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Fusion gene ID: 43198 |
FusionGeneSummary for ZNF318_PDE3A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF318_PDE3A | Fusion gene ID: 43198 | Hgene | Tgene | Gene symbol | ZNF318 | PDE3A | Gene ID | 24149 | 5139 |
| Gene name | zinc finger protein 318 | phosphodiesterase 3A | |
| Synonyms | HRIHFB2436|TZF|ZFP318 | CGI-PDE|CGI-PDE A|CGI-PDE-A|HTNB | |
| Cytomap | 6p21.1 | 12p12.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 318endocrine regulatorendocrine regulatory proteintesticular zinc finger | cGMP-inhibited 3',5'-cyclic phosphodiesterase AcAMP phosphodiesterase, myocardial cGMP-inhibitedcyclic GMP-inhibited phosphodiesterase Aphosphodiesterase 3A, cGMP-inhibited | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q5VUA4 | Q14432 | |
| Ensembl transtripts involved in fusion gene | ENST00000607252, ENST00000318149, ENST00000361428, | ENST00000359062, ENST00000544307, | |
| Fusion gene scores | * DoF score | 6 X 5 X 5=150 | 3 X 2 X 2=12 |
| # samples | 7 | 3 | |
| ** MAII score | log2(7/150*10)=-1.09953567355091 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ZNF318 [Title/Abstract] AND PDE3A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PDE3A | GO:0006198 | cAMP catabolic process | 17704206 |
| Tgene | PDE3A | GO:0071321 | cellular response to cGMP | 17704206 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A18T-01A | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000607252 | ENST00000359062 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| intron-intron | ENST00000607252 | ENST00000544307 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| In-frame | ENST00000318149 | ENST00000359062 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| 5CDS-intron | ENST00000318149 | ENST00000544307 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| In-frame | ENST00000361428 | ENST00000359062 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
| 5CDS-intron | ENST00000361428 | ENST00000544307 | ZNF318 | chr6 | 43310414 | - | PDE3A | chr12 | 20709594 | + |
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FusionProtFeatures for ZNF318_PDE3A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF318 | PDE3A |
| Isoform 2: Acts as a transcriptional corepressor for AR-mediated transactivation function. May act as a transcriptionalregulator during spermatogenesis and, in particular, duringmeiotic division. {ECO:0000250|UniProtKB:Q99PP2}. Isoform 1: Acts as a transcriptional coactivator for AR-mediated transactivation function. May act as a transcriptionalregulator during spermatogenesis and, in particular, duringmeiotic division. {ECO:0000250|UniProtKB:Q99PP2}. | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are keyregulators of many important physiological processes.{ECO:0000250|UniProtKB:Q9Z0X4}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF318_PDE3A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZNF318_ENST00000318149_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_1914aa MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSP SPPRGRRLFPPGPAGFRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLED MDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHISCHDELLRGTERNREKLKGYSIRSEERSRE AKRPRYDDTVKINSMGGDHPSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTA SEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLPLSGAIAAFASEIENKGTMVETALKEPQGNL YQWGPLPGIPKDNSPLREKFGSFLCHKDNLDLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYG DEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIGLDIGVAEISQLAARTQERLHGKKPSLRSSA DRRSSVDRYFSADHCSSVDHRFSADRCSSVDHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVG HISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPTSQP SNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN DREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQK SLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD FFTHMHNKKHTQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPV TSLSENYTCSDSEESSEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWNNPVMMTLT KSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQI LTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYAPETMMFLD KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHAT DVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFL VATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDR LLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVE DSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQA >In-frame_ZNF318_ENST00000361428_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_1914aa MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSP SPPRGRRLFPPGPAGFRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLED MDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHISCHDELLRGTERNREKLKGYSIRSEERSRE AKRPRYDDTVKINSMGGDHPSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTA SEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLPLSGAIAAFASEIENKGTMVETALKEPQGNL YQWGPLPGIPKDNSPLREKFGSFLCHKDNLDLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYG DEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIGLDIGVAEISQLAARTQERLHGKKPSLRSSA DRRSSVDRYFSADHCSSVDHRFSADRCSSVDHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVG HISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPTSQP SNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKN DREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQK SLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFD FFTHMHNKKHTQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPV TSLSENYTCSDSEESSEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWNNPVMMTLT KSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQI LTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYAPETMMFLD KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHAT DVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFL VATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDR LLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVE DSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZNF318_ENST00000318149_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_5742nt ATGTACCGCAGCAGCGCTCGCTCCTCCGTCTCTTCCCACCGGCCTAAAGACGACGGCGGGGGCGGCCCGCGCAGCGGCCGCAGCTCTGGC TCCTCCTCAGGCCCGGCTCGCCGCAGCTCACCGCCGCCTCCGCCCTCCGGCTCCTCGTCGCGGACCCCGGCTCGCCGACCCCGCTCGCCC TCAGGGCACCGCGGCCGCCGGGCCTCGCCGTCCCCGCCACGGGGTCGTCGCGTCTCCCCGTCCCCGCCTCGGGCCCGTCGCGGCTCCCCG TCGCCACCGCGGGGCCGACGACTCTTCCCGCCGGGCCCGGCCGGCTTCAGAGGCAGCAGCCGGGGGGAGTCCCGCGCCGACTATGCCCGG GACGGCCGCGGAGACCATCCAGGCGACAGCGGCAGCCGGAGACGCTCTCCTGGTCTGTGTTCTGACTCTTTGGAAAAGAGCTTAAGGATC ACTGTTGGCAATGACCACTTCTGTGTTAGCACACCAGAACGGCGACGGCTTAGTGATCGGCTGGGGTCACCAGTGGATAATCTGGAAGAC ATGGACAGGGATGACCTGACTGATGATTCTGTCTTCACTCGAAGCTCCCAGTGCTCTCGGGGTCTTGAGCGATATATTTCCCAGGAGGAA GGGCCTCTCAGTCCCTTCTTGGGACAACTTGATGAGGACTACCGAACAAAAGAAACTTTCCTGCATCGATCTGATTATAGTCCCCATATC AGTTGTCATGATGAGCTGTTGCGGGGAACAGAACGGAATCGAGAAAAACTCAAAGGCTACTCCATACGATCTGAAGAAAGGAGCCGGGAG GCCAAAAGACCCCGTTATGATGACACAGTGAAGATAAACAGCATGGGAGGGGATCACCCAAGTTTTACATCAGGAACTCGCAACTATCGA CAGCGTAGAAGAAGCCCAAGTCCTAGGTTTCTCGACCCTGAGTTTCGAGAACTGGATCTTGCCAGACGAAAGCGAGAGGAAGAGGAGGAG CGAAGTAGGAGCTTGAGTCAGGAGCTGGTTGGAGTTGATGGTGGTGGTACTGGCTGTTCCATCCCTGGATTGTCAGGTGTCCTAACAGCA TCGGAGCCAGGATATTCTTTGCATCGGCCTGAGGAAGTATCTGTGATGCCCAAGAAATCCATTTTGAAGAAGCGGATTGAGGTGGACATA ATGGAGCCCTCCATGCAGCTTGAGAGTTTTTCCAGCAGTACCAGCTCCAGCCAGGATCACCCTCTCTACTCTGGGCACCCATCCCTTCCA CTAAGTGGTGCTATTGCTGCTTTTGCCTCAGAGATTGAAAACAAGGGGACTATGGTAGAGACTGCCTTGAAGGAACCTCAGGGCAACCTC TACCAATGGGGTCCCCTTCCTGGGATTCCCAAAGACAACAGTCCTCTCAGAGAAAAATTTGGAAGTTTTCTATGCCACAAGGATAATTTG GATTTGAAGGCTGAGGGACCTGAGCGACACACAGACTTCCTGCTGCCCCATGAGAGAGCTAGCCAGGATGGCAGTGGTTTTTCCCGCATT CTGAGCATGTTGGCTGATTCTACCAGTACACAGGAAAAAAGGCGACGTAGCTTTCCCGACATTGAAGATGAGGAGAAATTTCTCTATGGG GATGAAGAAGAGGATTTAAAGGCAGAATCCGTACCAAAGCCCCTTGGGAGCTCTGAGAGTGAAGTTATGAGGCAGAAGGCAAGCTCCCTG CCGTCTTCAGCTCCAGCTGTAAAGCTAGAATCACTAGAAGAGACCAATCCAGAATATGCGAAGATCCATGACTTGCTCAAGACAATAGGG CTGGATATTGGAGTAGCAGAGATTAGTCAATTGGCTGCACGCACCCAGGAACGACTTCATGGCAAGAAGCCATCATTACGCTCCTCAGCT GACCGCCGTTCCTCAGTTGACCGATACTTTTCAGCTGACCACTGTTCCTCAGTTGACCACCGCTTCTCAGCTGACCGCTGTTCCTCAGTT GACCACTGCTTCTCAGCTGATCGACGTTCCTCAGATCCCCACAGACTAGAGAGCAGGGAGGCACATCATAGCAATACCCACTCTCCAGAG GTGTCCCATCCACACCCACCTTCTCCTGTGGATCCTTACCTGCTCACAAAAAACAGCCCTCCATTCCTAAAGTCTGACCATCCAGTGGGT CATATTTCAGGACCAGAGGTGGTTGGTAGTGGGTTTCAGTCATCTGTTGCAGTCAGGTGCATGTTGCCATCAGCCCCATCTGCCCCAATT AGACTTCCACACACTGCTGCTTTATCTCAGTTTCACATGCCAAGGGCCTCTCAGTTTGCTGCAGCTCGGATACCTCCGAACTACCAGGGA CCTGCCATTCCCCCTGCCTCTTTTGATGCCTATAGGCACTACATGGCATATGCAGCCTCCAGATGGCCCATGTATCCCACCTCTCAACCG TCAAACCACCCTGTACCTGAACCACACAGGATAATGCCAATAACCAAACAAGCTACTCGTAGCCGTCCCAATCTTCGTGTGATCCCCACT GTGACTCCTGATAAGCCTAAGCAGAAAGAGTCTCTGCGAGGCTCAATTCCTGCGGCCCAAGTGCCTGTCCAGGTGTCCATTCCATCACTC ATAAGATATAATCCAGAGAAGATCTCTGATGAGAAGAACCGTGCTTCCCAGAAGCAAAAGGTTATTGAAGAGAGGGAAAAACTAAAGAAT GACCGGGAAGCCCGCCAGAAGAAGATGTACTATCTTAGGACCGAGTTAGAGCGGCTTCATAAACAACAAGGAGAAATGCTGCGCAAGAAA CGAAGGGAGAAGGATGGCCACAAAGATCCTCTCTTGGTGGAGGTGAGTCGGCTTCAGGATAACATTATGAAGGACATTGCAGAGCTACGG CAAGAGGCAGAAGAGGCAGAAAAGAAGCAATCTGAACTGGACAAAGTGGCTCAGATCTTGGGAATTAACATCTTCGATAAATCCCAGAAG TCTTTAAGTGACAGTAGAGAGCCTACAGAGAAGCCTGGGAAAGCAGAAAAATCTAAGAGCCCAGAAAAAGTGTCATCGTTCTCAAACTCC TCCTCCAACAAGGAATCAAAAGTAAACAATGAGAAGTTTCGTACTAAGAGCCCCAAGCCTGCCGAAAGCCCCCAGTCAGCCACTAAGCAG TTGGATCAGCCCACTGCTGCTTATGAGTATTATGATGCTGGCAATCACTGGTGCAAAGACTGCAACACCATCTGTGGGACCATGTTTGAT TTCTTCACTCATATGCACAATAAGAAGCACACACAGCTCATGGGGCATTCAGAATGGGACCACAAACGAGGGCCAAGAGGATCACAGTCT TCAGGAACCAGTATTACTGTGGACATCGCCGTCATGGGCGAGGCCCACGGCCTCATTACCGACCTCCTGGCAGACCCTTCTCTTCCACCA AACGTGTGCACATCCTTGAGAGCCGTGAGCAACTTGCTCAGCACACAGCTCACCTTCCAGGCCATTCACAAGCCCAGAGTGAATCCCGTC ACTTCGCTCAGTGAAAACTATACCTGTTCTGACTCTGAAGAGAGCTCTGAAAAAGACAAGCTTGCTATTCCAAAGCGCCTGAGAAGGAGT TTGCCTCCTGGCTTGTTGAGACGAGTTTCTTCCACTTGGACCACCACCACCTCGGCCACAGGTCTACCCACCTTGGAGCCTGCACCAGTA CGGAGAGACCGCAGCACCAGCATCAAACTGCAGGAAGCACCTTCATCCAGTCCTGATTCTTGGAATAATCCAGTGATGATGACCCTCACC AAAAGCAGATCCTTTACTTCATCCTATGCTATTTCTGCAGCTAACCATGTAAAGGCTAAAAAGCAAAGTCGACCAGGTGCCCTCGCTAAA ATTTCACCTCTTTCATCGCCCTGCTCCTCACCTCTCCAAGGGACTCCTGCCAGCAGCCTGGTCAGCAAAATTTCTGCAGTGCAGTTTCCA GAATCTGCTGACACAACTGCCAAACAAAGCCTAGGTTCTCACAGGGCCTTAACTTACACTCAGAGTGCCCCAGACCTATCCCCTCAAATC CTGACTCCACCTGTTATATGTAGCAGCTGTGGCAGACCATATTCCCAAGGGAATCCTGCTGATGAGCCCCTGGAGAGAAGTGGGGTAGCC ACTCGGACACCAAGTAGAACAGATGACACTGCTCAAGTTACCTCTGATTATGAAACCAATAACAACAGTGACAGCAGTGACATTGTACAG AATGAAGATGAAACAGAGTGCCTGAGAGAGCCTCTGAGGAAAGCATCGGCTTGCAGCACCTATGCTCCTGAGACCATGATGTTTCTGGAC AAACCAATTCTTGCTCCCGAACCTCTTGTCATGGATAACCTGGACTCAATTATGGAGCAGCTAAATACTTGGAATTTTCCAATTTTTGAT TTAGTGGAAAATATAGGAAGAAAATGTGGCCGTATTCTTAGTCAGGTATCTTACAGACTTTTTGAAGACATGGGCCTCTTTGAAGCTTTT AAAATTCCAATTAGGGAATTTATGAATTATTTTCATGCTTTGGAGATTGGATATAGGGATATTCCTTATCATAACAGAATCCATGCCACT GATGTTTTACATGCTGTTTGGTATCTTACTACACAGCCTATTCCAGGCCTCTCAACTGTGATTAATGATCATGGTTCAACCAGTGATTCA GATTCTGACAGTGGATTTACACATGGACATATGGGATATGTATTCTCAAAAACGTATAATGTGACAGATGATAAATACGGATGTCTGTCT GGGAATATCCCTGCCTTGGAGTTGATGGCGCTGTATGTGGCTGCAGCCATGCACGATTATGATCATCCAGGAAGGACTAATGCTTTCCTG GTTGCAACTAGTGCTCCTCAGGCGGTGCTATATAACGATCGTTCAGTTTTGGAGAATCATCACGCAGCTGCTGCATGGAATCTTTTCATG TCCCGGCCAGAGTATAACTTCTTAATTAACCTTGACCATGTGGAATTTAAGCATTTCCGTTTCCTTGTCATTGAAGCAATTTTGGCCACT GACCTGAAGAAACACTTTGACTTCGTAGCCAAATTTAATGGCAAGGTAAATGATGATGTTGGAATAGATTGGACCAATGAAAATGATCGT CTACTGGTTTGTCAAATGTGTATAAAGTTGGCTGATATCAATGGTCCAGCTAAATGTAAAGAACTCCATCTTCAGTGGACAGATGGTATT GTCAATGAATTTTATGAACAGGGTGATGAAGAGGCCAGCCTTGGATTACCCATAAGCCCCTTCATGGATCGTTCTGCTCCTCAGCTGGCC AACCTTCAGGAATCCTTCATCTCTCACATTGTGGGGCCTCTGTGCAACTCCTATGATTCAGCAGGACTAATGCCTGGAAAATGGGTGGAA GACAGCGATGAGTCAGGAGATACTGATGACCCAGAAGAAGAGGAGGAAGAAGCACCAGCACCAAATGAAGAGGAAACCTGTGAAAATAAT GAATCTCCAAAAAAGAAGACTTTCAAAAGGAGAAAAATCTACTGCCAAATAACTCAGCACCTCTTACAGAACCACAAGATGTGGAAGAAA GTCATTGAAGAGGAGCAACGGTTGGCAGGCATAGAAAATCAATCCCTGGACCAGACCCCTCAGTCGCACTCTTCAGAACAGATCCAGGCT >In-frame_ZNF318_ENST00000361428_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_5742nt ATGTACCGCAGCAGCGCTCGCTCCTCCGTCTCTTCCCACCGGCCTAAAGACGACGGCGGGGGCGGCCCGCGCAGCGGCCGCAGCTCTGGC TCCTCCTCAGGCCCGGCTCGCCGCAGCTCACCGCCGCCTCCGCCCTCCGGCTCCTCGTCGCGGACCCCGGCTCGCCGACCCCGCTCGCCC TCAGGGCACCGCGGCCGCCGGGCCTCGCCGTCCCCGCCACGGGGTCGTCGCGTCTCCCCGTCCCCGCCTCGGGCCCGTCGCGGCTCCCCG TCGCCACCGCGGGGCCGACGACTCTTCCCGCCGGGCCCGGCCGGCTTCAGAGGCAGCAGCCGGGGGGAGTCCCGCGCCGACTATGCCCGG GACGGCCGCGGAGACCATCCAGGCGACAGCGGCAGCCGGAGACGCTCTCCTGGTCTGTGTTCTGACTCTTTGGAAAAGAGCTTAAGGATC ACTGTTGGCAATGACCACTTCTGTGTTAGCACACCAGAACGGCGACGGCTTAGTGATCGGCTGGGGTCACCAGTGGATAATCTGGAAGAC ATGGACAGGGATGACCTGACTGATGATTCTGTCTTCACTCGAAGCTCCCAGTGCTCTCGGGGTCTTGAGCGATATATTTCCCAGGAGGAA GGGCCTCTCAGTCCCTTCTTGGGACAACTTGATGAGGACTACCGAACAAAAGAAACTTTCCTGCATCGATCTGATTATAGTCCCCATATC AGTTGTCATGATGAGCTGTTGCGGGGAACAGAACGGAATCGAGAAAAACTCAAAGGCTACTCCATACGATCTGAAGAAAGGAGCCGGGAG GCCAAAAGACCCCGTTATGATGACACAGTGAAGATAAACAGCATGGGAGGGGATCACCCAAGTTTTACATCAGGAACTCGCAACTATCGA CAGCGTAGAAGAAGCCCAAGTCCTAGGTTTCTCGACCCTGAGTTTCGAGAACTGGATCTTGCCAGACGAAAGCGAGAGGAAGAGGAGGAG CGAAGTAGGAGCTTGAGTCAGGAGCTGGTTGGAGTTGATGGTGGTGGTACTGGCTGTTCCATCCCTGGATTGTCAGGTGTCCTAACAGCA TCGGAGCCAGGATATTCTTTGCATCGGCCTGAGGAAGTATCTGTGATGCCCAAGAAATCCATTTTGAAGAAGCGGATTGAGGTGGACATA ATGGAGCCCTCCATGCAGCTTGAGAGTTTTTCCAGCAGTACCAGCTCCAGCCAGGATCACCCTCTCTACTCTGGGCACCCATCCCTTCCA CTAAGTGGTGCTATTGCTGCTTTTGCCTCAGAGATTGAAAACAAGGGGACTATGGTAGAGACTGCCTTGAAGGAACCTCAGGGCAACCTC TACCAATGGGGTCCCCTTCCTGGGATTCCCAAAGACAACAGTCCTCTCAGAGAAAAATTTGGAAGTTTTCTATGCCACAAGGATAATTTG GATTTGAAGGCTGAGGGACCTGAGCGACACACAGACTTCCTGCTGCCCCATGAGAGAGCTAGCCAGGATGGCAGTGGTTTTTCCCGCATT CTGAGCATGTTGGCTGATTCTACCAGTACACAGGAAAAAAGGCGACGTAGCTTTCCCGACATTGAAGATGAGGAGAAATTTCTCTATGGG GATGAAGAAGAGGATTTAAAGGCAGAATCCGTACCAAAGCCCCTTGGGAGCTCTGAGAGTGAAGTTATGAGGCAGAAGGCAAGCTCCCTG CCGTCTTCAGCTCCAGCTGTAAAGCTAGAATCACTAGAAGAGACCAATCCAGAATATGCGAAGATCCATGACTTGCTCAAGACAATAGGG CTGGATATTGGAGTAGCAGAGATTAGTCAATTGGCTGCACGCACCCAGGAACGACTTCATGGCAAGAAGCCATCATTACGCTCCTCAGCT GACCGCCGTTCCTCAGTTGACCGATACTTTTCAGCTGACCACTGTTCCTCAGTTGACCACCGCTTCTCAGCTGACCGCTGTTCCTCAGTT GACCACTGCTTCTCAGCTGATCGACGTTCCTCAGATCCCCACAGACTAGAGAGCAGGGAGGCACATCATAGCAATACCCACTCTCCAGAG GTGTCCCATCCACACCCACCTTCTCCTGTGGATCCTTACCTGCTCACAAAAAACAGCCCTCCATTCCTAAAGTCTGACCATCCAGTGGGT CATATTTCAGGACCAGAGGTGGTTGGTAGTGGGTTTCAGTCATCTGTTGCAGTCAGGTGCATGTTGCCATCAGCCCCATCTGCCCCAATT AGACTTCCACACACTGCTGCTTTATCTCAGTTTCACATGCCAAGGGCCTCTCAGTTTGCTGCAGCTCGGATACCTCCGAACTACCAGGGA CCTGCCATTCCCCCTGCCTCTTTTGATGCCTATAGGCACTACATGGCATATGCAGCCTCCAGATGGCCCATGTATCCCACCTCTCAACCG TCAAACCACCCTGTACCTGAACCACACAGGATAATGCCAATAACCAAACAAGCTACTCGTAGCCGTCCCAATCTTCGTGTGATCCCCACT GTGACTCCTGATAAGCCTAAGCAGAAAGAGTCTCTGCGAGGCTCAATTCCTGCGGCCCAAGTGCCTGTCCAGGTGTCCATTCCATCACTC ATAAGATATAATCCAGAGAAGATCTCTGATGAGAAGAACCGTGCTTCCCAGAAGCAAAAGGTTATTGAAGAGAGGGAAAAACTAAAGAAT GACCGGGAAGCCCGCCAGAAGAAGATGTACTATCTTAGGACCGAGTTAGAGCGGCTTCATAAACAACAAGGAGAAATGCTGCGCAAGAAA CGAAGGGAGAAGGATGGCCACAAAGATCCTCTCTTGGTGGAGGTGAGTCGGCTTCAGGATAACATTATGAAGGACATTGCAGAGCTACGG CAAGAGGCAGAAGAGGCAGAAAAGAAGCAATCTGAACTGGACAAAGTGGCTCAGATCTTGGGAATTAACATCTTCGATAAATCCCAGAAG TCTTTAAGTGACAGTAGAGAGCCTACAGAGAAGCCTGGGAAAGCAGAAAAATCTAAGAGCCCAGAAAAAGTGTCATCGTTCTCAAACTCC TCCTCCAACAAGGAATCAAAAGTAAACAATGAGAAGTTTCGTACTAAGAGCCCCAAGCCTGCCGAAAGCCCCCAGTCAGCCACTAAGCAG TTGGATCAGCCCACTGCTGCTTATGAGTATTATGATGCTGGCAATCACTGGTGCAAAGACTGCAACACCATCTGTGGGACCATGTTTGAT TTCTTCACTCATATGCACAATAAGAAGCACACACAGCTCATGGGGCATTCAGAATGGGACCACAAACGAGGGCCAAGAGGATCACAGTCT TCAGGAACCAGTATTACTGTGGACATCGCCGTCATGGGCGAGGCCCACGGCCTCATTACCGACCTCCTGGCAGACCCTTCTCTTCCACCA AACGTGTGCACATCCTTGAGAGCCGTGAGCAACTTGCTCAGCACACAGCTCACCTTCCAGGCCATTCACAAGCCCAGAGTGAATCCCGTC ACTTCGCTCAGTGAAAACTATACCTGTTCTGACTCTGAAGAGAGCTCTGAAAAAGACAAGCTTGCTATTCCAAAGCGCCTGAGAAGGAGT TTGCCTCCTGGCTTGTTGAGACGAGTTTCTTCCACTTGGACCACCACCACCTCGGCCACAGGTCTACCCACCTTGGAGCCTGCACCAGTA CGGAGAGACCGCAGCACCAGCATCAAACTGCAGGAAGCACCTTCATCCAGTCCTGATTCTTGGAATAATCCAGTGATGATGACCCTCACC AAAAGCAGATCCTTTACTTCATCCTATGCTATTTCTGCAGCTAACCATGTAAAGGCTAAAAAGCAAAGTCGACCAGGTGCCCTCGCTAAA ATTTCACCTCTTTCATCGCCCTGCTCCTCACCTCTCCAAGGGACTCCTGCCAGCAGCCTGGTCAGCAAAATTTCTGCAGTGCAGTTTCCA GAATCTGCTGACACAACTGCCAAACAAAGCCTAGGTTCTCACAGGGCCTTAACTTACACTCAGAGTGCCCCAGACCTATCCCCTCAAATC CTGACTCCACCTGTTATATGTAGCAGCTGTGGCAGACCATATTCCCAAGGGAATCCTGCTGATGAGCCCCTGGAGAGAAGTGGGGTAGCC ACTCGGACACCAAGTAGAACAGATGACACTGCTCAAGTTACCTCTGATTATGAAACCAATAACAACAGTGACAGCAGTGACATTGTACAG AATGAAGATGAAACAGAGTGCCTGAGAGAGCCTCTGAGGAAAGCATCGGCTTGCAGCACCTATGCTCCTGAGACCATGATGTTTCTGGAC AAACCAATTCTTGCTCCCGAACCTCTTGTCATGGATAACCTGGACTCAATTATGGAGCAGCTAAATACTTGGAATTTTCCAATTTTTGAT TTAGTGGAAAATATAGGAAGAAAATGTGGCCGTATTCTTAGTCAGGTATCTTACAGACTTTTTGAAGACATGGGCCTCTTTGAAGCTTTT AAAATTCCAATTAGGGAATTTATGAATTATTTTCATGCTTTGGAGATTGGATATAGGGATATTCCTTATCATAACAGAATCCATGCCACT GATGTTTTACATGCTGTTTGGTATCTTACTACACAGCCTATTCCAGGCCTCTCAACTGTGATTAATGATCATGGTTCAACCAGTGATTCA GATTCTGACAGTGGATTTACACATGGACATATGGGATATGTATTCTCAAAAACGTATAATGTGACAGATGATAAATACGGATGTCTGTCT GGGAATATCCCTGCCTTGGAGTTGATGGCGCTGTATGTGGCTGCAGCCATGCACGATTATGATCATCCAGGAAGGACTAATGCTTTCCTG GTTGCAACTAGTGCTCCTCAGGCGGTGCTATATAACGATCGTTCAGTTTTGGAGAATCATCACGCAGCTGCTGCATGGAATCTTTTCATG TCCCGGCCAGAGTATAACTTCTTAATTAACCTTGACCATGTGGAATTTAAGCATTTCCGTTTCCTTGTCATTGAAGCAATTTTGGCCACT GACCTGAAGAAACACTTTGACTTCGTAGCCAAATTTAATGGCAAGGTAAATGATGATGTTGGAATAGATTGGACCAATGAAAATGATCGT CTACTGGTTTGTCAAATGTGTATAAAGTTGGCTGATATCAATGGTCCAGCTAAATGTAAAGAACTCCATCTTCAGTGGACAGATGGTATT GTCAATGAATTTTATGAACAGGGTGATGAAGAGGCCAGCCTTGGATTACCCATAAGCCCCTTCATGGATCGTTCTGCTCCTCAGCTGGCC AACCTTCAGGAATCCTTCATCTCTCACATTGTGGGGCCTCTGTGCAACTCCTATGATTCAGCAGGACTAATGCCTGGAAAATGGGTGGAA GACAGCGATGAGTCAGGAGATACTGATGACCCAGAAGAAGAGGAGGAAGAAGCACCAGCACCAAATGAAGAGGAAACCTGTGAAAATAAT GAATCTCCAAAAAAGAAGACTTTCAAAAGGAGAAAAATCTACTGCCAAATAACTCAGCACCTCTTACAGAACCACAAGATGTGGAAGAAA GTCATTGAAGAGGAGCAACGGTTGGCAGGCATAGAAAATCAATCCCTGGACCAGACCCCTCAGTCGCACTCTTCAGAACAGATCCAGGCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZNF318_ENST00000318149_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_9930nt CTGCGGCGGCGCGCTCCGAGCCTGCGTCTAGGGCGCCCCCGGGTCAGAGCTGTCGCCGTGGCCGCCGCTGCAAGAACCATGTACCGCAGC AGCGCTCGCTCCTCCGTCTCTTCCCACCGGCCTAAAGACGACGGCGGGGGCGGCCCGCGCAGCGGCCGCAGCTCTGGCTCCTCCTCAGGC CCGGCTCGCCGCAGCTCACCGCCGCCTCCGCCCTCCGGCTCCTCGTCGCGGACCCCGGCTCGCCGACCCCGCTCGCCCTCAGGGCACCGC GGCCGCCGGGCCTCGCCGTCCCCGCCACGGGGTCGTCGCGTCTCCCCGTCCCCGCCTCGGGCCCGTCGCGGCTCCCCGTCGCCACCGCGG GGCCGACGACTCTTCCCGCCGGGCCCGGCCGGCTTCAGAGGCAGCAGCCGGGGGGAGTCCCGCGCCGACTATGCCCGGGACGGCCGCGGA GACCATCCAGGCGACAGCGGCAGCCGGAGACGCTCTCCTGGTCTGTGTTCTGACTCTTTGGAAAAGAGCTTAAGGATCACTGTTGGCAAT GACCACTTCTGTGTTAGCACACCAGAACGGCGACGGCTTAGTGATCGGCTGGGGTCACCAGTGGATAATCTGGAAGACATGGACAGGGAT GACCTGACTGATGATTCTGTCTTCACTCGAAGCTCCCAGTGCTCTCGGGGTCTTGAGCGATATATTTCCCAGGAGGAAGGGCCTCTCAGT CCCTTCTTGGGACAACTTGATGAGGACTACCGAACAAAAGAAACTTTCCTGCATCGATCTGATTATAGTCCCCATATCAGTTGTCATGAT GAGCTGTTGCGGGGAACAGAACGGAATCGAGAAAAACTCAAAGGCTACTCCATACGATCTGAAGAAAGGAGCCGGGAGGCCAAAAGACCC CGTTATGATGACACAGTGAAGATAAACAGCATGGGAGGGGATCACCCAAGTTTTACATCAGGAACTCGCAACTATCGACAGCGTAGAAGA AGCCCAAGTCCTAGGTTTCTCGACCCTGAGTTTCGAGAACTGGATCTTGCCAGACGAAAGCGAGAGGAAGAGGAGGAGCGAAGTAGGAGC TTGAGTCAGGAGCTGGTTGGAGTTGATGGTGGTGGTACTGGCTGTTCCATCCCTGGATTGTCAGGTGTCCTAACAGCATCGGAGCCAGGA TATTCTTTGCATCGGCCTGAGGAAGTATCTGTGATGCCCAAGAAATCCATTTTGAAGAAGCGGATTGAGGTGGACATAATGGAGCCCTCC ATGCAGCTTGAGAGTTTTTCCAGCAGTACCAGCTCCAGCCAGGATCACCCTCTCTACTCTGGGCACCCATCCCTTCCACTAAGTGGTGCT ATTGCTGCTTTTGCCTCAGAGATTGAAAACAAGGGGACTATGGTAGAGACTGCCTTGAAGGAACCTCAGGGCAACCTCTACCAATGGGGT CCCCTTCCTGGGATTCCCAAAGACAACAGTCCTCTCAGAGAAAAATTTGGAAGTTTTCTATGCCACAAGGATAATTTGGATTTGAAGGCT GAGGGACCTGAGCGACACACAGACTTCCTGCTGCCCCATGAGAGAGCTAGCCAGGATGGCAGTGGTTTTTCCCGCATTCTGAGCATGTTG GCTGATTCTACCAGTACACAGGAAAAAAGGCGACGTAGCTTTCCCGACATTGAAGATGAGGAGAAATTTCTCTATGGGGATGAAGAAGAG GATTTAAAGGCAGAATCCGTACCAAAGCCCCTTGGGAGCTCTGAGAGTGAAGTTATGAGGCAGAAGGCAAGCTCCCTGCCGTCTTCAGCT CCAGCTGTAAAGCTAGAATCACTAGAAGAGACCAATCCAGAATATGCGAAGATCCATGACTTGCTCAAGACAATAGGGCTGGATATTGGA GTAGCAGAGATTAGTCAATTGGCTGCACGCACCCAGGAACGACTTCATGGCAAGAAGCCATCATTACGCTCCTCAGCTGACCGCCGTTCC TCAGTTGACCGATACTTTTCAGCTGACCACTGTTCCTCAGTTGACCACCGCTTCTCAGCTGACCGCTGTTCCTCAGTTGACCACTGCTTC TCAGCTGATCGACGTTCCTCAGATCCCCACAGACTAGAGAGCAGGGAGGCACATCATAGCAATACCCACTCTCCAGAGGTGTCCCATCCA CACCCACCTTCTCCTGTGGATCCTTACCTGCTCACAAAAAACAGCCCTCCATTCCTAAAGTCTGACCATCCAGTGGGTCATATTTCAGGA