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Fusion gene ID: 41290 |
FusionGeneSummary for UVRAG_INTS4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UVRAG_INTS4 | Fusion gene ID: 41290 | Hgene | Tgene | Gene symbol | UVRAG | INTS4 | Gene ID | 7405 | 92105 |
| Gene name | UV radiation resistance associated | integrator complex subunit 4 | |
| Synonyms | DHTX|VPS38|p63 | INT4|MST093 | |
| Cytomap | 11q13.5 | 11q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UV radiation resistance-associated gene proteinbeclin 1 binding proteindisrupted in heterotaxy | integrator complex subunit 4MSTP093 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9P2Y5 | Q96HW7 | |
| Ensembl transtripts involved in fusion gene | ENST00000356136, ENST00000528420, ENST00000533454, ENST00000531818, ENST00000532130, ENST00000539288, ENST00000525872, ENST00000538870, | ENST00000534064, ENST00000535943, ENST00000525931, ENST00000529807, ENST00000527522, | |
| Fusion gene scores | * DoF score | 29 X 10 X 12=3480 | 6 X 4 X 5=120 |
| # samples | 29 | 7 | |
| ** MAII score | log2(29/3480*10)=-3.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UVRAG [Title/Abstract] AND INTS4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UVRAG | GO:0071900 | regulation of protein serine/threonine kinase activity | 22542840 |
| Hgene | UVRAG | GO:0097680 | double-strand break repair via classical nonhomologous end joining | 22542840 |
| Tgene | INTS4 | GO:0016180 | snRNA processing | 16239144 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A1-A0SJ-01A | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000356136 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| In-frame | ENST00000356136 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000356136 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000356136 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000356136 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| In-frame | ENST00000528420 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| In-frame | ENST00000528420 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000528420 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000528420 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 5CDS-intron | ENST00000528420 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000533454 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000533454 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000533454 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000533454 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000533454 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000531818 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000531818 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000531818 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000531818 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000531818 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000532130 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000532130 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000532130 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000532130 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000532130 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000539288 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000539288 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000539288 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000539288 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000539288 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 3UTR-3CDS | ENST00000525872 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 3UTR-3CDS | ENST00000525872 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 3UTR-intron | ENST00000525872 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 3UTR-intron | ENST00000525872 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| 3UTR-intron | ENST00000525872 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000538870 | ENST00000534064 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-3CDS | ENST00000538870 | ENST00000535943 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000538870 | ENST00000525931 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000538870 | ENST00000529807 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
| intron-intron | ENST00000538870 | ENST00000527522 | UVRAG | chr11 | 75623083 | + | INTS4 | chr11 | 77618856 | - |
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FusionProtFeatures for UVRAG_INTS4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UVRAG | INTS4 |
| Versatile protein that is involved in regulation ofdifferent cellular pathways implicated in membrane trafficking.Involved in regulation of the COPI-dependent retrograde transportfrom Golgi and the endoplasmic reticulum by associating with theNRZ complex; the function is dependent on its binding tophosphatidylinositol 3-phosphate (PtdIns(3)P) (PubMed:24056303).During autophagy acts as regulatory subunit of the alternativePI3K complex II (PI3KC3-C2) that mediates formation ofphosphatidylinositol 3-phosphate and is believed to be involved inmaturation of autophagosomes and endocytosis. Activates lipidkinase activity of PIK3C3. Involved in the regulation ofdegradative endocytic trafficking and cytokinesis, and inregulation of ATG9A transport from the Golgi to the autophagosome;the functions seems to implicate its association with PI3KC3-C2(PubMed:16799551, PubMed:20643123, PubMed:24056303). Involved inmaturation of autophagosomes and degradative endocytic traffickingindependently of BECN1 but depending on its association with aclass C Vps complex (possibly the HOPS complex); the associationis also proposed to promote autophagosome recruitment andactivation of Rab7 and endosome-endosome fusion events(PubMed:18552835). Enhances class C Vps complex (possibly HOPScomplex) association with a SNARE complex and promotes fusogenicSNARE complex formation during late endocytic membrane fusion(PubMed:24550300). In case of negative-strand RNA virus infectionis required for efficient virus entry, promotes endocytictransport of virions and is implicated in a VAMP8-specificfusogenic SNARE complex assembly (PubMed:24550300).{ECO:0000269|PubMed:18552835, ECO:0000269|PubMed:20643123,ECO:0000269|PubMed:24056303, ECO:0000305}. Involved in maintaining chromosomal stability. PromotesDNA double-strand break (DSB) repair by association with DNA-dependent protein kinase complex DNA-PK and activating it in non-homologous end joining (NHEJ) (PubMed:22542840). Required forcentrosome stability and proper chromosome segregation(PubMed:22542840). {ECO:0000269|PubMed:22542840}. | Component of the Integrator (INT) complex, a complexinvolved in the small nuclear RNAs (snRNA) U1 and U2 transcriptionand in their 3'-box-dependent processing. The Integrator complexis associated with the C-terminal domain (CTD) of RNA polymeraseII largest subunit (POLR2A) and is recruited to the U1 and U2snRNAs genes (Probable). Mediates recruitment of cytoplasmicdynein to the nuclear envelope, probably as component of the INTcomplex (PubMed:23904267). {ECO:0000269|PubMed:23904267,ECO:0000305|PubMed:16239144}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | UVRAG | chr11:75623083 | chr11:77618856 | ENST00000356136 | + | 6 | 15 | 44_128 | 197 | 700 | Domain | Note=C2 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 145_183 | -8 | 506 | Repeat | Note=HEAT 2 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 190_228 | -8 | 506 | Repeat | Note=HEAT 3 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 229_263 | -8 | 506 | Repeat | Note=HEAT 4 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 277_313 | -8 | 506 | Repeat | Note=HEAT 5 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 369_405 | -8 | 506 | Repeat | Note=HEAT 6 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 406_444 | -8 | 506 | Repeat | Note=HEAT 7 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 446_484 | -8 | 506 | Repeat | Note=HEAT 8 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000529807 | - | 0 | 12 | 66_105 | -8 | 506 | Repeat | Note=HEAT 1 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 145_183 | 15 | 339 | Repeat | Note=HEAT 2 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 190_228 | 15 | 339 | Repeat | Note=HEAT 3 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 229_263 | 15 | 339 | Repeat | Note=HEAT 4 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 277_313 | 15 | 339 | Repeat | Note=HEAT 5 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 369_405 | 15 | 339 | Repeat | Note=HEAT 6 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 406_444 | 15 | 339 | Repeat | Note=HEAT 7 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 446_484 | 15 | 339 | Repeat | Note=HEAT 8 |
| Tgene | >INTS4 | chr11:75623083 | chr11:77618856 | ENST00000535943 | - | 0 | 9 | 66_105 | 15 | 339 | Repeat | Note=HEAT 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >UVRAG | chr11:75623083 | chr11:77618856 | ENST00000356136 | + | 6 | 15 | 224_305 | 197 | 700 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 145_183 | 640 | 964 | Repeat | Note=HEAT 2 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 190_228 | 640 | 964 | Repeat | Note=HEAT 3 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 229_263 | 640 | 964 | Repeat | Note=HEAT 4 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 277_313 | 640 | 964 | Repeat | Note=HEAT 5 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 369_405 | 640 | 964 | Repeat | Note=HEAT 6 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 406_444 | 640 | 964 | Repeat | Note=HEAT 7 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 446_484 | 640 | 964 | Repeat | Note=HEAT 8 |
| Tgene | INTS4 | chr11:75623083 | chr11:77618856 | ENST00000534064 | - | 14 | 23 | 66_105 | 640 | 964 | Repeat | Note=HEAT 1 |
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FusionGeneSequence for UVRAG_INTS4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_521aa MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSL NPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILL QVDQNCVRNSYDVFSLLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSG VENKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTML RQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLI >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_521aa MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSL NPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILL QVDQNCVRNSYDVFSLLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSG VENKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTML RQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLI >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_420aa MPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSY DVFSLLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHH MRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLHLPLP EQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWT >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_420aa MPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSY DVFSLLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHH MRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLHLPLP EQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_1563nt ATGAGCGCCTCCGCGTCGGTCGGGGGCCCCGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCC CTGCATGTGGAGCTGCCGTCTCAGCAGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAG CTCCTTGATACCTACTTTACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTG AATCCCACGTGGCGAAGTCTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGA AAGGAGAACATCTACCAGCTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAA AATGAAATAATTTTTGGGCTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTG CAGGTGGATCAGAACTGTGTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTG GCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCC CCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGT GTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGA CTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAG GACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTG CGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAAC CCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTC CAGGTCTTATATCCAGATGGCCAGGCTCAGATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATC ACTCAGGTTTATCTCTCCCACACCGCTTGGACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATT CCAAAATGCCCCTGGATGGAGGGTGGTGAGATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAA >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_1563nt ATGAGCGCCTCCGCGTCGGTCGGGGGCCCCGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCC CTGCATGTGGAGCTGCCGTCTCAGCAGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAG CTCCTTGATACCTACTTTACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTG AATCCCACGTGGCGAAGTCTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGA AAGGAGAACATCTACCAGCTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAA AATGAAATAATTTTTGGGCTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTG CAGGTGGATCAGAACTGTGTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTG GCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCC CCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGT GTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGA CTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAG GACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTG CGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAAC CCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTC CAGGTCTTATATCCAGATGGCCAGGCTCAGATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATC ACTCAGGTTTATCTCTCCCACACCGCTTGGACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATT CCAAAATGCCCCTGGATGGAGGGTGGTGAGATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAA >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_1260nt ATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGAATGG AAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGGATAC TATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTCTTAC GATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTT CGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCA GCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCAC ATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTT TTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATG CCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCA GAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCC CTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGATGGCCAGGCTCAGATG ATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCCCACACCGCTTGGACA GAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATGGAGGGTGGTGAGATG TCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAACCTGCACGGCGCTAA >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_1260nt ATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGAATGG AAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGGATAC TATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTCTTAC GATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTT CGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCA GCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCAC ATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTT TTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATG CCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCA GAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCC CTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGATGGCCAGGCTCAGATG ATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCCCACACCGCTTGGACA GAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATGGAGGGTGGTGAGATG TCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAACCTGCACGGCGCTAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_2033nt AATGAGCGCTCCGGGTCTCAGCGGGGTGGAGGGGTTGCACTGCGGTAATATGGCTCTTCCTTAGCCAGCGGCGGCAACGGCGGCAGCGGC GGCAGCGGCGGCGGCTACTGTCTGGGCTGAGCAGTAGTGCCTCTCGGGTGGCGGGTTTCTAGGCTGCAGGGGCTTGGTAGGTGGTGGCAA GGGGGCGGCGGCGGATGCCGGAAGAGTGCCCGCCCCGCCGCTTGGCGGCCCCTGGATCGAGATGAGCGCCTCCGCGTCGGTCGGGGGCCC CGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAGCG GCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTTACACTTCACTT GTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGTCTCGATTTTGG AATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGA ATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGG ATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTC TTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTA TCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGC CTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACA TCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAA ATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCT TATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCT TCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGT TGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGATGGCCAGGCTCA GATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCCCACACCGCTTG GACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATGGAGGGTGGTGA GATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAACCTGCACGGCG CTAAGGCAAAAACAGTCTTCCCAACCGTGGCCTAGAGGGCCCTTCTTAGGTGTCAGAATGAGCCAAGCCTGAAGCACTTCACCTGGAATT GATGTGTAGGCTTAAGGAGTATGTGACCCTTACAGTCTCATCTGGTATCAAACACAGGATAAATTGTTTCTTCATTAAAAAATAAAAAAC >In-frame_UVRAG_ENST00000356136_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_2031nt AATGAGCGCTCCGGGTCTCAGCGGGGTGGAGGGGTTGCACTGCGGTAATATGGCTCTTCCTTAGCCAGCGGCGGCAACGGCGGCAGCGGC GGCAGCGGCGGCGGCTACTGTCTGGGCTGAGCAGTAGTGCCTCTCGGGTGGCGGGTTTCTAGGCTGCAGGGGCTTGGTAGGTGGTGGCAA GGGGGCGGCGGCGGATGCCGGAAGAGTGCCCGCCCCGCCGCTTGGCGGCCCCTGGATCGAGATGAGCGCCTCCGCGTCGGTCGGGGGCCC CGTCCCCCAGCCACCCCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAGCG GCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTTACACTTCACTT GTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGTCTCGATTTTGG AATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGA ATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGG ATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGTGTTCGCAATTC TTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTA TCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGC CTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACA TCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAA ATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCT TATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCT TCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGT TGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGATGGCCAGGCTCA GATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCCCACACCGCTTG GACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATGGAGGGTGGTGA GATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAACCTGCACGGCG CTAAGGCAAAAACAGTCTTCCCAACCGTGGCCTAGAGGGCCCTTCTTAGGTGTCAGAATGAGCCAAGCCTGAAGCACTTCACCTGGAATT GATGTGTAGGCTTAAGGAGTATGTGACCCTTACAGTCTCATCTGGTATCAAACACAGGATAAATTGTTTCTTCATTAAAAAATAAAAAAC >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000534064_chr11_77618856_-_1774nt AGTGCTCAGCTCCCTTGCCATGCGATACCCTGCAAGTCCTCACCAGCAAAAAGGCTCTCACCAGAGGCTGCCCCTCGGCCTGTGTTATCA GATTTTTTGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTT ACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGT CTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAG CTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGG CTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGT GTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTC TCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAG AGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTG GTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGG ATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAA CTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTG CATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCT GGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGAT GGCCAGGCTCAGATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCC CACACCGCTTGGACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATG GAGGGTGGTGAGATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAA CCTGCACGGCGCTAAGGCAAAAACAGTCTTCCCAACCGTGGCCTAGAGGGCCCTTCTTAGGTGTCAGAATGAGCCAAGCCTGAAGCACTT CACCTGGAATTGATGTGTAGGCTTAAGGAGTATGTGACCCTTACAGTCTCATCTGGTATCAAACACAGGATAAATTGTTTCTTCATTAAA >In-frame_UVRAG_ENST00000528420_chr11_75623083_+_INTS4_ENST00000535943_chr11_77618856_-_1772nt AGTGCTCAGCTCCCTTGCCATGCGATACCCTGCAAGTCCTCACCAGCAAAAAGGCTCTCACCAGAGGCTGCCCCTCGGCCTGTGTTATCA GATTTTTTGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAGCTCCTTGATACCTACTTT ACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGT CTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGAAAGGAGAACATCTACCAG CTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGG CTGAATGATGGATACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTGCAGGTGGATCAGAACTGT GTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTC TCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAG AGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTG GTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGG ATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAA CTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTG CATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCT GGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGGTCTTATATCCAGAT GGCCAGGCTCAGATGATTCACCCCAAGCCTGCAGACTTCCGGAATCCTGGCCCAGGGCGGCACCGGCTCATCACTCAGGTTTATCTCTCC CACACCGCTTGGACAGAGGCATGCCAGGTGGAAGTGAGGCTGCTGCTGGCCTACAACTCCAGTGCTCGCATTCCAAAATGCCCCTGGATG GAGGGTGGTGAGATGTCACCACAGGTGGAAACCAGCATCGAGGGCACCATTCCCTTCAGCAAGCCTGTAAAAGTTTATATAATGCCCAAA CCTGCACGGCGCTAAGGCAAAAACAGTCTTCCCAACCGTGGCCTAGAGGGCCCTTCTTAGGTGTCAGAATGAGCCAAGCCTGAAGCACTT CACCTGGAATTGATGTGTAGGCTTAAGGAGTATGTGACCCTTACAGTCTCATCTGGTATCAAACACAGGATAAATTGTTTCTTCATTAAA |
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FusionGenePPI for UVRAG_INTS4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UVRAG | BECN1, PIK3C3, VPS33A, VPS18, PIK3R4, PTPRA, KIAA0226, TGFBRAP1, VPS16, VPS11, VPS33B, VPS39, YWHAE, RALB, USP18, XPO1, MYO1C, DDB1, DDB2, CUL4A, RBX1, KIAA0226L | INTS4 | RPAP2, INTS1, INTS3, INTS5, INTS6, SHFM1, INTS10, INTS9, HECW2, HGS, ZMIZ2, USHBP1, HLA-B, SLAMF1, VSIG4, LOC554223, ISLR, INTS4P2, TGOLN2, FAF2, C7orf26, CPSF3L, FAM98A, ASUN, NTRK1, PPP2CA, PPP2CB, PPP2R1A, VWA9, SIGLECL1, BMP2K, VSIG1, PMEL, PDCD1, CD70, GORASP1, AP2A1, CD79B, SIGLEC5, ADAM32, PCDHA12, AP2A2, CLEC2D |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UVRAG_INTS4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UVRAG_INTS4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | INTS4 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
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