![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 43264 |
FusionGeneSummary for ZNF395_SLC25A44 |
![]() |
Fusion gene information | Fusion gene name: ZNF395_SLC25A44 | Fusion gene ID: 43264 | Hgene | Tgene | Gene symbol | ZNF395 | SLC25A44 | Gene ID | 55893 | 9673 |
Gene name | zinc finger protein 395 | solute carrier family 25 member 44 | |
Synonyms | HDBP-2|HDBP2|HDRF-2|PBF|PRF-1|PRF1|Si-1-8-14 | - | |
Cytomap | 8p21.1 | 1q22 | |
Type of gene | protein-coding | protein-coding | |
Description | zinc finger protein 395HD gene regulatory region-binding protein 2HD-regulating factor 2Huntington's disease gene regulatory region-binding protein 2huntington disease gene regulatory region-binding protein 2papillomavirus regulatory factor 1papillo | solute carrier family 25 member 44 | |
Modification date | 20180519 | 20180522 | |
UniProtAcc | Q9H8N7 | Q96H78 | |
Ensembl transtripts involved in fusion gene | ENST00000344423, ENST00000523202, ENST00000523095, ENST00000519730, | ENST00000359511, ENST00000423538, ENST00000469537, | |
Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
# samples | 3 | 3 | |
** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: ZNF395 [Title/Abstract] AND SLC25A44 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | RV | PRAD | TCGA-HC-7744-01A | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000344423 | ENST00000359511 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3CDS | ENST00000344423 | ENST00000423538 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3UTR | ENST00000344423 | ENST00000469537 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3CDS | ENST00000523202 | ENST00000359511 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3CDS | ENST00000523202 | ENST00000423538 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3UTR | ENST00000523202 | ENST00000469537 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
5UTR-3CDS | ENST00000523095 | ENST00000359511 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
5UTR-3CDS | ENST00000523095 | ENST00000423538 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
5UTR-3UTR | ENST00000523095 | ENST00000469537 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3CDS | ENST00000519730 | ENST00000359511 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3CDS | ENST00000519730 | ENST00000423538 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
intron-3UTR | ENST00000519730 | ENST00000469537 | ZNF395 | chr8 | 28243521 | - | SLC25A44 | chr1 | 156177677 | + |
Top |
FusionProtFeatures for ZNF395_SLC25A44 |
![]() |
Hgene | Tgene |
ZNF395 | SLC25A44 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for ZNF395_SLC25A44 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for ZNF395_SLC25A44 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
ZNF395 | SAP30, HDAC1, ELAVL1, WASL, FBXW11, BTRC | SLC25A44 | ELAVL1, JUP, NME2P1, IMPDH2, LASP1, IMPDH1 |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for ZNF395_SLC25A44 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF395_SLC25A44 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |