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Fusion gene ID: 42164 |
FusionGeneSummary for XPC_RCOR1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: XPC_RCOR1 | Fusion gene ID: 42164 | Hgene | Tgene | Gene symbol | XPC | RCOR1 | Gene ID | 7508 | 23186 |
| Gene name | XPC complex subunit, DNA damage recognition and repair factor | REST corepressor 1 | |
| Synonyms | RAD4|XP3|XPCC|p125 | COREST|RCOR | |
| Cytomap | 3p25.1 | 14q32.31-q32.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA repair protein complementing XP-C cellsmutant xeroderma pigmentosum group Cxeroderma pigmentosum, complementation group C | REST corepressor 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q01831 | Q9UKL0 | |
| Ensembl transtripts involved in fusion gene | ENST00000285021, ENST00000449060, | ENST00000262241, ENST00000570597, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 6 X 7 X 4=168 |
| # samples | 3 | 7 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: XPC [Title/Abstract] AND RCOR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | XPC | GO:0000715 | nucleotide-excision repair, DNA damage recognition | 10873465|19941824 |
| Hgene | XPC | GO:0006289 | nucleotide-excision repair | 8168482|9734359 |
| Hgene | XPC | GO:0070914 | UV-damage excision repair | 8077226 |
| Tgene | RCOR1 | GO:0045892 | negative regulation of transcription, DNA-templated | 10449787 |
| Tgene | RCOR1 | GO:0070933 | histone H4 deacetylation | 17555596 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A06Q-01A | XPC | chr3 | 14209757 | - | RCOR1 | chr14 | 103177272 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000285021 | ENST00000262241 | XPC | chr3 | 14209757 | - | RCOR1 | chr14 | 103177272 | + |
| In-frame | ENST00000285021 | ENST00000570597 | XPC | chr3 | 14209757 | - | RCOR1 | chr14 | 103177272 | + |
| In-frame | ENST00000449060 | ENST00000262241 | XPC | chr3 | 14209757 | - | RCOR1 | chr14 | 103177272 | + |
| In-frame | ENST00000449060 | ENST00000570597 | XPC | chr3 | 14209757 | - | RCOR1 | chr14 | 103177272 | + |
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FusionProtFeatures for XPC_RCOR1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| XPC | RCOR1 |
| Involved in global genome nucleotide excision repair(GG-NER) by acting as damage sensing and DNA-binding factorcomponent of the XPC complex. Has only a low DNA repair activityby itself which is stimulated by RAD23B and RAD23A. Has apreference to bind DNA containing a short single-stranded segmentbut not to damaged oligonucleotides. This feature is proposed tobe related to a dynamic sensor function: XPC can rapidly screenduplex DNA for non-hydrogen-bonded bases by forming a transientnucleoprotein intermediate complex which matures into a stablerecognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the firstfactor bound at the sites of DNA damage and together with othercore recognition factors, XPA, RPA and the TFIIH complex, is partof the pre-incision (or initial recognition) complex. The XPCcomplex recognizes a wide spectrum of damaged DNA characterized bydistortions of the DNA helix such as single-stranded loops,mismatched bubbles or single-stranded overhangs. The orientationof XPC complex binding appears to be crucial for inducing aproductive NER. XPC complex is proposed to recognize and tointeract with unpaired bases on the undamaged DNA strand which isfollowed by recruitment of the TFIIH complex and subsequentscanning for lesions in the opposite strand in a 5'-to-3'direction by the NER machinery. Cyclobutane pyrimidine dimers(CPDs) which are formed upon UV-induced DNA damage esacpedetection by the XPC complex due to a low degree of structuralperurbation. Instead they are detected by the UV-DDB complex whichin turn recruits and cooperates with the XPC complex in therespective DNA repair. In vitro, the XPC:RAD23B dimer issufficient to initiate NER; it preferentially binds to cisplatinand UV-damaged double-stranded DNA and also binds to a variety ofchemically and structurally diverse DNA adducts. XPC:RAD23Bcontacts DNA both 5' and 3' of a cisplatin lesion with apreference for the 5' side. XPC:RAD23B induces a bend in DNA uponbinding. XPC:RAD23B stimulates the activity of DNA glycosylasesTDG and SMUG1. | Essential component of the BHC complex, a corepressorcomplex that represses transcription of neuron-specific genes innon-neuronal cells. The BHC complex is recruited at RE1/NRSE sitesby REST and acts by deacetylating and demethylating specific siteson histones, thereby acting as a chromatin modifier. In the BHCcomplex, it serves as a molecular beacon for the