAGCAGAAAAGCTGCCAGCGCAGCAGACACGAACATCCCTCTGCCTGG TGGGCCGGCTTTGTGTGTCTCTCCTTTTGTGAGCGCAACACGGACAAACAGCTGTGCTCTGCAAGGCACACGGATGTTTCCCTTCCACCT GTTCCCAAAGCTCCAGCAGCTGTTTCTTTTGCAGGCAGGGCGTGGTCTCGGGGCTCCGAGGGTCTTGTCTTTGGTCCGCCTTCCTTTCTG TCCAGTCCTGCTCAGCTGTTAAGATCCATCATGGCCATTATCCTTGTCCCGGACTGCCCCAAAGTTCCCAGCTGGCTTTGGGGAACACTG TAGCTCTTGGGTGTCTCTTGTCTCTGGCATGGTTTTAGCGTCACTGCGAACACTCCTTTGCAAACATCAAACATCTCAAAGACGGAAAAG GATAGATGGCTTCCTCCAGCCTACACGCCCCGTCCACAGTGGCATCACCCTCTTATCCCAAAAGAATATGCCAGTTCCCATCCAGCACCG AAGAAAATCAGCTCCTGGGGCTGGTGGTTGGAGGTGGGTCTGTCCACTGTGGGGGCCAAAGTGTTCCCCTGCTGGAGACAGTTTGCAAGT AAGAACCTAAGGATGGGGACAGCATCCTGTGCTTGGGCATTGACCAGCCAAAGCTCACATTTAGAAAGCCCTCAGTGCTTCTGTGGTTTC ACCTGGGCATCGACGACATTAGGGAAGCCTTTGTGACCACAAGGGCAGGGCTTGTGCCCTGAGTGGCGAGGTGGTGACCTGAGGCCAGTG TGATGTGGTTGGATCTCAGCGTGTACTGAATGCCAGTCTGGCCGGCACACTCGAACGCTAAGAGAATGGTCCAATTTGATGATCTTATTT CTATTTCGATCAGGTTTTGACTTTTTGTAGATGAAAACTACCAGGGAAAAGGGGAAGCAGGTACCCAATAAAGTTTAGAAAGATCCAGTC TGTGAAACCCTTAGAGATGGGCTGAAAGTTAAGTCCACCAACCCTTGGGCTTAATCAGGACGGAAGAGGAGGGGGTGTGGGGGGCAGAGC GTAAAACAAGCCCCAGCCCTACTCCCGGCCCCCCAGCCCAGTCTTCCCAATCCCAGAGGCCCCGGCGGCCTGTGCTCCTCACCACCCTGG TCAGGGGAATAGAAGGAAATGCAATTTCCGCCTGTCTGCCCGACTTCCAAAAACTGCCTCCTCCTGCCCAGGCCTCTCCCACCACCACCT TCCCTCCAAAGATAACCGTGTCCATGCCATCCGTGGCATCATCTCGAGTTTTCATTTTTGGATGAAGTGACATTTAGCTTTAACAAGACA TTTCCAAAGCGCCTAGTCTCCTCCAAAATGCTAACTTTAAAAGTTGGGCATTGTAGGCGAAAAATCCCAAAAAAAAAAAAAGACAAAAAA AAAAGGCTGGCGAGAGAAAGACATTTGGCTATGCATAAATGTGCACTTCCCCCATGCCCCCGTTCTTAAACTCTTAAGATGCCTTTGAGT TGCTTTTCATGAATCCTTTTAGTTTACCCGATAATGTTAAGAAAGCATTAGTCTACGTTACTGTAATTTCTGTAGTGTTTACGCTTTAAT TTCTACCACAAAATATGCTATATGCTATGTATCAAGCTTTCTGTAATCAGAAAGAAAAGGTGCCTTATATCCCAATGTCACGGCTACATC CCTATGGAAATTAATCAGAAGCACAGTGTGTACGGAAGCATTGGGACTTCTGCTGGTGAAACAAGAGACCATTCAGCAAGACACATTGAA GTGGCACGGAGCTGCTTTTGTTTTATAATTCTTTTTTCCCCCCTTTTCCTTCTTCTTTTTTATTATTTTATTATTTTTTTTGTACTTTGC TTTAAACGGAAAGCACTTAAATAGATGACTATGTGTAAAAGCTCTGTGCAATTGAAATCATTTTTCTTCATTTTAAAAAAATAACGTATT GCACACCAAATGAACTCAAAGTAAGCTTTAGACCAGGACGATTCAGGTTATGAATGAGTTTGTTCACTGTAGTTCCGTTTGTTCATGAAC CGAAGGGAAAACAGGCCTCCCCGACTCCCTCCAGTCTCCCAGCCTGCCTCTTGGTGACCACTGTGCTGGGCGTGCAGGGCCCGCGGGCTC TGGCCGGAGCCGCTGGCCTGACGAGGCAGGATAGGGAGTATCCGTGATTCAGAAGCTGAGACCCTTCCCCAGTGTCTGAGGCCACAGCCA TCCCTTCCAGCACTTAATCTTGTCTTGTTGAAATGGACTGACTGCTACTGACCTGCCGGCGTGCGTGAGGGTGATTATAAAAGGATGTTT CCTTGAGAAAAAAAAAATTATTTCTATCCTCTTCTATTTATTATTAGGTTAATCATTTAAGTACTTATCAGGAGTGTATTGTTATTTTGT GTTTTGTTGTCATAAATGCTTTTTGCTGTCACTCTAGTGGTTACTATCCTCTGCCTTCCTCTCCTCCCCTACTCCCCCAGAGAACCAAGG CGTCTGGGGGATTGACTGGGGGGCAGAGGGGGTTTCCCCAGCAAAATCAAACACCTGTCTCCAGAGTAGCCACTCAAAAACTGGTGGTCT CTATGTGTCTAACTTTTTAAATGAGAGTGTTTATGAACAAAAAAATTTACCAACGTGTGAGGGAGTTGCTGAGTTGAAGAATGCTCGCTT GAGGAGCTTCAGAGGAATCTTAGCAAAGCCAAGTTCAGTTCCCCAAAGCCTCCTAGAGCCTCTGGTAAGACTTCTGGGTTCATGAAGTTT CGGCGAGCCGTGGTCAGAGAGGGCGCGGTGGCCTGGCCAAGACTTTACCTCCAAGCGAGAGAGTGATTTCTTGCAAGGCCCGCATGGGTT GATACGTTTTGGTTGGTTTTTTGTTGTTGTTTTTCTTGCGTACAAAGTTGGTCAAAACCATCTTTCAAAGCAACAGTGTTTTGTAGTACC AGGCTGTGGCTTGAGGGCTCACCTAGGAGATCATAGGCAGAGGGCCCCTTTCCCCTATAGGTGGTTCAACGTGGAGGAAGGTTGGGTGTG GAGATTGCTTGCTGTGGCCCCAAGCTCAGCCAGCAGGACACCCAGTTGTTGCCAATCAGGTGTGAAGGTGAGGCGCCCTGCCTTGATCCC ATGGGCCCAGCAGAAGGAAACTTACCCCAGGCCAAGGCAAGGGCCCTGCTCACCCCAAGGTAGGCTGGGAAGAGCATCTCTTTCCATATC ATCACCTCCCCTTCTCCAAGATTGCCGGGGGCCCTGATTTTGTTCTCTCTTTGAAAGAAACCCTCCACCGAAACAATGGTCCCCATCTCC CCAGAAGCCTTTTTTTTTTTCATTTTTCTCTAATTAGTCTATGCATTTCTCTCTCTCAAACCATCTTCTGCCTCTTCCCTTGAGAAAACG GGCATCTCACGTACCCCCATCTGAGACCTCTTGGAAAAAAAAAATCCCGTGTATTCTGGAGATGTGAGAATTCACCCAAAATTCTTAAAA CATTGGAGAATAGCTTGTTATAAAATAAAAGTGGGGGTAAAAAGAAGGTGGTTTTCCCCACATCCCTTTGCATTGAATAAGAGACCTAGT TCTTTGCGTTTGTGCAATAACTCTTTGCTGCTTGCCTTGAGAGCGGGTAGCACCACGCTCCTGTCCAGACTACTAACAGCACAAGACGCA CTCACAGGGTGGCGGAATCTTCCGGAAAACTCTCTATAAGCTCAGCTCCCCCCACCCCACCCCCACTCTAGCGTTTTGTCACGTCTTACA TTTTAGCAGTATTTTATATTTTCTGTAACGCACCAAGTCTTAGATCTTTCTAGAGCTTGTTTGTTCATCCTCACAATCACAGATTTTTTT CTCCAATCCTCACAGAGACCCAATTGACCAAAAAAGAAAAAAGGAAAAAAAAAAAGTCGTCTTTTTTTTTTTTTTTTGTACAAATCGCTT TGAGATGCCTCTGGTGTGTTGCTGTGTGACATCTCTCTGGTAACATTTTATTTCTTGCTATTTGTTTTTCTACATTAAGAGTCAAAGTTG ACCTGGCTGGCGTGGGGGTGGGGGAGGCACCCGTCGGCCCCTTGGTGTTGTCCCTCTGTCTTTGGTTAGCCATACGATGTTTGTTCTCAG CACTGTACAACGGTCCCTATATAATACGGAGAAGCAATATCACTGTATGAGACTCACACCATGTATTATTATTCACTAGCACCCTAGGTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000425244_chr7_101801840_+_3238nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGACGCTGTGCAGAGCTGCAAGTCCGTATCAC TGAGGCTGTGGCCACAGCCACTGAGCAGAGAGAGCTGATCGCCCGCCTGGAGCAGGACCTGAGCATCATTCAGTCCATCCAGCGGCCCGA TGCCGAGGGTGCCGCTGAGCACCGCCTGGAGAAGATCCCAGAGCCCATCAAAGAGGCCACTGCCCTATTCTACGGACCTGCAGCACCAGC CAGCGGTGCCCTCCCAGAGGGCCAGGTGGATTCACTGCTTTCCATCATCTCCAGCCAGAGGGAGCGCTTCCGTGCCCGGAACCAGGAGCT TGAGGCCGAGAACCGCCTGGCCCAGCACACCCTCCAGGCCCTGCAGAGTGAGCTGGACAGCCTGCGCGCCGACAACATCAAGCTCTTTGA GAAGATCAAGTTCCTGCAGAGCTACCCTGGCCGGGGCAGCGGCAGTGATGACACGGAGCTGCGGTACTCGTCCCAGTACGAGGAGCGCCT GGACCCCTTCTCCTCCTTCAGCAAGCGGGAGCGGCAGAGGAAGTACCTGAGCTTGAGTCCCTGGGACAAGGCCACCCTCAGCATGGGGCG TCTGGTTCTCTCCAACAAGATGGCGCGCACCATCGGCTTCTTCTACACACTGTTCCTGCACTGCCTGGTCTTCCTGGTGCTCTACAAGCT GGCATGGAGCGAGAGCATGGAGAGGGACTGTGCCACCTTCTGCGCCAAGAAGTTCGCTGACCACCTGCACAAGTTCCACGAGAATGACAA CGGGGCTGCGGCTGGTGACTTGTGGCAGTGATACCCCGGGGCCTCCCCCGTGACAGTGACGGCTGCGCCTCCACCCCGACTGCTCAGTGC ATCTAATCACTTAGACTCCCCTGAAGAATCCCCCATGGAAACTGCCCTTATCCGCTGTCCAGCAGCTGCCAGAGGCCCCAGGTCACCTCG GGTCCCCTTGAAAGAATGTCTCGGTCACATCAGGCCCGCTAGGTCCAGAGAGCGAGCCCCCAATGCCCGGCCAGGCTAAGCCGCAGAGAC CCTCTCAGCCCCCACCTCAGGTTAGGGCTCTGCCCGCAGCCTGACCTCTAGCCCTGGTGGCAGAGGTCCCTCAGCTGCGAGGCTAATTGG GTGACCACCGATTCCAGCTGCGGTTAATCCAGCTTGGGCCTGTCTGCACTGCGATCCTCTTGGGCTCTCCTAGGATCCCCCCATGCCCCG TAAGAGGTGGAAGACGCTTCCTTCCAGGACAGCAGGCTTTGAGTCCAGCACCCCCAGCCTGCCTTTGCCACCAGCCCCACCCTGCAGAGT ATATGAGGCTTGACAGAGTCTGCCCCCTCCCCCACTGCACCCCAAGAGAGAGAGCCCCAGCCAGCGGAACAGTTTCTATTACCCCCTCCC TGCCCCCAGACCCATGTGATTTCTGCTTTCTTCTTTAGCAAGATATTCTGGTTTCTAGATAAGGAAGAGTCTCTAATGAGCCCCCGAGCC CCAGTCTCTTCAGACTCATGGATTGGTCTGAGGGGTCTGAACGTCTCCTAGCCAATCAGAACTGGCTGTGGACCACCCTAGCACGGCCAC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000292535_chr7_101801840_+_14076nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGGTCAGCCAGGAGGAAAGGGAAAGACCAGCC TGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCGGGGGAGCAGGCTTCCAATACTAATGGTAC ACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCCAGCCTACCCCTGGCTTCTACAGGAAAATT TGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAGGAAGCCGGAAGCACAAGCATGATTTTTTC AACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCA GTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAA TATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAA ACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGG CAGACAAAGAGAGAATCCAGGCCAGAGCCTGAACAGACTATTTCAGGAAGTACCGAAACGAAGAAATGGGTCTGAAGGTAACATCACCAC CCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCCAAGAGGGAGCTCCAAGTGCAGAAAACTGC AGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGA GGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCAC CTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCT GCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAG ACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTC CGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAG TCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGAC CGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCC CCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAA GAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATG GAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCA GGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAA GACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTG TCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCT CTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGT GCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCC CAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCT GATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGT CGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGC GCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGT CATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGC CAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGG CAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTC GGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGC GACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGC GCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGC CCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGCCGCCAGCCGGGA GGAACCTATCGAATGGGAGTTCTGAGGGGCCGCGGCCCTGGGGCGGGCAGCCAGGCTGGGCCGCAAGGGCCTGGACGGGGTCGGACGGGG CAGGCGCTGCGGACACCGTGGCCTGGGCTTGGCCCGCGGCCTGCACCGACCCCGGGCCGGACCTGAGCCCGCAGCCCAGACCCCCTCCAC GGTCCGCGGCCTGCACCGACCCGAGGCCCAGATCCAAGGCCGCGGCCCAGACCCACTCTGCGGCCCGGGCCGACCCTGCGGCCTCCACCA ACCCCGCGGCCCAGACCCAGCCCGCGGCCTGGACCCCTGGACCGCTTTGCGCACTTACCGCCCTGCGGGCCACAGGGCAAAATCGCCATA GGCCAAGGTGCATATAGAAAACAAAGGAGCATTAAGCCCAATCTATGTCGTGTTTTCAAGGAAGAAAACGGAAATGTGTGGTCGAGCTTT TTTGTACCCTGAAGTGTTTTTTTTATTGCCCTAAGTGATTTCCACAGGTTCTGGAATAACTCTTACAGCTTTGCCTTGTGTCCTCCTGTT CCGTGTGGGCTTTAAAAGAAAAAAAATCAAACCCACATATTAAAAGGGGGCTTTTTATCTGCCATCTAATGGCTTCAGAGCGATAATACA CTATTATCTTCTTAAACCAGGAAAAAATAAAAGGGGGGGTGGGATTTTTCAGAAAAATTAAAAAAGAAAGTTTTTGTAGCTGTTCAGTTG CCACTAAGAGATTGCACAGTCAAAACGACTCTAAACACACTAGTTTGGATTCCTAAATATTTTCAAGAAAAGAATCTTCTCGTTTGAAAC TTTGAATTAAAATAAAACACATTTACTCCACATATTTTTTAACAAAAAGAAAACGTCACATCAGGAAACTCTGATTTTGTGGTAGCTGAC ATAGTGTTTTCTTGTACGTGAATAGAATCCTGACATGTAGTGCACATTGATGTATAGCTTTAACTGACCCTGGGTTTTGCAGACCAGGGT TTGTTTAATACACTCCATTCTAGGCCAAATCAGGACAAAAAAAAGAAAAAAAAAGAAAAAAAAAAAAGAAAAGATCCGAATCTAGGTATT TTATAATCTGCTTTTTAACCTCTAACCGCAGAGCACGCTGATCAGACCTCATATCTTGGAGGTTTAGGAGACAAGTTAGAACTGTAGCAT GTACCTGTTAATTTTGTTTAATTTATGGTGTCTCAATCTGTCTGTGCGTCTGCACGTGTGCAAGCATTGAAAGAAAGGAGAGAGTAGTCC GGGCGAGCACAGCAGGCAGTTCCAGGGCCAGACGGGCCCATCCCCAAGTAGATAGCAGTCTACGGATCTCTCTCTGGCACAGAAGGCACC TCACCTCACACCACTCTCCTGGATACCTGATGAACTGAGCCCTCCCAGGGGAAGACACTCCCCAGGCCTGGGCAGGGCTTACACGCGCAC TCTCTCTCTTCTTTCCCTTTTTCTTCCCACCGCAAGCACTGATGACCCTGTTGAACTCGTGGGAAACTTCCTTTCTCTGCAGGAGAGAGA ACGTGGCATTCTGGGCTCCCCACTCCCATCCCTGTAGAAATGGCCCAAACTCACACCAAAACGTGGATGCTCTTCAACTTCCAAACCTAC CATTTGCCCTTCTTTCATTTCGCCTCTTAGTTCTTTTTATGCACAGTTTTAGGGCAGTCTAAGTACAAACTGAAAGTCTAACTTGTCTCT GATTCCTCCCTTGTCTATGTGTATATGCGTGAGAATAGAGGCGGGTGAGAGTGTGCGTGCGTGTGCGTGTGTGCAATTTTATACGTCTGT GTATTTTCTTAAGTACCTGTGCACACGTAGAGTGCATTACTGCCACCTTTTTCAATAAGCTGTTTTATCAGTTACGGCTTCTACAAGTTT GCTAATTTAGACTTCTTTATTGCCATATCTTTAAACTAACAATAGATGATTTCGGTATATATATATATTTTTTTTTGCTTATTTATAGGT GCTGTATTTTATTATCTGATTGTTAGGAAGGGATGAAAGGGGCAAATATTCTTTAGAGGGATAGACTGCCGGCAGTATTGGGTATAATTT ACAAGATGTAGTTGTCATACTGTATATTACTGATTGAAAACTTTTTGACCGTATTGTGTATCATTGAAACCTTTGTCTTAGGTCAACATC TTTGGATGACATTTTAATGGTGCATTCATTATTTCTTAAGTTTAATTAATATTACTTTTTTTTTTATTTGGGGGGTGGGAGGGAGTTATA ATTTTAAAGGTATGCTCTGGCTGTTCCACCTCCGTGTGCTTGTTAATTAACTTGTAGGACTTTGACTGTAAGATGTGAAACCACGTTTCT TGCATGATGTTTTAGAGATTATTTCATTTACAGTCTTTTAACCTGCAGCTGCAGCACTTAGTTCACGTTTTCACAAATTTCAAGAGTCAC TACACTAAAGACAATGCCTTTTCATGAATAAGAAGTTTTCAGAAGGCTCTAGGGGGCTGGGAGGCAGGCTGTTCGTTTGTCTTTTGTTGG GGGTATCATTTCTGAACTTGAAATCCAGTTCAGGGAGAAGAGAATTCAAAATTAGAGGAGCTTAAGGGGACACGGGTCAACATCTAGCTC GATTCAGGTGCATTGAGAAGAGTGAGTTCACATCGGTGACCCTTAGGACAGTGAGTGGCAGAGCCCTGACGACTGTGGTGTCCTCTCCAC AAAACCCTCAAGGGACTTTTGTCATCATGTGTGATGAATCTTTAAATATCGTCTAATTTTCATAAGAATGAAAAGAAGTTAACAGGAAAT AGTAGGCTAGGGTTTAGTTTTAAAGGCATGACTGTTATTTACAAAGGTGTTAAATCTGAGGAAATTGACAAATACAGATTTGTCCATTCT AGTGGCCAAACAGTAACAGTCTAAAATGCAGTCATTTTGACCCTCCCAAGCAATTTAGTCATATGTGTTGTTTTCTCTTTTCTGTTTTTA CTTCTTAGATTTTTAACTAGGTTACTGTTGGTTCCCATTCTGTCTTTTTTGCCAGACTTACATCTGGTGCCAGATACAATCAGTTGGTTA AATTTTGCTTGCAGTTCTGTGTATTTTTTTTCCTCTATTATTTATTTTTTTAAAAAAAATAGAGATCCTAACCTTAGATCTTTGATGTGA AGCTAGCACTGTCTGTAATACTTCTAAGAGCTGCCACTAAAATAATACAGCAATCCGTGGCCAGGGGAGCACCCCCTCCTGGTTGGGCCC CTCAGTTGGAGTCTAAGGGTTAATCTCTCATCTTGCTAAGCAGTATTCAAGTGCCTTGAACAGTGTCCCCTCGGCATGGCTCCCCTTCAG CAGGCTGGCATTCCAAGCAGTGGCCCCCGCAGGCAGCCGACCCCCTTCCTCTTCACGCTCTATGAGTTTAAAAAGCTGATTTGTACCTCT CCCCTGGGGGAAACGGTTCCATATAAAACACTAACACTTAATTACAAGCTCCATTATGCCATTTTAAATGGCTTCTTTTTGTTAATTGGA GGCATTGTTCATAACTTAAGGCTTTTGCCATTAACTTAGCTGGCTAAGCAGAGGCTCGGGGTAAAATCAGTGTTTGCATTTAGCCTCTTG ACCCGGAGTTCCGGCCCAAGCTCCCTTGTGATAGCCGAGATGGCAGGTGTGTGAGTTCTGTCCTAGACCTGTGCCCAACTCACTTCCACC CCAGAGGAGTCTTCTGTCCTCCTCCCCAACCCCCGAGCTCCCTGGTAACCTCCTCTTGAACTTCTGTATCAGTGAAGACATCTGTGGTTT CTGCTCACCAGACCTCTCTTTAGAAAGGGTTATCAGAGCCATGGAGCTTAGCTCAATTGGATTCTTCTAGACGATCTTAGGAGGCATCTT GGCATGAGGCAGCTTCTAAGCGTCTCCTGGGACAGGATTGGGGTGACAGCCCAGGGATGCATGCATGGGAGAACTCTCTGAGAAATGCCA GGATCGTGGCTCACAGGGACCCACCATCAAAACCTGCTACTTTGTGCAAGTAATTGAGGCAAAAGATACCAGTCGACAGCCTCCCTGGGG TAGATCCCTTGTACCTCCAAAGTACAAATACCTCCCTGCTCAGTTTCCTTCCTGTCGCCATCTTTGTTTTCTTCCCATTGAAAAACCATC CTGTCTGATGTGGACGTTCAGGTCTGCTGGTTGGCGGTCCGGGCCCAGAGTGCAGCAGAGCTCTGGGTTAAATATTCCTTTCTGGCCACC GCCCAAGCCCAGGTGGCCAGCTCTCATACCCCATCTCCCTCCTTGGCCAGGGCCAGCATCAGGCGTGCAGCTCATGACCAGTTTACACAG GCTGCAAAGAGATCGCTGTGGGCCTCGGCTGACTACTTTAAGATTATGCCACAGCCAGGCCCTAAAAAGAGAGGGGAACAGGAGTCCCCA GGTGAGCTCTCTGACGGGCAGGTGCCTTCCCGACTAAGGTTGGACTGGATGACTTTGTTCCTCCTGCATGCATGTCCTTTGATGCAAGGG TGATCAATGAACTCTGTTGACATTCTATGCAATGTTTTTCATTCCTCTGATTTTAGCAAAGCAAATCTTACTGAAAAATAGCAGAGCCAG GGGAACAGACGCATGTCCTTCTGGGAGTCACACAAAAGCAGAGAGATTTTGAACTGAGGGGCGACAGCCTTTGCCTTAAATGCAGTATGA CAGGCGCTTCTTGGCAGACCAGTAAAAACAAAAGCCCATAGACCTTACTCATCCCAAGGCCGACAAGCCAGCTGTACAGGGCGAGATGTA GCAACACGGGGCATGAGCGGTGGGCGTGCTGGGCTATTTGCTGTGGTACTTTAGGCTGGAGGTTTGGCTCCTGTGCTGCCGGTGGGGGGC CCTGTCCCTCCCCAGATGTCCTCCCTCTTCTTCACACTCCTCATTGTCCCTTCTACCTCACTAACCTGTCTTCTCCATCTGATGTCACCC AGAACCACACCCCACAGAACTGTGAGGCACGTGGGCTGGAGAGAGCAGAAAAGCTGCCAGCGCAGCAGACACGAACATCCCTCTGCCTGG TGGGCCGGCTTTGTGTGTCTCTCCTTTTGTGAGCGCAACACGGACAAACAGCTGTGCTCTGCAAGGCACACGGATGTTTCCCTTCCACCT GTTCCCAAAGCTCCAGCAGCTGTTTCTTTTGCAGGCAGGGCGTGGTCTCGGGGCTCCGAGGGTCTTGTCTTTGGTCCGCCTTCCTTTCTG TCCAGTCCTGCTCAGCTGTTAAGATCCATCATGGCCATTATCCTTGTCCCGGACTGCCCCAAAGTTCCCAGCTGGCTTTGGGGAACACTG TAGCTCTTGGGTGTCTCTTGTCTCTGGCATGGTTTTAGCGTCACTGCGAACACTCCTTTGCAAACATCAAACATCTCAAAGACGGAAAAG GATAGATGGCTTCCTCCAGCCTACACGCCCCGTCCACAGTGGCATCACCCTCTTATCCCAAAAGAATATGCCAGTTCCCATCCAGCACCG AAGAAAATCAGCTCCTGGGGCTGGTGGTTGGAGGTGGGTCTGTCCACTGTGGGGGCCAAAGTGTTCCCCTGCTGGAGACAGTTTGCAAGT AAGAACCTAAGGATGGGGACAGCATCCTGTGCTTGGGCATTGACCAGCCAAAGCTCACATTTAGAAAGCCCTCAGTGCTTCTGTGGTTTC ACCTGGGCATCGACGACATTAGGGAAGCCTTTGTGACCACAAGGGCAGGGCTTGTGCCCTGAGTGGCGAGGTGGTGACCTGAGGCCAGTG TGATGTGGTTGGATCTCAGCGTGTACTGAATGCCAGTCTGGCCGGCACACTCGAACGCTAAGAGAATGGTCCAATTTGATGATCTTATTT CTATTTCGATCAGGTTTTGACTTTTTGTAGATGAAAACTACCAGGGAAAAGGGGAAGCAGGTACCCAATAAAGTTTAGAAAGATCCAGTC TGTGAAACCCTTAGAGATGGGCTGAAAGTTAAGTCCACCAACCCTTGGGCTTAATCAGGACGGAAGAGGAGGGGGTGTGGGGGGCAGAGC GTAAAACAAGCCCCAGCCCTACTCCCGGCCCCCCAGCCCAGTCTTCCCAATCCCAGAGGCCCCGGCGGCCTGTGCTCCTCACCACCCTGG TCAGGGGAATAGAAGGAAATGCAATTTCCGCCTGTCTGCCCGACTTCCAAAAACTGCCTCCTCCTGCCCAGGCCTCTCCCACCACCACCT TCCCTCCAAAGATAACCGTGTCCATGCCATCCGTGGCATCATCTCGAGTTTTCATTTTTGGATGAAGTGACATTTAGCTTTAACAAGACA TTTCCAAAGCGCCTAGTCTCCTCCAAAATGCTAACTTTAAAAGTTGGGCATTGTAGGCGAAAAATCCCAAAAAAAAAAAAAGACAAAAAA AAAAGGCTGGCGAGAGAAAGACATTTGGCTATGCATAAATGTGCACTTCCCCCATGCCCCCGTTCTTAAACTCTTAAGATGCCTTTGAGT TGCTTTTCATGAATCCTTTTAGTTTACCCGATAATGTTAAGAAAGCATTAGTCTACGTTACTGTAATTTCTGTAGTGTTTACGCTTTAAT TTCTACCACAAAATATGCTATATGCTATGTATCAAGCTTTCTGTAATCAGAAAGAAAAGGTGCCTTATATCCCAATGTCACGGCTACATC CCTATGGAAATTAATCAGAAGCACAGTGTGTACGGAAGCATTGGGACTTCTGCTGGTGAAACAAGAGACCATTCAGCAAGACACATTGAA GTGGCACGGAGCTGCTTTTGTTTTATAATTCTTTTTTCCCCCCTTTTCCTTCTTCTTTTTTATTATTTTATTATTTTTTTTGTACTTTGC TTTAAACGGAAAGCACTTAAATAGATGACTATGTGTAAAAGCTCTGTGCAATTGAAATCATTTTTCTTCATTTTAAAAAAATAACGTATT GCACACCAAATGAACTCAAAGTAAGCTTTAGACCAGGACGATTCAGGTTATGAATGAGTTTGTTCACTGTAGTTCCGTTTGTTCATGAAC CGAAGGGAAAACAGGCCTCCCCGACTCCCTCCAGTCTCCCAGCCTGCCTCTTGGTGACCACTGTGCTGGGCGTGCAGGGCCCGCGGGCTC TGGCCGGAGCCGCTGGCCTGACGAGGCAGGATAGGGAGTATCCGTGATTCAGAAGCTGAGACCCTTCCCCAGTGTCTGAGGCCACAGCCA TCCCTTCCAGCACTTAATCTTGTCTTGTTGAAATGGACTGACTGCTACTGACCTGCCGGCGTGCGTGAGGGTGATTATAAAAGGATGTTT CCTTGAGAAAAAAAAAATTATTTCTATCCTCTTCTATTTATTATTAGGTTAATCATTTAAGTACTTATCAGGAGTGTATTGTTATTTTGT GTTTTGTTGTCATAAATGCTTTTTGCTGTCACTCTAGTGGTTACTATCCTCTGCCTTCCTCTCCTCCCCTACTCCCCCAGAGAACCAAGG CGTCTGGGGGATTGACTGGGGGGCAGAGGGGGTTTCCCCAGCAAAATCAAACACCTGTCTCCAGAGTAGCCACTCAAAAACTGGTGGTCT CTATGTGTCTAACTTTTTAAATGAGAGTGTTTATGAACAAAAAAATTTACCAACGTGTGAGGGAGTTGCTGAGTTGAAGAATGCTCGCTT GAGGAGCTTCAGAGGAATCTTAGCAAAGCCAAGTTCAGTTCCCCAAAGCCTCCTAGAGCCTCTGGTAAGACTTCTGGGTTCATGAAGTTT CGGCGAGCCGTGGTCAGAGAGGGCGCGGTGGCCTGGCCAAGACTTTACCTCCAAGCGAGAGAGTGATTTCTTGCAAGGCCCGCATGGGTT GATACGTTTTGGTTGGTTTTTTGTTGTTGTTTTTCTTGCGTACAAAGTTGGTCAAAACCATCTTTCAAAGCAACAGTGTTTTGTAGTACC AGGCTGTGGCTTGAGGGCTCACCTAGGAGATCATAGGCAGAGGGCCCCTTTCCCCTATAGGTGGTTCAACGTGGAGGAAGGTTGGGTGTG GAGATTGCTTGCTGTGGCCCCAAGCTCAGCCAGCAGGACACCCAGTTGTTGCCAATCAGGTGTGAAGGTGAGGCGCCCTGCCTTGATCCC ATGGGCCCAGCAGAAGGAAACTTACCCCAGGCCAAGGCAAGGGCCCTGCTCACCCCAAGGTAGGCTGGGAAGAGCATCTCTTTCCATATC ATCACCTCCCCTTCTCCAAGATTGCCGGGGGCCCTGATTTTGTTCTCTCTTTGAAAGAAACCCTCCACCGAAACAATGGTCCCCATCTCC CCAGAAGCCTTTTTTTTTTTCATTTTTCTCTAATTAGTCTATGCATTTCTCTCTCTCAAACCATCTTCTGCCTCTTCCCTTGAGAAAACG GGCATCTCACGTACCCCCATCTGAGACCTCTTGGAAAAAAAAAATCCCGTGTATTCTGGAGATGTGAGAATTCACCCAAAATTCTTAAAA CATTGGAGAATAGCTTGTTATAAAATAAAAGTGGGGGTAAAAAGAAGGTGGTTTTCCCCACATCCCTTTGCATTGAATAAGAGACCTAGT TCTTTGCGTTTGTGCAATAACTCTTTGCTGCTTGCCTTGAGAGCGGGTAGCACCACGCTCCTGTCCAGACTACTAACAGCACAAGACGCA CTCACAGGGTGGCGGAATCTTCCGGAAAACTCTCTATAAGCTCAGCTCCCCCCACCCCACCCCCACTCTAGCGTTTTGTCACGTCTTACA TTTTAGCAGTATTTTATATTTTCTGTAACGCACCAAGTCTTAGATCTTTCTAGAGCTTGTTTGTTCATCCTCACAATCACAGATTTTTTT CTCCAATCCTCACAGAGACCCAATTGACCAAAAAAGAAAAAAGGAAAAAAAAAAAGTCGTCTTTTTTTTTTTTTTTTGTACAAATCGCTT TGAGATGCCTCTGGTGTGTTGCTGTGTGACATCTCTCTGGTAACATTTTATTTCTTGCTATTTGTTTTTCTACATTAAGAGTCAAAGTTG ACCTGGCTGGCGTGGGGGTGGGGGAGGCACCCGTCGGCCCCTTGGTGTTGTCCCTCTGTCTTTGGTTAGCCATACGATGTTTGTTCTCAG CACTGTACAACGGTCCCTATATAATACGGAGAAGCAATATCACTGTATGAGACTCACACCATGTATTATTATTCACTAGCACCCTAGGTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000549414_chr7_101801840_+_4819nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGGTCAGCCAGGAGGAAAGGGAAAGACCAGCC TGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCGGGGGAGCAGGCTTCCAATACTAATGGTAC ACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCCAGCCTACCCCTGGCTTCTACAGGAAAATT TGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAGGAAGCCGGAAGCACAAGCATGATTTTTTC AACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCA GTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAA TATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAA ACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGG CAGACAAAGAGGTAACATCACCACCCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGCCATCAAGTCCATCCTAGAGCAAGCCAAGAG GGAGCTCCAAGTGCAGAAAACTGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCT GCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCAT CCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGC TCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGC CGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCC GGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGG CAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTC CCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTC CAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCG GCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGA CATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCT AGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTG TGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCT GACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTC CCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGG CATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTC TGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAA CGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAG CCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGT GCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCA GCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGC CGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGG CGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGC GGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGG GCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGA GGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTT CGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000556210_chr7_101801840_+_4411nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGTCCATACAGCACAAACTCCATATCTTCCCA AAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGA GATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGG ACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGAT GAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGCAGAGCCGGCCCAGCCTTCCTCCGC ATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCC TGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAG CTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAA GGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCG CAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAAC GGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTC AGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACC ACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGA GGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTT CGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCG AGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCT CCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGC CCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGA CAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCAT CCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCA GCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCT GAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAA GAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGC CAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAA GCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAG GTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAG CGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAA GTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGC CCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGC CCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAG CAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCT GCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGCCGCCAGCCGGGAGGAACCTATCGAATGGGAGTTCTG >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000550008_chr7_101801840_+_4717nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGGTCAGCCAGGAGGAAAGGGAAAGACCAGCC TGAAAGTCGGCGCCCGGGATCTTTGCCGGCCCCCCCTCCTTCTCAGTTGCCCCGCAACCCGGGGGAGCAGGCTTCCAATACTAATGGTAC ACACCAGTTCTCACCAGCGGGGTTAAGTCAAGACTTTTTCAGCTCATCCCTGGCAAGCCCCAGCCTACCCCTGGCTTCTACAGGAAAATT TGCACTAAACTCTCTTCTCCAGCGGCAGCTAATGCAGTCCTTCTACTCCAAGGCTATGCAGGAAGCCGGAAGCACAAGCATGATTTTTTC AACAGGTCCATACAGCACAAACTCCATATCTTCCCAAAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCA GTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGAGATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAA TATCGGACAACGTATTTTCGGACATTATGTGTTGGGACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAA ACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGATGAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGG CAGACAAAGAGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGGGAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCG CCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCAGGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAA GCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCTCGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGG TGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGACGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACA AGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTGGAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAA TGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAAAGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCG GGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAAGGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGA GCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCCCCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAA GCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTACCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGA AAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGTGCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCG ACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCATCCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGT TCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGACATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGA AAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCCGATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGT CCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACCAGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAAC CCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGTAGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCG GGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGGGGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCT CCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGAGCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAA TGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACATGAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGA ACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCCCCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGA GGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTCACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAA AACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCGCAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGG CCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGCGCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCAC TGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGAGGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGA GCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGACCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAG CCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGCCGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGC CCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCCCCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGA GGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAAGGCCGCGAACTTGAACAGCATCATCCACCGCCTGGAGAAGGC >In-frame_BRAF_ENST00000288602_chr7_140500162_-_CUX1_ENST00000546411_chr7_101801840_+_4579nt CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGGCCGACGAGATTGAAATGATCATGACGGACCTTGAAAG GGCAAACCAGAGGGCAGAGGTGGCTCAGAGAGAGGCGGAGACCTTAAGGGAACAGCTCTCATCGGCCAATCACTCCCTCCAGCTGGCCTC ACAGATCCAGAAGGCACCAGACGTGGAGCAGGCCATAGAGGTGCTGACCCGCTCCAGCCTAGAAGTTGAGTTGGCCGCCAAGGAGCGGGA GATCGCACAGCTGGTGGAGGACGTGCAGAGACTCCAGGCCAGCCTCACCAAGCTGCGGGAGAATTCGGCCAGCCAGATCTCACAGCTTGA GCAGCAGCTGAGCGCCAAAAACAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTGACTATGAAGAGGTGAAGAAAGAGCT GAACATTCTGAAGTCCATGGAGTTTGCACCGTCCGAGGGCGCTGGGACACAGGATGCGGCCAAGCCCCTGGAGGTGCTGTTGCTGGAGAA GAACCGCTCGCTGCAGTCCGAGAACGCCGCGCTGCGCATCTCCAACAGCGACCTGAGCGGTCCATACAGCACAAACTCCATATCTTCCCA AAGTCCATTACAACAAAGCCCAGATGTCAATGGCATGGCCCCATCCCCCAGCCAGTCAGAAAGTGCTGGGAGCGTCTCCGAGGGCGAGGA GATGGACACTGCAGAAATCGCCCGGCAGGTCAAAGAGCAGCTGATTAAGCACAATATCGGACAACGTATTTTCGGACATTATGTGTTGGG ACTGTCTCAAGGGTCCGTGAGCGAGATTCTGGCCCGGCCCAAGCCATGGAATAAACTGACTGTTCGTGGCAAGGAGCCATTTCACAAGAT GAAACAGTTCCTCTCCGATGAGCAGAACATCCTGGCCCTCCGTAGCATCCAAGGCAGACAAAGAGAGAATCCAGGCCAGAGCCTGAACAG ACTATTTCAGGAAGTACCGAAACGAAGAAATGGGTCTGAAGGTAACATCACCACCCGGATCCGAGCCTCGGAGACTGGCTCTGATGAAGC CATCAAGTCCATCCTAGAGCAAGCCAAGAGGGAGCTCCAAGTGCAGAAAACTGCAGAGCCGGCCCAGCCTTCCTCCGCATCCGGCAGCGG GAACTCTGATGACGCCATCCGCTCCATCCTGCAGCAAGCCCGCCGGGAGATGGAGGCCCAGCAGGCTGCCCTCGACCCTGCCTTAAAGCA GGCACCACTGTCCCAGAGTGACATCACCATCCTCACCCCCAAGCTTCTGTCCACCTCGCCCATGCCCACCGTGTCCAGCTACCCACCTCT CGCCATCTCCCTGAAGAAGCCCTCCGCAGCTCCTGAGGCCGGTGCCTCTGCTCTGCCGAACCCCCCGGCCCTCAAAAAGGAGGCCCAGGA CGCCCCCGGGCTGGACCCCCAGGGAGCAGCCGATTGTGCACAAGGGGTCCTGAGACAGGTGAAAAATGAGGTGGGCCGCAGCGGTGCCTG GAAGGACCACTGGTGGAGCGCGGTGCAGCCGGAGAGAAGAAATGCCGCCTCCTCCGAGGAGGCCAAGGCCGAAGAAACGGGCGGCGGGAA AGAGAAGGGCAGCGGTGGCAGCGGAGGTGGCAGCCAGCCTCGGGCCGAGCGCAGTCAGCTCCAGGGACCCTCGTCGTCAGAGTACTGGAA GGAGTGGCCCAGCGCTGAGTCCCCATACTCCCAGAGCTCAGAGCTGAGTCTGACCGGGGCCAGCCGCAGCGAGACACCACAGAACAGCCC CCTGCCATCCTCCCCGATCGTGCCCATGTCCAAGCCCACCAAGCCCTCGGTCCCCCCGCTGACCCCCGAGCAGTACGAGGTCTACATGTA CCAGGAGGTGGACACCATCGAGCTCACCCGGCAGGTTAAGGAAAAGCTGGCCAAGAACGGCATCTGCCAGAGAATCTTCGGGGAGAAGGT GCTGGGCCTGTCCCAGGGCAGCGTCAGCGACATGCTGTCCCGACCGAAGCCATGGAGCAAGCTGACGCAGAAAGGCCGAGAACCCTTCAT CCGGATGCAGCTCTGGCTGAACGGCGAGCTAGGCCAGGGTGTTCTACCCGTCCAGGGCCAGCAGCAAGGGCCAGTCCTCCACTCCGTGAC ATCGCTCCAGGACCCGCTGCAGCAGGGCTGTGTGAGCTCAGAAAGCACTCCAAAGACCTCCGCCAGCTGCAGCCCTGCCCCTGAGTCCCC GATGAGTTCCAGTGAGTCGGTGAAGAGCCTGACCGAGCTGGTCCAGCAGCCCTGTCCCCCCATCGAGGCGAGCAAGGACAGCAAGCCACC AGAGCCCAGTGACCCGCCAGCATCCGACTCCCAGCCCACAACCCCGCTGCCTCTCTCCGGACACTCGGCCCTCAGCATCCAAGAATTAGT AGCCATGTCCCCGGAGCTGGACACCTACGGCATAACCAAGCGGGTGAAGGAGGTGCTGACGGACAACAACCTCGGCCAGCGCTTATTTGG GGAGACCATCTTAGGGCTCACCCAAGGCTCTGTCTCTGACCTCCTTGCCCGCCCCAAACCCTGGCATAAGCTCAGTCTGAAAGGACGAGA GCCCTTCGTCCGGATGCAGCTGTGGCTGAACGACCCCAACAATGTGGAGAAGCTGATGGACATGAAACGGATGGAGAAGAAAGCCTACAT GAAGCGGCGGCACAGCTCAGTCAGTGACAGCCAGCCCTGCGAACCGCCCTCTGTCGGCACCGAGTACAGCCAGGGCGCCAGCCCCCAGCC CCAGCACCAGCTGAAGAAACCCCGGGTGGTGCTGGCTCCGGAGGAGAAGGAGGCGCTGAAACGAGCGTATCAGCAAAAGCCATACCCGTC ACCAAAAACCATCGAAGACCTCGCCACCCAGCTCAACCTGAAAACCAGCACCGTCATCAACTGGTTCCACAACTACAGGTCTCGGATCCG CAGAGAACTGTTCATTGAGGAAATTCAGGCCGGGAGTCAGGGCCAGGCGGGCGCCAGCGACTCACCCTCGGCCCGCAGCGGCCGGGCGGC GCCCAGCTCGGAGGGCGACAGCTGCGACGGCGTGGAGGCCACTGAGGGCCCAGGCAGCGCCGACACCGAGGAGCCCAAGTCTCAGGGAGA GGCCGAGCGGGAGGAGGTGCCGCGGCCGGCGGAGCAGACGGAGCCGCCGCCCTCGGGGACCCCGGGCCCGGACGACGCCCGCGACGACGA CCACGAGGGAGGCCCCGTGGAAGGCCCGGGGCCCCTGCCCAGCCCCGCCTCCGCGACCGCCACCGCCGCGCCCGCGGCCCCCGAGGACGC CGCTACCTCAGCCGCCGCCGCGCCGGGGGAGGGCCCCGCGGCCCCGAGCTCCGCGCCGCCGCCCAGCAACAGCAGCAGCAGCAGCGCCCC CCGCAGGCCCAGCTCGCTGCAGAGCCTTTTCGGCCTCCCCGAGGCCGCGGGCGCCCGGGACTCGCGCGACAACCCCCTGCGCAAGAAGAA |
