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Fusion gene ID: 40648 |
FusionGeneSummary for UBXN6_GRM4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBXN6_GRM4 | Fusion gene ID: 40648 | Hgene | Tgene | Gene symbol | UBXN6 | GRM4 | Gene ID | 80700 | 2914 |
| Gene name | UBX domain protein 6 | glutamate metabotropic receptor 4 | |
| Synonyms | UBXD1|UBXDC2 | GPRC1D|MGLUR4|mGlu4 | |
| Cytomap | 19p13.3 | 6p21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UBX domain-containing protein 6CTB-50L17.16UBX domain containing 1UBX domain-containing 2UBX domain-containing protein 1 | metabotropic glutamate receptor 4glutamate receptor, metabotropic 4 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9BZV1 | Q14833 | |
| Ensembl transtripts involved in fusion gene | ENST00000301281, ENST00000394765, | ENST00000538487, ENST00000374181, ENST00000374177, ENST00000544773, ENST00000545715, ENST00000535756, ENST00000609222, ENST00000455714, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 5 X 5 X 4=100 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/100*10)=-0.736965594166206 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UBXN6 [Title/Abstract] AND GRM4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | GRM4 | GO:0000187 | activation of MAPK activity | 15102938 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-29-1783-01A | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000301281 | ENST00000538487 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| Frame-shift | ENST00000301281 | ENST00000374181 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| Frame-shift | ENST00000301281 | ENST00000374177 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| Frame-shift | ENST00000301281 | ENST00000544773 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000301281 | ENST00000545715 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000301281 | ENST00000535756 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000301281 | ENST00000609222 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000301281 | ENST00000455714 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| In-frame | ENST00000394765 | ENST00000538487 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| In-frame | ENST00000394765 | ENST00000374181 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| In-frame | ENST00000394765 | ENST00000374177 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| In-frame | ENST00000394765 | ENST00000544773 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000394765 | ENST00000545715 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000394765 | ENST00000535756 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000394765 | ENST00000609222 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
| 5CDS-5UTR | ENST00000394765 | ENST00000455714 | UBXN6 | chr19 | 4452361 | - | GRM4 | chr6 | 34008525 | - |
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FusionProtFeatures for UBXN6_GRM4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBXN6 | GRM4 |
| May negatively regulate the ATPase activity of VCP, anATP-driven segregase that associates with different cofactors tocontrol a wide variety of cellular processes (PubMed:26475856). Asa cofactor of VCP, it may play a role in the transport of CAV1 tolysosomes for degradation (PubMed:21822278, PubMed:23335559). Itmay also play a role in endoplasmic reticulum-associateddegradation (ERAD) of misfolded proteins (PubMed:19275885).Together with VCP and other cofactors, it may play a role inmacroautophagy, regulating for instance the clearance of damagedlysosomes (PubMed:27753622). {ECO:0000269|PubMed:19275885,ECO:0000269|PubMed:21822278, ECO:0000269|PubMed:23335559,ECO:0000269|PubMed:26475856, ECO:0000269|PubMed:27753622}. | G-protein coupled receptor for glutamate. Ligand bindingcauses a conformation change that triggers signaling via guaninenucleotide-binding proteins (G proteins) and modulates theactivity of down-stream effectors. Signaling inhibits adenylatecyclase activity. {ECO:0000269|PubMed:7617140,ECO:0000269|PubMed:8738157, ECO:0000269|PubMed:9473604}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for UBXN6_GRM4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000538487_chr6_34008525_-_617aa MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKE AILLTVSELGRIQLMSRRGRCSLXSMPCTPWATRCTPCTVTCVPAAWGSARAWTLXMAPSCLSTSETSTSQASQGTLXPSMRMEMRLGAM TSTNTSCATILPSTRSLAPGLTTCTLEXSGCTGRGAGSSCPAPSAACPANRVSGRRQXRACLAAGTASLAQGTSTRWTATPVRRVPMTCG PQRTARAAGPSPSSSLSGARPGPCCPSSWPWWASLPRCSWXSPLCATTTRPSSRPRAVNXATCCWQASSCAMPPPSSXSLSPTLAPARCA ESSWDXGXASAMQPCSPRPTASTASSSRASARSVPHASSAPPHSWPSPSASSRCSCWASVCGLWWTPPTRWWTSRTSGHSTPASPGVCSS VTSRTCRSSACWATACCSWSRAPCMPSRHAACPRPSMRPSPLASPCTPLASSGWPSSPSSLAPRSRPTSCTSRRRRXRSRXVXAPRCPWE >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374181_chr6_34008525_-_617aa MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKE AILLTVSELGRIQLMSRRGRCSLXSMPCTPWATRCTPCTVTCVPAAWGSARAWTLXMAPSCLSTSETSTSQASQGTLXPSMRMEMRLGAM TSTNTSCATILPSTRSLAPGLTTCTLEXSGCTGRGAGSSCPAPSAACPANRVSGRRQXRACLAAGTASLAQGTSTRWTATPVRRVPMTCG PQRTARAAGPSPSSSLSGARPGPCCPSSWPWWASLPRCSWXSPLCATTTRPSSRPRAVNXATCCWQASSCAMPPPSSXSLSPTLAPARCA ESSWDXGXASAMQPCSPRPTASTASSSRASARSVPHASSAPPHSWPSPSASSRCSCWASVCGLWWTPPTRWWTSRTSGHSTPASPGVCSS VTSRTCRSSACWATACCSWSRAPCMPSRHAACPRPSMRPSPLASPCTPLASSGWPSSPSSLAPRSRPTSCTSRRRRXRSRXVXAPRCPWE >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374177_chr6_34008525_-_617aa MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKE AILLTVSELGRIQLMSRRGRCSLXSMPCTPWATRCTPCTVTCVPAAWGSARAWTLXMAPSCLSTSETSTSQASQGTLXPSMRMEMRLGAM TSTNTSCATILPSTRSLAPGLTTCTLEXSGCTGRGAGSSCPAPSAACPANRVSGRRQXRACLAAGTASLAQGTSTRWTATPVRRVPMTCG PQRTARAAGPSPSSSLSGARPGPCCPSSWPWWASLPRCSWXSPLCATTTRPSSRPRAVNXATCCWQASSCAMPPPSSXSLSPTLAPARCA ESSWDXGXASAMQPCSPRPTASTASSSRASARSVPHASSAPPHSWPSPSASSRCSCWASVCGLWWTPPTRWWTSRTSGHSTPASPGVCSS VTSRTCRSSACWATACCSWSRAPCMPSRHAACPRPSMRPSPLASPCTPLASSGWPSSPSSLAPRSRPTSCTSRRRRXRSRXVXAPRCPWE >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000544773_chr6_34008525_-_617aa MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKE AILLTVSELGRIQLMSRRGRCSLXSMPCTPWATRCTPCTVTCVPAAWGSARAWTLXMAPSCLSTSETSTSQASQGTLXPSMRMEMRLGAM TSTNTSCATILPSTRSLAPGLTTCTLEXSGCTGRGAGSSCPAPSAACPANRVSGRRQXRACLAAGTASLAQGTSTRWTATPVRRVPMTCG PQRTARAAGPSPSSSLSGARPGPCCPSSWPWWASLPRCSWXSPLCATTTRPSSRPRAVNXATCCWQASSCAMPPPSSXSLSPTLAPARCA ESSWDXGXASAMQPCSPRPTASTASSSRASARSVPHASSAPPHSWPSPSASSRCSCWASVCGLWWTPPTRWWTSRTSGHSTPASPGVCSS VTSRTCRSSACWATACCSWSRAPCMPSRHAACPRPSMRPSPLASPCTPLASSGWPSSPSSLAPRSRPTSCTSRRRRXRSRXVXAPRCPWE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000538487_chr6_34008525_-_1853nt ATGGCAGCCGCTGCCGCCCTAGCCCGGCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTG AGAAAGGAACTTCAAGCCGAAGCCACCGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCT GCCCACCTGGCTGTGCCTGGCGTGTACTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAG GCCATTCTCTTGACCGTGAGCGAATTGGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCA TGGGCCACGCGCTGCACGCCATGCACCGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGC TGCTTAAGTACATCCGAAACGTCAACTTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATG ACATCTACCAATACCAGCTGCGCAACGATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGA TGCACTGGCCGGGGAGCGGGCAGCAGCTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCA TGCCTTGCTGCTGGCACTGCGAGCCTTGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGC CCACAGAGAACCGCACGGGCTGCCGGCCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCG TGGTGGGCATCGCTGCCACGTTGTTCGTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGA GCTACGTGCTGCTGGCAGGCATCTTCCTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCC GAATCTTCCTGGGACTAGGGATGAGCATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGC GCTCGGTCAGTGCCCCACGCTTCATCAGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTG TGTGGTTTGTGGTGGACCCCTCCCACTCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGT GTGACATCTCGGACCTGTCGCTCATCTGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCG GCGTGCCCGAGACCTTCAATGAGGCCAAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCT TTGGCACCTCGCAGTCGGCCGACAAGCTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAA TGCTCTACATGCCCAAAGTCTACATCATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGG CGGCCACCATGTCCAACAAGTTCACGCAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCC >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374181_chr6_34008525_-_1853nt ATGGCAGCCGCTGCCGCCCTAGCCCGGCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTG AGAAAGGAACTTCAAGCCGAAGCCACCGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCT GCCCACCTGGCTGTGCCTGGCGTGTACTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAG GCCATTCTCTTGACCGTGAGCGAATTGGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCA TGGGCCACGCGCTGCACGCCATGCACCGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGC TGCTTAAGTACATCCGAAACGTCAACTTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATG ACATCTACCAATACCAGCTGCGCAACGATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGA TGCACTGGCCGGGGAGCGGGCAGCAGCTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCA TGCCTTGCTGCTGGCACTGCGAGCCTTGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGC CCACAGAGAACCGCACGGGCTGCCGGCCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCG TGGTGGGCATCGCTGCCACGTTGTTCGTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGA GCTACGTGCTGCTGGCAGGCATCTTCCTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCC GAATCTTCCTGGGACTAGGGATGAGCATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGC GCTCGGTCAGTGCCCCACGCTTCATCAGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTG TGTGGTTTGTGGTGGACCCCTCCCACTCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGT GTGACATCTCGGACCTGTCGCTCATCTGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCG GCGTGCCCGAGACCTTCAATGAGGCCAAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCT TTGGCACCTCGCAGTCGGCCGACAAGCTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAA TGCTCTACATGCCCAAAGTCTACATCATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGG CGGCCACCATGTCCAACAAGTTCACGCAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCC >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374177_chr6_34008525_-_1853nt ATGGCAGCCGCTGCCGCCCTAGCCCGGCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTG AGAAAGGAACTTCAAGCCGAAGCCACCGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCT GCCCACCTGGCTGTGCCTGGCGTGTACTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAG GCCATTCTCTTGACCGTGAGCGAATTGGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCA TGGGCCACGCGCTGCACGCCATGCACCGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGC TGCTTAAGTACATCCGAAACGTCAACTTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATG ACATCTACCAATACCAGCTGCGCAACGATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGA TGCACTGGCCGGGGAGCGGGCAGCAGCTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCA TGCCTTGCTGCTGGCACTGCGAGCCTTGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGC CCACAGAGAACCGCACGGGCTGCCGGCCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCG TGGTGGGCATCGCTGCCACGTTGTTCGTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGA GCTACGTGCTGCTGGCAGGCATCTTCCTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCC GAATCTTCCTGGGACTAGGGATGAGCATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGC GCTCGGTCAGTGCCCCACGCTTCATCAGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTG TGTGGTTTGTGGTGGACCCCTCCCACTCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGT GTGACATCTCGGACCTGTCGCTCATCTGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCG GCGTGCCCGAGACCTTCAATGAGGCCAAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCT TTGGCACCTCGCAGTCGGCCGACAAGCTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAA TGCTCTACATGCCCAAAGTCTACATCATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGG CGGCCACCATGTCCAACAAGTTCACGCAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCC >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000544773_chr6_34008525_-_1853nt ATGGCAGCCGCTGCCGCCCTAGCCCGGCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTG AGAAAGGAACTTCAAGCCGAAGCCACCGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCT GCCCACCTGGCTGTGCCTGGCGTGTACTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAG GCCATTCTCTTGACCGTGAGCGAATTGGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCA TGGGCCACGCGCTGCACGCCATGCACCGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGC TGCTTAAGTACATCCGAAACGTCAACTTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATG ACATCTACCAATACCAGCTGCGCAACGATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGA TGCACTGGCCGGGGAGCGGGCAGCAGCTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCA TGCCTTGCTGCTGGCACTGCGAGCCTTGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGC CCACAGAGAACCGCACGGGCTGCCGGCCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCG TGGTGGGCATCGCTGCCACGTTGTTCGTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGA GCTACGTGCTGCTGGCAGGCATCTTCCTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCC GAATCTTCCTGGGACTAGGGATGAGCATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGC GCTCGGTCAGTGCCCCACGCTTCATCAGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTG TGTGGTTTGTGGTGGACCCCTCCCACTCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGT GTGACATCTCGGACCTGTCGCTCATCTGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCG GCGTGCCCGAGACCTTCAATGAGGCCAAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCT TTGGCACCTCGCAGTCGGCCGACAAGCTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAA TGCTCTACATGCCCAAAGTCTACATCATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGG CGGCCACCATGTCCAACAAGTTCACGCAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000538487_chr6_34008525_-_2977nt GGAGTATAGGGCTTGAACTGAGAGCCTGGCCTCCCAGAAGGTTTTAATAGACCTACGGCACAGAAATTGACACAGCCCGGAAAAGGCCCA CAAAGAGAAGCCCAACCAGCCAGCCCCCAGGCCGCCCCGCCAGGGACCCACCAATGAGGCACAGATGGCAGCCGCTGCCGCCCTAGCCCG GCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTGAGAAAGGAACTTCAAGCCGAAGCCAC CGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCTGCCCACCTGGCTGTGCCTGGCGTGTA CTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAGGCCATTCTCTTGACCGTGAGCGAATT GGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCATGGGCCACGCGCTGCACGCCATGCAC CGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGCTGCTTAAGTACATCCGAAACGTCAAC TTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATGACATCTACCAATACCAGCTGCGCAAC GATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGATGCACTGGCCGGGGAGCGGGCAGCAG CTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCATGCCTTGCTGCTGGCACTGCGAGCCT TGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGCCCACAGAGAACCGCACGGGCTGCCGG CCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCGTGGTGGGCATCGCTGCCACGTTGTTC GTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGAGCTACGTGCTGCTGGCAGGCATCTTC CTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCCGAATCTTCCTGGGACTAGGGATGAGC ATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGCGCTCGGTCAGTGCCCCACGCTTCATC AGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTGTGTGGTTTGTGGTGGACCCCTCCCAC TCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGTGTGACATCTCGGACCTGTCGCTCATC TGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCGGCGTGCCCGAGACCTTCAATGAGGCC AAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCTTTGGCACCTCGCAGTCGGCCGACAAG CTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAATGCTCTACATGCCCAAAGTCTACATC ATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGGCGGCCACCATGTCCAACAAGTTCACG CAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCCCAGCGCTGGCCACCAAACAGACTTAC GTCACTTACACCAACCATGCAATCTAGCGAGTCCATGGAGCTGAGCAGCAGGAGGAGGAGCCGTGACCCTGTGGAAGGTGCGTCGGGCCA GGGCCACACCCAAGGGCCCAGCTGTCTTGCCTGCCCGTGGGCACCCACGGACGTGGCTTGGTGCTGAGGATAGCAGAGCCCCCAGCCATC ACTGCTGGCAGCCTGGGCAAACCGGGTGAGCAACAGGAGGACGAGGGGCCGGGGCGGTGCCAGGCTACCACAAGAACCTGCGTCTTGGAC CATTGCCCCTCCCGGCCCCAAACCACAGGGGCTCAGGTCGTGTGGGCCCCAGTGCTAGATCTCTCCCTCCCTTCGTCTCTGTCTGTGCTG TTGGCGACCCCTCTGTCTGTCTCCAGCCCTGTCTTTCTGTTCTCTTATCTCTTTGTTTCACCTTTTCCCTCTCTGGCGTCCCCGGCTGCT TGTACTCTTGGCCTTTTCTGTGTCTCCTTTCTGGCTCTTGCCTCCGCCTCTCTCTCTCATCCTCTTTGTCCTCAGCTCCTCCTGCTTTCT TGGGTCCCACCAGTGTCACTTTTCTGCCGTTTTCTTTCCTGTTCTCCTCTGCTTCATTCTCGTCCAGCCATTGCTCCCCTCTCCCTGCCA CCCTTCCCCAGTTCACCAAACCTTACATGTTGCAAAAGAGAAAAAAGGAAAAAAAATCAAAACACAAAAAAGCCAAAACGAAAACAAATC TCGAGTGTGTTGCCAAGTGCTGCGTCCTCCTGGTGGCCTCTGTGTGTGTCCCTGTGGCCCGCAGCCTGCCCGCCTGCCCCGCCCATCTGC CGTGTGTCTTGCCCGCCTGCCCCGCCCGTCTGCCGTCTGTCTTGCCCGCCTGCCCGCCTGCCCCTCCTGCCGACCACACGGAGTTCAGTG CCTGGGTGTTTGGTGATGGTTATTGACGACAATGTGTAGCGCATGATTGTTTTTATACCAAGAACATTTCTAATAAAAATAAACACATGG >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374181_chr6_34008525_-_2976nt GGAGTATAGGGCTTGAACTGAGAGCCTGGCCTCCCAGAAGGTTTTAATAGACCTACGGCACAGAAATTGACACAGCCCGGAAAAGGCCCA CAAAGAGAAGCCCAACCAGCCAGCCCCCAGGCCGCCCCGCCAGGGACCCACCAATGAGGCACAGATGGCAGCCGCTGCCGCCCTAGCCCG GCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTGAGAAAGGAACTTCAAGCCGAAGCCAC CGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCTGCCCACCTGGCTGTGCCTGGCGTGTA CTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAGGCCATTCTCTTGACCGTGAGCGAATT GGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCATGGGCCACGCGCTGCACGCCATGCAC CGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGCTGCTTAAGTACATCCGAAACGTCAAC TTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATGACATCTACCAATACCAGCTGCGCAAC GATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGATGCACTGGCCGGGGAGCGGGCAGCAG CTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCATGCCTTGCTGCTGGCACTGCGAGCCT TGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGCCCACAGAGAACCGCACGGGCTGCCGG CCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCGTGGTGGGCATCGCTGCCACGTTGTTC GTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGAGCTACGTGCTGCTGGCAGGCATCTTC CTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCCGAATCTTCCTGGGACTAGGGATGAGC ATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGCGCTCGGTCAGTGCCCCACGCTTCATC AGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTGTGTGGTTTGTGGTGGACCCCTCCCAC TCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGTGTGACATCTCGGACCTGTCGCTCATC TGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCGGCGTGCCCGAGACCTTCAATGAGGCC AAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCTTTGGCACCTCGCAGTCGGCCGACAAG CTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAATGCTCTACATGCCCAAAGTCTACATC ATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGGCGGCCACCATGTCCAACAAGTTCACG CAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCCCAGCGCTGGCCACCAAACAGACTTAC GTCACTTACACCAACCATGCAATCTAGCGAGTCCATGGAGCTGAGCAGCAGGAGGAGGAGCCGTGACCCTGTGGAAGGTGCGTCGGGCCA GGGCCACACCCAAGGGCCCAGCTGTCTTGCCTGCCCGTGGGCACCCACGGACGTGGCTTGGTGCTGAGGATAGCAGAGCCCCCAGCCATC ACTGCTGGCAGCCTGGGCAAACCGGGTGAGCAACAGGAGGACGAGGGGCCGGGGCGGTGCCAGGCTACCACAAGAACCTGCGTCTTGGAC CATTGCCCCTCCCGGCCCCAAACCACAGGGGCTCAGGTCGTGTGGGCCCCAGTGCTAGATCTCTCCCTCCCTTCGTCTCTGTCTGTGCTG TTGGCGACCCCTCTGTCTGTCTCCAGCCCTGTCTTTCTGTTCTCTTATCTCTTTGTTTCACCTTTTCCCTCTCTGGCGTCCCCGGCTGCT TGTACTCTTGGCCTTTTCTGTGTCTCCTTTCTGGCTCTTGCCTCCGCCTCTCTCTCTCATCCTCTTTGTCCTCAGCTCCTCCTGCTTTCT TGGGTCCCACCAGTGTCACTTTTCTGCCGTTTTCTTTCCTGTTCTCCTCTGCTTCATTCTCGTCCAGCCATTGCTCCCCTCTCCCTGCCA CCCTTCCCCAGTTCACCAAACCTTACATGTTGCAAAAGAGAAAAAAGGAAAAAAAATCAAAACACAAAAAAGCCAAAACGAAAACAAATC TCGAGTGTGTTGCCAAGTGCTGCGTCCTCCTGGTGGCCTCTGTGTGTGTCCCTGTGGCCCGCAGCCTGCCCGCCTGCCCCGCCCATCTGC CGTGTGTCTTGCCCGCCTGCCCCGCCCGTCTGCCGTCTGTCTTGCCCGCCTGCCCGCCTGCCCCTCCTGCCGACCACACGGAGTTCAGTG CCTGGGTGTTTGGTGATGGTTATTGACGACAATGTGTAGCGCATGATTGTTTTTATACCAAGAACATTTCTAATAAAAATAAACACATGG >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000374177_chr6_34008525_-_2974nt GGAGTATAGGGCTTGAACTGAGAGCCTGGCCTCCCAGAAGGTTTTAATAGACCTACGGCACAGAAATTGACACAGCCCGGAAAAGGCCCA CAAAGAGAAGCCCAACCAGCCAGCCCCCAGGCCGCCCCGCCAGGGACCCACCAATGAGGCACAGATGGCAGCCGCTGCCGCCCTAGCCCG GCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTGAGAAAGGAACTTCAAGCCGAAGCCAC CGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCTGCCCACCTGGCTGTGCCTGGCGTGTA CTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAGGCCATTCTCTTGACCGTGAGCGAATT GGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCATGGGCCACGCGCTGCACGCCATGCAC CGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGCTGCTTAAGTACATCCGAAACGTCAAC TTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATGACATCTACCAATACCAGCTGCGCAAC GATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGATGCACTGGCCGGGGAGCGGGCAGCAG CTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCATGCCTTGCTGCTGGCACTGCGAGCCT TGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGCCCACAGAGAACCGCACGGGCTGCCGG CCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCGTGGTGGGCATCGCTGCCACGTTGTTC GTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGAGCTACGTGCTGCTGGCAGGCATCTTC CTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCCGAATCTTCCTGGGACTAGGGATGAGC ATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGCGCTCGGTCAGTGCCCCACGCTTCATC AGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTGTGTGGTTTGTGGTGGACCCCTCCCAC TCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGTGTGACATCTCGGACCTGTCGCTCATC TGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCGGCGTGCCCGAGACCTTCAATGAGGCC AAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCTTTGGCACCTCGCAGTCGGCCGACAAG CTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAATGCTCTACATGCCCAAAGTCTACATC ATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGGCGGCCACCATGTCCAACAAGTTCACG CAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCCCAGCGCTGGCCACCAAACAGACTTAC GTCACTTACACCAACCATGCAATCTAGCGAGTCCATGGAGCTGAGCAGCAGGAGGAGGAGCCGTGACCCTGTGGAAGGTGCGTCGGGCCA GGGCCACACCCAAGGGCCCAGCTGTCTTGCCTGCCCGTGGGCACCCACGGACGTGGCTTGGTGCTGAGGATAGCAGAGCCCCCAGCCATC ACTGCTGGCAGCCTGGGCAAACCGGGTGAGCAACAGGAGGACGAGGGGCCGGGGCGGTGCCAGGCTACCACAAGAACCTGCGTCTTGGAC CATTGCCCCTCCCGGCCCCAAACCACAGGGGCTCAGGTCGTGTGGGCCCCAGTGCTAGATCTCTCCCTCCCTTCGTCTCTGTCTGTGCTG TTGGCGACCCCTCTGTCTGTCTCCAGCCCTGTCTTTCTGTTCTCTTATCTCTTTGTTTCACCTTTTCCCTCTCTGGCGTCCCCGGCTGCT TGTACTCTTGGCCTTTTCTGTGTCTCCTTTCTGGCTCTTGCCTCCGCCTCTCTCTCTCATCCTCTTTGTCCTCAGCTCCTCCTGCTTTCT TGGGTCCCACCAGTGTCACTTTTCTGCCGTTTTCTTTCCTGTTCTCCTCTGCTTCATTCTCGTCCAGCCATTGCTCCCCTCTCCCTGCCA CCCTTCCCCAGTTCACCAAACCTTACATGTTGCAAAAGAGAAAAAAGGAAAAAAAATCAAAACACAAAAAAGCCAAAACGAAAACAAATC TCGAGTGTGTTGCCAAGTGCTGCGTCCTCCTGGTGGCCTCTGTGTGTGTCCCTGTGGCCCGCAGCCTGCCCGCCTGCCCCGCCCATCTGC CGTGTGTCTTGCCCGCCTGCCCCGCCCGTCTGCCGTCTGTCTTGCCCGCCTGCCCGCCTGCCCCTCCTGCCGACCACACGGAGTTCAGTG CCTGGGTGTTTGGTGATGGTTATTGACGACAATGTGTAGCGCATGATTGTTTTTATACCAAGAACATTTCTAATAAAAATAAACACATGG >In-frame_UBXN6_ENST00000394765_chr19_4452361_-_GRM4_ENST00000544773_chr6_34008525_-_2395nt GGAGTATAGGGCTTGAACTGAGAGCCTGGCCTCCCAGAAGGTTTTAATAGACCTACGGCACAGAAATTGACACAGCCCGGAAAAGGCCCA CAAAGAGAAGCCCAACCAGCCAGCCCCCAGGCCGCCCCGCCAGGGACCCACCAATGAGGCACAGATGGCAGCCGCTGCCGCCCTAGCCCG GCTGGAGCAGAAGCAGTCCCGGGCCTGGGGCCCCACATCGCAGGACACCATCCGAAACCAGGTGAGAAAGGAACTTCAAGCCGAAGCCAC CGTCAGCGGGAGCCCCGAGGCCCCAGGGACCAACGTGGTATCTGAGCCCAGAGAGGAAGGCTCTGCCCACCTGGCTGTGCCTGGCGTGTA CTTCACCTGTCCGCTCACTGGGGCCACCCTGAGGAAGGACCAGCGGGACGCCTGCATCAAGGAGGCCATTCTCTTGACCGTGAGCGAATT GGGCAGGATTCAGCTTATGAGCAGGAGGGGAAGGTGCAGTTTGTGATCGATGCCGTGTACGCCATGGGCCACGCGCTGCACGCCATGCAC CGTGACCTGTGTCCCGGCCGCGTGGGGCTCTGCCCGCGCATGGACCCTGTAGATGGCACCCAGCTGCTTAAGTACATCCGAAACGTCAAC TTCTCAGGCATCGCAGGGAACCCTGTGACCTTCAATGAGAATGGAGATGCGCCTGGGCGCTATGACATCTACCAATACCAGCTGCGCAAC GATTCTGCCGAGTACAAGGTCATTGGCTCCTGGACTGACCACCTGCACCTTAGAATAGAGCGGATGCACTGGCCGGGGAGCGGGCAGCAG CTGCCCCGCTCCATCTGCAGCCTGCCCTGCCAACCGGGTGAGCGGAAGAAGACAGTGAAGGGCATGCCTTGCTGCTGGCACTGCGAGCCT TGCACAGGGTACCAGTACCAGGTGGACCGCTACACCTGTAAGACGTGTCCCTATGACATGCGGCCCACAGAGAACCGCACGGGCTGCCGG CCCATCCCCATCATCAAGCTTGAGTGGGGCTCGCCCTGGGCCGTGCTGCCCCTCTTCCTGGCCGTGGTGGGCATCGCTGCCACGTTGTTC GTGGTGATCACCTTTGTGCGCTACAACGACACGCCCATCGTCAAGGCCTCGGGCCGTGAACTGAGCTACGTGCTGCTGGCAGGCATCTTC CTGTGCTATGCCACCACCTTCCTCATGATCGCTGAGCCCGACCTTGGCACCTGCTCGCTGCGCCGAATCTTCCTGGGACTAGGGATGAGC ATCAGCTATGCAGCCCTGCTCACCAAGACCAACCGCATCTACCGCATCTTCGAGCAGGGCAAGCGCTCGGTCAGTGCCCCACGCTTCATC AGCCCCGCCTCACAGCTGGCCATCACCTTCAGCCTCATCTCGCTGCAGCTGCTGGGCATCTGTGTGTGGTTTGTGGTGGACCCCTCCCAC TCGGTGGTGGACTTCCAGGACCAGCGGACACTCGACCCCCGCTTCGCCAGGGGTGTGCTCAAGTGTGACATCTCGGACCTGTCGCTCATC TGCCTGCTGGGCTACAGCATGCTGCTCATGGTCACGTGCACCGTGTATGCCATCAAGACACGCGGCGTGCCCGAGACCTTCAATGAGGCC AAGCCCATTGGCTTCACCATGTACACCACTTGCATCGTCTGGCTGGCCTTCATCCCCATCTTCTTTGGCACCTCGCAGTCGGCCGACAAG CTGTACATCCAGACGACGACGCTGACGGTCTCGGTGAGTCTGAGCGCCTCGGTGTCCCTGGGAATGCTCTACATGCCCAAAGTCTACATC ATCCTCTTCCACCCGGAGCAGAACGTGCCCAAGCGCAAGCGCAGCCTCAAAGCCGTCGTTACGGCGGCCACCATGTCCAACAAGTTCACG CAGAAGGGCAACTTCCGGCCCAACGGAGAGGCCAAGTCTGAGCTCTGCGAGAACCTTGAGGCCCCAGCGCTGGCCACCAAACAGACTTAC GTCACTTACACCAACCATGCAATCTAGCGAGTCCATGGAGCTGAGCAGCAGGAGGAGGAGCCGTGACCCTGTGGAAGGTGCGTCGGGCCA GGGCCACACCCAAGGGCCCAGCTGTCTTGCCTGCCCGTGGGCACCCACGGACGTGGCTTGGTGCTGAGGATAGCAGAGCCCCCAGCCATC ACTGCTGGCAGCCTGGGCAAACCGGGTGAGCAACAGGAGGACGAGGGGCCGGGGCGGTGCCAGGCTACCACAAGAACCTGCGTCTTGGAC CATTGCCCCTCCCGGCCCCAAACCACAGGGGCTCAGGTCGTGTGGGCCCCAGTGCTAGATCTCTCCCTCCCTTCGTCTCTGTCTGTGCTG |
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FusionGenePPI for UBXN6_GRM4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBXN6 | VCP, ALPP, VCPIP1, GSK3B, ELAVL1, DERL1, UFD1L, PSMD2, LMAN1, LIMA1, SEPT9, DST, TUBA1C, RUVBL2, ASPSCR1, FAF2, UGGT1, HSPA1A, EEF1A2, TUBB6, RUVBL1, RPS3, PRKDC, CCT8, IRS4, NPLOC4, CANX, FLOT1, HNRNPU, MCFD2, COPA, APP, TRIM25, VPS39, ZC3H7B, XPO6, CAV1, VCPKMT, BAG3, MAGEA4, TRIM39, MOV10, NXF1, POR, UBXN2A, FAM104A, NSFL1C, ARAF, ACTBL2, UBXN10, UBXN4, FAF1, NLGN3, SMURF1, MCL1 | GRM4 | EGFR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBXN6_GRM4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | GRM4 | Q14833 | DB00142 | Glutamic Acid | Metabotropic glutamate receptor 4 | small molecule | approved|nutraceutical |
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RelatedDiseases for UBXN6_GRM4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | GRM4 | C0036341 | Schizophrenia | 3 | PSYGENET |
| Tgene | GRM4 | C0005586 | Bipolar Disorder | 2 | PSYGENET |
| Tgene | GRM4 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Tgene | GRM4 | C0014556 | Epilepsy, Temporal Lobe | 1 | CTD_human |
| Tgene | GRM4 | C0027746 | Nerve Degeneration | 1 | CTD_human |
| Tgene | GRM4 | C0029463 | Osteosarcoma | 1 | CTD_human |
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