recruitment ofmolecular machinery, including MeCP2 and SUV39H1, that imposessilencing across a chromosomal interval. Plays a central role indemethylation of Lys-4 of histone H3 by promoting demethylaseactivity of KDM1A on core histones and nucleosomal substrates. Italso protects KDM1A from the proteasome. Component of aRCOR/GFI/KDM1A/HDAC complex that suppresses, via histonedeacetylase (HDAC) recruitment, a number of genes implicated inmultilineage blood cell development and controls hematopoieticdifferentiation. {ECO:0000269|PubMed:11171972,ECO:0000269|PubMed:11516394, ECO:0000269|PubMed:12032298,ECO:0000269|PubMed:12399542, ECO:0000269|PubMed:12493763,ECO:0000269|PubMed:16079794, ECO:0000269|PubMed:16140033}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 124_130 | 178 | 941 | Compositional bias | Note=Poly-Glu |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 30_177 | 178 | 941 | Compositional bias | Note=Glu-rich (acidic) |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 30_34 | 178 | 941 | Compositional bias | Note=Poly-Glu |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 124_130 | 141 | 904 | Compositional bias | Note=Poly-Glu |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 30_34 | 141 | 904 | Compositional bias | Note=Poly-Glu |
| Tgene | >RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 334_369 | 256 | 483 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 381_432 | 256 | 483 | Domain | SANT 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 359_395 | 178 | 941 | Compositional bias | Note=Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 408_431 | 178 | 941 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 432_461 | 178 | 941 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 466_493 | 178 | 941 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 501_507 | 178 | 941 | Compositional bias | Note=Poly-Ser |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 30_177 | 141 | 904 | Compositional bias | Note=Glu-rich (acidic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 359_395 | 141 | 904 | Compositional bias | Note=Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 408_431 | 141 | 904 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 432_461 | 141 | 904 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 466_493 | 141 | 904 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 501_507 | 141 | 904 | Compositional bias | Note=Poly-Ser |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 390_395 | 178 | 941 | Motif | Nuclear localization signal |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 390_395 | 141 | 904 | Motif | Nuclear localization signal |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 607_741 | 178 | 941 | Region | Note=DNA-binding%3B preference for heteroduplex DNA |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 607_766 | 178 | 941 | Region | Note=Minimal sensor domain involved in damage recognition |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 767_831 | 178 | 941 | Region | Note=DNA-binding%3B preference for single stranded DNA%3B required for formation of stable nucleoprotein complex |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 607_741 | 141 | 904 | Region | Note=DNA-binding%3B preference for heteroduplex DNA |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 607_766 | 141 | 904 | Region | Note=Minimal sensor domain involved in damage recognition |
| Hgene | >XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 767_831 | 141 | 904 | Region | Note=DNA-binding%3B preference for single stranded DNA%3B required for formation of stable nucleoprotein complex |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 244_273 | 256 | 483 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 21_77 | 256 | 483 | Compositional bias | Note=Ala-rich |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 103_189 | 256 | 483 | Domain | ELM2 |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 190_241 | 256 | 483 | Domain | SANT 1 |
