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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 41948

FusionGeneSummary for WDSUB1_FYTTD1

check button Fusion gene summary
Fusion gene informationFusion gene name: WDSUB1_FYTTD1
Fusion gene ID: 41948
HgeneTgene
Gene symbol

WDSUB1

FYTTD1

Gene ID

151525

84248

Gene nameWD repeat, sterile alpha motif and U-box domain containing 1forty-two-three domain containing 1
SynonymsUBOX6|WDSAM1UIF
Cytomap

2q24.2

3q29

Type of geneprotein-codingprotein-coding
DescriptionWD repeat, SAM and U-box domain-containing protein 1UAP56-interacting factorforty-two-three domain-containing protein 1protein 40-2-3
Modification date2018051920180523
UniProtAcc

Q8N9V3

Q96QD9

Ensembl transtripts involved in fusion geneENST00000359774, ENST00000358147, 
ENST00000392796, ENST00000409990, 
ENST00000409124, 		ENST00000415708, 
ENST00000428395, ENST00000241502, 
ENST00000424384, ENST00000492360, 
Fusion gene scores* DoF score4 X 3 X 4=483 X 3 X 2=18
# samples 43
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: WDSUB1 [Title/Abstract] AND FYTTD1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-IE-A3OV-01AWDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000359774ENST00000415708WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000359774ENST00000428395WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000359774ENST00000241502WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000359774ENST00000424384WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-intronENST00000359774ENST00000492360WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
In-frameENST00000358147ENST00000415708WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000358147ENST00000428395WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000358147ENST00000241502WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000358147ENST00000424384WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-intronENST00000358147ENST00000492360WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
Frame-shiftENST00000392796ENST00000415708WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000392796ENST00000428395WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000392796ENST00000241502WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000392796ENST00000424384WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-intronENST00000392796ENST00000492360WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
Frame-shiftENST00000409990ENST00000415708WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409990ENST00000428395WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409990ENST00000241502WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409990ENST00000424384WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-intronENST00000409990ENST00000492360WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
In-frameENST00000409124ENST00000415708WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409124ENST00000428395WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409124ENST00000241502WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-5UTRENST00000409124ENST00000424384WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+
5CDS-intronENST00000409124ENST00000492360WDSUB1chr2

160132057

-FYTTD1chr3

197483297

+

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FusionProtFeatures for WDSUB1_FYTTD1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
WDSUB1

Q8N9V3

FYTTD1

Q96QD9


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-4710_47225385RepeatNote=WD 1
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47137_176225385RepeatNote=WD 4
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47178_228225385RepeatNote=WD 5
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-4752_91225385RepeatNote=WD 2
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-4795_134225385RepeatNote=WD 3
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-41110_47225477RepeatNote=WD 1
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411137_176225477RepeatNote=WD 4
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411178_228225477RepeatNote=WD 5
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-41152_91225477RepeatNote=WD 2
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-41195_134225477RepeatNote=WD 3
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-41110_47225477RepeatNote=WD 1
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411137_176225477RepeatNote=WD 4
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411178_228225477RepeatNote=WD 5
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-41152_91225477RepeatNote=WD 2
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-41195_134225477RepeatNote=WD 3
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-41110_47225477RepeatNote=WD 1
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411137_176225477RepeatNote=WD 4
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411178_228225477RepeatNote=WD 5
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-41152_91225477RepeatNote=WD 2
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-41195_134225477RepeatNote=WD 3
TgeneFYTTD1chr2:160132057chr3:197483297ENST00000415708+11026_448293MotifNote=UAP56-binding motif
TgeneFYTTD1chr2:160132057chr3:197483297ENST00000424384+0926_44-33252MotifNote=UAP56-binding motif

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47332_396225385DomainSAM
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47403_476225385DomainNote=U-box
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411332_396225477DomainSAM
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411403_476225477DomainNote=U-box
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411332_396225477DomainSAM
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411403_476225477DomainNote=U-box
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411332_396225477DomainSAM
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411403_476225477DomainNote=U-box
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47237_276225385RepeatNote=WD 6
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000358147-47279_318225385RepeatNote=WD 7
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411237_276225477RepeatNote=WD 6
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000359774-411279_318225477RepeatNote=WD 7
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411237_276225477RepeatNote=WD 6
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000392796-411279_318225477RepeatNote=WD 7
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411237_276225477RepeatNote=WD 6
HgeneWDSUB1chr2:160132057chr3:197483297ENST00000409990-411279_318225477RepeatNote=WD 7
TgeneFYTTD1chr2:160132057chr3:197483297ENST00000241502+0926_4434319MotifNote=UAP56-binding motif


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FusionGeneSequence for WDSUB1_FYTTD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_WDSUB1_ENST00000359774_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_510aa
MVKLIHTLADHGDDVNCCAFSFSLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLA
VMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCPHSEKAHD
LGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILDDIIKLNRKEGKKQNFPRLNRRLLQQSGAQQFRMRVRWGIQQNSG
FGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDKNIEQYFPVLKRKANLLRQNEGQRKPVAVLKRPSQLSRKNNI
PANFTRSGNKLNHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFL

>In-frame_WDSUB1_ENST00000358147_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_510aa
MVKLIHTLADHGDDVNCCAFSFSLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLA
VMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCPHSEKAHD
LGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILDDIIKLNRKEGKKQNFPRLNRRLLQQSGAQQFRMRVRWGIQQNSG
FGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDKNIEQYFPVLKRKANLLRQNEGQRKPVAVLKRPSQLSRKNNI
PANFTRSGNKLNHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFL

>In-frame_WDSUB1_ENST00000409124_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_510aa
MVKLIHTLADHGDDVNCCAFSFSLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLA
VMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCPHSEKAHD
LGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILDDIIKLNRKEGKKQNFPRLNRRLLQQSGAQQFRMRVRWGIQQNSG
FGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDKNIEQYFPVLKRKANLLRQNEGQRKPVAVLKRPSQLSRKNNI
PANFTRSGNKLNHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_WDSUB1_ENST00000359774_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1530nt
ATGGTGAAACTGATTCACACATTAGCTGATCATGGTGACGATGTCAACTGCTGTGCCTTCTCCTTTTCCCTCTTGGCTACTTGCTCCTTG
GACAAAACAATTCGCCTGTACTCGTTACGTGACTTTACTGAACTGCCACATTCTCCATTGAAGTTTCATACCTATGCTGTCCACTGCTGC
TGTTTCTCCCCTTCAGGACATATTTTGGCATCGTGTTCAACAGATGGTACCACTGTCCTATGGAATACTGAAAATGGACAGATGCTGGCA
GTGATGGAACAGCCTAGTGGCAGCCCTGTGAGGGTTTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCATCAGGGGCAGCTGATGGAACT
GTGGTTTTGTGGAATGCACAGTCATACAAATTATATAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCGGCATGTGCATTTTCTCCTAAT
GGAAGCTTCTTTGTCACTGGCTCCTCATGTGGTGATTTAACAGTGTGGGATGATAAAATGAGGTGTCCGCATAGTGAAAAAGCACATGAT
CTTGGAATTACCTGCTGCGATTTTTCTTCACAGCCAGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTTCGACTGGCATCATGTGGTCAG
GATTGCCAAGTCAAAATTTGGATTGTTTCTTTTACCCATATCTTAGATGATATCATCAAGTTGAATCGAAAGGAAGGGAAGAAGCAGAAT
TTTCCAAGACTAAATAGAAGACTCCTCCAGCAAAGTGGTGCCCAGCAATTCAGGATGAGAGTGCGATGGGGAATCCAACAGAATTCTGGT
TTTGGTAAGACTAGTCTGAATCGTAGAGGAAGAGTAATGCCTGGAAAGAGACGTCCTAATGGAGTTATCACTGGCCTTGCAGCTAGGAAA
ACGACTGGAATTCGAAAAGGAATTAGTCCTATGAATCGTCCACCTCTAAGTGACAAGAATATAGAACAATATTTTCCAGTGTTAAAAAGG
AAGGCAAACCTTCTGAGACAAAATGAAGGGCAGAGGAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAGCTAAGCAGAAAAAATAACATT
CCAGCTAATTTTACCAGGAGTGGAAATAAATTAAATCATCAGAAAGATACTCGTCAGGCAACTTTTCTTTTCAGAAGAGGCCTGAAGGTG
CAGGCCCAGTTGAATACAGAACAACTGCTAGACGATGTAGTAGCAAAGAGAACTCGTCAATGGCGGACTTCCACCACAAATGGAGGGATT
TTGACTGTATCTATTGACAATCCTGGAGCAGTGCAATGCCCAGTAACTCAGAAACCACGATTAACTCGTACTGCTGTACCTTCATTTTTA
ACAAAGCGGGAGCAAAGTGACGTCAAGAAAGTTCCTAAAGGTGTTCCCCTGCAGTTTGACATAAACAGTGTCGGAAAACAGACAGGGATG
ACGTTGAATGAGCGGTTTGGGATCCTGAAGGAACAAAGAGCCACTCTCACATACAACAAAGGGGGAAGCCGCTTTGTCACCGTGGGATAG

>In-frame_WDSUB1_ENST00000358147_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1530nt
ATGGTGAAACTGATTCACACATTAGCTGATCATGGTGACGATGTCAACTGCTGTGCCTTCTCCTTTTCCCTCTTGGCTACTTGCTCCTTG
GACAAAACAATTCGCCTGTACTCGTTACGTGACTTTACTGAACTGCCACATTCTCCATTGAAGTTTCATACCTATGCTGTCCACTGCTGC
TGTTTCTCCCCTTCAGGACATATTTTGGCATCGTGTTCAACAGATGGTACCACTGTCCTATGGAATACTGAAAATGGACAGATGCTGGCA
GTGATGGAACAGCCTAGTGGCAGCCCTGTGAGGGTTTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCATCAGGGGCAGCTGATGGAACT
GTGGTTTTGTGGAATGCACAGTCATACAAATTATATAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCGGCATGTGCATTTTCTCCTAAT
GGAAGCTTCTTTGTCACTGGCTCCTCATGTGGTGATTTAACAGTGTGGGATGATAAAATGAGGTGTCCGCATAGTGAAAAAGCACATGAT
CTTGGAATTACCTGCTGCGATTTTTCTTCACAGCCAGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTTCGACTGGCATCATGTGGTCAG
GATTGCCAAGTCAAAATTTGGATTGTTTCTTTTACCCATATCTTAGATGATATCATCAAGTTGAATCGAAAGGAAGGGAAGAAGCAGAAT
TTTCCAAGACTAAATAGAAGACTCCTCCAGCAAAGTGGTGCCCAGCAATTCAGGATGAGAGTGCGATGGGGAATCCAACAGAATTCTGGT
TTTGGTAAGACTAGTCTGAATCGTAGAGGAAGAGTAATGCCTGGAAAGAGACGTCCTAATGGAGTTATCACTGGCCTTGCAGCTAGGAAA
ACGACTGGAATTCGAAAAGGAATTAGTCCTATGAATCGTCCACCTCTAAGTGACAAGAATATAGAACAATATTTTCCAGTGTTAAAAAGG
AAGGCAAACCTTCTGAGACAAAATGAAGGGCAGAGGAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAGCTAAGCAGAAAAAATAACATT
CCAGCTAATTTTACCAGGAGTGGAAATAAATTAAATCATCAGAAAGATACTCGTCAGGCAACTTTTCTTTTCAGAAGAGGCCTGAAGGTG
CAGGCCCAGTTGAATACAGAACAACTGCTAGACGATGTAGTAGCAAAGAGAACTCGTCAATGGCGGACTTCCACCACAAATGGAGGGATT
TTGACTGTATCTATTGACAATCCTGGAGCAGTGCAATGCCCAGTAACTCAGAAACCACGATTAACTCGTACTGCTGTACCTTCATTTTTA
ACAAAGCGGGAGCAAAGTGACGTCAAGAAAGTTCCTAAAGGTGTTCCCCTGCAGTTTGACATAAACAGTGTCGGAAAACAGACAGGGATG
ACGTTGAATGAGCGGTTTGGGATCCTGAAGGAACAAAGAGCCACTCTCACATACAACAAAGGGGGAAGCCGCTTTGTCACCGTGGGATAG

>In-frame_WDSUB1_ENST00000409124_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1530nt
ATGGTGAAACTGATTCACACATTAGCTGATCATGGTGACGATGTCAACTGCTGTGCCTTCTCCTTTTCCCTCTTGGCTACTTGCTCCTTG
GACAAAACAATTCGCCTGTACTCGTTACGTGACTTTACTGAACTGCCACATTCTCCATTGAAGTTTCATACCTATGCTGTCCACTGCTGC
TGTTTCTCCCCTTCAGGACATATTTTGGCATCGTGTTCAACAGATGGTACCACTGTCCTATGGAATACTGAAAATGGACAGATGCTGGCA
GTGATGGAACAGCCTAGTGGCAGCCCTGTGAGGGTTTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCATCAGGGGCAGCTGATGGAACT
GTGGTTTTGTGGAATGCACAGTCATACAAATTATATAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCGGCATGTGCATTTTCTCCTAAT
GGAAGCTTCTTTGTCACTGGCTCCTCATGTGGTGATTTAACAGTGTGGGATGATAAAATGAGGTGTCCGCATAGTGAAAAAGCACATGAT
CTTGGAATTACCTGCTGCGATTTTTCTTCACAGCCAGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTTCGACTGGCATCATGTGGTCAG
GATTGCCAAGTCAAAATTTGGATTGTTTCTTTTACCCATATCTTAGATGATATCATCAAGTTGAATCGAAAGGAAGGGAAGAAGCAGAAT
TTTCCAAGACTAAATAGAAGACTCCTCCAGCAAAGTGGTGCCCAGCAATTCAGGATGAGAGTGCGATGGGGAATCCAACAGAATTCTGGT
TTTGGTAAGACTAGTCTGAATCGTAGAGGAAGAGTAATGCCTGGAAAGAGACGTCCTAATGGAGTTATCACTGGCCTTGCAGCTAGGAAA
ACGACTGGAATTCGAAAAGGAATTAGTCCTATGAATCGTCCACCTCTAAGTGACAAGAATATAGAACAATATTTTCCAGTGTTAAAAAGG
AAGGCAAACCTTCTGAGACAAAATGAAGGGCAGAGGAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAGCTAAGCAGAAAAAATAACATT
CCAGCTAATTTTACCAGGAGTGGAAATAAATTAAATCATCAGAAAGATACTCGTCAGGCAACTTTTCTTTTCAGAAGAGGCCTGAAGGTG
CAGGCCCAGTTGAATACAGAACAACTGCTAGACGATGTAGTAGCAAAGAGAACTCGTCAATGGCGGACTTCCACCACAAATGGAGGGATT
TTGACTGTATCTATTGACAATCCTGGAGCAGTGCAATGCCCAGTAACTCAGAAACCACGATTAACTCGTACTGCTGTACCTTCATTTTTA
ACAAAGCGGGAGCAAAGTGACGTCAAGAAAGTTCCTAAAGGTGTTCCCCTGCAGTTTGACATAAACAGTGTCGGAAAACAGACAGGGATG
ACGTTGAATGAGCGGTTTGGGATCCTGAAGGAACAAAGAGCCACTCTCACATACAACAAAGGGGGAAGCCGCTTTGTCACCGTGGGATAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_WDSUB1_ENST00000359774_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1996nt
GGGGCCTACTCCCTCCGCTCTGGGTCACAGCGGGCGTTCGGGGGGCGGGGCCTGTTCCCTCCGCTCTGGGTCCCCGCGGGCGTTCGGGGG
CGGGGCCTGTTCCCTCTGCTCTGGGTCTCCGCCGGCGCCCGCCCCGCCAGCCTCACCTGCGCGGCACGTGACCCGCACCGCCCGTGGGCA
CCTTGAAGGCGGATCCCGCGCGCCCCCGCTCCTGCAGGCTGTTTTTCTTCAAATAAAGAACATGGTGAAACTGATTCACACATTAGCTGA
TCATGGTGACGATGTCAACTGCTGTGCCTTCTCCTTTTCCCTCTTGGCTACTTGCTCCTTGGACAAAACAATTCGCCTGTACTCGTTACG
TGACTTTACTGAACTGCCACATTCTCCATTGAAGTTTCATACCTATGCTGTCCACTGCTGCTGTTTCTCCCCTTCAGGACATATTTTGGC
ATCGTGTTCAACAGATGGTACCACTGTCCTATGGAATACTGAAAATGGACAGATGCTGGCAGTGATGGAACAGCCTAGTGGCAGCCCTGT
GAGGGTTTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCATCAGGGGCAGCTGATGGAACTGTGGTTTTGTGGAATGCACAGTCATACAA
ATTATATAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCGGCATGTGCATTTTCTCCTAATGGAAGCTTCTTTGTCACTGGCTCCTCATG
TGGTGATTTAACAGTGTGGGATGATAAAATGAGGTGTCCGCATAGTGAAAAAGCACATGATCTTGGAATTACCTGCTGCGATTTTTCTTC
ACAGCCAGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTTCGACTGGCATCATGTGGTCAGGATTGCCAAGTCAAAATTTGGATTGTTTC
TTTTACCCATATCTTAGATGATATCATCAAGTTGAATCGAAAGGAAGGGAAGAAGCAGAATTTTCCAAGACTAAATAGAAGACTCCTCCA
GCAAAGTGGTGCCCAGCAATTCAGGATGAGAGTGCGATGGGGAATCCAACAGAATTCTGGTTTTGGTAAGACTAGTCTGAATCGTAGAGG
AAGAGTAATGCCTGGAAAGAGACGTCCTAATGGAGTTATCACTGGCCTTGCAGCTAGGAAAACGACTGGAATTCGAAAAGGAATTAGTCC
TATGAATCGTCCACCTCTAAGTGACAAGAATATAGAACAATATTTTCCAGTGTTAAAAAGGAAGGCAAACCTTCTGAGACAAAATGAAGG
GCAGAGGAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAGCTAAGCAGAAAAAATAACATTCCAGCTAATTTTACCAGGAGTGGAAATAA
ATTAAATCATCAGAAAGATACTCGTCAGGCAACTTTTCTTTTCAGAAGAGGCCTGAAGGTGCAGGCCCAGTTGAATACAGAACAACTGCT
AGACGATGTAGTAGCAAAGAGAACTCGTCAATGGCGGACTTCCACCACAAATGGAGGGATTTTGACTGTATCTATTGACAATCCTGGAGC
AGTGCAATGCCCAGTAACTCAGAAACCACGATTAACTCGTACTGCTGTACCTTCATTTTTAACAAAGCGGGAGCAAAGTGACGTCAAGAA
AGTTCCTAAAGGTGTTCCCCTGCAGTTTGACATAAACAGTGTCGGAAAACAGACAGGGATGACGTTGAATGAGCGGTTTGGGATCCTGAA
GGAACAAAGAGCCACTCTCACATACAACAAAGGGGGAAGCCGCTTTGTCACCGTGGGATAGGTCCCATGTCAAAGGAACTTTTGAGTGAT
GACTCTGAGAAGTTGAATTGCTTGAAGAGTTCATCACGGAAATTCAAGAAACTTTACTTCAAAATATTCACAAGGCTAAATAACTCTTAT
TTTTATTTTTGAAGGTTTTTTTTTTTAAAAAAAAAAACGTATAAAATAATGCCCTGAAAGAATAATAGGGATTATACCTGTCTGTTCTTA

