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Fusion gene ID: 43281 |
FusionGeneSummary for ZNF410_ANKS3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF410_ANKS3 | Fusion gene ID: 43281 | Hgene | Tgene | Gene symbol | ZNF410 | ANKS3 | Gene ID | 57862 | 124401 |
| Gene name | zinc finger protein 410 | ankyrin repeat and sterile alpha motif domain containing 3 | |
| Synonyms | APA-1|APA1 | - | |
| Cytomap | 14q24.3 | 16p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 410another partner for ARF 1clones 23667 and 23775 zinc finger proteinzinc finger protein APA-1 | ankyrin repeat and SAM domain-containing protein 3 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q86VK4 | Q6ZW76 | |
| Ensembl transtripts involved in fusion gene | ENST00000540593, ENST00000324593, ENST00000412490, ENST00000442160, ENST00000555044, ENST00000334521, ENST00000556797, | ENST00000446014, ENST00000304283, ENST00000585773, ENST00000450067, ENST00000592711, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ZNF410 [Title/Abstract] AND ANKS3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-BC-A3KG-01A | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000540593 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000540593 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000540593 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000540593 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000540593 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000324593 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000324593 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-intron | ENST00000412490 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-intron | ENST00000412490 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000442160 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000442160 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000555044 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000555044 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000334521 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000334521 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000556797 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000556797 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
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FusionProtFeatures for ZNF410_ANKS3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF410 | ANKS3 |
| Transcription factor that activates transcription ofmatrix-remodeling genes such as MMP1 during fibroblast senescence.{ECO:0000269|PubMed:12370286}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF410_ANKS3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000446014_chr16_4748063_-_308aa MLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQD EAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGEARRHFPCHYSVQRDFGNAVAGLSCIXFKLFYXXEQKAR NLXIVXILFSIKXLGHARFVFKTNXYSEFSTLNNVQSPFXRKNNIQACQAELSSRVRQDQPPGAATLGLAVPPADSKGWQASLQAMSLPE >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000304283_chr16_4748063_-_308aa MLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQD EAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGEARRHFPCHYSVQRDFGNAVAGLSCIXFKLFYXXEQKAR NLXIVXILFSIKXLGHARFVFKTNXYSEFSTLNNVQSPFXRKNNIQACQAELSSRVRQDQPPGAATLGLAVPPADSKGWQASLQAMSLPE >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000585773_chr16_4748063_-_308aa MLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQD EAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGEARRHFPCHYSVQRDFGNAVAGLSCIXFKLFYXXEQKAR NLXIVXILFSIKXLGHARFVFKTNXYSEFSTLNNVQSPFXRKNNIQACQAELSSRVRQDQPPGAATLGLAVPPADSKGWQASLQAMSLPE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000446014_chr16_4748063_-_924nt ATGTTACCAGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTCCTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGT CCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTTGTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTA CAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCTGGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGAT GAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAGCATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCAT GACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAGCAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCAC TATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATAATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGA AATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAGATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCA ACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTGTCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAG CCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGGCTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAG CTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTTAGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAAC >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000304283_chr16_4748063_-_924nt ATGTTACCAGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTCCTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGT CCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTTGTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTA CAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCTGGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGAT GAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAGCATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCAT GACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAGCAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCAC TATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATAATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGA AATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAGATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCA ACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTGTCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAG CCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGGCTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAG CTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTTAGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAAC >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000585773_chr16_4748063_-_924nt ATGTTACCAGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTCCTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGT CCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTTGTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTA CAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCTGGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGAT GAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAGCATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCAT GACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAGCAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCAC TATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATAATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGA AATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAGATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCA ACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTGTCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAG CCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGGCTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAG CTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTTAGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000446014_chr16_4748063_-_1447nt ACCGCGCGCCACTGTCTTCGCCTTCTTGCACTTCGCGGGAGAAGTTGTTGGCGCGAATGGATCCTGAGCCTCGATAACAGATTCCTCAAC CGGCCCACCCGCCAGCCAGCCAGCGCCTTCATCCTGGGGCTGCGATGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTC CTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGTCCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTT GTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTACAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCT GGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGATGAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAG CATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCATGACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAG CAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCACTATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATA ATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGAAATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAG ATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCAACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTG TCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAGCCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGG CTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAGCTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTT AGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAACGGGAAGAAGTGGCGGGAGACCTAGCCTGCGGGCCGAATCTGACGTTGGGTGAT TGGTCCACCCTGAAGCTGTGTGCCAGGGAGTGAGGAGGACAGTGAGCAGGTAGCTGCCATGTGCAGCCCAGGCCCAGTGGGGGCCAGAGG ATCAGGCCCCGGGAGCAGCCGGCAGACAGAGGCAAGACGGGGGCTGCGGCCCTGGCTCGGCAGCTCGGGCCAGCACTGAGGCGGGACGAG GGCCTCACCCAGAACCTCGTGGTGAGGCCCAGAGTTCATGGGCTGCCCTGGCCCATACCAGGCAGGGCCCTGGGGGGAAAGTGTATCCAT ATACACGCACAGGTGCCAACTGAGGTGGGACCTTAGGAATGAGGACTGGGGCACCTGGAAAATGCCATTTTTTGGAAAATAAAATTTAAG >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000304283_chr16_4748063_-_1447nt ACCGCGCGCCACTGTCTTCGCCTTCTTGCACTTCGCGGGAGAAGTTGTTGGCGCGAATGGATCCTGAGCCTCGATAACAGATTCCTCAAC CGGCCCACCCGCCAGCCAGCCAGCGCCTTCATCCTGGGGCTGCGATGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTC CTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGTCCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTT GTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTACAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCT GGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGATGAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAG CATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCATGACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAG CAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCACTATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATA ATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGAAATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAG ATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCAACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTG TCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAGCCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGG CTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAGCTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTT AGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAACGGGAAGAAGTGGCGGGAGACCTAGCCTGCGGGCCGAATCTGACGTTGGGTGAT TGGTCCACCCTGAAGCTGTGTGCCAGGGAGTGAGGAGGACAGTGAGCAGGTAGCTGCCATGTGCAGCCCAGGCCCAGTGGGGGCCAGAGG ATCAGGCCCCGGGAGCAGCCGGCAGACAGAGGCAAGACGGGGGCTGCGGCCCTGGCTCGGCAGCTCGGGCCAGCACTGAGGCGGGACGAG GGCCTCACCCAGAACCTCGTGGTGAGGCCCAGAGTTCATGGGCTGCCCTGGCCCATACCAGGCAGGGCCCTGGGGGGAAAGTGTATCCAT ATACACGCACAGGTGCCAACTGAGGTGGGACCTTAGGAATGAGGACTGGGGCACCTGGAAAATGCCATTTTTTGGAAAATAAAATTTAAG >In-frame_ZNF410_ENST00000556797_chr14_74364965_+_ANKS3_ENST00000585773_chr16_4748063_-_1102nt ACCGCGCGCCACTGTCTTCGCCTTCTTGCACTTCGCGGGAGAAGTTGTTGGCGCGAATGGATCCTGAGCCTCGATAACAGATTCCTCAAC CGGCCCACCCGCCAGCCAGCCAGCGCCTTCATCCTGGGGCTGCGATGATGATACTACAAATCATTCTAACTCCTCCAAGGAGGTCCCTTC CTCAGCTGTTTTGAGAAGCCTTCGGGTGAATGTGGGTCCAGACGGAGAGGAGACGAGAGCTCAGACTGTACAGAAATCCCCGGAGTTTTT GTCCACTTCAGAGTCTTCTAGCTTGTTGCAAGATCTACAGCCAAGTGATAGCACTTCTTTTATTCTTCTTAACCTAACAAGAGCAGGTCT GGGCTCTTCAGCTGAGCACTTAGTGTTTGTACAGGATGAGGCAGAAGATTCAGGGAATGATTTCCTCTCCAGTGAGAGCACAGACAGTAG CATTCCATGGTTCCTCCGGGTTCAGGAGTTGGCCCATGACAGTTTGATTGCTGCTACTCGTGCACAACTGGCAAAGAATGCAAAAACCAG CAGCAATGGTGAGGCCCGTCGGCATTTTCCTTGCCACTATTCTGTGCAAAGAGATTTTGGTAATGCAGTGGCTGGTTTGAGTTGTATATA ATTTAAATTATTCTATTGATGAGAGCAGAAGGCTAGAAATCTGTAAATTGTTTAAATTTTATTTTCTATAAAATAACTTGGTCATGCCAG ATTTGTGTTCAAAACCAACTAGTATTCTGAATTCTCAACTTTAAATAATGTACAGAGCCCCTTTTAAAGAAAAAATAATATACAAGCCTG TCAAGCTGAGCTGTCATCTCGAGTGAGGCAGGACCAGCCCCCTGGTGCAGCCACTCTGGGCCTAGCCGTCCCCCCAGCTGACTCCAAGGG CTGGCAAGCGTCCCTGCAGGCCATGAGCCTCCCCGAGCTCTCGGGAGCCCTGGAGGACCGTGTCCGTGAGATGGGGCAAGCACTGTGCTT AGTGACCCAGAGCCTGGAGAAGCTGCAGGTGCTGAACGGGAAGAAGTGGCGGGAGACCTAGCCTGCGGGCCGAATCTGACGTTGGGTGAT |
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FusionGenePPI for ZNF410_ANKS3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZNF410 | POLR2M, BLZF1, APP, GOLGA2, TRAF2, MTUS2, SERTAD1, CEP70, TSGA10, ZNF397, RAB3IP, FSD2, FAM9B | ANKS3 | GFI1B, NXF1, XPO1, ZNF669, ZNF214, ZNF556, ANKS6, NEK7, NEK8, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF410_ANKS3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF410_ANKS3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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