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Fusion gene ID: 41557 |
FusionGeneSummary for VPS13D_VEGFC |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS13D_VEGFC | Fusion gene ID: 41557 | Hgene | Tgene | Gene symbol | VPS13D | VEGFC | Gene ID | 55187 | 7424 |
| Gene name | vacuolar protein sorting 13 homolog D | vascular endothelial growth factor C | |
| Synonyms | - | Flt4-L|LMPH1D|VRP | |
| Cytomap | 1p36.22-p36.21 | 4q34.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 13Dvacuolar protein sorting 13D | vascular endothelial growth factor CFLT4 ligand DHMvascular endothelial growth factor-related protein | |
| Modification date | 20180525 | 20180527 | |
| UniProtAcc | Q5THJ4 | P49767 | |
| Ensembl transtripts involved in fusion gene | ENST00000358136, ENST00000356315, ENST00000496628, ENST00000543766, ENST00000471923, ENST00000543710, | ENST00000280193, ENST00000507638, | |
| Fusion gene scores | * DoF score | 6 X 6 X 5=180 | 3 X 2 X 3=18 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: VPS13D [Title/Abstract] AND VEGFC [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | VEGFC | GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 23878260 |
| Tgene | VEGFC | GO:0050930 | induction of positive chemotaxis | 19275959 |
| Tgene | VEGFC | GO:0060754 | positive regulation of mast cell chemotaxis | 19275959 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | CHOL | TCGA-W5-AA2Z-01A | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000358136 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| 5CDS-intron | ENST00000358136 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| In-frame | ENST00000356315 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| 5CDS-intron | ENST00000356315 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-3CDS | ENST00000496628 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-intron | ENST00000496628 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-3CDS | ENST00000543766 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-intron | ENST00000543766 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-3CDS | ENST00000471923 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-intron | ENST00000471923 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-3CDS | ENST00000543710 | ENST00000280193 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
| intron-intron | ENST00000543710 | ENST00000507638 | VPS13D | chr1 | 12353761 | + | VEGFC | chr4 | 177650900 | - |
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FusionProtFeatures for VPS13D_VEGFC |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS13D | VEGFC |
| Growth factor active in angiogenesis, and endothelialcell growth, stimulating their proliferation and migration andalso has effects on the permeability of blood vessels. Mayfunction in angiogenesis of the venous and lymphatic vascularsystems during embryogenesis, and also in the maintenance ofdifferentiated lymphatic endothelium in adults. Binds andactivates KDR/VEGFR2 and FLT4/VEGFR3 receptors.{ECO:0000269|PubMed:20145116}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >VEGFC | chr1:12353761 | chr4:177650900 | ENST00000280193 | - | 0 | 7 | 280_362 | 49 | 421 | Region | Note=4 X 16 AA repeats of C-X(10)-C-X-C-X(1%2C3)-C |
| Tgene | >VEGFC | chr1:12353761 | chr4:177650900 | ENST00000280193 | - | 0 | 7 | 280_295 | 49 | 421 | Repeat | Note=1 |
| Tgene | >VEGFC | chr1:12353761 | chr4:177650900 | ENST00000280193 | - | 0 | 7 | 304_319 | 49 | 421 | Repeat | Note=2 |
| Tgene | >VEGFC | chr1:12353761 | chr4:177650900 | ENST00000280193 | - | 0 | 7 | 328_343 | 49 | 421 | Repeat | Note=3 |
| Tgene | >VEGFC | chr1:12353761 | chr4:177650900 | ENST00000280193 | - | 0 | 7 | 347_362 | 49 | 421 | Repeat | Note=4 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >VPS13D | chr1:12353761 | chr4:177650900 | ENST00000356315 | + | 24 | 69 | 2633_2676 | 2011 | 4364 | Domain | UBA |
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FusionGeneSequence for VPS13D_VEGFC |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VPS13D_ENST00000358136_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_2383aa MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIK FAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKP VTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDE ETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHH >In-frame_VPS13D_ENST00000356315_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_2383aa MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGFIGKVTLQIPFYRPHVDPWVISISSLHLIGA PEKIQDFNDEKEKLLERERKKALLQALEEKWKNDRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVS MQNAVNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQ LETIPLKLSQLQYRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFMLHRARDAVSYTDKYFNKL KGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELAESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPE GNVVEGLSAEQQEQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNESAFMQLEFSDVKLLAESL PRRNSSLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVST RPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMS TKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFAL LTTPEMKTSDTQIKEKIFPQEEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKR PYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLI KLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEI HRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVR MEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTR EPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLA GREAVGSEGSRMFCPPSGSGSANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGTSSIMKIEGKFV NPVQVVLAKHVYEQVLQTLDNLVYSEDLNKYPASATSSPCPDSPLPPLSTCGESSVERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSC PSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVHINIFLVDKKHPEFS SSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSLSLVLNKTT SELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDIRVSLRMASVQYVHTQ RFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIK FAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKP VTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDE ETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VPS13D_ENST00000358136_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_7149nt ATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATATGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTT CTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTTGAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTC ATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCCTTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCC CCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAGGGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAA TGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTACCGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTA AAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTCCCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCC ATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCAATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGAT TGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGCCAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAG CCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCTGCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAG CTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCATGGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTG AAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGAATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATC AGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCGTGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTA AAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGAAGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAA CTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCGGGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCC CCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTTTCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAA GGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCCTGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACT GCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGCCAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTG TTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCAGCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTT CCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCTTCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTA GTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGGTCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCA GCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCCGGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACA AGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGACTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGT TATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATATAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAA ACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATGGACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTT CCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGGAAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGG AAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGAATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCT CCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGTTGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGC ACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCATGGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGAT ATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACAGTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATAT CCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAATGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTC CTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGATTTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCC GTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGAGGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAA GTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGTGCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGG CCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGATACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATG GCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGATAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCC CACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTCACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATT AAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGACAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTA GATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCAAAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAA CCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCAGTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATC CATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGAGAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGC ACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCTTGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTT AAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATATCATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGA ATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAGATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCT TTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCATGGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGC GCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAGCGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGG GAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTCGTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAAC ATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTTGTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTT GTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAAGGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCA GGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTCCGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTC ACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACATCCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATC CCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCTGGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTC AATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACAAACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAG TATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCCCCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAG AATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATTGTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCC ACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTTGGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTT GAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGCCCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAAT CCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCCATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGC CCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTCCCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAA AGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGACTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAG CCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACATCAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCT TCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTTGGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTA GACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCCTCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACAT GCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCTCAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACC AGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAATGATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGT CTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTTCACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTT AAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGTGAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAG CGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCAGGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAG ACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAGTGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGG AAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGCAACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAA TTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGAGTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATA GATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCTTCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGGGGTTGCTGCAATAGT GAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACGTTATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCA GTAACAATCAGTTTTGCCAATCACACTTCCTGCCGATGCATGTCTAAACTGGATGTTTACAGACAAGTTCATTCCATTATTAGACGTTCC CTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCCACCAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCT CAGGAAGATTTTATGTTTTCCTCGGATGCTGGAGATGACTCAACAGATGGATTCCATGACATCTGTGGACCAAACAAGGAGCTGGATGAA GAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGTGGACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTC TGTAAAAACAAACTCTTCCCCAGCCAATGTGGGGCCAACCGAGAATTTGATGAAAACACATGCCAGTGTGTATGTAAAAGAACCTGCCCC AGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAAAGTCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCAC CAAACATGCAGCTGTTACAGACGGCCATGTACGAACCGCCAGAAGGCTTGTGAGCCAGGATTTTCATATAGTGAAGAAGTGTGTCGTTGT >In-frame_VPS13D_ENST00000356315_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_7149nt ATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATATGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTT CTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTTGAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTC ATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCCTTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCC CCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAGGGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAA TGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTACCGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTA AAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTCCCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCC ATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCAATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGAT TGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGCCAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAG CCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCTGCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAG CTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCATGGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTG AAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGAATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATC AGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCGTGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTA AAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGAAGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAA CTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCGGGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCC CCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTTTCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAA GGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCCTGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACT GCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGCCAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTG TTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCAGCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTT CCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCTTCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTA GTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGGTCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCA GCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCCGGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACA AGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGACTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGT TATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATATAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAA ACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATGGACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTT CCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGGAAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGG AAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGAATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCT CCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGTTGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGC ACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCATGGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGAT ATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACAGTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATAT CCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAATGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTC CTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGATTTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCC GTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGAGGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAA GTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGTGCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGG CCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGATACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATG GCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGATAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCC CACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTCACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATT AAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGACAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTA GATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCAAAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAA CCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCAGTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATC CATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGAGAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGC ACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCTTGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTT AAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATATCATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGA ATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAGATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCT TTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCATGGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGC GCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAGCGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGG GAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTCGTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAAC ATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTTGTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTT GTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAAGGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCA GGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTCCGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTC ACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACATCCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATC CCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCTGGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTC AATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACAAACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAG TATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCCCCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAG AATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATTGTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCC ACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTTGGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTT GAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGCCCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAAT CCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCCATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGC CCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTCCCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAA AGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGACTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAG CCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACATCAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCT TCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTTGGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTA GACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCCTCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACAT GCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCTCAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACC AGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAATGATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGT CTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTTCACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTT AAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGTGAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAG CGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCAGGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAG ACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAGTGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGG AAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGCAACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAA TTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGAGTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATA GATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCTTCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGGGGTTGCTGCAATAGT GAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACGTTATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCA GTAACAATCAGTTTTGCCAATCACACTTCCTGCCGATGCATGTCTAAACTGGATGTTTACAGACAAGTTCATTCCATTATTAGACGTTCC CTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCCACCAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCT CAGGAAGATTTTATGTTTTCCTCGGATGCTGGAGATGACTCAACAGATGGATTCCATGACATCTGTGGACCAAACAAGGAGCTGGATGAA GAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGTGGACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTC TGTAAAAACAAACTCTTCCCCAGCCAATGTGGGGCCAACCGAGAATTTGATGAAAACACATGCCAGTGTGTATGTAAAAGAACCTGCCCC AGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAAAGTCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCAC CAAACATGCAGCTGTTACAGACGGCCATGTACGAACCGCCAGAAGGCTTGTGAGCCAGGATTTTCATATAGTGAAGAAGTGTGTCGTTGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VPS13D_ENST00000358136_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_7667nt GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAG TGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGCAACATAACAGAGA ACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAATTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGA GTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCTTCTTTAAACCTCC ATGTGTGTCCGTCTACAGATGTGGGGGTTGCTGCAATAGTGAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACGTT ATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCAGTAACAATCAGTTTTGCCAATCACACTTCCTGCCGATGCATGTCTAAACT GGATGTTTACAGACAAGTTCATTCCATTATTAGACGTTCCCTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCCAC CAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCTCAGGAAGATTTTATGTTTTCCTCGGATGCTGGAGATGACTCAACAGATGG ATTCCATGACATCTGTGGACCAAACAAGGAGCTGGATGAAGAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGTGG ACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTCTGTAAAAACAAACTCTTCCCCAGCCAATGTGGGGCCAACCGAGAATTTGA TGAAAACACATGCCAGTGTGTATGTAAAAGAACCTGCCCCAGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAAAG TCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCACCAAACATGCAGCTGTTACAGACGGCCATGTACGAACCGCCAGAAGGCTTG TGAGCCAGGATTTTCATATAGTGAAGAAGTGTGTCGTTGTGTCCCTTCATATTGGAAAAGACCACAAATGATGAGCTAAGATTGTACTGT TTTCCAGTTCATCGATTTTCTATTATGGAAAACTGTGTTGCCACAGTAGAACTGTCTGTGAACAGAGAGACCCTTGTGGGTCCATGCTAA CAAAGACAAAAGTCTGTCTTTCCTGAACCATGTGGATAACTTTACAGAAATGGACTGGAGCTCATCTGCAAAAGGCCTCTTGTAAAGACT GGTTTTCTGCCAATGACCAAACAGCCAAGATTTTCCTCTTGTGATTTCTTTAAAAGAATGACTATATAATTTATTTCCACTAAAAATATT GTTTCTGCATTCATTTTTATAGCAACAACAATTGGTAAAACTCACTGTGATCAATATTTTTATATCATGCAAAATATGTTTAAAATAAAA >In-frame_VPS13D_ENST00000356315_chr1_12353761_+_VEGFC_ENST00000280193_chr4_177650900_-_7667nt GGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAAT GATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATA TGTCAATAACCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTT GAAAGAATTGGAATTACCATTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCC TTGGGTGATCTCCATCTCCAGCCTTCACTTAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAG GGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAAATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTAC CGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAAGATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTC CCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATGAGCCTGTACAGAAACTAATGCGGAAAAAGCA ATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGATGGAGTTACAGGAGGCCATGGC CAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCCAAGAAGCCCCT GCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCAT GGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGA ATGGTGGTATTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCG TGATGCTGTATCTTACACTGACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGA AGAGGAACAGAGCTTTGAGGAATTGAAGATTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCG GGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGCCCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTT TCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTGGTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCC TGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGAACACGTATACAAAGCGAGATCATGTCTTTGC CAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAATGAATGAAAGTGCTTTCATGCA GCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGTGGACTGTTTCT TCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTGG TCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCC GGCGCACAGCCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGA CTTTTTCTACAAGGGAAAGGTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATA TAACAAGCTGAAGATGCAGACCAAGGCAGAAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATG GACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATTTCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGG AAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGGGATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGA ATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCAACGGAGAGAAAACACCTCCCTTTTCTGGAGT TGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTCATTTATGGACCTCCAGATCAT GGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAACGTTCACCTACA GTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTAA TGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGAT TTTTCCCCAGGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGA GGTTCTGGTGGAGTCGCAGCTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGT GCTCAAGGTGTTTGGTACCAATGCTCACTTTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGA TACCATGCAGACATATGGTGCTGATTTTGACCTTTTGATGGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGA TAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACTGATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTC ACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTGTGAGTTCAGAGTGCCCATCGATGAATTTAGA CAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGTGGAGCTAATTGGTTTTCTTCA AAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAAGGAACTTACCA GTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAGA GAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCT TGGCTGTTTACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATAT CATCAGTGATATTGGCTACTTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAG ATCTAAACAGGAGTGTTTTCTCAACCTGAAGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCAT GGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAGCGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAG CGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTTATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTC GTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTTCTATCCCTCGGAAGCCGGGGAGTCCTGAGTT GTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGACCGTCTGCAGGTGGAAATCAA GGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTTTGCCCACCTTC CGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACAT CCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCT GGGAACTTCTAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACA AACCCTGGACAATCTCGTGTACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCC CCTCAGTACCTGTGGAGAATCTTCTGTTGAAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATT GTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGCCACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTT GGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAATTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGC CCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGAACCTGATGGTGTCTCGAGGAGCCCCTAAGCC ATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGATATGCCTCGGTCTCTCCCTTC CCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTCCAAGACAAGGA CTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACAT CAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTT GGATGTGCTGATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCC TCCTGAGGGCATTCTGCACAACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCT CAAGGTTCATTCACTTTCTCTAGTGCTGAATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAAT GATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAGTCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTT CACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGACGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGT GAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGGTGGCCTTCATTCAGCATTTCACTCAGCTGCA GGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAG TGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGCAACATAACAGAGA ACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAATTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGA GTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCTTCTTTAAACCTCC ATGTGTGTCCGTCTACAGATGTGGGGGTTGCTGCAATAGTGAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACGTT ATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCAGTAACAATCAGTTTTGCCAATCACACTTCCTGCCGATGCATGTCTAAACT GGATGTTTACAGACAAGTTCATTCCATTATTAGACGTTCCCTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCCAC CAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCTCAGGAAGATTTTATGTTTTCCTCGGATGCTGGAGATGACTCAACAGATGG ATTCCATGACATCTGTGGACCAAACAAGGAGCTGGATGAAGAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGTGG ACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTCTGTAAAAACAAACTCTTCCCCAGCCAATGTGGGGCCAACCGAGAATTTGA TGAAAACACATGCCAGTGTGTATGTAAAAGAACCTGCCCCAGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAAAG TCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCACCAAACATGCAGCTGTTACAGACGGCCATGTACGAACCGCCAGAAGGCTTG TGAGCCAGGATTTTCATATAGTGAAGAAGTGTGTCGTTGTGTCCCTTCATATTGGAAAAGACCACAAATGATGAGCTAAGATTGTACTGT TTTCCAGTTCATCGATTTTCTATTATGGAAAACTGTGTTGCCACAGTAGAACTGTCTGTGAACAGAGAGACCCTTGTGGGTCCATGCTAA CAAAGACAAAAGTCTGTCTTTCCTGAACCATGTGGATAACTTTACAGAAATGGACTGGAGCTCATCTGCAAAAGGCCTCTTGTAAAGACT GGTTTTCTGCCAATGACCAAACAGCCAAGATTTTCCTCTTGTGATTTCTTTAAAAGAATGACTATATAATTTATTTCCACTAAAAATATT GTTTCTGCATTCATTTTTATAGCAACAACAATTGGTAAAACTCACTGTGATCAATATTTTTATATCATGCAAAATATGTTTAAAATAAAA |
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FusionGenePPI for VPS13D_VEGFC |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VPS13D | MADD, ESR1, PPP2R1A, PSMC1 | VEGFC | FLT4, VEGFC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VPS13D_VEGFC |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS13D_VEGFC |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | VPS13D | C0043094 | Weight Gain | 1 | CTD_human |
| Tgene | VEGFC | C1458155 | Mammary Neoplasms | 2 | CTD_human |
| Tgene | VEGFC | C0018923 | Hemangiosarcoma | 1 | CTD_human |
| Tgene | VEGFC | C0025202 | melanoma | 1 | CTD_human |
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