>In-frame_WDSUB1_ENST00000358147_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1900nt
CTGTTCCCTCTGCTCTGGGTCTCCGCCGGCGCCCGCCCCGCCAGCCTCACCTGCGCGGCACGTGACCCGCACCGCCCGTGGGCACCTTGA
AGGCGGATCCCGCGCGCCCCCGCTCCTGCAGGCTGTTTTTCTTCAAATAAAGAACATGGTGAAACTGATTCACACATTAGCTGATCATGG
TGACGATGTCAACTGCTGTGCCTTCTCCTTTTCCCTCTTGGCTACTTGCTCCTTGGACAAAACAATTCGCCTGTACTCGTTACGTGACTT
TACTGAACTGCCACATTCTCCATTGAAGTTTCATACCTATGCTGTCCACTGCTGCTGTTTCTCCCCTTCAGGACATATTTTGGCATCGTG
TTCAACAGATGGTACCACTGTCCTATGGAATACTGAAAATGGACAGATGCTGGCAGTGATGGAACAGCCTAGTGGCAGCCCTGTGAGGGT
TTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCATCAGGGGCAGCTGATGGAACTGTGGTTTTGTGGAATGCACAGTCATACAAATTATA
TAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCGGCATGTGCATTTTCTCCTAATGGAAGCTTCTTTGTCACTGGCTCCTCATGTGGTGA
TTTAACAGTGTGGGATGATAAAATGAGGTGTCCGCATAGTGAAAAAGCACATGATCTTGGAATTACCTGCTGCGATTTTTCTTCACAGCC
AGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTTCGACTGGCATCATGTGGTCAGGATTGCCAAGTCAAAATTTGGATTGTTTCTTTTAC
CCATATCTTAGATGATATCATCAAGTTGAATCGAAAGGAAGGGAAGAAGCAGAATTTTCCAAGACTAAATAGAAGACTCCTCCAGCAAAG
TGGTGCCCAGCAATTCAGGATGAGAGTGCGATGGGGAATCCAACAGAATTCTGGTTTTGGTAAGACTAGTCTGAATCGTAGAGGAAGAGT
AATGCCTGGAAAGAGACGTCCTAATGGAGTTATCACTGGCCTTGCAGCTAGGAAAACGACTGGAATTCGAAAAGGAATTAGTCCTATGAA
TCGTCCACCTCTAAGTGACAAGAATATAGAACAATATTTTCCAGTGTTAAAAAGGAAGGCAAACCTTCTGAGACAAAATGAAGGGCAGAG
GAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAGCTAAGCAGAAAAAATAACATTCCAGCTAATTTTACCAGGAGTGGAAATAAATTAAA
TCATCAGAAAGATACTCGTCAGGCAACTTTTCTTTTCAGAAGAGGCCTGAAGGTGCAGGCCCAGTTGAATACAGAACAACTGCTAGACGA
TGTAGTAGCAAAGAGAACTCGTCAATGGCGGACTTCCACCACAAATGGAGGGATTTTGACTGTATCTATTGACAATCCTGGAGCAGTGCA
ATGCCCAGTAACTCAGAAACCACGATTAACTCGTACTGCTGTACCTTCATTTTTAACAAAGCGGGAGCAAAGTGACGTCAAGAAAGTTCC
TAAAGGTGTTCCCCTGCAGTTTGACATAAACAGTGTCGGAAAACAGACAGGGATGACGTTGAATGAGCGGTTTGGGATCCTGAAGGAACA
AAGAGCCACTCTCACATACAACAAAGGGGGAAGCCGCTTTGTCACCGTGGGATAGGTCCCATGTCAAAGGAACTTTTGAGTGATGACTCT
GAGAAGTTGAATTGCTTGAAGAGTTCATCACGGAAATTCAAGAAACTTTACTTCAAAATATTCACAAGGCTAAATAACTCTTATTTTTAT
TTTTGAAGGTTTTTTTTTTTAAAAAAAAAAACGTATAAAATAATGCCCTGAAAGAATAATAGGGATTATACCTGTCTGTTCTTAAAGATT

>In-frame_WDSUB1_ENST00000409124_chr2_160132057_-_FYTTD1_ENST00000415708_chr3_197483297_+_1866nt
GCCCCGCCAGCCTCACCTGCGCGGCACGTGACCCGCACCGCCCGTGGGCACCTTGAAGGCGGATCCCGCGCGCCCCCGCTCCTGCAGGCT
GTTTTTCTTCAAATAAAGAACATGGTGAAACTGATTCACACATTAGCTGATCATGGTGACGATGTCAACTGCTGTGCCTTCTCCTTTTCC
CTCTTGGCTACTTGCTCCTTGGACAAAACAATTCGCCTGTACTCGTTACGTGACTTTACTGAACTGCCACATTCTCCATTGAAGTTTCAT
ACCTATGCTGTCCACTGCTGCTGTTTCTCCCCTTCAGGACATATTTTGGCATCGTGTTCAACAGATGGTACCACTGTCCTATGGAATACT
GAAAATGGACAGATGCTGGCAGTGATGGAACAGCCTAGTGGCAGCCCTGTGAGGGTTTGCCAGTTTTCCCCAGACTCCACGTGTTTGGCA
TCAGGGGCAGCTGATGGAACTGTGGTTTTGTGGAATGCACAGTCATACAAATTATATAGATGTGGTAGTGTTAAAGATGGCTCCTTGGCG
GCATGTGCATTTTCTCCTAATGGAAGCTTCTTTGTCACTGGCTCCTCATGTGGTGATTTAACAGTGTGGGATGATAAAATGAGGTGTCCG
CATAGTGAAAAAGCACATGATCTTGGAATTACCTGCTGCGATTTTTCTTCACAGCCAGTTTCTGATGGAGAACAAGGTCTTCAGTTTTTT
CGACTGGCATCATGTGGTCAGGATTGCCAAGTCAAAATTTGGATTGTTTCTTTTACCCATATCTTAGATGATATCATCAAGTTGAATCGA
AAGGAAGGGAAGAAGCAGAATTTTCCAAGACTAAATAGAAGACTCCTCCAGCAAAGTGGTGCCCAGCAATTCAGGATGAGAGTGCGATGG
GGAATCCAACAGAATTCTGGTTTTGGTAAGACTAGTCTGAATCGTAGAGGAAGAGTAATGCCTGGAAAGAGACGTCCTAATGGAGTTATC
ACTGGCCTTGCAGCTAGGAAAACGACTGGAATTCGAAAAGGAATTAGTCCTATGAATCGTCCACCTCTAAGTGACAAGAATATAGAACAA
TATTTTCCAGTGTTAAAAAGGAAGGCAAACCTTCTGAGACAAAATGAAGGGCAGAGGAAACCAGTAGCAGTTCTCAAGAGACCTAGCCAG
CTAAGCAGAAAAAATAACATTCCAGCTAATTTTACCAGGAGTGGAAATAAATTAAATCATCAGAAAGATACTCGTCAGGCAACTTTTCTT
TTCAGAAGAGGCCTGAAGGTGCAGGCCCAGTTGAATACAGAACAACTGCTAGACGATGTAGTAGCAAAGAGAACTCGTCAATGGCGGACT
TCCACCACAAATGGAGGGATTTTGACTGTATCTATTGACAATCCTGGAGCAGTGCAATGCCCAGTAACTCAGAAACCACGATTAACTCGT
ACTGCTGTACCTTCATTTTTAACAAAGCGGGAGCAAAGTGACGTCAAGAAAGTTCCTAAAGGTGTTCCCCTGCAGTTTGACATAAACAGT
GTCGGAAAACAGACAGGGATGACGTTGAATGAGCGGTTTGGGATCCTGAAGGAACAAAGAGCCACTCTCACATACAACAAAGGGGGAAGC
CGCTTTGTCACCGTGGGATAGGTCCCATGTCAAAGGAACTTTTGAGTGATGACTCTGAGAAGTTGAATTGCTTGAAGAGTTCATCACGGA
AATTCAAGAAACTTTACTTCAAAATATTCACAAGGCTAAATAACTCTTATTTTTATTTTTGAAGGTTTTTTTTTTTAAAAAAAAAAACGT


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FusionGenePPI for WDSUB1_FYTTD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
WDSUB1FBXO25FYTTD1SHBG, DDX39B, NXF1, HTATSF1, NCL, SSRP1, FYTTD1, TUBB, SERBP1, STRAP, C1QBP, ANP32E, SET, SUPT16H, EIF4A3, MAGOH, GPRASP2, MOV10, SUZ12, RNF2, HIST1H1A, NOL12, RPL10A, RPL14, RPL6, PALM, PLS1, ERICH5, GNG10, PTPRG, GNAZ, GNA11, GNAQ, GNA13, YES1, SRC, CHTOP, LASP1, UBA6, EEPD1, CYB5A, GNG5, CCNY, CCNYL1, PRRC1, GNG7, PROCR, TRIOBP, THOC5, THOC1, RNASEH2A, C17orf85, THOC2, THOC7, FERMT3, SNW1, SARNP, C11orf57, C12orf75, PNN, NXF2, XRCC4, GLTSCR2, RPL37A, SSSCA1, PMVK, HIST1H1E


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for WDSUB1_FYTTD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for WDSUB1_FYTTD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource