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Fusion gene ID: 43362 |
FusionGeneSummary for ZNF490_FARSA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF490_FARSA | Fusion gene ID: 43362 | Hgene | Tgene | Gene symbol | ZNF490 | FARSA | Gene ID | 57474 | 2193 |
| Gene name | zinc finger protein 490 | phenylalanyl-tRNA synthetase subunit alpha | |
| Synonyms | - | CML33|FARSL|FARSLA|FRSA|PheHA | |
| Cytomap | 19p13.2-p13.13 | 19p13.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 490 | phenylalanine--tRNA ligase alpha subunitpheRSphenylalanine tRNA ligase 1, alpha, cytoplasmicphenylalanine--tRNA ligase alpha chainphenylalanine-tRNA synthetase alpha-subunitphenylalanine-tRNA synthetase-like, alpha subunitphenylalanyl-tRNA synthetas | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9ULM2 | Q9Y285 | |
| Ensembl transtripts involved in fusion gene | ENST00000311437, ENST00000465656, | ENST00000588025, ENST00000423140, ENST00000314606, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ZNF490 [Title/Abstract] AND FARSA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FARSA | GO:0006432 | phenylalanyl-tRNA aminoacylation | 20223217 |
| Tgene | FARSA | GO:0051290 | protein heterotetramerization | 20223217 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-43-5670-01A | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000311437 | ENST00000588025 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| In-frame | ENST00000311437 | ENST00000423140 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| In-frame | ENST00000311437 | ENST00000314606 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| 5UTR-3CDS | ENST00000465656 | ENST00000588025 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| 5UTR-3CDS | ENST00000465656 | ENST00000423140 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
| 5UTR-3CDS | ENST00000465656 | ENST00000314606 | ZNF490 | chr19 | 12719972 | - | FARSA | chr19 | 13041563 | - |
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FusionProtFeatures for ZNF490_FARSA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF490 | FARSA |
| May be involved in transcriptional regulation. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >FARSA | chr19:12719972 | chr19:13041563 | ENST00000314606 | - | 0 | 13 | 372_374 | 49 | 509 | Region | L-phenylalanine binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 57_132 | 54 | 530 | Domain | KRAB |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 156_178 | 54 | 530 | Zinc finger | C2H2-type 1 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 194_216 | 54 | 530 | Zinc finger | C2H2-type 2 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 222_244 | 54 | 530 | Zinc finger | C2H2-type 3 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 250_272 | 54 | 530 | Zinc finger | C2H2-type 4 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 278_300 | 54 | 530 | Zinc finger | C2H2-type 5 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 306_328 | 54 | 530 | Zinc finger | C2H2-type 6 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 334_356 | 54 | 530 | Zinc finger | C2H2-type 7 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 362_384 | 54 | 530 | Zinc finger | C2H2-type 8 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 390_412 | 54 | 530 | Zinc finger | C2H2-type 9 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 418_440 | 54 | 530 | Zinc finger | C2H2-type 10 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 446_468 | 54 | 530 | Zinc finger | C2H2-type 11 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 474_496 | 54 | 530 | Zinc finger | C2H2-type 12 |
| Hgene | >ZNF490 | chr19:12719972 | chr19:13041563 | ENST00000311437 | - | 2 | 5 | 502_524 | 54 | 530 | Zinc finger | C2H2-type 13 |
