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Fusion gene ID: 43156 |
FusionGeneSummary for ZNF276_JPH3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF276_JPH3 | Fusion gene ID: 43156 | Hgene | Tgene | Gene symbol | ZNF276 | JPH3 | Gene ID | 92822 | 57338 |
| Gene name | zinc finger protein 276 | junctophilin 3 | |
| Synonyms | CENP-Z|CENPZ|ZADT|ZFP276|ZNF477 | CAGL237|HDL2|JP-3|JP3|TNRC22 | |
| Cytomap | 16q24.3 | 16q24.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 276centromere protein Zzinc finger protein 276 homologzinc finger protein 477zinc finger, AD-type | junctophilin-3junctophilin type 3trinucleotide repeat containing 22 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8N554 | Q8WXH2 | |
| Ensembl transtripts involved in fusion gene | ENST00000446326, ENST00000289816, ENST00000568064, ENST00000443381, | ENST00000284262, ENST00000563609, | |
| Fusion gene scores | * DoF score | 5 X 5 X 3=75 | 5 X 4 X 5=100 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ZNF276 [Title/Abstract] AND JPH3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | OV | TCGA-20-1684-01A | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000446326 | ENST00000284262 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| 5CDS-3UTR | ENST00000446326 | ENST00000563609 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| In-frame | ENST00000289816 | ENST00000284262 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| 5CDS-3UTR | ENST00000289816 | ENST00000563609 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| Frame-shift | ENST00000568064 | ENST00000284262 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| 5CDS-3UTR | ENST00000568064 | ENST00000563609 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| In-frame | ENST00000443381 | ENST00000284262 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
| 5CDS-3UTR | ENST00000443381 | ENST00000563609 | ZNF276 | chr16 | 89790117 | + | JPH3 | chr16 | 87730186 | + |
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FusionProtFeatures for ZNF276_JPH3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF276 | JPH3 |
| May be involved in transcriptional regulation. | Junctophilins contribute to the formation of junctionalmembrane complexes (JMCs) which link the plasma membrane with theendoplasmic or sarcoplasmic reticulum in excitable cells. Providesa structural foundation for functional cross-talk between the cellsurface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neuronsinvolved in motor coordination and memory. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZNF276_JPH3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZNF276_ENST00000289816_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_287aa MGHCRLCHGKFSSRSLRSISERAPGASMERPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRR KPCAKVGAQPPTGAEEGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDYTMDTSSSCKAFLLDS ALAVKWPWDKETAPRLPQHRGWNPGDAPQTSQGRGTGTPVGAETKTLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGLSAYPGGHG >In-frame_ZNF276_ENST00000443381_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_362aa MKRDRLGRFLSPGSSRQCGASDGGGGVSRTRGRPSLSGGPRVDGATARRAWGPVGSCGDAGEDGADEAGAGRALAMGHCRLCHGKFSSRS LRSISERAPGASMERPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRRKPCAKVGAQPPTGAE EGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDYTMDTSSSCKAFLLDSALAVKWPWDKETAPR LPQHRGWNPGDAPQTSQGRGTGTPVGAETKTLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGLSAYPGGHGDLAQHRSRHSVYXLF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZNF276_ENST00000289816_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_862nt ATGGGTCACTGTCGCCTCTGCCACGGGAAGTTTTCCTCGAGAAGCCTGCGCAGCATCTCCGAGAGGGCGCCTGGAGCGAGCATGGAGAGG CCATCCGCAGAGGAGCGCGTGCTCGTACGGGACTTCCAGCGCCTGCTTGGTGTGGCTGTCCGCCAGGACCCCACCTTGTCTCCGTTTGTC TGCAAGAGCTGCCACGCCCAGTTCTACCAGTGCCACAGCCTTCTCAAGTCCTTCCTGCAGAGGGTCAACGCCTCCCCGGCTGGTCGCCGG AAGCCTTGTGCAAAGGTCGGTGCCCAGCCCCCAACAGGGGCAGAGGAGGGAGCGTGTCTGGTGGATCTGATCACATCCAGCCCCCAGTGC CTGCACGGCTTGGTGGGGTGGGTGCATGGACATGCGGCCAGCTGCGGGGCCCTGCCCCACCTTCAGAGGACACTGTCCTCCGAGTACTGC GGCGTCATCCAGGTCGTGTGGGGCTGCGACCAGGGCCACGACTACACCATGGATACCAGCTCCAGCTGCAAGGCCTTCTTGCTGGACAGT GCGCTGGCAGTCAAGTGGCCATGGGACAAAGAGACGGCGCCACGGCTGCCCCAGCACCGAGGGTGGAACCCTGGGGATGCCCCTCAGACC TCCCAGGGTAGAGGGACAGGGACCCCAGTTGGGGCTGAGACCAAGACCCTGCCCAGCACGGATGTGGCCCAGCCTCCTTCGGACAGCGAC GCGGTGGGGCCCAGGTCGGGCTTCCCACCTCAGCCAAGCCTGCCCCTTTGCAGGGCCCCAGGGCTCAGCGCCTATCCTGGTGGTCATGGT >In-frame_ZNF276_ENST00000443381_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_1087nt ATGAAGCGGGACCGGCTGGGCCGCTTCCTGTCTCCTGGGTCGTCCCGACAGTGCGGGGCCTCGGACGGCGGCGGCGGCGTCAGCCGGACT CGGGGCCGCCCTTCCCTTAGCGGTGGGCCGAGGGTGGACGGGGCGACGGCGCGGCGCGCCTGGGGCCCGGTGGGGTCCTGCGGGGACGCG GGCGAGGACGGCGCGGACGAGGCAGGAGCAGGCCGGGCTCTCGCCATGGGTCACTGTCGCCTCTGCCACGGGAAGTTTTCCTCGAGAAGC CTGCGCAGCATCTCCGAGAGGGCGCCTGGAGCGAGCATGGAGAGGCCATCCGCAGAGGAGCGCGTGCTCGTACGGGACTTCCAGCGCCTG CTTGGTGTGGCTGTCCGCCAGGACCCCACCTTGTCTCCGTTTGTCTGCAAGAGCTGCCACGCCCAGTTCTACCAGTGCCACAGCCTTCTC AAGTCCTTCCTGCAGAGGGTCAACGCCTCCCCGGCTGGTCGCCGGAAGCCTTGTGCAAAGGTCGGTGCCCAGCCCCCAACAGGGGCAGAG GAGGGAGCGTGTCTGGTGGATCTGATCACATCCAGCCCCCAGTGCCTGCACGGCTTGGTGGGGTGGGTGCATGGACATGCGGCCAGCTGC GGGGCCCTGCCCCACCTTCAGAGGACACTGTCCTCCGAGTACTGCGGCGTCATCCAGGTCGTGTGGGGCTGCGACCAGGGCCACGACTAC ACCATGGATACCAGCTCCAGCTGCAAGGCCTTCTTGCTGGACAGTGCGCTGGCAGTCAAGTGGCCATGGGACAAAGAGACGGCGCCACGG CTGCCCCAGCACCGAGGGTGGAACCCTGGGGATGCCCCTCAGACCTCCCAGGGTAGAGGGACAGGGACCCCAGTTGGGGCTGAGACCAAG ACCCTGCCCAGCACGGATGTGGCCCAGCCTCCTTCGGACAGCGACGCGGTGGGGCCCAGGTCGGGCTTCCCACCTCAGCCAAGCCTGCCC CTTTGCAGGGCCCCAGGGCTCAGCGCCTATCCTGGTGGTCATGGTGATCTTGCTCAACATCGGAGTCGCCATTCTGTTTATTAACTTTTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZNF276_ENST00000289816_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_2670nt GCACTTCCGGCGACGGGCCCCCTCCGCGCGTACTGCGGGCCCCACGGGTGTTAGTGGCGGGGGCGGCAGAGTCCGGGTGGGTTGTCGCGA CGGAGCCGGGCCTCTTCGCCGTCTTGAGACGGGGCTGGCGAGAAGGGCCCCTCACGGAGTTGCCATGGGCGTCTAACCGCGGCAGCCAGG CCCCTCTCTACGTGAGACCCCGGCCCCCCTCCCCTTTCTGCAGCCCGCCCGCCACCTGCGCGCCGCGTGGCCTCCGCCGGCGCCTGCCCG CCCCGCGCCTCCGTCTCCCACGGAGCAGGCCGGGCTCTCGCCATGGGTCACTGTCGCCTCTGCCACGGGAAGTTTTCCTCGAGAAGCCTG CGCAGCATCTCCGAGAGGGCGCCTGGAGCGAGCATGGAGAGGCCATCCGCAGAGGAGCGCGTGCTCGTACGGGACTTCCAGCGCCTGCTT GGTGTGGCTGTCCGCCAGGACCCCACCTTGTCTCCGTTTGTCTGCAAGAGCTGCCACGCCCAGTTCTACCAGTGCCACAGCCTTCTCAAG TCCTTCCTGCAGAGGGTCAACGCCTCCCCGGCTGGTCGCCGGAAGCCTTGTGCAAAGGTCGGTGCCCAGCCCCCAACAGGGGCAGAGGAG GGAGCGTGTCTGGTGGATCTGATCACATCCAGCCCCCAGTGCCTGCACGGCTTGGTGGGGTGGGTGCATGGACATGCGGCCAGCTGCGGG GCCCTGCCCCACCTTCAGAGGACACTGTCCTCCGAGTACTGCGGCGTCATCCAGGTCGTGTGGGGCTGCGACCAGGGCCACGACTACACC ATGGATACCAGCTCCAGCTGCAAGGCCTTCTTGCTGGACAGTGCGCTGGCAGTCAAGTGGCCATGGGACAAAGAGACGGCGCCACGGCTG CCCCAGCACCGAGGGTGGAACCCTGGGGATGCCCCTCAGACCTCCCAGGGTAGAGGGACAGGGACCCCAGTTGGGGCTGAGACCAAGACC CTGCCCAGCACGGATGTGGCCCAGCCTCCTTCGGACAGCGACGCGGTGGGGCCCAGGTCGGGCTTCCCACCTCAGCCAAGCCTGCCCCTT TGCAGGGCCCCAGGGCTCAGCGCCTATCCTGGTGGTCATGGTGATCTTGCTCAACATCGGAGTCGCCATTCTGTTTATTAACTTTTTCAT