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Fusion gene ID: 42225 |
FusionGeneSummary for XRCC6_ARSB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: XRCC6_ARSB | Fusion gene ID: 42225 | Hgene | Tgene | Gene symbol | XRCC6 | ARSB | Gene ID | 2547 | 411 |
| Gene name | X-ray repair cross complementing 6 | arylsulfatase B | |
| Synonyms | CTC75|CTCBF|G22P1|KU70|ML8|TLAA | ASB|G4S|MPS6 | |
| Cytomap | 22q13.2 | 5q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | X-ray repair cross-complementing protein 65'-dRP lyase Ku705'-deoxyribose-5-phosphate lyase Ku7070 kDa subunit of Ku antigenATP-dependent DNA helicase 2 subunit 1ATP-dependent DNA helicase II, 70 kDa subunitCTC box binding factor 75 kDa subunitDNA | arylsulfatase BN-acetylgalactosamine-4-sulfatase | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P12956 | P15848 | |
| Ensembl transtripts involved in fusion gene | ENST00000360079, ENST00000402580, ENST00000428575, ENST00000359308, ENST00000405878, ENST00000405506, | ENST00000264914, ENST00000396151, ENST00000565165, ENST00000521800, | |
| Fusion gene scores | * DoF score | 7 X 5 X 7=245 | 5 X 3 X 4=60 |
| # samples | 7 | 4 | |
| ** MAII score | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: XRCC6 [Title/Abstract] AND ARSB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | XRCC6 | GO:0002218 | activation of innate immune response | 28712728 |
| Hgene | XRCC6 | GO:0045860 | positive regulation of protein kinase activity | 22504299 |
| Hgene | XRCC6 | GO:0045893 | positive regulation of transcription, DNA-templated | 12145306 |
| Hgene | XRCC6 | GO:0051290 | protein heterotetramerization | 24095731 |
| Hgene | XRCC6 | GO:0071480 | cellular response to gamma radiation | 26359349 |
| Hgene | XRCC6 | GO:0097680 | double-strand break repair via classical nonhomologous end joining | 24095731 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-XV-AAZY-01A | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000360079 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000360079 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000360079 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| 5CDS-intron | ENST00000360079 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000402580 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000402580 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000402580 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| 5CDS-intron | ENST00000402580 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000428575 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000428575 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000428575 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-intron | ENST00000428575 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000359308 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000359308 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000359308 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| 5CDS-intron | ENST00000359308 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000405878 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000405878 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| In-frame | ENST00000405878 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| 5CDS-intron | ENST00000405878 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000405506 | ENST00000264914 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000405506 | ENST00000396151 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-3CDS | ENST00000405506 | ENST00000565165 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
| intron-intron | ENST00000405506 | ENST00000521800 | XRCC6 | chr22 | 42024234 | + | ARSB | chr5 | 78265015 | - |
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FusionProtFeatures for XRCC6_ARSB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| XRCC6 | ARSB |
| Single-stranded DNA-dependent ATP-dependent helicase.Has a role in chromosome translocation. The DNA helicase IIcomplex binds preferentially to fork-like ends of double-strandedDNA in a cell cycle-dependent manner. It works in the 3'-5'direction. Binding to DNA may be mediated by XRCC6. Involved inDNA non-homologous end joining (NHEJ) required for double-strandbreak repair and V(D)J recombination. The XRCC5/6 dimer acts asregulatory subunit of the DNA-dependent protein kinase complexDNA-PK by increasing the affinity of the catalytic subunit PRKDCto DNA by 100-fold. The XRCC5/6 dimer is probably involved instabilizing broken DNA ends and bringing them together. Theassembly of the DNA-PK complex to DNA ends is required for theNHEJ ligation step. Required for osteocalcin gene expression.Probably also acts as a 5'-deoxyribose-5-phosphate lyase (5'-dRPlyase), by catalyzing the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site near double-strand breaks. 5'-dRPlyase activity allows to 'clean' the termini of abasic sites, aclass of nucleotide damage commonly associated with strand breaks,before such broken ends can be joined. The XRCC5/6 dimer togetherwith APEX1 acts as a negative regulator of transcription. Plays arole in the regulation of DNA virus-mediated innate immuneresponse by assembling into the HDP-RNP complex, a complex thatserves as a platform for IRF3 phosphorylation and subsequentinnate immune response activation through the cGAS-STING pathway.{ECO:0000269|PubMed:12145306, ECO:0000269|PubMed:20383123,ECO:0000269|PubMed:20493174, ECO:0000269|PubMed:2466842,ECO:0000269|PubMed:28712728, ECO:0000269|PubMed:7957065,ECO:0000269|PubMed:8621488, ECO:0000269|PubMed:9742108}. | Removes sulfate groups from chondroitin-4-sulfate (C4S)and regulates its degradation (PubMed:19306108). Involved in theregulation of cell adhesion, cell migration and invasion incolonic epithelium (PubMed:19306108). In the central nervoussystem, is a regulator of neurite outgrowth and neuronalplasticity, acting through the control of sulfateglycosaminoglycans and neurocan levels (By similarity).{ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 11_29 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 2_61 | 65 | 610 | Compositional bias | Note=Ser-rich (potentially targets for phosphorylation) |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 11_29 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 2_61 | 65 | 610 | Compositional bias | Note=Ser-rich (potentially targets for phosphorylation) |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 11_29 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 2_61 | 65 | 610 | Compositional bias | Note=Ser-rich (potentially targets for phosphorylation) |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 330_342 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 330_342 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 330_342 | 65 | 610 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 261_468 | 65 | 610 | Domain | Note=Ku |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 573_607 | 65 | 610 | Domain | SAP |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 261_468 | 65 | 610 | Domain | Note=Ku |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 573_607 | 65 | 610 | Domain | SAP |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 261_468 | 65 | 610 | Domain | Note=Ku |
| Hgene | >XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 573_607 | 65 | 610 | Domain | SAP |
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FusionGeneSequence for XRCC6_ARSB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_495aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF VDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSR >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_495aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF VDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSR >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_495aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF VDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSR >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_495aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF VDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSR >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_375aa MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQIRTGLQHQIIWPCQPSCVPLDEKLL PQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_1485nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC GTGGACTCTTCACCGTGTCCCAGGAACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTC CATGCTGCAATTAGACATGGAAATTGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTT TCTGAGATACCCTCATCAGACCCACCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGA GAATATCCTCACATCGTCACAAAGCTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCC >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_1485nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC GTGGACTCTTCACCGTGTCCCAGGAACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTC CATGCTGCAATTAGACATGGAAATTGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTT TCTGAGATACCCTCATCAGACCCACCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGA GAATATCCTCACATCGTCACAAAGCTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCC >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_1485nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC GTGGACTCTTCACCGTGTCCCAGGAACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTC CATGCTGCAATTAGACATGGAAATTGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTT TCTGAGATACCCTCATCAGACCCACCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGA GAATATCCTCACATCGTCACAAAGCTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCC >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_1485nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC GTGGACTCTTCACCGTGTCCCAGGAACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTC CATGCTGCAATTAGACATGGAAATTGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTT TCTGAGATACCCTCATCAGACCCACCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGA GAATATCCTCACATCGTCACAAAGCTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCC >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1125nt ATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTAT AAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTT GACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTG CCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGC CGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTC ACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCT ATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAG GAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAAT GTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGT AATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAG AAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAG CCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_4915nt GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTT TTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTT TACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATA CTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATC TCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATG GCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAG AGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCC AAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGC TCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAAT GGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCC ACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAA CCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTGTCCCAGGAACA GCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTCCATGCTGCAATTAGACATGGAAATTGGA AACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTTTCTGAGATACCCTCATCAGACCCACCAA CCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGAGAATATCCTCACATCGTCACAAAGCTCC TGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCCCGCTGTGATCCCAAGGCCACTGGGGTGT GGGGCCCTTGGATGTAGGATTTCAGGGAGGCTAGAAAACCTTTCAATTGGAAGTTGGACCTCAGGCCTTTTCTCACGACTCTTGTCTCAT TTGTTATCCCAACCTGGGTTCACTTGGCCCTTCTCTTGCTCTTAAACCACACCGAGGTGTCTAATTTCAACCCCTAATGCATTTAAGAAG CTGATAAAATCTGCAACACTCCTGCTGTTGGCTGGAGCATGTGTCTAGAGGTGGGGGTGGCTGGGTTTATCCCCCTTTCCTAAGCCTTGG GACAGCTGGGAACTTAACTTGAAATAGGAAGTTCTCACTGAATCCTGGAGGCTGGAACAGCTGGCTCTTTTAGACTCACAAGTCAGACGT TCGATTCCCCTCTGCCAATAGCCAGTTTTATTGGAGTGAATCACATTTCTTACGCAAATGAAGGGAGCAGACAGTGATTAATGGTTCTGT TGGCCAAGGCTTCTCCCTGTCGGTGAAGGATCATGTTCAGGCACTCCAAGTGAACCACCCCTCTTGGTTCACCCCTTACTCACTTATCTC ATCACAGAGCATAAGGCCCATTTTGTTGTTCAGGTCAACAGCAAAATGCCTGCACCATGACTGTGGCTTTTAAAATAAAGAAATGTGTTT TTATCGTAATTTATTTCCCCCCAGCCATTGCTCACTCTGTCTAGACTTCCTGCCACTTCCAATTCTTCTGTGGCTTTTCCTGCCTTTCCT TTTGACCTCAGTAGTCCTATCCCTGGGAAGGCCACTTTGCTTCTCTACCTGAGCACCCCTGATTTCTGGAACGCTGCTGAGCCCTGCCTT ACTTTTGCCCCTAGGGCTGAAGCTAGAGGCCTCCCCGTAATAGGCGGTGGAGTTGCTCTGTGAGGATGTTCATGGTAGACACTAAGAGGG CTGGGTGGGAGATGCTTGGCTCTGTGGCATCTGTTCAGCGAGGCTTTTCCTATATTGCATGGAGTTAGTCATTGTGATTGTAGCTTTATT TCATAATATATTAAGACTTGCACTGCTATTTACTAGCAGTGAGAAGAAACCTCAGGAAAGGATATGAAAAAGCAAGTGGCCAGTGTCTGG GATACTGGGCCTTGGTAAAGCAGAGGAGGGCACACCCACAGTCCTCTTATTCTCTGTTTTACTGCTTGTTTTGAGGTTCTGGGGTCTGGC AAAGAGGATGCAGTTTGACACCTGCAGCCCTTTCTCAATCCCACTAATGTCTTACTAATGTGGAACAGTCCATATTAGCTCCAGAGAGTG TCAAACCCAGAGAAATGTGTGCAAAAATGATACTCTTTTCTGCATTAGCCCCACCATTGTGTTCACCAATGCTTGGAACACTGCCTGAAG GCACTCATTTTTTAATTTTTATTTTATTTTTAATTTTTTATATCTTTATGAGACGATCTCACTCTGTCACCAGGTTGGAGTACAGTGGTA CAATCACAACTCACCGTAGCCTCAAACTCCTGGGCTCAAGTGATTCTCCCACCTCAGGCACCCAAATAGCTGGAACTACAGGCATATACC GCCACACCCAGCTAATTTTATTTTTTGAAAAGACAAGGTTCCCTATGTTGCCCAGCTGGTCTTAAACTCCTGGGCTCCAGCAATTATCCC AGCTTGGGCTCCAAAAGTGCTGGGATTACAGGCATGAGTCACCATGCCTGGCCTCATTTTTTAAAACAAATGAATAAATGGACAAATGAG TAAATGAGAAAGTCTCACACCATGAAAGATGCTAGTCCAATGAGCTGAATACAGAGGTAATATAAATGTCTTCCAGCTGTTGCTTTTCTG TTCTCAAGCTGCCCCTCCTGGGGTAGGAGCATAATCTACATCACTGGGCAGTCACAGGACACTCTATAGCAAGGTTGTAGCGTCCTCTCC AGTGGGGGGAGAAAAGGAACTGTGCCTACCAAAGGTACTCTCTTGTCAGCAATTTCCATTTCTATACTTTATGGGACACTAGAAACTAAA AGCAACAAATAATCTGATATAAGTCCTTGTATAGTCATCCTTCAATTCAGTAGCAATATTTTCTGGTCACTACTAACCTGTATTGTATTA AAATGAGACTATTGGAAGGAAATGGTGCTAAAACTAATAACATCTCTTACCAACCTTTACCCAACTCCTGGGTTGGCAAACAGCTGACCA AACTGCCATCACCTCCCACTTGGAAGTGTATGGCCGACAGCATGAAATAGCTGAGCCCAGATGTTCCTTCTGCATCCTCCGAATCCCAGG GCTGGGTGTAGGTAGCCGTTGGAGGCCATCGCTACAGGGCACCTATCTGTTATCGCTGCTGTCCTCCCAACAGCTGTCTCCAGTTCTAGT TCCTTGGTTTTCAGGCACAGTGGGGGATGTTCTGCACCCAGTGGACTTCAAAAGAGTTTTGAAGACTTAATTTTTTGTAAAACAAGTACT TGAGATTTTGGTTTATCCATAATAGAATGTATTTCATTAGATTCTCTGATTCTATATAAGAATGTGAAAAGATTGATATATTGTTGTTAG AAATAATGTTATTTCTTTCCAATTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGAT CTCGGCTCACTGCAGCCTCTAACTCCCAGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGATTACAGGCATACACCACCAC GCCTGGCTATGTTTTGTATTTTTCGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCC ACTTCAGCTTCCCAAAGCACTGGGATTACAGGTGTGAGCCACTGTGCCCGGCAAATTTTTTTACCTTTACAGAAGGTTTTGCTTATTTAA TTGTGAGCTCATTTTTCTTTGTTACTTTTGTCCCCCCAGATTTGGGGGACAAAATAAAATTAATCTTTTAAAATGTGTCAGCCATATGTA TGGGGCTTCCATTTGGGGTGAGGAGAAAGTTCTGGAACTAGATAGTGGTCATGGTTATACAACATCATAAATGCAATTACTGCCACTGAA TTGTATGTTTTAAAGTGGTTAAAATGTTAAGTTTTATGTTTTATTACAATTTTTAAATGTGTCAACCAACTTTATAGTACATAAATTATA >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1942nt GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTT TTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTT TACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATA CTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATC TCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATG GCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAG AGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCC AAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGC TCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAAT GGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCC ACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAA CCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGT GCTCGCTGCTGTTGTAGCTACCACCAACTTTCTACTGAAGATGATAACCCAGGGCATAAGAAATGACTTCAGACCCAAGGTTCTGAAAGG GCCCCTCAAGGCCTCGGGTGGCTCCTGCAGAAGTGGCAGAAGAGGCGGGAACTAGGAACCTGGCATCATAGGAAAAGTGCCTTCTCCAAG AAAGAAGGGGCCCCAGGAGGCTGTCTTACTTAGATCAACCATAAACTACCACAGATGGGTCATTTCTTATATTATTTCAAAATATCTTTG AAGATGAGAATTCATTTGTGTCCTTCATAGACCAAAGTTCTTTGTGTTACCTTTTCCCAAAAGTAAATTCCTTTCCCTTTATTCATTCCT TGTGGAAATAAAATGCAAGCCCTTTATACTTGTCTTACAGTAATATGGCACATGTAGCTTACTTTTGAGCATCCCAGTGAATAATGTTTG GAACTTTTCTTATTACCTAATAGCATATAGAGAAGAGTGAAGTCAGCTAAAAACAGAAATTTTGAAAAGCCATCTTCAGGAAAATGTAGG >In-frame_XRCC6_ENST00000360079_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1398nt GTAGGAAGGGGCGGGGCTTTGCCGAAGGGGGCGGGGCTCTCGCTGATGGGTTGGCTTTCGTCAGGGACATAGGTAGAAGCTGGTTGGGGA GTGTGCGTGCCAGCCTGACGCGATATAGTGCGCACATGCGTGATGACGTAGAGGGCGTTGATTGGGACCGAGTACAGGGCCCGCGCATGC GTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAA CCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTT TTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTT TACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATA CTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATC TCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATG GCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAG AGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCC AAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGC TCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAAT GGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCC ACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAA CCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGT >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_4739nt ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTG ATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACA GGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGT TATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGA TATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGA GATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCA CCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTT ATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGT GGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGA AAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTC ATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGG AAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTGTCCCAGG AACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTCCATGCTGCAATTAGACATGGAAAT TGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTTTCTGAGATACCCTCATCAGACCCA CCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGAGAATATCCTCACATCGTCACAAAG CTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCCCGCTGTGATCCCAAGGCCACTGGG GTGTGGGGCCCTTGGATGTAGGATTTCAGGGAGGCTAGAAAACCTTTCAATTGGAAGTTGGACCTCAGGCCTTTTCTCACGACTCTTGTC TCATTTGTTATCCCAACCTGGGTTCACTTGGCCCTTCTCTTGCTCTTAAACCACACCGAGGTGTCTAATTTCAACCCCTAATGCATTTAA GAAGCTGATAAAATCTGCAACACTCCTGCTGTTGGCTGGAGCATGTGTCTAGAGGTGGGGGTGGCTGGGTTTATCCCCCTTTCCTAAGCC TTGGGACAGCTGGGAACTTAACTTGAAATAGGAAGTTCTCACTGAATCCTGGAGGCTGGAACAGCTGGCTCTTTTAGACTCACAAGTCAG ACGTTCGATTCCCCTCTGCCAATAGCCAGTTTTATTGGAGTGAATCACATTTCTTACGCAAATGAAGGGAGCAGACAGTGATTAATGGTT CTGTTGGCCAAGGCTTCTCCCTGTCGGTGAAGGATCATGTTCAGGCACTCCAAGTGAACCACCCCTCTTGGTTCACCCCTTACTCACTTA TCTCATCACAGAGCATAAGGCCCATTTTGTTGTTCAGGTCAACAGCAAAATGCCTGCACCATGACTGTGGCTTTTAAAATAAAGAAATGT GTTTTTATCGTAATTTATTTCCCCCCAGCCATTGCTCACTCTGTCTAGACTTCCTGCCACTTCCAATTCTTCTGTGGCTTTTCCTGCCTT TCCTTTTGACCTCAGTAGTCCTATCCCTGGGAAGGCCACTTTGCTTCTCTACCTGAGCACCCCTGATTTCTGGAACGCTGCTGAGCCCTG CCTTACTTTTGCCCCTAGGGCTGAAGCTAGAGGCCTCCCCGTAATAGGCGGTGGAGTTGCTCTGTGAGGATGTTCATGGTAGACACTAAG AGGGCTGGGTGGGAGATGCTTGGCTCTGTGGCATCTGTTCAGCGAGGCTTTTCCTATATTGCATGGAGTTAGTCATTGTGATTGTAGCTT TATTTCATAATATATTAAGACTTGCACTGCTATTTACTAGCAGTGAGAAGAAACCTCAGGAAAGGATATGAAAAAGCAAGTGGCCAGTGT CTGGGATACTGGGCCTTGGTAAAGCAGAGGAGGGCACACCCACAGTCCTCTTATTCTCTGTTTTACTGCTTGTTTTGAGGTTCTGGGGTC TGGCAAAGAGGATGCAGTTTGACACCTGCAGCCCTTTCTCAATCCCACTAATGTCTTACTAATGTGGAACAGTCCATATTAGCTCCAGAG AGTGTCAAACCCAGAGAAATGTGTGCAAAAATGATACTCTTTTCTGCATTAGCCCCACCATTGTGTTCACCAATGCTTGGAACACTGCCT GAAGGCACTCATTTTTTAATTTTTATTTTATTTTTAATTTTTTATATCTTTATGAGACGATCTCACTCTGTCACCAGGTTGGAGTACAGT GGTACAATCACAACTCACCGTAGCCTCAAACTCCTGGGCTCAAGTGATTCTCCCACCTCAGGCACCCAAATAGCTGGAACTACAGGCATA TACCGCCACACCCAGCTAATTTTATTTTTTGAAAAGACAAGGTTCCCTATGTTGCCCAGCTGGTCTTAAACTCCTGGGCTCCAGCAATTA TCCCAGCTTGGGCTCCAAAAGTGCTGGGATTACAGGCATGAGTCACCATGCCTGGCCTCATTTTTTAAAACAAATGAATAAATGGACAAA TGAGTAAATGAGAAAGTCTCACACCATGAAAGATGCTAGTCCAATGAGCTGAATACAGAGGTAATATAAATGTCTTCCAGCTGTTGCTTT TCTGTTCTCAAGCTGCCCCTCCTGGGGTAGGAGCATAATCTACATCACTGGGCAGTCACAGGACACTCTATAGCAAGGTTGTAGCGTCCT CTCCAGTGGGGGGAGAAAAGGAACTGTGCCTACCAAAGGTACTCTCTTGTCAGCAATTTCCATTTCTATACTTTATGGGACACTAGAAAC TAAAAGCAACAAATAATCTGATATAAGTCCTTGTATAGTCATCCTTCAATTCAGTAGCAATATTTTCTGGTCACTACTAACCTGTATTGT ATTAAAATGAGACTATTGGAAGGAAATGGTGCTAAAACTAATAACATCTCTTACCAACCTTTACCCAACTCCTGGGTTGGCAAACAGCTG ACCAAACTGCCATCACCTCCCACTTGGAAGTGTATGGCCGACAGCATGAAATAGCTGAGCCCAGATGTTCCTTCTGCATCCTCCGAATCC CAGGGCTGGGTGTAGGTAGCCGTTGGAGGCCATCGCTACAGGGCACCTATCTGTTATCGCTGCTGTCCTCCCAACAGCTGTCTCCAGTTC TAGTTCCTTGGTTTTCAGGCACAGTGGGGGATGTTCTGCACCCAGTGGACTTCAAAAGAGTTTTGAAGACTTAATTTTTTGTAAAACAAG TACTTGAGATTTTGGTTTATCCATAATAGAATGTATTTCATTAGATTCTCTGATTCTATATAAGAATGTGAAAAGATTGATATATTGTTG TTAGAAATAATGTTATTTCTTTCCAATTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTG TGATCTCGGCTCACTGCAGCCTCTAACTCCCAGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGATTACAGGCATACACCA CCACGCCTGGCTATGTTTTGTATTTTTCGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCC ACCCACTTCAGCTTCCCAAAGCACTGGGATTACAGGTGTGAGCCACTGTGCCCGGCAAATTTTTTTACCTTTACAGAAGGTTTTGCTTAT TTAATTGTGAGCTCATTTTTCTTTGTTACTTTTGTCCCCCCAGATTTGGGGGACAAAATAAAATTAATCTTTTAAAATGTGTCAGCCATA TGTATGGGGCTTCCATTTGGGGTGAGGAGAAAGTTCTGGAACTAGATAGTGGTCATGGTTATACAACATCATAAATGCAATTACTGCCAC TGAATTGTATGTTTTAAAGTGGTTAAAATGTTAAGTTTTATGTTTTATTACAATTTTTAAATGTGTCAACCAACTTTATAGTACATAAAT >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1766nt ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTG ATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACA GGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGT TATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGA TATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGA GATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCA CCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTT ATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGT GGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGA AAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTC ATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGG AAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCT GAGTGCTCGCTGCTGTTGTAGCTACCACCAACTTTCTACTGAAGATGATAACCCAGGGCATAAGAAATGACTTCAGACCCAAGGTTCTGA AAGGGCCCCTCAAGGCCTCGGGTGGCTCCTGCAGAAGTGGCAGAAGAGGCGGGAACTAGGAACCTGGCATCATAGGAAAAGTGCCTTCTC CAAGAAAGAAGGGGCCCCAGGAGGCTGTCTTACTTAGATCAACCATAAACTACCACAGATGGGTCATTTCTTATATTATTTCAAAATATC TTTGAAGATGAGAATTCATTTGTGTCCTTCATAGACCAAAGTTCTTTGTGTTACCTTTTCCCAAAAGTAAATTCCTTTCCCTTTATTCAT TCCTTGTGGAAATAAAATGCAAGCCCTTTATACTTGTCTTACAGTAATATGGCACATGTAGCTTACTTTTGAGCATCCCAGTGAATAATG TTTGGAACTTTTCTTATTACCTAATAGCATATAGAGAAGAGTGAAGTCAGCTAAAAACAGAAATTTTGAAAAGCCATCTTCAGGAAAATG >In-frame_XRCC6_ENST00000402580_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1222nt ATGCGTGGATTGTCGTCTTCTGTCCAAGTTGGTCGCTTCCCTGCGCCAAAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTAC AAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTG ATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACA GGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGT TATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGA TATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGA GATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCA CCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTT ATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGT GGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGA AAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTC ATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGG AAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCT >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_5328nt GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA GAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCA GAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTG TGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTA CCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTG TACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTC AACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGT GCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTC CCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAA CGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTT TGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGC CAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCT GCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTGTCCCAGGAACAGCATGGCTCCAGCAAAGGATGACTCTTCTCTTCCAGA ATATTCAGCCTTTAACACATCTGTCCATGCTGCAATTAGACATGGAAATTGGAAACTCCTCACGGGCTACCCAGGCTGTGGTTACTGGTT CCCTCCACCGTCTCAATACAATGTTTCTGAGATACCCTCATCAGACCCACCAACCAAGACCCTCTGGCTCTTTGATATTGATCGGGACCC TGAAGAAAGACATGACCTGTCCAGAGAATATCCTCACATCGTCACAAAGCTCCTGTCCCGCCTACAGTTCTACCATAAACACTCAGTCCC CGTGTACTTCCCTGCACAGGACCCCCGCTGTGATCCCAAGGCCACTGGGGTGTGGGGCCCTTGGATGTAGGATTTCAGGGAGGCTAGAAA ACCTTTCAATTGGAAGTTGGACCTCAGGCCTTTTCTCACGACTCTTGTCTCATTTGTTATCCCAACCTGGGTTCACTTGGCCCTTCTCTT GCTCTTAAACCACACCGAGGTGTCTAATTTCAACCCCTAATGCATTTAAGAAGCTGATAAAATCTGCAACACTCCTGCTGTTGGCTGGAG CATGTGTCTAGAGGTGGGGGTGGCTGGGTTTATCCCCCTTTCCTAAGCCTTGGGACAGCTGGGAACTTAACTTGAAATAGGAAGTTCTCA CTGAATCCTGGAGGCTGGAACAGCTGGCTCTTTTAGACTCACAAGTCAGACGTTCGATTCCCCTCTGCCAATAGCCAGTTTTATTGGAGT GAATCACATTTCTTACGCAAATGAAGGGAGCAGACAGTGATTAATGGTTCTGTTGGCCAAGGCTTCTCCCTGTCGGTGAAGGATCATGTT CAGGCACTCCAAGTGAACCACCCCTCTTGGTTCACCCCTTACTCACTTATCTCATCACAGAGCATAAGGCCCATTTTGTTGTTCAGGTCA ACAGCAAAATGCCTGCACCATGACTGTGGCTTTTAAAATAAAGAAATGTGTTTTTATCGTAATTTATTTCCCCCCAGCCATTGCTCACTC TGTCTAGACTTCCTGCCACTTCCAATTCTTCTGTGGCTTTTCCTGCCTTTCCTTTTGACCTCAGTAGTCCTATCCCTGGGAAGGCCACTT TGCTTCTCTACCTGAGCACCCCTGATTTCTGGAACGCTGCTGAGCCCTGCCTTACTTTTGCCCCTAGGGCTGAAGCTAGAGGCCTCCCCG TAATAGGCGGTGGAGTTGCTCTGTGAGGATGTTCATGGTAGACACTAAGAGGGCTGGGTGGGAGATGCTTGGCTCTGTGGCATCTGTTCA GCGAGGCTTTTCCTATATTGCATGGAGTTAGTCATTGTGATTGTAGCTTTATTTCATAATATATTAAGACTTGCACTGCTATTTACTAGC AGTGAGAAGAAACCTCAGGAAAGGATATGAAAAAGCAAGTGGCCAGTGTCTGGGATACTGGGCCTTGGTAAAGCAGAGGAGGGCACACCC ACAGTCCTCTTATTCTCTGTTTTACTGCTTGTTTTGAGGTTCTGGGGTCTGGCAAAGAGGATGCAGTTTGACACCTGCAGCCCTTTCTCA ATCCCACTAATGTCTTACTAATGTGGAACAGTCCATATTAGCTCCAGAGAGTGTCAAACCCAGAGAAATGTGTGCAAAAATGATACTCTT TTCTGCATTAGCCCCACCATTGTGTTCACCAATGCTTGGAACACTGCCTGAAGGCACTCATTTTTTAATTTTTATTTTATTTTTAATTTT TTATATCTTTATGAGACGATCTCACTCTGTCACCAGGTTGGAGTACAGTGGTACAATCACAACTCACCGTAGCCTCAAACTCCTGGGCTC AAGTGATTCTCCCACCTCAGGCACCCAAATAGCTGGAACTACAGGCATATACCGCCACACCCAGCTAATTTTATTTTTTGAAAAGACAAG GTTCCCTATGTTGCCCAGCTGGTCTTAAACTCCTGGGCTCCAGCAATTATCCCAGCTTGGGCTCCAAAAGTGCTGGGATTACAGGCATGA GTCACCATGCCTGGCCTCATTTTTTAAAACAAATGAATAAATGGACAAATGAGTAAATGAGAAAGTCTCACACCATGAAAGATGCTAGTC CAATGAGCTGAATACAGAGGTAATATAAATGTCTTCCAGCTGTTGCTTTTCTGTTCTCAAGCTGCCCCTCCTGGGGTAGGAGCATAATCT ACATCACTGGGCAGTCACAGGACACTCTATAGCAAGGTTGTAGCGTCCTCTCCAGTGGGGGGAGAAAAGGAACTGTGCCTACCAAAGGTA CTCTCTTGTCAGCAATTTCCATTTCTATACTTTATGGGACACTAGAAACTAAAAGCAACAAATAATCTGATATAAGTCCTTGTATAGTCA TCCTTCAATTCAGTAGCAATATTTTCTGGTCACTACTAACCTGTATTGTATTAAAATGAGACTATTGGAAGGAAATGGTGCTAAAACTAA TAACATCTCTTACCAACCTTTACCCAACTCCTGGGTTGGCAAACAGCTGACCAAACTGCCATCACCTCCCACTTGGAAGTGTATGGCCGA CAGCATGAAATAGCTGAGCCCAGATGTTCCTTCTGCATCCTCCGAATCCCAGGGCTGGGTGTAGGTAGCCGTTGGAGGCCATCGCTACAG GGCACCTATCTGTTATCGCTGCTGTCCTCCCAACAGCTGTCTCCAGTTCTAGTTCCTTGGTTTTCAGGCACAGTGGGGGATGTTCTGCAC CCAGTGGACTTCAAAAGAGTTTTGAAGACTTAATTTTTTGTAAAACAAGTACTTGAGATTTTGGTTTATCCATAATAGAATGTATTTCAT TAGATTCTCTGATTCTATATAAGAATGTGAAAAGATTGATATATTGTTGTTAGAAATAATGTTATTTCTTTCCAATTTTTTTTTTTTTTT TTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAGCCTCTAACTCCCAGGTTCAAGC TATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGATTACAGGCATACACCACCACGCCTGGCTATGTTTTGTATTTTTCGTAGAGATAGGGT TTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCACTTCAGCTTCCCAAAGCACTGGGATTACAGGTGTGA GCCACTGTGCCCGGCAAATTTTTTTACCTTTACAGAAGGTTTTGCTTATTTAATTGTGAGCTCATTTTTCTTTGTTACTTTTGTCCCCCC AGATTTGGGGGACAAAATAAAATTAATCTTTTAAAATGTGTCAGCCATATGTATGGGGCTTCCATTTGGGGTGAGGAGAAAGTTCTGGAA CTAGATAGTGGTCATGGTTATACAACATCATAAATGCAATTACTGCCACTGAATTGTATGTTTTAAAGTGGTTAAAATGTTAAGTTTTAT GTTTTATTACAATTTTTAAATGTGTCAACCAACTTTATAGTACATAAATTATATCTCAGTAAAGCTGTTAAATAAATAAATATAGTAAAA >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_2355nt GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA GAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCA GAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTG TGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTA CCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTG TACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTC AACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGT GCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTC CCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAA CGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTT TGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGC CAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCT GCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGTGCTCGCTGCTGTTGTAGCTACCACCAACTTTCTACTG AAGATGATAACCCAGGGCATAAGAAATGACTTCAGACCCAAGGTTCTGAAAGGGCCCCTCAAGGCCTCGGGTGGCTCCTGCAGAAGTGGC AGAAGAGGCGGGAACTAGGAACCTGGCATCATAGGAAAAGTGCCTTCTCCAAGAAAGAAGGGGCCCCAGGAGGCTGTCTTACTTAGATCA ACCATAAACTACCACAGATGGGTCATTTCTTATATTATTTCAAAATATCTTTGAAGATGAGAATTCATTTGTGTCCTTCATAGACCAAAG TTCTTTGTGTTACCTTTTCCCAAAAGTAAATTCCTTTCCCTTTATTCATTCCTTGTGGAAATAAAATGCAAGCCCTTTATACTTGTCTTA CAGTAATATGGCACATGTAGCTTACTTTTGAGCATCCCAGTGAATAATGTTTGGAACTTTTCTTATTACCTAATAGCATATAGAGAAGAG TGAAGTCAGCTAAAAACAGAAATTTTGAAAAGCCATCTTCAGGAAAATGTAGGCCCAGATGCTTTCCTCCACCTTTTTTGACAGGCTGCC >In-frame_XRCC6_ENST00000359308_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1811nt GCGGGCCGTTATCCATTTGTGTTGTTCGCCAGCTAGGCCTGGCCTCGTCCCGCTTCGCTCGGTCGGTCTCGCGCGCCCCCATAGCCTTGC TAGAGGGTTAGCGTTAGCCTTAAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACC TCGCGTTTGAGGCCCGCCTGCGTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGGCCTGTCTGCGTTTGAGATCTCATTGGG CGTGATTGAGGAATTTGGGGAGGTTTTTGGGCGGTATTGAGGACGAGGGGGTCCGTTAGTCAGCATAGAATCCTGGAGCGGGAATCCCTC ACCGTCTAAATGGCGTCGGGGGCGGGACCTCCGGGATCTGGCTTCCGCGGGCCGCCGCCGGCCCTGAAACGTGAGGGATAGCTGAGATGA GGCAGCTACTGGGATGGCCCCCATGCGCATTTACATGCAGTCCGACTGCCGAGCTTTCGAGGCAGCAGGATTTACCGTCCACATTCCTCA CTACTAACCAAGCTTTTAGAACAGATCTCACAAGAACCTAGAGGTCGGTATTTTTTCGATTTAAATTTGCCTGTTACTGACGTTAACGTC TTTCGCCTAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGGGCGATGAAGAAGCAGAGGAAGAACAAGAAGA GAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGGTTGATGCCTCCAAGGCTATGTTTGAATCTCA GAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTG TGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTA CCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTG TACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTC AACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGT GCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTC CCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGATAA CGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCCTGTGGGAAGGAGGCGTCCGAGGGGTGGGCTT TGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCTCTGACTGGCTGCCAACACTCGTGAAGCTGGC CAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCAGTGAAGGAAGCCCATCCCCCAGAATTGAGCT GCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGTGCTCGCTGCTGTTGTAGCTACCACCAACTTTCTACTG >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000264914_chr5_78265015_-_4819nt AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGG TTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGC ACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCC ATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGG GTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAG AAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGC CTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACA AGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGA ACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCC TGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCT CTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCA GTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTGTCCCAGGAACAGCATGG CTCCAGCAAAGGATGACTCTTCTCTTCCAGAATATTCAGCCTTTAACACATCTGTCCATGCTGCAATTAGACATGGAAATTGGAAACTCC TCACGGGCTACCCAGGCTGTGGTTACTGGTTCCCTCCACCGTCTCAATACAATGTTTCTGAGATACCCTCATCAGACCCACCAACCAAGA CCCTCTGGCTCTTTGATATTGATCGGGACCCTGAAGAAAGACATGACCTGTCCAGAGAATATCCTCACATCGTCACAAAGCTCCTGTCCC GCCTACAGTTCTACCATAAACACTCAGTCCCCGTGTACTTCCCTGCACAGGACCCCCGCTGTGATCCCAAGGCCACTGGGGTGTGGGGCC CTTGGATGTAGGATTTCAGGGAGGCTAGAAAACCTTTCAATTGGAAGTTGGACCTCAGGCCTTTTCTCACGACTCTTGTCTCATTTGTTA TCCCAACCTGGGTTCACTTGGCCCTTCTCTTGCTCTTAAACCACACCGAGGTGTCTAATTTCAACCCCTAATGCATTTAAGAAGCTGATA AAATCTGCAACACTCCTGCTGTTGGCTGGAGCATGTGTCTAGAGGTGGGGGTGGCTGGGTTTATCCCCCTTTCCTAAGCCTTGGGACAGC TGGGAACTTAACTTGAAATAGGAAGTTCTCACTGAATCCTGGAGGCTGGAACAGCTGGCTCTTTTAGACTCACAAGTCAGACGTTCGATT CCCCTCTGCCAATAGCCAGTTTTATTGGAGTGAATCACATTTCTTACGCAAATGAAGGGAGCAGACAGTGATTAATGGTTCTGTTGGCCA AGGCTTCTCCCTGTCGGTGAAGGATCATGTTCAGGCACTCCAAGTGAACCACCCCTCTTGGTTCACCCCTTACTCACTTATCTCATCACA GAGCATAAGGCCCATTTTGTTGTTCAGGTCAACAGCAAAATGCCTGCACCATGACTGTGGCTTTTAAAATAAAGAAATGTGTTTTTATCG TAATTTATTTCCCCCCAGCCATTGCTCACTCTGTCTAGACTTCCTGCCACTTCCAATTCTTCTGTGGCTTTTCCTGCCTTTCCTTTTGAC CTCAGTAGTCCTATCCCTGGGAAGGCCACTTTGCTTCTCTACCTGAGCACCCCTGATTTCTGGAACGCTGCTGAGCCCTGCCTTACTTTT GCCCCTAGGGCTGAAGCTAGAGGCCTCCCCGTAATAGGCGGTGGAGTTGCTCTGTGAGGATGTTCATGGTAGACACTAAGAGGGCTGGGT GGGAGATGCTTGGCTCTGTGGCATCTGTTCAGCGAGGCTTTTCCTATATTGCATGGAGTTAGTCATTGTGATTGTAGCTTTATTTCATAA TATATTAAGACTTGCACTGCTATTTACTAGCAGTGAGAAGAAACCTCAGGAAAGGATATGAAAAAGCAAGTGGCCAGTGTCTGGGATACT GGGCCTTGGTAAAGCAGAGGAGGGCACACCCACAGTCCTCTTATTCTCTGTTTTACTGCTTGTTTTGAGGTTCTGGGGTCTGGCAAAGAG GATGCAGTTTGACACCTGCAGCCCTTTCTCAATCCCACTAATGTCTTACTAATGTGGAACAGTCCATATTAGCTCCAGAGAGTGTCAAAC CCAGAGAAATGTGTGCAAAAATGATACTCTTTTCTGCATTAGCCCCACCATTGTGTTCACCAATGCTTGGAACACTGCCTGAAGGCACTC ATTTTTTAATTTTTATTTTATTTTTAATTTTTTATATCTTTATGAGACGATCTCACTCTGTCACCAGGTTGGAGTACAGTGGTACAATCA CAACTCACCGTAGCCTCAAACTCCTGGGCTCAAGTGATTCTCCCACCTCAGGCACCCAAATAGCTGGAACTACAGGCATATACCGCCACA CCCAGCTAATTTTATTTTTTGAAAAGACAAGGTTCCCTATGTTGCCCAGCTGGTCTTAAACTCCTGGGCTCCAGCAATTATCCCAGCTTG GGCTCCAAAAGTGCTGGGATTACAGGCATGAGTCACCATGCCTGGCCTCATTTTTTAAAACAAATGAATAAATGGACAAATGAGTAAATG AGAAAGTCTCACACCATGAAAGATGCTAGTCCAATGAGCTGAATACAGAGGTAATATAAATGTCTTCCAGCTGTTGCTTTTCTGTTCTCA AGCTGCCCCTCCTGGGGTAGGAGCATAATCTACATCACTGGGCAGTCACAGGACACTCTATAGCAAGGTTGTAGCGTCCTCTCCAGTGGG GGGAGAAAAGGAACTGTGCCTACCAAAGGTACTCTCTTGTCAGCAATTTCCATTTCTATACTTTATGGGACACTAGAAACTAAAAGCAAC AAATAATCTGATATAAGTCCTTGTATAGTCATCCTTCAATTCAGTAGCAATATTTTCTGGTCACTACTAACCTGTATTGTATTAAAATGA GACTATTGGAAGGAAATGGTGCTAAAACTAATAACATCTCTTACCAACCTTTACCCAACTCCTGGGTTGGCAAACAGCTGACCAAACTGC CATCACCTCCCACTTGGAAGTGTATGGCCGACAGCATGAAATAGCTGAGCCCAGATGTTCCTTCTGCATCCTCCGAATCCCAGGGCTGGG TGTAGGTAGCCGTTGGAGGCCATCGCTACAGGGCACCTATCTGTTATCGCTGCTGTCCTCCCAACAGCTGTCTCCAGTTCTAGTTCCTTG GTTTTCAGGCACAGTGGGGGATGTTCTGCACCCAGTGGACTTCAAAAGAGTTTTGAAGACTTAATTTTTTGTAAAACAAGTACTTGAGAT TTTGGTTTATCCATAATAGAATGTATTTCATTAGATTCTCTGATTCTATATAAGAATGTGAAAAGATTGATATATTGTTGTTAGAAATAA TGTTATTTCTTTCCAATTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTCGGC TCACTGCAGCCTCTAACTCCCAGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGATTACAGGCATACACCACCACGCCTGG CTATGTTTTGTATTTTTCGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCACTTCA GCTTCCCAAAGCACTGGGATTACAGGTGTGAGCCACTGTGCCCGGCAAATTTTTTTACCTTTACAGAAGGTTTTGCTTATTTAATTGTGA GCTCATTTTTCTTTGTTACTTTTGTCCCCCCAGATTTGGGGGACAAAATAAAATTAATCTTTTAAAATGTGTCAGCCATATGTATGGGGC TTCCATTTGGGGTGAGGAGAAAGTTCTGGAACTAGATAGTGGTCATGGTTATACAACATCATAAATGCAATTACTGCCACTGAATTGTAT GTTTTAAAGTGGTTAAAATGTTAAGTTTTATGTTTTATTACAATTTTTAAATGTGTCAACCAACTTTATAGTACATAAATTATATCTCAG >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000396151_chr5_78265015_-_1846nt AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGG TTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGC ACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCC ATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGG GTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAG AAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGC CTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACA AGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGA ACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCC TGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCT CTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCA GTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGTGCTCGC TGCTGTTGTAGCTACCACCAACTTTCTACTGAAGATGATAACCCAGGGCATAAGAAATGACTTCAGACCCAAGGTTCTGAAAGGGCCCCT CAAGGCCTCGGGTGGCTCCTGCAGAAGTGGCAGAAGAGGCGGGAACTAGGAACCTGGCATCATAGGAAAAGTGCCTTCTCCAAGAAAGAA GGGGCCCCAGGAGGCTGTCTTACTTAGATCAACCATAAACTACCACAGATGGGTCATTTCTTATATTATTTCAAAATATCTTTGAAGATG AGAATTCATTTGTGTCCTTCATAGACCAAAGTTCTTTGTGTTACCTTTTCCCAAAAGTAAATTCCTTTCCCTTTATTCATTCCTTGTGGA AATAAAATGCAAGCCCTTTATACTTGTCTTACAGTAATATGGCACATGTAGCTTACTTTTGAGCATCCCAGTGAATAATGTTTGGAACTT TTCTTATTACCTAATAGCATATAGAGAAGAGTGAAGTCAGCTAAAAACAGAAATTTTGAAAAGCCATCTTCAGGAAAATGTAGGCCCAGA >In-frame_XRCC6_ENST00000405878_chr22_42024234_+_ARSB_ENST00000565165_chr5_78265015_-_1302nt AAGTGTGCGAATCCGAGGAGCAGCGACAGACTCGAGACCACGCTCCTTCCTCGGGAAGGAGGCGGCACCTCGCGTTTGAGGCCCGCCTGC GTTTGAGGCCCGCCTGCGCTTGCGGCCCGCCTGCGCTTGAGTGAGCAGTAGCCAACATGTCAGGGTGGGAGTCATATTACAAAACCGAGG GCGATGAAGAAGCAGAGGAAGAACAAGAAGAGAACCTTGAAGCAAGTGGAGACTATAAATATTCAGGAAGAGATAGTTTGATTTTTTTGG TTGATGCCTCCAAGGCTATGTTTGAATCTCAGAGTGAAGATGAGTTGACACCTTTTGACATGAGCATCCAGATCCGTACAGGTTTACAGC ACCAAATAATCTGGCCCTGTCAGCCCAGCTGTGTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCC ATATGGTCGGAAAATGGCACCTGGGAATGTACCGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGG GTAGTGAAGATTATTATTCCCATGAACGCTGTACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAG AAGTTGCAACAGGATATAAAAATATGTATTCAACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGC CTCTGTTTCTCTACCTTGCTCTCCAGTCTGTGCATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACA AGAACAGGCATCACTATGCAGGAATGGTGTCCCTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGA ACAACACGGTGTTCATCTTTTCTACAGATAACGGAGGGCAGACTTTGGCAGGGGGTAATAACTGGCCCCTTCGAGGAAGAAAATGGAGCC TGTGGGAAGGAGGCGTCCGAGGGGTGGGCTTTGTGGCAAGCCCCTTGCTGAAGCAGAAGGGCGTGAAGAACCGGGAGCTCATCCACATCT CTGACTGGCTGCCAACACTCGTGAAGCTGGCCAGGGGACACACCAATGGCACAAAGCCTCTGGATGGCTTCGACGTGTGGAAAACCATCA GTGAAGGAAGCCCATCCCCCAGAATTGAGCTGCTGCATAATATTGACCCGAACTTCGTGGACTCTTCACCGTACTGGCCTGAGTGCTCGC |
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FusionGenePPI for XRCC6_ARSB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| XRCC6 | VAV1, NCF4, XRCC5, MRE11A, CBX5, AR, CCNA1, CDK2, TERF2IP, CHEK1, NCOA6, KAT2A, CREBBP, ACD, CDCA5, ARAP1, FMNL1, GAL3ST4, ILVBL, NOTCH1, PGAM1, RBBP4, TBCD, ABCD4, PLGRKT, GSE1, NHP2L1, NIT1, PECAM1, RRAS2, SNTA1, ATP6V1E1, PAEP, PAFAH1B3, RPLP1, SERPINB9, YWHAZ, XRCC6BP1, CLU, PRKDC, RPA2, TERT, DNTT, HOXC4, HOXD4, DLX2, POU2F2, POU2F1, TAL1, TERF2, WRN, BIN1, PTTG1, CD40, PCNA, HSF1, ABL1, DHX9, FCHSD1, SIRT6, NR1H4, CHD1L, TP53, BARD1, ESR1, PARP1, SIRT3, MGMT, PDX1, SRRM2, MSX2, RUNX2, NAA15, H2AFX, PHF1, XRCC4, LIG4, KAT2B, EP300, ATXN3, ILF2, THRA, THRB, BIRC5, CHAF1A, HIST1H3A, HIST1H3E, H3F3A, BAZ1A, MYC, USF1, HDAC5, UBE3A, RBM39, MDM2, BAX, DDB2, PSMA3, CMTM6, RPS10, RASA1, EFNA1, TAC1, PDK1, CENPU, KIAA0408, EID1, VBP1, SDHC, PDPK1, ANXA1, BTG1, PNRC2, QRSL1, RGS2, MAP4K2, HERPUD1, SEP15, SPARC, COIL, LIG3, HOXB7, YY1, RNF146, SMARCAD1, ORC3, ORC2, ORC6, ORC4, TCF7L2, NDRG1, HDGF, ILF3, MSH6, MSH2, CBX1, CBX3, CEBPA, ARRB2, SIRT7, HNRNPA1, CFLAR, HDAC6, ERG, ISG15, TONSL, CUL5, COPS5, CAND1, HTT, CLTC, TADA3, CCT3, KCND3, ARHGAP5, EEF2, SDHA, HSPA5, KIF23, PGR, XRCC6, BRCA1, ECT2, PAXIP1, TP53BP1, NCL, CSNK2A1, SMURF1, PNKP, FN1, VCAM1, GZMA, GZMB, SMAD7, SKIL, SMAD3, ZNF512B, ITGA4, PPID, IGSF8, ICAM1, HMGA1, HMGA2, LMNA, CTBP2, COPB1, ADCY7, EPS8, MAP2K5, CAPN11, SERPINA2, TARDBP, PARK2, PRPF40A, WBP4, PIN1, CTNNA1, CUL2, CSDE1, FARSB, GANAB, GART, IMPDH1, JUP, DPYSL3, PLOD2, RANBP3, SAMHD1, SET, ST13, SUPT5H, SWAP70, ATP6V1B2, HYOU1, RPSA, NARS, RPA1, RPA3, ATRX, EMD, ELF3, EHF, ENO1, SHMT2, MOV10, NXF1, PPARG, CUL7, OBSL1, CCDC8, EED, SUMO2, MAST3, WDR76, APLF, PHRF1, NTRK1, DYNC1LI1, GTF2I, HNRNPK, NAE1, PDIA3, RFC1, TKT, TMOD3, SCARNA22, CSNK1A1, DNM2, BAG2, ANKRD28, POT1, TINF2, TNRC18, CCDC57, C9orf142, BANP, CRY2, MACROD1, MCM2, NF2, SNW1, TFAP2A, UHRF2, U2AF2, RC3H1, FOXL2, NFATC1, NFATC2, AHSA1, RNF126, PARP2, XPC, SUPT16H, XRCC1, H2AFY, CDK5RAP1, SSRP1, SPTA1, COX15, DLD, DLST, DNM1L, HSD17B10, SOD1, VDAC1, TRIM25, UBE2S, YAP1 | ARSB | ELAVL1, ESR1, SUSD4, PLAUR, PTPRK, SIAE, NAAA, ERP29, DEFA1, INSL5, AVP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000359308 | + | 2 | 12 | 550_609 | 65 | 610 | DEAF1 |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000360079 | + | 3 | 13 | 550_609 | 65 | 610 | DEAF1 |
| Hgene | XRCC6 | chr22:42024234 | chr5:78265015 | ENST00000405878 | + | 3 | 13 | 550_609 | 65 | 610 | DEAF1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for XRCC6_ARSB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for XRCC6_ARSB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ARSB | C0026709 | Mucopolysaccharidosis VI | 11 | CTD_human;UNIPROT |
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