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Fusion gene ID: 42945 |
FusionGeneSummary for ZMPSTE24_CAP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZMPSTE24_CAP1 | Fusion gene ID: 42945 | Hgene | Tgene | Gene symbol | ZMPSTE24 | CAP1 | Gene ID | 10269 | 10487 |
| Gene name | zinc metallopeptidase STE24 | cyclase associated actin cytoskeleton regulatory protein 1 | |
| Synonyms | FACE-1|FACE1|HGPS|PRO1|STE24|Ste24p | CAP|CAP1-PEN | |
| Cytomap | 1p34.2 | 1p34.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CAAX prenyl protease 1 homologfarnesylated proteins-converting enzyme 1prenyl protein-specific endoprotease 1zinc metallopeptidase STE24 homologzinc metalloproteinase Ste24 homolog | adenylyl cyclase-associated protein 1CAP, adenylate cyclase-associated protein 1adenylate cyclase associated protein 1testis secretory sperm-binding protein Li 218p | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O75844 | Q01518 | |
| Ensembl transtripts involved in fusion gene | ENST00000372759, ENST00000479131, | ENST00000372797, ENST00000372802, ENST00000372792, ENST00000372798, ENST00000340450, ENST00000372805, ENST00000479759, | |
| Fusion gene scores | * DoF score | 5 X 3 X 5=75 | 7 X 6 X 4=168 |
| # samples | 6 | 8 | |
| ** MAII score | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/168*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ZMPSTE24 [Title/Abstract] AND CAP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-61-1736-01B | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000372759 | ENST00000372797 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| In-frame | ENST00000372759 | ENST00000372802 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| In-frame | ENST00000372759 | ENST00000372792 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| In-frame | ENST00000372759 | ENST00000372798 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| In-frame | ENST00000372759 | ENST00000340450 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| In-frame | ENST00000372759 | ENST00000372805 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| 5CDS-3UTR | ENST00000372759 | ENST00000479759 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000372797 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000372802 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000372792 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000372798 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000340450 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3CDS | ENST00000479131 | ENST00000372805 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
| intron-3UTR | ENST00000479131 | ENST00000479759 | ZMPSTE24 | chr1 | 40737707 | + | CAP1 | chr1 | 40535362 | + |
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FusionProtFeatures for ZMPSTE24_CAP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZMPSTE24 | CAP1 |
| Proteolytically removes the C-terminal three residues offarnesylated proteins. Acts on lamin A/C. | Directly regulates filament dynamics and has beenimplicated in a number of complex developmental and morphologicalprocesses, including mRNA localization and the establishment ofcell polarity. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 103_123 | 256 | 476 | Topological domain | Lumenal |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 145_170 | 256 | 476 | Topological domain | Nuclear |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 192_195 | 256 | 476 | Topological domain | Lumenal |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 1_18 | 256 | 476 | Topological domain | Lumenal |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 40_81 | 256 | 476 | Topological domain | Nuclear |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 124_144 | 256 | 476 | Transmembrane | Helical |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 171_191 | 256 | 476 | Transmembrane | Helical |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 196_216 | 256 | 476 | Transmembrane | Helical |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 19_39 | 256 | 476 | Transmembrane | Helical |
| Hgene | ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 82_102 | 256 | 476 | Transmembrane | Helical |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000340450 | + | 7 | 13 | 319_453 | 268 | 475 | Domain | C-CAP/cofactor C-like |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372792 | + | 7 | 13 | 319_453 | 269 | 476 | Domain | C-CAP/cofactor C-like |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372797 | + | 7 | 13 | 319_453 | 269 | 476 | Domain | C-CAP/cofactor C-like |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372798 | + | 7 | 13 | 319_453 | 268 | 475 | Domain | C-CAP/cofactor C-like |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372802 | + | 7 | 13 | 319_453 | 268 | 475 | Domain | C-CAP/cofactor C-like |
| Tgene | >CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372805 | + | 7 | 13 | 319_453 | 269 | 476 | Domain | C-CAP/cofactor C-like |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 217_347 | 256 | 476 | Topological domain | Nuclear |
| Hgene | >ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 369_382 | 256 | 476 | Topological domain | Lumenal |
| Hgene | >ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 406_475 | 256 | 476 | Topological domain | Nuclear |
| Hgene | >ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 348_368 | 256 | 476 | Transmembrane | Helical |
| Hgene | >ZMPSTE24 | chr1:40737707 | chr1:40535362 | ENST00000372759 | + | 6 | 10 | 383_405 | 256 | 476 | Transmembrane | Helical |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000340450 | + | 7 | 13 | 218_256 | 268 | 475 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000340450 | + | 7 | 13 | 230_241 | 268 | 475 | Compositional bias | Note=Poly-Pro |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372792 | + | 7 | 13 | 218_256 | 269 | 476 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372792 | + | 7 | 13 | 230_241 | 269 | 476 | Compositional bias | Note=Poly-Pro |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372797 | + | 7 | 13 | 218_256 | 269 | 476 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372797 | + | 7 | 13 | 230_241 | 269 | 476 | Compositional bias | Note=Poly-Pro |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372798 | + | 7 | 13 | 218_256 | 268 | 475 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372798 | + | 7 | 13 | 230_241 | 268 | 475 | Compositional bias | Note=Poly-Pro |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372802 | + | 7 | 13 | 218_256 | 268 | 475 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372802 | + | 7 | 13 | 230_241 | 268 | 475 | Compositional bias | Note=Poly-Pro |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372805 | + | 7 | 13 | 218_256 | 269 | 476 | Compositional bias | Note=Ala/Pro/Ser-rich |
| Tgene | CAP1 | chr1:40737707 | chr1:40535362 | ENST00000372805 | + | 7 | 13 | 230_241 | 269 | 476 | Compositional bias | Note=Poly-Pro |
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FusionGeneSequence for ZMPSTE24_CAP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372797_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372802_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372792_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372798_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000340450_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372805_chr1_40535362_+_463aa MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGT LILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEALKHVSDDMKTHKN PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVD NCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372797_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372802_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372792_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372798_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000340450_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372805_chr1_40535362_+_1389nt ATGGGGATGTGGGCATCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTG TATCTTTGGGAGACCTTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGAT TCTGAAACATTTGAGAAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACT CTTATTCTTCTCTTTGGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATC ACTCAGTCCCTGGTGTTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAA GAAAAACATGGCTTCAATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCT GTGTCTTCACTTCTACTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTT CTTGTCACAATCTATGCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTA ATGGCAAAGAGTATTGACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAAC CCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGA GCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAG GACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGAT AACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGT AAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAA TCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372797_chr1_40535362_+_2670nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC ACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTC TTTTCTAGATTTCCTCTACCTTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAG GCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCAT TCTTAAGGAACTGCCGACTAGGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCATTGGAAAGAA AACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTTTTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTT CCAGATGGTTCTTCTAACCAAACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTA GCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTCTATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCT GGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTT CCTATAGAGATGACTTTAAAAGGAAAAAAAAAAAAAAAAAAACCCACATGATTTCAAGGAGTCTGGCATTCCTGAATCCTTCTTCCCTGC CAGGTGCCTGTCACCTGTCTTCACTGCCTCCTTTTCCCTGTCATGCTCATCAGCTTATGGCTTCTGTCTAAGCACCTGAACAGAGGACTG AAACCTCCACTGCAGGCTGGTTTTAGGTCTTGAATTATGTAAGAATCTTGCACAGCACTGCTAATGTAAATTTCAGTTGTTTTTCCCTCT AGGACAAACACTTACCAAAATATGCAACTTTTTTTTGGTGGGAAGAGAGATTGTCCTGTGATTTCTACCCATTTCCTGAGGCCTGTGGAA >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372802_chr1_40535362_+_2536nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC ACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTC TTTTCTAGATTTCCTCTACCTTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAG GCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCAT TCTTAAGGAACTGCCGACTAGGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCATTGGAAAGAA AACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTTTTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTT CCAGATGGTTCTTCTAACCAAACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTA GCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTCTATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCT GGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTT CCTATAGAGATGACTTTAAAAGGAAAAAAAAAAAAAAAAAAACCCACATGATTTCAAGGAGTCTGGCATTCCTGAATCCTTCTTCCCTGC CAGGTGCCTGTCACCTGTCTTCACTGCCTCCTTTTCCCTGTCATGCTCATCAGCTTATGGCTTCTGTCTAAGCACCTGAACAGAGGACTG AAACCTCCACTGCAGGCTGGTTTTAGGTCTTGAATTATGTAAGAATCTTGCACAGCACTGCTAATGTAAATTTCAGTTGTTTTTCCCTCT >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372792_chr1_40535362_+_1556nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372798_chr1_40535362_+_1629nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC ACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTC >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000340450_chr1_40535362_+_2662nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC ACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTC TTTTCTAGATTTCCTCTACCTTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAG GCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCAT TCTTAAGGAACTGCCGACTAGGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCATTGGAAAGAA AACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTTTTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTT CCAGATGGTTCTTCTAACCAAACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTA GCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTCTATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCT GGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTT CCTATAGAGATGACTTTAAAAGGAAAAAAAAAAAAAAAAAAACCCACATGATTTCAAGGAGTCTGGCATTCCTGAATCCTTCTTCCCTGC CAGGTGCCTGTCACCTGTCTTCACTGCCTCCTTTTCCCTGTCATGCTCATCAGCTTATGGCTTCTGTCTAAGCACCTGAACAGAGGACTG AAACCTCCACTGCAGGCTGGTTTTAGGTCTTGAATTATGTAAGAATCTTGCACAGCACTGCTAATGTAAATTTCAGTTGTTTTTCCCTCT AGGACAAACACTTACCAAAATATGCAACTTTTTTTTGGTGGGAAGAGAGATTGTCCTGTGATTTCTACCCATTTCCTGAGGCCTGTGGAA >In-frame_ZMPSTE24_ENST00000372759_chr1_40737707_+_CAP1_ENST00000372805_chr1_40535362_+_2292nt CTGTGACACTGCCAGCAGCGCGCAGAGGGAGGGATGGGGGCGGGTATCGGCGTAGGGGCCCTCGGAAAGAACGGATATTGCTGTGACACC GCGGGGACGCTCTGAAGGGACGAGTGTCGGTGTGGCACCGGTGCACGCTGAAGGAGCCGGCGGAACCGGGTGGCCATGGGGATGTGGGCA TCGCTGGACGCTTTGTGGGAGATGCCGGCCGAGAAGCGTATCTTCGGGGCCGTGCTGCTCTTTTCCTGGACAGTGTATCTTTGGGAGACC TTCCTAGCACAGCGGCAGAGAAGGATATATAAAACAACAACTCATGTACCACCGGAGTTAGGACAGATCATGGATTCTGAAACATTTGAG AAATCTCGACTCTATCAACTGGATAAAAGCACTTTCAGCTTCTGGTCAGGACTCTATTCAGAGACTGAAGGCACTCTTATTCTTCTCTTT GGAGGAATACCTTATCTCTGGAGACTTTCTGGACGGTTCTGTGGTTATGCTGGCTTTGGACCAGAATATGAGATCACTCAGTCCCTGGTG TTTCTGCTGTTGGCTACACTTTTCAGTGCATTGACTGGTTTGCCATGGAGTCTTTATAATACTTTTGTGATAGAAGAAAAACATGGCTTC AATCAACAGACTTTGGGGTTCTTCATGAAAGATGCAATCAAGAAATTTGTTGTGACTCAGTGTATTTTGTTGCCTGTGTCTTCACTTCTA CTTTACATTATTAAAATTGGGGGTGACTATTTTTTTATTTATGCCTGGCTGTTCACATTAGTTGTGTCTCTGGTTCTTGTCACAATCTAT GCTGATTATATTGCCCCTTTATTTGACAAATTCACACCTCTGCCTGAGGGAAAGCTTAAAGAAGAAATTGAAGTAATGGCAAAGAGTATT GACTTTCCTTTGACGAAGGTGTATGTTGTGGAAGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCT CAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAG CCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAA CAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTT GGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATA TCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAAT GTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACC ACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTC TTTTCTAGATTTCCTCTACCTTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAG GCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCAT TCTTAAGGAACTGCCGACTAGGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCATTGGAAAGAA AACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTTTTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTT CCAGATGGTTCTTCTAACCAAACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTA GCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTCTATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCT GGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTT |
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FusionGenePPI for ZMPSTE24_CAP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZMPSTE24 | MME, ELAVL1, DDOST, S100A10, MGST3, ATP6V1H, NDUFB7, TMEM43, UQCRFS1P1, SYNJ2BP, RAB5C, GALNT2, HNRNPF, CD55, MRPS5, VDAC1, HNRNPUL1, KIAA2013, PTPN1, MRPL40, RAB10, BAG3, PMF1, RNF26, CYP1A1, CLTC, TCTN2, TCTN3, SLC18A1, TNFRSF17, GDPD5, VAC14, FDPS, MED21, DEFB4A, GPR21, GTF2E2, SLC17A2, TMPRSS12, SLC2A5, DUSP23, GJB7 | CAP1 | CFL1, CAP1, CAP2, ACTG1, UCHL5, SIRT7, MYOC, PSME2, MYL12A, HTRA2, BARD1, LIG4, FMNL1, FN1, ATF2, ABI2, ACTBL2, HSP90B1, KIAA1598, MCM5, NEK9, SIRT1, TPM4, FASN, HSP90AA1, HSP90AB1, MCM2, MCM3, MCM4, MCM6, MGEA5, TPM3, PLA2G4A, PXN, UFD1L, DPH2, DPYSL2, NPLOC4, RNASEH2C, TTC38, NTRK1, U2AF2, ACTA1, POTEI, BCL7A, TWF2, ACTA2, BCL7C, ACTB, STYX, DLD, G3BP1, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZMPSTE24_CAP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZMPSTE24_CAP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ZMPSTE24 | C1837756 | MANDIBULOACRAL DYSPLASIA WITH TYPE B LIPODYSTROPHY | 3 | CTD_human;ORPHANET;UNIPROT |
| Hgene | ZMPSTE24 | C0917990 | Acro-Osteolysis | 2 | CTD_human |
| Hgene | ZMPSTE24 | C0017668 | Focal glomerulosclerosis | 1 | CTD_human |
| Hgene | ZMPSTE24 | C0023787 | Lipodystrophy | 1 | CTD_human |
| Hgene | ZMPSTE24 | C0024689 | Mandibular Diseases | 1 | CTD_human |
| Hgene | ZMPSTE24 | C0033300 | Progeria | 1 | CTD_human;ORPHANET |
| Hgene | ZMPSTE24 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Hgene | ZMPSTE24 | C1136321 | HIV-Associated Lipodystrophy Syndrome | 1 | CTD_human |
| Tgene | CAP1 | C0029456 | Osteoporosis | 1 | CTD_human |
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