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FusionGeneSummary

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Fusion gene ID: 42798

FusionGeneSummary for ZFHX3_ZMAT4

check button Fusion gene summary
Fusion gene informationFusion gene name: ZFHX3_ZMAT4
Fusion gene ID: 42798
HgeneTgene
Gene symbol

ZFHX3

ZMAT4

Gene ID

463

79698

Gene namezinc finger homeobox 3zinc finger matrin-type 4
SynonymsATBF1|ATBT|ZNF927-
Cytomap

16q22.2-q22.3

8p11.21

Type of geneprotein-codingprotein-coding
Descriptionzinc finger homeobox protein 3AT motif-binding factor 1AT-binding transcription factor 1ZFH-3alpha-fetoprotein enhancer binding proteinzinc finger homeodomain protein 3zinc finger matrin-type protein 4
Modification date2018052320180519
UniProtAcc

Q15911

Q9H898

Ensembl transtripts involved in fusion geneENST00000268489, ENST00000397992, 
ENST00000558842, 		ENST00000315769, 
ENST00000297737, ENST00000523823, 
Fusion gene scores* DoF score12 X 9 X 7=75611 X 7 X 7=539
# samples 1512
** MAII scorelog2(15/756*10)=-2.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/539*10)=-2.16725086714399
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZFHX3 [Title/Abstract] AND ZMAT4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZFHX3

GO:0000122

negative regulation of transcription by RNA polymerase II

11314020

HgeneZFHX3

GO:0045893

positive regulation of transcription, DNA-templated

20599712

HgeneZFHX3

GO:0071559

response to transforming growth factor beta

20599712


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPRADTCGA-G9-7522-01AZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000268489ENST00000315769ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
In-frameENST00000268489ENST00000297737ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
5CDS-intronENST00000268489ENST00000523823ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
In-frameENST00000397992ENST00000315769ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
In-frameENST00000397992ENST00000297737ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
5CDS-intronENST00000397992ENST00000523823ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
intron-3CDSENST00000558842ENST00000315769ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
intron-3CDSENST00000558842ENST00000297737ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-
intron-intronENST00000558842ENST00000523823ZFHX3chr16

72845476

-ZMAT4chr8

40438780

-

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FusionProtFeatures for ZFHX3_ZMAT4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ZFHX3

Q15911

ZMAT4

Q9H898

Transcriptional regulator which can act as an activatoror a repressor. Inhibits the enhancer element of the AFP gene bybinding to its AT-rich core sequence. In concert with SMAD-dependent TGF-beta signaling can repress the transcription of AFPvia its interaction with SMAD2/3 (PubMed:25105025). Regulates thecircadian locomotor rhythms via transcriptional activation ofneuropeptidergic genes which are essential for intercellularsynchrony and rhythm amplitude in the suprachiasmatic nucleus(SCN) of the brain (By similarity). Regulator of myoblastsdifferentiation through the binding to the AT-rich sequence ofMYF6 promoter and promoter repression (PubMed:11312261). Down-regulates the MUC5AC promoter in gastric cancer (PubMed:17330845).In association with RUNX3, upregulates CDKN1A promoter activityfollowing TGF-beta stimulation (PubMed:20599712). Inhibitsestrogen receptor (ESR1) function by selectively competing withcoactivator NCOA3 for binding to ESR1 in ESR1-positive breastcancer cells (PubMed:20720010). {ECO:0000250|UniProtKB:Q61329,ECO:0000269|PubMed:11312261, ECO:0000269|PubMed:17330845,ECO:0000269|PubMed:20599712, ECO:0000269|PubMed:20720010,ECO:0000269|PubMed:25105025}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710104_10712883704Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710460_48912883704Compositional biasNote=Poly-Glu
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710770_78412883704Compositional biasNote=Poly-Ala
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69104_1073742790Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101040_106412883704Zinc fingerC2H2-type 9%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101088_111212883704Zinc fingerC2H2-type 10%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101223_124612883704Zinc fingerC2H2-type 11%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101252_127512883704Zinc fingerC2H2-type 12
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710282_30512883704Zinc fingerC2H2-type 2
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710640_66312883704Zinc fingerC2H2-type 3
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710671_69412883704Zinc fingerC2H2-type 4
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710726_75012883704Zinc fingerC2H2-type 5
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-71079_10112883704Zinc fingerC2H2-type 1%3B degenerate
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710804_82812883704Zinc fingerC2H2-type 6%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710945_96812883704Zinc fingerC2H2-type 7%3B degenerate
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-710984_100812883704Zinc fingerC2H2-type 8%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69282_3053742790Zinc fingerC2H2-type 2
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-6979_1013742790Zinc fingerC2H2-type 1%3B degenerate
TgeneZMAT4chr16:72845476chr8:40438780ENST00000297737-47198_228192230Zinc fingerNote=Matrin-type 4
TgeneZMAT4chr16:72845476chr8:40438780ENST00000315769-36145_175116154Zinc fingerNote=Matrin-type 3
TgeneZMAT4chr16:72845476chr8:40438780ENST00000315769-36198_228116154Zinc fingerNote=Matrin-type 4

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101723_174312883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101789_179412883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101852_185712883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102037_205212883704Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103197_320912883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103210_321412883704Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103227_323112883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103376_338912883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103392_339512883704Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103507_352712883704Compositional biasNote=Poly-Gly
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103597_360012883704Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103636_363912883704Compositional biasNote=Poly-Ser
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691723_17433742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691789_17943742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691852_18573742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692037_20523742790Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693197_32093742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693210_32143742790Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693227_32313742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693376_33893742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693392_33953742790Compositional biasNote=Poly-Gln
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693507_35273742790Compositional biasNote=Poly-Gly
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693597_36003742790Compositional biasNote=Poly-Pro
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693636_36393742790Compositional biasNote=Poly-Ser
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69460_4893742790Compositional biasNote=Poly-Glu
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69770_7843742790Compositional biasNote=Poly-Ala
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102145_220412883704DNA bindingHomeobox 1
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102242_230112883704DNA bindingHomeobox 2
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102641_270012883704DNA bindingHomeobox 3
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102944_300312883704DNA bindingHomeobox 4
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692145_22043742790DNA bindingHomeobox 1
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692242_23013742790DNA bindingHomeobox 2
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692641_27003742790DNA bindingHomeobox 3
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692944_30033742790DNA bindingHomeobox 4
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101360_138512883704Zinc fingerC2H2-type 13
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101401_142312883704Zinc fingerC2H2-type 14
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101429_145212883704Zinc fingerC2H2-type 15
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101545_156912883704Zinc fingerC2H2-type 16
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101596_162012883704Zinc fingerC2H2-type 17
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7101983_200612883704Zinc fingerC2H2-type 18
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102328_235112883704Zinc fingerC2H2-type 19%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102530_255212883704Zinc fingerC2H2-type 20
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7102711_273412883704Zinc fingerC2H2-type 21
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103024_304812883704Zinc fingerC2H2-type 22
HgeneZFHX3chr16:72845476chr8:40438780ENST00000268489-7103529_355312883704Zinc fingerC2H2-type 23
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691040_10643742790Zinc fingerC2H2-type 9%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691088_11123742790Zinc fingerC2H2-type 10%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691223_12463742790Zinc fingerC2H2-type 11%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691252_12753742790Zinc fingerC2H2-type 12
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691360_13853742790Zinc fingerC2H2-type 13
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691401_14233742790Zinc fingerC2H2-type 14
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691429_14523742790Zinc fingerC2H2-type 15
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691545_15693742790Zinc fingerC2H2-type 16
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691596_16203742790Zinc fingerC2H2-type 17
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-691983_20063742790Zinc fingerC2H2-type 18
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692328_23513742790Zinc fingerC2H2-type 19%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692530_25523742790Zinc fingerC2H2-type 20
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-692711_27343742790Zinc fingerC2H2-type 21
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693024_30483742790Zinc fingerC2H2-type 22
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-693529_35533742790Zinc fingerC2H2-type 23
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69640_6633742790Zinc fingerC2H2-type 3
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69671_6943742790Zinc fingerC2H2-type 4
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69726_7503742790Zinc fingerC2H2-type 5
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69804_8283742790Zinc fingerC2H2-type 6%3B atypical
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69945_9683742790Zinc fingerC2H2-type 7%3B degenerate
HgeneZFHX3chr16:72845476chr8:40438780ENST00000397992-69984_10083742790Zinc fingerC2H2-type 8%3B atypical
TgeneZMAT4chr16:72845476chr8:40438780ENST00000297737-47145_175192230Zinc fingerNote=Matrin-type 3
TgeneZMAT4chr16:72845476chr8:40438780ENST00000297737-4714_44192230Zinc fingerNote=Matrin-type 1
TgeneZMAT4chr16:72845476chr8:40438780ENST00000297737-4772_106192230Zinc fingerNote=Matrin-type 2
TgeneZMAT4chr16:72845476chr8:40438780ENST00000315769-3614_44116154Zinc fingerNote=Matrin-type 1
TgeneZMAT4chr16:72845476chr8:40438780ENST00000315769-3672_106116154Zinc fingerNote=Matrin-type 2


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FusionGeneSequence for ZFHX3_ZMAT4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_1325aa
MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNERLAESTASAGPPSEPASKEVTCNECSASFAS
LQTYMEHHCPSARPPPPLREESASDTGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGK
QGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFD
GFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGP
GHSFYGKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGD
CFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL
QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELG
VGECPSGSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYT
CGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCD
YETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMA
AMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCR
YNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESG
VEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPSETAADPEELA
KDQEGGASSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDM

>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_1325aa
MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNERLAESTASAGPPSEPASKEVTCNECSASFAS
LQTYMEHHCPSARPPPPLREESASDTGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSLPGAGGK
QGDPSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFRVFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFD
GFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLVSTANLIGP
GHSFYGKFSGIRMEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGD
CFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL
QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELG
VGECPSGSGVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARGESYT
CGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCD
YETNVARNLRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMDSAASDAQFMMSGFQLDPAGPMA
AMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCR
YNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESG
VEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPSETAADPEELA
KDQEGGASSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDM

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_411aa
MRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCK
TDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCN
YSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEK
ELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHL

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_411aa
MRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCK
TDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCN
YSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPSETAADPEELAKDQEGGASSSQAEK
ELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_3977nt
ATGGAAGGCTGTGACTCGCCCGTCGTCTCGGGGAAGGACAATGGGTGCGGTATCCCTCAGCACCAGCAATGGACTGAACTCAACAGCACC
CACCTCCCTGACAAACCCAGTAGCATGGAGCAGTCCACAGGCGAGAGCCACGGGCCCTTGGACAGCCTGAGGGCCCCCTTCAATGAGCGC
CTCGCGGAGAGCACCGCGTCGGCCGGGCCCCCCTCCGAGCCCGCCAGCAAGGAGGTCACCTGCAACGAATGTTCGGCCTCCTTTGCCAGC
CTCCAGACCTACATGGAGCACCACTGCCCCAGCGCGCGCCCCCCGCCACCCCTGAGAGAGGAGAGCGCCAGCGACACCGGTGAGGAGGGG
GACGAGGAGAGTGACGTGGAGAACCTGGCCGGGGAGATCGTCTACCAGCCGGACGGCTCCGCGTACATTGTGGAGAGCCTGAGCCAGCTG
ACCCAGGGCGGGGGCGCCTGTGGGAGTGGCAGTGGCAGTGGGCCTCTCCCCTCGCTTTTCCTGAACTCTCTCCCTGGCGCGGGGGGCAAG
CAAGGGGACCCTTCGTGTGCTGCACCCGTGTACCCGCAGATCATCAACACTTTCCACATAGCCTCATCCTTCGGGAAATGGTTTGAGGGC
CCAGACCAGGCTTTCCCGAATACCTCAGCCCTGGCGGGGCTCAGCCCCGTCCTGCACAGCTTCCGCGTGTTTGACGTGCGACACAAAAGC
AACAAGGATTACCTGAACAGCGACGGTTCTGCCAAAAGCTCCTGCGTATCCAAAGATGTTCCCAACAATGTGGACCTGTCCAAATTCGAT
GGCTTTGTGCTCTATGGCAAGAGGAAGCCCATCCTGATGTGTTTCTTGTGCAAACTCTCCTTTGGGTACGTCCGTTCGTTTGTGACCCAC
GCGGTGCATGACCATCGAATGACCCTGAGCGAAGACGAGCGGAAAATTCTTAGCAATAAGAACATCTCCGCTATCATCCAAGGGATCGGC
AAAGACAAGGAACCCCTTGTAAGTTTTCTGGAACCAAAAAACAAAAACTTTCAACACCCTTTAGTTTCCACAGCTAACCTCATAGGCCCC
GGACACAGTTTTTATGGTAAATTTAGTGGCATTCGAATGGAAGGGGAGGAAGCTCTCCCAGCGGGCTCCGCCGCTGGCCCCGAGCAGCCC
CAGGCTGGTCTCTTGACCCCCAGCACCCTGTTGAACCTTGGCGGGCTCACCAGCTCGGTACTGAAGACCCCCATTACCTCAGTCCCCCTG
GGGCCTCTGGCTTCCAGTCCTACCAAATCCTCAGAGGGCAAGGACTCTGGGGCGGCAGAAGGAGAGAAGCAGGAAGTGGGCGACGGGGAT
TGCTTCTCTGAGAAGGTAGAGCCAGCCGAAGAGGAGGCGGAGGAGGAAGAGGAGGAGGAAGAGGCGGAGGAGGAGGAGGAAGAAGAGGAG
GAGGAAGAAGAGGAGGAGGAAGACGAGGGTTGCAAAGGACTCTTTCCAAGCGAGTTGGATGAGGAACTGGAGGACAGGCCCCATGAGGAG
CCTGGGGCCGCAGCAGGTAGTAGCAGCAAAAAGGACCTTGCTCTCTCAAACCAAAGCATTTCTAACTCCCCCTTAATGCCTAACGTGCTC
CAGACCCTGTCGAGGGGCACAGCTTCTACTAGTTCTAATTCTGCTTCTTCCTTTGTTGTCTTTGATGGTGCGAACAGGAGGAATCGTTTA
AGCTTTAACAGTGAGGGCGTCAGGGCCAATGTGGCAGAGGGCGGCAGGAGGCTGGACTTCGCTGACGAAAGTGCCAATAAAGACAATGCC
ACAGCACCAGAACCAAATGAAAGCACAGAGGGTGACGATGGGGGCTTCGTTCCCCATCACCAGCACGCTGGCTCCCTCTGCGAGCTTGGG
GTTGGGGAGTGCCCCTCGGGGAGTGGCGTGGAGTGCCCCAAATGCGACACGGTCCTGGGCTCCTCCCGCTCGCTGGGCGGCCACATGACC
ATGATGCATTCTCGTAACTCGTGTAAGACACTCAAGTGCCCCAAGTGCAACTGGCACTATAAGTACCAGCAGACCCTGGAGGCACACATG
AAGGAGAAGCACCCGGAGCCGGGGGGCTCCTGTGTCTACTGCAAAAGCGGGCAGCCCCACCCCCGGCTGGCACGAGGCGAGAGCTACACG
TGTGGTTACAAGCCTTTCCGCTGCGAGGTGTGTAACTACTCCACAACTACCAAAGGCAACCTCAGTATTCATATGCAGTCTGACAAGCAT
CTCAACAACATGCAGAACCTGCAGAATGGAGGGGGGGAGCAGGTCTTCAGCCACACTGCCGGGGCGGCGGCGGCGGCGGTGGCTGCGGCG
GCGGCGGCAGCCAATATCAGTAGCTCCTGCGGGGCCCCCTCGCCGACCAAACCAAAAACCAAACCCACCTGGCGGTGCGAGGTGTGTGAT
TATGAGACCAACGTGGCCAGGAACCTCCGCATTCACATGACCAGTGAGAAGCACATGCATAACATGATGTTACTGCAACAGAACATGACC
CAGATCCAACACAACCGCCACCTGGGCCTCGGCAGCCTGCCCTCACCCGCCGAGGCCGAGCTCTACCAATACTACCTGGCCCAGAACATG
AACCTGCCCAACCTGAAGATGGACAGTGCTGCCTCGGACGCCCAGTTCATGATGAGCGGATTCCAGCTGGATCCCGCCGGGCCCATGGCC
GCCATGACGCCTGCTCTAGTGGGCGGTGAGATCCCCCTAGACATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTG
GGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTCTTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATG
CTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGACGAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGC
TACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAGACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAG
GGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATCGGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAAC
AGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCACGAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGT
GTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAACTACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATG
AAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTGCAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACC
ATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAAGATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCT
AAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAGGAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGT
AGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCTGAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTAC
AGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACGCAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATG
CTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTCCACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGA
GGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACTCAATAGAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCA

>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_3977nt
ATGGAAGGCTGTGACTCGCCCGTCGTCTCGGGGAAGGACAATGGGTGCGGTATCCCTCAGCACCAGCAATGGACTGAACTCAACAGCACC
CACCTCCCTGACAAACCCAGTAGCATGGAGCAGTCCACAGGCGAGAGCCACGGGCCCTTGGACAGCCTGAGGGCCCCCTTCAATGAGCGC
CTCGCGGAGAGCACCGCGTCGGCCGGGCCCCCCTCCGAGCCCGCCAGCAAGGAGGTCACCTGCAACGAATGTTCGGCCTCCTTTGCCAGC
CTCCAGACCTACATGGAGCACCACTGCCCCAGCGCGCGCCCCCCGCCACCCCTGAGAGAGGAGAGCGCCAGCGACACCGGTGAGGAGGGG
GACGAGGAGAGTGACGTGGAGAACCTGGCCGGGGAGATCGTCTACCAGCCGGACGGCTCCGCGTACATTGTGGAGAGCCTGAGCCAGCTG
ACCCAGGGCGGGGGCGCCTGTGGGAGTGGCAGTGGCAGTGGGCCTCTCCCCTCGCTTTTCCTGAACTCTCTCCCTGGCGCGGGGGGCAAG
CAAGGGGACCCTTCGTGTGCTGCACCCGTGTACCCGCAGATCATCAACACTTTCCACATAGCCTCATCCTTCGGGAAATGGTTTGAGGGC
CCAGACCAGGCTTTCCCGAATACCTCAGCCCTGGCGGGGCTCAGCCCCGTCCTGCACAGCTTCCGCGTGTTTGACGTGCGACACAAAAGC
AACAAGGATTACCTGAACAGCGACGGTTCTGCCAAAAGCTCCTGCGTATCCAAAGATGTTCCCAACAATGTGGACCTGTCCAAATTCGAT
GGCTTTGTGCTCTATGGCAAGAGGAAGCCCATCCTGATGTGTTTCTTGTGCAAACTCTCCTTTGGGTACGTCCGTTCGTTTGTGACCCAC
GCGGTGCATGACCATCGAATGACCCTGAGCGAAGACGAGCGGAAAATTCTTAGCAATAAGAACATCTCCGCTATCATCCAAGGGATCGGC
AAAGACAAGGAACCCCTTGTAAGTTTTCTGGAACCAAAAAACAAAAACTTTCAACACCCTTTAGTTTCCACAGCTAACCTCATAGGCCCC
GGACACAGTTTTTATGGTAAATTTAGTGGCATTCGAATGGAAGGGGAGGAAGCTCTCCCAGCGGGCTCCGCCGCTGGCCCCGAGCAGCCC
CAGGCTGGTCTCTTGACCCCCAGCACCCTGTTGAACCTTGGCGGGCTCACCAGCTCGGTACTGAAGACCCCCATTACCTCAGTCCCCCTG
GGGCCTCTGGCTTCCAGTCCTACCAAATCCTCAGAGGGCAAGGACTCTGGGGCGGCAGAAGGAGAGAAGCAGGAAGTGGGCGACGGGGAT
TGCTTCTCTGAGAAGGTAGAGCCAGCCGAAGAGGAGGCGGAGGAGGAAGAGGAGGAGGAAGAGGCGGAGGAGGAGGAGGAAGAAGAGGAG
GAGGAAGAAGAGGAGGAGGAAGACGAGGGTTGCAAAGGACTCTTTCCAAGCGAGTTGGATGAGGAACTGGAGGACAGGCCCCATGAGGAG
CCTGGGGCCGCAGCAGGTAGTAGCAGCAAAAAGGACCTTGCTCTCTCAAACCAAAGCATTTCTAACTCCCCCTTAATGCCTAACGTGCTC
CAGACCCTGTCGAGGGGCACAGCTTCTACTAGTTCTAATTCTGCTTCTTCCTTTGTTGTCTTTGATGGTGCGAACAGGAGGAATCGTTTA
AGCTTTAACAGTGAGGGCGTCAGGGCCAATGTGGCAGAGGGCGGCAGGAGGCTGGACTTCGCTGACGAAAGTGCCAATAAAGACAATGCC
ACAGCACCAGAACCAAATGAAAGCACAGAGGGTGACGATGGGGGCTTCGTTCCCCATCACCAGCACGCTGGCTCCCTCTGCGAGCTTGGG
GTTGGGGAGTGCCCCTCGGGGAGTGGCGTGGAGTGCCCCAAATGCGACACGGTCCTGGGCTCCTCCCGCTCGCTGGGCGGCCACATGACC
ATGATGCATTCTCGTAACTCGTGTAAGACACTCAAGTGCCCCAAGTGCAACTGGCACTATAAGTACCAGCAGACCCTGGAGGCACACATG
AAGGAGAAGCACCCGGAGCCGGGGGGCTCCTGTGTCTACTGCAAAAGCGGGCAGCCCCACCCCCGGCTGGCACGAGGCGAGAGCTACACG
TGTGGTTACAAGCCTTTCCGCTGCGAGGTGTGTAACTACTCCACAACTACCAAAGGCAACCTCAGTATTCATATGCAGTCTGACAAGCAT
CTCAACAACATGCAGAACCTGCAGAATGGAGGGGGGGAGCAGGTCTTCAGCCACACTGCCGGGGCGGCGGCGGCGGCGGTGGCTGCGGCG
GCGGCGGCAGCCAATATCAGTAGCTCCTGCGGGGCCCCCTCGCCGACCAAACCAAAAACCAAACCCACCTGGCGGTGCGAGGTGTGTGAT
TATGAGACCAACGTGGCCAGGAACCTCCGCATTCACATGACCAGTGAGAAGCACATGCATAACATGATGTTACTGCAACAGAACATGACC
CAGATCCAACACAACCGCCACCTGGGCCTCGGCAGCCTGCCCTCACCCGCCGAGGCCGAGCTCTACCAATACTACCTGGCCCAGAACATG
AACCTGCCCAACCTGAAGATGGACAGTGCTGCCTCGGACGCCCAGTTCATGATGAGCGGATTCCAGCTGGATCCCGCCGGGCCCATGGCC
GCCATGACGCCTGCTCTAGTGGGCGGTGAGATCCCCCTAGACATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTG
GGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTCTTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATG
CTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGACGAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGC
TACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAGACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAG
GGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATCGGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAAC
AGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCACGAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGT
GTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAACTACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATG
AAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTGCAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACC
ATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAAGATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCT
AAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAGGAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGT
AGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCTGAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTAC
AGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACGCAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATG
CTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTCCACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGA
GGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACTCAATAGAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCA

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_1235nt
ATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTC
TTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGAC
GAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAG
ACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATC
GGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCAC
GAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAAC
TACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTG
CAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAA
GATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAG
GAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCT
GAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACG
CAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTC
CACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACT

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_1235nt
ATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTC
TTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGAC
GAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAG
ACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATC
GGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCAC
GAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAAC
TACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTG
CAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAA
GATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAG
GAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCT
GAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACG
CAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTC
CACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACT


* Fusion transcript sequences (Full-length transcript).
>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_6283nt
CCGCGCGTCCCTGTGCGTCCCCGGGTCCCTGCGGGCGGGCGGGCGCGGTCGCCGCCGAGCAACCCGGCCTGCGCCCGGCACGACTGTAGA
TGTCAGGCTTTGCCCGGGGAGCCGAGCGGCAGCGGGGCTGTGAGTTTCAAATTAACCTTCCGCTTTGTTGCTGTGTAATGTGGATCCCCG
AAGGCCCCCCGCCCCGCCCGCCCCCCTTCCCCGGGCGGTGCGCGCTGCAAACTGCGAGTTGGGCTTCATTTACATAAAGCGATTCCGGGC
GGGCGGCGGCAGAGGAGGAGGCGGCGGCGGCGGGCAGGCCGGGGACCCGGACGCCAGCGCCGCGCCCCGTGGGTGAATCCCCGCCGCGTC
CCGGGGACCTCCCTCCGGGGACGGGCCGACCGCCAGCCCTGCCGCCACCATGAGCTCCCCTCCCCTGTCTCCGGGCCCCCTGCTCCTGAC
CAGAGCCACCTCCGAGTCCTGGGGCCAGCGGGAGGTGGGGAGCATGCCGCCTGGGGTGGGTGAGCTCGGGGCTCGGGTGCCACTGGAATT
TCCCGTTGTTGCGCATGGCGGCGCGGCCCCCGGACCTGCAAGTGCCGCCTCCCTCCGGAGGTGCGCGGAGGCTTGGTGTGCCAGGTCCGA
GCCTCCGTACTGGGTGCAATGAAAGCTCCACGCAGGCCTTACCATGGAAGGCTGTGACTCGCCCGTCGTCTCGGGGAAGGACAATGGGTG
CGGTATCCCTCAGCACCAGCAATGGACTGAACTCAACAGCACCCACCTCCCTGACAAACCCAGTAGCATGGAGCAGTCCACAGGCGAGAG
CCACGGGCCCTTGGACAGCCTGAGGGCCCCCTTCAATGAGCGCCTCGCGGAGAGCACCGCGTCGGCCGGGCCCCCCTCCGAGCCCGCCAG
CAAGGAGGTCACCTGCAACGAATGTTCGGCCTCCTTTGCCAGCCTCCAGACCTACATGGAGCACCACTGCCCCAGCGCGCGCCCCCCGCC
ACCCCTGAGAGAGGAGAGCGCCAGCGACACCGGTGAGGAGGGGGACGAGGAGAGTGACGTGGAGAACCTGGCCGGGGAGATCGTCTACCA
GCCGGACGGCTCCGCGTACATTGTGGAGAGCCTGAGCCAGCTGACCCAGGGCGGGGGCGCCTGTGGGAGTGGCAGTGGCAGTGGGCCTCT
CCCCTCGCTTTTCCTGAACTCTCTCCCTGGCGCGGGGGGCAAGCAAGGGGACCCTTCGTGTGCTGCACCCGTGTACCCGCAGATCATCAA
CACTTTCCACATAGCCTCATCCTTCGGGAAATGGTTTGAGGGCCCAGACCAGGCTTTCCCGAATACCTCAGCCCTGGCGGGGCTCAGCCC
CGTCCTGCACAGCTTCCGCGTGTTTGACGTGCGACACAAAAGCAACAAGGATTACCTGAACAGCGACGGTTCTGCCAAAAGCTCCTGCGT
ATCCAAAGATGTTCCCAACAATGTGGACCTGTCCAAATTCGATGGCTTTGTGCTCTATGGCAAGAGGAAGCCCATCCTGATGTGTTTCTT
GTGCAAACTCTCCTTTGGGTACGTCCGTTCGTTTGTGACCCACGCGGTGCATGACCATCGAATGACCCTGAGCGAAGACGAGCGGAAAAT
TCTTAGCAATAAGAACATCTCCGCTATCATCCAAGGGATCGGCAAAGACAAGGAACCCCTTGTAAGTTTTCTGGAACCAAAAAACAAAAA
CTTTCAACACCCTTTAGTTTCCACAGCTAACCTCATAGGCCCCGGACACAGTTTTTATGGTAAATTTAGTGGCATTCGAATGGAAGGGGA
GGAAGCTCTCCCAGCGGGCTCCGCCGCTGGCCCCGAGCAGCCCCAGGCTGGTCTCTTGACCCCCAGCACCCTGTTGAACCTTGGCGGGCT
CACCAGCTCGGTACTGAAGACCCCCATTACCTCAGTCCCCCTGGGGCCTCTGGCTTCCAGTCCTACCAAATCCTCAGAGGGCAAGGACTC
TGGGGCGGCAGAAGGAGAGAAGCAGGAAGTGGGCGACGGGGATTGCTTCTCTGAGAAGGTAGAGCCAGCCGAAGAGGAGGCGGAGGAGGA
AGAGGAGGAGGAAGAGGCGGAGGAGGAGGAGGAAGAAGAGGAGGAGGAAGAAGAGGAGGAGGAAGACGAGGGTTGCAAAGGACTCTTTCC
AAGCGAGTTGGATGAGGAACTGGAGGACAGGCCCCATGAGGAGCCTGGGGCCGCAGCAGGTAGTAGCAGCAAAAAGGACCTTGCTCTCTC
AAACCAAAGCATTTCTAACTCCCCCTTAATGCCTAACGTGCTCCAGACCCTGTCGAGGGGCACAGCTTCTACTAGTTCTAATTCTGCTTC
TTCCTTTGTTGTCTTTGATGGTGCGAACAGGAGGAATCGTTTAAGCTTTAACAGTGAGGGCGTCAGGGCCAATGTGGCAGAGGGCGGCAG
GAGGCTGGACTTCGCTGACGAAAGTGCCAATAAAGACAATGCCACAGCACCAGAACCAAATGAAAGCACAGAGGGTGACGATGGGGGCTT
CGTTCCCCATCACCAGCACGCTGGCTCCCTCTGCGAGCTTGGGGTTGGGGAGTGCCCCTCGGGGAGTGGCGTGGAGTGCCCCAAATGCGA
CACGGTCCTGGGCTCCTCCCGCTCGCTGGGCGGCCACATGACCATGATGCATTCTCGTAACTCGTGTAAGACACTCAAGTGCCCCAAGTG
CAACTGGCACTATAAGTACCAGCAGACCCTGGAGGCACACATGAAGGAGAAGCACCCGGAGCCGGGGGGCTCCTGTGTCTACTGCAAAAG
CGGGCAGCCCCACCCCCGGCTGGCACGAGGCGAGAGCTACACGTGTGGTTACAAGCCTTTCCGCTGCGAGGTGTGTAACTACTCCACAAC
TACCAAAGGCAACCTCAGTATTCATATGCAGTCTGACAAGCATCTCAACAACATGCAGAACCTGCAGAATGGAGGGGGGGAGCAGGTCTT
CAGCCACACTGCCGGGGCGGCGGCGGCGGCGGTGGCTGCGGCGGCGGCGGCAGCCAATATCAGTAGCTCCTGCGGGGCCCCCTCGCCGAC
CAAACCAAAAACCAAACCCACCTGGCGGTGCGAGGTGTGTGATTATGAGACCAACGTGGCCAGGAACCTCCGCATTCACATGACCAGTGA
GAAGCACATGCATAACATGATGTTACTGCAACAGAACATGACCCAGATCCAACACAACCGCCACCTGGGCCTCGGCAGCCTGCCCTCACC
CGCCGAGGCCGAGCTCTACCAATACTACCTGGCCCAGAACATGAACCTGCCCAACCTGAAGATGGACAGTGCTGCCTCGGACGCCCAGTT
CATGATGAGCGGATTCCAGCTGGATCCCGCCGGGCCCATGGCCGCCATGACGCCTGCTCTAGTGGGCGGTGAGATCCCCCTAGACATGCG
GCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTCTTCCA
GTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGACGAGTG
GAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAGACAGA
CAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATCGGCAA
CCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCACGAGGC
CAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAACTACTC
CACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTGCAGAA
GGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAAGATGT
TGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAGGAGCT
GACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCTGAGGA
GATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACGCAGCA
CTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTCCACAG
CGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACTCAATA
GAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCAACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAA
ACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCA
CAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGAT
ATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTC
AAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGT
AAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTAT
TAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAG
ACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCA
AGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGT
GAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGG
CCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGG
TCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGT
TCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTG
TAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCT
AACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGA
GCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCA
GGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAA
GGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGT

>In-frame_ZFHX3_ENST00000268489_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_6279nt
CCGCGCGTCCCTGTGCGTCCCCGGGTCCCTGCGGGCGGGCGGGCGCGGTCGCCGCCGAGCAACCCGGCCTGCGCCCGGCACGACTGTAGA
TGTCAGGCTTTGCCCGGGGAGCCGAGCGGCAGCGGGGCTGTGAGTTTCAAATTAACCTTCCGCTTTGTTGCTGTGTAATGTGGATCCCCG
AAGGCCCCCCGCCCCGCCCGCCCCCCTTCCCCGGGCGGTGCGCGCTGCAAACTGCGAGTTGGGCTTCATTTACATAAAGCGATTCCGGGC
GGGCGGCGGCAGAGGAGGAGGCGGCGGCGGCGGGCAGGCCGGGGACCCGGACGCCAGCGCCGCGCCCCGTGGGTGAATCCCCGCCGCGTC
CCGGGGACCTCCCTCCGGGGACGGGCCGACCGCCAGCCCTGCCGCCACCATGAGCTCCCCTCCCCTGTCTCCGGGCCCCCTGCTCCTGAC
CAGAGCCACCTCCGAGTCCTGGGGCCAGCGGGAGGTGGGGAGCATGCCGCCTGGGGTGGGTGAGCTCGGGGCTCGGGTGCCACTGGAATT
TCCCGTTGTTGCGCATGGCGGCGCGGCCCCCGGACCTGCAAGTGCCGCCTCCCTCCGGAGGTGCGCGGAGGCTTGGTGTGCCAGGTCCGA
GCCTCCGTACTGGGTGCAATGAAAGCTCCACGCAGGCCTTACCATGGAAGGCTGTGACTCGCCCGTCGTCTCGGGGAAGGACAATGGGTG
CGGTATCCCTCAGCACCAGCAATGGACTGAACTCAACAGCACCCACCTCCCTGACAAACCCAGTAGCATGGAGCAGTCCACAGGCGAGAG
CCACGGGCCCTTGGACAGCCTGAGGGCCCCCTTCAATGAGCGCCTCGCGGAGAGCACCGCGTCGGCCGGGCCCCCCTCCGAGCCCGCCAG
CAAGGAGGTCACCTGCAACGAATGTTCGGCCTCCTTTGCCAGCCTCCAGACCTACATGGAGCACCACTGCCCCAGCGCGCGCCCCCCGCC
ACCCCTGAGAGAGGAGAGCGCCAGCGACACCGGTGAGGAGGGGGACGAGGAGAGTGACGTGGAGAACCTGGCCGGGGAGATCGTCTACCA
GCCGGACGGCTCCGCGTACATTGTGGAGAGCCTGAGCCAGCTGACCCAGGGCGGGGGCGCCTGTGGGAGTGGCAGTGGCAGTGGGCCTCT
CCCCTCGCTTTTCCTGAACTCTCTCCCTGGCGCGGGGGGCAAGCAAGGGGACCCTTCGTGTGCTGCACCCGTGTACCCGCAGATCATCAA
CACTTTCCACATAGCCTCATCCTTCGGGAAATGGTTTGAGGGCCCAGACCAGGCTTTCCCGAATACCTCAGCCCTGGCGGGGCTCAGCCC
CGTCCTGCACAGCTTCCGCGTGTTTGACGTGCGACACAAAAGCAACAAGGATTACCTGAACAGCGACGGTTCTGCCAAAAGCTCCTGCGT
ATCCAAAGATGTTCCCAACAATGTGGACCTGTCCAAATTCGATGGCTTTGTGCTCTATGGCAAGAGGAAGCCCATCCTGATGTGTTTCTT
GTGCAAACTCTCCTTTGGGTACGTCCGTTCGTTTGTGACCCACGCGGTGCATGACCATCGAATGACCCTGAGCGAAGACGAGCGGAAAAT
TCTTAGCAATAAGAACATCTCCGCTATCATCCAAGGGATCGGCAAAGACAAGGAACCCCTTGTAAGTTTTCTGGAACCAAAAAACAAAAA
CTTTCAACACCCTTTAGTTTCCACAGCTAACCTCATAGGCCCCGGACACAGTTTTTATGGTAAATTTAGTGGCATTCGAATGGAAGGGGA
GGAAGCTCTCCCAGCGGGCTCCGCCGCTGGCCCCGAGCAGCCCCAGGCTGGTCTCTTGACCCCCAGCACCCTGTTGAACCTTGGCGGGCT
CACCAGCTCGGTACTGAAGACCCCCATTACCTCAGTCCCCCTGGGGCCTCTGGCTTCCAGTCCTACCAAATCCTCAGAGGGCAAGGACTC
TGGGGCGGCAGAAGGAGAGAAGCAGGAAGTGGGCGACGGGGATTGCTTCTCTGAGAAGGTAGAGCCAGCCGAAGAGGAGGCGGAGGAGGA
AGAGGAGGAGGAAGAGGCGGAGGAGGAGGAGGAAGAAGAGGAGGAGGAAGAAGAGGAGGAGGAAGACGAGGGTTGCAAAGGACTCTTTCC
AAGCGAGTTGGATGAGGAACTGGAGGACAGGCCCCATGAGGAGCCTGGGGCCGCAGCAGGTAGTAGCAGCAAAAAGGACCTTGCTCTCTC
AAACCAAAGCATTTCTAACTCCCCCTTAATGCCTAACGTGCTCCAGACCCTGTCGAGGGGCACAGCTTCTACTAGTTCTAATTCTGCTTC
TTCCTTTGTTGTCTTTGATGGTGCGAACAGGAGGAATCGTTTAAGCTTTAACAGTGAGGGCGTCAGGGCCAATGTGGCAGAGGGCGGCAG
GAGGCTGGACTTCGCTGACGAAAGTGCCAATAAAGACAATGCCACAGCACCAGAACCAAATGAAAGCACAGAGGGTGACGATGGGGGCTT
CGTTCCCCATCACCAGCACGCTGGCTCCCTCTGCGAGCTTGGGGTTGGGGAGTGCCCCTCGGGGAGTGGCGTGGAGTGCCCCAAATGCGA
CACGGTCCTGGGCTCCTCCCGCTCGCTGGGCGGCCACATGACCATGATGCATTCTCGTAACTCGTGTAAGACACTCAAGTGCCCCAAGTG
CAACTGGCACTATAAGTACCAGCAGACCCTGGAGGCACACATGAAGGAGAAGCACCCGGAGCCGGGGGGCTCCTGTGTCTACTGCAAAAG
CGGGCAGCCCCACCCCCGGCTGGCACGAGGCGAGAGCTACACGTGTGGTTACAAGCCTTTCCGCTGCGAGGTGTGTAACTACTCCACAAC
TACCAAAGGCAACCTCAGTATTCATATGCAGTCTGACAAGCATCTCAACAACATGCAGAACCTGCAGAATGGAGGGGGGGAGCAGGTCTT
CAGCCACACTGCCGGGGCGGCGGCGGCGGCGGTGGCTGCGGCGGCGGCGGCAGCCAATATCAGTAGCTCCTGCGGGGCCCCCTCGCCGAC
CAAACCAAAAACCAAACCCACCTGGCGGTGCGAGGTGTGTGATTATGAGACCAACGTGGCCAGGAACCTCCGCATTCACATGACCAGTGA
GAAGCACATGCATAACATGATGTTACTGCAACAGAACATGACCCAGATCCAACACAACCGCCACCTGGGCCTCGGCAGCCTGCCCTCACC
CGCCGAGGCCGAGCTCTACCAATACTACCTGGCCCAGAACATGAACCTGCCCAACCTGAAGATGGACAGTGCTGCCTCGGACGCCCAGTT
CATGATGAGCGGATTCCAGCTGGATCCCGCCGGGCCCATGGCCGCCATGACGCCTGCTCTAGTGGGCGGTGAGATCCCCCTAGACATGCG
GCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGACCAACGACCCGTCGCTGAAGCTCTTCCA
GTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGTGGAGCGCAGCCTGTCGGAGGACGAGTG
GAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGCCAACTTCCAGCTGCACTGCAAGACAGA
CAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTGGAGGCTCAAGTGTGTGGCCATCGGCAA
CCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCTGCACACGGTCAACTCCAGGCACGAGGC
CAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTACTACCACTGCGTTCTGTGCAACTACTC
CACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAGCCTGCGAAAGCTGCAGCGGCTGCAGAA
GGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCACGGACCCAGAAGAAGCCATTGAAGATGT
TGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGCATCGTCCAGCCAAGCAGAGAAGGAGCT
GACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTCTTCGAAGCGACCAAAAACAGCTGAGGA
GATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCGGCTCCGGGTGCATGCCATGACGCAGCA
CTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCTCCAGCTGCACCTCACCCACCTCCACAG
CGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACCATCTGCAGTGTCTCCCTAAACTCAATA
GAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCAACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAA
ACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCA
CAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGAT
ATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTC
AAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGT
AAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTAT
TAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAG
ACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCA
AGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGT
GAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGG
CCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGG
TCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGT
TCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTG
TAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCT
AACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGA
GCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCA
GGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAA
GGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGT

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000315769_chr8_40438780_-_4060nt
AATTTAAAGTGGTCTCTATTCGAAGTCTCTGCTCTTTCACTTAAACCTTTACTCTAAGCTGTCCCCCTCCACTAATGCCCCCATTCTTTG
GAGATGCTCTTTTCCTAGTTAATTTAAACATTGCTGCGTTTGCTTAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAAGGGG
AAAATAATAAGAAAGAAAAGAGAAGGGGGGGAAGAAGAAAGGAAAAAAAAAATCTTAAAAAGATTCTTAGCCAGGTTCCTATTGTTGCTC
CTATGCATTCCACTTCTCGGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCTCGTGTGTGTGTCGTGTGTGTGTGTGT
GTGTGTTTTTAATACATGCATAAACTTTTGGAGCCTCTCTCCCTCTTCTAGGCTCTTCTCCCATCCTCTCTTCCTGCTCTCCTTGCCCTG
CTCATCACTTTCCCCTGTTTTTTTTTTTTTTTCCTCCCTTCCTCCCCTCTGCCTCCCTCCACCTCCCCCTTTTCTTTTTTGCTGAATCTT
ATTGATCCAGAAGGTGGCTAATTAGCCCTTCCCGTCGTGCCTGGGTAATGAAGCACATGCGCACTGAATTAATCACAGCCATTTTTTGCA
GGAAACTAATTAGCAGAATAAAGATCCAAAGACTTTTTTTTCTTTTCACTCATCAGCTCCCACTTCCAGCGCGTCCCCTCCGACCGCTGC
AGCCGCCACCGCCGCCGCCTCCTCCTCCTCCTCCTCCCGGCCGCAGCCGCCGCCGCCGCCTGCTTTGCATCCCAATTACAGCCTAGAGCC
GCTGCCGCCGCCGCCGCCGCTTCTCTTCCGTGGCCCCTGCCCGCTCCGGGGGCTGTAAACTCCCCGCCAACCATGCTGCTCGGCGGCAGC
GGCGGCGGCGGCTCCGGCTCCCCGGCTGCGGCCGCCTCCCGCCCCGGGCTCCGCCGAGCGCGCTCCAGCTCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCAGCAGCGCGTCCTCCGCCGCCGCCGACCCCCGCCAGCCGCCGCTGCTGCCTTGATGGGCTCCGCGGCCCGAGCGCCTC
TTTTCGGGATTAAAAGCGCCGCCAGCTCCCGCCGCCGCCGCCGTCGCCAGCAGCGCCGCTGCAGCCGCCGCCGCCGGAGAAGCAACCGCT
GGGCGGTGAGATCCCCCTAGACATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGAC
CAACGACCCGTCGCTGAAGCTCTTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGT
GGAGCGCAGCCTGTCGGAGGACGAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGC
CAACTTCCAGCTGCACTGCAAGACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTG
GAGGCTCAAGTGTGTGGCCATCGGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCT
GCACACGGTCAACTCCAGGCACGAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTA
CTACCACTGCGTTCTGTGCAACTACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAG
CCTGCGAAAGCTGCAGCGGCTGCAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCAC
GGACCCAGAAGAAGCCATTGAAGATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGC
ATCGTCCAGCCAAGCAGAGAAGGAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTC
TTCGAAGCGACCAAAAACAGCTGAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCG
GCTCCGGGTGCATGCCATGACGCAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCT
CCAGCTGCACCTCACCCACCTCCACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACC
ATCTGCAGTGTCTCCCTAAACTCAATAGAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCAACCTGAAGAATAAGTAGTGA
AAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGA
ACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCT
TTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATC
CTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATT
CTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGAC
ATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGA
GCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTC
TCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAA
AACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAA
ACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAA
GAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGA
AAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTT
TCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGG
ATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCA
AGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTT
CAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACG
AGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCT
CCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTTGTCAATTCCGCTGTAAAATAAGCATTGTCCGAGTAAAAACAGCAGC

>In-frame_ZFHX3_ENST00000397992_chr16_72845476_-_ZMAT4_ENST00000297737_chr8_40438780_-_4056nt
AATTTAAAGTGGTCTCTATTCGAAGTCTCTGCTCTTTCACTTAAACCTTTACTCTAAGCTGTCCCCCTCCACTAATGCCCCCATTCTTTG
GAGATGCTCTTTTCCTAGTTAATTTAAACATTGCTGCGTTTGCTTAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAAGGGG
AAAATAATAAGAAAGAAAAGAGAAGGGGGGGAAGAAGAAAGGAAAAAAAAAATCTTAAAAAGATTCTTAGCCAGGTTCCTATTGTTGCTC
CTATGCATTCCACTTCTCGGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCTCGTGTGTGTGTCGTGTGTGTGTGTGT
GTGTGTTTTTAATACATGCATAAACTTTTGGAGCCTCTCTCCCTCTTCTAGGCTCTTCTCCCATCCTCTCTTCCTGCTCTCCTTGCCCTG
CTCATCACTTTCCCCTGTTTTTTTTTTTTTTTCCTCCCTTCCTCCCCTCTGCCTCCCTCCACCTCCCCCTTTTCTTTTTTGCTGAATCTT
ATTGATCCAGAAGGTGGCTAATTAGCCCTTCCCGTCGTGCCTGGGTAATGAAGCACATGCGCACTGAATTAATCACAGCCATTTTTTGCA
GGAAACTAATTAGCAGAATAAAGATCCAAAGACTTTTTTTTCTTTTCACTCATCAGCTCCCACTTCCAGCGCGTCCCCTCCGACCGCTGC
AGCCGCCACCGCCGCCGCCTCCTCCTCCTCCTCCTCCCGGCCGCAGCCGCCGCCGCCGCCTGCTTTGCATCCCAATTACAGCCTAGAGCC
GCTGCCGCCGCCGCCGCCGCTTCTCTTCCGTGGCCCCTGCCCGCTCCGGGGGCTGTAAACTCCCCGCCAACCATGCTGCTCGGCGGCAGC
GGCGGCGGCGGCTCCGGCTCCCCGGCTGCGGCCGCCTCCCGCCCCGGGCTCCGCCGAGCGCGCTCCAGCTCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCAGCAGCGCGTCCTCCGCCGCCGCCGACCCCCGCCAGCCGCCGCTGCTGCCTTGATGGGCTCCGCGGCCCGAGCGCCTC
TTTTCGGGATTAAAAGCGCCGCCAGCTCCCGCCGCCGCCGCCGTCGCCAGCAGCGCCGCTGCAGCCGCCGCCGCCGGAGAAGCAACCGCT
GGGCGGTGAGATCCCCCTAGACATGCGGCTCGGGGGCGGGCAGCTGGTGTCAGAGGAGCTGATGAACCTGGGCGAGAGCTTCATCCAGAC
CAACGACCCGTCGCTGAAGCTCTTCCAGTGCGCCGTCTGCAACAAGTTCACGACGGACAACCTGGACATGCTGGGCCTGCACATGAACGT
GGAGCGCAGCCTGTCGGAGGACGAGTGGAAGGCGGTGATGGGGGACTCATACCAGTGCAAGCTCTGCCGCTACAACACCCAGCTCAAGGC
CAACTTCCAGCTGCACTGCAAGACAGACAAGCACGTGCAGAAGTACCAGCTGGTGGCCCACATCAAGGAGGGCGGCAAGGCCAACGAGTG
GAGGCTCAAGTGTGTGGCCATCGGCAACCCCGTGCACCTCAAGTGCAACGCCTGTGACTACTACACCAACAGCCTGGAGAAGCTGCGGCT
GCACACGGTCAACTCCAGGCACGAGGCCAGCCTGAAGTTGTACAAGCACCTGCAGCAGCATGAGAGTGGTGTAGAAGGTGAGAGCTGCTA
CTACCACTGCGTTCTGTGCAACTACTCCACCAAGGCCAAGCTCAACCTCATCCAGCATGTGCGCTCCATGAAGCACCAGCGAAGCGAGAG
CCTGCGAAAGCTGCAGCGGCTGCAGAAGGGCCTTCCAGAGGAGGACGAGGACCTGGGGCAGATCTTCACCATCCGCAGGTGCCCCTCCAC
GGACCCAGAAGAAGCCATTGAAGATGTTGAAGGACCCAGTGAAACAGCTGCTGATCCAGAGGAGCTTGCTAAGGACCAAGAGGGCGGAGC
ATCGTCCAGCCAAGCAGAGAAGGAGCTGACAGATTCTCCTGCAACCTCCAAACGCATCTCCTTCCCAGGTAGCTCAGAGTCTCCCCTCTC
TTCGAAGCGACCAAAAACAGCTGAGGAGATCAAACCGGAGCAGATGTACCAGTGTCCCTACTGCAAGTACAGTAATGCCGATGTCAACCG
GCTCCGGGTGCATGCCATGACGCAGCACTCGGTGCAACCCATGCTTCGCTGCCCCCTGTGCCAGGACATGCTCAACAACAAGATCCACCT
CCAGCTGCACCTCACCCACCTCCACAGCGTGGCACCTGACTGCGTGGAGAAGCTCATTATGACGGTCTGAGGCGCAATTACAGATGTACC
ATCTGCAGTGTCTCCCTAAACTCAATAGAACAGTATCATGCCCATCTGAAAGGATCTAAACACCAGACCAACCTGAAGAATAAGTAGTGA
AAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGA
ACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCT
TTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATC
CTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATT
CTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGAC
ATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGA
GCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTC
TCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAA
AACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAA
ACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAA
GAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGA
AAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTT
TCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGG
ATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCA
AGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTT
CAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACG
AGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCT
CCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTTGTCAATTCCGCTGTAAAATAAGCATTGTCCGAGTAAAAACAGCAGC


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FusionGenePPI for ZFHX3_ZMAT4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ZFHX3NINL, PRPF40A, TRIM25, ELAVL1, PIAS3, STAT3, KRT40, WRAP53, AURKAZMAT4APP, SRPK2, HECW2, CUL3, FAM26D, DSG4, HEPHL1, LYG2, S100A3, VSIG8, NEU2, TRIM29, LRRC15


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ZFHX3_ZMAT4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZFHX3_ZMAT4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneZFHX3C0004238Atrial Fibrillation3CTD_human
HgeneZFHX3C0033578Prostatic Neoplasms2CTD_human