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Fusion gene ID: 4214 |
FusionGeneSummary for BLNK_ZNF536 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BLNK_ZNF536 | Fusion gene ID: 4214 | Hgene | Tgene | Gene symbol | BLNK | ZNF536 | Gene ID | 29760 | 9745 |
| Gene name | B cell linker | zinc finger protein 536 | |
| Synonyms | AGM4|BASH|BLNK-S|LY57|SLP-65|SLP65|bca | - | |
| Cytomap | 10q24.1 | 19q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | B-cell linker proteinB cell adaptor containing SH2 domainB-cell activationB-cell adapter containing a SH2 domain proteinB-cell adapter containing a Src homology 2 domain proteinSrc homology 2 domain-containing leukocyte protein of 65 kDaSrc homology | zinc finger protein 536 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8WV28 | O15090 | |
| Ensembl transtripts involved in fusion gene | ENST00000224337, ENST00000371176, ENST00000427367, ENST00000413476, ENST00000495266, | ENST00000355537, ENST00000590564, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 7 X 3 X 6=126 |
| # samples | 3 | 7 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BLNK [Title/Abstract] AND ZNF536 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | BLNK | GO:0035556 | intracellular signal transduction | 9341187 |
| Tgene | ZNF536 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 19398580 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A8-A08I-01A | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000224337 | ENST00000355537 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| 5CDS-intron | ENST00000224337 | ENST00000590564 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| In-frame | ENST00000371176 | ENST00000355537 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| 5CDS-intron | ENST00000371176 | ENST00000590564 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| In-frame | ENST00000427367 | ENST00000355537 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| 5CDS-intron | ENST00000427367 | ENST00000590564 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| In-frame | ENST00000413476 | ENST00000355537 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| 5CDS-intron | ENST00000413476 | ENST00000590564 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| In-frame | ENST00000495266 | ENST00000355537 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
| 5CDS-intron | ENST00000495266 | ENST00000590564 | BLNK | chr10 | 98002491 | - | ZNF536 | chr19 | 31025754 | + |
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FusionProtFeatures for BLNK_ZNF536 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BLNK | ZNF536 |
| Functions as a central linker protein, downstream of theB-cell receptor (BCR), bridging the SYK kinase to a multitude ofsignaling pathways and regulating biological outcomes of B-cellfunction and development. Plays a role in the activation ofERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation.Important for the activation of NF-kappa-B and NFAT. Plays animportant role in BCR-mediated PLCG1 and PLCG2 activation andCa(2+) mobilization and is required for trafficking of the BCR tolate endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3(PI3) kinase signaling. May be required for the RAC1-JNK pathway.Plays a critical role in orchestrating the pro-B cell to pre-Bcell transition. May play an important role in BCR-induced B-cellapoptosis. {ECO:0000269|PubMed:10583958,ECO:0000269|PubMed:15270728, ECO:0000269|PubMed:16912232,ECO:0000269|PubMed:9697839}. | May be involved in transcriptional regulation.Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 751_773 | 723 | 1301 | Zinc finger | C2H2-type 8 |
| Tgene | >ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 779_801 | 723 | 1301 | Zinc finger | C2H2-type 9 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000224337 | - | 3 | 17 | 98_260 | 54 | 457 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000371176 | - | 3 | 16 | 98_260 | 54 | 434 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000413476 | - | 3 | 16 | 98_260 | 54 | 405 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000224337 | - | 3 | 17 | 346_453 | 54 | 457 | Domain | SH2 |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000371176 | - | 3 | 16 | 346_453 | 54 | 434 | Domain | SH2 |
| Hgene | >BLNK | chr10:98002491 | chr19:31025754 | ENST00000413476 | - | 3 | 16 | 346_453 | 54 | 405 | Domain | SH2 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 130_152 | 723 | 1301 | Zinc finger | C2H2-type 1 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 158_180 | 723 | 1301 | Zinc finger | C2H2-type 2 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 274_297 | 723 | 1301 | Zinc finger | C2H2-type 3 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 300_323 | 723 | 1301 | Zinc finger | C2H2-type 4 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 345_367 | 723 | 1301 | Zinc finger | C2H2-type 5 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 373_395 | 723 | 1301 | Zinc finger | C2H2-type 6 |
| Tgene | ZNF536 | chr10:98002491 | chr19:31025754 | ENST00000355537 | + | 1 | 5 | 631_653 | 723 | 1301 | Zinc finger | C2H2-type 7 |
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FusionGeneSequence for BLNK_ZNF536 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BLNK_ENST00000224337_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_632aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGID FRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDK ALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAK RKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYP GMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSL QPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCG >In-frame_BLNK_ENST00000371176_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_632aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGID FRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDK ALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAK RKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYP GMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSL QPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCG >In-frame_BLNK_ENST00000427367_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_632aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGID FRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDK ALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAK RKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYP GMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSL QPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCG >In-frame_BLNK_ENST00000413476_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_632aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGID FRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDK ALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAK RKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYP GMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSL QPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCG >In-frame_BLNK_ENST00000495266_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_632aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGID FRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDK ALADPPSMKVHGVDGGEEKPSGKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLGKAK RKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYP GMVGSGASSSCPNKEPDGKAHSEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKDSSSDGGDSL QPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDKPMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BLNK_ENST00000224337_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_1896nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT >In-frame_BLNK_ENST00000371176_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_1896nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT >In-frame_BLNK_ENST00000427367_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_1896nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT >In-frame_BLNK_ENST00000413476_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_1896nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT >In-frame_BLNK_ENST00000495266_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_1896nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BLNK_ENST00000224337_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_2933nt GCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGAGGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACT GCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCA GAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGC ACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCTGGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCG CGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACTTTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGAT ACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACGCAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCA TCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAAGACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTT CATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGACTTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGG GGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAGGTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTC CAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGCAACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCAT GGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAAGCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGT GGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAGAAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCC AGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCATGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTC CATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAACGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAA AGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCAAACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCT AGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGAGAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCC TGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCAGGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAA CAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATCCCCGAAACCACGAGTAAGAACACTACTGATGACCTCTC TGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGATGAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAA GCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTGCAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGT CTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTCCAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGA GCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGGGCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACT TGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGTAAGTGACACTCCCTGTCCTAGTCGGTCTATCTGGACTT GCCCTTGTCTGTTCGTGGTCCTCGGTGGTTATCTGCAGCTTGTTAATCGTGTAAAGTCAAGAGAAGAATGTATACACATATGTGTGTTGA ATAATTACTATTGGCATAGGTATGTGTATACACACGGTGCACCAATCTACAGTATATATAGCAGAGAATCAGAGGCTAAAAATATTACCC CATATGTTCCAGTATTAGTCATGGATTGCAAAGGCTTAGTAACTTGAGCAGGAGAGAAAACTCCCTCAAAGTCATAAATCCTGAGTGACA ACTGCTGCTGGATGACAGATCCCTTCACCTGTGGACAACCTGGCTGGGGGTGGGGGGCTGTTCCACCAGCTCACCTGAGCATGTAGAGGT GGGTCCTGCAGTGGTCTCGTGGGTATTACTGCTTGTGTCTGATTGTCCTGTATTTTGTAACACTTTAGAAGAATACAGAAAAGTGCAGTA ATTCTCTTTCTCCATAGTATTTAAGCAGAAATATTGCTAGTTTAATATTGTGTCAGGTCGTCCTATTAACCAGGAGCAGATGACAGTAAA ATTTCAGTGAATAGCACCTTGACATCTACAACTTAAAAATGGTGATTGAAGCAAAATATGTAAACTTGTACGGGGTGATCGTGTGCTTTG GAACAGAGTATTGTTGAAGTAATTAGAAGATATATTAAGGTGTTCCTGGTAATGAAGGCATGTAAGTTATAATAATTGTAGCTTTCTGAA TAAGTGTCAAACTATATCTTTAAGTGTGCTGTATGCTGAGTTACAAGTTAGGTCATTTATGAATGGAATGTAAAATAATACTAAAAATGC >In-frame_BLNK_ENST00000371176_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_2933nt GCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGAGGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACT GCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCA GAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGC ACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCTGGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCG CGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACTTTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGAT ACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACGCAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCA TCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAAGACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTT CATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGACTTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGG GGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAGGTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTC CAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGCAACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCAT GGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAAGCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGT GGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAGAAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCC AGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCATGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTC CATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAACGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAA AGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCAAACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCT AGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGAGAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCC TGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCAGGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAA CAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATCCCCGAAACCACGAGTAAGAACACTACTGATGACCTCTC TGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGATGAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAA GCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTGCAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGT CTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTCCAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGA GCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGGGCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACT TGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGTAAGTGACACTCCCTGTCCTAGTCGGTCTATCTGGACTT GCCCTTGTCTGTTCGTGGTCCTCGGTGGTTATCTGCAGCTTGTTAATCGTGTAAAGTCAAGAGAAGAATGTATACACATATGTGTGTTGA ATAATTACTATTGGCATAGGTATGTGTATACACACGGTGCACCAATCTACAGTATATATAGCAGAGAATCAGAGGCTAAAAATATTACCC CATATGTTCCAGTATTAGTCATGGATTGCAAAGGCTTAGTAACTTGAGCAGGAGAGAAAACTCCCTCAAAGTCATAAATCCTGAGTGACA ACTGCTGCTGGATGACAGATCCCTTCACCTGTGGACAACCTGGCTGGGGGTGGGGGGCTGTTCCACCAGCTCACCTGAGCATGTAGAGGT GGGTCCTGCAGTGGTCTCGTGGGTATTACTGCTTGTGTCTGATTGTCCTGTATTTTGTAACACTTTAGAAGAATACAGAAAAGTGCAGTA ATTCTCTTTCTCCATAGTATTTAAGCAGAAATATTGCTAGTTTAATATTGTGTCAGGTCGTCCTATTAACCAGGAGCAGATGACAGTAAA ATTTCAGTGAATAGCACCTTGACATCTACAACTTAAAAATGGTGATTGAAGCAAAATATGTAAACTTGTACGGGGTGATCGTGTGCTTTG GAACAGAGTATTGTTGAAGTAATTAGAAGATATATTAAGGTGTTCCTGGTAATGAAGGCATGTAAGTTATAATAATTGTAGCTTTCTGAA TAAGTGTCAAACTATATCTTTAAGTGTGCTGTATGCTGAGTTACAAGTTAGGTCATTTATGAATGGAATGTAAAATAATACTAAAAATGC >In-frame_BLNK_ENST00000427367_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_2969nt AAGTTTTACTTCTCCCTAGAGCAGGGGTGTTTGCCAGCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGA GGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAAT GGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGG AATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCTGG GAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACTTT CCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACGCA GTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAAGA CCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGACTT CAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAGGT CCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGCAA CGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAAGC CCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAGAA ATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCATG GCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAACG CAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCAAA CAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGAGA GCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCAGG CATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATCCC CGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGATGA AGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTGCA GCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTCCA AGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGGGC CTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGTAA GTGACACTCCCTGTCCTAGTCGGTCTATCTGGACTTGCCCTTGTCTGTTCGTGGTCCTCGGTGGTTATCTGCAGCTTGTTAATCGTGTAA AGTCAAGAGAAGAATGTATACACATATGTGTGTTGAATAATTACTATTGGCATAGGTATGTGTATACACACGGTGCACCAATCTACAGTA TATATAGCAGAGAATCAGAGGCTAAAAATATTACCCCATATGTTCCAGTATTAGTCATGGATTGCAAAGGCTTAGTAACTTGAGCAGGAG AGAAAACTCCCTCAAAGTCATAAATCCTGAGTGACAACTGCTGCTGGATGACAGATCCCTTCACCTGTGGACAACCTGGCTGGGGGTGGG GGGCTGTTCCACCAGCTCACCTGAGCATGTAGAGGTGGGTCCTGCAGTGGTCTCGTGGGTATTACTGCTTGTGTCTGATTGTCCTGTATT TTGTAACACTTTAGAAGAATACAGAAAAGTGCAGTAATTCTCTTTCTCCATAGTATTTAAGCAGAAATATTGCTAGTTTAATATTGTGTC AGGTCGTCCTATTAACCAGGAGCAGATGACAGTAAAATTTCAGTGAATAGCACCTTGACATCTACAACTTAAAAATGGTGATTGAAGCAA AATATGTAAACTTGTACGGGGTGATCGTGTGCTTTGGAACAGAGTATTGTTGAAGTAATTAGAAGATATATTAAGGTGTTCCTGGTAATG AAGGCATGTAAGTTATAATAATTGTAGCTTTCTGAATAAGTGTCAAACTATATCTTTAAGTGTGCTGTATGCTGAGTTACAAGTTAGGTC >In-frame_BLNK_ENST00000413476_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_2969nt AAGTTTTACTTCTCCCTAGAGCAGGGGTGTTTGCCAGCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGA GGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAAT GGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGG AATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCTGG GAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACTTT CCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACGCA GTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAAGA CCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGACTT CAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAGGT CCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGCAA CGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAAGC CCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAGAA ATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCATG GCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAACG CAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCAAA CAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGAGA GCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCAGG CATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATCCC CGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGATGA AGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTGCA GCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTCCA AGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGGGC CTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGTAA GTGACACTCCCTGTCCTAGTCGGTCTATCTGGACTTGCCCTTGTCTGTTCGTGGTCCTCGGTGGTTATCTGCAGCTTGTTAATCGTGTAA AGTCAAGAGAAGAATGTATACACATATGTGTGTTGAATAATTACTATTGGCATAGGTATGTGTATACACACGGTGCACCAATCTACAGTA TATATAGCAGAGAATCAGAGGCTAAAAATATTACCCCATATGTTCCAGTATTAGTCATGGATTGCAAAGGCTTAGTAACTTGAGCAGGAG AGAAAACTCCCTCAAAGTCATAAATCCTGAGTGACAACTGCTGCTGGATGACAGATCCCTTCACCTGTGGACAACCTGGCTGGGGGTGGG GGGCTGTTCCACCAGCTCACCTGAGCATGTAGAGGTGGGTCCTGCAGTGGTCTCGTGGGTATTACTGCTTGTGTCTGATTGTCCTGTATT TTGTAACACTTTAGAAGAATACAGAAAAGTGCAGTAATTCTCTTTCTCCATAGTATTTAAGCAGAAATATTGCTAGTTTAATATTGTGTC AGGTCGTCCTATTAACCAGGAGCAGATGACAGTAAAATTTCAGTGAATAGCACCTTGACATCTACAACTTAAAAATGGTGATTGAAGCAA AATATGTAAACTTGTACGGGGTGATCGTGTGCTTTGGAACAGAGTATTGTTGAAGTAATTAGAAGATATATTAAGGTGTTCCTGGTAATG AAGGCATGTAAGTTATAATAATTGTAGCTTTCTGAATAAGTGTCAAACTATATCTTTAAGTGTGCTGTATGCTGAGTTACAAGTTAGGTC >In-frame_BLNK_ENST00000495266_chr10_98002491_-_ZNF536_ENST00000355537_chr19_31025754_+_2791nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGACATTGGCGAGGAGGCT GGGAGATCTGCCGGCGTCCAGCAACCAGCGCTGCTTCGCGACAGAAGCCTGGGCTCGGCCATGAAGGACTGCCCGTACTGTGGGAAAACT TTCCGGACATCCCATCACCTTAAGGTGCACCTGAGGATACACACAGGTGAGAAACCCTACAAGTGTCCGCACTGTGACTATGCCGGCACG CAGTCAGCATCCTTAAAATACCACTTAGAGCGACACCATCGGGAGCGGCAGAACGGGGCTGGGCCGCTGTCTGGGCAACCCCCAAATCAA GACCACAAGGATGAGATGTCAAGCAAAGCTTCTCTGTTCATCAGGCCAGACATCCTGAGGGGGGCCTTCAAGGGTCTCCCTGGAATCGAC TTCAGAGGAGGCCCTGCATCTCAGCAGTGGACATCAGGGGTTCTCTCCTCTGGAGATCACTCGGGGCAGGCCACGGGCATGTCTTCGGAG GTCCCCTCAGATGCTCTGAAAGGCACTGACCTTCCTTCCAAAAGCACCCACTTCTCTGAGATCGGAAGAGCTTATCAAAGCATTGTGAGC AACGGTGTGAATTTCCAAGGGTCCTTGCAAGCTTTCATGGACAGTTTTGTCCTCAGTTCCTTGAAGAAGGAGAAGGACATGAAGGACAAA GCCCTGGCTGACCCCCCTTCCATGAAAGTCCACGGAGTGGATGGTGGTGAGGAGAAACCCAGTGGCAAGTCCTCCCAGAGGAAGTCCGAG AAATCTCAGTATGAACCCCTGGACTTGTCTGTGCGGCCAGATGCCGCCTCCCTCCCGGGCTCCTCGGTAACTGTGCAGGACAGCATTGCA TGGCACGGCTGCTTGTTTTGTGCTTTCACAACGTCCTCCATGGAGCTCATGGCCCTTCATCTCCAGGCCAACCACCTGGGCAAAGCGAAA CGCAAAGATAACACCATCGGGGTCACAGTCAACTGCAAAGACCAAGCCCGGGAGGCGAGTAAGATGGCCCTGCTGCCCTCGTTACAATCA AACAAAGACCTGGGCCTCTCCAATATGATCAGCTCTCTAGACTCTGCTTCTGAGAAGATGGCCCAAGGTCAGCTCAAGGAGACTCTGGGA GAGCAGAAGAGCGGTGCATGGACCGGCCACGTGGACCCTGCATTTTGTAACTTCCCATCAGACTTCTACAAGCAGTTTGGTGTTTACCCA GGCATGGTTGGCTCAGGGGCCTCCAGTTCCTGCCCCAACAAGGAGCCTGATGGAAAGGCCCACTCTGAAGAGGATGTCCCCATCCTGATC CCCGAAACCACGAGTAAGAACACTACTGATGACCTCTCTGACATTGCCTCCTCAGAGGACATGGACTCCTCCAAGGGGGAGAACAACGAT GAAGAGGATGTTGAAACCGAACCGGAAATGATGACCAAGCCACTGTCTGCCCTCAGCAAAGACAGCAGCAGCGATGGCGGGGACAGCCTG CAGCCCACAGGCACCTCCCAGCCCGTCCAGGGACTGGTCTCACCTTTATCCCAAGCACCGGAGAAGCAGTGGCACAGCCAGGGTCTTCTC CAAGCCCAGGACCCCTTGGCGGGCCTGCCAAAGCCGGAGCGGGGGCCCCAGAGCCTGGACAAGCCGATGAACATGCTGTCGGTCCTCAGG GCCTACAGTTCTGATGGCTTAGCAGCCTTTAACGGACTTGCAAGTAGCACAGCAAATTCTGGATGTATCAAGAGGCCAGACTTGTGTGGT AAGTGACACTCCCTGTCCTAGTCGGTCTATCTGGACTTGCCCTTGTCTGTTCGTGGTCCTCGGTGGTTATCTGCAGCTTGTTAATCGTGT AAAGTCAAGAGAAGAATGTATACACATATGTGTGTTGAATAATTACTATTGGCATAGGTATGTGTATACACACGGTGCACCAATCTACAG TATATATAGCAGAGAATCAGAGGCTAAAAATATTACCCCATATGTTCCAGTATTAGTCATGGATTGCAAAGGCTTAGTAACTTGAGCAGG AGAGAAAACTCCCTCAAAGTCATAAATCCTGAGTGACAACTGCTGCTGGATGACAGATCCCTTCACCTGTGGACAACCTGGCTGGGGGTG GGGGGCTGTTCCACCAGCTCACCTGAGCATGTAGAGGTGGGTCCTGCAGTGGTCTCGTGGGTATTACTGCTTGTGTCTGATTGTCCTGTA TTTTGTAACACTTTAGAAGAATACAGAAAAGTGCAGTAATTCTCTTTCTCCATAGTATTTAAGCAGAAATATTGCTAGTTTAATATTGTG TCAGGTCGTCCTATTAACCAGGAGCAGATGACAGTAAAATTTCAGTGAATAGCACCTTGACATCTACAACTTAAAAATGGTGATTGAAGC AAAATATGTAAACTTGTACGGGGTGATCGTGTGCTTTGGAACAGAGTATTGTTGAAGTAATTAGAAGATATATTAAGGTGTTCCTGGTAA TGAAGGCATGTAAGTTATAATAATTGTAGCTTTCTGAATAAGTGTCAAACTATATCTTTAAGTGTGCTGTATGCTGAGTTACAAGTTAGG TCATTTATGAATGGAATGTAAAATAATACTAAAAATGCTTCAATAACTTATCTTGGTATTGCTAATAAAAAAAAAAAGCTGTGAAACATT |
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FusionGenePPI for BLNK_ZNF536 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BLNK | NCK1, VAV1, GRB2, MAP4K1, SH3KBP1, CD79A, CRKL, BTK, CD72, PTPN6, CD2AP, CAPZA1, CAPZA2, CAPZB, HSPA4, HSPH1, MYBPC3, CLEC17A, DOK3, NCK2, TLN1, LYN, SYK, PLCG2, VAV3, MAP2K4, PPP2R2C, AIFM1, WDR81, CBL, PLCG1, GRAP2, ERBB2 | ZNF536 | MMS19, SOX2, FAM96B, TEAD2, FOXC2, FOXJ2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BLNK_ZNF536 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BLNK_ZNF536 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ZNF536 | C0007134 | Renal Cell Carcinoma | 1 | CTD_human |
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