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FusionGeneSequence for XPC_RCOR1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_405aa MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKD EALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSE DELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQ IQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWE >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_405aa MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKD EALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSE DELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQ IQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWE >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_368aa MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKD EALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEAKTRERSEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKK EKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTT EEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLD >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_368aa MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKD EALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEAKTRERSEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKK EKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTT EEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_1215nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGTTGAAGAACTTAGTGAGCCTGTGCTGGGTGACGTGAGAGAAAGT ACAGCCTTCTCTCGATCTCTTCTGCCTGTGAAGCCAGTGGAGATAGAGATTGAAACGCCAGAGCAGGCGAAGACAAGAGAAAGAAGCGAG GATGAACTGGAAGAGGCAAATGGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAG ACAGTTCCTCAGGTCAAAAAAGAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAA GAAGATGTGGAGGCTGTTTCTGCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAG ATCCAGAATATTAAACAGACAAACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAA TGTAATGCACGTTGGACTACAGAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTG ATTGGGAACAAATCAGTGGTACAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAG GCAGAACATGGTAAAGAAGAGACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAA >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_1215nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGTTGAAGAACTTAGTGAGCCTGTGCTGGGTGACGTGAGAGAAAGT ACAGCCTTCTCTCGATCTCTTCTGCCTGTGAAGCCAGTGGAGATAGAGATTGAAACGCCAGAGCAGGCGAAGACAAGAGAAAGAAGCGAG GATGAACTGGAAGAGGCAAATGGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAG ACAGTTCCTCAGGTCAAAAAAGAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAA GAAGATGTGGAGGCTGTTTCTGCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAG ATCCAGAATATTAAACAGACAAACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAA TGTAATGCACGTTGGACTACAGAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTG ATTGGGAACAAATCAGTGGTACAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAG GCAGAACATGGTAAAGAAGAGACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAA >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_1104nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAAT GGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAA GAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCT GCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACA AACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACA GAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTA CAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAG ACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGAT >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_1104nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAAT GGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAA GAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCT GCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACA AACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACA GAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTA CAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAG ACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_5500nt ATACACCGGAAATAGAGAGAAACCTGTTGTGCTCTTTCCTGCTTCCCGCAGTTTTTTAGTGGCCACGGGTATGGGGTGGAGCTTCCTTTA GGGGCGTGACTAGGCCTCCAACGAAGGGGCGTGGCCAAGCGCACCGCCTCGGGGCGGGGCCGGCGTTCTAGCGCATCGCGGCCGGGTGCG TCACTCGCGAAGTGGAATTTGCCCAGACAAGCAACATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCC AGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAGGAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCT CCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGCAGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGA CTGTTAAATCTGAAAACCTCAAGGTTATAAAGGATGAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGG CACACCATCTGAAGAGAGGGGCTACCATGAATGAAGACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGTTGAAGAAC TTAGTGAGCCTGTGCTGGGTGACGTGAGAGAAAGTACAGCCTTCTCTCGATCTCTTCTGCCTGTGAAGCCAGTGGAGATAGAGATTGAAA CGCCAGAGCAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAATGGAAACAATCCCATTGACATTGAGGTTGATCAAA ACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAAGAAAAACATAGCACACAAGCTAAAAATAGAGCAA AAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCTGCCAATGCCACTGCTGCTACCACGGTGCTGAGAC AACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACAAACAGTGCTCTCAAAGAAAAACTTGATGGTGGAA TAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACAGAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGA AATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTACAAGTGAAAAACTTTTTTGTAAATTATCGACGCC GCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAGACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGT CCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGATGTCAGATATGCATCTGCCTCCTGAGAAACTGGTG GCTTTGAACACTTGGTGTGGACTACTGTGTTATCCGGGATATCAGGTATTATGAGACATCACCTAGCCATCTGCATCACATCTCTCTGGA CAAGCAGCTATTACCAAAAAAGGCATATACTTCCAGTCCTGTGCTCCATCTGCCTTAATTCTTTGCTCGTTCCTCCATGTTGGCGCCACT TCCCAGAGAGCTCCACTGCATCTCACACTCTGCCCACGTGCTGGGGAAGTCTCACGGCCTGCACATCTCTTGTGACTCTGGGAACCGCCT CTCCCGCCGGAGCCCCCGAGCCCCACCAATGGCAGCTCTTCCCAGTCAGCAGCTTCAGAGCAGGCAGTCTCCTTGGAAGGCCCGACTCTG TTCCTGCATGGCCTGCAGTTTCTACTTTGTGCATAGAGTCATTTTCAGAGTCACCGCGACCCTGTTGGCCTTCTAGAAAGTTTCTTTTGT TCTTTTCTGAGACAACCACCTAAGTGATAATACGCTTTTTTGGAAACTAATATATATTGCCAGACTGCATCATAACCTTTATCATGCCAA GCATCCTGATGCAACTCACATTTCCCTAAACATGGGGTACAGTTATGATTTATAAATTGAGTTGGCTTAAATCTCCCTCTTCTCCCTTCC CAAGTGTTACAAAGATCATTTACTGCAACTGTCGTTGGACACTGTAGCTTAAAGGGAACGTGGACCTCAATGCTTTCTGCCTTCAACTTT TCAGCATTGTGACCCCAGGGTGGTTGCCACCCCATCTTTTCCTGACCCCCCCCACCCCCCCACCTCCAAGAGGTTCGGCCCACATCACTG TACCTGGTGCTTGTAAATTTGGAATTGGTGCCTTCTCCTTTTGGCAACCATGGTTATCAATCCTTTTTCTGTTTTAGTGTCTTATTTCTT CTTTCAAGTTATTTGCTAGCCAAAGATGACATCACTGAGATTAGGAGACAGGGGAGAGCTTGCTGCAGATTCTGACAGTGCAGATTTTAA ATGTCAGGATATTAGAATAGCTGGCGCTGGTTTATGAAAGCTGCGCGTTGTTCCGCGTTCTCTCGGTGTGCCTGGCCTTTTATGTGGCAC TCTGTATGTCAGTTTGTGTCCTTCATGTGCTGATGTGATTACACAAACACCATGCACTCTCTTTTCATATCAGAGTACAGGACAGAGAAG TGATCAATGTATTGGTCTAGTGAGACTGAGATGAAAAGAAATAACCTACAGAGTGGTCTGTAATGCCTTTTGGTTGGACTGGGAACAAGT AAAAATTTCTAATAAACATTTTGAGACTTCCAGAATCACTTTTGTTATCTTATCAGACCATGGGCCTGCTGAGGGTTGAGCAGACAGCCT GCATTCTAACATACCCTGTTCCCACCCCACGGCCATTCAGACTGCACTCAATACGCTGAAGTCGCTTTTGTTGTTGTTGTTGTTGTTTGC ATCATTTGGATTTTTTTCCTGCTTTCAATACCAAAAAAATGCAGATGCTTTAAGGCCTAAACAGAATTCTGAAGAATTTAAAATATGCAA TTAAAGTTTGATATGTTTTGTCTCCCAAGCACCTTGTTTTTTGTTGTTGTTGTTGTTGTTGAAGTCAGCTGATTTTCTCTTTAGAAAGAG GGTCAGCTAGAAACCTAGGTTTTTTGGAATTGTAAATTTTTTTTTAGTATAGTCTGGAGAGAAAGGTCATTCAAAAGGAAAGTACAATGG GACTTGCTGCCCTTCATCATCTCGTTCCCGTGCCAGGTGTGTGTTGGTCACGTAAAAGCCTGGGAAGCATCAGAGGAGTCCCGGATTGCT GCTGCTACCTGGAGACAGGGTTAGCAAAATAACACTAGTGATGAGGGAGAGGCTTCTTTTCACCATAAGCCTGCTGTGTACACCGAGGGC GGCAGGAGAAGCATGGGAAGGAGTCAGCCTAAGTTTGCACATTGCATAAAGGGTACACTAAGGTATGAGCTGAAGCTTTAGGTTCTCCGT GCTTCCCTCAAGACCTCCTTCTTGCTAACAGAAGCAGTAGGCAATTGCTGCAGTGCGTTTCTCACCCTGCCAATAGGTCTGTCTGTATCT CTGTTAAGGAAAATAGCCTGGTCCCTCCTGGCAGTGCTTGGAAGCTTGATGCTAATTTTTATATAGCGTGGCAAACTGACCAGCAGTGCC AGGCCTTGATCTGTATTCTGCACTATCCCTTTACTTGGTTCCTGGCACTGAATGGTCTCCAGCCCTGAAGAATCACGTGTGATCACAGCA GCTGACCTGGGCTTTCTCCCCGAGAGGAAGGGGCATGTCATTTTTATTTGACAGAGGGAAAATGGGAGCTGTCCTTGACTGCCTTTGTTG TGCTTTCCCGCGTAAGATAGCACTGTGTTTTAAACTGTTGCATTACACTGTCTTTGCAATGATGTAAATGTAAGAAATCACTTAGCTTTA AAAGCGCAGTGGTTTGATCTTATTTATATGAAGACTTTTTAACATATCAAGAATTAGGTGCATTGGCAGGTAGGGTTTGGGGTGTGATAA CTGCTTCAGATGGAATGTTCACTTAAGCTTTGTCTTCTTAAAAATTATCAATGTGAATGTCATAATTATATATATTTTTGTGGAAAATTT TCTCCTAAGTATAAGTTATTGTGCAAAATATAGTGTCATTGATGCAAATAATAGTTTAACTTTTAGTTTAGAACTCCTAAAAGATATAAA TTGTATTGCATATGCATTAAAAGTTTGTTTTATTTAATTTTATGTAGATGTGTGAAGTGTTAGGTAAAATTTTTTTCACTTATCCATTTA AACACCTTGTTACTTGAATATTGTGTTGACTGGTCTGCAACAGTGATCCATTCTGTAATATAGCTCTTTTAACTGGGAAGGAACCACACC CCAGTTGTGCCGATTACATTAGTGTTGGCACACAGTCGGGTGCTAGTGTAACACAAATGCCGCGTTGTCTGGGTGTACAGTGTTTGTGGA GACGCCACTTCCTCAAAATGGTTTTTGATTGTTTTTAACCTATAAGACGTTCTGATGCTCACAAACCTCTATTCAACACACAAAACAAAC ATGAAAAGGTAGTTAGTTGGGTTGTAACAGCTTACTGGGGTGGACTCATAAAACAGTGGCTTTCTGTTCATCTAAAGTTTCCTCAGATAC CACAGACCACTGTTAAGTGTGCTCATTGTCACTTTAAATTTCAACGATACCCTATTTTTGTCATTCTAAATATCAGATGTACTATTGGTA TAATTGCACACCAAAAATAAGCCAAACAGTGCATTACGCTAACTGGATCCCTGCTTTTATGTGAGCTAAGGAAAGATGGAGCCAACTCCA ACGAGGGCCTCTTTTTCTCTCTTGTCTAGCCTGTTTCTAAACCGAATGATCCAGGATTCAAGCTTCTATTGTCAAGTGAAACTTTCCTCA GATGGACTCCAGGTAGCCAGGTCACCTAAACCTAGTGGTCCTGTGCGATGCTCTTTCTGCCAGTCCCTGAATCTCTGCAGCTTCTCTTAC CTGTCTTACCTGTAGTAAAGCACAATTGCAGTGGCGTCGCATTCAGAAGAAGGGAAGGTCAGCAGAGGCTATGCATGTTGTGTGATGATG AGTGTTTACAGCCACCTTCTCCTAAAACGAAATTTATACCGGGGTGGATAGTATTCCATTAGGTAGACTTATCGACTTTGCTAAGTGCTT TTTAGACAGCTTAAAAAATTTTCAAGATTTTAAAAGATGTATAAGGTTAAGTTTGCAAATATAATGGAAATGCTGTATATCTTTTGAAGT GATGAAATCCACGTTGGAATTTTAAAGAAAATATGTTGTAATAATGCTGTTGTAAGTAATATTTTAATGTCTCTTTGCCTGTTTTCTATT TCAGCACATTCATTGTGGTGAATGTTCATAGCATTATAACTGCTTAGCCATTGAATGATAACATTTGTTAGTGGAAATTGGAAAATTTAT TTGTGAAATTCTGCAGAATTCATTTTTCTATTTCCAATATTTGCTGAGGTTAAATAAAAATTTTCAAGCCATTGATGTAATAAAATATGA >In-frame_XPC_ENST00000285021_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_5499nt ATACACCGGAAATAGAGAGAAACCTGTTGTGCTCTTTCCTGCTTCCCGCAGTTTTTTAGTGGCCACGGGTATGGGGTGGAGCTTCCTTTA GGGGCGTGACTAGGCCTCCAACGAAGGGGCGTGGCCAAGCGCACCGCCTCGGGGCGGGGCCGGCGTTCTAGCGCATCGCGGCCGGGTGCG TCACTCGCGAAGTGGAATTTGCCCAGACAAGCAACATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCC AGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAGGAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCT CCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGCAGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGA CTGTTAAATCTGAAAACCTCAAGGTTATAAAGGATGAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGG CACACCATCTGAAGAGAGGGGCTACCATGAATGAAGACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGTTGAAGAAC TTAGTGAGCCTGTGCTGGGTGACGTGAGAGAAAGTACAGCCTTCTCTCGATCTCTTCTGCCTGTGAAGCCAGTGGAGATAGAGATTGAAA CGCCAGAGCAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAATGGAAACAATCCCATTGACATTGAGGTTGATCAAA ACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAAGAAAAACATAGCACACAAGCTAAAAATAGAGCAA AAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCTGCCAATGCCACTGCTGCTACCACGGTGCTGAGAC AACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACAAACAGTGCTCTCAAAGAAAAACTTGATGGTGGAA TAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACAGAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGA AATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTACAAGTGAAAAACTTTTTTGTAAATTATCGACGCC GCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAGACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGT CCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGATGTCAGATATGCATCTGCCTCCTGAGAAACTGGTG GCTTTGAACACTTGGTGTGGACTACTGTGTTATCCGGGATATCAGGTATTATGAGACATCACCTAGCCATCTGCATCACATCTCTCTGGA CAAGCAGCTATTACCAAAAAAGGCATATACTTCCAGTCCTGTGCTCCATCTGCCTTAATTCTTTGCTCGTTCCTCCATGTTGGCGCCACT TCCCAGAGAGCTCCACTGCATCTCACACTCTGCCCACGTGCTGGGGAAGTCTCACGGCCTGCACATCTCTTGTGACTCTGGGAACCGCCT CTCCCGCCGGAGCCCCCGAGCCCCACCAATGGCAGCTCTTCCCAGTCAGCAGCTTCAGAGCAGGCAGTCTCCTTGGAAGGCCCGACTCTG TTCCTGCATGGCCTGCAGTTTCTACTTTGTGCATAGAGTCATTTTCAGAGTCACCGCGACCCTGTTGGCCTTCTAGAAAGTTTCTTTTGT TCTTTTCTGAGACAACCACCTAAGTGATAATACGCTTTTTTGGAAACTAATATATATTGCCAGACTGCATCATAACCTTTATCATGCCAA GCATCCTGATGCAACTCACATTTCCCTAAACATGGGGTACAGTTATGATTTATAAATTGAGTTGGCTTAAATCTCCCTCTTCTCCCTTCC CAAGTGTTACAAAGATCATTTACTGCAACTGTCGTTGGACACTGTAGCTTAAAGGGAACGTGGACCTCAATGCTTTCTGCCTTCAACTTT TCAGCATTGTGACCCCAGGGTGGTTGCCACCCCATCTTTTCCTGACCCCCCCCACCCCCCCACCTCCAAGAGGTTCGGCCCACATCACTG TACCTGGTGCTTGTAAATTTGGAATTGGTGCCTTCTCCTTTTGGCAACCATGGTTATCAATCCTTTTTCTGTTTTAGTGTCTTATTTCTT CTTTCAAGTTATTTGCTAGCCAAAGATGACATCACTGAGATTAGGAGACAGGGGAGAGCTTGCTGCAGATTCTGACAGTGCAGATTTTAA ATGTCAGGATATTAGAATAGCTGGCGCTGGTTTATGAAAGCTGCGCGTTGTTCCGCGTTCTCTCGGTGTGCCTGGCCTTTTATGTGGCAC TCTGTATGTCAGTTTGTGTCCTTCATGTGCTGATGTGATTACACAAACACCATGCACTCTCTTTTCATATCAGAGTACAGGACAGAGAAG TGATCAATGTATTGGTCTAGTGAGACTGAGATGAAAAGAAATAACCTACAGAGTGGTCTGTAATGCCTTTTGGTTGGACTGGGAACAAGT AAAAATTTCTAATAAACATTTTGAGACTTCCAGAATCACTTTTGTTATCTTATCAGACCATGGGCCTGCTGAGGGTTGAGCAGACAGCCT GCATTCTAACATACCCTGTTCCCACCCCACGGCCATTCAGACTGCACTCAATACGCTGAAGTCGCTTTTGTTGTTGTTGTTGTTGTTTGC ATCATTTGGATTTTTTTCCTGCTTTCAATACCAAAAAAATGCAGATGCTTTAAGGCCTAAACAGAATTCTGAAGAATTTAAAATATGCAA TTAAAGTTTGATATGTTTTGTCTCCCAAGCACCTTGTTTTTTGTTGTTGTTGTTGTTGTTGAAGTCAGCTGATTTTCTCTTTAGAAAGAG GGTCAGCTAGAAACCTAGGTTTTTTGGAATTGTAAATTTTTTTTTAGTATAGTCTGGAGAGAAAGGTCATTCAAAAGGAAAGTACAATGG GACTTGCTGCCCTTCATCATCTCGTTCCCGTGCCAGGTGTGTGTTGGTCACGTAAAAGCCTGGGAAGCATCAGAGGAGTCCCGGATTGCT GCTGCTACCTGGAGACAGGGTTAGCAAAATAACACTAGTGATGAGGGAGAGGCTTCTTTTCACCATAAGCCTGCTGTGTACACCGAGGGC GGCAGGAGAAGCATGGGAAGGAGTCAGCCTAAGTTTGCACATTGCATAAAGGGTACACTAAGGTATGAGCTGAAGCTTTAGGTTCTCCGT GCTTCCCTCAAGACCTCCTTCTTGCTAACAGAAGCAGTAGGCAATTGCTGCAGTGCGTTTCTCACCCTGCCAATAGGTCTGTCTGTATCT CTGTTAAGGAAAATAGCCTGGTCCCTCCTGGCAGTGCTTGGAAGCTTGATGCTAATTTTTATATAGCGTGGCAAACTGACCAGCAGTGCC AGGCCTTGATCTGTATTCTGCACTATCCCTTTACTTGGTTCCTGGCACTGAATGGTCTCCAGCCCTGAAGAATCACGTGTGATCACAGCA GCTGACCTGGGCTTTCTCCCCGAGAGGAAGGGGCATGTCATTTTTATTTGACAGAGGGAAAATGGGAGCTGTCCTTGACTGCCTTTGTTG TGCTTTCCCGCGTAAGATAGCACTGTGTTTTAAACTGTTGCATTACACTGTCTTTGCAATGATGTAAATGTAAGAAATCACTTAGCTTTA AAAGCGCAGTGGTTTGATCTTATTTATATGAAGACTTTTTAACATATCAAGAATTAGGTGCATTGGCAGGTAGGGTTTGGGGTGTGATAA CTGCTTCAGATGGAATGTTCACTTAAGCTTTGTCTTCTTAAAAATTATCAATGTGAATGTCATAATTATATATATTTTTGTGGAAAATTT TCTCCTAAGTATAAGTTATTGTGCAAAATATAGTGTCATTGATGCAAATAATAGTTTAACTTTTAGTTTAGAACTCCTAAAAGATATAAA TTGTATTGCATATGCATTAAAAGTTTGTTTTATTTAATTTTATGTAGATGTGTGAAGTGTTAGGTAAAATTTTTTTCACTTATCCATTTA AACACCTTGTTACTTGAATATTGTGTTGACTGGTCTGCAACAGTGATCCATTCTGTAATATAGCTCTTTTAACTGGGAAGGAACCACACC CCAGTTGTGCCGATTACATTAGTGTTGGCACACAGTCGGGTGCTAGTGTAACACAAATGCCGCGTTGTCTGGGTGTACAGTGTTTGTGGA GACGCCACTTCCTCAAAATGGTTTTTGATTGTTTTTAACCTATAAGACGTTCTGATGCTCACAAACCTCTATTCAACACACAAAACAAAC