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Fusion gene ID: 42569 |
FusionGeneSummary for ZC3H15_FAM171B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZC3H15_FAM171B | Fusion gene ID: 42569 | Hgene | Tgene | Gene symbol | ZC3H15 | FAM171B | Gene ID | 55854 | 165215 |
| Gene name | zinc finger CCCH-type containing 15 | family with sequence similarity 171 member B | |
| Synonyms | HT010|LEREPO4|MSTP012 | KIAA1946 | |
| Cytomap | 2q32.1 | 2q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger CCCH domain-containing protein 15DRG family-regulatory protein 1likely ortholog of mouse immediate early response erythropoietin 4 | protein FAM171B | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8WU90 | Q6P995 | |
| Ensembl transtripts involved in fusion gene | ENST00000337859, ENST00000544130, ENST00000468120, | ENST00000304698, | |
| Fusion gene scores | * DoF score | 4 X 2 X 4=32 | 3 X 4 X 3=36 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/36*10)=0.473931188332412 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ZC3H15 [Title/Abstract] AND FAM171B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AC-A6IW-01A | ZC3H15 | chr2 | 187351184 | + | FAM171B | chr2 | 187604955 | + |
| TCGA | LD | LUSC | TCGA-21-5783-01A | ZC3H15 | chr2 | 187366152 | + | FAM171B | chr2 | 187604955 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000337859 | ENST00000304698 | ZC3H15 | chr2 | 187351184 | + | FAM171B | chr2 | 187604955 | + |
| 5UTR-3CDS | ENST00000544130 | ENST00000304698 | ZC3H15 | chr2 | 187351184 | + | FAM171B | chr2 | 187604955 | + |
| intron-3CDS | ENST00000468120 | ENST00000304698 | ZC3H15 | chr2 | 187351184 | + | FAM171B | chr2 | 187604955 | + |
| In-frame | ENST00000337859 | ENST00000304698 | ZC3H15 | chr2 | 187366152 | + | FAM171B | chr2 | 187604955 | + |
| intron-3CDS | ENST00000544130 | ENST00000304698 | ZC3H15 | chr2 | 187366152 | + | FAM171B | chr2 | 187604955 | + |
| 3UTR-3CDS | ENST00000468120 | ENST00000304698 | ZC3H15 | chr2 | 187366152 | + | FAM171B | chr2 | 187604955 | + |
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FusionProtFeatures for ZC3H15_FAM171B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZC3H15 | FAM171B |
| Protects DRG1 from proteolytic degradation.{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ZC3H15 | chr2:187366152 | chr2:187604955 | ENST00000337859 | + | 4 | 10 | 61_86 | 147 | 427 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ZC3H15 | chr2:187366152 | chr2:187604955 | ENST00000337859 | + | 4 | 10 | 99_126 | 147 | 427 | Zinc finger | C3H1-type 1 |
| Tgene | >FAM171B | chr2:187366152 | chr2:187604955 | ENST00000304698 | + | 0 | 8 | 375_826 | 79 | 827 | Topological domain | Cytoplasmic |
| Tgene | >FAM171B | chr2:187366152 | chr2:187604955 | ENST00000304698 | + | 0 | 8 | 354_374 | 79 | 827 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ZC3H15 | chr2:187366152 | chr2:187604955 | ENST00000337859 | + | 4 | 10 | 218_285 | 147 | 427 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ZC3H15 | chr2:187366152 | chr2:187604955 | ENST00000337859 | + | 4 | 10 | 174_212 | 147 | 427 | Zinc finger | C3H1-type 2 |
| Tgene | FAM171B | chr2:187366152 | chr2:187604955 | ENST00000304698 | + | 0 | 8 | 43_58 | 79 | 827 | Compositional bias | Note=Gln-rich |
| Tgene | FAM171B | chr2:187366152 | chr2:187604955 | ENST00000304698 | + | 0 | 8 | 33_353 | 79 | 827 | Topological domain | Extracellular |
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FusionGeneSequence for ZC3H15_FAM171B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZC3H15_ENST00000337859_chr2_187366152_+_FAM171B_ENST00000304698_chr2_187604955_+_895aa MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVA AQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKT NSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKAL IKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAW TFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKC GTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSV NQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSATL PRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSELQG ISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLEDLD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZC3H15_ENST00000337859_chr2_187366152_+_FAM171B_ENST00000304698_chr2_187604955_+_2685nt ATGCCCCCCAAGAAACAGGCTCAGGCCGGGGGCAGCAAAAAGGCGGAGCAAAAAAAGAAGGAGAAGATTATCGAAGACAAAACTTTCGGT TTGAAGAATAAGAAAGGAGCAAAGCAACAGAAGTTTATCAAGGCTGTCACACATCAAGTTAAATTTGGTCAACAAAATCCACGTCAGGTA GCACAGAGTGAAGCTGAAAAGAAATTGAAGAAGGATGACAAGAAGAAAGAATTGCAGGAGCTAAATGAGCTGTTCAAACCTGTAGTTGCT GCTCAAAAAATAAGTAAAGGTGCAGATCCCAAGTCTGTAGTATGTGCATTCTTCAAGCAAGGACAGTGTACTAAAGGAGATAAGTGTAAG TTCTCCCATGACTTGACTCTGGAGAGAAAATGTGAAAAGCGAAGTGTTTACATTGATGCAAGAGATGAAGAACTTGAAAAAGTGTCTGTA TTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGTACCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGACA AATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAGTACCCTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGAT GGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGCCAATATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGCA AATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAATTAGCTGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTTA ATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCTATCTTACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCAT ACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTGAATTGACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGGA AAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTCTTCTACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTGG ACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGGGAATGGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGCA CCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTAGAGGTTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCAC ACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTGTCATTGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTGT GGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGGTCCTCAAGAGAGACCAGACAACTTCAACAACACACATAAATCATATC AGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGTTATTCAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACCA TCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTCGGGACGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGTC AATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGCCCAATGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATCT TCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAGGTAATGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTATG CATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACCTTTTCTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTTG CCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAGTAAATCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCAT TCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATACTTGAAGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCGA TACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACACTAAATGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGGA ATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCTCCCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGTT GCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGAGAACCCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAAT GAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCATCAAAAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGAC CTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGGACCCAGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCATG GAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTGAAGATTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZC3H15_ENST00000337859_chr2_187366152_+_FAM171B_ENST00000304698_chr2_187604955_+_6047nt TGGGCGCGCACGCGCAGCTCCGCTTCCGGGAGCCGCTCCTCGCTACCCACTATGCTCTGCGACATCGACCTGTCGCAAAGGCCGCGTTTG CGGGGCCAATGAGCGACTCGCTTTCCGTGCGGTGCGGCGAGTGAGGCCCCGGTCTTCCTCCTCGTCCTGCCGCAGGGCCAGAACCCCTGA CGGTATTCAGCTGCGCGTAAGTCTGGCCGGTGCCATCTGTCTCCGCAATGCCCCCCAAGAAACAGGCTCAGGCCGGGGGCAGCAAAAAGG CGGAGCAAAAAAAGAAGGAGAAGATTATCGAAGACAAAACTTTCGGTTTGAAGAATAAGAAAGGAGCAAAGCAACAGAAGTTTATCAAGG CTGTCACACATCAAGTTAAATTTGGTCAACAAAATCCACGTCAGGTAGCACAGAGTGAAGCTGAAAAGAAATTGAAGAAGGATGACAAGA AGAAAGAATTGCAGGAGCTAAATGAGCTGTTCAAACCTGTAGTTGCTGCTCAAAAAATAAGTAAAGGTGCAGATCCCAAGTCTGTAGTAT GTGCATTCTTCAAGCAAGGACAGTGTACTAAAGGAGATAAGTGTAAGTTCTCCCATGACTTGACTCTGGAGAGAAAATGTGAAAAGCGAA GTGTTTACATTGATGCAAGAGATGAAGAACTTGAAAAAGTGTCTGTATTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGT ACCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGACAAATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAG TACCCTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGATGGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGC CAATATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGCAAATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAAT TAGCTGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTTAATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCT ATCTTACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCATACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTG AATTGACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGGAAAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTC TTCTACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTGGACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGG GAATGGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGCACCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTA GAGGTTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCACACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTG TCATTGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTGTGGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGG TCCTCAAGAGAGACCAGACAACTTCAACAACACACATAAATCATATCAGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGT TATTCAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACCATCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTC GGGACGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGTCAATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGC CCAATGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATCTTCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAG GTAATGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTATGCATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACC TTTTCTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTTGCCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAG TAAATCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCATTCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATAC TTGAAGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCGATACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACAC TAAATGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGGAATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCT CCCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGTTGCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGA GAACCCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAATGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCA TCAAAAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGACCTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGG ACCCAGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCATGGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTG AAGATTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACCACCACTAGCCAAAAGAGATAGCAAGACTAACATCTGGAAGAAGC GAGAGGAACGCCCACTGATTCCCATAAATTAACTCCAATGGGGATTGTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGCTTCTTGTTGTA AATTGCAGTACGAACTTAAGAAAATGAGACTGAGCAATCTCATGGTTCTTGGACATGTCTCAAGCAGAGTAAATGGTAATTCAGTAATCA GAGAGAAAGATACCAAGGAATGCTTTTTCTGGCCTATTCATTTATTTTTGGGTGATGAATTTACAGTATCTAAGTTTTCAAAATGTAAAA TAGCTTCAAGATGTTAGTTATCTGAAAATGTTGCTCAGCCAGCCAGTTTGGCCTTGACTCTCTTAAGAATAACAGTGAAATATATACTCC TCAAGTTGCCTCCAAAAATGTTGCCTCTACCATGGTGACTACCCCATGGAACATTTAGAAACAAAACTGACTTCAGGCATCATATTATTT TAAATGTTACTATTACGTCTTCTTCTGCCTATACTTAAAAATAACTTGATAAATGACTTGGACTGATGTTACTCTGGAGTTATCACAAAG AAAATGTTGTTTGGTCTTTAAAGAGCATGTGTATTGTATCATCCCAAACGTAAATCCTACATTTATATAAGATGGGCAAGAAGCTACTTG GTCATTAGAGAGGGAGACACCAGCTCTTTGGTTGTTTTTGGATATAACTTTACAAAATAAGTAAGATGTTAATTTAGAAATTTGAGAAAT TAATGCTCTAATACTGAGTTTTTATTTAAAAATTATTTTTTCTTCCCCTCAACAATGAAGCAAGCTTAGCTGTCAAGGGAAACTTTTTAC AAATCTGAAAAAAACAATCTATGACTTTGGTTTAAGGCTCACTGATACTTTTAGGCTAAATTGGTTTTAATATATTTCTTCTATTCTAAA AACCTGAACTCAGTCACTTAAAGGCTATGAAATTTAAAAAAAAAGTCGATGTGAAAGTTTCTTTTGAACACTAAAATAAAATATGTGCAG ATAAAATATACATTGATTTGTTTTTCTTAAATGTTGATGAGAAGAAAAAGAGATGCCATTTTCCTGAGGCTCAAAAATACCTTCAGGATA GTTGTATATCCAGTTATTGATTTTCTTAAAAGATGTGTAAGGAAAACAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTTTCCCTAAGTCA CTTAAAGCCTTTGCAACTTCTTTTTTCAGTTTTGTAAGTAATATATCTATGTTCTTTTCATTATAGCAAGCATTCAATGTGAACAACTTT TTAATTAACTCTGAATTACCATTCATACATCCTAAAAATAAAAGCTCGTTATTCATTAAAATCAACTGATCCCATTTTTCTTAAAATTTC CCTGAAGGCAAATGTCTGAAGCACCTTTCCCTTGTGGGGGTAAAAATCCTAAATTGCTTTATTTTTCATTCCCTCCTATTCAACATGGGA GCAGCATAGAGACCCAAACCATGTAAACAAGTTCAGTGAACCAAAACAGCCACATTAGCTTCAGTAAAATTATAGCTAGATGTGCAATTT TTTCCTCCAACTTCTAACGTGTCAAATAACCTTCCTACTGTTCTGTGTTAACTGAAAGAACATAAAGACCCTAGGCAAATATTTGCTATA TATTACCCCAATCCATAGAAGAAATAATGTTTTGGGTAATACCTAGGCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAGTGATAAGGCTC ATAACAATTAATTAGAGAAGGCTTCTTATTGGTCTTACACAGAAAGATACATCAAAAGCAGCATGACTCAAAATGATTTGGAAAAGGTTA AAGTTAGTGCTCTGCTGAAGTGCCTTTGATATAGACTTGCATTATTAGAAGGATATAACATCTTTTTTAAGTGTGCATTTTCTTTCAGTT AACCAAATTAAACAGATGTGCAGTTTTATTAAAAATATAGACCTAGTGTTTCATGTTGGAACAATAAATATTGCATGTGAGTAGTATTTC TTGTTTTTTGAATACAGTATATATTGATAAATTGTTTATGTTGGAATGAAGTTAGAAACTATATAGCAAAACATTATATTTTAAGTGTTT ATTTTTCCCACCTTTAAATAAAAATGTTTCATCTCAGCTTGGTAATGAAATACACATATTGGTATAAGGGTATACCATTCAGGTATGCCA CTTATTTTATTCATTTTTGTGTAAGGGAAATGAGATGATGTATCCCAAGGGCTTTTCTAGAACTACTTGTTTGCTTTCAGAATAAAACCT TATTATTTTTTACACTGCACATGCTGTTCTCAATTGGTAATTATAGGCAATTTATCTTTTCTAATGATCAAAAGAGTGTGACTTCTCATT TGTGAGTAGTTCACAAATTTCCTGTTAAAAAGCTGAAACCATCTACTTTTTCTTAACCCAAGTGATAATAAACAATATTCACAACTTTCT TAAATTTTTAAATTGAAAACCAAGGTTTTTTCAAATATAAACCTAGATGATTTTGGTCACAAATTGTTAACATTTGTCGATCCTTTGTAT ATACTTTGGATATATATTAAAGGCAAAACTATCTCTTGACTAACTGATGGATTCATTTACTAAAGCACAGCTGTATGTATTTTTGAATAC ATATTATGATCTTGAGACTTTATAAATCAATTTTTATGACTTTATGCAGTTGTATAGGGATTATGCCCTTTCAGTTCTATAGGGATTATG CCCTTTTATAATACATAATATACCACAGAGATTACAAATGTTGAGGAATGAAAGCACTTCTTTGCTTTGGCAATCATTTTCAGACCACTA TGTGTTTGAATCCTCTGGTATCAATACGTATTATAGGGTTTTAGAGATCTGTGGGTCAAATGATGTCCCTCAAAACTTCCTAAAAAGGTG AAGCTCAAAGTCACACATTCTTATAAGGCGCATGAGTTTCTCATTTTCCCATGTACGAGCATTGTAAAGGAATTCAGCTGTATTAATTTC TATTTCAGATCTAGAATTGACATTTTGCCTTCTTGTTTCCAGGTGTTTCTATTTTTTGTATTCTTTCAGAGAAATCTCATATTTCGGTGT ATTTATTGCTGTTACTACTATATTTACTGCTGAAAACTGTAACAACCTGAAGATTTGTAAAATGTTAAACATAGTTCATTAAAAATAATA |
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FusionGenePPI for ZC3H15_FAM171B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZC3H15 | TNNT1, C8orf33, DRG1, ISG15, THOC1, THOC3, THOC5, THOC2, THOC6, THOC7, WASF1, UTRN, PPIP5K1, TSSK2, ZCCHC8, PPIP5K2, CSNK2A1, PARK2, PHKG2, STAU1, TRAF2, RNF2, ABCF2, FAF1, GINS3, HMGN5, WDR74, NTRK1, KRAS, MED4, CC2D2A, CEP44, DCTN1, CEP19, CETN2, XPO1, TM9SF4, MRPL50, CDH1, NCL, MTF1, BRD1 | FAM171B | MPP3, CAMK2D, TMEM17, CDH1, CTDSPL, FAM171A1, FAM171A2, C4A, FGFR2, BMPR1A, STX6, PHKG2, MFAP3, MIB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZC3H15_FAM171B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZC3H15_FAM171B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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