CCAGAGGTGGTTGGTAGTGGGTTTCAGTCATCTGTTGCAGTCAGGTGCATGTTGCCATCAGCCCCATCTGCCCCAATTAGACTTCCACAC ACTGCTGCTTTATCTCAGTTTCACATGCCAAGGGCCTCTCAGTTTGCTGCAGCTCGGATACCTCCGAACTACCAGGGACCTGCCATTCCC CCTGCCTCTTTTGATGCCTATAGGCACTACATGGCATATGCAGCCTCCAGATGGCCCATGTATCCCACCTCTCAACCGTCAAACCACCCT GTACCTGAACCACACAGGATAATGCCAATAACCAAACAAGCTACTCGTAGCCGTCCCAATCTTCGTGTGATCCCCACTGTGACTCCTGAT AAGCCTAAGCAGAAAGAGTCTCTGCGAGGCTCAATTCCTGCGGCCCAAGTGCCTGTCCAGGTGTCCATTCCATCACTCATAAGATATAAT CCAGAGAAGATCTCTGATGAGAAGAACCGTGCTTCCCAGAAGCAAAAGGTTATTGAAGAGAGGGAAAAACTAAAGAATGACCGGGAAGCC CGCCAGAAGAAGATGTACTATCTTAGGACCGAGTTAGAGCGGCTTCATAAACAACAAGGAGAAATGCTGCGCAAGAAACGAAGGGAGAAG GATGGCCACAAAGATCCTCTCTTGGTGGAGGTGAGTCGGCTTCAGGATAACATTATGAAGGACATTGCAGAGCTACGGCAAGAGGCAGAA GAGGCAGAAAAGAAGCAATCTGAACTGGACAAAGTGGCTCAGATCTTGGGAATTAACATCTTCGATAAATCCCAGAAGTCTTTAAGTGAC AGTAGAGAGCCTACAGAGAAGCCTGGGAAAGCAGAAAAATCTAAGAGCCCAGAAAAAGTGTCATCGTTCTCAAACTCCTCCTCCAACAAG GAATCAAAAGTAAACAATGAGAAGTTTCGTACTAAGAGCCCCAAGCCTGCCGAAAGCCCCCAGTCAGCCACTAAGCAGTTGGATCAGCCC ACTGCTGCTTATGAGTATTATGATGCTGGCAATCACTGGTGCAAAGACTGCAACACCATCTGTGGGACCATGTTTGATTTCTTCACTCAT ATGCACAATAAGAAGCACACACAGCTCATGGGGCATTCAGAATGGGACCACAAACGAGGGCCAAGAGGATCACAGTCTTCAGGAACCAGT ATTACTGTGGACATCGCCGTCATGGGCGAGGCCCACGGCCTCATTACCGACCTCCTGGCAGACCCTTCTCTTCCACCAAACGTGTGCACA TCCTTGAGAGCCGTGAGCAACTTGCTCAGCACACAGCTCACCTTCCAGGCCATTCACAAGCCCAGAGTGAATCCCGTCACTTCGCTCAGT GAAAACTATACCTGTTCTGACTCTGAAGAGAGCTCTGAAAAAGACAAGCTTGCTATTCCAAAGCGCCTGAGAAGGAGTTTGCCTCCTGGC TTGTTGAGACGAGTTTCTTCCACTTGGACCACCACCACCTCGGCCACAGGTCTACCCACCTTGGAGCCTGCACCAGTACGGAGAGACCGC AGCACCAGCATCAAACTGCAGGAAGCACCTTCATCCAGTCCTGATTCTTGGAATAATCCAGTGATGATGACCCTCACCAAAAGCAGATCC TTTACTTCATCCTATGCTATTTCTGCAGCTAACCATGTAAAGGCTAAAAAGCAAAGTCGACCAGGTGCCCTCGCTAAAATTTCACCTCTT TCATCGCCCTGCTCCTCACCTCTCCAAGGGACTCCTGCCAGCAGCCTGGTCAGCAAAATTTCTGCAGTGCAGTTTCCAGAATCTGCTGAC ACAACTGCCAAACAAAGCCTAGGTTCTCACAGGGCCTTAACTTACACTCAGAGTGCCCCAGACCTATCCCCTCAAATCCTGACTCCACCT GTTATATGTAGCAGCTGTGGCAGACCATATTCCCAAGGGAATCCTGCTGATGAGCCCCTGGAGAGAAGTGGGGTAGCCACTCGGACACCA AGTAGAACAGATGACACTGCTCAAGTTACCTCTGATTATGAAACCAATAACAACAGTGACAGCAGTGACATTGTACAGAATGAAGATGAA ACAGAGTGCCTGAGAGAGCCTCTGAGGAAAGCATCGGCTTGCAGCACCTATGCTCCTGAGACCATGATGTTTCTGGACAAACCAATTCTT GCTCCCGAACCTCTTGTCATGGATAACCTGGACTCAATTATGGAGCAGCTAAATACTTGGAATTTTCCAATTTTTGATTTAGTGGAAAAT ATAGGAAGAAAATGTGGCCGTATTCTTAGTCAGGTATCTTACAGACTTTTTGAAGACATGGGCCTCTTTGAAGCTTTTAAAATTCCAATT AGGGAATTTATGAATTATTTTCATGCTTTGGAGATTGGATATAGGGATATTCCTTATCATAACAGAATCCATGCCACTGATGTTTTACAT GCTGTTTGGTATCTTACTACACAGCCTATTCCAGGCCTCTCAACTGTGATTAATGATCATGGTTCAACCAGTGATTCAGATTCTGACAGT GGATTTACACATGGACATATGGGATATGTATTCTCAAAAACGTATAATGTGACAGATGATAAATACGGATGTCTGTCTGGGAATATCCCT GCCTTGGAGTTGATGGCGCTGTATGTGGCTGCAGCCATGCACGATTATGATCATCCAGGAAGGACTAATGCTTTCCTGGTTGCAACTAGT GCTCCTCAGGCGGTGCTATATAACGATCGTTCAGTTTTGGAGAATCATCACGCAGCTGCTGCATGGAATCTTTTCATGTCCCGGCCAGAG TATAACTTCTTAATTAACCTTGACCATGTGGAATTTAAGCATTTCCGTTTCCTTGTCATTGAAGCAATTTTGGCCACTGACCTGAAGAAA CACTTTGACTTCGTAGCCAAATTTAATGGCAAGGTAAATGATGATGTTGGAATAGATTGGACCAATGAAAATGATCGTCTACTGGTTTGT CAAATGTGTATAAAGTTGGCTGATATCAATGGTCCAGCTAAATGTAAAGAACTCCATCTTCAGTGGACAGATGGTATTGTCAATGAATTT TATGAACAGGGTGATGAAGAGGCCAGCCTTGGATTACCCATAAGCCCCTTCATGGATCGTTCTGCTCCTCAGCTGGCCAACCTTCAGGAA TCCTTCATCTCTCACATTGTGGGGCCTCTGTGCAACTCCTATGATTCAGCAGGACTAATGCCTGGAAAATGGGTGGAAGACAGCGATGAG TCAGGAGATACTGATGACCCAGAAGAAGAGGAGGAAGAAGCACCAGCACCAAATGAAGAGGAAACCTGTGAAAATAATGAATCTCCAAAA AAGAAGACTTTCAAAAGGAGAAAAATCTACTGCCAAATAACTCAGCACCTCTTACAGAACCACAAGATGTGGAAGAAAGTCATTGAAGAG GAGCAACGGTTGGCAGGCATAGAAAATCAATCCCTGGACCAGACCCCTCAGTCGCACTCTTCAGAACAGATCCAGGCTATCAAGGAAGAA GAAGAAGAGAAAGGGAAACCAAGAGGCGAGGAGATACCAACCCAAAAGCCAGACCAGTGACAATGGATAGAATGGGCTGTGTTTCCAAAC AGATTGACTTGTCAAAGACTCTCTTCAAGCCAGCACAACATTTAGACACAACACTGTAGAAATTTGAGATGGGCAAATGGCTATTGCATT TTGGGATTCTTCGCATTTTGTGTGTATATTTTTACAGTGAGGTACATTGTTAAAAACTTTTTGCTCAAAGAAGCTTTCACATTGCAACAC CAGCTTCTAAGGATTTTTTAAGGAGGGAATATATATGTGTGTGTGTATATAAGCTCCCACATAGATACATGTAAAACATATTCACACCCA TGCACGCACACACATACACACTGAAGGCCACGATTGCTGGCTCCACAATTTAGTAACATTTATATTAAGATATATATATAGTGGTCACTG TGATATAATAAATCATAAAGGAAACCAAATCACAAAGGAGATGGTGTGGCTTAGCAAGGAAACAGTGCAGGAAATGTAGGTTACCAACTA AGCAGCTTTTGCTCTTAGTACTGAGGGATGAAAGTTCCAGAGCATTATTTGAATTCTGATACATCCTGCCAACACTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGAAAGAGAGACAGAAGGGAATGGTTTGAGAGGGTGCTTGTGTGCATGTGTGTGCATATGTAA AGAGATTTTTGTGGTTTAAGTAACTCAGAATAGCTGTAGCAAATGACTGAATACATGTGAACAAACAGAAGGAAGTTCACTCTGGAGTGT CTTTGGGAGGCAGCCATTCCAAATGCCCTCCTCCATTTAGCTTCAATAAAGGGCCTTTTGCTGATGGAGGGCACTCAAGGGCTGGGTGAG AGGGCCACGTGTTTGGTATTACATTACTGCTATGCACCACTTGAAGGAGCTCTATCACCAGCCTCAAACCCGAAAGACTGAGGCATTTTC CAGTCTACTTGCCTAATGAATGTATAGGAACTGTCTATGAGTATGGATGTCACTCAACTAAGATCAAATCACCATTTAAGGGGATGGCAT TCTTTATACCTAAACACCTAAGAGCTGAAGTCAGGTCTTTTAATCAGGTTAGAATTCTAAATGATGCCAGAGAAGGCTTGGGAAATTGTA CTTCAGCGTGATAGCCTGTGTCTTCTTAATTTGCTGCAAAATATGTGGTAGAGAAAGAAAAGGAAACAGAAAAATCACTCTGGGTTATAT AGCAAGAGATGAAGGAGAATATTTCAACACAGGGTTTTTGTGTTGACATAGGAAAAGCCTGATTCTTGGCAACTGTTGTAGTTTGTCTTT CAGGGGTGAAGGTCCCACTGACAACCCCTGTTGTGGTGTTCCACACGCTGTTTGTTGGGGTAGCTTCCATCGGCAGTCTGGCCCATTGTC AGTCATGCTTCTTCTGGCCGGGGAGATTATAGAGAGATTGTTTGAAGATTGGGTTATTATTGAAAGTCTTTTTTTTTGTTTGTTTTGTTT TGGTTTGTTTGTTTATCTACACTTGTTTATGCTGTGAGCCAAACCTCTATTTAAAAAGTTGATACTCACTTTCAATATTTTATTTCATAT TATTATATATGTCATGATAGTTATCTTGATGTAAATATGAAGATTTTTTTGTTTCTGTAGATAGTAAACTCTTTTTTTAAAAAAGGAAAA GGGAAACATTTTTATAAAGTTATATTTTAATCACCATTTTTATACATTGTAGTTCTCTCCAAGCCCAGTAAGAGAATGATGATTCATTTG CATGGAGGTCGATGGACAACCAATCATCTACCTTTTCTAATTTAAATGATAATCTGATATAGTTTTATTGCCAGTTAAATGAGGATGCTG CAAAGCATGTTTTTTCACTAGTAACTTTTGCTAACTGAATGAATTCTGGGTCCATATCTCCCAGATGAAAAACTGTTAACCAATACCATA TTTTATAGTTGGTGTCCATTTCTTTCCAACACTGTTTGTTATGATTCTTCCTTGAGTACTTATATACAGACCTGCTCATTATCTAAACAA TCTTACCTTCTAAGTAAACCTTGATTGTGATTTCCAGTTTTTATTTTCTCTGACGTAGTAGAAAGGAATGTTTACATTAAAAATACTTTT GTTTCTCATAAATGGATATTGTACTCCCCCCTTTCAAAGCATTATTTTACAATAATTCATGGCATTTTAAAAAATAAGGCAAAGATAATA CGACAAAAAATATACATGGTTTCAAGGCAAATTCTCCAATAAGTTGGAAAATGTAAAAAGGATCAAGTGGATGCAGCCTCTACCTAAATA ATTAAAATATATTTCAGTATATTTCTGAATTAACACCAGGTCTTCATTATTTAGAACTTACTAAATTGTTTTCATTTTCTTAGTTTTACC TGTGTATCTCCATGTTTGCAAAAATTACTATAAGTCAAATTTTGCCAGTGAATTTAACTATTTTTCTTTCCTTGCAATTAAGGGGAAAAA AGCATTTATCTTATCTTCTCATACCCCTTGCATCTAAGTACTTAGCAAAGTCAATATTTTCCCATTTTCCAAATGCGTCCATCTCTAACA TAAATATTAATTGAACATAGAGCTATGTTTGGAGTGAGTGGACTGGCAGGACAGTTGGAAGTCCATCACAGTCTATTGACAGTTTCATCA AAGCTGTATAGTCCAACTAGTGGGGCAGCTTGGCTACTATGGTGGAAGTCTCAGCAAACTGCCTGGTTTTGTTTGTTTGTTTTGTTTTAA GGTACAGGAAATAAGAGGAATAATAGTGGCCAAAGCAATTAGAACATCTTCATTCCAGAACTGTGTTCAGCAATCCAGGCAGATTGATAC ATTTTTCTTTAAAAATAAATTGCTATTACAGCTAGACGTCAATTGGGATAAATAAAGGGATGAAGATCCACTAAGTTTGTGACTTTCATA CACACCCAGTACATCTCAAAGGATGCTAAGGGACATTTTCTGCCAGTAGAGTTCTCCCCCTTTTTGGTGACAGCAATATTATTATGTTCA CATCTAACTCCAGAGCTTACTTCCTGTGGTGCCAATGTATTTGTTGCAATTTACTACATTTTTATATGAGCCTATTTATAGGTGCCATTA AACTCAGGTCTTTCAAATGAAAGAGTTTCTAGCCCACTTAGGGAAAAAGATAATTGTTTAGAAAACCATAAAATCAATGGTAGGAAAAGT TGGAACTGGTTACCTGGATGCCATGGTTCTCTGTTAAATAAAGTAAGAGACCAGGTGTATTCTGAGTGTCATCAGTGTTATTTTCAGCAT GCTAATAAATGTCTTTCCGGTTATATATCTATCTAAATTAACCTTTAAAATATTGGTTTCCTTGATAAAAGCACCACTTTTGCTTTTGTT AGCTGTAATATTTTTTGTCATTTAGATAAGACCTGGTTTGGCTCTCAATAAAAGATGAAGACAGTAGCTCTGTACAGGGATATATCTATA TTAGTCTTCATCTGATGAATGAAGAAATTTTCTCATATTATGTTCAAGAAAGTATTTACTTCCTAAAAATAGAATTCCCGATTCTGTCTA TTTTGGTTGAATACCAGAACAAATCTTTCCGTTGCAATCCCAGTAAAACGAAAGAAAAGGAATATCTTACAGACTGTTCATATTAGATGT ATGTAGACTGTTAATTTGCAATTTCCCCATATTTCCTGCCTATCTTACCCAGATAACTTTCTTTGAAGGTAAAAGCTGTGCAAAAGGCAT GAGACTCAGGCCTACTCTTTGTTTAAATGATGGAAAAATATAAATTATTTTCTAAGTAATAAAAGTATAAAAATTATCATTATAAATAAA GTCTAAAGTTTGAAATTATTAATTTATAAAAGTGAACTAATTGTGTGATTATCAAATCCTGATTAATGAGAAGTGAATAATCTAAAAATC ATTTATATTCTACTGTGGGAGGTATTCTTGGTGCTTCCATGTCAGTATCGGGCTCTCCATTGTCCTCATCATTTATAGTACTTCTAAAAT AATAATGGAAACCTCAATAAGGGTCTTGTCCTCTTCTGTCATCCTAACCCTGATTCTAGTTTAATGCCTTTCCTGACTTATATGCCATTT >In-frame_ZNF318_ENST00000361428_chr6_43310414_-_PDE3A_ENST00000359062_chr12_20709594_+_9930nt CTGCGGCGGCGCGCTCCGAGCCTGCGTCTAGGGCGCCCCCGGGTCAGAGCTGTCGCCGTGGCCGCCGCTGCAAGAACCATGTACCGCAGC AGCGCTCGCTCCTCCGTCTCTTCCCACCGGCCTAAAGACGACGGCGGGGGCGGCCCGCGCAGCGGCCGCAGCTCTGGCTCCTCCTCAGGC CCGGCTCGCCGCAGCTCACCGCCGCCTCCGCCCTCCGGCTCCTCGTCGCGGACCCCGGCTCGCCGACCCCGCTCGCCCTCAGGGCACCGC GGCCGCCGGGCCTCGCCGTCCCCGCCACGGGGTCGTCGCGTCTCCCCGTCCCCGCCTCGGGCCCGTCGCGGCTCCCCGTCGCCACCGCGG GGCCGACGACTCTTCCCGCCGGGCCCGGCCGGCTTCAGAGGCAGCAGCCGGGGGGAGTCCCGCGCCGACTATGCCCGGGACGGCCGCGGA GACCATCCAGGCGACAGCGGCAGCCGGAGACGCTCTCCTGGTCTGTGTTCTGACTCTTTGGAAAAGAGCTTAAGGATCACTGTTGGCAAT GACCACTTCTGTGTTAGCACACCAGAACGGCGACGGCTTAGTGATCGGCTGGGGTCACCAGTGGATAATCTGGAAGACATGGACAGGGAT GACCTGACTGATGATTCTGTCTTCACTCGAAGCTCCCAGTGCTCTCGGGGTCTTGAGCGATATATTTCCCAGGAGGAAGGGCCTCTCAGT CCCTTCTTGGGACAACTTGATGAGGACTACCGAACAAAAGAAACTTTCCTGCATCGATCTGATTATAGTCCCCATATCAGTTGTCATGAT GAGCTGTTGCGGGGAACAGAACGGAATCGAGAAAAACTCAAAGGCTACTCCATACGATCTGAAGAAAGGAGCCGGGAGGCCAAAAGACCC CGTTATGATGACACAGTGAAGATAAACAGCATGGGAGGGGATCACCCAAGTTTTACATCAGGAACTCGCAACTATCGACAGCGTAGAAGA AGCCCAAGTCCTAGGTTTCTCGACCCTGAGTTTCGAGAACTGGATCTTGCCAGACGAAAGCGAGAGGAAGAGGAGGAGCGAAGTAGGAGC TTGAGTCAGGAGCTGGTTGGAGTTGATGGTGGTGGTACTGGCTGTTCCATCCCTGGATTGTCAGGTGTCCTAACAGCATCGGAGCCAGGA TATTCTTTGCATCGGCCTGAGGAAGTATCTGTGATGCCCAAGAAATCCATTTTGAAGAAGCGGATTGAGGTGGACATAATGGAGCCCTCC ATGCAGCTTGAGAGTTTTTCCAGCAGTACCAGCTCCAGCCAGGATCACCCTCTCTACTCTGGGCACCCATCCCTTCCACTAAGTGGTGCT ATTGCTGCTTTTGCCTCAGAGATTGAAAACAAGGGGACTATGGTAGAGACTGCCTTGAAGGAACCTCAGGGCAACCTCTACCAATGGGGT CCCCTTCCTGGGATTCCCAAAGACAACAGTCCTCTCAGAGAAAAATTTGGAAGTTTTCTATGCCACAAGGATAATTTGGATTTGAAGGCT GAGGGACCTGAGCGACACACAGACTTCCTGCTGCCCCATGAGAGAGCTAGCCAGGATGGCAGTGGTTTTTCCCGCATTCTGAGCATGTTG GCTGATTCTACCAGTACACAGGAAAAAAGGCGACGTAGCTTTCCCGACATTGAAGATGAGGAGAAATTTCTCTATGGGGATGAAGAAGAG GATTTAAAGGCAGAATCCGTACCAAAGCCCCTTGGGAGCTCTGAGAGTGAAGTTATGAGGCAGAAGGCAAGCTCCCTGCCGTCTTCAGCT CCAGCTGTAAAGCTAGAATCACTAGAAGAGACCAATCCAGAATATGCGAAGATCCATGACTTGCTCAAGACAATAGGGCTGGATATTGGA GTAGCAGAGATTAGTCAATTGGCTGCACGCACCCAGGAACGACTTCATGGCAAGAAGCCATCATTACGCTCCTCAGCTGACCGCCGTTCC TCAGTTGACCGATACTTTTCAGCTGACCACTGTTCCTCAGTTGACCACCGCTTCTCAGCTGACCGCTGTTCCTCAGTTGACCACTGCTTC TCAGCTGATCGACGTTCCTCAGATCCCCACAGACTAGAGAGCAGGGAGGCACATCATAGCAATACCCACTCTCCAGAGGTGTCCCATCCA CACCCACCTTCTCCTGTGGATCCTTACCTGCTCACAAAAAACAGCCCTCCATTCCTAAAGTCTGACCATCCAGTGGGTCATATTTCAGGA CCAGAGGTGGTTGGTAGTGGGTTTCAGTCATCTGTTGCAGTCAGGTGCATGTTGCCATCAGCCCCATCTGCCCCAATTAGACTTCCACAC ACTGCTGCTTTATCTCAGTTTCACATGCCAAGGGCCTCTCAGTTTGCTGCAGCTCGGATACCTCCGAACTACCAGGGACCTGCCATTCCC CCTGCCTCTTTTGATGCCTATAGGCACTACATGGCATATGCAGCCTCCAGATGGCCCATGTATCCCACCTCTCAACCGTCAAACCACCCT GTACCTGAACCACACAGGATAATGCCAATAACCAAACAAGCTACTCGTAGCCGTCCCAATCTTCGTGTGATCCCCACTGTGACTCCTGAT AAGCCTAAGCAGAAAGAGTCTCTGCGAGGCTCAATTCCTGCGGCCCAAGTGCCTGTCCAGGTGTCCATTCCATCACTCATAAGATATAAT CCAGAGAAGATCTCTGATGAGAAGAACCGTGCTTCCCAGAAGCAAAAGGTTATTGAAGAGAGGGAAAAACTAAAGAATGACCGGGAAGCC CGCCAGAAGAAGATGTACTATCTTAGGACCGAGTTAGAGCGGCTTCATAAACAACAAGGAGAAATGCTGCGCAAGAAACGAAGGGAGAAG GATGGCCACAAAGATCCTCTCTTGGTGGAGGTGAGTCGGCTTCAGGATAACATTATGAAGGACATTGCAGAGCTACGGCAAGAGGCAGAA GAGGCAGAAAAGAAGCAATCTGAACTGGACAAAGTGGCTCAGATCTTGGGAATTAACATCTTCGATAAATCCCAGAAGTCTTTAAGTGAC AGTAGAGAGCCTACAGAGAAGCCTGGGAAAGCAGAAAAATCTAAGAGCCCAGAAAAAGTGTCATCGTTCTCAAACTCCTCCTCCAACAAG GAATCAAAAGTAAACAATGAGAAGTTTCGTACTAAGAGCCCCAAGCCTGCCGAAAGCCCCCAGTCAGCCACTAAGCAGTTGGATCAGCCC ACTGCTGCTTATGAGTATTATGATGCTGGCAATCACTGGTGCAAAGACTGCAACACCATCTGTGGGACCATGTTTGATTTCTTCACTCAT ATGCACAATAAGAAGCACACACAGCTCATGGGGCATTCAGAATGGGACCACAAACGAGGGCCAAGAGGATCACAGTCTTCAGGAACCAGT ATTACTGTGGACATCGCCGTCATGGGCGAGGCCCACGGCCTCATTACCGACCTCCTGGCAGACCCTTCTCTTCCACCAAACGTGTGCACA TCCTTGAGAGCCGTGAGCAACTTGCTCAGCACACAGCTCACCTTCCAGGCCATTCACAAGCCCAGAGTGAATCCCGTCACTTCGCTCAGT GAAAACTATACCTGTTCTGACTCTGAAGAGAGCTCTGAAAAAGACAAGCTTGCTATTCCAAAGCGCCTGAGAAGGAGTTTGCCTCCTGGC TTGTTGAGACGAGTTTCTTCCACTTGGACCACCACCACCTCGGCCACAGGTCTACCCACCTTGGAGCCTGCACCAGTACGGAGAGACCGC AGCACCAGCATCAAACTGCAGGAAGCACCTTCATCCAGTCCTGATTCTTGGAATAATCCAGTGATGATGACCCTCACCAAAAGCAGATCC TTTACTTCATCCTATGCTATTTCTGCAGCTAACCATGTAAAGGCTAAAAAGCAAAGTCGACCAGGTGCCCTCGCTAAAATTTCACCTCTT TCATCGCCCTGCTCCTCACCTCTCCAAGGGACTCCTGCCAGCAGCCTGGTCAGCAAAATTTCTGCAGTGCAGTTTCCAGAATCTGCTGAC ACAACTGCCAAACAAAGCCTAGGTTCTCACAGGGCCTTAACTTACACTCAGAGTGCCCCAGACCTATCCCCTCAAATCCTGACTCCACCT GTTATATGTAGCAGCTGTGGCAGACCATATTCCCAAGGGAATCCTGCTGATGAGCCCCTGGAGAGAAGTGGGGTAGCCACTCGGACACCA AGTAGAACAGATGACACTGCTCAAGTTACCTCTGATTATGAAACCAATAACAACAGTGACAGCAGTGACATTGTACAGAATGAAGATGAA ACAGAGTGCCTGAGAGAGCCTCTGAGGAAAGCATCGGCTTGCAGCACCTATGCTCCTGAGACCATGATGTTTCTGGACAAACCAATTCTT GCTCCCGAACCTCTTGTCATGGATAACCTGGACTCAATTATGGAGCAGCTAAATACTTGGAATTTTCCAATTTTTGATTTAGTGGAAAAT ATAGGAAGAAAATGTGGCCGTATTCTTAGTCAGGTATCTTACAGACTTTTTGAAGACATGGGCCTCTTTGAAGCTTTTAAAATTCCAATT AGGGAATTTATGAATTATTTTCATGCTTTGGAGATTGGATATAGGGATATTCCTTATCATAACAGAATCCATGCCACTGATGTTTTACAT GCTGTTTGGTATCTTACTACACAGCCTATTCCAGGCCTCTCAACTGTGATTAATGATCATGGTTCAACCAGTGATTCAGATTCTGACAGT GGATTTACACATGGACATATGGGATATGTATTCTCAAAAACGTATAATGTGACAGATGATAAATACGGATGTCTGTCTGGGAATATCCCT GCCTTGGAGTTGATGGCGCTGTATGTGGCTGCAGCCATGCACGATTATGATCATCCAGGAAGGACTAATGCTTTCCTGGTTGCAACTAGT GCTCCTCAGGCGGTGCTATATAACGATCGTTCAGTTTTGGAGAATCATCACGCAGCTGCTGCATGGAATCTTTTCATGTCCCGGCCAGAG TATAACTTCTTAATTAACCTTGACCATGTGGAATTTAAGCATTTCCGTTTCCTTGTCATTGAAGCAATTTTGGCCACTGACCTGAAGAAA CACTTTGACTTCGTAGCCAAATTTAATGGCAAGGTAAATGATGATGTTGGAATAGATTGGACCAATGAAAATGATCGTCTACTGGTTTGT CAAATGTGTATAAAGTTGGCTGATATCAATGGTCCAGCTAAATGTAAAGAACTCCATCTTCAGTGGACAGATGGTATTGTCAATGAATTT TATGAACAGGGTGATGAAGAGGCCAGCCTTGGATTACCCATAAGCCCCTTCATGGATCGTTCTGCTCCTCAGCTGGCCAACCTTCAGGAA TCCTTCATCTCTCACATTGTGGGGCCTCTGTGCAACTCCTATGATTCAGCAGGACTAATGCCTGGAAAATGGGTGGAAGACAGCGATGAG TCAGGAGATACTGATGACCCAGAAGAAGAGGAGGAAGAAGCACCAGCACCAAATGAAGAGGAAACCTGTGAAAATAATGAATCTCCAAAA AAGAAGACTTTCAAAAGGAGAAAAATCTACTGCCAAATAACTCAGCACCTCTTACAGAACCACAAGATGTGGAAGAAAGTCATTGAAGAG GAGCAACGGTTGGCAGGCATAGAAAATCAATCCCTGGACCAGACCCCTCAGTCGCACTCTTCAGAACAGATCCAGGCTATCAAGGAAGAA GAAGAAGAGAAAGGGAAACCAAGAGGCGAGGAGATACCAACCCAAAAGCCAGACCAGTGACAATGGATAGAATGGGCTGTGTTTCCAAAC AGATTGACTTGTCAAAGACTCTCTTCAAGCCAGCACAACATTTAGACACAACACTGTAGAAATTTGAGATGGGCAAATGGCTATTGCATT TTGGGATTCTTCGCATTTTGTGTGTATATTTTTACAGTGAGGTACATTGTTAAAAACTTTTTGCTCAAAGAAGCTTTCACATTGCAACAC CAGCTTCTAAGGATTTTTTAAGGAGGGAATATATATGTGTGTGTGTATATAAGCTCCCACATAGATACATGTAAAACATATTCACACCCA TGCACGCACACACATACACACTGAAGGCCACGATTGCTGGCTCCACAATTTAGTAACATTTATATTAAGATATATATATAGTGGTCACTG TGATATAATAAATCATAAAGGAAACCAAATCACAAAGGAGATGGTGTGGCTTAGCAAGGAAACAGTGCAGGAAATGTAGGTTACCAACTA AGCAGCTTTTGCTCTTAGTACTGAGGGATGAAAGTTCCAGAGCATTATTTGAATTCTGATACATCCTGCCAACACTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGAAAGAGAGACAGAAGGGAATGGTTTGAGAGGGTGCTTGTGTGCATGTGTGTGCATATGTAA AGAGATTTTTGTGGTTTAAGTAACTCAGAATAGCTGTAGCAAATGACTGAATACATGTGAACAAACAGAAGGAAGTTCACTCTGGAGTGT CTTTGGGAGGCAGCCATTCCAAATGCCCTCCTCCATTTAGCTTCAATAAAGGGCCTTTTGCTGATGGAGGGCACTCAAGGGCTGGGTGAG AGGGCCACGTGTTTGGTATTACATTACTGCTATGCACCACTTGAAGGAGCTCTATCACCAGCCTCAAACCCGAAAGACTGAGGCATTTTC CAGTCTACTTGCCTAATGAATGTATAGGAACTGTCTATGAGTATGGATGTCACTCAACTAAGATCAAATCACCATTTAAGGGGATGGCAT TCTTTATACCTAAACACCTAAGAGCTGAAGTCAGGTCTTTTAATCAGGTTAGAATTCTAAATGATGCCAGAGAAGGCTTGGGAAATTGTA CTTCAGCGTGATAGCCTGTGTCTTCTTAATTTGCTGCAAAATATGTGGTAGAGAAAGAAAAGGAAACAGAAAAATCACTCTGGGTTATAT AGCAAGAGATGAAGGAGAATATTTCAACACAGGGTTTTTGTGTTGACATAGGAAAAGCCTGATTCTTGGCAACTGTTGTAGTTTGTCTTT CAGGGGTGAAGGTCCCACTGACAACCCCTGTTGTGGTGTTCCACACGCTGTTTGTTGGGGTAGCTTCCATCGGCAGTCTGGCCCATTGTC AGTCATGCTTCTTCTGGCCGGGGAGATTATAGAGAGATTGTTTGAAGATTGGGTTATTATTGAAAGTCTTTTTTTTTGTTTGTTTTGTTT TGGTTTGTTTGTTTATCTACACTTGTTTATGCTGTGAGCCAAACCTCTATTTAAAAAGTTGATACTCACTTTCAATATTTTATTTCATAT TATTATATATGTCATGATAGTTATCTTGATGTAAATATGAAGATTTTTTTGTTTCTGTAGATAGTAAACTCTTTTTTTAAAAAAGGAAAA GGGAAACATTTTTATAAAGTTATATTTTAATCACCATTTTTATACATTGTAGTTCTCTCCAAGCCCAGTAAGAGAATGATGATTCATTTG CATGGAGGTCGATGGACAACCAATCATCTACCTTTTCTAATTTAAATGATAATCTGATATAGTTTTATTGCCAGTTAAATGAGGATGCTG CAAAGCATGTTTTTTCACTAGTAACTTTTGCTAACTGAATGAATTCTGGGTCCATATCTCCCAGATGAAAAACTGTTAACCAATACCATA TTTTATAGTTGGTGTCCATTTCTTTCCAACACTGTTTGTTATGATTCTTCCTTGAGTACTTATATACAGACCTGCTCATTATCTAAACAA TCTTACCTTCTAAGTAAACCTTGATTGTGATTTCCAGTTTTTATTTTCTCTGACGTAGTAGAAAGGAATGTTTACATTAAAAATACTTTT GTTTCTCATAAATGGATATTGTACTCCCCCCTTTCAAAGCATTATTTTACAATAATTCATGGCATTTTAAAAAATAAGGCAAAGATAATA CGACAAAAAATATACATGGTTTCAAGGCAAATTCTCCAATAAGTTGGAAAATGTAAAAAGGATCAAGTGGATGCAGCCTCTACCTAAATA ATTAAAATATATTTCAGTATATTTCTGAATTAACACCAGGTCTTCATTATTTAGAACTTACTAAATTGTTTTCATTTTCTTAGTTTTACC TGTGTATCTCCATGTTTGCAAAAATTACTATAAGTCAAATTTTGCCAGTGAATTTAACTATTTTTCTTTCCTTGCAATTAAGGGGAAAAA AGCATTTATCTTATCTTCTCATACCCCTTGCATCTAAGTACTTAGCAAAGTCAATATTTTCCCATTTTCCAAATGCGTCCATCTCTAACA TAAATATTAATTGAACATAGAGCTATGTTTGGAGTGAGTGGACTGGCAGGACAGTTGGAAGTCCATCACAGTCTATTGACAGTTTCATCA AAGCTGTATAGTCCAACTAGTGGGGCAGCTTGGCTACTATGGTGGAAGTCTCAGCAAACTGCCTGGTTTTGTTTGTTTGTTTTGTTTTAA GGTACAGGAAATAAGAGGAATAATAGTGGCCAAAGCAATTAGAACATCTTCATTCCAGAACTGTGTTCAGCAATCCAGGCAGATTGATAC ATTTTTCTTTAAAAATAAATTGCTATTACAGCTAGACGTCAATTGGGATAAATAAAGGGATGAAGATCCACTAAGTTTGTGACTTTCATA CACACCCAGTACATCTCAAAGGATGCTAAGGGACATTTTCTGCCAGTAGAGTTCTCCCCCTTTTTGGTGACAGCAATATTATTATGTTCA CATCTAACTCCAGAGCTTACTTCCTGTGGTGCCAATGTATTTGTTGCAATTTACTACATTTTTATATGAGCCTATTTATAGGTGCCATTA AACTCAGGTCTTTCAAATGAAAGAGTTTCTAGCCCACTTAGGGAAAAAGATAATTGTTTAGAAAACCATAAAATCAATGGTAGGAAAAGT TGGAACTGGTTACCTGGATGCCATGGTTCTCTGTTAAATAAAGTAAGAGACCAGGTGTATTCTGAGTGTCATCAGTGTTATTTTCAGCAT GCTAATAAATGTCTTTCCGGTTATATATCTATCTAAATTAACCTTTAAAATATTGGTTTCCTTGATAAAAGCACCACTTTTGCTTTTGTT AGCTGTAATATTTTTTGTCATTTAGATAAGACCTGGTTTGGCTCTCAATAAAAGATGAAGACAGTAGCTCTGTACAGGGATATATCTATA TTAGTCTTCATCTGATGAATGAAGAAATTTTCTCATATTATGTTCAAGAAAGTATTTACTTCCTAAAAATAGAATTCCCGATTCTGTCTA TTTTGGTTGAATACCAGAACAAATCTTTCCGTTGCAATCCCAGTAAAACGAAAGAAAAGGAATATCTTACAGACTGTTCATATTAGATGT ATGTAGACTGTTAATTTGCAATTTCCCCATATTTCCTGCCTATCTTACCCAGATAACTTTCTTTGAAGGTAAAAGCTGTGCAAAAGGCAT GAGACTCAGGCCTACTCTTTGTTTAAATGATGGAAAAATATAAATTATTTTCTAAGTAATAAAAGTATAAAAATTATCATTATAAATAAA GTCTAAAGTTTGAAATTATTAATTTATAAAAGTGAACTAATTGTGTGATTATCAAATCCTGATTAATGAGAAGTGAATAATCTAAAAATC ATTTATATTCTACTGTGGGAGGTATTCTTGGTGCTTCCATGTCAGTATCGGGCTCTCCATTGTCCTCATCATTTATAGTACTTCTAAAAT AATAATGGAAACCTCAATAAGGGTCTTGTCCTCTTCTGTCATCCTAACCCTGATTCTAGTTTAATGCCTTTCCTGACTTATATGCCATTT |
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FusionGenePPI for ZNF318_PDE3A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZNF318 | AR, HDAC2, SIRT7, ISG15, PPP1CC, MMS19, MDM2, CCDC8, FBL, CARD8, FAM160B2, PNMA1, LIPH, MIER2, ZBTB46, B9D2, RPGRIP1L, DYNLT1, AP4M1, SGTB, MCM2, SIRT6, CDC16, NCAPH2, IL17RA, C6orf141, BAG4, CCBL1, CELA1, APOBEC3D, PRPF39, ASB3, P4HA3, CPNE2, AP1G2, CORO6 | PDE3A | YWHAQ, ATP6V1B2, CSDE1, GANAB, GMPPB, JUP, MMS19, DPYSL2, MSH2, RANBP6, TRMT1, UBE4B, AKT1, PRKACA, HSPA5, KIF11, FBXO7, CCDC88A, TUBA1C, WDR62, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF318_PDE3A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PDE3A | Q14432 | DB00235 | Milrinone | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB00261 | Anagrelide | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB00277 | Theophylline | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB01223 | Aminophylline | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB01303 | Oxtriphylline | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB01427 | Amrinone | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB08811 | Tofisopam | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved |
| Tgene | PDE3A | Q14432 | DB00922 | Levosimendan | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved|investigational |
| Tgene | PDE3A | Q14432 | DB01166 | Cilostazol | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved|investigational |
| Tgene | PDE3A | Q14432 | DB04880 | Enoximone | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved|investigational |
| Tgene | PDE3A | Q14432 | DB05266 | Ibudilast | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | small molecule | approved|investigational |
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RelatedDiseases for ZNF318_PDE3A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PDE3A | C0027051 | Myocardial Infarction | 1 | CTD_human |
| Tgene | PDE3A | C0040053 | Thrombosis | 1 | CTD_human |
| Tgene | PDE3A | C1862170 | Brachydactyly with hypertension | 1 | CTD_human;ORPHANET;UNIPROT |
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