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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 43302

FusionGeneSummary for ZNF423_CCAR1

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF423_CCAR1
Fusion gene ID: 43302
HgeneTgene
Gene symbol

ZNF423

CCAR1

Gene ID

23090

55749

Gene namezinc finger protein 423cell division cycle and apoptosis regulator 1
SynonymsEbfaz|JBTS19|NPHP14|OAZ|Roaz|ZFP423|Zfp104|hOAZ-
Cytomap

16q12.1

10q21.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 423OLF-1/EBF associated zinc fingerSmad- and Olf-interacting zinc finger proteinearly B-cell factor associated zinc finger proteinolf1/EBF-associated zinc finger proteincell division cycle and apoptosis regulator protein 1cell cycle and apoptosis regulatory protein 1death inducer with SAP domain
Modification date2018052320180522
UniProtAcc

Q2M1K9

Q8IX12

Ensembl transtripts involved in fusion geneENST00000561648, ENST00000563137, 
ENST00000562871, ENST00000262383, 
ENST00000535559, ENST00000567169, 
ENST00000562520, 
ENST00000535016, 
ENST00000265872, ENST00000543719, 
ENST00000483264, 
Fusion gene scores* DoF score5 X 4 X 3=603 X 3 X 2=18
# samples 44
** MAII scorelog2(4/60*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ZNF423 [Title/Abstract] AND CCAR1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZNF423

GO:0045892

negative regulation of transcription, DNA-templated

10660046

HgeneZNF423

GO:0045893

positive regulation of transcription, DNA-templated

10660046


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVUCSTCGA-N8-A4PQ-01AZNF423chr16

49764682

-CCAR1chr10

70545893

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000561648ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
In-frameENST00000561648ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
In-frameENST00000561648ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
5CDS-intronENST00000561648ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000563137ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000563137ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000563137ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
5CDS-intronENST00000563137ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562871ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562871ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562871ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
5CDS-intronENST00000562871ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000262383ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000262383ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000262383ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
5CDS-intronENST00000262383ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000535559ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000535559ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000535559ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-intronENST00000535559ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000567169ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000567169ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-3CDSENST00000567169ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
intron-intronENST00000567169ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562520ENST00000535016ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562520ENST00000265872ZNF423chr16

49764682

-CCAR1chr10

70545893

+
Frame-shitENST00000562520ENST00000543719ZNF423chr16

49764682

-CCAR1chr10

70545893

+
5CDS-intronENST00000562520ENST00000483264ZNF423chr16

49764682

-CCAR1chr10

70545893

+

Top

FusionProtFeatures for ZNF423_CCAR1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ZNF423

Q2M1K9

CCAR1

Q8IX12

Transcription factor that can both act as an activatoror a repressor depending on the context. Plays a central role inBMP signaling and olfactory neurogenesis. Associates with SMADs inresponse to BMP2 leading to activate transcription of BMP targetgenes. Acts as a transcriptional repressor via its interactionwith EBF1, a transcription factor involved in terminal olfactoryreceptor neurons differentiation; this interaction preventing EBF1to bind DNA and activate olfactory-specific genes. Involved inolfactory neurogenesis by participating in a developmental switchthat regulates the transition from differentiation to maturationin olfactory receptor neurons. Controls proliferation anddifferentiation of neural precursors in cerebellar vermisformation. {ECO:0000269|PubMed:10660046}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-4967_93921285Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-3867_93921285Zinc fingerC2H2-type 1%3B degenerate
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+18251033_11148831151Coiled coilOntology_term=ECO:0000255
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+17241033_11148681136Coiled coilOntology_term=ECO:0000255
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+17241033_11148681136Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491020_1042921285Zinc fingerC2H2-type 24
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491064_1082921285Zinc fingerC2H2-type 25%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491120_1143921285Zinc fingerC2H2-type 26
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491168_1190921285Zinc fingerC2H2-type 27
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491198_1220921285Zinc fingerC2H2-type 28
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491229_1252921285Zinc fingerC2H2-type 29
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-491259_1282921285Zinc fingerC2H2-type 30
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49138_160921285Zinc fingerC2H2-type 2
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49166_188921285Zinc fingerC2H2-type 3
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49194_216921285Zinc fingerC2H2-type 4
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49222_244921285Zinc fingerC2H2-type 5
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49263_286921285Zinc fingerC2H2-type 6
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49295_318921285Zinc fingerC2H2-type 7
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49323_345921285Zinc fingerC2H2-type 8
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49409_433921285Zinc fingerC2H2-type 9%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49441_464921285Zinc fingerC2H2-type 10
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49480_503921285Zinc fingerC2H2-type 11
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49517_540921285Zinc fingerC2H2-type 12
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49563_588921285Zinc fingerC2H2-type 13%3B atypical
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49632_654921285Zinc fingerC2H2-type 14
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49662_684921285Zinc fingerC2H2-type 15
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49692_715921285Zinc fingerC2H2-type 16
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49720_743921285Zinc fingerC2H2-type 17
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49750_773921285Zinc fingerC2H2-type 18
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49781_803921285Zinc fingerC2H2-type 19
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49807_830921285Zinc fingerC2H2-type 20
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49886_908921285Zinc fingerC2H2-type 21%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49930_952921285Zinc fingerC2H2-type 22
HgeneZNF423chr16:49764682chr10:70545893ENST00000262383-49959_981921285Zinc fingerC2H2-type 23
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381020_1042921285Zinc fingerC2H2-type 24
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381064_1082921285Zinc fingerC2H2-type 25%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381120_1143921285Zinc fingerC2H2-type 26
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381168_1190921285Zinc fingerC2H2-type 27
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381198_1220921285Zinc fingerC2H2-type 28
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381229_1252921285Zinc fingerC2H2-type 29
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-381259_1282921285Zinc fingerC2H2-type 30
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38138_160921285Zinc fingerC2H2-type 2
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38166_188921285Zinc fingerC2H2-type 3
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38194_216921285Zinc fingerC2H2-type 4
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38222_244921285Zinc fingerC2H2-type 5
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38263_286921285Zinc fingerC2H2-type 6
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38295_318921285Zinc fingerC2H2-type 7
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38323_345921285Zinc fingerC2H2-type 8
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38409_433921285Zinc fingerC2H2-type 9%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38441_464921285Zinc fingerC2H2-type 10
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38480_503921285Zinc fingerC2H2-type 11
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38517_540921285Zinc fingerC2H2-type 12
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38563_588921285Zinc fingerC2H2-type 13%3B atypical
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38632_654921285Zinc fingerC2H2-type 14
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38662_684921285Zinc fingerC2H2-type 15
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38692_715921285Zinc fingerC2H2-type 16
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38720_743921285Zinc fingerC2H2-type 17
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38750_773921285Zinc fingerC2H2-type 18
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38781_803921285Zinc fingerC2H2-type 19
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38807_830921285Zinc fingerC2H2-type 20
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38886_908921285Zinc fingerC2H2-type 21%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38930_952921285Zinc fingerC2H2-type 22
HgeneZNF423chr16:49764682chr10:70545893ENST00000561648-38959_981921285Zinc fingerC2H2-type 23
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381020_1042321225Zinc fingerC2H2-type 24
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381064_1082321225Zinc fingerC2H2-type 25%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381120_1143321225Zinc fingerC2H2-type 26
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381168_1190321225Zinc fingerC2H2-type 27
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381198_1220321225Zinc fingerC2H2-type 28
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381229_1252321225Zinc fingerC2H2-type 29
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-381259_1282321225Zinc fingerC2H2-type 30
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38138_160321225Zinc fingerC2H2-type 2
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38166_188321225Zinc fingerC2H2-type 3
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38194_216321225Zinc fingerC2H2-type 4
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38222_244321225Zinc fingerC2H2-type 5
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38263_286321225Zinc fingerC2H2-type 6
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38295_318321225Zinc fingerC2H2-type 7
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38323_345321225Zinc fingerC2H2-type 8
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38409_433321225Zinc fingerC2H2-type 9%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38441_464321225Zinc fingerC2H2-type 10
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38480_503321225Zinc fingerC2H2-type 11
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38517_540321225Zinc fingerC2H2-type 12
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38563_588321225Zinc fingerC2H2-type 13%3B atypical
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38632_654321225Zinc fingerC2H2-type 14
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38662_684321225Zinc fingerC2H2-type 15
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-3867_93321225Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38692_715321225Zinc fingerC2H2-type 16
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38720_743321225Zinc fingerC2H2-type 17
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38750_773321225Zinc fingerC2H2-type 18
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38781_803321225Zinc fingerC2H2-type 19
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38807_830321225Zinc fingerC2H2-type 20
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38886_908321225Zinc fingerC2H2-type 21%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38930_952321225Zinc fingerC2H2-type 22
HgeneZNF423chr16:49764682chr10:70545893ENST00000562520-38959_981321225Zinc fingerC2H2-type 23
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271020_1042321225Zinc fingerC2H2-type 24
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271064_1082321225Zinc fingerC2H2-type 25%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271120_1143321225Zinc fingerC2H2-type 26
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271168_1190321225Zinc fingerC2H2-type 27
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271198_1220321225Zinc fingerC2H2-type 28
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271229_1252321225Zinc fingerC2H2-type 29
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-271259_1282321225Zinc fingerC2H2-type 30
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27138_160321225Zinc fingerC2H2-type 2
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27166_188321225Zinc fingerC2H2-type 3
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27194_216321225Zinc fingerC2H2-type 4
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27222_244321225Zinc fingerC2H2-type 5
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27263_286321225Zinc fingerC2H2-type 6
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27295_318321225Zinc fingerC2H2-type 7
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27323_345321225Zinc fingerC2H2-type 8
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27409_433321225Zinc fingerC2H2-type 9%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27441_464321225Zinc fingerC2H2-type 10
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27480_503321225Zinc fingerC2H2-type 11
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27517_540321225Zinc fingerC2H2-type 12
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27563_588321225Zinc fingerC2H2-type 13%3B atypical
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27632_654321225Zinc fingerC2H2-type 14
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27662_684321225Zinc fingerC2H2-type 15
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-2767_93321225Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27692_715321225Zinc fingerC2H2-type 16
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27720_743321225Zinc fingerC2H2-type 17
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27750_773321225Zinc fingerC2H2-type 18
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27781_803321225Zinc fingerC2H2-type 19
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27807_830321225Zinc fingerC2H2-type 20
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27886_908321225Zinc fingerC2H2-type 21%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27930_952321225Zinc fingerC2H2-type 22
HgeneZNF423chr16:49764682chr10:70545893ENST00000562871-27959_981321225Zinc fingerC2H2-type 23
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381020_1042321225Zinc fingerC2H2-type 24
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381064_1082321225Zinc fingerC2H2-type 25%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381120_1143321225Zinc fingerC2H2-type 26
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381168_1190321225Zinc fingerC2H2-type 27
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381198_1220321225Zinc fingerC2H2-type 28
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381229_1252321225Zinc fingerC2H2-type 29
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-381259_1282321225Zinc fingerC2H2-type 30
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38138_160321225Zinc fingerC2H2-type 2
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38166_188321225Zinc fingerC2H2-type 3
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38194_216321225Zinc fingerC2H2-type 4
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38222_244321225Zinc fingerC2H2-type 5
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38263_286321225Zinc fingerC2H2-type 6
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38295_318321225Zinc fingerC2H2-type 7
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38323_345321225Zinc fingerC2H2-type 8
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38409_433321225Zinc fingerC2H2-type 9%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38441_464321225Zinc fingerC2H2-type 10
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38480_503321225Zinc fingerC2H2-type 11
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38517_540321225Zinc fingerC2H2-type 12
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38563_588321225Zinc fingerC2H2-type 13%3B atypical
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38632_654321225Zinc fingerC2H2-type 14
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38662_684321225Zinc fingerC2H2-type 15
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-3867_93321225Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38692_715321225Zinc fingerC2H2-type 16
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38720_743321225Zinc fingerC2H2-type 17
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38750_773321225Zinc fingerC2H2-type 18
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38781_803321225Zinc fingerC2H2-type 19
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38807_830321225Zinc fingerC2H2-type 20
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38886_908321225Zinc fingerC2H2-type 21%3B degenerate
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38930_952321225Zinc fingerC2H2-type 22
HgeneZNF423chr16:49764682chr10:70545893ENST00000563137-38959_981321225Zinc fingerC2H2-type 23
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825594_6188831151Coiled coilOntology_term=ECO:0000255
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724594_6188681136Coiled coilOntology_term=ECO:0000255
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724594_6188681136Coiled coilOntology_term=ECO:0000255
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825293_3618831151Compositional biasNote=Arg-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825673_8898831151Compositional biasNote=Glu-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+182573_798831151Compositional biasNote=Poly-Ala
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724293_3618681136Compositional biasNote=Arg-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724673_8898681136Compositional biasNote=Glu-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+172473_798681136Compositional biasNote=Poly-Ala
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724293_3618681136Compositional biasNote=Arg-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724673_8898681136Compositional biasNote=Glu-rich
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+172473_798681136Compositional biasNote=Poly-Ala
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825636_6708831151DomainSAP
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724636_6708681136DomainSAP
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724636_6708681136DomainSAP


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FusionGeneSequence for ZNF423_CCAR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000535016_chr10_70545893_+_360aa
MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRC
PGDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVTFDQSHCGYLLEKDLEEILTTLGLHLSRAQVKKLLNKVVLR
ESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEK
TDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV_

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000265872_chr10_70545893_+_360aa
MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRC
PGDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVTFDQSHCGYLLEKDLEEILTTLGLHLSRAQVKKLLNKVVLR
ESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEK
TDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV_

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000543719_chr10_70545893_+_360aa
MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRC
PGDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVTFDQSHCGYLLEKDLEEILTTLGLHLSRAQVKKLLNKVVLR
ESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEK
TDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV_


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000535016_chr10_70545893_+_1080nt
ATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCAGACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGA
GAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTGGAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGAC
ATGGAGGATGAATCAATTTACACCTGCGATCACTGTCAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGT
CCTGGAGATAGGGATGAGGAAGAAATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAG
GAAAAAGAAAAGACTCAAATGATCACAATTAACAGAGATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTT
GAAAAGGATTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGT
GAATCTTGCTTTTACCGGAAATTAACAGACACCTCAAAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGA
AACAGATTATTACTTCCAACACCAACAGTAAAGCAGGAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATG
GTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAGAGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAA
ACAGATGAAGATGAAAAAACCATATTAAATTTGGAGAATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGT
CAGTTACAAGAAAACTTAAAGATTTCGGAAAACATGAATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTA
ATGGATGAAATCCACACTGTTCTCAAGAAGGATAATGTAAAGAATGAAGACAAAGATCAAAAATCCAAGGAGAATGGTGCCAGTGTATGA

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000265872_chr10_70545893_+_1080nt
ATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCAGACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGA
GAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTGGAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGAC
ATGGAGGATGAATCAATTTACACCTGCGATCACTGTCAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGT
CCTGGAGATAGGGATGAGGAAGAAATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAG
GAAAAAGAAAAGACTCAAATGATCACAATTAACAGAGATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTT
GAAAAGGATTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGT
GAATCTTGCTTTTACCGGAAATTAACAGACACCTCAAAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGA
AACAGATTATTACTTCCAACACCAACAGTAAAGCAGGAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATG
GTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAGAGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAA
ACAGATGAAGATGAAAAAACCATATTAAATTTGGAGAATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGT
CAGTTACAAGAAAACTTAAAGATTTCGGAAAACATGAATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTA
ATGGATGAAATCCACACTGTTCTCAAGAAGGATAATGTAAAGAATGAAGACAAAGATCAAAAATCCAAGGAGAATGGTGCCAGTGTATGA

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000543719_chr10_70545893_+_1080nt
ATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCAGACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGA
GAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTGGAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGAC
ATGGAGGATGAATCAATTTACACCTGCGATCACTGTCAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGT
CCTGGAGATAGGGATGAGGAAGAAATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAG
GAAAAAGAAAAGACTCAAATGATCACAATTAACAGAGATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTT
GAAAAGGATTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGT
GAATCTTGCTTTTACCGGAAATTAACAGACACCTCAAAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGA
AACAGATTATTACTTCCAACACCAACAGTAAAGCAGGAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATG
GTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAGAGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAA
ACAGATGAAGATGAAAAAACCATATTAAATTTGGAGAATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGT
CAGTTACAAGAAAACTTAAAGATTTCGGAAAACATGAATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTA
ATGGATGAAATCCACACTGTTCTCAAGAAGGATAATGTAAAGAATGAAGACAAAGATCAAAAATCCAAGGAGAATGGTGCCAGTGTATGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000535016_chr10_70545893_+_1420nt
GGAAAACTTCCTGGAGAAGGATGGATTTTACCCTGTAAAAGAAGAAAGACATGGATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCA
GACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGAGAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTG
GAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGACATGGAGGATGAATCAATTTACACCTGCGATCACTGT
CAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGTCCTGGAGATAGGGATGAGGAAGAAATGACCAAACGA
GATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAGGAAAAAGAAAAGACTCAAATGATCACAATTAACAGA
GATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTTGAAAAGGATTTGGAAGAAATACTTTATACTCTTGGA
CTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGTGAATCTTGCTTTTACCGGAAATTAACAGACACCTCA
AAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGAAACAGATTATTACTTCCAACACCAACAGTAAAGCAG
GAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATGGTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAG
AGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAAACAGATGAAGATGAAAAAACCATATTAAATTTGGAG
AATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGTCAGTTACAAGAAAACTTAAAGATTTCGGAAAACATG
AATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTAATGGATGAAATCCACACTGTTCTCAAGAAGGATAAT
GTAAAGAATGAAGACAAAGATCAAAAATCCAAGGAGAATGGTGCCAGTGTATGATAAAATCCATGTAGTGATGAGGAATGGTGTTAAATA
ATGTAATATATAAAAATCATGATATAAGAATGTTTGAAGGTGATGCATGTTTGATTTTAGTAGTATAAATGTATTTTAGTTCAAATGATG
TATAAAGTTTTATGAATGTGAGTTTCTGCTTTTGAAAATTGCTTGTAATTCCTAGCCTTCAAATTATTAAACACTCCTTGAGTGAAATAA

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000265872_chr10_70545893_+_2245nt
GGAAAACTTCCTGGAGAAGGATGGATTTTACCCTGTAAAAGAAGAAAGACATGGATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCA
GACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGAGAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTG
GAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGACATGGAGGATGAATCAATTTACACCTGCGATCACTGT
CAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGTCCTGGAGATAGGGATGAGGAAGAAATGACCAAACGA
GATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAGGAAAAAGAAAAGACTCAAATGATCACAATTAACAGA
GATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTTGAAAAGGATTTGGAAGAAATACTTTATACTCTTGGA
CTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGTGAATCTTGCTTTTACCGGAAATTAACAGACACCTCA
AAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGAAACAGATTATTACTTCCAACACCAACAGTAAAGCAG
GAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATGGTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAG
AGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAAACAGATGAAGATGAAAAAACCATATTAAATTTGGAG
AATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGTCAGTTACAAGAAAACTTAAAGATTTCGGAAAACATG
AATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTAATGGATGAAATCCACACTGTTCTCAAGAAGGATAAT
GTAAAGAATGAAGACAAAGATCAAAAATCCAAGGAGAATGGTGCCAGTGTATGATAAAATCCATGTAGTGATGAGGAATGGTGTTAAATA
ATGTAATATATAAAAATCATGATATAAGAATGTTTGAAGGTGATGCATGTTTGATTTTAGTAGTATAAATGTATTTTAGTTCAAATGATG
TATAAAGTTTTATGAATGTGAGTTTCTGCTTTTGAAAATTGCTTGTAATTCCTAGCCTTCAAATTATTAAACACTCCTTGAGTGAAATAA
TTTTGCATTGCAAAGTGTTTTAGGATGAACTTTGTTATAGTTTTAACTCCAATAAAGTTCATCAGTTTAATTGACTGTAGTATTTAATTA
CCAAATTTCTTTTATTAAAATGCCTAGAAATTTTTAATTTATAGAATTATTAGGTTTTAAAATTTTTAGTTCATCTGTTAAAATTTCAGT
CAAAATCATAAAATAGCATGATGCTTAATTTTTGCAAGTTTTTTGAAACTTTTTGTTTTTTTTACTCATCACCAAAAAATCCCCTCTTGA
TCAGTCTCTAAAAGCATTCATTAAAAATTCAGTTCAGGCCGGGCACGGTGGCTCACACCTGTAATCCCAACACTTTGGGAGGCCGAGGCA
GGTGGATCACCTGAGGTTAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCGGTCTCTACTAAAAATATAAAAATTAGCTGGGCA
TGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTCACTCAGG
ATCATGCAGCTACACTCCAGCCTGGGCGACAAGAGTGAAACTCCATCTCAAAAAGAAAAAAAAAAAAAATCAGTTTATTTGAAAGACAGT
ATATCAGAAAGAAAGAAGCAATAGAGAACTAGTATTGTTCTTTATGGGTTAGACTTTACATAATATTAGTTGTCCTGATGTCAATGTTAC
TGCTTTCAATTAATTTTTCTACTTTCCCAGAATAGCATCTATATTCCTTTTAATTTTGAGGGTTTAAAAAAAAATGCAGTGTATGTCAAA

>In-frame_ZNF423_ENST00000561648_chr16_49764682_-_CCAR1_ENST00000543719_chr10_70545893_+_1134nt
GGAAAACTTCCTGGAGAAGGATGGATTTTACCCTGTAAAAGAAGAAAGACATGGATGCATAAGAAGAGGGTTGAAGAGGGGGAGGCCTCA
GACTTCTCGCTGGCCTGGGATTCCTCCGTGACAGCAGCAGGAGGCCTAGAAGGAGAGCCAGAGTGCGATCAGAAAACCAGCCGTGCGCTG
GAAGACAGGAACAGCGTGACAAGTCAAGAGGAGAGAAATGAGGATGATGAAGACATGGAGGATGAATCAATTTACACCTGCGATCACTGT
CAGCAGGACTTCGAGTCTCTGGCAGACCTGACGGACCACCGGGCCCACCGCTGTCCTGGAGATAGGGATGAGGAAGAAATGACCAAACGA
GATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAGGAAAAAGAAAAGACTCAAATGATCACAATTAACAGA
GATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGTCATTGTGGTTACCTTCTTGAAAAGGATTTGGAAGAAATACTTTATACTCTTGGA
CTACATCTTTCTCGGGCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGTGAATCTTGCTTTTACCGGAAATTAACAGACACCTCA
AAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGAAACAGATTATTACTTCCAACACCAACAGTAAAGCAG
GAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTACAATGGTGCAATGGTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAG
AGCGAAAAAGTAAGAGCTGAGGTAGAACAGAAGCTGCAGTTACTAGAAGAAAAAACAGATGAAGATGAAAAAACCATATTAAATTTGGAG
AATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGTCAGTTACAAGAAAACTTAAAGATTTCGGAAAACATG
AATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCTACGGTAATGGATGAAATCCACACTGTTCTCAAGAAGGATAAT


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FusionGenePPI for ZNF423_CCAR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ZNF423PARP1, SMAD4, SMAD1, EBF1, EBF2, EBF3, USP7, CEP290, LYN, BRCA1, MTA1, ZNF219, RBBP7, MBD3L1, ZG16BCCAR1YWHAQ, MDM2, TP53, FYCO1, SF3A2, SIRT7, BARD1, SMURF1, U2AF2, CHERP, RBM10, HNRNPK, RNF113A, UBL4A, GOLGA2, PIH1D3, GRPEL1, FHL3, QPRT, WRAP73, ACTR1A, ACTR1B, CAND1, RCN1, SF3B3, DCTN1, DCTN2, DYNC1I2, PCNA, PRIM1, PSMD4, SAFB2, TNKS1BP1, TPM2, NTRK1, MED4, SSX2IP, HIST1H3E, MYO1C, XRCC3, EMC2, MMGT1, PCGF1, CCNB1, ZYX, IKBKG


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+18251_2498831151AR
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+17241_2498681136AR
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+17241_2498681136AR
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825643_11508831151GATA1
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724643_11508681136GATA1
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724643_11508681136GATA1
TgeneCCAR1chr16:49764682chr10:70545893ENST00000265872+1825203_6608831151GATA2
TgeneCCAR1chr16:49764682chr10:70545893ENST00000535016+1724203_6608681136GATA2
TgeneCCAR1chr16:49764682chr10:70545893ENST00000543719+1724203_6608681136GATA2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ZNF423_CCAR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF423_CCAR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneZNF423C0236733Amphetamine-Related Disorders1CTD_human
HgeneZNF423C3539071NEPHRONOPHTHISIS 141UNIPROT