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Fusion gene ID: 43203 |
FusionGeneSummary for ZNF321P_ERGIC3 |
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Fusion gene information | Fusion gene name: ZNF321P_ERGIC3 | Fusion gene ID: 43203 | Hgene | Tgene | Gene symbol | ZNF321P | ERGIC3 | Gene ID | 399669 | 51614 |
Gene name | zinc finger protein 321, pseudogene | ERGIC and golgi 3 | |
Synonyms | ZNF321 | C20orf47|C2orf47|CGI-54|Erv46|NY-BR-84|PRO0989|SDBCAG84|dJ477O4.2 | |
Cytomap | 19q13.41 | 20q11.22 | |
Type of gene | pseudo | protein-coding | |
Description | - | endoplasmic reticulum-Golgi intermediate compartment protein 3endoplasmic reticulum-localized protein ERp43serologically defined breast cancer antigen 84serologically defined breast cancer antigen NY-BR-84 | |
Modification date | 20180329 | 20180523 | |
UniProtAcc | Q8N8H1 | Q9Y282 | |
Ensembl transtripts involved in fusion gene | ENST00000391777, | ENST00000348547, ENST00000357394, ENST00000279052, ENST00000447986, ENST00000482338, | |
Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 6 X 6 X 3=108 |
# samples | 2 | 8 | |
** MAII score | log2(2/4*10)=2.32192809488736 | log2(8/108*10)=-0.432959407276106 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: ZNF321P [Title/Abstract] AND ERGIC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | LD | BRCA | TCGA-AO-A03L-01A | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000391777 | ENST00000348547 | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
intron-3CDS | ENST00000391777 | ENST00000357394 | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
intron-3CDS | ENST00000391777 | ENST00000279052 | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
intron-3CDS | ENST00000391777 | ENST00000447986 | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
intron-intron | ENST00000391777 | ENST00000482338 | ZNF321P | chr19 | 53445794 | - | ERGIC3 | chr20 | 34130072 | + |
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FusionProtFeatures for ZNF321P_ERGIC3 |
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Hgene | Tgene |
ZNF321P | ERGIC3 |
Possible role in transport between endoplasmic reticulumand Golgi. {ECO:0000250}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF321P_ERGIC3 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ZNF321P_ERGIC3 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
ZNF321P | ERGIC3 | ERGIC1, CPSF7, COX16, PXMP2, ATP1A3, TMEM87A, SLC30A9, DNAJC11, FLVCR1, PARL, MFAP3, TMEM192, FAR2, ARV1, CLPTM1, ABCB6, SLC38A10, SLC26A2, EXT1, PSEN2, TMEM246, AGPAT6, STOM, STARD3, VMP1, ERGIC2, ANKRD13D, ANKRD13A, LMBRD2, TMEM184B, SLC25A17, TMEM223, CHPT1, GK, NDC1, PIGU, BDH1, SFXN5, WRB, TMEM186, PAM16, NR2F2, RER1, YIPF3, SLC16A13, SLC25A46, SGPP1, BSCL2, PTPMT1, DOLK, MTFP1, ALG3, TCTN3, COPG1, ZFPL1, SLC22A6, SPPL2B, VAC14, GPR114, SLC25A6, CHRND, C19orf52, SSR1, SLC39A8, TRAPPC5, TRIM25 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF321P_ERGIC3 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF321P_ERGIC3 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |