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Fusion gene ID: 40702 |
FusionGeneSummary for UGDH_RPL7L1 |
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Fusion gene information | Fusion gene name: UGDH_RPL7L1 | Fusion gene ID: 40702 | Hgene | Tgene | Gene symbol | UGDH | RPL7L1 | Gene ID | 7358 | 285855 |
Gene name | UDP-glucose 6-dehydrogenase | ribosomal protein L7 like 1 | |
Synonyms | GDH|UDP-GlcDH|UDPGDH|UGD | dJ475N16.4 | |
Cytomap | 4p14 | 6p21.1 | |
Type of gene | protein-coding | protein-coding | |
Description | UDP-glucose 6-dehydrogenaseUDP-Glc dehydrogenaseUDP-glucose dehydrogenaseuridine diphospho-glucose dehydrogenase | 60S ribosomal protein L7-like 1large ribosomal subunit protein uL30-like 1 | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | O60701 | Q6DKI1 | |
Ensembl transtripts involved in fusion gene | ENST00000316423, ENST00000501493, ENST00000506179, ENST00000507089, ENST00000515398, | ENST00000493763, ENST00000397415, ENST00000304734, ENST00000424341, ENST00000602561, | |
Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 3 X 3 X 2=18 |
# samples | 3 | 3 | |
** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: UGDH [Title/Abstract] AND RPL7L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AW733157 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3UTR | ENST00000316423 | ENST00000493763 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000316423 | ENST00000397415 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000316423 | ENST00000304734 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000316423 | ENST00000424341 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000316423 | ENST00000602561 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000501493 | ENST00000493763 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000501493 | ENST00000397415 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000501493 | ENST00000304734 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000501493 | ENST00000424341 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000501493 | ENST00000602561 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000506179 | ENST00000493763 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000506179 | ENST00000397415 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000506179 | ENST00000304734 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000506179 | ENST00000424341 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000506179 | ENST00000602561 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000507089 | ENST00000493763 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000507089 | ENST00000397415 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000507089 | ENST00000304734 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000507089 | ENST00000424341 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000507089 | ENST00000602561 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000515398 | ENST00000493763 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000515398 | ENST00000397415 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000515398 | ENST00000304734 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-3UTR | ENST00000515398 | ENST00000424341 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
intron-intron | ENST00000515398 | ENST00000602561 | UGDH | chr4 | 39501397 | + | RPL7L1 | chr6 | 42854448 | - |
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FusionProtFeatures for UGDH_RPL7L1 |
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Hgene | Tgene |
UGDH | RPL7L1 |
Involved in the biosynthesis of glycosaminoglycans;hyaluronan, chondroitin sulfate, and heparan sulfate. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for UGDH_RPL7L1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for UGDH_RPL7L1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UGDH_RPL7L1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UGDH_RPL7L1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | UGDH | C0023903 | Liver neoplasms | 1 | CTD_human |