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FusionGenePPI for BRAF_CUX1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BRAF | YWHAB, YWHAG, YWHAQ, YWHAZ, SFN, HRAS, AKT1, MAPK3, RAP1GAP, RAF1, MRAS, RAP1A, PAK2, TERF1, CCDC88A, NEDD4L, MAP2K1, RNF149, KSR1, BRAP, PRKCE, RPS6KB2, HSP90AA1, BRAF, YWHAE, HSPA5, MAP2K2, HSPA1A, HSPA8, YWHAH, HSPA9, ARAF, CDC37, HSP90AB1, PHKB, LIMK1, IQGAP1, MAPK1, BAD, LIPF, MUS81, FBXW7, FGFR2, BRCA2, VHL, FNTA, HDAC2, PIK3CA, EGFR, PTEN, FNIP1, FNIP2, RAB3GAP1, KRAS, KIAA0141, FKBPL, ARMCX3, KCNC4, RPTOR, CYLD, NRAS | CUX1 | RB1, CREBBP, KAT2B, BIN1, ELAC2, RECQL5, CDK7, CCNA1, CDK1, SATB1, TLE4, MAX, SOX2, KCND3, EHMT2, ECT2, TP53BP1, SUMO2, MAGEA10, HLA-DQA1, STX6, WDR83, PTH1R, GABRE, SLC39A4, NIT1, NTRK1, TACC3, SPATS2L, NFATC1, RBPJ, FOXD3, FOXE1, FOXG1, FOXJ2, GAN, FOXK2, FOXN1, FOXO1, FOXP1, FOXQ1, SLC39A12, EXT2, RAB30, LAMP1, POTEB3, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BRAF_CUX1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | BRAF | P15056 | DB08881 | Vemurafenib | Serine/threonine-protein kinase B-raf | small molecule | approved |
| Hgene | BRAF | P15056 | DB08896 | Regorafenib | Serine/threonine-protein kinase B-raf | small molecule | approved |
| Hgene | BRAF | P15056 | DB00398 | Sorafenib | Serine/threonine-protein kinase B-raf | small molecule | approved|investigational |
| Hgene | BRAF | P15056 | DB08912 | Dabrafenib | Serine/threonine-protein kinase B-raf | small molecule | approved|investigational |
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RelatedDiseases for BRAF_CUX1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | BRAF | C0025202 | melanoma | 21 | CTD_human |
| Hgene | BRAF | C1527249 | Colorectal Cancer | 8 | UNIPROT |
| Hgene | BRAF | C1275081 | Cardio-facio-cutaneous syndrome | 6 | CTD_human;ORPHANET;UNIPROT |
| Hgene | BRAF | C0009404 | Colorectal Neoplasms | 4 | CTD_human |
| Hgene | BRAF | C0040136 | Thyroid Neoplasm | 4 | CTD_human |
| Hgene | BRAF | C0024305 | Lymphoma, Non-Hodgkin | 3 | UNIPROT |
| Hgene | BRAF | C0684249 | Carcinoma of lung | 3 | UNIPROT |
| Hgene | BRAF | C3150970 | NOONAN SYNDROME 7 | 3 | CTD_human;UNIPROT |
| Hgene | BRAF | C0152013 | Adenocarcinoma of lung (disorder) | 2 | CTD_human |
| Hgene | BRAF | C0002448 | Ameloblastoma | 1 | CTD_human |
| Hgene | BRAF | C0004114 | Astrocytoma | 1 | CTD_human |
| Hgene | BRAF | C0010276 | Craniopharyngioma | 1 | CTD_human;ORPHANET |
| Hgene | BRAF | C0017638 | Glioma | 1 | CTD_human |
| Hgene | BRAF | C0022665 | Kidney Neoplasm | 1 | CTD_human |
| Hgene | BRAF | C0023903 | Liver neoplasms | 1 | CTD_human |
| Hgene | BRAF | C0024694 | Mandibular Neoplasms | 1 | CTD_human |
| Hgene | BRAF | C0028326 | Noonan Syndrome | 1 | CTD_human;ORPHANET |
| Hgene | BRAF | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | BRAF | C0036920 | Sezary Syndrome | 1 | CTD_human |
| Hgene | BRAF | C0079773 | Lymphoma, T-Cell, Cutaneous | 1 | CTD_human |
| Hgene | BRAF | C0206686 | Adrenocortical carcinoma | 1 | CTD_human |
| Hgene | BRAF | C0206754 | Neuroendocrine Tumors | 1 | CTD_human |
| Hgene | BRAF | C0238463 | Papillary thyroid carcinoma | 1 | CTD_human;ORPHANET |
| Hgene | BRAF | C0587248 | Costello syndrome (disorder) | 1 | CTD_human |
| Hgene | BRAF | C0596263 | Carcinogenesis | 1 | CTD_human |
| Hgene | BRAF | C0920269 | Microsatellite Instability | 1 | CTD_human |
| Hgene | BRAF | C2239176 | Liver carcinoma | 1 | CTD_human |
| Tgene | CUX1 | C0041696 | Unipolar Depression | 3 | PSYGENET |
| Tgene | CUX1 | C1269683 | Major Depressive Disorder | 3 | PSYGENET |
| Tgene | CUX1 | C0525045 | Mood Disorders | 1 | PSYGENET |
| Tgene | CUX1 | C0596263 | Carcinogenesis | 1 | CTD_human |
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