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Fusion gene ID: 4212 |
FusionGeneSummary for BLNK_PIK3AP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BLNK_PIK3AP1 | Fusion gene ID: 4212 | Hgene | Tgene | Gene symbol | BLNK | PIK3AP1 | Gene ID | 29760 | 118788 |
| Gene name | B cell linker | phosphoinositide-3-kinase adaptor protein 1 | |
| Synonyms | AGM4|BASH|BLNK-S|LY57|SLP-65|SLP65|bca | BCAP | |
| Cytomap | 10q24.1 | 10q24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | B-cell linker proteinB cell adaptor containing SH2 domainB-cell activationB-cell adapter containing a SH2 domain proteinB-cell adapter containing a Src homology 2 domain proteinSrc homology 2 domain-containing leukocyte protein of 65 kDaSrc homology | phosphoinositide 3-kinase adapter protein 1B cell adaptor proteinB-cell adapter for phosphoinositide 3-kinaseB-cell phosphoinositide 3-kinase adapter protein 1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8WV28 | Q6ZUJ8 | |
| Ensembl transtripts involved in fusion gene | ENST00000224337, ENST00000371176, ENST00000427367, ENST00000413476, ENST00000495266, | ENST00000339364, ENST00000468783, ENST00000371110, ENST00000371109, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 2 X 2 X 1=4 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: BLNK [Title/Abstract] AND PIK3AP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | BLNK | GO:0035556 | intracellular signal transduction | 9341187 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-S3-A6ZF-01A | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000224337 | ENST00000339364 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000224337 | ENST00000468783 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000224337 | ENST00000371110 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000224337 | ENST00000371109 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| In-frame | ENST00000371176 | ENST00000339364 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000371176 | ENST00000468783 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000371176 | ENST00000371110 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000371176 | ENST00000371109 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| In-frame | ENST00000427367 | ENST00000339364 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000427367 | ENST00000468783 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000427367 | ENST00000371110 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000427367 | ENST00000371109 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| In-frame | ENST00000413476 | ENST00000339364 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000413476 | ENST00000468783 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000413476 | ENST00000371110 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| 5CDS-5UTR | ENST00000413476 | ENST00000371109 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| intron-3CDS | ENST00000495266 | ENST00000339364 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| intron-5UTR | ENST00000495266 | ENST00000468783 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| intron-5UTR | ENST00000495266 | ENST00000371110 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
| intron-5UTR | ENST00000495266 | ENST00000371109 | BLNK | chr10 | 97976409 | - | PIK3AP1 | chr10 | 98388250 | - |
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FusionProtFeatures for BLNK_PIK3AP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BLNK | PIK3AP1 |
| Functions as a central linker protein, downstream of theB-cell receptor (BCR), bridging the SYK kinase to a multitude ofsignaling pathways and regulating biological outcomes of B-cellfunction and development. Plays a role in the activation ofERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation.Important for the activation of NF-kappa-B and NFAT. Plays animportant role in BCR-mediated PLCG1 and PLCG2 activation andCa(2+) mobilization and is required for trafficking of the BCR tolate endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3(PI3) kinase signaling. May be required for the RAC1-JNK pathway.Plays a critical role in orchestrating the pro-B cell to pre-Bcell transition. May play an important role in BCR-induced B-cellapoptosis. {ECO:0000269|PubMed:10583958,ECO:0000269|PubMed:15270728, ECO:0000269|PubMed:16912232,ECO:0000269|PubMed:9697839}. | Signaling adapter that contributes to B-cell developmentby linking B-cell receptor (BCR) signaling to the phosphoinositide3-kinase (PI3K)-Akt signaling pathway. Has a complementary role tothe BCR coreceptor CD19, coupling BCR and PI3K activation byproviding a docking site for the PI3K subunit PIK3R1.Alternatively, links Toll-like receptor (TLR) signaling to PI3Kactivation, a process preventing excessive inflammatory cytokineproduction. Also involved in the activation of PI3K in naturalkiller cells. May be involved in the survival of mature B-cellsvia activation of REL. {ECO:0000269|PubMed:15893754}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000339364 | - | 7 | 17 | 645_667 | 458 | 806 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371109 | - | 0 | 10 | 645_667 | 57 | 405 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371110 | - | 6 | 16 | 645_667 | 280 | 628 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000339364 | - | 7 | 17 | 760_802 | 458 | 806 | Compositional bias | Note=Pro-rich |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371109 | - | 0 | 10 | 760_802 | 57 | 405 | Compositional bias | Note=Pro-rich |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371110 | - | 6 | 16 | 760_802 | 280 | 628 | Compositional bias | Note=Pro-rich |
| Tgene | >PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371109 | - | 0 | 10 | 181_317 | 57 | 405 | Domain | DBB |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000224337 | - | 7 | 17 | 98_260 | 202 | 457 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000371176 | - | 7 | 16 | 98_260 | 202 | 434 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000413476 | - | 7 | 16 | 98_260 | 202 | 405 | Compositional bias | Note=Pro-rich |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000224337 | - | 7 | 17 | 346_453 | 202 | 457 | Domain | SH2 |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000371176 | - | 7 | 16 | 346_453 | 202 | 434 | Domain | SH2 |
| Hgene | >BLNK | chr10:97976409 | chr10:98388250 | ENST00000413476 | - | 7 | 16 | 346_453 | 202 | 405 | Domain | SH2 |
| Tgene | PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000339364 | - | 7 | 17 | 181_317 | 458 | 806 | Domain | DBB |
| Tgene | PIK3AP1 | chr10:97976409 | chr10:98388250 | ENST00000371110 | - | 6 | 16 | 181_317 | 280 | 628 | Domain | DBB |
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FusionGeneSequence for BLNK_PIK3AP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BLNK_ENST00000224337_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_550aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEE NADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV PVEDNDENYIHPTESSSPPPEKDVEMLQASTSNPIPGDGFSRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDL ASRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVK LGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPR TELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHP >In-frame_BLNK_ENST00000371176_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_550aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEE NADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV PVEDNDENYIHPTESSSPPPEKDVEMLQASTSNPIPGDGFSRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDL ASRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVK LGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPR TELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHP >In-frame_BLNK_ENST00000427367_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_550aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEE NADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV PVEDNDENYIHPTESSSPPPEKDVEMLQASTSNPIPGDGFSRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDL ASRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVK LGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPR TELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHP >In-frame_BLNK_ENST00000413476_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_550aa MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEE NADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV PVEDNDENYIHPTESSSPPPEKDVEMLQASTSNPIPGDGFSRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVDDDEAFSVDL ASRPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGPPVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVK LGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQREKQKSGKQTDLEITVPIRHSQHLPAKVEFGVYESGPRKSVIPPR TELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEVTRSRSPGPPQVDGTPTMSLERPPRVPPRAASQRPPTRETFHP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BLNK_ENST00000224337_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_1650nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAA GAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAG AACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATA GACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACC TCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTC CCCGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGT ACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATG ACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTG GCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAA GTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGG GACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAG CTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAG CAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACG GTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGG ACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTC AGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGAT GGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCT >In-frame_BLNK_ENST00000371176_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_1650nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAA GAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAG AACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATA GACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACC TCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTC CCCGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGT ACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATG ACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTG GCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAA GTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGG GACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAG CTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAG CAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACG GTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGG ACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTC AGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGAT GGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCT >In-frame_BLNK_ENST00000427367_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_1650nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAA GAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAG AACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATA GACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACC TCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTC CCCGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGT ACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATG ACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTG GCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAA GTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGG GACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAG CTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAG CAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACG GTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGG ACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTC AGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGAT GGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCT >In-frame_BLNK_ENST00000413476_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_1650nt ATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGT GGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAA GAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAG AACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATA GACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACC TCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTC CCCGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGT ACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATG ACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTG GCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAA GTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGG GACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAG CTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAG CAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACG GTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGG ACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTC AGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGAT GGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BLNK_ENST00000224337_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_4057nt GCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGAGGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACT GCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCA GAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGC ACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAAGAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGA AAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAGAACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCA GGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATAGACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAG CAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACCTCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCA AGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTCCCCGTGGAAGATAATGATGAAAACTATATTCATCCCAC AGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGTACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGC CACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATGACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGA AGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTGGCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGAC CACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAAGTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTT CTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGGGACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGG AATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAGCTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTT CAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAGCAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCG AAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACGGTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGT GGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGGACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCAC CTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTCAGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAA TGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGATGGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGT GCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCTCCTCCACCTGTTCCACCCAGAGGACGCTGATTCCACCT CCTAAAACCTGCCTACTTCAGGACTTTAAGACTCACAGTCTTCAGCCTGTTAATGATGTCTTCATGTTGAGTTTTATAGCATGACTGTTG ACCTTAAGATCCATTCTCATTGCTGATAATGCTGCAGCCCTGCTGGTTTGGGCTTGCCTCGAAGATTTTATTAAGGCACGAAGAAGTGAA AAACTAAGGGCTTCATTCACCATCACCAAGTATATCGAACCATATACTTGTTTGCCAAAAGGATGAAGACTTAATCGAAATACTTACCTC TAATTTGCCATATCAGAAGCCTAAAAAGAATGATCATAAATGTACTTCACCAGTGATTTTACTGAAATGCACTTATATTAGTCTTTATGT ATTTGCTAGTTCAGCCTGATTTCTAGAAGAGGTTATAGTGTGAGACTTGTAGTATTCAAGTAAGATAAGTGACCTAATTTTAAAATAATT CTTCTACTTTTCTGTATATTCAGCAGGGTATTTAAGTGCTAGGGCTGGTCACACACAACCAACTGAAAAAGACTAGAGGGATTAGTACAA ACTCCTCTTATACAGAAGGCAAATCTGAGGTTCCACAGAAGTCTGGAACCAAGACTATTCAGTTGGTTAAATAAAGAGGTTAGTCTAGAC TGGGCCTGCTCATTCTAGGTCACCACATTTTCCATCTCCAAATAGCCAGGCCCTCTCTCCCTCAAGAAATGCCCAGATGTAGAAATTCAT CAGTGCCTATTGGTCTTCCAGAATTTTCCATCTTCCGTATCTCCCAGGCATGAGACTACCAAGTTTGTTTGTTTTCTTTCCAATTTGGGA ATTTATACTTCAGTATGGTTTCAACGCAGTTATGTTTCCAGAGAACATCTAGAAGTGGCTGGAAACCAGAAGCTGGGGATTCCAGGGACC CCACTTAGTGCTCTATTTCCTTTATAGGTTTTATTTCTGGTCATAGAGAGAGAAGGACCTTTGACTTTTTCTTCGTTGAGGCTTCTGAGG AGGAAAAACAAACCTAAAATAGAAATACAGTCAGCCTTTCAAATCCATGGGTTCTGTGTCCGTGGATTCAACCAACCTTGGATCAAAAAT ATTTGAAAAAAAATCTACAAAGTTTCAAAAAGCAAAACTTGAATTTGCTGCATGCCAAGAAGTATGTTGAATTCATGTAAATGAAGTGAT GTGTAGGCATTGTATTAGATATTATAAGAAATCTAGAAATGATTTAAAGCATACAGGAGGATGTGCATAGGTTATATGCAAATACTATGC TATTTTATATATGGGACTTGAGCATTTGTGGATTTTGATACTGGGGGATCCTGGAACCAATCCCCCATGGATACCAAAGTACGACTGTAG TTATCTATTTTTTACATACTTATTATTACCACCATGCTCAGTAAGTCCATTTTTGCATGGAATATGGAGCCTTAAAACATGTCATGAATT TGGAGTCCCTGGCACATAAATCTACCTTCAAATCAGAGGTCCTTAATGATGCCTAAACATACAGTAAAATTAGAATCAGAAATACTTCTT TAAAAAATATTCAAAATGTGTTTGTTTCCCATGGGATTATTCTCTATCCCACACGAATGTAAAAAAATCCACATTAATGATCCATTTAAG TATAGTTTTATTGGGTCCTTTTCTAATGATTAAAGGTTCTTTCTCAATTTCATTCCTCAGTCCTGCAAGTAAGGACTCATACTGAAGAGT ACTGAAACAAGGACTTCTTGTCAGAAACAGCTTCTGGAATCTTGGGTTTTGTTTTTGTTTTTTGACAAAATACACTATTGGCCATGTCCA TCACGAGAGTGTTTGTAGTAATTAATTACCTTGTACAGGACCTGGCACTTAGTAGCATTCTTCAAATGTTCCCTCAGTGATCCTTTTACT CTCCTTGTCACTTATTTGGGAGAAATAGGGGCACGTGAGATAAGAAGAAGAATAATTTTGATGTTGGTATGCTTGCCCTGTTACTTATAG ACAGTCTTTGTCATAGGCAAACTTGAATTTGATTTAAAATAGGGCTGGGAAAAATATTCAATAACTGTAAGCCCCCTTTTGGATGCCAAA CTTAGAATTTTGTACATTCTCTGATGAACAAGCATTTAGATCGTAACATGGTAAAGCCTATTACCAGCCAATGTTGTTAGCATCTTTGTA TGCACATCACTGTTTGTGCAATATATGAATATTTTGTTGCATTGTATTCTTATATAAAAATAAGTAGAAAACATAAAATTGAAATTGCTG >In-frame_BLNK_ENST00000371176_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_4057nt GCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGAGGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACT GCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCA GAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGC ACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAAGAGGAGCAGTGGTCCGATGACTTTGACAGCGACTATGA AAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAGAACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCA GGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATAGACAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAG CAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACCTCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCA AGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTCCCCGTGGAAGATAATGATGAAAACTATATTCATCCCAC AGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGTACATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGC CACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATGACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGA AGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTGGCCAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGAC CACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAAGTTTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTT CTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGGGACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGG AATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAGCTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTT CAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAGCAGGAAAATCTTAAACGGCTAAGAGACAGCATCACCCG AAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACGGTCCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGT GGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGGACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCAC CTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTCAGTGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAA TGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGATGGGACACCCACCATGTCCCTCGAGAGACCCCCCAGGGT GCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCTCCTCCACCTGTTCCACCCAGAGGACGCTGATTCCACCT CCTAAAACCTGCCTACTTCAGGACTTTAAGACTCACAGTCTTCAGCCTGTTAATGATGTCTTCATGTTGAGTTTTATAGCATGACTGTTG ACCTTAAGATCCATTCTCATTGCTGATAATGCTGCAGCCCTGCTGGTTTGGGCTTGCCTCGAAGATTTTATTAAGGCACGAAGAAGTGAA AAACTAAGGGCTTCATTCACCATCACCAAGTATATCGAACCATATACTTGTTTGCCAAAAGGATGAAGACTTAATCGAAATACTTACCTC TAATTTGCCATATCAGAAGCCTAAAAAGAATGATCATAAATGTACTTCACCAGTGATTTTACTGAAATGCACTTATATTAGTCTTTATGT ATTTGCTAGTTCAGCCTGATTTCTAGAAGAGGTTATAGTGTGAGACTTGTAGTATTCAAGTAAGATAAGTGACCTAATTTTAAAATAATT CTTCTACTTTTCTGTATATTCAGCAGGGTATTTAAGTGCTAGGGCTGGTCACACACAACCAACTGAAAAAGACTAGAGGGATTAGTACAA ACTCCTCTTATACAGAAGGCAAATCTGAGGTTCCACAGAAGTCTGGAACCAAGACTATTCAGTTGGTTAAATAAAGAGGTTAGTCTAGAC TGGGCCTGCTCATTCTAGGTCACCACATTTTCCATCTCCAAATAGCCAGGCCCTCTCTCCCTCAAGAAATGCCCAGATGTAGAAATTCAT CAGTGCCTATTGGTCTTCCAGAATTTTCCATCTTCCGTATCTCCCAGGCATGAGACTACCAAGTTTGTTTGTTTTCTTTCCAATTTGGGA ATTTATACTTCAGTATGGTTTCAACGCAGTTATGTTTCCAGAGAACATCTAGAAGTGGCTGGAAACCAGAAGCTGGGGATTCCAGGGACC CCACTTAGTGCTCTATTTCCTTTATAGGTTTTATTTCTGGTCATAGAGAGAGAAGGACCTTTGACTTTTTCTTCGTTGAGGCTTCTGAGG AGGAAAAACAAACCTAAAATAGAAATACAGTCAGCCTTTCAAATCCATGGGTTCTGTGTCCGTGGATTCAACCAACCTTGGATCAAAAAT ATTTGAAAAAAAATCTACAAAGTTTCAAAAAGCAAAACTTGAATTTGCTGCATGCCAAGAAGTATGTTGAATTCATGTAAATGAAGTGAT GTGTAGGCATTGTATTAGATATTATAAGAAATCTAGAAATGATTTAAAGCATACAGGAGGATGTGCATAGGTTATATGCAAATACTATGC TATTTTATATATGGGACTTGAGCATTTGTGGATTTTGATACTGGGGGATCCTGGAACCAATCCCCCATGGATACCAAAGTACGACTGTAG TTATCTATTTTTTACATACTTATTATTACCACCATGCTCAGTAAGTCCATTTTTGCATGGAATATGGAGCCTTAAAACATGTCATGAATT TGGAGTCCCTGGCACATAAATCTACCTTCAAATCAGAGGTCCTTAATGATGCCTAAACATACAGTAAAATTAGAATCAGAAATACTTCTT TAAAAAATATTCAAAATGTGTTTGTTTCCCATGGGATTATTCTCTATCCCACACGAATGTAAAAAAATCCACATTAATGATCCATTTAAG TATAGTTTTATTGGGTCCTTTTCTAATGATTAAAGGTTCTTTCTCAATTTCATTCCTCAGTCCTGCAAGTAAGGACTCATACTGAAGAGT ACTGAAACAAGGACTTCTTGTCAGAAACAGCTTCTGGAATCTTGGGTTTTGTTTTTGTTTTTTGACAAAATACACTATTGGCCATGTCCA TCACGAGAGTGTTTGTAGTAATTAATTACCTTGTACAGGACCTGGCACTTAGTAGCATTCTTCAAATGTTCCCTCAGTGATCCTTTTACT CTCCTTGTCACTTATTTGGGAGAAATAGGGGCACGTGAGATAAGAAGAAGAATAATTTTGATGTTGGTATGCTTGCCCTGTTACTTATAG ACAGTCTTTGTCATAGGCAAACTTGAATTTGATTTAAAATAGGGCTGGGAAAAATATTCAATAACTGTAAGCCCCCTTTTGGATGCCAAA CTTAGAATTTTGTACATTCTCTGATGAACAAGCATTTAGATCGTAACATGGTAAAGCCTATTACCAGCCAATGTTGTTAGCATCTTTGTA TGCACATCACTGTTTGTGCAATATATGAATATTTTGTTGCATTGTATTCTTATATAAAAATAAGTAGAAAACATAAAATTGAAATTGCTG >In-frame_BLNK_ENST00000427367_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_4093nt AAGTTTTACTTCTCCCTAGAGCAGGGGTGTTTGCCAGCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGA GGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAAT GGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGG AATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAAGA GGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAGAA CGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATAGA CAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACCTC CACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTCCC CGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGTAC ATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATGAC CAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTGGC CAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAAGT TTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGGGA CAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAGCT GGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAGCA GGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACGGT CCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGGAC GGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTCAG TGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGATGG GACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCTCC TCCACCTGTTCCACCCAGAGGACGCTGATTCCACCTCCTAAAACCTGCCTACTTCAGGACTTTAAGACTCACAGTCTTCAGCCTGTTAAT GATGTCTTCATGTTGAGTTTTATAGCATGACTGTTGACCTTAAGATCCATTCTCATTGCTGATAATGCTGCAGCCCTGCTGGTTTGGGCT TGCCTCGAAGATTTTATTAAGGCACGAAGAAGTGAAAAACTAAGGGCTTCATTCACCATCACCAAGTATATCGAACCATATACTTGTTTG CCAAAAGGATGAAGACTTAATCGAAATACTTACCTCTAATTTGCCATATCAGAAGCCTAAAAAGAATGATCATAAATGTACTTCACCAGT GATTTTACTGAAATGCACTTATATTAGTCTTTATGTATTTGCTAGTTCAGCCTGATTTCTAGAAGAGGTTATAGTGTGAGACTTGTAGTA TTCAAGTAAGATAAGTGACCTAATTTTAAAATAATTCTTCTACTTTTCTGTATATTCAGCAGGGTATTTAAGTGCTAGGGCTGGTCACAC ACAACCAACTGAAAAAGACTAGAGGGATTAGTACAAACTCCTCTTATACAGAAGGCAAATCTGAGGTTCCACAGAAGTCTGGAACCAAGA CTATTCAGTTGGTTAAATAAAGAGGTTAGTCTAGACTGGGCCTGCTCATTCTAGGTCACCACATTTTCCATCTCCAAATAGCCAGGCCCT CTCTCCCTCAAGAAATGCCCAGATGTAGAAATTCATCAGTGCCTATTGGTCTTCCAGAATTTTCCATCTTCCGTATCTCCCAGGCATGAG ACTACCAAGTTTGTTTGTTTTCTTTCCAATTTGGGAATTTATACTTCAGTATGGTTTCAACGCAGTTATGTTTCCAGAGAACATCTAGAA GTGGCTGGAAACCAGAAGCTGGGGATTCCAGGGACCCCACTTAGTGCTCTATTTCCTTTATAGGTTTTATTTCTGGTCATAGAGAGAGAA GGACCTTTGACTTTTTCTTCGTTGAGGCTTCTGAGGAGGAAAAACAAACCTAAAATAGAAATACAGTCAGCCTTTCAAATCCATGGGTTC TGTGTCCGTGGATTCAACCAACCTTGGATCAAAAATATTTGAAAAAAAATCTACAAAGTTTCAAAAAGCAAAACTTGAATTTGCTGCATG CCAAGAAGTATGTTGAATTCATGTAAATGAAGTGATGTGTAGGCATTGTATTAGATATTATAAGAAATCTAGAAATGATTTAAAGCATAC AGGAGGATGTGCATAGGTTATATGCAAATACTATGCTATTTTATATATGGGACTTGAGCATTTGTGGATTTTGATACTGGGGGATCCTGG AACCAATCCCCCATGGATACCAAAGTACGACTGTAGTTATCTATTTTTTACATACTTATTATTACCACCATGCTCAGTAAGTCCATTTTT GCATGGAATATGGAGCCTTAAAACATGTCATGAATTTGGAGTCCCTGGCACATAAATCTACCTTCAAATCAGAGGTCCTTAATGATGCCT AAACATACAGTAAAATTAGAATCAGAAATACTTCTTTAAAAAATATTCAAAATGTGTTTGTTTCCCATGGGATTATTCTCTATCCCACAC GAATGTAAAAAAATCCACATTAATGATCCATTTAAGTATAGTTTTATTGGGTCCTTTTCTAATGATTAAAGGTTCTTTCTCAATTTCATT CCTCAGTCCTGCAAGTAAGGACTCATACTGAAGAGTACTGAAACAAGGACTTCTTGTCAGAAACAGCTTCTGGAATCTTGGGTTTTGTTT TTGTTTTTTGACAAAATACACTATTGGCCATGTCCATCACGAGAGTGTTTGTAGTAATTAATTACCTTGTACAGGACCTGGCACTTAGTA GCATTCTTCAAATGTTCCCTCAGTGATCCTTTTACTCTCCTTGTCACTTATTTGGGAGAAATAGGGGCACGTGAGATAAGAAGAAGAATA ATTTTGATGTTGGTATGCTTGCCCTGTTACTTATAGACAGTCTTTGTCATAGGCAAACTTGAATTTGATTTAAAATAGGGCTGGGAAAAA TATTCAATAACTGTAAGCCCCCTTTTGGATGCCAAACTTAGAATTTTGTACATTCTCTGATGAACAAGCATTTAGATCGTAACATGGTAA AGCCTATTACCAGCCAATGTTGTTAGCATCTTTGTATGCACATCACTGTTTGTGCAATATATGAATATTTTGTTGCATTGTATTCTTATA >In-frame_BLNK_ENST00000413476_chr10_97976409_-_PIK3AP1_ENST00000339364_chr10_98388250_-_4093nt AAGTTTTACTTCTCCCTAGAGCAGGGGTGTTTGCCAGCAGCCTGCACTCTCAGAAATCAGACTTGAGTGGCCGGAACCCTTGAGACCAGA GGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACAGTTATTCGTGTCTCTTACAATTACCAAACAGAAT GGACAAGCTTAATAAAATAACCGTCCCCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGG AATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTACGCTTCAGAGAGCCCTGCTGACGAAGA GGAGCAGTGGTCCGATGACTTTGACAGCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAGAA CGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTGCCCTTCGCCAGAGGCGAGTATATAGA CAATCGATCAAGCCAGAGGCATTCCCCACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACCTC CACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTTGAGGATGAGGCTGATTATGTGGTCCC CGTGGAAGATAATGATGAAAACTATATTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGATGTTGAAATGCTTCAGGCCAGTAC ATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAAGGCAACAGCATGGGAATGAC CAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATCACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTGGC CAGCAGGCCCCCTGTCCCAGTGCCCAGACCAGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAAGT TTTTGCAGAAAAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGACCATGGAGGGA CAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCAGCTTATCACCCTCCAGGAGCAGGTGAAGCT GGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAAGAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAGCA GGAAAATCTTAAACGGCTAAGAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACGGT CCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAAAGTGTCATTCCCCCTAGGAC GGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAAGTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTCAG TGTGAGCAGCGGGATGGAAGGGGACAACGAGGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGATGG GACACCCACCATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCTTCCATCCTCC TCCACCTGTTCCACCCAGAGGACGCTGATTCCACCTCCTAAAACCTGCCTACTTCAGGACTTTAAGACTCACAGTCTTCAGCCTGTTAAT GATGTCTTCATGTTGAGTTTTATAGCATGACTGTTGACCTTAAGATCCATTCTCATTGCTGATAATGCTGCAGCCCTGCTGGTTTGGGCT TGCCTCGAAGATTTTATTAAGGCACGAAGAAGTGAAAAACTAAGGGCTTCATTCACCATCACCAAGTATATCGAACCATATACTTGTTTG CCAAAAGGATGAAGACTTAATCGAAATACTTACCTCTAATTTGCCATATCAGAAGCCTAAAAAGAATGATCATAAATGTACTTCACCAGT GATTTTACTGAAATGCACTTATATTAGTCTTTATGTATTTGCTAGTTCAGCCTGATTTCTAGAAGAGGTTATAGTGTGAGACTTGTAGTA TTCAAGTAAGATAAGTGACCTAATTTTAAAATAATTCTTCTACTTTTCTGTATATTCAGCAGGGTATTTAAGTGCTAGGGCTGGTCACAC ACAACCAACTGAAAAAGACTAGAGGGATTAGTACAAACTCCTCTTATACAGAAGGCAAATCTGAGGTTCCACAGAAGTCTGGAACCAAGA CTATTCAGTTGGTTAAATAAAGAGGTTAGTCTAGACTGGGCCTGCTCATTCTAGGTCACCACATTTTCCATCTCCAAATAGCCAGGCCCT CTCTCCCTCAAGAAATGCCCAGATGTAGAAATTCATCAGTGCCTATTGGTCTTCCAGAATTTTCCATCTTCCGTATCTCCCAGGCATGAG ACTACCAAGTTTGTTTGTTTTCTTTCCAATTTGGGAATTTATACTTCAGTATGGTTTCAACGCAGTTATGTTTCCAGAGAACATCTAGAA GTGGCTGGAAACCAGAAGCTGGGGATTCCAGGGACCCCACTTAGTGCTCTATTTCCTTTATAGGTTTTATTTCTGGTCATAGAGAGAGAA GGACCTTTGACTTTTTCTTCGTTGAGGCTTCTGAGGAGGAAAAACAAACCTAAAATAGAAATACAGTCAGCCTTTCAAATCCATGGGTTC TGTGTCCGTGGATTCAACCAACCTTGGATCAAAAATATTTGAAAAAAAATCTACAAAGTTTCAAAAAGCAAAACTTGAATTTGCTGCATG CCAAGAAGTATGTTGAATTCATGTAAATGAAGTGATGTGTAGGCATTGTATTAGATATTATAAGAAATCTAGAAATGATTTAAAGCATAC AGGAGGATGTGCATAGGTTATATGCAAATACTATGCTATTTTATATATGGGACTTGAGCATTTGTGGATTTTGATACTGGGGGATCCTGG AACCAATCCCCCATGGATACCAAAGTACGACTGTAGTTATCTATTTTTTACATACTTATTATTACCACCATGCTCAGTAAGTCCATTTTT GCATGGAATATGGAGCCTTAAAACATGTCATGAATTTGGAGTCCCTGGCACATAAATCTACCTTCAAATCAGAGGTCCTTAATGATGCCT AAACATACAGTAAAATTAGAATCAGAAATACTTCTTTAAAAAATATTCAAAATGTGTTTGTTTCCCATGGGATTATTCTCTATCCCACAC GAATGTAAAAAAATCCACATTAATGATCCATTTAAGTATAGTTTTATTGGGTCCTTTTCTAATGATTAAAGGTTCTTTCTCAATTTCATT CCTCAGTCCTGCAAGTAAGGACTCATACTGAAGAGTACTGAAACAAGGACTTCTTGTCAGAAACAGCTTCTGGAATCTTGGGTTTTGTTT TTGTTTTTTGACAAAATACACTATTGGCCATGTCCATCACGAGAGTGTTTGTAGTAATTAATTACCTTGTACAGGACCTGGCACTTAGTA GCATTCTTCAAATGTTCCCTCAGTGATCCTTTTACTCTCCTTGTCACTTATTTGGGAGAAATAGGGGCACGTGAGATAAGAAGAAGAATA ATTTTGATGTTGGTATGCTTGCCCTGTTACTTATAGACAGTCTTTGTCATAGGCAAACTTGAATTTGATTTAAAATAGGGCTGGGAAAAA TATTCAATAACTGTAAGCCCCCTTTTGGATGCCAAACTTAGAATTTTGTACATTCTCTGATGAACAAGCATTTAGATCGTAACATGGTAA AGCCTATTACCAGCCAATGTTGTTAGCATCTTTGTATGCACATCACTGTTTGTGCAATATATGAATATTTTGTTGCATTGTATTCTTATA |
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FusionGenePPI for BLNK_PIK3AP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BLNK | NCK1, VAV1, GRB2, MAP4K1, SH3KBP1, CD79A, CRKL, BTK, CD72, PTPN6, CD2AP, CAPZA1, CAPZA2, CAPZB, HSPA4, HSPH1, MYBPC3, CLEC17A, DOK3, NCK2, TLN1, LYN, SYK, PLCG2, VAV3, MAP2K4, PPP2R2C, AIFM1, WDR81, CBL, PLCG1, GRAP2, ERBB2 | PIK3AP1 | ITSN1, ITSN2, GRB2, NCK2, WNT7A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BLNK_PIK3AP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BLNK_PIK3AP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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