|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 41312 |
FusionGeneSummary for UVRAG_ZMAT4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UVRAG_ZMAT4 | Fusion gene ID: 41312 | Hgene | Tgene | Gene symbol | UVRAG | ZMAT4 | Gene ID | 7405 | 79698 |
| Gene name | UV radiation resistance associated | zinc finger matrin-type 4 | |
| Synonyms | DHTX|VPS38|p63 | - | |
| Cytomap | 11q13.5 | 8p11.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UV radiation resistance-associated gene proteinbeclin 1 binding proteindisrupted in heterotaxy | zinc finger matrin-type protein 4 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9P2Y5 | Q9H898 | |
| Ensembl transtripts involved in fusion gene | ENST00000356136, ENST00000528420, ENST00000533454, ENST00000531818, ENST00000532130, ENST00000539288, ENST00000525872, ENST00000538870, | ENST00000315769, ENST00000297737, ENST00000523823, | |
| Fusion gene scores | * DoF score | 29 X 10 X 12=3480 | 11 X 7 X 7=539 |
| # samples | 29 | 12 | |
| ** MAII score | log2(29/3480*10)=-3.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/539*10)=-2.16725086714399 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UVRAG [Title/Abstract] AND ZMAT4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UVRAG | GO:0071900 | regulation of protein serine/threonine kinase activity | 22542840 |
| Hgene | UVRAG | GO:0097680 | double-strand break repair via classical nonhomologous end joining | 22542840 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A2-A0ES-01A | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000356136 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000356136 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000356136 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| In-frame | ENST00000528420 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000528420 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000528420 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| In-frame | ENST00000533454 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000533454 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000533454 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| In-frame | ENST00000531818 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000531818 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000531818 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| In-frame | ENST00000532130 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000532130 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000532130 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| In-frame | ENST00000539288 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| Frame-shift | ENST00000539288 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| 5CDS-intron | ENST00000539288 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-3CDS | ENST00000525872 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-3CDS | ENST00000525872 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-intron | ENST00000525872 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-3CDS | ENST00000538870 | ENST00000315769 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-3CDS | ENST00000538870 | ENST00000297737 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
| intron-intron | ENST00000538870 | ENST00000523823 | UVRAG | chr11 | 75728024 | + | ZMAT4 | chr8 | 40389757 | - |
Top |
FusionProtFeatures for UVRAG_ZMAT4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UVRAG | ZMAT4 |
| Versatile protein that is involved in regulation ofdifferent cellular pathways implicated in membrane trafficking.Involved in regulation of the COPI-dependent retrograde transportfrom Golgi and the endoplasmic reticulum by associating with theNRZ complex; the function is dependent on its binding tophosphatidylinositol 3-phosphate (PtdIns(3)P) (PubMed:24056303).During autophagy acts as regulatory subunit of the alternativePI3K complex II (PI3KC3-C2) that mediates formation ofphosphatidylinositol 3-phosphate and is believed to be involved inmaturation of autophagosomes and endocytosis. Activates lipidkinase activity of PIK3C3. Involved in the regulation ofdegradative endocytic trafficking and cytokinesis, and inregulation of ATG9A transport from the Golgi to the autophagosome;the functions seems to implicate its association with PI3KC3-C2(PubMed:16799551, PubMed:20643123, PubMed:24056303). Involved inmaturation of autophagosomes and degradative endocytic traffickingindependently of BECN1 but depending on its association with aclass C Vps complex (possibly the HOPS complex); the associationis also proposed to promote autophagosome recruitment andactivation of Rab7 and endosome-endosome fusion events(PubMed:18552835). Enhances class C Vps complex (possibly HOPScomplex) association with a SNARE complex and promotes fusogenicSNARE complex formation during late endocytic membrane fusion(PubMed:24550300). In case of negative-strand RNA virus infectionis required for efficient virus entry, promotes endocytictransport of virions and is implicated in a VAMP8-specificfusogenic SNARE complex assembly (PubMed:24550300).{ECO:0000269|PubMed:18552835, ECO:0000269|PubMed:20643123,ECO:0000269|PubMed:24056303, ECO:0000305}. Involved in maintaining chromosomal stability. PromotesDNA double-strand break (DSB) repair by association with DNA-dependent protein kinase complex DNA-PK and activating it in non-homologous end joining (NHEJ) (PubMed:22542840). Required forcentrosome stability and proper chromosome segregation(PubMed:22542840). {ECO:0000269|PubMed:22542840}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | UVRAG | chr11:75728024 | chr8:40389757 | ENST00000356136 | + | 12 | 15 | 224_305 | 408 | 700 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | UVRAG | chr11:75728024 | chr8:40389757 | ENST00000356136 | + | 12 | 15 | 44_128 | 408 | 700 | Domain | Note=C2 |
| Tgene | >ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000315769 | - | 4 | 6 | 145_175 | 148 | 154 | Zinc finger | Note=Matrin-type 3 |
| Tgene | >ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000315769 | - | 4 | 6 | 198_228 | 148 | 154 | Zinc finger | Note=Matrin-type 4 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000297737 | - | 5 | 7 | 145_175 | 224 | 230 | Zinc finger | Note=Matrin-type 3 |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000297737 | - | 5 | 7 | 14_44 | 224 | 230 | Zinc finger | Note=Matrin-type 1 |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000297737 | - | 5 | 7 | 198_228 | 224 | 230 | Zinc finger | Note=Matrin-type 4 |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000297737 | - | 5 | 7 | 72_106 | 224 | 230 | Zinc finger | Note=Matrin-type 2 |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000315769 | - | 4 | 6 | 14_44 | 148 | 154 | Zinc finger | Note=Matrin-type 1 |
| Tgene | ZMAT4 | chr11:75728024 | chr8:40389757 | ENST00000315769 | - | 4 | 6 | 72_106 | 148 | 154 | Zinc finger | Note=Matrin-type 2 |
Top |
FusionGeneSequence for UVRAG_ZMAT4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UVRAG_ENST00000356136_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_414aa MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSL NPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILL QVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQI ALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSI >In-frame_UVRAG_ENST00000528420_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_313aa MPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSY DVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSA EHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLV >In-frame_UVRAG_ENST00000533454_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_42aa >In-frame_UVRAG_ENST00000531818_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_42aa >In-frame_UVRAG_ENST00000532130_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_42aa >In-frame_UVRAG_ENST00000539288_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_42aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UVRAG_ENST00000356136_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_1242nt ATGAGCGCCTCCGCGTCGGTCGGGGGCCCCGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCC CTGCATGTGGAGCTGCCGTCTCAGCAGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAG CTCCTTGATACCTACTTTACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTG AATCCCACGTGGCGAAGTCTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGA AAGGAGAACATCTACCAGCTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAA AATGAAATAATTTTTGGGCTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTG CAGGTGGATCAGAACTGTGTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAG GTAACTGTTCAGAAAATTGGAAAGGAAATTGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTG CAGTTAAAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATT GCATTACAAGACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGC ACTGCAAAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCT ATTGATTTGAATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATT GCTGTTGCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGG >In-frame_UVRAG_ENST00000528420_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_939nt ATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGAATGG AAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGGATAC TATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTCTTAC GATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATTGGAAAGGAAATTGAA GAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTGCAGTTAAAAATTTTGGTGCTTCAGAATGAACTG GAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTTCAGCT GAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTCTTCTTGAAGACTAAT GCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACTTTGTA TGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTATACTGCACATCTGGTC TCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGAC >In-frame_UVRAG_ENST00000533454_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_126nt ATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGACAAA >In-frame_UVRAG_ENST00000531818_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_126nt ATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGACAAA >In-frame_UVRAG_ENST00000532130_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_126nt ATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGACAAA >In-frame_UVRAG_ENST00000539288_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_126nt ATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGACAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UVRAG_ENST00000356136_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_3116nt AATGAGCGCTCCGGGTCTCAGCGGGGTGGAGGGGTTGCACTGCGGTAATATGGCTCTTCCTTAGCCAGCGGCGGCAACGGCGGCAGCGGC GGCAGCGGCGGCGGCTACTGTCTGGGCTGAGCAGTAGTGCCTCTCGGGTGGCGGGTTTCTAGGCTGCAGGGGCTTGGTAGGTGGTGGCAA GGGGGCGGCGGCGGATGCCGGAAGAGTGCCCGCCCCGCCGCTTGGCGGCCCCTGGATCGAGATGAGCGCCTCCGCGTCGGTCGGGGGCCC CGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAGCG GCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTTACACTTCACTT GTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGTCTCGATTTTGG AATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGA ATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGG ATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTC TTACGATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATTGGAAAGGAAAT TGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTGCAGTTAAAAATTTTGGTGCTTCAGAATGA ACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTTC AGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTCTTCTTGAAGAC TAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACTT TGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTATACTGCACATCT GGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAA TGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTG CCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACT GATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTA AATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAA ATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAG AAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAA TGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAA AGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGC TTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAA AGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTT AATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGT TTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAG CGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGT GGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATC CATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGAC ACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGG ACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAG AATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTT >In-frame_UVRAG_ENST00000528420_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_2857nt AGTGCTCAGCTCCCTTGCCATGCGATACCCTGCAAGTCCTCACCAGCAAAAAGGCTCTCACCAGAGGCTGCCCCTCGGCCTGTGTTATCA GATTTTTTGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTT ACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGT CTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAG CTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGG CTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGT GTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATT GGAAAGGAAATTGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTGCAGTTAAAAATTTTGGTG CTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGA AGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTC TTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACAT AAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTAT ACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAA GACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTA GCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATT CACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGG ATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTG AAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCA CCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGG AAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAG GGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGC CAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTT TTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAA CTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCT ATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTT CTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCT GGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGAC CATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATA AACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCC GCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGT TGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATA >In-frame_UVRAG_ENST00000533454_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_2511nt ACTACCCACAAGAGGTGGTGAAAACGATCTCTGGTATAAAGCAAATGGAAAAGGCTTCATAGAGCCCAGTGTGCAATTAAACAGACTCAG GTAACTGTTCAGAAAATTGGAAAGGAAATTGAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTG CAGTTAAAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATT GCATTACAAGACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGC ACTGCAAAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCT ATTGATTTGAATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGGCATGATTTCTTGGAAAGGA GAGTCCATATGTCAAACAATGTCTCATTGAGAACATGGAATGATTCCATAGATGCTGTGGCAGTGATTAGAGTCTTAAATATTTTGTCCT GTCTGGATCAGTGGGTGCTTGGTTCCTTAACAAATCAGCTGCCTCAGTGATTGGGAAGGCAGGATGCAAAAGATGATGGAAGCATTGCTG TTGCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTA GATCAACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATA AGAACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATA AGGATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAA GTTATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAG CATTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAG TGTGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAG ATCACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAA CAATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCC TCCTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTG ACCTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATG ATGTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCT AGGCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAG AAAACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTG GTGTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCT GTGTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAA CTCAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCC CTTGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACA AGAGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTC >In-frame_UVRAG_ENST00000531818_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_2689nt CAGTTCGAGCTTCTGGGCAGCTTTGTTTACCTGCTCAAGCCTCAGCATTGGTGGGCGCCCCTCCCCCAGCCTCGCTGCCGCCTTGCAGTT TGATCTCAGACTGCTGTGCTAGCAGTGAGCAAGGCTCCGTGGGCGTGGGACCCTCTGAGCCAGGCGCGGGATATAATCTTCTGGTATGCT GTTTGCTAAGACCTTTGGAAAAGCACAGTATTAGGGTGGGAGTGACCTGATTTTCCGGGTGCGATTTTCCAGGTGCCGTCTGTCGTGGCT TCCCTTGGCTGGGAAAGGGAGTTCCCCGACCCCTTGTGCTTCCCTGGTGAGGCGATGCCTTGCCCTGCTTTGGCTCACGGTCCGTGGGCT GCACCCACTGTCCTACAAGCCCCAGTGAGATGAACCCGGCACCTCAATTGGAAATGCAGAAATCATCCATCTTCTGCGTCGCTCACGCTG GAAGCTGTAGACTGGAGCTATTCCTATTCGGCCATCTTGGAACCTCCCTGCCTCTTTTTTCTGAAAAAAAAAAGTGAATGCCTGCAGTTA AAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTA CAAGACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCA AAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGAT TTGAATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTT GCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGA TCAACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAG AACAAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAG GATTCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGT TATGATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCA TTATTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTG TGATGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGAT CACTATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACA ATGAAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTC CTTGCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGAC CTTGGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGAT GTTTGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAG GCGGGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAA AACAGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGT GTCTTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGT GTCCCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACT CAGTGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCT TGAGCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAG AGGAAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGG >In-frame_UVRAG_ENST00000532130_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_2236nt TTTAGTAGAATTCACTGTGAAACCAACTAGACCTTTTTTTTTTCTCCCCTGTTTCTGAAGAAAAAAAAAAGTGAATGCCTGCAGTTAAAA ATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAA GACAAAGGAAGTGCATTTTCAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAA AGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTG AATGAACATAAGGATTACTTTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATTGCTGTTGCC CTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCA ACAATCAAAGACAATATCAATGACAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAAC AAAACATTAGCATTTCTCTGCCGTGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGAT TCACAGATTCACATACGACTGATCTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTAT GATATTTGGATGGATTTTTAAATTCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTA TTCAAACTGAAAGTGGAAAAATTTAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGA TGTAAACCACCTCTATCCAGAAATATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCAC TATTAGTGGAAAATACCAAATGGACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATG AAGACGAAGGGAGTAAATAAAGGAAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTT GCAAGTTGCCAAATAATAGCTTAGGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTT GGTGAATTTTTTTCCCCAAAAGCATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTT TGGCCTGAACTGTGGGCTTTAATTGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCG GGGTCCCCTATTTCTTCTGTTTCTCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAAC AGTTCCTTTCTGATGGGGAGCGTCTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTC TTGTAGCCTGGTTACGAAGTGGGACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTC CCTAACGACCATAGGCAATCCATCTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAG TGAGCAATAAACAAAATGACACAGAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGA GCAGGGCCCGCTCAGGAGGGACCAGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGG AAAGGGGGTTGGATGGGAAGAATCTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATG >In-frame_UVRAG_ENST00000539288_chr11_75728024_+_ZMAT4_ENST00000315769_chr8_40389757_-_2303nt AACTGGAACGGCAGAAGAAAGCTTTGGGACGGGAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTT CAGCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGCACTGCAAAAAGAGAACTCTTCTTGAAGA CTAATGCTCAGTTGACAATTCGTTGCAGGCAGTTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACT TTGTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGGCATGATTTCTTGGAAAGGAGAGTCCATATGTCAAACAATGTCTCATT GAGAACATGGAATGATTCCATAGATGCTGTGGCAGTGATTAGAGTCTTAAATATTTTGTCCTGTCTGGATCAGTGGGTGCTTGGTTCCTT AACAAATCAGCTGCCTCAGTGATTGGGAAGGCAGGATGCAAAAGATGATGGAAGCATTGCTGTTGCCCTTGGTTATACTGCACATCTGGT CTCCATGATTTCCTTTTTCCTACAAGTGCCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAATGA CAAACTGACGGAAAAGGAGAGAGACCTGAAGAATAAGTAGTGAAAGCATCAATCAAGACATAAGAACAAAACATTAGCATTTCTCTGCCG TGGAGAATTGCTTATCAACCACCAGAGGAGGCTTCTTTCTTGAACAATAAACATTTCTTATAAGGATTCACAGATTCACATACGACTGAT CTTGATTTTTGGAAATGAATGAGGTTTCTTTTTTCTTTTTCCTTTTTTTAATTTTGGGGTAAGTTATGATATTTGGATGGATTTTTAAAT TCTTTCCTGATAACATATTTAGCACATGTTCTAAATTATAATCCTATAGCAAACAGTTGGAGCATTATTCAAACTGAAAGTGGAAAAATT TAAATTTCCAATTTATTCTAGATTTCCTCAGAGCATAATTATTCTGTTAAATCCTCAATGAGTGTGATGTAAACCACCTCTATCCAGAAA TATACATTCTTTTCTCATCATGTTGGACACAGTTGAGGGTGACATGCACAGAACTGGAACAGATCACTATTAGTGGAAAATACCAAATGG ACAAATAAATACCAGTCGTTTTCTCCGTTCTCCAAGCACAGGAGCCAGGTTTACCATCTGAACAATGAAGACGAAGGGAGTAAATAAAGG AAGAATTCTCATCTTTTTTCCTGATCATTCAAAGAACAGTTTCTCAAGGTTAAGCCAAGTCCTCCTTGCAAGTTGCCAAATAATAGCTTA GGAAAAGAATTAGTCTGCCTGCATGATGATCTTCTTAGGCAAAAACGTCTTCACAGCCCTTGACCTTGGTGAATTTTTTTCCCCAAAAGC ATCCAAAAGAAGAATTATAAACCCCAGAATGAGATGGAAATAAACAAGTATTTTTTTTTATGATGTTTGGCCTGAACTGTGGGCTTTAAT TGGGGGATACTGATCGTTTGGAAAGAAGTGAGAAAATTCTGAAGAAATGGCGGCCTTGGGCTAGGCGGGGTCCCCTATTTCTTCTGTTTC TCACTGAAGTCCTACTGCTGAGCCAAGACTCAGTCACTCTGGAAAGAGCATGACCGATAAAGAAAACAGTTCCTTTCTGATGGGGAGCGT CTGAGTGCAGATCATGAGGCTCTTTCTCTAGGTTTAATTCTTTTCCATGGTGACCGGACTTGGTGTCTTGTAGCCTGGTTACGAAGTGGG ACGTTGAGCTTCTACTGACGATGCCCTGCATGGACCAGCTGGGATCTGGCTGGGGCTGCCCTGTGTCCCTAACGACCATAGGCAATCCAT CTTCTTGTGTCAGCAATTTCTGGACACCCACTGTTTTCCACCAAGAGCTGAGGTGGCAACAACTCAGTGAGCAATAAACAAAATGACACA GAAATGCACAGTGTTGTTATGAAGGAGCCTGTTTACCTGTGTTCAAAATCTGGCACCATTCCCTTGAGCAGGGCCCGCTCAGGAGGGACC AGGTCTGCCAGTTTCTGTGCCTGCAGAGAGACGAAGCCCCACGAGCCACACCCTACTCTACAAGAGGAAAGGGGGTTGGATGGGAAGAAT CTATTTTGCTGTTTTGGAAAGCACACAGCCGACCTACAAACCTCCTGTGATGGTGTTTCTTCGGATGTGTAAAATAAGGCTTTATTTGTC |
Top |
FusionGenePPI for UVRAG_ZMAT4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UVRAG | BECN1, PIK3C3, VPS33A, VPS18, PIK3R4, PTPRA, KIAA0226, TGFBRAP1, VPS16, VPS11, VPS33B, VPS39, YWHAE, RALB, USP18, XPO1, MYO1C, DDB1, DDB2, CUL4A, RBX1, KIAA0226L | ZMAT4 | APP, SRPK2, HECW2, CUL3, FAM26D, DSG4, HEPHL1, LYG2, S100A3, VSIG8, NEU2, TRIM29, LRRC15 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for UVRAG_ZMAT4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for UVRAG_ZMAT4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|