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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 41965

FusionGeneSummary for WHSC1L1_ADAM18

check button Fusion gene summary
Fusion gene informationFusion gene name: WHSC1L1_ADAM18
Fusion gene ID: 41965
HgeneTgene
Gene symbol

WHSC1L1

ADAM18

Gene ID

54904

8749

Gene namenuclear receptor binding SET domain protein 3ADAM metallopeptidase domain 18
SynonymsKMT3F|KMT3G|WHISTLE|WHSC1L1|pp14328ADAM27|tMDCIII
Cytomap

8p11.23

8p11.22

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase NSD3WHSC1-like 1 isoform 9 with methyltransferase activity to lysineWolf-Hirschhorn syndrome candidate 1-like 1nuclear SET domain-containing protein 3protein whistledisintegrin and metalloproteinase domain-containing protein 18a disintegrin and metalloproteinase domain 18transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III
Modification date2018051920180329
UniProtAcc

Q9Y3Q7

Ensembl transtripts involved in fusion geneENST00000317025, ENST00000433384, 
ENST00000527502, ENST00000316985, 
ENST00000525081, 		ENST00000265707, 
ENST00000379866, ENST00000520772, 
ENST00000541111, ENST00000523755, 
Fusion gene scores* DoF score19 X 10 X 10=19006 X 5 X 5=150
# samples 226
** MAII scorelog2(22/1900*10)=-3.11042398969365
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: WHSC1L1 [Title/Abstract] AND ADAM18 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWHSC1L1

GO:0016571

histone methylation

16682010


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVCOADTCGA-D5-6926-01AWHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000317025ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000317025ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000317025ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000317025ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000317025ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
In-frameENST00000433384ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000433384ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000433384ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000433384ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000433384ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
In-frameENST00000527502ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
Frame-shiftENST00000527502ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000527502ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-intronENST00000527502ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
5CDS-3UTRENST00000527502ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000316985ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000316985ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000316985ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000316985ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3UTRENST00000316985ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000525081ENST00000265707WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3CDSENST00000525081ENST00000379866WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000525081ENST00000520772WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-intronENST00000525081ENST00000541111WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+
intron-3UTRENST00000525081ENST00000523755WHSC1L1chr8

38137058

-ADAM18chr8

39587417

+

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FusionProtFeatures for WHSC1L1_ADAM18


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
WHSC1L1

ADAM18

Q9Y3Q7

Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. Sperm surface membrane protein that may be involved inspermatogenesis and fertilization. This is a non catalyticmetalloprotease-like protein (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241033_106912531438Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231033_106912041389Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241093_114312531438DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124270_33312531438DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124960_102212531438DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231093_114312041389DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023270_33312041389DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023960_102212041389DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124701_74812531438Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124749_80512531438Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-2124862_95512531438Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023701_74812041389Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023749_80512041389Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-2023862_95512041389Zinc fingerPHD-type 3
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06480_622-13183Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06184_381-13183DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06390_479-13183DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06620_654-13183DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719709_739701716Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06177_687-13183Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06709_739-13183Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST00000520772+06688_708-13183TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101033_1069-173646Coiled coilOntology_term=ECO:0000255
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101093_1143-173646DomainAWS
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101145_1262-173646DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101269_1285-173646DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110270_333-173646DomainPWWP 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110960_1022-173646DomainPWWP 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241145_126212531438DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241269_128512531438DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231145_126212041389DomainSET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231269_128512041389DomainPost-SET
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-1101321_1368-173646Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110701_748-173646Zinc fingerPHD-type 1
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110749_805-173646Zinc fingerPHD-type 2
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000316985-110862_955-173646Zinc fingerPHD-type 3
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000317025-21241321_136812531438Zinc fingerPHD-type 4%3B atypical
HgeneWHSC1L1chr8:38137058chr8:39587417ENST00000433384-20231321_136812041389Zinc fingerPHD-type 4%3B atypical
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820480_622725740Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719480_622701716Compositional biasNote=Cys-rich
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820184_381725740DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820390_479725740DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820620_654725740DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719184_381701716DomainPeptidase M12B
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719390_479701716DomainDisintegrin
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719620_654701716DomainNote=EGF-like
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820177_687725740Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820709_739725740Topological domainCytoplasmic
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719177_687701716Topological domainExtracellular
TgeneADAM18chr8:38137058chr8:39587417ENST00000265707+1820688_708725740TransmembraneHelical
TgeneADAM18chr8:38137058chr8:39587417ENST00000379866+1719688_708701716TransmembraneHelical


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FusionGeneSequence for WHSC1L1_ADAM18


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_WHSC1L1_ENST00000317025_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_1267aa
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF
VNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAVIHPLYQ

>In-frame_WHSC1L1_ENST00000433384_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_1218aa
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGGRLLCCESCPASFHPECLSIEMPEGCWNC
NDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKK
ALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCP
AGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYS

>In-frame_WHSC1L1_ENST00000527502_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_1256aa
MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNGYPSSISVYETQTKYQSYN
QYPNGSANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV
GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRH
SQRRHTSAEEEEPPPVKIAWKTAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKSTEVVPKKKIKKEQVETVPQATVKTGLQKGASEISDSCKPL
KKRSRASTDVEMTSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHK
ASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHSKRSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAE
LMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQG
LKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKPPPYKHIKANK
VIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEF


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_WHSC1L1_ENST00000317025_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_3803nt
ATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAG
GAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCA
GCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAAT
CAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGA
CCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCA
CCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTA
CAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAG
CGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAA
GAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTT
GGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATT
AACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTAT
AAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGA
CCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTAT
ACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGA
CGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACAT
AGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCA
GCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAG
AATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAA
GACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGC
TCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAA
AAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTA
AAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGAC
CTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTG
TCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAG
TGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCAC
CCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGC
AAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAA
GCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTA
TCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGA
GGGCTGATAGTTCAGGACCATTCAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTGAG
TTGATGAAATTACCTATGATTCCTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCA
GCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTAC
AAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGC
CTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTT
GAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAA
TTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAA
GTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTG
GAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACA
AAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTT
GTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTAT
ATGTTAACTGTTACCAAGGACCGTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGT
GAAACACAAAAGTGGACAGTGAATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAG

>In-frame_WHSC1L1_ENST00000433384_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_3656nt
ATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAG
GAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCA
GCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAAT
CAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGA
CCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCA
CCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTA
CAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAG
CGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAA
GAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTT
GGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATT
AACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTAT
AAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGA
CCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTAT
ACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGA
CGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACAT
AGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCA
GCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAG
AATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAA
GACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGC
TCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAA
AAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTA
AAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGAC
CTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTG
TCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAG
TGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCAC
CCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGC
AAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAA
GCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTA
TCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGA
GGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGT
AATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGC
AACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTAC
TGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAG
GCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAA
CCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAAC
TGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCA
GCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTC
AGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAG
CGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCAAGGACCGTATAATTGATGCCGGCCCAAAAGGAAATTATTCT
CGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGAATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGT

>In-frame_WHSC1L1_ENST00000527502_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_3770nt
ATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAG
GAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCA
GCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAAT
CAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGA
CCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCA
CCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTA
CAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAG
CGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAA
GAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTT
GGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATT
AACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTAT
AAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGA
CCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTAT
ACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGA
CGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACAT
AGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCA
GCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAG
AATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAA
GACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGC
TCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAA
AAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTA
AAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGAC
CTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTG
TCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAG
TGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCAC
CCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGC
AAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAA
GCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTA
TCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGA
GGGCTGATAGTTCAGGACCATTCAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTGAG
TTGATGAAATTACCTATGATTCCTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCA
GCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTAC
AAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGC
CTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTT
GAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAA
TTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAA
GTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTG
GAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACA
AAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTT
GTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGACCGTATAATTGAT
GCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGAATGGAGATGTT


* Fusion transcript sequences (Full-length transcript).
>In-frame_WHSC1L1_ENST00000317025_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_4444nt
GGGGGCTTTGTGCGCGGCGGCGGCGGGAGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCG
GAGAGGCGTGCGAATTCCGAGCCGAGCGCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCG
GCGCGGCGACCCCCGTCCCTCGGCCTCCCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGT
GGCCCTCCTCAGTGCCGGCCGCCATGGCAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGC
CTCCTCCTCGCGCGGCCCCAGCGGCTGCCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGG
GGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCA
TGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACA
GTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTC
CACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCA
ATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAAC
CTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAA
CCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAAT
CAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCA
AATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAG
CCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGG
TGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAAT
ATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAG
AATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGT
GGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAAC
AGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATA
CTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTG
CGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAG
GGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAAT
TTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACAC
CAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGA
GAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTC
CTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAA
CTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGC
AAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGA
GTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGG
AGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGT
CTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTG
AATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGA
GATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTA
GTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGGCTGATAGTTCAGGACCATT
CAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTGAGTTGATGAAATTACCTATGATTC
CTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGGAATGCC
TAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGGTCAAAT
TGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGGGGGACT
TCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCTTTGCTG
AAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAGAAAGTA
AAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGCAGATCC
AGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGAACAGAA
TGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTGATGCAG
AGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCGGTGAAT
TAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCAAGGACC
GTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGA
ATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTA
ATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGT

>In-frame_WHSC1L1_ENST00000433384_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_4270nt
AGAGGCGGCGGCGGCGGCCAGCACGGAGGCGGAGGCCGAGGGGGCTGTGCACAGGTCGCCGCGGAGAGGCGTGCGAATTCCGAGCCGAGC
GCCGAGGACCGTGCTACCCAGGCCGGGCTGCCAGCCGCAGGCTCCTCTCTGGCAGCAGCGGCGGCGCGGCGACCCCCGTCCCTCGGCCTC
CCCTTCCCATCCCACCTCCCGAGCCTTCCTCTTCCCGCAGCACGCCCGGCCCGGCCCGGCCGTGGCCCTCCTCAGTGCCGGCCGCCATGG
CAGAGGCGTCCGGCGCGGGGAAAATCTAGCCCGGGGATTTCATGCGGCCTAGCTCGGTTCCGCCTCCTCCTCGCGCGGCCCCAGCGGCTG
CCCGCACCCCAGCCCCACTCCGGGCCTCCGTGTCTCTCCTGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCC
CGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAACAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTC
AGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTCAGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGA
CACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACCCAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAA
TCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATAATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTA
GCCCCACTGACTATTATCATTCAGAAATTCCAAACACAAGACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTC
CTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCTCACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAAT
TGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAGTACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGA
GGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAGAGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGAC
CAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGGAAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTG
TTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGGTTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTA
TGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAATTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGC
CAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGTATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAG
CCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCCGACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGA
AAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGTATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAA
AAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCCGACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGG
AGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGACATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTA
AAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTACCAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACA
TGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTCAGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAA
AGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGCAAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGC
AGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAGGCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAAT
CAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCAAAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTAC
AGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTCTAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCAT
ACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTGACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAG
ATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTTTGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTT
GTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAGAGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTG
ATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGCACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTG
TTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCCGCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGC
ACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACAAAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATC
ACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAGTATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATT
CTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCAGAGGTGGAAGATTGCTCTGCTGTGAATCGTGCCCAGCTTCCTTCCACCCGG
AATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATTACAAGCAGATTGTTTGGG
TCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGGGCCTTAAACATGACTTGG
GGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATGTTGAAGGAGACAAAAGCT
TTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGGAATTGAAAGCACAAAGAG
AAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACAAAGTAATAGGAAAGGTGC
AGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCTTGGAATCGGAGTGCCTGA
ACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTACAAAGAGACTATACCCTG
ATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAATTTGTAAATGAATACGTCG
GTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGTAACTAATTTTTATATGTTAACTGTTACCA
AGGACCGTATAATTGATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGA
CAGTGAATGGAGATGTTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGG
ACATTAATATTGCACAGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGT

>In-frame_WHSC1L1_ENST00000527502_chr8_38137058_-_ADAM18_ENST00000265707_chr8_39587417_+_3985nt
TGTGATCGCACTGACACGGCCGGGGGGTTAGAATGGAACAAACTGAAGGCCCGATGAGAGAAAGGGAAAGTTAAGGATGCTGGAGCAGAA
CAATGGATTTCTCTTTCTCTTTCATGCAAGGGATCATGGGAAACACAATTCAGCAACCACCTCAACTCATTGACTCCGCCAACATCCGTC
AGGAGGATGCCTTTGATAACAACAGTGACATTGCTGAAGATGGTGGCCAGACACCATATGAAGCTACTTTGCAGCAAGGCTTTCAGTACC
CAGCTACAACAGAAGATCTTCCTCCACTCACAAATGGGTATCCATCATCAATCAGTGTGTATGAAACTCAAACCAAATACCAGTCATATA
ATCAGTATCCTAATGGGTCAGCCAATGGCTTTGGTGCAGTTAGAAACTTTAGCCCCACTGACTATTATCATTCAGAAATTCCAAACACAA
GACCACATGAAATTCTGGAAAAACCTTCCCCTCCACAGCCACCACCTCCTCCTTCGGTACCACAAACTGTGATTCCAAAGAAGACTGGCT
CACCTGAAATTAAACTAAAAATAACCAAAACTATCCAGAATGGCAGGGAATTGTTTGAGTCTTCCCTTTGTGGAGACCTTTTAAATGAAG
TACAGGCAAGTGAGCACACGAAATCAAAGCATGAAAGCAGAAAAGAAAAGAGGAAAAAAAGCAACAAGCATGACTCATCAAGATCTGAAG
AGCGCAAGTCACACAAAATCCCCAAATTAGAACCAGAGGAACAAAATAGACCAAATGAGAGGGTTGACACTGTATCAGAAAAACCAAGGG
AAGAACCAGTACTAAAAGAGGAAGCCCCAGTTCAGCCAATACTATCTTCTGTTCCAACAACGGAAGTGTCCACTGGTGTTAAGTTTCAGG
TTGGCGATCTTGTGTGGTCCAAGGTGGGAACCTATCCTTGGTGGCCTTGTATGGTTTCAAGTGATCCCCAGCTTGAGGTTCATACTAAAA
TTAACACAAGAGGTGCCCGAGAATATCATGTCCAGTTTTTTAGCAACCAGCCAGAGAGGGCGTGGGTTCATGAAAAACGGGTACGAGAGT
ATAAAGGTCATAAACAGTATGAAGAATTACTGGCTGAGGCAACCAAACAAGCCAGCAATCACTCTGAGAAACAAAAGATTCGGAAACCCC
GACCTCAGAGAGAACGTGCTCAGTGGGATATTGGCATTGCCCATGCAGAGAAAGCATTGAAAATGACTCGAGAAGAAAGAATAGAACAGT
ATACTTTTATTTACATTGATAAACAGCCTGAAGAGGCTTTATCCCAAGCAAAAAAGAGTGTTGCCTCCAAAACCGAAGTTAAAAAAACCC
GACGACCAAGATCTGTGCTGAATACTCAGCCAGAACAGACCAATGCAGGGGAGGTGGCCTCCTCACTCTCAAGTACTGAAATTCGGAGAC
ATAGCCAGAGGCGGCACACAAGTGCGGAAGAGGAAGAGCCACCGCCTGTTAAAATAGCCTGGAAAACTGCGGCAGCAAGGAAATCCTTAC
CAGCTTCCATTACGATGCACAAAGGGAGCCTGGATTTGCAGAAGTGTAACATGTCTCCAGTTGTGAAAATTGAACAAGTGTTTGCTCTTC
AGAATGCTACAGGGGATGGGAAATTTATCGATCAATTTGTTTATTCAACAAAGGGAATTGGTAACAAAACAGAAATAAGTGTCAGGGGGC
AAGACAGGCTTATAATTTCTACACCAAACCAGAGAAATGAAAAGCCAACGCAGAGTGTATCATCTCCTGAAGCAACATCTGGTTCTACAG
GCTCAGTAGAAAAGAAGCAACAGAGAAGATCAATTAGAACTCGTTCTGAATCAGAGAAATCCACTGAGGTTGTGCCAAAGAAGAAGATCA
AAAAGGAGCAGGTTGAAACAGTTCCTCAGGCTACAGTGAAGACTGGATTACAGAAAGGTGCCAGCGAGATTTCAGATTCCTGTAAACCTC
TAAAGAAAAGGAGTCGCGCCTCAACTGATGTAGAAATGACTAGTTCAGCATACAGAGACACATCTGACTCCGATTCTAGAGGACTGAGTG
ACCTGCAGGTAGGCTTTGGAAAGCAAGTAGATAGCCCTTCAGCTACTGCAGATGCAGACGTTTCTGATGTGCAGTCCATGGATTCAAGTT
TGTCGAGAAGAGGCACTGGAATGAGTAAGAAGGACACTGTATGTCAGATTTGTGAAAGCTCTGGTGACTCTCTGATTCCTTGTGAGGGAG
AGTGCTGCAAACACTTTCACCTGGAGTGCCTGGGATTGGCATCACTTCCTGATAGCAAGTTCATCTGCATGGAATGTAAAACTGGGCAGC
ACCCATGTTTTTCGTGTAAAGTGTCTGGTAAAGATGTGAAGCGTTGTTCTGTTGGTGCTTGTGGGAAATTTTATCATGAAGCCTGTGTCC
GCAAATTCCCCACTGCCATCTTTGAATCAAAAGGATTCCGCTGTCCTCAGCACTGCTGCTCTGCCTGCTCTATGGAGAAAGATATCCACA
AAGCAAGTAAAGGCCGCATGATGAGATGTTTAAGATGTCCAGTTGCCTATCACTCTGGAGATGCTTGCATTGCGGCCGGAAGCATGTTAG
TATCCTCCTACATTCTCATCTGTAGTAATCATTCCAAACGGAGCAGTAATTCTTCTGCTGTAAATGTAGGCTTTTGTTTCGTTTGTGCCA
GAGGGCTGATAGTTCAGGACCATTCAGACCCCATGTTCAGTTCATATGCCTATAAGTCCCACTACCTACTGAATGAATCAAATCGTGCTG
AGTTGATGAAATTACCTATGATTCCTTCTTCGTCAGCTTCCAAAAAGAAATGTGAGAAAGGTGGAAGATTGCTCTGCTGTGAATCGTGCC
CAGCTTCCTTCCACCCGGAATGCCTAAGCATAGAAATGCCAGAAGGCTGCTGGAATTGTAATGACTGTAAAGCTGGCAAGAAACTACATT
ACAAGCAGATTGTTTGGGTCAAATTGGGAAATTACAGATGGTGGCCAGCAGAGATCTGCAACCCCAGGTCTGTGCCACTGAACATCCAGG
GCCTTAAACATGACTTGGGGGACTTCCCTGTATTCTTCTTTGGTTCTCATGACTACTACTGGGTACACCAGGGCAGAGTGTTCCCTTATG
TTGAAGGAGACAAAAGCTTTGCTGAAGGGCAGACTAGTATTAACAAGACCTTCAAAAAGGCACTGGAAGAAGCTGCAAAACGTTTCCAGG
AATTGAAAGCACAAAGAGAAAGTAAAGAAGCCCTAGAGATTGAAAAAAACTCAAGAAAACCCCCTCCCTACAAACACATCAAAGCTAACA
AAGTAATAGGAAAGGTGCAGATCCAGGTTGCTGACCTGTCAGAGATTCCCCGCTGTAACTGCAAGCCAGCTGATGAAAACCCTTGTGGCT
TGGAATCGGAGTGCCTGAACAGAATGTTGCAGTATGAATGCCACCCGCAGGTGTGCCCAGCTGGAGATCGTTGTCAGAACCAGTGCTTTA
CAAAGAGACTATACCCTGATGCAGAGATCATCAAAACGGAGCGGAGAGGCTGGGGCCTCAGGACCAAAAGGAGCATTAAGAAGGGTGAAT
TTGTAAATGAATACGTCGGTGAATTAATTGATGAAGAAGAATGCAGATTGCGAATCAAGCGAGCCCACGAGAACAGTGACCGTATAATTG
ATGCCGGCCCAAAAGGAAATTATTCTCGCTTCATGAACCACAGTTGTAATCCCAACTGTGAAACACAAAAGTGGACAGTGAATGGAGATG
TTCGAGTGGGACTATTTGCTCTCTGTGATATTCCTGCAGTAATTCATCCGTTGTATCAGAAAGCGATGACGTGGGACATTAATATTGCAC
AGAACTTCCATAGCAAATAACCTAAAGGAACGAATGTGCTTTATTTATAACCTTACGTTATCCCCAATGCATTGTAAATGTCAAACTTTT


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FusionGenePPI for WHSC1L1_ADAM18


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
WHSC1L1CBX3, KDM1B, CCNT1, BRD4, H2AFY, CRNN, BRD9, SMARCC1, BCL7C, SMARCA4, BCL7A, SS18L1, SMARCA2, DAXX, HOXC4, MNDA, SLU7, DOCK7, ETV3, GLYR1, H3F3C, HIST1H1A, SEPT6, SPAG8, STAC3, UBE2I, ZNF557, HIST3H3, MLLT6, CBX5, AKT1, ATM, BCAR3, CASP8, CDKN2A, CHEK2, ESR1, FGFR4, PAX2, PPM1D, RAD51, RB1CC1, TGFB1, HIST1H2BG, LSM3, YEATS4, BRD2, HIST1H3A, HIST1H4A, BPTF, BOD1L1, CHD8, CDC14BADAM18


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for WHSC1L1_ADAM18


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for WHSC1L1_ADAM18


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource