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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 42253

FusionGeneSummary for XXYLT1_TPRG1

check button Fusion gene summary
Fusion gene informationFusion gene name: XXYLT1_TPRG1
Fusion gene ID: 42253
HgeneTgene
Gene symbol

XXYLT1

TPRG1

Gene ID

152002

285386

Gene namexyloside xylosyltransferase 1tumor protein p63 regulated 1
SynonymsC3orf21FAM79B
Cytomap

3q29

3q28

Type of geneprotein-codingprotein-coding
Descriptionxyloside xylosyltransferase 1UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferasetumor protein p63-regulated gene 1 proteinfamily with sequence similarity 79, member B
Modification date2018051920180403
UniProtAcc

Q8NBI6

Q6ZUI0

Ensembl transtripts involved in fusion geneENST00000310380, ENST00000437101, 
ENST00000429994, ENST00000355729, 
ENST00000460582, ENST00000356740, 
ENST00000433971, ENST00000345063, 
ENST00000488841, 
Fusion gene scores* DoF score8 X 5 X 6=24012 X 6 X 6=432
# samples 913
** MAII scorelog2(9/240*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(13/432*10)=-1.73251968913501
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: XXYLT1 [Title/Abstract] AND TPRG1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneXXYLT1

GO:0016266

O-glycan processing

8982869|22117070


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUSCTCGA-22-4591-01AXXYLT1chr3

194877178

-TPRG1chr3

189028175

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000310380ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000310380ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000310380ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
Frame-shitENST00000437101ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
Frame-shitENST00000437101ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000437101ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000429994ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000429994ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000429994ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000355729ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
In-frameENST00000355729ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
5CDS-intronENST00000355729ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000460582ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000460582ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-intronENST00000460582ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000356740ENST00000433971XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-3CDSENST00000356740ENST00000345063XXYLT1chr3

194877178

-TPRG1chr3

189028175

+
intron-intronENST00000356740ENST00000488841XXYLT1chr3

194877178

-TPRG1chr3

189028175

+

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FusionProtFeatures for XXYLT1_TPRG1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
XXYLT1

Q8NBI6

TPRG1

Q6ZUI0

Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats inthe extracellular domain of target proteins by catalyzing theaddition of the second xylose (PubMed:22117070, PubMed:8982869).Known targets include Notch proteins and coagulation factors, suchas F9 (PubMed:22117070, PubMed:8982869).{ECO:0000269|PubMed:22117070, ECO:0000269|PubMed:8982869}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-34104_106261394RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-341_23261394Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-231_2358191Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-451_2358191Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-3424_44261394TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-2324_4458191TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-4524_4458191TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-23104_10658191RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-12104_1060188RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-45104_10658191RegionUDP-alpha-D-xylose binding
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-3445_393261394Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-2345_39358191Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-121_230188Topological domainCytoplasmic
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-1245_3930188Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-4545_39358191Topological domainLumenal
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-1224_440188TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneTPRG1chr3:194877178chr3:189028175ENST00000345063+3668_240159276DomainhSac2
TgeneTPRG1chr3:194877178chr3:189028175ENST00000433971+81168_240159276DomainhSac2


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FusionGeneSequence for XXYLT1_TPRG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_378aa
MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLE
GGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDK
LFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRI
YWGSPEEQSLLSRWNPWSTEVPTATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQNAHKNSTGSGRGKKLMVLTEPILIETYTGLMSFI

>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_378aa
MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLE
GGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDK
LFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRI
YWGSPEEQSLLSRWNPWSTEVPTATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQNAHKNSTGSGRGKKLMVLTEPILIETYTGLMSFI

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_232aa
MVRCVPSAVIVCFLRPPQPGRTVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIR
ELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPTATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQ

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_232aa
MVRCVPSAVIVCFLRPPQPGRTVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIR
ELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPTATFTEHPMKYTSEKFLEICKLSGFMSKLVPAIQ

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_175aa
MWPPRCKDPGRQSAEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPT

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_175aa
MWPPRCKDPGRQSAEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRRQGEGLRIYWGSPEEQSLLSRWNPWSTEVPT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_1134nt
ATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTACTGCGCCCTGCTGCTGGCC
GCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAGGCTGAAGGAGGCCCGCGCC
GGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGCGAAGGCCAAGAGCTTGGAG
GGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCTGCAGGCCAAGGCCCGCGTC
GCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGAGGAGGCCAGCCGCGAGGTG
GCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGTTGCTGTGCTGACGGATAAG
CTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGGTCGCC
ATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGTTTGAG
GAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTAGGATC
TACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGCATCCT
ATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCCACAAG
AATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCATTCATT

>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_1134nt
ATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTACTGCGCCCTGCTGCTGGCC
GCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAGGCTGAAGGAGGCCCGCGCC
GGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGCGAAGGCCAAGAGCTTGGAG
GGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCTGCAGGCCAAGGCCCGCGTC
GCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGAGGAGGCCAGCCGCGAGGTG
GCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGTTGCTGTGCTGACGGATAAG
CTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGGTCGCC
ATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGTTTGAG
GAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTAGGATC
TACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGCATCCT
ATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCCACAAG
AATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCATTCATT

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_696nt
ATGGTGAGATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTG
CTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTC
CTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGG
GAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAA
GGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTC
ACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAG
AATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTG

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_696nt
ATGGTGAGATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTG
CTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTC
CTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGG
GAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAA
GGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTC
ACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAG
AATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTG

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_525nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_525nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_1484nt
CCCCTTTCATGGCCGCCGCCTGGCGCCGGGGCTAAGTGGCCGCCGGCGTCCGGGTACCCGAGGGCTCTCCCGCGTTGCTGGCACCGCTGG
CGCCGCGGTCTCGTAGCGCATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTA
CTGCGCCCTGCTGCTGGCCGCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAG
GCTGAAGGAGGCCCGCGCCGGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGC
GAAGGCCAAGAGCTTGGAGGGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCT
GCAGGCCAAGGCCCGCGTCGCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGA
GGAGGCCAGCCGCGAGGTGGCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGT
TGCTGTGCTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCAT
CTTCTTCCTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAA
CATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACA
AGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGC
TACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGC
TATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACAC
AGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCA
TAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGA
CGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAA

>In-frame_XXYLT1_ENST00000310380_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_5727nt
CCCCTTTCATGGCCGCCGCCTGGCGCCGGGGCTAAGTGGCCGCCGGCGTCCGGGTACCCGAGGGCTCTCCCGCGTTGCTGGCACCGCTGG
CGCCGCGGTCTCGTAGCGCATGGGCCTCCTCCGAGGCGGGCTCCCATGCGCTCGGGCCATGGCGCGCCTGGGCGCTGTGCGCTCCCACTA
CTGCGCCCTGCTGCTGGCCGCGGCGCTGGCCGTCTGCGCCTTCTACTACCTCGGCTCAGGCCGGGAGACCTTCTCCAGCGCCACCAAGAG
GCTGAAGGAGGCCCGCGCCGGGGCTCCCGCCGCGCCCTCGCCGCCCGCGCTGGAGCTAGCGCGGGGCTCCGTGGCGCCAGCCCCCGGCGC
GAAGGCCAAGAGCTTGGAGGGCGGCGGTGCCGGGCCGGTGGACTACCACCTGCTGATGATGTTCACCAAGGCGGAGCACAATGCCGCGCT
GCAGGCCAAGGCCCGCGTCGCGCTGCGCTCACTGCTGCGCCTCGCCAAGTTCGAGGCGCACGAGGTGCTTAACCTTCACTTCGTGAGCGA
GGAGGCCAGCCGCGAGGTGGCCAAGGGCCTGCTGCGGGAGCTCCTGCCGCCCGCCGCTGGCTTCAAGTGCAAGGTCATCTTCCACGATGT
TGCTGTGCTGACGGATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCAT
CTTCTTCCTCTCGGTCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAA
CATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACA
AGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGC
TACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGC
TATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACAC
AGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCA
TAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGA
CGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAA
TCAAATTTTCTTAAAACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAGAA
GACTCTAAGTCCTGTTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTGAT
TTATTCTCTCATTGGGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAATAT
TTATTCCAAGACTCAGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAATCC
TGTGGTATTTATATGGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATGAT
CACATCTCTATACGGCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCCTC
CTTTCCATTCTTATAGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTACTC
CAAGGCTGACTGTTTCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAACA
GACCTTTTTCTTCTAAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAGAA
TGCCACAGGCATCTTTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCAAA
AACACTGTCTTAACACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAACCC
AGGAAATTATCTCATATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAAAA
GCTTTGAATGTTGACTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTAAG
TTGAAATTCCAGCCAACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTTGT
CCTCTGATATATTTATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTACTT
CCATTAATTTTTTTTTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCCCA
AGGCAGGGAACTTCTATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGATT
GTTTTGGCACTGGTTCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGCAT
TTATTGGCAGAAGCCTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACATTT
GCCCCCTTTGTAACCTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGGAT
GACAGGAGGGAGATGTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAGAG
TGAACTCAGAGACGACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAAAT
GGGATCTAGAAAGCGGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGTTA
TAAATTTTCAATGATGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGATA
TTGTGAGAGGAATTGCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAATTG
TTGCTAGTACTTAGTTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTTCC
TAAGGTTTAATTTCCTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATGAG
GTTAAATTCTTTTATTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAGGG
AACTACATTTCCTCCAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGGGA
TCTTTGTCCTTAAGCTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTACCA
CTACAGTTTAGCAAATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAACCA
AAATGTCATGGTTGGAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAGAA
ACTGCTTGAACAGCTCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATAGA
TGTTTTAACACAACAGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTGGT
CATCTTAAGGTCATCTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTCAG
CCTTTGTTTAAACCTTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTTCA
CAGAAAATGAAGCAAAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACATT
TTCCAATTTCTATCCCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGTAG
TTGTTGAGATAATTTTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCTAA
GGACACTTATAGAGCTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGTAA
GGCAGCTTCACCTCTGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATTCT
TTACACACAAGAGACCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGGTT
AACAACAACATAAAAAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCACAT
CCTGTAGCTGTGGTTTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACCTT
TGGTCTGCACCTCCCACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTAAG
GAAAAACTCTGAGGCCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTGTA
TCCACAAAAAGGAATTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTGCA

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_1020nt
GTGAGAGTCAGTGAGCTCTCAGGAGATCTGCTGTTTGAAAGTGTGTAGCGCTTCCCCCTTCTCTCTCTCTGTCCTGCTGCACTATGGTGA
GATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTGCTGACGG
ATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGG
TCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGT
TTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTA
GGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGC
ATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCC
ACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCAT
TCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCATAAGCATATCATCC
ACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGACGCTTTATGATTTA
GAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAATCAAATTTTCTTAA

>In-frame_XXYLT1_ENST00000429994_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_5263nt
GTGAGAGTCAGTGAGCTCTCAGGAGATCTGCTGTTTGAAAGTGTGTAGCGCTTCCCCCTTCTCTCTCTCTGTCCTGCTGCACTATGGTGA
GATGTGTCCCTTCCGCCGTGATTGTGTGTTTCCTGAGGCCTCCCCAGCCAGGCAGAACTGTCATCTTCCACGATGTTGCTGTGCTGACGG
ATAAGCTCTTCCCCATCGTGGAGGCCATGCAGAAGCACTTCAGTGCTGGCTTGGGAACCTACTACAGTGACTCCATCTTCTTCCTCTCGG
TCGCCATGCATCAGATCATGCCCAAAGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACCAACATCCGGGAGTTGT
TTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGACAAGGAGAAGGCCTTA
GGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTATGCTACTTTCACTGAGC
ATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCAGCTATCCAGAATGCCC
ACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTACACAGGGCTGATGTCAT
TCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTACCATAAGCATATCATCC
ACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAATGACGCTTTATGATTTA
GAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAATAATCAAATTTTCTTAA
AACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAGAAGACTCTAAGTCCTG
TTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTGATTTATTCTCTCATTG
GGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAATATTTATTCCAAGACTC
AGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAATCCTGTGGTATTTATAT
GGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATGATCACATCTCTATACG
GCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCCTCCTTTCCATTCTTAT
AGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTACTCCAAGGCTGACTGTT
TCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAACAGACCTTTTTCTTCT
AAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAGAATGCCACAGGCATCT
TTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCAAAAACACTGTCTTAAC
ACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAACCCAGGAAATTATCTCA
TATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAAAAGCTTTGAATGTTGA
CTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTAAGTTGAAATTCCAGCC
AACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTTGTCCTCTGATATATTT
ATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTACTTCCATTAATTTTTTT
TTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCCCAAGGCAGGGAACTTC
TATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGATTGTTTTGGCACTGGT
TCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGCATTTATTGGCAGAAGC
CTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACATTTGCCCCCTTTGTAAC
CTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGGATGACAGGAGGGAGAT
GTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAGAGTGAACTCAGAGACG
ACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAAATGGGATCTAGAAAGC
GGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGTTATAAATTTTCAATGA
TGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGATATTGTGAGAGGAATT
GCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAATTGTTGCTAGTACTTAG
TTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTTCCTAAGGTTTAATTTC
CTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATGAGGTTAAATTCTTTTA
TTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAGGGAACTACATTTCCTC
CAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGGGATCTTTGTCCTTAAG
CTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTACCACTACAGTTTAGCAA
ATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAACCAAAATGTCATGGTTG
GAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAGAAACTGCTTGAACAGC
TCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATAGATGTTTTAACACAAC
AGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTGGTCATCTTAAGGTCAT
CTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTCAGCCTTTGTTTAAACC
TTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTTCACAGAAAATGAAGCA
AAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACATTTTCCAATTTCTATC
CCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGTAGTTGTTGAGATAATT
TTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCTAAGGACACTTATAGAG
CTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGTAAGGCAGCTTCACCTC
TGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATTCTTTACACACAAGAGA
CCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGGTTAACAACAACATAAA
AAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCACATCCTGTAGCTGTGGT
TTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACCTTTGGTCTGCACCTCC
CACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTAAGGAAAAACTCTGAGG
CCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTGTATCCACAAAAAGGAA
TTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTGCAGGCCTGCTGCCAAT

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000433971_chr3_189028175_+_766nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC
ACAGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTAC
CATAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAAT
GACGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAAT

>In-frame_XXYLT1_ENST00000355729_chr3_194877178_-_TPRG1_ENST00000345063_chr3_189028175_+_5009nt
ATGTGGCCACCTCGCTGCAAGGATCCAGGAAGGCAGAGTGCGGAGATCCTGCAGATCATTCAGCTGGACCTAGACCTGAAGTTTAAGACC
AACATCCGGGAGTTGTTTGAGGAATTTGACAGTTTCCTGCCAGGCGCCATCATCGGCATAGCCCGGGAGATGCAGCCAGTTTACAGGAGA
CAAGGAGAAGGCCTTAGGATCTACTGGGGGAGTCCGGAGGAGCAGTCTCTTCTGTCCCGCTGGAACCCATGGTCCACTGAAGTTCCTTAT
GCTACTTTCACTGAGCATCCTATGAAATACACCAGTGAGAAATTCCTTGAAATTTGCAAGTTGTCTGGGTTCATGTCTAAGCTTGTTCCA
GCTATCCAGAATGCCCACAAGAATTCAACTGGATCTGGAAGAGGAAAGAAACTGATGGTGTTAACTGAACCCATTTTGATTGAGACCTAC
ACAGGGCTGATGTCATTCATTGGAAACCGCAACAAACTTGGCTATTCCCTTGCCCGTGGGAGTATTGGTTTTTGAGAGTCTTTTTGGTAC
CATAAGCATATCATCCACAGATATGTCACTTTGAAAATTCCAGTTTGACCCACGCTATTTTTGGACTGAAACAATTAATTATTTTTAAAT
GACGCTTTATGATTTAGAAATTTAGTATTTCCGAAAATTTAAAAGCTTGATTGGACTGATAGATACACACTTTAGACCTCATACAAGAAT
AATCAAATTTTCTTAAAACTAGAAAATAAATGCTGCTGAGCCTATCAAATACTGTTATCAAATGAGTGCCTGATCATCAACTCAGGAAAG
AAGACTCTAAGTCCTGTTGCTTCAGCTCTCTAAATGTAGGCTTTTTTTTTTTTTTTTTTTTAGGTCTTGGTCTTCAGCCCTCTTATCCTG
ATTTATTCTCTCATTGGGGTCTCACTGTCTCTAGTATTTTAGCTACCACTTGATAAGGATGACTTCCAAATTTATATTCCCATTCCCAAT
ATTTATTCCAAGACTCAGTTTTGCATTTCTGACTGCTAATCATCTATATATCAGTGTCCCAGTGGCCTCTTAATTGAGCATTATCAAAAT
CCTGTGGTATTTATATGGTCCCAGTTATCCATCCCTGAAGTCTGTCAATTTTGATTTCTCTAAATTCCTTGCCATGACATCCTATATATG
ATCACATCTCTATACGGCTTAGCATTGTATTCCGATGCCCAGATGTCAAACTTGAAGCTCATTCTCTTATCAAAATTGTTCATGTATTCC
TCCTTTCCATTCTTATAGCTGTATTATTAGATCAGGTTTTTAATTCTGCTCAACCAATTATTACCACAGCCTGTTAAATGGAATCCCTAC
TCCAAGGCTGACTGTTTCAATCTATCCTACACTTGGTTTCTAGCTCATTTACTTATACCATCTTTTGTTCAAATATATATTTTTTAATAA
CAGACCTTTTTCTTCTAAAGAAATCTTTTGTAGAAGCAGCATATACGAAGCAGATAAAAGTAGGTTCAATGCGGTTGGAGTGAAGATGAG
AATGCCACAGGCATCTTTCTTTCTAGGCCTCAGAGGTGCTGCATATGGAATGTCCATGGATCGCAGAGGGTTTTGAAGACCATGTTTTCA