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FusionGeneSequence for ZNF490_FARSA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000588025_chr19_13041563_-_514aa MRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIP PEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWV SKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQP QQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDR VFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000423140_chr19_13041563_-_483aa MRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIP PEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVGSWRDRP FKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRV KRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGH LMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRE >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000314606_chr19_13041563_-_514aa MRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIP PEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWV SKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQP QQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDR VFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000588025_chr19_13041563_-_1542nt ATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTCCAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACA GGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGCATCAAGACTCAAACTGTCATCGAGGCTGAACTT CGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGCAGCCATGAGGCCCGTGTGTTTCGAAGCATTCCC CCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTCAGCAAGGCCATGTCCAACAAGTGGATTCGGGTG GACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGATGAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGG GGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTGTTGGCTGAAGTGACTCTGAAGACCTACTGGGTG AGCAAAGGCAGTGCCTTTAGTACCAGCATCTCCAAGCAAGAGACAGAGCTGAGCCCAGAGATGATCTCCAGTGGCTCTTGGCGGGACCGG CCCTTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTTCACCCGCTGCTCAAGGTCCGCTCCCAGTTCCGA CAGATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGCTCCTTCTGGAACTTTGACGCCCTCTTCCAGCCC CAGCAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAGGCCCTGCAGCTCCCAATGGACTATGTCCAGCGG GTCAAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGGAAGCTGGACGAGGCCCGGAAAAACCTACTGCGA ACCCACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCCTTCACTCCGGTCAAGTACTTCTCCATCGACCGC GTATTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAGGGCGTGGTGGCGGATCATGGTCTCACCTTGGGC CACCTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGCTTCAAGCCAGCCTACAACCCATACACAGAGCCC AGCATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAACTCGGGGGTCTTCCGTCCAGAGATGCTGCTGCCC ATGGGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCAACGATGATCAAATATGGCATCAACAATATCCGG GAGCTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGCCTGGATGCCGAGCCGAGGCCCCCTCCCACACAG >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000423140_chr19_13041563_-_1449nt ATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTCCAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACA GGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGCATCAAGACTCAAACTGTCATCGAGGCTGAACTT CGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGCAGCCATGAGGCCCGTGTGTTTCGAAGCATTCCC CCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTCAGCAAGGCCATGTCCAACAAGTGGATTCGGGTG GACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGATGAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGG GGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTGTTGGCTGAAGTTGGCTCTTGGCGGGACCGGCCC TTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTTCACCCGCTGCTCAAGGTCCGCTCCCAGTTCCGACAG ATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGCTCCTTCTGGAACTTTGACGCCCTCTTCCAGCCCCAG CAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAGGCCCTGCAGCTCCCAATGGACTATGTCCAGCGGGTC AAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGGAAGCTGGACGAGGCCCGGAAAAACCTACTGCGAACC CACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCCTTCACTCCGGTCAAGTACTTCTCCATCGACCGCGTA TTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAGGGCGTGGTGGCGGATCATGGTCTCACCTTGGGCCAC CTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGCTTCAAGCCAGCCTACAACCCATACACAGAGCCCAGC ATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAACTCGGGGGTCTTCCGTCCAGAGATGCTGCTGCCCATG GGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCAACGATGATCAAATATGGCATCAACAATATCCGGGAG CTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGCCTGGATGCCGAGCCGAGGCCCCCTCCCACACAGGAG >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000314606_chr19_13041563_-_1542nt ATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTCCAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACA GGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGCATCAAGACTCAAACTGTCATCGAGGCTGAACTT CGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGCAGCCATGAGGCCCGTGTGTTTCGAAGCATTCCC CCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTCAGCAAGGCCATGTCCAACAAGTGGATTCGGGTG GACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGATGAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGG GGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTGTTGGCTGAAGTGACTCTGAAGACCTACTGGGTG AGCAAAGGCAGTGCCTTTAGTACCAGCATCTCCAAGCAAGAGACAGAGCTGAGCCCAGAGATGATCTCCAGTGGCTCTTGGCGGGACCGG CCCTTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTTCACCCGCTGCTCAAGGTCCGCTCCCAGTTCCGA CAGATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGCTCCTTCTGGAACTTTGACGCCCTCTTCCAGCCC CAGCAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAGGCCCTGCAGCTCCCAATGGACTATGTCCAGCGG GTCAAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGGAAGCTGGACGAGGCCCGGAAAAACCTACTGCGA ACCCACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCCTTCACTCCGGTCAAGTACTTCTCCATCGACCGC GTATTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAGGGCGTGGTGGCGGATCATGGTCTCACCTTGGGC CACCTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGCTTCAAGCCAGCCTACAACCCATACACAGAGCCC AGCATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAACTCGGGGGTCTTCCGTCCAGAGATGCTGCTGCCC ATGGGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCAACGATGATCAAATATGGCATCAACAATATCCGG GAGCTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGCCTGGATGCCGAGCCGAGGCCCCCTCCCACACAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000588025_chr19_13041563_-_1934nt CGCTTCCGCCGGTGGGACGGAACTGGTGCCCTCCGTGGACAATTGTGTTGAAGCAGAAATTGTTCCGGATCTCGGGTCGGACACGGAAGT CTTCCTGCAGTGTTTCTGGATGCGGGGACAGGGATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTC CAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACAGGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGC ATCAAGACTCAAACTGTCATCGAGGCTGAACTTCGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGC AGCCATGAGGCCCGTGTGTTTCGAAGCATTCCCCCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTC AGCAAGGCCATGTCCAACAAGTGGATTCGGGTGGACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGAT GAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGGGGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTG TTGGCTGAAGTGACTCTGAAGACCTACTGGGTGAGCAAAGGCAGTGCCTTTAGTACCAGCATCTCCAAGCAAGAGACAGAGCTGAGCCCA GAGATGATCTCCAGTGGCTCTTGGCGGGACCGGCCCTTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTT CACCCGCTGCTCAAGGTCCGCTCCCAGTTCCGACAGATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGC TCCTTCTGGAACTTTGACGCCCTCTTCCAGCCCCAGCAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAG GCCCTGCAGCTCCCAATGGACTATGTCCAGCGGGTCAAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGG AAGCTGGACGAGGCCCGGAAAAACCTACTGCGAACCCACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCC TTCACTCCGGTCAAGTACTTCTCCATCGACCGCGTATTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAG GGCGTGGTGGCGGATCATGGTCTCACCTTGGGCCACCTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGC TTCAAGCCAGCCTACAACCCATACACAGAGCCCAGCATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAAC TCGGGGGTCTTCCGTCCAGAGATGCTGCTGCCCATGGGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCA ACGATGATCAAATATGGCATCAACAATATCCGGGAGCTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGC CTGGATGCCGAGCCGAGGCCCCCTCCCACACAGGAGGCTGCGTGACATGGGCCACTCTAGGACAGGTCATCCTCCCCGAGTCCCTGCTGC TGCGCTCCTTTGCATCCCTGGCCAGTGACCTTGTATTTATGAGGCCTCTGTGAGGCCAGCCCCCACCTTCCTCTTTCCCACCTGTCCCAG GACCAGAATCCCAGGGACAGAGGACTGGGTAGCAGGTTCCTTCTGTTGTCCTGTGTGGTGTGTCTACTGTGAGGGTGGGCCCTGAGGAGA >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000423140_chr19_13041563_-_1840nt CGCTTCCGCCGGTGGGACGGAACTGGTGCCCTCCGTGGACAATTGTGTTGAAGCAGAAATTGTTCCGGATCTCGGGTCGGACACGGAAGT CTTCCTGCAGTGTTTCTGGATGCGGGGACAGGGATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTC CAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACAGGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGC ATCAAGACTCAAACTGTCATCGAGGCTGAACTTCGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGC AGCCATGAGGCCCGTGTGTTTCGAAGCATTCCCCCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTC AGCAAGGCCATGTCCAACAAGTGGATTCGGGTGGACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGAT GAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGGGGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTG TTGGCTGAAGTTGGCTCTTGGCGGGACCGGCCCTTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTTCAC CCGCTGCTCAAGGTCCGCTCCCAGTTCCGACAGATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGCTCC TTCTGGAACTTTGACGCCCTCTTCCAGCCCCAGCAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAGGCC CTGCAGCTCCCAATGGACTATGTCCAGCGGGTCAAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGGAAG CTGGACGAGGCCCGGAAAAACCTACTGCGAACCCACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCCTTC ACTCCGGTCAAGTACTTCTCCATCGACCGCGTATTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAGGGC GTGGTGGCGGATCATGGTCTCACCTTGGGCCACCTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGCTTC AAGCCAGCCTACAACCCATACACAGAGCCCAGCATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAACTCG GGGGTCTTCCGTCCAGAGATGCTGCTGCCCATGGGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCAACG ATGATCAAATATGGCATCAACAATATCCGGGAGCTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGCCTG GATGCCGAGCCGAGGCCCCCTCCCACACAGGAGGCTGCGTGACATGGGCCACTCTAGGACAGGTCATCCTCCCCGAGTCCCTGCTGCTGC GCTCCTTTGCATCCCTGGCCAGTGACCTTGTATTTATGAGGCCTCTGTGAGGCCAGCCCCCACCTTCCTCTTTCCCACCTGTCCCAGGAC CAGAATCCCAGGGACAGAGGACTGGGTAGCAGGTTCCTTCTGTTGTCCTGTGTGGTGTGTCTACTGTGAGGGTGGGCCCTGAGGAGACCT >In-frame_ZNF490_ENST00000311437_chr19_12719972_-_FARSA_ENST00000314606_chr19_13041563_-_1933nt CGCTTCCGCCGGTGGGACGGAACTGGTGCCCTCCGTGGACAATTGTGTTGAAGCAGAAATTGTTCCGGATCTCGGGTCGGACACGGAAGT CTTCCTGCAGTGTTTCTGGATGCGGGGACAGGGATGCGCAGGAATTCCAGTCTCAGTTTCCAGATGGAGCGACCCCTCGAGGAGCAAGTC CAGAGCAAGTGGTCGTCTAGTCAAGGCCGCACAGGAACAGGAGGGTCTGATGTCCTCCAGATGCAGAACAGTGAACACCATGGACAAAGC ATCAAGACTCAAACTGTCATCGAGGCTGAACTTCGGTCCACCAAGCACTGGGAGCTTACTGCGGAGGGCGAGGAGATTGCCCGGGAGGGC AGCCATGAGGCCCGTGTGTTTCGAAGCATTCCCCCAGAGGGCCTGGCCCAGAGCGAGCTTATGCGACTGCCCAGTGGCAAAGTGGGCTTC AGCAAGGCCATGTCCAACAAGTGGATTCGGGTGGACAAGAGTGCGGCTGACGGGCCCCGGGTGTTCCGAGTGGTGGACAGCATGGAGGAT GAGGTGCAGCGGCGGCTCCAGCTGGTCCGGGGGGGACAGGCTGAGAAGCTGGGGGAGAAGGAGAGGAGCGAGCTGAGGAAGAGGAAGCTG TTGGCTGAAGTGACTCTGAAGACCTACTGGGTGAGCAAAGGCAGTGCCTTTAGTACCAGCATCTCCAAGCAAGAGACAGAGCTGAGCCCA GAGATGATCTCCAGTGGCTCTTGGCGGGACCGGCCCTTCAAGCCCTACAACTTCTTGGCCCACGGTGTCCTCCCCGACAGCGGCCACCTT CACCCGCTGCTCAAGGTCCGCTCCCAGTTCCGACAGATCTTCCTGGAGATGGGGTTCACCGAGATGCCGACTGATAACTTCATTGAGAGC TCCTTCTGGAACTTTGACGCCCTCTTCCAGCCCCAGCAGCACCCAGCCCGTGACCAGCACGACACCTTCTTCCTTCGAGATCCAGCGGAG GCCCTGCAGCTCCCAATGGACTATGTCCAGCGGGTCAAGCGGACCCACTCTCAGGGCGGCTACGGCTCACAGGGGTACAAGTATAACTGG AAGCTGGACGAGGCCCGGAAAAACCTACTGCGAACCCACACCACATCAGCCAGCGCCCGTGCGCTCTACCGCCTTGCCCAGAAGAAGCCC TTCACTCCGGTCAAGTACTTCTCCATCGACCGCGTATTCCGGAATGAGACCCTGGACGCCACGCACCTGGCTGAGTTCCACCAGATCGAG GGCGTGGTGGCGGATCATGGTCTCACCTTGGGCCACCTCATGGGCGTTCTGCGGGAGTTCTTCACCAAGCTGGGTATCACGCAACTCCGC TTCAAGCCAGCCTACAACCCATACACAGAGCCCAGCATGGAGGTGTTCAGCTACCACCAAGGCCTGAAGAAGTGGGTGGAGGTCGGAAAC TCGGGGGTCTTCCGTCCAGAGATGCTGCTGCCCATGGGGCTTCCCGAGAACGTGTCGGTCATTGCCTGGGGCCTCTCCCTGGAGCGCCCA ACGATGATCAAATATGGCATCAACAATATCCGGGAGCTGGTGGGCCACAAGGTGAACCTGCAGATGGTGTATGACAGTCCCCTGTGCCGC CTGGATGCCGAGCCGAGGCCCCCTCCCACACAGGAGGCTGCGTGACATGGGCCACTCTAGGACAGGTCATCCTCCCCGAGTCCCTGCTGC TGCGCTCCTTTGCATCCCTGGCCAGTGACCTTGTATTTATGAGGCCTCTGTGAGGCCAGCCCCCACCTTCCTCTTTCCCACCTGTCCCAG GACCAGAATCCCAGGGACAGAGGACTGGGTAGCAGGTTCCTTCTGTTGTCCTGTGTGGTGTGTCTACTGTGAGGGTGGGCCCTGAGGAGA |
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FusionGenePPI for ZNF490_FARSA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZNF490 | LZTR1, HOXB13, RNPS1, ZBTB32, RBMX, TBX21, DTNBP1, MDFI, MTUS2, CCNDBP1, ZC4H2, CCDC136, CEP70, TSGA10, NDEL1, LZTS2, TRIM41, KRT40, KRTAP10-7, KRTAP10-3, TRIM39, RPL36AL, EEF1A2, TOMM34, PRDM15, NEMF, RPL26L1, LMNA | FARSA | USP11, USP32, UBC, EIF2AK2, UNC93B1, CUL3, CUL1, FBXO6, A2M, ECSIT, APOE, RNF32, FARSB, EEF2, CFTR, PAN2, TDGF1, GORAB, PUS1, RPLP0, WWOX, ASB4, ABI3, EGFR, ESR1, CCT6B, NTRK1, CDC42, IRF2BP1, KIAA0368, OGT, PRPS1, PSMG2, TARS, OFD1, XRCC3, MCM2, NF2, RC3H1, WWP2, ZNF746, CYLD, DLD, SDHA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF490_FARSA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF490_FARSA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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