ATGAAAAGGTAGTTAGTTGGGTTGTAACAGCTTACTGGGGTGGACTCATAAAACAGTGGCTTTCTGTTCATCTAAAGTTTCCTCAGATAC CACAGACCACTGTTAAGTGTGCTCATTGTCACTTTAAATTTCAACGATACCCTATTTTTGTCATTCTAAATATCAGATGTACTATTGGTA TAATTGCACACCAAAAATAAGCCAAACAGTGCATTACGCTAACTGGATCCCTGCTTTTATGTGAGCTAAGGAAAGATGGAGCCAACTCCA ACGAGGGCCTCTTTTTCTCTCTTGTCTAGCCTGTTTCTAAACCGAATGATCCAGGATTCAAGCTTCTATTGTCAAGTGAAACTTTCCTCA GATGGACTCCAGGTAGCCAGGTCACCTAAACCTAGTGGTCCTGTGCGATGCTCTTTCTGCCAGTCCCTGAATCTCTGCAGCTTCTCTTAC CTGTCTTACCTGTAGTAAAGCACAATTGCAGTGGCGTCGCATTCAGAAGAAGGGAAGGTCAGCAGAGGCTATGCATGTTGTGTGATGATG AGTGTTTACAGCCACCTTCTCCTAAAACGAAATTTATACCGGGGTGGATAGTATTCCATTAGGTAGACTTATCGACTTTGCTAAGTGCTT TTTAGACAGCTTAAAAAATTTTCAAGATTTTAAAAGATGTATAAGGTTAAGTTTGCAAATATAATGGAAATGCTGTATATCTTTTGAAGT GATGAAATCCACGTTGGAATTTTAAAGAAAATATGTTGTAATAATGCTGTTGTAAGTAATATTTTAATGTCTCTTTGCCTGTTTTCTATT TCAGCACATTCATTGTGGTGAATGTTCATAGCATTATAACTGCTTAGCCATTGAATGATAACATTTGTTAGTGGAAATTGGAAAATTTAT TTGTGAAATTCTGCAGAATTCATTTTTCTATTTCCAATATTTGCTGAGGTTAAATAAAAATTTTCAAGCCATTGATGTAATAAAATATGA >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000262241_chr14_103177272_+_5174nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAAT GGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAA GAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCT GCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACA AACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACA GAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTA CAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAG ACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGAT GTCAGATATGCATCTGCCTCCTGAGAAACTGGTGGCTTTGAACACTTGGTGTGGACTACTGTGTTATCCGGGATATCAGGTATTATGAGA CATCACCTAGCCATCTGCATCACATCTCTCTGGACAAGCAGCTATTACCAAAAAAGGCATATACTTCCAGTCCTGTGCTCCATCTGCCTT AATTCTTTGCTCGTTCCTCCATGTTGGCGCCACTTCCCAGAGAGCTCCACTGCATCTCACACTCTGCCCACGTGCTGGGGAAGTCTCACG GCCTGCACATCTCTTGTGACTCTGGGAACCGCCTCTCCCGCCGGAGCCCCCGAGCCCCACCAATGGCAGCTCTTCCCAGTCAGCAGCTTC AGAGCAGGCAGTCTCCTTGGAAGGCCCGACTCTGTTCCTGCATGGCCTGCAGTTTCTACTTTGTGCATAGAGTCATTTTCAGAGTCACCG CGACCCTGTTGGCCTTCTAGAAAGTTTCTTTTGTTCTTTTCTGAGACAACCACCTAAGTGATAATACGCTTTTTTGGAAACTAATATATA TTGCCAGACTGCATCATAACCTTTATCATGCCAAGCATCCTGATGCAACTCACATTTCCCTAAACATGGGGTACAGTTATGATTTATAAA TTGAGTTGGCTTAAATCTCCCTCTTCTCCCTTCCCAAGTGTTACAAAGATCATTTACTGCAACTGTCGTTGGACACTGTAGCTTAAAGGG AACGTGGACCTCAATGCTTTCTGCCTTCAACTTTTCAGCATTGTGACCCCAGGGTGGTTGCCACCCCATCTTTTCCTGACCCCCCCCACC CCCCCACCTCCAAGAGGTTCGGCCCACATCACTGTACCTGGTGCTTGTAAATTTGGAATTGGTGCCTTCTCCTTTTGGCAACCATGGTTA TCAATCCTTTTTCTGTTTTAGTGTCTTATTTCTTCTTTCAAGTTATTTGCTAGCCAAAGATGACATCACTGAGATTAGGAGACAGGGGAG AGCTTGCTGCAGATTCTGACAGTGCAGATTTTAAATGTCAGGATATTAGAATAGCTGGCGCTGGTTTATGAAAGCTGCGCGTTGTTCCGC GTTCTCTCGGTGTGCCTGGCCTTTTATGTGGCACTCTGTATGTCAGTTTGTGTCCTTCATGTGCTGATGTGATTACACAAACACCATGCA CTCTCTTTTCATATCAGAGTACAGGACAGAGAAGTGATCAATGTATTGGTCTAGTGAGACTGAGATGAAAAGAAATAACCTACAGAGTGG TCTGTAATGCCTTTTGGTTGGACTGGGAACAAGTAAAAATTTCTAATAAACATTTTGAGACTTCCAGAATCACTTTTGTTATCTTATCAG ACCATGGGCCTGCTGAGGGTTGAGCAGACAGCCTGCATTCTAACATACCCTGTTCCCACCCCACGGCCATTCAGACTGCACTCAATACGC TGAAGTCGCTTTTGTTGTTGTTGTTGTTGTTTGCATCATTTGGATTTTTTTCCTGCTTTCAATACCAAAAAAATGCAGATGCTTTAAGGC CTAAACAGAATTCTGAAGAATTTAAAATATGCAATTAAAGTTTGATATGTTTTGTCTCCCAAGCACCTTGTTTTTTGTTGTTGTTGTTGT TGTTGAAGTCAGCTGATTTTCTCTTTAGAAAGAGGGTCAGCTAGAAACCTAGGTTTTTTGGAATTGTAAATTTTTTTTTAGTATAGTCTG GAGAGAAAGGTCATTCAAAAGGAAAGTACAATGGGACTTGCTGCCCTTCATCATCTCGTTCCCGTGCCAGGTGTGTGTTGGTCACGTAAA AGCCTGGGAAGCATCAGAGGAGTCCCGGATTGCTGCTGCTACCTGGAGACAGGGTTAGCAAAATAACACTAGTGATGAGGGAGAGGCTTC TTTTCACCATAAGCCTGCTGTGTACACCGAGGGCGGCAGGAGAAGCATGGGAAGGAGTCAGCCTAAGTTTGCACATTGCATAAAGGGTAC ACTAAGGTATGAGCTGAAGCTTTAGGTTCTCCGTGCTTCCCTCAAGACCTCCTTCTTGCTAACAGAAGCAGTAGGCAATTGCTGCAGTGC GTTTCTCACCCTGCCAATAGGTCTGTCTGTATCTCTGTTAAGGAAAATAGCCTGGTCCCTCCTGGCAGTGCTTGGAAGCTTGATGCTAAT TTTTATATAGCGTGGCAAACTGACCAGCAGTGCCAGGCCTTGATCTGTATTCTGCACTATCCCTTTACTTGGTTCCTGGCACTGAATGGT CTCCAGCCCTGAAGAATCACGTGTGATCACAGCAGCTGACCTGGGCTTTCTCCCCGAGAGGAAGGGGCATGTCATTTTTATTTGACAGAG GGAAAATGGGAGCTGTCCTTGACTGCCTTTGTTGTGCTTTCCCGCGTAAGATAGCACTGTGTTTTAAACTGTTGCATTACACTGTCTTTG CAATGATGTAAATGTAAGAAATCACTTAGCTTTAAAAGCGCAGTGGTTTGATCTTATTTATATGAAGACTTTTTAACATATCAAGAATTA GGTGCATTGGCAGGTAGGGTTTGGGGTGTGATAACTGCTTCAGATGGAATGTTCACTTAAGCTTTGTCTTCTTAAAAATTATCAATGTGA ATGTCATAATTATATATATTTTTGTGGAAAATTTTCTCCTAAGTATAAGTTATTGTGCAAAATATAGTGTCATTGATGCAAATAATAGTT TAACTTTTAGTTTAGAACTCCTAAAAGATATAAATTGTATTGCATATGCATTAAAAGTTTGTTTTATTTAATTTTATGTAGATGTGTGAA GTGTTAGGTAAAATTTTTTTCACTTATCCATTTAAACACCTTGTTACTTGAATATTGTGTTGACTGGTCTGCAACAGTGATCCATTCTGT AATATAGCTCTTTTAACTGGGAAGGAACCACACCCCAGTTGTGCCGATTACATTAGTGTTGGCACACAGTCGGGTGCTAGTGTAACACAA ATGCCGCGTTGTCTGGGTGTACAGTGTTTGTGGAGACGCCACTTCCTCAAAATGGTTTTTGATTGTTTTTAACCTATAAGACGTTCTGAT GCTCACAAACCTCTATTCAACACACAAAACAAACATGAAAAGGTAGTTAGTTGGGTTGTAACAGCTTACTGGGGTGGACTCATAAAACAG TGGCTTTCTGTTCATCTAAAGTTTCCTCAGATACCACAGACCACTGTTAAGTGTGCTCATTGTCACTTTAAATTTCAACGATACCCTATT TTTGTCATTCTAAATATCAGATGTACTATTGGTATAATTGCACACCAAAAATAAGCCAAACAGTGCATTACGCTAACTGGATCCCTGCTT TTATGTGAGCTAAGGAAAGATGGAGCCAACTCCAACGAGGGCCTCTTTTTCTCTCTTGTCTAGCCTGTTTCTAAACCGAATGATCCAGGA TTCAAGCTTCTATTGTCAAGTGAAACTTTCCTCAGATGGACTCCAGGTAGCCAGGTCACCTAAACCTAGTGGTCCTGTGCGATGCTCTTT CTGCCAGTCCCTGAATCTCTGCAGCTTCTCTTACCTGTCTTACCTGTAGTAAAGCACAATTGCAGTGGCGTCGCATTCAGAAGAAGGGAA GGTCAGCAGAGGCTATGCATGTTGTGTGATGATGAGTGTTTACAGCCACCTTCTCCTAAAACGAAATTTATACCGGGGTGGATAGTATTC CATTAGGTAGACTTATCGACTTTGCTAAGTGCTTTTTAGACAGCTTAAAAAATTTTCAAGATTTTAAAAGATGTATAAGGTTAAGTTTGC AAATATAATGGAAATGCTGTATATCTTTTGAAGTGATGAAATCCACGTTGGAATTTTAAAGAAAATATGTTGTAATAATGCTGTTGTAAG TAATATTTTAATGTCTCTTTGCCTGTTTTCTATTTCAGCACATTCATTGTGGTGAATGTTCATAGCATTATAACTGCTTAGCCATTGAAT GATAACATTTGTTAGTGGAAATTGGAAAATTTATTTGTGAAATTCTGCAGAATTCATTTTTCTATTTCCAATATTTGCTGAGGTTAAATA >In-frame_XPC_ENST00000449060_chr3_14209757_-_RCOR1_ENST00000570597_chr14_103177272_+_5173nt ATGGCTCGGAAACGCGCGGCCGGCGGGGAGCCGCGGGGACGCGAACTGCGCAGCCAGAAATCCAAGGCCAAGAGCAAGGCCCGGCGTGAG GAGGAGGAGGAGGATGCCTTTGAAGATGAGAAACCCCCAAAGAAGAGCCTTCTCTCCAAAGTTTCACAAGGAAAGAGGAAAAGAGGCTGC AGTCATCCTGGGGGTTCAGCAGATGGTCCAGCAAAAAAGAAAGTGGCCAAGGTGACTGTTAAATCTGAAAACCTCAAGGTTATAAAGGAT GAAGCCCTCAGCGATGGGGATGACCTCAGGGACTTTCCAAGTGACCTCAAGAAGGCACACCATCTGAAGAGAGGGGCTACCATGAATGAA GACAGCAATGAAGAAGAGGAAGAAAGTGAAAATGATTGGGAAGAGGCGAAGACAAGAGAAAGAAGCGAGGATGAACTGGAAGAGGCAAAT GGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGCAAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAA GAAAAACATAGCACACAAGCTAAAAATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCT GCCAATGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAGAATATTAAACAGACA AACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAGAGGTCATTCAGAAATGTAATGCACGTTGGACTACA GAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAAATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTA CAAGTGAAAAACTTTTTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAGAAGAG ACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGAGGAAGACGAGGCTCCTGTTCTGGAT GTCAGATATGCATCTGCCTCCTGAGAAACTGGTGGCTTTGAACACTTGGTGTGGACTACTGTGTTATCCGGGATATCAGGTATTATGAGA CATCACCTAGCCATCTGCATCACATCTCTCTGGACAAGCAGCTATTACCAAAAAAGGCATATACTTCCAGTCCTGTGCTCCATCTGCCTT AATTCTTTGCTCGTTCCTCCATGTTGGCGCCACTTCCCAGAGAGCTCCACTGCATCTCACACTCTGCCCACGTGCTGGGGAAGTCTCACG GCCTGCACATCTCTTGTGACTCTGGGAACCGCCTCTCCCGCCGGAGCCCCCGAGCCCCACCAATGGCAGCTCTTCCCAGTCAGCAGCTTC AGAGCAGGCAGTCTCCTTGGAAGGCCCGACTCTGTTCCTGCATGGCCTGCAGTTTCTACTTTGTGCATAGAGTCATTTTCAGAGTCACCG CGACCCTGTTGGCCTTCTAGAAAGTTTCTTTTGTTCTTTTCTGAGACAACCACCTAAGTGATAATACGCTTTTTTGGAAACTAATATATA TTGCCAGACTGCATCATAACCTTTATCATGCCAAGCATCCTGATGCAACTCACATTTCCCTAAACATGGGGTACAGTTATGATTTATAAA TTGAGTTGGCTTAAATCTCCCTCTTCTCCCTTCCCAAGTGTTACAAAGATCATTTACTGCAACTGTCGTTGGACACTGTAGCTTAAAGGG AACGTGGACCTCAATGCTTTCTGCCTTCAACTTTTCAGCATTGTGACCCCAGGGTGGTTGCCACCCCATCTTTTCCTGACCCCCCCCACC CCCCCACCTCCAAGAGGTTCGGCCCACATCACTGTACCTGGTGCTTGTAAATTTGGAATTGGTGCCTTCTCCTTTTGGCAACCATGGTTA TCAATCCTTTTTCTGTTTTAGTGTCTTATTTCTTCTTTCAAGTTATTTGCTAGCCAAAGATGACATCACTGAGATTAGGAGACAGGGGAG AGCTTGCTGCAGATTCTGACAGTGCAGATTTTAAATGTCAGGATATTAGAATAGCTGGCGCTGGTTTATGAAAGCTGCGCGTTGTTCCGC GTTCTCTCGGTGTGCCTGGCCTTTTATGTGGCACTCTGTATGTCAGTTTGTGTCCTTCATGTGCTGATGTGATTACACAAACACCATGCA CTCTCTTTTCATATCAGAGTACAGGACAGAGAAGTGATCAATGTATTGGTCTAGTGAGACTGAGATGAAAAGAAATAACCTACAGAGTGG TCTGTAATGCCTTTTGGTTGGACTGGGAACAAGTAAAAATTTCTAATAAACATTTTGAGACTTCCAGAATCACTTTTGTTATCTTATCAG ACCATGGGCCTGCTGAGGGTTGAGCAGACAGCCTGCATTCTAACATACCCTGTTCCCACCCCACGGCCATTCAGACTGCACTCAATACGC TGAAGTCGCTTTTGTTGTTGTTGTTGTTGTTTGCATCATTTGGATTTTTTTCCTGCTTTCAATACCAAAAAAATGCAGATGCTTTAAGGC CTAAACAGAATTCTGAAGAATTTAAAATATGCAATTAAAGTTTGATATGTTTTGTCTCCCAAGCACCTTGTTTTTTGTTGTTGTTGTTGT TGTTGAAGTCAGCTGATTTTCTCTTTAGAAAGAGGGTCAGCTAGAAACCTAGGTTTTTTGGAATTGTAAATTTTTTTTTAGTATAGTCTG GAGAGAAAGGTCATTCAAAAGGAAAGTACAATGGGACTTGCTGCCCTTCATCATCTCGTTCCCGTGCCAGGTGTGTGTTGGTCACGTAAA AGCCTGGGAAGCATCAGAGGAGTCCCGGATTGCTGCTGCTACCTGGAGACAGGGTTAGCAAAATAACACTAGTGATGAGGGAGAGGCTTC TTTTCACCATAAGCCTGCTGTGTACACCGAGGGCGGCAGGAGAAGCATGGGAAGGAGTCAGCCTAAGTTTGCACATTGCATAAAGGGTAC ACTAAGGTATGAGCTGAAGCTTTAGGTTCTCCGTGCTTCCCTCAAGACCTCCTTCTTGCTAACAGAAGCAGTAGGCAATTGCTGCAGTGC GTTTCTCACCCTGCCAATAGGTCTGTCTGTATCTCTGTTAAGGAAAATAGCCTGGTCCCTCCTGGCAGTGCTTGGAAGCTTGATGCTAAT TTTTATATAGCGTGGCAAACTGACCAGCAGTGCCAGGCCTTGATCTGTATTCTGCACTATCCCTTTACTTGGTTCCTGGCACTGAATGGT CTCCAGCCCTGAAGAATCACGTGTGATCACAGCAGCTGACCTGGGCTTTCTCCCCGAGAGGAAGGGGCATGTCATTTTTATTTGACAGAG