![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 40700 |
FusionGeneSummary for UGDH-AS1_RNF121 |
![]() |
Fusion gene information | Fusion gene name: UGDH-AS1_RNF121 | Fusion gene ID: 40700 | Hgene | Tgene | Gene symbol | UGDH-AS1 | RNF121 | Gene ID | 100885776 | 55298 |
Gene name | UGDH antisense RNA 1 | ring finger protein 121 | |
Synonyms | - | - | |
Cytomap | 4p14 | 11q13.4 | |
Type of gene | ncRNA | protein-coding | |
Description | UGDH antisense RNA 1 (non-protein coding) | RING finger protein 121 | |
Modification date | 20180329 | 20180523 | |
UniProtAcc | Q9H920 | ||
Ensembl transtripts involved in fusion gene | ENST00000504032, | ENST00000361756, ENST00000533380, ENST00000393713, ENST00000490867, ENST00000545854, ENST00000530137, | |
Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 5 X 5 X 3=75 |
# samples | 3 | 6 | |
** MAII score | log2(3/4*10)=2.90689059560852 | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: UGDH-AS1 [Title/Abstract] AND RNF121 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AI005126 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - | ||
ChiTaRS3.1 | AI239943 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000504032 | ENST00000361756 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
intron-intron | ENST00000504032 | ENST00000533380 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
intron-intron | ENST00000504032 | ENST00000393713 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
intron-intron | ENST00000504032 | ENST00000490867 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
intron-intron | ENST00000504032 | ENST00000545854 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
intron-intron | ENST00000504032 | ENST00000530137 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
Top |
FusionProtFeatures for UGDH-AS1_RNF121 |
![]() |
Hgene | Tgene |
UGDH-AS1 | RNF121 |
Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for UGDH-AS1_RNF121 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for UGDH-AS1_RNF121 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for UGDH-AS1_RNF121 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for UGDH-AS1_RNF121 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |