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Fusion gene ID: 4231 |
FusionGeneSummary for BMP2K_SLC25A31 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BMP2K_SLC25A31 | Fusion gene ID: 4231 | Hgene | Tgene | Gene symbol | BMP2K | SLC25A31 | Gene ID | 55589 | 83447 |
| Gene name | BMP2 inducible kinase | solute carrier family 25 member 31 | |
| Synonyms | BIKE|HRIHFB2017 | AAC4|ANT 4|ANT4|SFEC35kDa | |
| Cytomap | 4q21.21 | 4q28.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | BMP-2-inducible protein kinase | ADP/ATP translocase 4ADP,ATP carrier protein 4adenine nucleotide translocase 4adenine nucleotide translocator 4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31sperm flagellar energy carrier protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NSY1 | Q9H0C2 | |
| Ensembl transtripts involved in fusion gene | ENST00000335016, ENST00000502871, | ENST00000281154, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 3 X 2 X 3=18 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: BMP2K [Title/Abstract] AND SLC25A31 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-55-1592-01A | BMP2K | chr4 | 79786874 | + | SLC25A31 | chr4 | 128694541 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000335016 | ENST00000281154 | BMP2K | chr4 | 79786874 | + | SLC25A31 | chr4 | 128694541 | + |
| In-frame | ENST00000502871 | ENST00000281154 | BMP2K | chr4 | 79786874 | + | SLC25A31 | chr4 | 128694541 | + |
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FusionProtFeatures for BMP2K_SLC25A31 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BMP2K | SLC25A31 |
| May be involved in osteoblast differentiation. | Catalyzes the exchange of cytoplasmic ADP withmitochondrial ATP across the mitochondrial inner membrane. Mayserve to mediate energy generating and energy consuming processesin the distal flagellum, possibly as a nucleotide shuttle betweenflagellar glycolysis, protein phosphorylation and mechanisms ofmotility. {ECO:0000269|PubMed:17137571}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000335016 | + | 10 | 16 | 12_40 | 410 | 1162 | Compositional bias | Note=Gly-rich |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000502871 | + | 10 | 14 | 12_40 | 410 | 663 | Compositional bias | Note=Gly-rich |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000335016 | + | 10 | 16 | 51_316 | 410 | 1162 | Domain | Protein kinase |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000502871 | + | 10 | 14 | 51_316 | 410 | 663 | Domain | Protein kinase |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000335016 | + | 10 | 16 | 57_65 | 410 | 1162 | Nucleotide binding | ATP |
| Hgene | BMP2K | chr4:79786874 | chr4:128694541 | ENST00000502871 | + | 10 | 14 | 57_65 | 410 | 663 | Nucleotide binding | ATP |
| Tgene | >SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 284_301 | 253 | 316 | Transmembrane | Helical%3B Name%3D6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BMP2K | chr4:79786874 | chr4:128694541 | ENST00000335016 | + | 10 | 16 | 425_559 | 410 | 1162 | Compositional bias | Note=Gln/His-rich |
| Hgene | >BMP2K | chr4:79786874 | chr4:128694541 | ENST00000502871 | + | 10 | 14 | 425_559 | 410 | 663 | Compositional bias | Note=Gln/His-rich |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 247_252 | 253 | 316 | Motif | Nucleotide carrier signature motif |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 123_213 | 253 | 316 | Repeat | Note=Solcar 2 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 18_110 | 253 | 316 | Repeat | Note=Solcar 1 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 220_307 | 253 | 316 | Repeat | Note=Solcar 3 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 122_142 | 253 | 316 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 191_211 | 253 | 316 | Transmembrane | Helical%3B Name%3D4 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 20_49 | 253 | 316 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 223_243 | 253 | 316 | Transmembrane | Helical%3B Name%3D5 |
| Tgene | SLC25A31 | chr4:79786874 | chr4:128694541 | ENST00000281154 | + | 4 | 6 | 87_111 | 253 | 316 | Transmembrane | Helical%3B Name%3D2 |
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FusionGeneSequence for BMP2K_SLC25A31 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BMP2K_ENST00000335016_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_473aa MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLN VCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRD LKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQ VAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDT IGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKEWXGXTAIXRNLRLLCEDIPTXRNQFLFSWRLLQCSSRYR >In-frame_BMP2K_ENST00000502871_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_473aa MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLN VCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRD LKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQ VAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDT IGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKEWXGXTAIXRNLRLLCEDIPTXRNQFLFSWRLLQCSSRYR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BMP2K_ENST00000335016_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_1420nt ATGAAGAAGTTCTCTCGGATGCCCAAGTCGGAGGGCGGCAGCGGCGGCGGAGCGGCGGGTGGCGGGGCTGGCGGGGCCGGGGCCGGGGCC GGCTGCGGCTCCGGCGGCTCGTCCGTGGGGGTCCGGGTGTTCGCGGTCGGCCGCCACCAGGTCACCCTGGAAGAGTCGCTGGCCGAAGGT GGATTCTCCACAGTTTTCCTCGTGCGTACTCACGGTGGAATCCGATGTGCATTGAAGCGAATGTATGTCAATAACATGCCAGACCTCAAT GTTTGTAAAAGGGAAATTACAATTATGAAAGAGCTATCTGGTCACAAAAATATTGTGGGCTATTTGGACTGTGCTGTTAATTCAATTAGT GATAATGTATGGGAAGTCCTTATCTTAATGGAATATTGTCGAGCTGGACAGGTAGTGAATCAAATGAATAAGAAGCTACAGACGGGTTTT ACAGAACCAGAAGTGTTACAGATATTCTGTGATACCTGTGAAGCTGTTGCAAGGTTGCATCAGTGTAAGACTCCAATAATTCACCGGGAT CTGAAGGTAGAAAATATTTTGTTGAATGATGGTGGGAACTATGTACTTTGTGACTTTGGCAGTGCCACTAATAAATTTCTTAATCCTCAA AAAGATGGAGTTAATGTAGTAGAAGAAGAAATTAAAAAGTATACAACTCTGTCATACAGAGCCCCTGAAATGATCAACCTTTATGGAGGG AAACCCATCACCACCAAGGCTGATATCTGGGCACTGGGATGTCTACTCTATAAACTTTGTTTCTTCACTCTTCCTTTTGGTGAGAGTCAG GTTGCTATCTGTGATGGCAACTTCACCATCCCAGACAATTCTCGTTACTCCCGTAACATACATTGCTTAATAAGGTTCATGCTTGAACCA GATCCGGAACATAGACCTGATATATTTCAAGTGTCATATTTTGCATTTAAATTTGCCAAAAAGGATTGTCCAGTCTCCAACATCAATAAT TCTTCTATTCCTTCAGCTCTTCCTGAACCGATGACTGCTAGTGAAGCAGCTGCTAGGAAAAGCCAAATAAAAGCCAGAATAACAGATACC ATTGGACCAACAGAAACCTCAATTGCACCAAGACAAAGACCAAAGGCCAACTCTGCTACTACTGCCACTCCCAGTGTGCTGACCATTCAA AGTTCAGCAACACCTGTTAAAGTCCTTGCTCCTGGTGAATTCGGTAACCATAGACCAAAAGAGTGGTGAGGCTAAACGGCAATATAAAGG AACCTTAGACTGCTTTGTGAAGATATACCAACATGAAGGAATCAGTTCCTTTTTTCGTGGCGCCTTCTCCAATGTTCTTCGCGGTACAGG >In-frame_BMP2K_ENST00000502871_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_1420nt ATGAAGAAGTTCTCTCGGATGCCCAAGTCGGAGGGCGGCAGCGGCGGCGGAGCGGCGGGTGGCGGGGCTGGCGGGGCCGGGGCCGGGGCC GGCTGCGGCTCCGGCGGCTCGTCCGTGGGGGTCCGGGTGTTCGCGGTCGGCCGCCACCAGGTCACCCTGGAAGAGTCGCTGGCCGAAGGT GGATTCTCCACAGTTTTCCTCGTGCGTACTCACGGTGGAATCCGATGTGCATTGAAGCGAATGTATGTCAATAACATGCCAGACCTCAAT GTTTGTAAAAGGGAAATTACAATTATGAAAGAGCTATCTGGTCACAAAAATATTGTGGGCTATTTGGACTGTGCTGTTAATTCAATTAGT GATAATGTATGGGAAGTCCTTATCTTAATGGAATATTGTCGAGCTGGACAGGTAGTGAATCAAATGAATAAGAAGCTACAGACGGGTTTT ACAGAACCAGAAGTGTTACAGATATTCTGTGATACCTGTGAAGCTGTTGCAAGGTTGCATCAGTGTAAGACTCCAATAATTCACCGGGAT CTGAAGGTAGAAAATATTTTGTTGAATGATGGTGGGAACTATGTACTTTGTGACTTTGGCAGTGCCACTAATAAATTTCTTAATCCTCAA AAAGATGGAGTTAATGTAGTAGAAGAAGAAATTAAAAAGTATACAACTCTGTCATACAGAGCCCCTGAAATGATCAACCTTTATGGAGGG AAACCCATCACCACCAAGGCTGATATCTGGGCACTGGGATGTCTACTCTATAAACTTTGTTTCTTCACTCTTCCTTTTGGTGAGAGTCAG GTTGCTATCTGTGATGGCAACTTCACCATCCCAGACAATTCTCGTTACTCCCGTAACATACATTGCTTAATAAGGTTCATGCTTGAACCA GATCCGGAACATAGACCTGATATATTTCAAGTGTCATATTTTGCATTTAAATTTGCCAAAAAGGATTGTCCAGTCTCCAACATCAATAAT TCTTCTATTCCTTCAGCTCTTCCTGAACCGATGACTGCTAGTGAAGCAGCTGCTAGGAAAAGCCAAATAAAAGCCAGAATAACAGATACC ATTGGACCAACAGAAACCTCAATTGCACCAAGACAAAGACCAAAGGCCAACTCTGCTACTACTGCCACTCCCAGTGTGCTGACCATTCAA AGTTCAGCAACACCTGTTAAAGTCCTTGCTCCTGGTGAATTCGGTAACCATAGACCAAAAGAGTGGTGAGGCTAAACGGCAATATAAAGG AACCTTAGACTGCTTTGTGAAGATATACCAACATGAAGGAATCAGTTCCTTTTTTCGTGGCGCCTTCTCCAATGTTCTTCGCGGTACAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BMP2K_ENST00000335016_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_2305nt CGGGGCCCAGGCTGTGCGCTTGGGGAGCGCGGAATGTGAGGCTTGGCGGGCCGCAGCACGCTCGGACGGGCCAGGGGCGGCGACCCCTCG CGGACGCCCGGCTGCGCGCCGGGCCGGGGACTTGCCCTTGCACGCTCCCTGCGCCCTCCAGCTCGCCGGCGGGACCATGAAGAAGTTCTC TCGGATGCCCAAGTCGGAGGGCGGCAGCGGCGGCGGAGCGGCGGGTGGCGGGGCTGGCGGGGCCGGGGCCGGGGCCGGCTGCGGCTCCGG CGGCTCGTCCGTGGGGGTCCGGGTGTTCGCGGTCGGCCGCCACCAGGTCACCCTGGAAGAGTCGCTGGCCGAAGGTGGATTCTCCACAGT TTTCCTCGTGCGTACTCACGGTGGAATCCGATGTGCATTGAAGCGAATGTATGTCAATAACATGCCAGACCTCAATGTTTGTAAAAGGGA AATTACAATTATGAAAGAGCTATCTGGTCACAAAAATATTGTGGGCTATTTGGACTGTGCTGTTAATTCAATTAGTGATAATGTATGGGA AGTCCTTATCTTAATGGAATATTGTCGAGCTGGACAGGTAGTGAATCAAATGAATAAGAAGCTACAGACGGGTTTTACAGAACCAGAAGT GTTACAGATATTCTGTGATACCTGTGAAGCTGTTGCAAGGTTGCATCAGTGTAAGACTCCAATAATTCACCGGGATCTGAAGGTAGAAAA TATTTTGTTGAATGATGGTGGGAACTATGTACTTTGTGACTTTGGCAGTGCCACTAATAAATTTCTTAATCCTCAAAAAGATGGAGTTAA TGTAGTAGAAGAAGAAATTAAAAAGTATACAACTCTGTCATACAGAGCCCCTGAAATGATCAACCTTTATGGAGGGAAACCCATCACCAC CAAGGCTGATATCTGGGCACTGGGATGTCTACTCTATAAACTTTGTTTCTTCACTCTTCCTTTTGGTGAGAGTCAGGTTGCTATCTGTGA TGGCAACTTCACCATCCCAGACAATTCTCGTTACTCCCGTAACATACATTGCTTAATAAGGTTCATGCTTGAACCAGATCCGGAACATAG ACCTGATATATTTCAAGTGTCATATTTTGCATTTAAATTTGCCAAAAAGGATTGTCCAGTCTCCAACATCAATAATTCTTCTATTCCTTC AGCTCTTCCTGAACCGATGACTGCTAGTGAAGCAGCTGCTAGGAAAAGCCAAATAAAAGCCAGAATAACAGATACCATTGGACCAACAGA AACCTCAATTGCACCAAGACAAAGACCAAAGGCCAACTCTGCTACTACTGCCACTCCCAGTGTGCTGACCATTCAAAGTTCAGCAACACC TGTTAAAGTCCTTGCTCCTGGTGAATTCGGTAACCATAGACCAAAAGAGTGGTGAGGCTAAACGGCAATATAAAGGAACCTTAGACTGCT TTGTGAAGATATACCAACATGAAGGAATCAGTTCCTTTTTTCGTGGCGCCTTCTCCAATGTTCTTCGCGGTACAGGGGGTGCTTTGGTGT TGGTATTATATGATAAAATTAAAGAATTCTTTCATATTGATATTGGTGGTAGGTAATCGGGAGAGTAAATTAAGAAATACATGGATTTAA CTTGTTAAACATACAAATTACATAGCTGCCATTTGCATACATTTTGATAGTGTTATTGTCTGTATTTTGTTAAAGTGCTAGTTCTGCAAT AAAGCATACATTTTTTCAAGAATTTAAATACTAAAAATCAGATAAATGTGGATTTTCCTCCCACTTAGACTCAAACACATTTTAGTGTGA TATTTCATTTATTATAGGTAGTATATTTTAATTTGTTAGTTTAAAATTCTTTTTATGATTAAAAATTAATCATATAATCCTAGATTAATG CTGAAATCTAGGAAATGAAAGTAGCGTCTTTTAAATTGCTATTCATTTAATATACCTGTTTTCCCATCTTTTGAAGTCATATGGTATGAC ATATTTCTTAAAAGCTTATCAATAGATGTCATCATATGTGTAGGCAGAAATAAGCTTTGTTCTATATCTCTTCTAAGACAGTTGTTATTA CTGTGTATAATATTTACAGTATCAGCCTTTGATTATAGATGTGATCATTTAAAATTTGATAATGACTTTAGTGACATTATAAAACTGAAA CTGGAAAATAAAATGGCTTATCTGCTGATGTTTATCTTTAAAATAAATAAAATCTTGCTAGTGTGAATATATCTTAGAACAAAAGGTATC >In-frame_BMP2K_ENST00000502871_chr4_79786874_+_SLC25A31_ENST00000281154_chr4_128694541_+_2305nt CGGGGCCCAGGCTGTGCGCTTGGGGAGCGCGGAATGTGAGGCTTGGCGGGCCGCAGCACGCTCGGACGGGCCAGGGGCGGCGACCCCTCG CGGACGCCCGGCTGCGCGCCGGGCCGGGGACTTGCCCTTGCACGCTCCCTGCGCCCTCCAGCTCGCCGGCGGGACCATGAAGAAGTTCTC TCGGATGCCCAAGTCGGAGGGCGGCAGCGGCGGCGGAGCGGCGGGTGGCGGGGCTGGCGGGGCCGGGGCCGGGGCCGGCTGCGGCTCCGG CGGCTCGTCCGTGGGGGTCCGGGTGTTCGCGGTCGGCCGCCACCAGGTCACCCTGGAAGAGTCGCTGGCCGAAGGTGGATTCTCCACAGT TTTCCTCGTGCGTACTCACGGTGGAATCCGATGTGCATTGAAGCGAATGTATGTCAATAACATGCCAGACCTCAATGTTTGTAAAAGGGA AATTACAATTATGAAAGAGCTATCTGGTCACAAAAATATTGTGGGCTATTTGGACTGTGCTGTTAATTCAATTAGTGATAATGTATGGGA AGTCCTTATCTTAATGGAATATTGTCGAGCTGGACAGGTAGTGAATCAAATGAATAAGAAGCTACAGACGGGTTTTACAGAACCAGAAGT GTTACAGATATTCTGTGATACCTGTGAAGCTGTTGCAAGGTTGCATCAGTGTAAGACTCCAATAATTCACCGGGATCTGAAGGTAGAAAA TATTTTGTTGAATGATGGTGGGAACTATGTACTTTGTGACTTTGGCAGTGCCACTAATAAATTTCTTAATCCTCAAAAAGATGGAGTTAA TGTAGTAGAAGAAGAAATTAAAAAGTATACAACTCTGTCATACAGAGCCCCTGAAATGATCAACCTTTATGGAGGGAAACCCATCACCAC CAAGGCTGATATCTGGGCACTGGGATGTCTACTCTATAAACTTTGTTTCTTCACTCTTCCTTTTGGTGAGAGTCAGGTTGCTATCTGTGA TGGCAACTTCACCATCCCAGACAATTCTCGTTACTCCCGTAACATACATTGCTTAATAAGGTTCATGCTTGAACCAGATCCGGAACATAG ACCTGATATATTTCAAGTGTCATATTTTGCATTTAAATTTGCCAAAAAGGATTGTCCAGTCTCCAACATCAATAATTCTTCTATTCCTTC AGCTCTTCCTGAACCGATGACTGCTAGTGAAGCAGCTGCTAGGAAAAGCCAAATAAAAGCCAGAATAACAGATACCATTGGACCAACAGA AACCTCAATTGCACCAAGACAAAGACCAAAGGCCAACTCTGCTACTACTGCCACTCCCAGTGTGCTGACCATTCAAAGTTCAGCAACACC TGTTAAAGTCCTTGCTCCTGGTGAATTCGGTAACCATAGACCAAAAGAGTGGTGAGGCTAAACGGCAATATAAAGGAACCTTAGACTGCT TTGTGAAGATATACCAACATGAAGGAATCAGTTCCTTTTTTCGTGGCGCCTTCTCCAATGTTCTTCGCGGTACAGGGGGTGCTTTGGTGT TGGTATTATATGATAAAATTAAAGAATTCTTTCATATTGATATTGGTGGTAGGTAATCGGGAGAGTAAATTAAGAAATACATGGATTTAA CTTGTTAAACATACAAATTACATAGCTGCCATTTGCATACATTTTGATAGTGTTATTGTCTGTATTTTGTTAAAGTGCTAGTTCTGCAAT AAAGCATACATTTTTTCAAGAATTTAAATACTAAAAATCAGATAAATGTGGATTTTCCTCCCACTTAGACTCAAACACATTTTAGTGTGA TATTTCATTTATTATAGGTAGTATATTTTAATTTGTTAGTTTAAAATTCTTTTTATGATTAAAAATTAATCATATAATCCTAGATTAATG CTGAAATCTAGGAAATGAAAGTAGCGTCTTTTAAATTGCTATTCATTTAATATACCTGTTTTCCCATCTTTTGAAGTCATATGGTATGAC ATATTTCTTAAAAGCTTATCAATAGATGTCATCATATGTGTAGGCAGAAATAAGCTTTGTTCTATATCTCTTCTAAGACAGTTGTTATTA CTGTGTATAATATTTACAGTATCAGCCTTTGATTATAGATGTGATCATTTAAAATTTGATAATGACTTTAGTGACATTATAAAACTGAAA CTGGAAAATAAAATGGCTTATCTGCTGATGTTTATCTTTAAAATAAATAAAATCTTGCTAGTGTGAATATATCTTAGAACAAAAGGTATC |
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FusionGenePPI for BMP2K_SLC25A31 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BMP2K | KDM5B, TERF1, TERF2, ABL1, EPS15, AP2M1, FN1, SLC25A41, LIMS1, XPO1, CAPZA2, CDK2, CLTB, CLTC, DBN1, FLNA, GAK, GBA, MYH9, PPP1CB, PICALM, IQGAP1, PDLIM7, SEC16A, SYNPO, LIMA1, GTSE1, ANLN, MYO19, MYO18A, AP2S1, CLINT1, REPS1, STAMBP, STAMBPL1, RALBP1, INTS4, RUNDC3A | SLC25A31 | PPP4C, ZDHHC17 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BMP2K_SLC25A31 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BMP2K_SLC25A31 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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