GGAAAATGGGAGCTGTCCTTGACTGCCTTTGTTGTGCTTTCCCGCGTAAGATAGCACTGTGTTTTAAACTGTTGCATTACACTGTCTTTG CAATGATGTAAATGTAAGAAATCACTTAGCTTTAAAAGCGCAGTGGTTTGATCTTATTTATATGAAGACTTTTTAACATATCAAGAATTA GGTGCATTGGCAGGTAGGGTTTGGGGTGTGATAACTGCTTCAGATGGAATGTTCACTTAAGCTTTGTCTTCTTAAAAATTATCAATGTGA ATGTCATAATTATATATATTTTTGTGGAAAATTTTCTCCTAAGTATAAGTTATTGTGCAAAATATAGTGTCATTGATGCAAATAATAGTT TAACTTTTAGTTTAGAACTCCTAAAAGATATAAATTGTATTGCATATGCATTAAAAGTTTGTTTTATTTAATTTTATGTAGATGTGTGAA GTGTTAGGTAAAATTTTTTTCACTTATCCATTTAAACACCTTGTTACTTGAATATTGTGTTGACTGGTCTGCAACAGTGATCCATTCTGT AATATAGCTCTTTTAACTGGGAAGGAACCACACCCCAGTTGTGCCGATTACATTAGTGTTGGCACACAGTCGGGTGCTAGTGTAACACAA ATGCCGCGTTGTCTGGGTGTACAGTGTTTGTGGAGACGCCACTTCCTCAAAATGGTTTTTGATTGTTTTTAACCTATAAGACGTTCTGAT GCTCACAAACCTCTATTCAACACACAAAACAAACATGAAAAGGTAGTTAGTTGGGTTGTAACAGCTTACTGGGGTGGACTCATAAAACAG TGGCTTTCTGTTCATCTAAAGTTTCCTCAGATACCACAGACCACTGTTAAGTGTGCTCATTGTCACTTTAAATTTCAACGATACCCTATT TTTGTCATTCTAAATATCAGATGTACTATTGGTATAATTGCACACCAAAAATAAGCCAAACAGTGCATTACGCTAACTGGATCCCTGCTT TTATGTGAGCTAAGGAAAGATGGAGCCAACTCCAACGAGGGCCTCTTTTTCTCTCTTGTCTAGCCTGTTTCTAAACCGAATGATCCAGGA TTCAAGCTTCTATTGTCAAGTGAAACTTTCCTCAGATGGACTCCAGGTAGCCAGGTCACCTAAACCTAGTGGTCCTGTGCGATGCTCTTT CTGCCAGTCCCTGAATCTCTGCAGCTTCTCTTACCTGTCTTACCTGTAGTAAAGCACAATTGCAGTGGCGTCGCATTCAGAAGAAGGGAA GGTCAGCAGAGGCTATGCATGTTGTGTGATGATGAGTGTTTACAGCCACCTTCTCCTAAAACGAAATTTATACCGGGGTGGATAGTATTC CATTAGGTAGACTTATCGACTTTGCTAAGTGCTTTTTAGACAGCTTAAAAAATTTTCAAGATTTTAAAAGATGTATAAGGTTAAGTTTGC AAATATAATGGAAATGCTGTATATCTTTTGAAGTGATGAAATCCACGTTGGAATTTTAAAGAAAATATGTTGTAATAATGCTGTTGTAAG TAATATTTTAATGTCTCTTTGCCTGTTTTCTATTTCAGCACATTCATTGTGGTGAATGTTCATAGCATTATAACTGCTTAGCCATTGAAT GATAACATTTGTTAGTGGAAATTGGAAAATTTATTTGTGAAATTCTGCAGAATTCATTTTTCTATTTCCAATATTTGCTGAGGTTAAATA |
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FusionGenePPI for XPC_RCOR1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| XPC | RAD23A, CETN2, RAD23B, ERCC3, SMARCB1, ATR, ATM, H2AFX, CHAF1A, BANF1, DDB1, DDB2, UBE4B, GTF2H1, XPA, HMGB1, RPA1, MECP2, WRAP53, CHRAC1, ZCCHC6, USP11, TOP2B, POU5F1, SMAD1, ZNF512B, RNF111, LSM3, TP53, MDM2, UBC, PSMD4, USP7, RPA4, SPIN2B, RPA2, RNF146, SIRT6, POLB, CSNK2A2, APLF, HIST1H2BA, TDG, HIST1H2BG, HIST1H3A, NPM1, EMC2, PHF8, CETN1, HIST1H2BO, HIST1H2BD, PARP2, CETN3, CHD1L, MACROD1, XRCC6, SSRP1, APOBEC3C, H2AFY2, SUPT16H, PARP1, NAA40, HIST2H2AB, WDR76, SDC2, HIST1H2AG, H2AFY, HIST2H4A, TSEN2, ALX3, ZNF428, MTF1 | RCOR1 | HDAC1, KDM1A, HMG20B, PHF21A, HDAC2, ZNF217, REST, MECP2, ZMYM2, CTBP1, KDM5B, CTBP2, HSPA4, SUMO2, ESCO2, SMARCE1, SMARCA4, SMARCC2, HIST1H3A, NR2E1, EMD, SERPINH1, SNAI1, MED12, MED28, TRIP4, OBFC1, BCL3, SUB1, GFI1B, GFI1, TAL1, HIST3H3, RCOR1, TCF3, NR2C1, TP53BP1, MTA3, NPM1, HDAC3, ECE2, FGF1, DOK4, ARRDC1, DDX46, MED23, B9D2, CEP135, NINL, SCLT1, HMG20A, FBXW7, NFATC2, DCAF12L2, ZSCAN5A, LLGL2, NR3C1, AR, PKN3, NCKAP5L, TFPT, CCHCR1, YEATS4, TUFT1, RABGAP1L, GOLGA5, CLOCK, PSMD9, VPS53, DZIP3, GRIPAP1, CCDC132, CCDC93, OIP5, PTRF, PHLDB3, HAUS6, RPRD1A, ARNTL, MAX, GIT2, RABGEF1, NUF2, THAP11, VPS51, TSSC1, RABEP1, TRIM25, UHRF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 296_384 | 256 | 483 | KDM1A |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 847_866 | 178 | 941 | CETN2 |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 847_866 | 141 | 904 | CETN2 |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 816_940 | 178 | 941 | ERCC2 and GTF2H1 |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 816_940 | 141 | 904 | ERCC2 and GTF2H1 |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000285021 | - | 4 | 16 | 496_734 | 178 | 941 | RAD23B |
| Hgene | XPC | chr3:14209757 | chr14:103177272 | ENST00000449060 | - | 4 | 16 | 496_734 | 141 | 904 | RAD23B |
| Tgene | RCOR1 | chr3:14209757 | chr14:103177272 | ENST00000570597 | + | 5 | 12 | 78_257 | 256 | 483 | HDAC1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for XPC_RCOR1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for XPC_RCOR1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | XPC | C2752147 | XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C | 2 | CTD_human;UNIPROT |
| Hgene | XPC | C0002514 | Amino Acid Metabolism, Inborn Errors | 1 | CTD_human |
| Hgene | XPC | C0004352 | Autistic Disorder | 1 | CTD_human |
| Hgene | XPC | C0008625 | Chromosome Aberrations | 1 | CTD_human |
| Hgene | XPC | C0024121 | Lung Neoplasms | 1 | CTD_human |
| Hgene | XPC | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
| Hgene | XPC | C1449861 | Micronuclei, Chromosome-Defective | 1 | CTD_human |
| Tgene | RCOR1 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
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