CTGATGAGATGTCGCGGTAGCAAAAATAGAGAAAGGGTAGAAAAAAGGGACATTAAAATTAAAAGCAAAACCACAAGAAGGGAAAGACCG CAACTCGGACAGCCCAGCGACTTCCAAGTCCTCTCACAGAAGAACCACACGATTGGGTATCACTCACAGTTTGCCTTTTTTTCTGGGTAA TGTTTTTTGGATTTTAGCCAAAATTCTTTGCTTGTATAACACTCTGCTGTGTGGCATGGCAGAAGGAGGCCAGCACGCAGCCCCTCCAGC TCCACGTGGAGACAGAAGGGATCCCGGCACATCAGTGGTAACAGCGGACGTTGTCCTCGTGGTCACACGTCCCGTCTTGGGTGTGGATGG AGGGCAGCCCGGGGCAGAGCCTCAGCCCCGCGGCCCCTGAGTGGCAGGGCTGACTCCCGTCGACACGAGCTTAGAAAGTGGATTCACTGC TTTCTCTGTCTAGAACAGACGGGTGACAAGTATGGGCAGGAGGCATGGGGCAGGGTGGCCCACCCCAGTGGGCAGTAGCCTGGCCTTTTT CTGTGTGAGATCTGTGCTGCACACCTGAGGGAGGGGGAGGGATCGGCCACCTCCTCCCTGTGAGACGGATGCAGGTCCTTCCCTCTTCTC GGCACTGCCCCCGGCCTTCCATGAGAAGCCGACTCCCCACACCGAGTTTTAAAGCAAAGCCCTTTTCTTCTGCTGCCCACTCACTGTGGG TCCCATTCGGCTGTTTCCCCCACCAGACCCCAGGGAAGCCGGGGCCCACTCCGATCCGCCTGGGCTCAGCTAAGCACGGAAGCCAAGGGG GCTGTGCCGTGGAGCTGGGCTCGCGCCGGGGCTCTGGGTGTGTGCGCTTGGCGTGCAGGGTGGACGCGTGGGGTTCCGTGTCCCCAGCAG TGAGGGCCCTAGAGGACGCCTTCTCCCATGGTTACTGATCTCCACGGGTTTTCACATCTCTGTACTGTGCCTGCCTCAACTTCCCCTAAC AGATATGCATATTCCTTCCAGATGCCTCAGTGCTACACCACAGTGGGCCTGGTCCCAGGACAGGAATGCGGTTCAAACCCAGTGGCTTGA AACTTCCTGAGAAACTGTAGCATATCCAGCCCCCTAAAATGTACAATGTAACTTGTTCAGTCCAACAAAAACAGGTTCCTTATGTTTCTG CCTTCTCCACCAGGGTCGCTCCATCACCCAAACAAAAGAACAAGGTTTGCCAGGATGTCCGAGTGCCCCCTGGCCCTGGCTCTCGTGTGC ATGGACGTGCCTGAGGGGTCCGGGCACGGCCATACGCAGGACCCCTGTGCCCGGGGAGGCGCTGCAGGGATTCCCCATCCGGTCGTCTTG GGGCCAGCCCGTCTTATGGACTCTGCCTTGCTTTGCTTATGTTTAGCTGTTTCTCTGCTACCTTTCGAGCAGACTTCTTTACTACACTGC >In-frame_ZNF276_ENST00000443381_chr16_89790117_+_JPH3_ENST00000284262_chr16_87730186_+_2680nt CTCGCTTCCAGCGCGCCGAGCGGAGCCTAACGCCGGGTCCTCTAGGAACCTCGGGCCGGGCAGCACCCGCGGGATTCTGCTGGCGTCCTC CGCTGCCATGAAGCGGGACCGGCTGGGCCGCTTCCTGTCTCCTGGGTCGTCCCGACAGTGCGGGGCCTCGGACGGCGGCGGCGGCGTCAG CCGGACTCGGGGCCGCCCTTCCCTTAGCGGTGGGCCGAGGGTGGACGGGGCGACGGCGCGGCGCGCCTGGGGCCCGGTGGGGTCCTGCGG GGACGCGGGCGAGGACGGCGCGGACGAGGCAGGAGCAGGCCGGGCTCTCGCCATGGGTCACTGTCGCCTCTGCCACGGGAAGTTTTCCTC GAGAAGCCTGCGCAGCATCTCCGAGAGGGCGCCTGGAGCGAGCATGGAGAGGCCATCCGCAGAGGAGCGCGTGCTCGTACGGGACTTCCA GCGCCTGCTTGGTGTGGCTGTCCGCCAGGACCCCACCTTGTCTCCGTTTGTCTGCAAGAGCTGCCACGCCCAGTTCTACCAGTGCCACAG CCTTCTCAAGTCCTTCCTGCAGAGGGTCAACGCCTCCCCGGCTGGTCGCCGGAAGCCTTGTGCAAAGGTCGGTGCCCAGCCCCCAACAGG GGCAGAGGAGGGAGCGTGTCTGGTGGATCTGATCACATCCAGCCCCCAGTGCCTGCACGGCTTGGTGGGGTGGGTGCATGGACATGCGGC CAGCTGCGGGGCCCTGCCCCACCTTCAGAGGACACTGTCCTCCGAGTACTGCGGCGTCATCCAGGTCGTGTGGGGCTGCGACCAGGGCCA CGACTACACCATGGATACCAGCTCCAGCTGCAAGGCCTTCTTGCTGGACAGTGCGCTGGCAGTCAAGTGGCCATGGGACAAAGAGACGGC GCCACGGCTGCCCCAGCACCGAGGGTGGAACCCTGGGGATGCCCCTCAGACCTCCCAGGGTAGAGGGACAGGGACCCCAGTTGGGGCTGA GACCAAGACCCTGCCCAGCACGGATGTGGCCCAGCCTCCTTCGGACAGCGACGCGGTGGGGCCCAGGTCGGGCTTCCCACCTCAGCCAAG CCTGCCCCTTTGCAGGGCCCCAGGGCTCAGCGCCTATCCTGGTGGTCATGGTGATCTTGCTCAACATCGGAGTCGCCATTCTGTTTATTA ACTTTTTCATCTGATGAGATGTCGCGGTAGCAAAAATAGAGAAAGGGTAGAAAAAAGGGACATTAAAATTAAAAGCAAAACCACAAGAAG GGAAAGACCGCAACTCGGACAGCCCAGCGACTTCCAAGTCCTCTCACAGAAGAACCACACGATTGGGTATCACTCACAGTTTGCCTTTTT TTCTGGGTAATGTTTTTTGGATTTTAGCCAAAATTCTTTGCTTGTATAACACTCTGCTGTGTGGCATGGCAGAAGGAGGCCAGCACGCAG CCCCTCCAGCTCCACGTGGAGACAGAAGGGATCCCGGCACATCAGTGGTAACAGCGGACGTTGTCCTCGTGGTCACACGTCCCGTCTTGG GTGTGGATGGAGGGCAGCCCGGGGCAGAGCCTCAGCCCCGCGGCCCCTGAGTGGCAGGGCTGACTCCCGTCGACACGAGCTTAGAAAGTG GATTCACTGCTTTCTCTGTCTAGAACAGACGGGTGACAAGTATGGGCAGGAGGCATGGGGCAGGGTGGCCCACCCCAGTGGGCAGTAGCC TGGCCTTTTTCTGTGTGAGATCTGTGCTGCACACCTGAGGGAGGGGGAGGGATCGGCCACCTCCTCCCTGTGAGACGGATGCAGGTCCTT CCCTCTTCTCGGCACTGCCCCCGGCCTTCCATGAGAAGCCGACTCCCCACACCGAGTTTTAAAGCAAAGCCCTTTTCTTCTGCTGCCCAC TCACTGTGGGTCCCATTCGGCTGTTTCCCCCACCAGACCCCAGGGAAGCCGGGGCCCACTCCGATCCGCCTGGGCTCAGCTAAGCACGGA AGCCAAGGGGGCTGTGCCGTGGAGCTGGGCTCGCGCCGGGGCTCTGGGTGTGTGCGCTTGGCGTGCAGGGTGGACGCGTGGGGTTCCGTG TCCCCAGCAGTGAGGGCCCTAGAGGACGCCTTCTCCCATGGTTACTGATCTCCACGGGTTTTCACATCTCTGTACTGTGCCTGCCTCAAC TTCCCCTAACAGATATGCATATTCCTTCCAGATGCCTCAGTGCTACACCACAGTGGGCCTGGTCCCAGGACAGGAATGCGGTTCAAACCC AGTGGCTTGAAACTTCCTGAGAAACTGTAGCATATCCAGCCCCCTAAAATGTACAATGTAACTTGTTCAGTCCAACAAAAACAGGTTCCT TATGTTTCTGCCTTCTCCACCAGGGTCGCTCCATCACCCAAACAAAAGAACAAGGTTTGCCAGGATGTCCGAGTGCCCCCTGGCCCTGGC TCTCGTGTGCATGGACGTGCCTGAGGGGTCCGGGCACGGCCATACGCAGGACCCCTGTGCCCGGGGAGGCGCTGCAGGGATTCCCCATCC GGTCGTCTTGGGGCCAGCCCGTCTTATGGACTCTGCCTTGCTTTGCTTATGTTTAGCTGTTTCTCTGCTACCTTTCGAGCAGACTTCTTT |
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FusionGenePPI for ZNF276_JPH3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZNF276 | ZBTB8A, ATXN1, GCC1 | JPH3 | STK24, BGN, PPP1CA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZNF276_JPH3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF276_JPH3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | JPH3 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
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