AAAACACTGTCTTAACACTCTATTGTCATTGCTCTTTTCCCTCTTATTTCCTCTTTGTCTCTTCCCGACTTAGATCTAATTTTCAACAAC
CCAGGAAATTATCTCATATGTTTGCATCTCTCAAGTTTCTTTTCTTTTTTCTTTCAGAGTCTTATTTTATCTAAATTTATGTAGAAAAAA
AAGCTTTGAATGTTGACTACATAGACATTACTACAATAAGCTTTTTGCCTTTCCCAAGACTCAAAATTGACACATCTTTGTTGATGTTTA
AGTTGAAATTCCAGCCAACTTTTTTTTGACTTTTATGTGAAGTTTAAAGTCTTTTCTTTGAAAAGCTTGCTTCCTCAATTTCAAAGATTT
GTCCTCTGATATATTTATAAACATCAATTTAATGCAGACATTCAAACCCTAAACCTTGAATAACTCTTATTTTATTTTGTCTTTGTTTAC
TTCCATTAATTTTTTTTTCTTTCCCTCTCTTCCGCCTTTACAGCACCCACTTTTTCTTCCCCCCATGATGGCAAATATTGTTATAGTCCC
CAAGGCAGGGAACTTCTATTCAGACTGTAAAAGGAAATGTTGAAATCCATAGCTGTCCTGTCAACAGTAGTGGAATGAAAAGTCGTTGGA
TTGTTTTGGCACTGGTTCTGAAGCAGGCATAATTGGCAAATTATTATAATACTGCTGCCCGAAAATCCCCATTTGCCTCAAGATAGTGGC
ATTTATTGGCAGAAGCCTCTGAAATGTCCAGCACATTCTTTTGAGTTACCATTTAAGGATCAGCCTGACAATCGACTTCTCTCTGCACAT
TTGCCCCCTTTGTAACCTAAGCCAGACTGTTCCCAAATGACCTTCTAAAGGACACAGTGCACCATCATCAATGGAAACAGTTCAGAAAGG
ATGACAGGAGGGAGATGTTTCTTAGTTCTGAGAGCCAGTCTGTAACAATGGGATAAGCATTTAATGGAATCAAAGCTGTTTTGCATAAAG
AGTGAACTCAGAGACGACAAGAGGGTCTTTATGAATTCCCTTCACATTTTGTAAAAACTGTCATATATAGGCTATCCCCTTAATTGATAA
ATGGGATCTAGAAAGCGGTATTATGACCAGAGGGTGAGAAGATTTAGGAATTTGGATAGCAGTTCAAGATAAGAAAGAACTTCTTATAGT
TATAAATTTTCAATGATGGAATGGGTTGCTTCTTTAAACAGTGAGCCCACCATCACTTGGTATGTTCAAGGAAAGACTAGATAAAGTCGA
TATTGTGAGAGGAATTGCTGTATGATACCGTTTGGAGAAATGATTGACATAATCTTTTAAGGCCGGTGACCCTATCATTTTCCAAATAAT
TGTTGCTAGTACTTAGTTAATTAGACCCATTTTTTTCTTAGGAAAGAGTTGGATCAATCATGGGAGACCCTGAAAAATTTCCTTACCTTT
CCTAAGGTTTAATTTCCTCTTCTGCGAAATGGAGACAATTATATTACTTTTGCTTATTTCATAAAGATCTTGTGAGGATTCAATGAAATG
AGGTTAAATTCTTTTATTAAACAGAAAGTTTTGAGTATTTGCCTAGAGAGTGATGTGACTTTTGCAGCAGAAGGTGGGAAAACATCCAAG
GGAACTACATTTCCTCCAGAAATTGTTTCTTCATTACCATCGACCTACTGATTATGGTTTTCTCATTTTACACTTGGTGTTCTTACTTGG
GATCTTTGTCCTTAAGCTCAACAGGGAGCCACAACCCAGGGGACCTATGTGTACACTTGGAGTTTTTATCAGACTATCATTTGAACTTAC
CACTACAGTTTAGCAAATGGCATGATGAGTTTGATTGATAATAGGAGTAGACGCAAGATACATTAAGTAGAGTACAAAGCATTTCATAAC
CAAAATGTCATGGTTGGAGGTCTTCATTATTCGGTCTTTATCTCATTCAGGAATTTCCACTTGAAAAATCTCTGATAAGCTTTATTTCAG
AAACTGCTTGAACAGCTCCACTGACAAATGCCTCACTATCTTCTGATACATCGTAGGCAGTTCTGAGGGTGAGAAAGTTCAAAGCAGATA
GATGTTTTAACACAACAGGAGGACTTTTAAACAATCACCAGGACTCACTCCTCGGTGGTCAATTGGGCCTGTTTGGAGGCCTGACCTTTG
GTCATCTTAAGGTCATCTAAGGCAGAAAAGAGAAGCTCACTTATAAGTTGGCACTTCTGAATCATTTGCCTTGAGGTCCATTTTTTATTC
AGCCTTTGTTTAAACCTTCTTAGGAAGCCAGTTTGTAGAGTTCTGGGGATAAGAAGGCAGAAAAACCATGTCAATTCAGTGCTTTTATTT
CACAGAAAATGAAGCAAAGGCCTAGAAACTAGAAAGACATTTCTCAAAAAGAAGATGGTGAACTTTTGGAAATACTGAGATTAGACTACA
TTTTCCAATTTCTATCCCTAGCCCACTGCTCTTTCCAATATAATATCTGTATTCCATGGGAAAGACATGCCATCTGAATTGATGTATCGT
AGTTGTTGAGATAATTTTGAAATGAGAAAACAATAGGGCACAGTCGTTTGGGAAGAATTTCCAGAAATTGCCATCATTTTCTTAAAGGCT
AAGGACACTTATAGAGCTCTCCGATTTCCTATCTGATAAAAAAAGCCCAAACAAAGCTGCGGAAGCTGGCAGAGCCAGCAGATATTTTGT
AAGGCAGCTTCACCTCTGCTGGCATTTTGTGGGGCAGGAGAGGGGGAGGGCAAAGGTATTAAATTTAGGCTTAAAAGCTCCTCAGAAATT
CTTTACACACAAGAGACCAAGTTGGAGAAAAGAAGATGACTTGTGCCAAGGGGAAGAAAGAGAGAGACTAATGCCTGTGGTTTTCAAAGG
TTAACAACAACATAAAAAAGCCAAGGTATTTGCACAGGGATGAATGCTCATTGGCTCTTGGCCAACAATTATACAAGGGCTTGTGCCCAC
ATCCTGTAGCTGTGGTTTAGGGACGCTGCTCATGAGTGACTTCTTATGCTTAGTGGCAGGAAACTTTAGTCACTGATGTGTAAACTCACC
TTTGGTCTGCACCTCCCACAACGTGCTCCGAAAGCAGTTAGGGGACTAGGCCTCTTGATTTCCTTGTAGATACCAGTTCCCCAGAAGCTA
AGGAAAAACTCTGAGGCCTTGGAGTTACTGAGAGTGGACCAATACTTGTCTTATTCTACCTGATTTTGGCAACTGCTTAGGGTTCTTCTG
TATCCACAAAAAGGAATTATGATATCCTCTGCTAAACCCTCTCTTTAGCCTCAAAGCCCAAGACCAAAAAAAATGAGCCATATTTCATTG


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FusionGenePPI for XXYLT1_TPRG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
XXYLT1ELAVL1, CUL4A, SHMT2, MOV10, NXF1, FAM63B, SCN3B, IZUMO1, HAUS7TPRG1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000310380-34263_266261394target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000355729-23263_26658191target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000356740-12263_2660188target proteins
HgeneXXYLT1chr3:194877178chr3:189028175ENST00000437101-45263_26658191target proteins


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for XXYLT1_TPRG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for XXYLT1_TPRG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource