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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 42983

FusionGeneSummary for ZMYND8_WFDC2

check button Fusion gene summary
Fusion gene informationFusion gene name: ZMYND8_WFDC2
Fusion gene ID: 42983
HgeneTgene
Gene symbol

ZMYND8

WFDC2

Gene ID

23613

10406

Gene namezinc finger MYND-type containing 8WAP four-disulfide core domain 2
SynonymsPRKCBP1|PRO2893|RACK7EDDM4|HE4|WAP5|dJ461P17.6
Cytomap

20q13.12

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionprotein kinase C-binding protein 1CTCL tumor antigen se14-3cutaneous T-cell lymphoma-associated antigen se14-3predicted protein of HQ2893zinc finger MYND domain-containing protein 8WAP four-disulfide core domain protein 2WAP domain containing protein HE4-V4epididymal protein 4epididymal secretory protein E4epididymis-specific, whey-acidic protein type, four-disulfide coremajor epididymis-specific protein E4putative protease in
Modification date2018052620180527
UniProtAcc

Q9ULU4

Q14508

Ensembl transtripts involved in fusion geneENST00000311275, ENST00000360911, 
ENST00000458360, ENST00000262975, 
ENST00000471951, ENST00000352431, 
ENST00000396281, ENST00000446994, 
ENST00000536340, ENST00000355972, 
ENST00000540497, ENST00000461685, 
ENST00000372023, ENST00000468376, 
ENST00000372676, ENST00000217425, 
ENST00000339946, ENST00000488143, 
ENST00000342873, 
Fusion gene scores* DoF score12 X 9 X 6=6484 X 5 X 3=60
# samples 135
** MAII scorelog2(13/648*10)=-2.31748218985617
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZMYND8 [Title/Abstract] AND WFDC2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDUCSTCGA-N7-A4Y8-01AZMYND8chr20

45976600

-WFDC2chr20

44108582

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000311275ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000311275ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000311275ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000311275ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000311275ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000360911ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000360911ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000360911ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000360911ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000360911ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000458360ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000458360ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000458360ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000458360ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000458360ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000262975ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000262975ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000262975ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000262975ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000262975ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000471951ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000471951ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000471951ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000471951ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000471951ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000352431ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000352431ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000352431ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000352431ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000352431ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000396281ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000396281ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000396281ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000396281ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000396281ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000446994ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000446994ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000446994ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000446994ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000446994ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000536340ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000536340ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000536340ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000536340ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000536340ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000355972ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000355972ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000355972ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000355972ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000355972ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000540497ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000540497ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000540497ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000540497ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000540497ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000461685ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000461685ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000461685ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000461685ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000461685ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
Frame-shiftENST00000372023ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000372023ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-intronENST00000372023ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000372023ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
5CDS-3UTRENST00000372023ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
intron-3CDSENST00000468376ENST00000372676ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
intron-intronENST00000468376ENST00000217425ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
intron-intronENST00000468376ENST00000339946ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
intron-3UTRENST00000468376ENST00000488143ZMYND8chr20

45976600

-WFDC2chr20

44108582

+
intron-3UTRENST00000468376ENST00000342873ZMYND8chr20

45976600

-WFDC2chr20

44108582

+

Top

FusionProtFeatures for ZMYND8_WFDC2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ZMYND8

Q9ULU4

WFDC2

Q14508


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneWFDC2chr20:45976600chr20:44108582ENST00000217425+0331_73-9103DomainWAP 1
TgeneWFDC2chr20:45976600chr20:44108582ENST00000217425+0374_123-9103DomainWAP 2
TgeneWFDC2chr20:45976600chr20:44108582ENST00000339946+0331_732696DomainWAP 1
TgeneWFDC2chr20:45976600chr20:44108582ENST00000339946+0374_1232696DomainWAP 2
TgeneWFDC2chr20:45976600chr20:44108582ENST00000342873+0231_73-145-91DomainWAP 1
TgeneWFDC2chr20:45976600chr20:44108582ENST00000342873+0274_123-145-91DomainWAP 2
TgeneWFDC2chr20:45976600chr20:44108582ENST00000372676+1474_12374127DomainWAP 2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-3241089_109281169Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-32443_4781169Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-324838_85481169Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-2221089_109281187Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-22243_4781187Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-222838_85481187Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-2221089_1092281161Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-22243_47281161Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-222838_854281161Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-3241089_109281215Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-32443_4781215Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-324838_85481215Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-2221089_1092281136Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-22243_47281136Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-222838_854281136Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-2231089_1092281189Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-22343_47281189Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-223838_854281189Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-2231089_1092281235Compositional biasNote=Poly-Ser
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-22343_47281235Compositional biasNote=Poly-Lys
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-223838_854281235Compositional biasNote=Poly-Gln
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-324165_23581169DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-324277_32781169DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-222165_23581187DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-222277_32781187DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-222165_235281161DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-222277_327281161DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-324165_23581215DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-324277_32781215DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-222165_235281136DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-222277_327281136DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-223165_235281189DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-223277_327281189DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-223165_235281235DomainBromo
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-223277_327281235DomainPWWP
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-3241028_106281169Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-32488_13381169Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-2221028_106281187Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-22288_13381187Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-2221028_1062281161Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-22288_133281161Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-3241028_106281215Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-32488_13381215Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-2221028_1062281136Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-22288_133281136Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-2231028_1062281189Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-22388_133281189Zinc fingerPHD-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-2231028_1062281235Zinc fingerMYND-type
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-22388_133281235Zinc fingerPHD-type
TgeneWFDC2chr20:45976600chr20:44108582ENST00000372676+1431_7374127DomainWAP 1


Top

FusionGeneSequence for ZMYND8_WFDC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ZMYND8_ENST00000311275_chr20_45976600_-_WFDC2_ENST00000372676_chr20_44108582_+_59aa


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ZMYND8_ENST00000311275_chr20_45976600_-_WFDC2_ENST00000372676_chr20_44108582_+_177nt
ATGGATATCTCTACTCGCTCCAAAGATAAGGAGGGTTCCTGCCCCCAGGTGAACATTAACTTTCCCCAGCTCGGCCTCTGTCGGGACCAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_ZMYND8_ENST00000311275_chr20_45976600_-_WFDC2_ENST00000372676_chr20_44108582_+_594nt
GGAGTGTAGAGGAAATAAAATCATGTCTGTGGCTCATGACAGCATTCCATATTCAGTTGTTGGGTTGTGTTGTTGTTGTTGTGTGTGTTT
TTAATAATACCATGTAACTGTTTAAAAAAATTTCCTTTTTGATCAAGTCCCAAATCTGCCAGCCTGTTCTCTCTTCCTAACTGTGGAAAA
ATGAGACGGTTGCTTGAACATTTGTTGGCTTGGCTGAAGAGGAAATAAAAACAGAACAGGAGGTGGTAGAGGGCATGGATATCTCTACTC
GCTCCAAAGATAAGGAGGGTTCCTGCCCCCAGGTGAACATTAACTTTCCCCAGCTCGGCCTCTGTCGGGACCAGTGCCAGGTGGACAGCC
AGTGTCCTGGCCAGATGAAATGCTGCCGCAATGGCTGTGGGAAGGTGTCCTGTGTCACTCCCAATTTCTGAGCTCCAGCCACCACCAGGC
TGAGCAGTGAGGAGAGAAAGTTTCTGCCTGGCCCTGCATCTGGTTCCAGCCCACCTGCCCTCCCCTTTTTCGGGACTCTGTATTCCCTCT


Top

FusionGenePPI for ZMYND8_WFDC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ZMYND8FHOD1, E2F6, SMARCA4, INTS1, INTS3, INTS5, INTS6, BCL6, CSNK1E, ATN1, RERE, USP7, SUPT4H1, ZFYVE9, SOX2, HDAC1, PBXIP1, ZBTB7A, HECW2, KCTD17, CSNK2A2, CHD4, HDAC2, KRAS, PSMD5, RBBP7, TSPYL1, MBD2, MTA1, MTA2, ZNF592, CHERP, MGA, CDK2AP1, RBM8A, ZNF687, VWA9, KDM5C, RPS27L, ZCCHC17, ESF1, MBD3, GATAD2A, ZNF532, DDX24, GATAD2B, MTA3, TSPYL2, FOXJ2, P4HA3, LLGL2, ZNF408WFDC2PTN, WDR81, PDIA5, WDR91, CRTAC1, PTPRF, EMC4, EIF1AX, GRN, FKBP7, BTBD1, LMNA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-32475_40681169histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-22275_40681187histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-22275_406281161histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-32475_40681215histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-22275_406281136histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-22375_406281189histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-22375_406281235histone H3K14ac
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-32475_26881169histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-22275_26881187histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-22275_268281161histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-32475_26881215histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-22275_268281136histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-22375_268281189histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-22375_268281235histone H3K4me0
HgeneZMYND8chr20:45976600chr20:44108582ENST00000262975-3241147_118681169PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000311275-2221147_118681187PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000352431-2221147_1186281161PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000355972-3241147_118681215PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000360911-2221147_1186281136PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000461685-2231147_1186281189PRKCB1
HgeneZMYND8chr20:45976600chr20:44108582ENST00000471951-2231147_1186281235PRKCB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ZMYND8_WFDC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZMYND8_WFDC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneWFDC2C0023893Liver Cirrhosis, Experimental1CTD_human