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Fusion gene ID: 41743 |
FusionGeneSummary for WASF2_FGR |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: WASF2_FGR | Fusion gene ID: 41743 | Hgene | Tgene | Gene symbol | WASF2 | FGR | Gene ID | 10163 | 2268 |
| Gene name | WAS protein family member 2 | FGR proto-oncogene, Src family tyrosine kinase | |
| Synonyms | IMD2|SCAR2|WASF4|WAVE2|dJ393P12.2 | SRC2|c-fgr|c-src2|p55-Fgr|p55c-fgr|p58-Fgr|p58c-fgr | |
| Cytomap | 1p36.11 | 1p35.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | wiskott-Aldrich syndrome protein family member 2WASP family Verprolin-homologous protein 2WASP family protein member 2WASP family protein member 4protein WAVE-2putative Wiskott-Aldrich syndrome protein family member 4suppressor of cyclic-AMP recepto | tyrosine-protein kinase FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homologc-fgr protooncogenec-src-2 proto-oncogenefeline Gardner-Rasheed sarcoma viral oncogene homologp55-c-fgr proteinproto-oncogene c-Fgrproto-oncogene tyrosine-prote | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9Y6W5 | P09769 | |
| Ensembl transtripts involved in fusion gene | ENST00000430629, ENST00000536657, | ENST00000374005, ENST00000399173, ENST00000545953, ENST00000374004, ENST00000468038, | |
| Fusion gene scores | * DoF score | 9 X 2 X 11=198 | 4 X 5 X 7=140 |
| # samples | 23 | 11 | |
| ** MAII score | log2(23/198*10)=0.216133430864766 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(11/140*10)=-0.347923303420307 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: WASF2 [Title/Abstract] AND FGR [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FGR | GO:0018108 | peptidyl-tyrosine phosphorylation | 7519620|8327512 |
| Tgene | FGR | GO:0046777 | protein autophosphorylation | 2181286|8327512 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A1FD-01A | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| TCGA | RV | ESCA | TCGA-L5-A891-01A | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| TCGA | RV | LUSC | TCGA-66-2759-01A | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| TCGA | LD | OV | TCGA-13-0893-01B | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| TCGA | LD | OV | TCGA-23-2078-01A | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| TCGA | RV | SKCM | TCGA-ER-A19W-06A | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| TCGA | RV | UCS | TCGA-NA-A4R1-01A | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000430629 | ENST00000374005 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000430629 | ENST00000399173 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000430629 | ENST00000545953 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000430629 | ENST00000374004 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| 5CDS-intron | ENST00000430629 | ENST00000468038 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000536657 | ENST00000374005 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000536657 | ENST00000399173 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000536657 | ENST00000545953 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| In-frame | ENST00000536657 | ENST00000374004 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| 5CDS-intron | ENST00000536657 | ENST00000468038 | WASF2 | chr1 | 27755271 | - | FGR | chr1 | 27939861 | - |
| 5UTR-5UTR | ENST00000430629 | ENST00000374005 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000430629 | ENST00000399173 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000430629 | ENST00000545953 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-intron | ENST00000430629 | ENST00000374004 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000430629 | ENST00000468038 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000536657 | ENST00000374005 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000536657 | ENST00000399173 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000536657 | ENST00000545953 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-intron | ENST00000536657 | ENST00000374004 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
| 5UTR-5UTR | ENST00000536657 | ENST00000468038 | WASF2 | chr1 | 27816497 | - | FGR | chr1 | 27951662 | - |
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FusionProtFeatures for WASF2_FGR |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| WASF2 | FGR |
| Downstream effector molecule involved in thetransmission of signals from tyrosine kinase receptors and smallGTPases to the actin cytoskeleton. Promotes formation of actinfilaments. Part of the WAVE complex that regulates lamellipodiaformation. The WAVE complex regulates actin filamentreorganization via its interaction with the Arp2/3 complex.{ECO:0000269|PubMed:10381382, ECO:0000269|PubMed:16275905}. | Non-receptor tyrosine-protein kinase that transmitssignals from cell surface receptors devoid of kinase activity andcontributes to the regulation of immune responses, includingneutrophil, monocyte, macrophage and mast cell functions,cytoskeleton remodeling in response to extracellular stimuli,phagocytosis, cell adhesion and migration. Promotes mast celldegranulation, release of inflammatory cytokines and IgE-mediatedanaphylaxis. Acts downstream of receptors that bind the Fc regionof immunoglobulins, such as MS4A2/FCER1B, FCGR2A and/or FCGR2B.Acts downstream of ITGB1 and ITGB2, and regulates actincytoskeleton reorganization, cell spreading and adhesion.Depending on the context, activates or inhibits cellularresponses. Functions as negative regulator of ITGB2 signaling,phagocytosis and SYK activity in monocytes. Required for normalITGB1 and ITGB2 signaling, normal cell spreading and adhesion inneutrophils and macrophages. Functions as positive regulator ofcell migration and regulates cytoskeleton reorganization via RAC1activation. Phosphorylates SYK (in vitro) and promotes SYK-dependent activation of AKT1 and MAP kinase signaling.Phosphorylates PLD2 in antigen-stimulated mast cells, leading toPLD2 activation and the production of the signaling moleculeslysophosphatidic acid and diacylglycerol. Promotes activation ofPIK3R1. Phosphorylates FASLG, and thereby regulates itsubiquitination and subsequent internalization. PhosphorylatesABL1. Promotes phosphorylation of CBL, CTTN, PIK3R1, PTK2/FAK1,PTK2B/PYK2 and VAV2. Phosphorylates HCLS1 that has already beenphosphorylated by SYK, but not unphosphorylated HCLS1.{ECO:0000269|PubMed:10739672, ECO:0000269|PubMed:17164290,ECO:0000269|PubMed:1737799, ECO:0000269|PubMed:7519620}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 268_271 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 318_328 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 333_338 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 347_350 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 364_371 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 379_382 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 391_406 | 43 | 499 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 268_271 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 318_328 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 333_338 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 347_350 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 364_371 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 379_382 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 391_406 | 43 | 282 | Compositional bias | Note=Poly-Pro |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000430629 | - | 2 | 9 | 436_453 | 43 | 499 | Domain | WH2 |
| Hgene | >WASF2 | chr1:27755271 | chr1:27939861 | ENST00000536657 | - | 2 | 8 | 436_453 | 43 | 282 | Domain | WH2 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374004 | - | 8 | 11 | 144_241 | 416 | 530 | Domain | SH2 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374004 | - | 8 | 11 | 263_516 | 416 | 530 | Domain | Protein kinase |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374004 | - | 8 | 11 | 77_138 | 416 | 530 | Domain | SH3 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374005 | - | 10 | 13 | 144_241 | 416 | 530 | Domain | SH2 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374005 | - | 10 | 13 | 263_516 | 416 | 530 | Domain | Protein kinase |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374005 | - | 10 | 13 | 77_138 | 416 | 530 | Domain | SH3 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000399173 | - | 10 | 13 | 144_241 | 416 | 530 | Domain | SH2 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000399173 | - | 10 | 13 | 263_516 | 416 | 530 | Domain | Protein kinase |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000399173 | - | 10 | 13 | 77_138 | 416 | 530 | Domain | SH3 |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374004 | - | 8 | 11 | 269_277 | 416 | 530 | Nucleotide binding | ATP |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000374005 | - | 10 | 13 | 269_277 | 416 | 530 | Nucleotide binding | ATP |
| Tgene | FGR | chr1:27755271 | chr1:27939861 | ENST00000399173 | - | 10 | 13 | 269_277 | 416 | 530 | Nucleotide binding | ATP |
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FusionGeneSequence for WASF2_FGR |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_157aa MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_471nt ATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAAC ATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGC AGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAATCCCCTACCCAGGCATGAAT AAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAG ACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCACCTCCGCTGAACCACAGTAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_1537nt GGGGAATCGCGTAATGGCGGACACAGGCAGGGCGAGCGCGGCTGGGGGCGTAGCGCGCTGAGGGGGTCCGGCCGTTTGGCAGCCCGCGAG GCGGTCCGCGGGAGCACACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTT TTCACCATTCAGAACATTGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTG CCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCC ATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTC ATCACCAAGGGCCGAATCCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCA GGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTC CTGGAGGACTACTTCACCTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGC CACCAGTCCTTGCCAATCCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTG GCTGCTCTGACACCACCTAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCA AGCACTATTTCTTCCTTTTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAG TTATTTATAAAACTGTATGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAG AATTTCCCTTCTACCCTCTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGC AGTGGTCCAGGACTGGGGTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTT TATTGATTCTGTAAATAAGTAAAATGACAATATGAATCCTCAAACCATGAAATACCCTTGAACCTTCCTTTGGGAGCGGGGGTGGTCAAT AGGGGGTGAACGGACAGATATGGCTACAGGCAGCAGCAGGGGAAGCTGGAGAGGGCCCTAATGCCTACCAAGCACGGGGCATCCAAGGTG TGGAGTTTTAGAACACCCAGAGTCCCACTGCTCATCTGCACGTGAGTTTAGAAGACAAGCAGCTGAAGATACATTAAAATGTCCCCTTCG >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_1309nt GGGGAATCGCGTAATGGCGGACACAGGCAGGGCGAGCGCGGCTGGGGGCGTAGCGCGCTGAGGGGGTCCGGCCGTTTGGCAGCCCGCGAG GCGGTCCGCGGGAGCACACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTT TTCACCATTCAGAACATTGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTG CCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCC ATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTC ATCACCAAGGGCCGAATCCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCA GGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTC CTGGAGGACTACTTCACCTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGC CACCAGTCCTTGCCAATCCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTG GCTGCTCTGACACCACCTAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCA AGCACTATTTCTTCCTTTTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAG TTATTTATAAAACTGTATGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAG AATTTCCCTTCTACCCTCTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGC AGTGGTCCAGGACTGGGGTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTT >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_1309nt GGGGAATCGCGTAATGGCGGACACAGGCAGGGCGAGCGCGGCTGGGGGCGTAGCGCGCTGAGGGGGTCCGGCCGTTTGGCAGCCCGCGAG GCGGTCCGCGGGAGCACACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTT TTCACCATTCAGAACATTGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTG CCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCC ATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTC ATCACCAAGGGCCGAATCCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCA GGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTC CTGGAGGACTACTTCACCTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGC CACCAGTCCTTGCCAATCCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTG GCTGCTCTGACACCACCTAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCA AGCACTATTTCTTCCTTTTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAG TTATTTATAAAACTGTATGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAG AATTTCCCTTCTACCCTCTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGC AGTGGTCCAGGACTGGGGTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTT >In-frame_WASF2_ENST00000430629_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_1301nt GGGGAATCGCGTAATGGCGGACACAGGCAGGGCGAGCGCGGCTGGGGGCGTAGCGCGCTGAGGGGGTCCGGCCGTTTGGCAGCCCGCGAG GCGGTCCGCGGGAGCACACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTT TTCACCATTCAGAACATTGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTG CCTAGCGTTAGAAGCGAGCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCC ATCAAGTGGACAGCCCCAGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTC ATCACCAAGGGCCGAATCCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCA GGCTGCCCAGCATCCCTGTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTC CTGGAGGACTACTTCACCTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGC CACCAGTCCTTGCCAATCCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTG GCTGCTCTGACACCACCTAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCA AGCACTATTTCTTCCTTTTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAG TTATTTATAAAACTGTATGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAG AATTTCCCTTCTACCCTCTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGC AGTGGTCCAGGACTGGGGTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTT >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374005_chr1_27939861_-_1430nt ACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTTTTCACCATTCAGAACAT TGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGA GCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCC AGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAAT CCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCT GTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCAC CTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGCCACCAGTCCTTGCCAAT CCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTGGCTGCTCTGACACCACC TAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCAAGCACTATTTCTTCCTT TTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAGTTATTTATAAAACTGTA TGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAGAATTTCCCTTCTACCCT CTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGCAGTGGTCCAGGACTGGG GTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTTTATTGATTCTGTAAATA AGTAAAATGACAATATGAATCCTCAAACCATGAAATACCCTTGAACCTTCCTTTGGGAGCGGGGGTGGTCAATAGGGGGTGAACGGACAG ATATGGCTACAGGCAGCAGCAGGGGAAGCTGGAGAGGGCCCTAATGCCTACCAAGCACGGGGCATCCAAGGTGTGGAGTTTTAGAACACC >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000399173_chr1_27939861_-_1202nt ACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTTTTCACCATTCAGAACAT TGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGA GCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCC AGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAAT CCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCT GTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCAC CTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGCCACCAGTCCTTGCCAAT CCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTGGCTGCTCTGACACCACC TAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCAAGCACTATTTCTTCCTT TTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAGTTATTTATAAAACTGTA TGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAGAATTTCCCTTCTACCCT CTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGCAGTGGTCCAGGACTGGG GTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTTTATTGATTCTGTAAATA >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000545953_chr1_27939861_-_1202nt ACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTTTTCACCATTCAGAACAT TGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGA GCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCC AGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAAT CCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCT GTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCAC CTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGCCACCAGTCCTTGCCAAT CCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTGGCTGCTCTGACACCACC TAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCAAGCACTATTTCTTCCTT TTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAGTTATTTATAAAACTGTA TGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAGAATTTCCCTTCTACCCT CTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGCAGTGGTCCAGGACTGGG GTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTTTATTGATTCTGTAAATA >In-frame_WASF2_ENST00000536657_chr1_27755271_-_FGR_ENST00000374004_chr1_27939861_-_1194nt ACTCTGTGCGGAGACTGGGCGGCCGGCCGACCCTTCCTGTCGCTGACGGCGACTGCGGGAGGCCAGGTTGTTTTTCACCATTCAGAACAT TGCCTGAAGCAGGTCCACCATGCCGTTAGTAACGAGGAACATCGAGCCAAGGCACCTGTGCCGTCAGACGTTGCCTAGCGTTAGAAGCGA GCTGGAATGCGTGACCAACATCACCCTGGCAAATGTCATCCGACAGCTGGGCAGCCTGAGTTCCAAGTTCCCCATCAAGTGGACAGCCCC AGAAGCTGCCCTCTTTGGCAGATTCACCATCAAGTCAGACGTGTGGTCCTTTGGGATCCTGCTCACTGAGCTCATCACCAAGGGCCGAAT CCCCTACCCAGGCATGAATAAACGGGAAGTGTTGGAACAGGTGGAGCAGGGCTACCACATGCCGTGCCCTCCAGGCTGCCCAGCATCCCT GTACGAGGCCATGGAACAGACCTGGCGTCTGGACCCGGAGGAGAGGCCTACCTTCGAGTACCTGCAGTCCTTCCTGGAGGACTACTTCAC CTCCGCTGAACCACAGTACCAGCCCGGGGATCAGACATAGCCTGTCCGGGCATCAACCCTCTCTGGCGGTGGCCACCAGTCCTTGCCAAT CCCCAGAGCTGTTCTTCCAAAGCCCCCAGGCTGGCTTAGAACCCCATAGAGTCCTAGCATCACCGAGGACGTGGCTGCTCTGACACCACC TAGGGCAACCTACTTGTTTTACAGATGGGGCAAAAGGAGGCCCAGAGCTGATCTCTCATCCGCTCTGGCCCCAAGCACTATTTCTTCCTT TTCCACTTAGGCCCCTACATGCCTGTAGCCTTTCTCACTCCATCCCCACCCAAAGTGCTCAGACCTTGTCTAGTTATTTATAAAACTGTA TGTACCTCCCTCACTTCTCTCCTATCACTGCTTTCCTACTCTCCTTTTATCTCACTCTAGTCCAGGTGCCAAGAATTTCCCTTCTACCCT CTATTCTCTTGTGTCTGTAAGTTACAAAGTCAGGAAAAGTCTTGGCTGGACCCCTTTCCTGCTGGGTGGATGCAGTGGTCCAGGACTGGG GTCTGGGCCCAGGTTTGAGGGAGAAGGTTGCAGAGCACTTCCCACCTCTCTGAATAGTGTGTATGTGTTGGTTTATTGATTCTGTAAATA |
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FusionGenePPI for WASF2_FGR |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| WASF2 | ACTR3, BAIAP2, RYK, ITSN2, WASL, KLF16, YWHAQ, TCERG1, PRPF40A, APBB1, GAS7, POLD1, ZDHHC17, ABI3, ABI1, ABI2, ZNF511, NCK2, LHX4, CYFIP1, CYFIP2, NCKAP1, NTRK1, CEP19, TMEM17, TCF4, CDH1, TIMM50, NHSL2, AMZ1, CCDC53, CBLC, GJB7, HOMER3, CCDC27, EVL, TRIM25 | FGR | WAS, DOK1, CCR3, HCLS1, PTK2, SLAMF1, CBL, SYK, CD24, DAB2, FASLG, IKBKG, KHDRBS1, SH3KBP1, HSP90AA1, ERBB2, STAT3, NR1I2, EGFR, CDK18, CDK9, SMURF1, YES1, CDK14 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for WASF2_FGR |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | FGR | P09769 | DB01254 | Dasatinib | Tyrosine-protein kinase Fgr | small molecule | approved|investigational |
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RelatedDiseases for WASF2_FGR |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | FGR | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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