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Fusion gene ID: 40593 |
FusionGeneSummary for UBR2_XPO5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBR2_XPO5 | Fusion gene ID: 40593 | Hgene | Tgene | Gene symbol | UBR2 | XPO5 | Gene ID | 23304 | 57510 |
| Gene name | ubiquitin protein ligase E3 component n-recognin 2 | exportin 5 | |
| Synonyms | C6orf133|bA49A4.1|dJ242G1.1|dJ392M17.3 | exp5 | |
| Cytomap | 6p21.1 | 6p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase UBR2RING-type E3 ubiquitin transferase UBR2ubiquitin-protein ligase E3-alpha-2ubiquitin-protein ligase E3-alpha-II | exportin-5ran-binding protein 21 | |
| Modification date | 20180529 | 20180527 | |
| UniProtAcc | Q8IWV8 | Q9HAV4 | |
| Ensembl transtripts involved in fusion gene | ENST00000372899, ENST00000372901, ENST00000372883, ENST00000372903, | ENST00000265351, ENST00000424378, | |
| Fusion gene scores | * DoF score | 9 X 9 X 6=486 | 2 X 2 X 2=8 |
| # samples | 9 | 2 | |
| ** MAII score | log2(9/486*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: UBR2 [Title/Abstract] AND XPO5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBR2 | GO:0071233 | cellular response to leucine | 20298436 |
| Tgene | XPO5 | GO:0006611 | protein export from nucleus | 11777942|24209753 |
| Tgene | XPO5 | GO:0035281 | pre-miRNA export from nucleus | 15613540 |
| Tgene | XPO5 | GO:1900370 | positive regulation of RNA interference | 15613540 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-KK-A59X-01A | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000372899 | ENST00000265351 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| 5CDS-intron | ENST00000372899 | ENST00000424378 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| In-frame | ENST00000372901 | ENST00000265351 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| 5CDS-intron | ENST00000372901 | ENST00000424378 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| 3UTR-3CDS | ENST00000372883 | ENST00000265351 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| 3UTR-intron | ENST00000372883 | ENST00000424378 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| intron-3CDS | ENST00000372903 | ENST00000265351 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
| intron-intron | ENST00000372903 | ENST00000424378 | UBR2 | chr6 | 42650849 | + | XPO5 | chr6 | 43501744 | - |
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FusionProtFeatures for UBR2_XPO5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBR2 | XPO5 |
| E3 ubiquitin-protein ligase which is a component of theN-end rule pathway. Recognizes and binds to proteins bearingspecific N-terminal residues that are destabilizing according tothe N-end rule, leading to their ubiquitination and subsequentdegradation. Plays a critical role in chromatin inactivation andchromosome-wide transcriptional silencing during meiosis viaubiquitination of histone H2A. Binds leucine and is a negativeregulator of the leucine-mTOR signaling pathway, therebycontrolling cell growth. Required for spermatogenesis, promotes,with Tex19.1, SPO11-dependent recombination foci to accumulate anddrive robust homologous chromosome synapsis (By similarity).Polyubiquitinates LINE-1 retrotransposon encoded, LIRE1, whichinduces degradation, inhibiting LINE-1 retranstoposon mobilization(By similarity). {ECO:0000250|UniProtKB:Q6WKZ8,ECO:0000269|PubMed:15548684, ECO:0000269|PubMed:20298436,ECO:0000269|PubMed:20835242}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372883 | + | 34 | 38 | 1019_1054 | 1054 | 662 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372899 | + | 43 | 47 | 1019_1054 | 1591 | 1756 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372901 | + | 43 | 47 | 1019_1054 | 1591 | 1756 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372883 | + | 34 | 38 | 1108_1214 | 1054 | 662 | Zinc finger | Note=RING-type%3B atypical |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372883 | + | 34 | 38 | 97_168 | 1054 | 662 | Zinc finger | UBR-type |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372899 | + | 43 | 47 | 1108_1214 | 1591 | 1756 | Zinc finger | Note=RING-type%3B atypical |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372899 | + | 43 | 47 | 97_168 | 1591 | 1756 | Zinc finger | UBR-type |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372901 | + | 43 | 47 | 1108_1214 | 1591 | 1756 | Zinc finger | Note=RING-type%3B atypical |
| Hgene | UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372901 | + | 43 | 47 | 97_168 | 1591 | 1756 | Zinc finger | UBR-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372903 | + | 1 | 12 | 1019_1054 | -86 | 440 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372903 | + | 1 | 12 | 1108_1214 | -86 | 440 | Zinc finger | Note=RING-type%3B atypical |
| Hgene | >UBR2 | chr6:42650849 | chr6:43501744 | ENST00000372903 | + | 1 | 12 | 97_168 | -86 | 440 | Zinc finger | UBR-type |
| Tgene | XPO5 | chr6:42650849 | chr6:43501744 | ENST00000265351 | - | 19 | 32 | 641_642 | 780 | 1205 | Region | Pre-miRNA binding |
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FusionGeneSequence for UBR2_XPO5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBR2_ENST00000372899_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_2016aa MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLE QANKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRR SVRYGDFQYCEQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQFFTAPTLARMLITEENLMSIIIKTFMDHLR HRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIRYCVSQEKVSIHLPVSRLLAGLHVLLSKSEV AYKFPELLPLSELSPPMLIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAHSELVKSLPEDENKETGM ESVIEAVAHFKKPGLTGRGMYELKPECAKEFNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIR WILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSKFIQDPEKYDPLFMHPDLSCGTHTSSCGH IMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPIMCWGSCAYTIQSIERILSDE DKPLFGPLPCRLDDCLRSLTRFAAAHWTVASVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPSGWHLWRSVRAGIMPFLKCSALFFHYLNGVP SPPDIQVPGTSHFEHLCSYLSLPNNLICLFQENSEIMNSLIESWCRNSEVKRYLEGERDAIRTHNTLYAPEMLAKMAEPFTKALDMLDAE KSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPL VLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVSKKGADHSSAP PADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKG LQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRRKDQFKRLIAGCIGKPLGEQFRKE >In-frame_UBR2_ENST00000372901_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_2016aa MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLE QANKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRR SVRYGDFQYCEQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQIFTVPSLARMLITEENLMSIIIKTFMDHLR HRDAQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIRYCVSQEKVSIHLPVSRLLAGLHVLLSKSEV AYKFPELLPLSELSPPMLIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKREIIHQLSIKPMAHSELVKSLPEDENKETGM ESVIEAVAHFKKPGLTGRGMYELKPECAKEFNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIR WILKTFNAVKKMRESSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNRSKFIQDPEKYDPLFMHPDLSCGTHTSSCGH IMHAHCWQRYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPIMCWGSCAYTIQSIERILSDE DKPLFGPLPCRLDDCLRSLTRFAAAHWTVASVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPSGWHLWRSVRAGIMPFLKCSALFFHYLNGVP SPPDIQVPGTSHFEHLCSYLSLPNNLICLFQENSEIMNSLIESWCRNSEVKRYLEGERDAIRTHNTLYAPEMLAKMAEPFTKALDMLDAE KSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPL VLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVSKKGADHSSAP PADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKG LQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRRKDQFKRLIAGCIGKPLGEQFRKE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBR2_ENST00000372899_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_6048nt ATGGCGTCGGAGCTAGAGCCAGAGGTGCAGGCCATCGACCGGAGCTTGCTGGAATGTTCGGCCGAGGAGATTGCGGGGAAATGGCTGCAA GCAACTGACCTCACTAGAGAAGTGTACCAGCATTTAGCCCACTATGTACCCAAAATCTACTGCAGGGGTCCCAACCCTTTTCCACAGAAA GAAGACATGCTGGCACAGCATGTTTTGTTGGGACCAATGGAATGGTACCTTTGTGGTGAAGATCCTGCATTTGGATTTCCAAAACTTGAG CAAGCAAACAAACCTTCTCATCTTTGTGGTCGTGTTTTTAAAGTAGGAGAGCCTACATATTCTTGCAGAGACTGTGCAGTTGATCCAACT TGTGTTTTGTGCATGGAGTGCTTTTTGGGAAGTATTCACAGAGATCATCGATATAGGATGACAACATCAGGAGGTGGAGGTTTCTGTGAC TGTGGTGATACTGAAGCCTGGAAAGAGGGTCCTTACTGTCAAAAACATGAACTTAACACCTCTGAAATTGAGGAAGAAGAGGATCCTCTT GTTCATTTATCAGAAGATGTGATAGCAAGAACTTATAACATTTTTGCTATTACGTTTCGGTATGCAGTAGAAATATTAACCTGGGAAAAA GAAAGTGAATTGCCAGCAGATTTAGAGATGGTAGAGAAGAGTGACACCTACTATTGCATGCTGTTTAATGATGAGGTTCACACCTATGAA CAAGTTATTTATACTCTTCAGAAAGCTGTTAACTGTACACAAAAAGAAGCTATTGGTTTTGCAACTACAGTAGATCGAGATGGGCGTAGG TCTGTTCGATATGGAGATTTTCAGTATTGTGAGCAAGCAAAATCAGTAATTGTGAGAAATACCAGTAGACAGACAAAGCCACTCAAAGTT CAAGTTATGCATTCGTCTATTGTCGCACATCAGAATTTTGGTTTGAAACTTTTGTCTTGGCTGGGAAGTATTATTGGATATTCAGATGGC CTTCGCCGGATTTTATGTCAAGTTGGTTTACAAGAAGGGCCAGATGGTGAAAACTCTTCTCTAGTGGACAGACTGATGCTTAGTGATTCC AAATTATGGAAAGGTGCTAGGAGTGTATATCATCAGTTGTTCATGAGCAGTCTGCTTATGGATTTGAAATACAAGAAACTATTTGCTGTT CGATTTGCAAAAAATTACCAGCAGTTGCAGAGAGATTTTATGGAGGATGATCACGAGCGAGCAGTGTCGGTGACTGCTCTATCTGTCCAG TTCTTCACCGCACCTACTCTGGCTCGAATGCTCATCACAGAAGAAAACTTAATGAGCATTATCATTAAGACTTTTATGGATCATTTGAGA CATCGAGATGCCCAGGGCAGATTTCAGTTTGAACGATACACTGCTTTACAAGCCTTCAAATTTAGGAGAGTACAGAGCCTTATTTTAGAT CTCAAGTATGTGTTAATTAGCAAACCAACTGAATGGTCAGATGAGCTGAGGCAGAAGTTCCTAGAAGGGTTTGATGCCTTTTTGGAATTA CTAAAATGTATGCAGGGAATGGATCCAATTACACGTCAAGTAGGACAACATATTGAAATGGAACCAGAGTGGGAAGCAGCCTTCACACTA CAAATGAAATTAACACATGTCATTTCAATGATGCAGGACTGGTGTGCTTCAGATGAAAAAGTGTTAATCGAAGCTTACAAGAAATGTCTC GCTGTACTGATGCAGTGTCATGGTGGTTATACTGATGGTGAACAGCCAATCACACTAAGCATTTGTGGACATTCAGTGGAAACTATCAGA TACTGTGTTTCCCAAGAAAAAGTTAGCATTCACCTCCCAGTTTCTCGCTTACTTGCAGGTTTACATGTATTATTAAGCAAAAGTGAAGTG GCATATAAATTTCCAGAGCTCCTACCTCTAAGTGAACTTAGCCCACCCATGTTGATAGAACACCCTCTTAGATGTCTTGTTCTGTGTGCC CAAGTACATGCCGGAATGTGGAGAAGAAATGGGTTCTCTCTAGTAAACCAGATTTATTACTACCATAATGTGAAATGCAGACGTGAGATG TTTGACAAGGATGTAGTAATGCTTCAGACAGGTGTCTCCATGATGGATCCAAATCATTTCCTGATGATCATGCTCAGCCGCTTTGAACTT TATCAGATTTTCAGTACTCCAGACTATGGAAAAAGATTTAGTTCTGAGATTACCCATAAGGATGTTGTTCAGCAGAACAATACTCTAATA GAAGAAATGCTATACCTCATTATAATGCTTGTTGGAGAGAGATTTAGTCCTGGAGTTGGACAGGTAAATGCTACAGATGAAATCAAGCGA GAGATTATCCATCAGTTGAGTATCAAGCCTATGGCTCATAGTGAATTGGTAAAGTCTTTACCTGAAGATGAGAACAAGGAGACTGGCATG GAGAGTGTAATCGAAGCAGTTGCCCATTTCAAGAAACCTGGATTAACAGGACGAGGCATGTATGAACTGAAACCAGAATGTGCCAAAGAG TTCAACTTGTATTTCTATCACTTTTCAAGGGCAGAACAGTCCAAGGCAGAAGAAGCGCAACGGAAATTGAAAAGACAAAATAGAGAAGAT ACAGCACTCCCACCTCCGGTGTTGCCTCCATTCTGCCCTCTGTTTGCAAGCCTGGTTAACATTTTGCAGTCAGATGTCATGTTGTGCATC ATGGGAACAATTCTGCAATGGGCTGTGGAACATAATGGATATGCCTGGTCAGAGTCCATGCTGCAAAGGGTGTTACATTTAATTGGCATG GCACTACAAGAAGAAAAACAACATTTAGAGAATGTCACGGAAGAGCATGTAGTAACATTTACCTTCACTCAGAAGATATCAAAACCTGGT GAAGCGCCAAAAAATTCTCCTAGCATACTAGCTATGCTGGAAACACTACAAAATGCTCCCTACCTAGAAGTCCACAAAGACATGATTCGG TGGATATTGAAGACTTTTAATGCTGTTAAAAAGATGAGGGAGAGTTCACCTACCAGTCCCGTGGCAGAGACAGAAGGAACCATAATGGAA GAGAGTTCAAGGGACAAAGACAAAGCTGAGAGGAAGAGAAAAGCAGAGATTGCCAGACTGCGCAGAGAAAAGATCATGGCTCAGATGTCT GAAATGCAGCGGCATTTTATTGATGAAAACAAAGAACTCTTTCAGCAGACATTAGAACTGGATGCCTCAACCTCTGCTGTTCTTGATCAT AGCCCTGTGGCTTCAGATATGACACTTACAGCACTGGGCCCCGCACAAACTCAGGTTCCTGAACAAAGACAATTCGTTACATGTATATTG TGTCAAGAGGAGCAAGAAGTTAAAGTGGAAAGCAGGGCAATGGTCTTGGCAGCATTTGTTCAGAGATCAACTGTATTATCAAAAAACAGA AGTAAATTTATTCAAGATCCAGAAAAATATGATCCATTATTCATGCACCCTGATCTGTCTTGTGGAACACACACTAGTAGCTGTGGGCAC ATTATGCATGCCCATTGTTGGCAAAGGTATTTTGATTCCGTTCAAGCTAAAGAACAGCGAAGGCAACAGAGATTACGCTTACATACGAGC TATGATGTAGAAAACGGAGAATTCCTTTGCCCCCTTTGTGAATGCTTGAGTAATACTGTTATTCCTCTGCTGCTTCCTCCAAGAAATATT TTTAACAACAGGTTAAATTTTTCAGACCAACCAAATCTGACTCAGTGGATTAGAACAATATCTCAGCAAATAAAAGCATTACAGTTTCTT AGGAAAGAAGAAAGTACTCCTAATAATGCCTCTACAAAGAATTCAGAAAATGTGGATGAATTACAGCTCCCTGAAGGGTTCAGGCCTGAT TTTCGTCCTAAGATCCCTTATTCTGAGAGCATAAAAGAAATGCTAACGACATTTGGAACTGCTACCTACAAGGTGGGACTAAAGGTTCAT CCCAATGAAGAGGATCCTCGTGTTCCCATAATGTGTTGGGGTAGCTGCGCGTACACCATCCAAAGCATAGAAAGAATTTTGAGTGATGAA GATAAACCATTGTTTGGTCCTTTACCTTGCAGACTGGATGACTGTCTTAGGTCATTGACGAGATTTGCCGCAGCACACTGGACAGTGGCA TCAGTTTCAGTGGTGCAAGGACATTTTTGTAAACTTTTTGCATCACTGGTGCCTAATGACAGCCATGAGGAACTTCCATGCATATTAGAT ATTGACATGTTTCATTTATTGGTGGGCTTGGTGCTTGCATTTCCTGCGTTGCAGTGTCAGGATTTTTCAGGGATCAGCCTTGGCACTGGA GACCTTCACATTTTCCATCTGGTTACTATGGCACACATCATACAGATCTTACTTACCTCATGTACAGAAGAGAATGGCATGGATCAAGAA AATCCCCCTTGTGAAGAAGAATCAGCAGTTCTTGCTTTGTATAAAACACTTCACCAGTATACGGGAAGTGCCTTGAAAGAAATACCATCC GGCTGGCATCTGTGGAGGAGTGTCAGAGCTGGAATCATGCCTTTCCTGAAGTGTTCTGCTTTATTTTTTCATTACTTAAATGGAGTTCCT TCCCCACCCGACATTCAAGTTCCTGGAACAAGCCATTTTGAACATTTATGTAGCTATCTTTCCCTACCAAACAACCTCATTTGCCTTTTT CAAGAAAATAGTGAGATAATGAATTCACTGATTGAAAGTTGGTGCCGTAACAGTGAAGTTAAAAGATATCTAGAAGGTGAAAGAGATGCT ATAAGAACCCACAATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCACCAAGGCTCTGGATATGCTTGACGCGGAA AAATCTGCTATATTAGGATTACCTCAACCTCTCTTGGAACTCAATGACTCTCCTGTCTTCAAAACCGTCTTGGAAAGAATGCAGCGTTTC TTCTCTACCCTCTATGAAAACTGTTTTCATATCCTAGGGAAGGCAGGCCCTTCCATGCAGCAAGACTTCTATACTGTGGAGGACCTTGCT ACCCAGCTTCTCAGCTCAGCCTTTGTCAACTTGAACAATATTCCTGACTACCGACTCAGACCCATGCTTCGTGTCTTTGTAAAGCCTCTG GTGCTCTTCTGTCCCCCAGAGCACTATGAAGCCCTGGTATCCCCCATCCTCGGACCTCTTTTCACCTACCTCCATATGAGGCTTTCTCAG AAATGGCAAGTTATCAACCAAAGGAGCCTGCTGTGTGGAGAAGATGAGGCTGCAGATGAAAACCCAGAGTCTCAAGAGATGCTGGAGGAG CAACTGGTGAGGATGTTAACCCGAGAAGTCATGGACCTAATCACGGTTTGCTGTGTTTCAAAGAAGGGTGCTGACCACAGTAGTGCTCCC CCAGCAGATGGAGACGATGAAGAAATGATGGCCACAGAGGTCACCCCCTCAGCTATGGCAGAGCTTACAGACCTGGGCAAATGTCTGATG AAGCATGAGGATGTTTGTACAGCGCTATTAATTACAGCCTTCAATTCCCTGGCCTGGAAAGATACTCTGTCCTGCCAGAGGACAACCTCA CAGCTCTGCTGGCCTCTCCTCAAACAAGTGCTGTCAGGGACACTGCTCGCAGATGCAGTTACGTGGCTTTTCACCAGTGTGCTGAAAGGC TTACAGATGCACGGGCAGCACGACGGGTGCATGGCTTCCCTGGTCCATCTGGCCTTCCAGATATACGAGGCACTGCGCCCCAGGTACCTG GAGATAAGAGCTGTAATGGAGCAAATCCCTGAAATACAGAAGGACTCACTGGACCAGTTTGACTGCAAGCTTTTAAACCCCTCCCTGCAG AAAGTGGCTGACAAGCGCCGAAAGGACCAATTCAAACGCCTCATTGCTGGTTGCATTGGGAAACCCTTGGGAGAGCAGTTCCGAAAAGAA GTTCACATTAAGAATCTTCCCTCACTTTTCAAAAAAACAAAGCCAATGCTGGAGACGGAGGTGCTGGACAATGATGGGGGTGGCCTGGCC >In-frame_UBR2_ENST00000372901_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_6048nt ATGGCGTCGGAGCTAGAGCCAGAGGTGCAGGCCATCGACCGGAGCTTGCTGGAATGTTCGGCCGAGGAGATTGCGGGGAAATGGCTGCAA GCAACTGACCTCACTAGAGAAGTGTACCAGCATTTAGCCCACTATGTACCCAAAATCTACTGCAGGGGTCCCAACCCTTTTCCACAGAAA GAAGACATGCTGGCACAGCATGTTTTGTTGGGACCAATGGAATGGTACCTTTGTGGTGAAGATCCTGCATTTGGATTTCCAAAACTTGAG CAAGCAAACAAACCTTCTCATCTTTGTGGTCGTGTTTTTAAAGTAGGAGAGCCTACATATTCTTGCAGAGACTGTGCAGTTGATCCAACT TGTGTTTTGTGCATGGAGTGCTTTTTGGGAAGTATTCACAGAGATCATCGATATAGGATGACAACATCAGGAGGTGGAGGTTTCTGTGAC TGTGGTGATACTGAAGCCTGGAAAGAGGGTCCTTACTGTCAAAAACATGAACTTAACACCTCTGAAATTGAGGAAGAAGAGGATCCTCTT GTTCATTTATCAGAAGATGTGATAGCAAGAACTTATAACATTTTTGCTATTACGTTTCGGTATGCAGTAGAAATATTAACCTGGGAAAAA GAAAGTGAATTGCCAGCAGATTTAGAGATGGTAGAGAAGAGTGACACCTACTATTGCATGCTGTTTAATGATGAGGTTCACACCTATGAA CAAGTTATTTATACTCTTCAGAAAGCTGTTAACTGTACACAAAAAGAAGCTATTGGTTTTGCAACTACAGTAGATCGAGATGGGCGTAGG TCTGTTCGATATGGAGATTTTCAGTATTGTGAGCAAGCAAAATCAGTAATTGTGAGAAATACCAGTAGACAGACAAAGCCACTCAAAGTT CAAGTTATGCATTCGTCTATTGTCGCACATCAGAATTTTGGTTTGAAACTTTTGTCTTGGCTGGGAAGTATTATTGGATATTCAGATGGC CTTCGCCGGATTTTATGTCAAGTTGGTTTACAAGAAGGGCCAGATGGTGAAAACTCTTCTCTAGTGGACAGACTGATGCTTAGTGATTCC AAATTATGGAAAGGTGCTAGGAGTGTATATCATCAGTTGTTCATGAGCAGTCTGCTTATGGATTTGAAATACAAGAAACTATTTGCTGTT CGATTTGCAAAAAACTATGAGCGTTTGCAGAGTGATTATGTGACAGATGACCACGACAGAGAGTTTTCAGTCGCAGACCTCTCGGTTCAG ATATTCACGGTTCCTTCACTTGCTCGAATGCTCATCACAGAAGAAAACTTAATGAGCATTATCATTAAGACTTTTATGGATCATTTGAGA CATCGAGATGCCCAGGGCAGATTTCAGTTTGAACGATACACTGCTTTACAAGCCTTCAAATTTAGGAGAGTACAGAGCCTTATTTTAGAT CTCAAGTATGTGTTAATTAGCAAACCAACTGAATGGTCAGATGAGCTGAGGCAGAAGTTCCTAGAAGGGTTTGATGCCTTTTTGGAATTA CTAAAATGTATGCAGGGAATGGATCCAATTACACGTCAAGTAGGACAACATATTGAAATGGAACCAGAGTGGGAAGCAGCCTTCACACTA CAAATGAAATTAACACATGTCATTTCAATGATGCAGGACTGGTGTGCTTCAGATGAAAAAGTGTTAATCGAAGCTTACAAGAAATGTCTC GCTGTACTGATGCAGTGTCATGGTGGTTATACTGATGGTGAACAGCCAATCACACTAAGCATTTGTGGACATTCAGTGGAAACTATCAGA TACTGTGTTTCCCAAGAAAAAGTTAGCATTCACCTCCCAGTTTCTCGCTTACTTGCAGGTTTACATGTATTATTAAGCAAAAGTGAAGTG GCATATAAATTTCCAGAGCTCCTACCTCTAAGTGAACTTAGCCCACCCATGTTGATAGAACACCCTCTTAGATGTCTTGTTCTGTGTGCC CAAGTACATGCCGGAATGTGGAGAAGAAATGGGTTCTCTCTAGTAAACCAGATTTATTACTACCATAATGTGAAATGCAGACGTGAGATG TTTGACAAGGATGTAGTAATGCTTCAGACAGGTGTCTCCATGATGGATCCAAATCATTTCCTGATGATCATGCTCAGCCGCTTTGAACTT TATCAGATTTTCAGTACTCCAGACTATGGAAAAAGATTTAGTTCTGAGATTACCCATAAGGATGTTGTTCAGCAGAACAATACTCTAATA GAAGAAATGCTATACCTCATTATAATGCTTGTTGGAGAGAGATTTAGTCCTGGAGTTGGACAGGTAAATGCTACAGATGAAATCAAGCGA GAGATTATCCATCAGTTGAGTATCAAGCCTATGGCTCATAGTGAATTGGTAAAGTCTTTACCTGAAGATGAGAACAAGGAGACTGGCATG GAGAGTGTAATCGAAGCAGTTGCCCATTTCAAGAAACCTGGATTAACAGGACGAGGCATGTATGAACTGAAACCAGAATGTGCCAAAGAG TTCAACTTGTATTTCTATCACTTTTCAAGGGCAGAACAGTCCAAGGCAGAAGAAGCGCAACGGAAATTGAAAAGACAAAATAGAGAAGAT ACAGCACTCCCACCTCCGGTGTTGCCTCCATTCTGCCCTCTGTTTGCAAGCCTGGTTAACATTTTGCAGTCAGATGTCATGTTGTGCATC ATGGGAACAATTCTGCAATGGGCTGTGGAACATAATGGATATGCCTGGTCAGAGTCCATGCTGCAAAGGGTGTTACATTTAATTGGCATG GCACTACAAGAAGAAAAACAACATTTAGAGAATGTCACGGAAGAGCATGTAGTAACATTTACCTTCACTCAGAAGATATCAAAACCTGGT GAAGCGCCAAAAAATTCTCCTAGCATACTAGCTATGCTGGAAACACTACAAAATGCTCCCTACCTAGAAGTCCACAAAGACATGATTCGG TGGATATTGAAGACTTTTAATGCTGTTAAAAAGATGAGGGAGAGTTCACCTACCAGTCCCGTGGCAGAGACAGAAGGAACCATAATGGAA GAGAGTTCAAGGGACAAAGACAAAGCTGAGAGGAAGAGAAAAGCAGAGATTGCCAGACTGCGCAGAGAAAAGATCATGGCTCAGATGTCT GAAATGCAGCGGCATTTTATTGATGAAAACAAAGAACTCTTTCAGCAGACATTAGAACTGGATGCCTCAACCTCTGCTGTTCTTGATCAT AGCCCTGTGGCTTCAGATATGACACTTACAGCACTGGGCCCCGCACAAACTCAGGTTCCTGAACAAAGACAATTCGTTACATGTATATTG TGTCAAGAGGAGCAAGAAGTTAAAGTGGAAAGCAGGGCAATGGTCTTGGCAGCATTTGTTCAGAGATCAACTGTATTATCAAAAAACAGA AGTAAATTTATTCAAGATCCAGAAAAATATGATCCATTATTCATGCACCCTGATCTGTCTTGTGGAACACACACTAGTAGCTGTGGGCAC ATTATGCATGCCCATTGTTGGCAAAGGTATTTTGATTCCGTTCAAGCTAAAGAACAGCGAAGGCAACAGAGATTACGCTTACATACGAGC TATGATGTAGAAAACGGAGAATTCCTTTGCCCCCTTTGTGAATGCTTGAGTAATACTGTTATTCCTCTGCTGCTTCCTCCAAGAAATATT TTTAACAACAGGTTAAATTTTTCAGACCAACCAAATCTGACTCAGTGGATTAGAACAATATCTCAGCAAATAAAAGCATTACAGTTTCTT AGGAAAGAAGAAAGTACTCCTAATAATGCCTCTACAAAGAATTCAGAAAATGTGGATGAATTACAGCTCCCTGAAGGGTTCAGGCCTGAT TTTCGTCCTAAGATCCCTTATTCTGAGAGCATAAAAGAAATGCTAACGACATTTGGAACTGCTACCTACAAGGTGGGACTAAAGGTTCAT CCCAATGAAGAGGATCCTCGTGTTCCCATAATGTGTTGGGGTAGCTGCGCGTACACCATCCAAAGCATAGAAAGAATTTTGAGTGATGAA GATAAACCATTGTTTGGTCCTTTACCTTGCAGACTGGATGACTGTCTTAGGTCATTGACGAGATTTGCCGCAGCACACTGGACAGTGGCA TCAGTTTCAGTGGTGCAAGGACATTTTTGTAAACTTTTTGCATCACTGGTGCCTAATGACAGCCATGAGGAACTTCCATGCATATTAGAT ATTGACATGTTTCATTTATTGGTGGGCTTGGTGCTTGCATTTCCTGCGTTGCAGTGTCAGGATTTTTCAGGGATCAGCCTTGGCACTGGA GACCTTCACATTTTCCATCTGGTTACTATGGCACACATCATACAGATCTTACTTACCTCATGTACAGAAGAGAATGGCATGGATCAAGAA AATCCCCCTTGTGAAGAAGAATCAGCAGTTCTTGCTTTGTATAAAACACTTCACCAGTATACGGGAAGTGCCTTGAAAGAAATACCATCC GGCTGGCATCTGTGGAGGAGTGTCAGAGCTGGAATCATGCCTTTCCTGAAGTGTTCTGCTTTATTTTTTCATTACTTAAATGGAGTTCCT TCCCCACCCGACATTCAAGTTCCTGGAACAAGCCATTTTGAACATTTATGTAGCTATCTTTCCCTACCAAACAACCTCATTTGCCTTTTT CAAGAAAATAGTGAGATAATGAATTCACTGATTGAAAGTTGGTGCCGTAACAGTGAAGTTAAAAGATATCTAGAAGGTGAAAGAGATGCT ATAAGAACCCACAATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCACCAAGGCTCTGGATATGCTTGACGCGGAA AAATCTGCTATATTAGGATTACCTCAACCTCTCTTGGAACTCAATGACTCTCCTGTCTTCAAAACCGTCTTGGAAAGAATGCAGCGTTTC TTCTCTACCCTCTATGAAAACTGTTTTCATATCCTAGGGAAGGCAGGCCCTTCCATGCAGCAAGACTTCTATACTGTGGAGGACCTTGCT ACCCAGCTTCTCAGCTCAGCCTTTGTCAACTTGAACAATATTCCTGACTACCGACTCAGACCCATGCTTCGTGTCTTTGTAAAGCCTCTG GTGCTCTTCTGTCCCCCAGAGCACTATGAAGCCCTGGTATCCCCCATCCTCGGACCTCTTTTCACCTACCTCCATATGAGGCTTTCTCAG AAATGGCAAGTTATCAACCAAAGGAGCCTGCTGTGTGGAGAAGATGAGGCTGCAGATGAAAACCCAGAGTCTCAAGAGATGCTGGAGGAG CAACTGGTGAGGATGTTAACCCGAGAAGTCATGGACCTAATCACGGTTTGCTGTGTTTCAAAGAAGGGTGCTGACCACAGTAGTGCTCCC CCAGCAGATGGAGACGATGAAGAAATGATGGCCACAGAGGTCACCCCCTCAGCTATGGCAGAGCTTACAGACCTGGGCAAATGTCTGATG AAGCATGAGGATGTTTGTACAGCGCTATTAATTACAGCCTTCAATTCCCTGGCCTGGAAAGATACTCTGTCCTGCCAGAGGACAACCTCA CAGCTCTGCTGGCCTCTCCTCAAACAAGTGCTGTCAGGGACACTGCTCGCAGATGCAGTTACGTGGCTTTTCACCAGTGTGCTGAAAGGC TTACAGATGCACGGGCAGCACGACGGGTGCATGGCTTCCCTGGTCCATCTGGCCTTCCAGATATACGAGGCACTGCGCCCCAGGTACCTG GAGATAAGAGCTGTAATGGAGCAAATCCCTGAAATACAGAAGGACTCACTGGACCAGTTTGACTGCAAGCTTTTAAACCCCTCCCTGCAG AAAGTGGCTGACAAGCGCCGAAAGGACCAATTCAAACGCCTCATTGCTGGTTGCATTGGGAAACCCTTGGGAGAGCAGTTCCGAAAAGAA GTTCACATTAAGAATCTTCCCTCACTTTTCAAAAAAACAAAGCCAATGCTGGAGACGGAGGTGCTGGACAATGATGGGGGTGGCCTGGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBR2_ENST00000372899_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_7840nt TTCTGTGTCCTTCCCTGGGTCAGGGACGAGCCAGTGACTTGACTCTTGGGCGCTAAGCTTGGGAGGGAGCGCAGGAGGCCGCTGTCCTTC CTTTCCGGTTCACGTCACCCTTCTCTCCCTCTGTTGCTCCACCTGCAGCCACTTGGACGGCTCCGGGACTGATTGCCTGGGGCAGGGGTG GCAGTCGAGGCCGCCGGGGCCGAGGTGAGGCTGCAGCTCTCCGGGCGGCGGTAGCGCTGGGGAGGAGGAGGAGAGAAGATGGCGTCGGAG CTAGAGCCAGAGGTGCAGGCCATCGACCGGAGCTTGCTGGAATGTTCGGCCGAGGAGATTGCGGGGAAATGGCTGCAAGCAACTGACCTC ACTAGAGAAGTGTACCAGCATTTAGCCCACTATGTACCCAAAATCTACTGCAGGGGTCCCAACCCTTTTCCACAGAAAGAAGACATGCTG GCACAGCATGTTTTGTTGGGACCAATGGAATGGTACCTTTGTGGTGAAGATCCTGCATTTGGATTTCCAAAACTTGAGCAAGCAAACAAA CCTTCTCATCTTTGTGGTCGTGTTTTTAAAGTAGGAGAGCCTACATATTCTTGCAGAGACTGTGCAGTTGATCCAACTTGTGTTTTGTGC ATGGAGTGCTTTTTGGGAAGTATTCACAGAGATCATCGATATAGGATGACAACATCAGGAGGTGGAGGTTTCTGTGACTGTGGTGATACT GAAGCCTGGAAAGAGGGTCCTTACTGTCAAAAACATGAACTTAACACCTCTGAAATTGAGGAAGAAGAGGATCCTCTTGTTCATTTATCA GAAGATGTGATAGCAAGAACTTATAACATTTTTGCTATTACGTTTCGGTATGCAGTAGAAATATTAACCTGGGAAAAAGAAAGTGAATTG CCAGCAGATTTAGAGATGGTAGAGAAGAGTGACACCTACTATTGCATGCTGTTTAATGATGAGGTTCACACCTATGAACAAGTTATTTAT ACTCTTCAGAAAGCTGTTAACTGTACACAAAAAGAAGCTATTGGTTTTGCAACTACAGTAGATCGAGATGGGCGTAGGTCTGTTCGATAT GGAGATTTTCAGTATTGTGAGCAAGCAAAATCAGTAATTGTGAGAAATACCAGTAGACAGACAAAGCCACTCAAAGTTCAAGTTATGCAT TCGTCTATTGTCGCACATCAGAATTTTGGTTTGAAACTTTTGTCTTGGCTGGGAAGTATTATTGGATATTCAGATGGCCTTCGCCGGATT TTATGTCAAGTTGGTTTACAAGAAGGGCCAGATGGTGAAAACTCTTCTCTAGTGGACAGACTGATGCTTAGTGATTCCAAATTATGGAAA GGTGCTAGGAGTGTATATCATCAGTTGTTCATGAGCAGTCTGCTTATGGATTTGAAATACAAGAAACTATTTGCTGTTCGATTTGCAAAA AATTACCAGCAGTTGCAGAGAGATTTTATGGAGGATGATCACGAGCGAGCAGTGTCGGTGACTGCTCTATCTGTCCAGTTCTTCACCGCA CCTACTCTGGCTCGAATGCTCATCACAGAAGAAAACTTAATGAGCATTATCATTAAGACTTTTATGGATCATTTGAGACATCGAGATGCC CAGGGCAGATTTCAGTTTGAACGATACACTGCTTTACAAGCCTTCAAATTTAGGAGAGTACAGAGCCTTATTTTAGATCTCAAGTATGTG TTAATTAGCAAACCAACTGAATGGTCAGATGAGCTGAGGCAGAAGTTCCTAGAAGGGTTTGATGCCTTTTTGGAATTACTAAAATGTATG CAGGGAATGGATCCAATTACACGTCAAGTAGGACAACATATTGAAATGGAACCAGAGTGGGAAGCAGCCTTCACACTACAAATGAAATTA ACACATGTCATTTCAATGATGCAGGACTGGTGTGCTTCAGATGAAAAAGTGTTAATCGAAGCTTACAAGAAATGTCTCGCTGTACTGATG CAGTGTCATGGTGGTTATACTGATGGTGAACAGCCAATCACACTAAGCATTTGTGGACATTCAGTGGAAACTATCAGATACTGTGTTTCC CAAGAAAAAGTTAGCATTCACCTCCCAGTTTCTCGCTTACTTGCAGGTTTACATGTATTATTAAGCAAAAGTGAAGTGGCATATAAATTT CCAGAGCTCCTACCTCTAAGTGAACTTAGCCCACCCATGTTGATAGAACACCCTCTTAGATGTCTTGTTCTGTGTGCCCAAGTACATGCC GGAATGTGGAGAAGAAATGGGTTCTCTCTAGTAAACCAGATTTATTACTACCATAATGTGAAATGCAGACGTGAGATGTTTGACAAGGAT GTAGTAATGCTTCAGACAGGTGTCTCCATGATGGATCCAAATCATTTCCTGATGATCATGCTCAGCCGCTTTGAACTTTATCAGATTTTC AGTACTCCAGACTATGGAAAAAGATTTAGTTCTGAGATTACCCATAAGGATGTTGTTCAGCAGAACAATACTCTAATAGAAGAAATGCTA TACCTCATTATAATGCTTGTTGGAGAGAGATTTAGTCCTGGAGTTGGACAGGTAAATGCTACAGATGAAATCAAGCGAGAGATTATCCAT CAGTTGAGTATCAAGCCTATGGCTCATAGTGAATTGGTAAAGTCTTTACCTGAAGATGAGAACAAGGAGACTGGCATGGAGAGTGTAATC GAAGCAGTTGCCCATTTCAAGAAACCTGGATTAACAGGACGAGGCATGTATGAACTGAAACCAGAATGTGCCAAAGAGTTCAACTTGTAT TTCTATCACTTTTCAAGGGCAGAACAGTCCAAGGCAGAAGAAGCGCAACGGAAATTGAAAAGACAAAATAGAGAAGATACAGCACTCCCA CCTCCGGTGTTGCCTCCATTCTGCCCTCTGTTTGCAAGCCTGGTTAACATTTTGCAGTCAGATGTCATGTTGTGCATCATGGGAACAATT CTGCAATGGGCTGTGGAACATAATGGATATGCCTGGTCAGAGTCCATGCTGCAAAGGGTGTTACATTTAATTGGCATGGCACTACAAGAA GAAAAACAACATTTAGAGAATGTCACGGAAGAGCATGTAGTAACATTTACCTTCACTCAGAAGATATCAAAACCTGGTGAAGCGCCAAAA AATTCTCCTAGCATACTAGCTATGCTGGAAACACTACAAAATGCTCCCTACCTAGAAGTCCACAAAGACATGATTCGGTGGATATTGAAG ACTTTTAATGCTGTTAAAAAGATGAGGGAGAGTTCACCTACCAGTCCCGTGGCAGAGACAGAAGGAACCATAATGGAAGAGAGTTCAAGG GACAAAGACAAAGCTGAGAGGAAGAGAAAAGCAGAGATTGCCAGACTGCGCAGAGAAAAGATCATGGCTCAGATGTCTGAAATGCAGCGG CATTTTATTGATGAAAACAAAGAACTCTTTCAGCAGACATTAGAACTGGATGCCTCAACCTCTGCTGTTCTTGATCATAGCCCTGTGGCT TCAGATATGACACTTACAGCACTGGGCCCCGCACAAACTCAGGTTCCTGAACAAAGACAATTCGTTACATGTATATTGTGTCAAGAGGAG CAAGAAGTTAAAGTGGAAAGCAGGGCAATGGTCTTGGCAGCATTTGTTCAGAGATCAACTGTATTATCAAAAAACAGAAGTAAATTTATT CAAGATCCAGAAAAATATGATCCATTATTCATGCACCCTGATCTGTCTTGTGGAACACACACTAGTAGCTGTGGGCACATTATGCATGCC CATTGTTGGCAAAGGTATTTTGATTCCGTTCAAGCTAAAGAACAGCGAAGGCAACAGAGATTACGCTTACATACGAGCTATGATGTAGAA AACGGAGAATTCCTTTGCCCCCTTTGTGAATGCTTGAGTAATACTGTTATTCCTCTGCTGCTTCCTCCAAGAAATATTTTTAACAACAGG TTAAATTTTTCAGACCAACCAAATCTGACTCAGTGGATTAGAACAATATCTCAGCAAATAAAAGCATTACAGTTTCTTAGGAAAGAAGAA AGTACTCCTAATAATGCCTCTACAAAGAATTCAGAAAATGTGGATGAATTACAGCTCCCTGAAGGGTTCAGGCCTGATTTTCGTCCTAAG ATCCCTTATTCTGAGAGCATAAAAGAAATGCTAACGACATTTGGAACTGCTACCTACAAGGTGGGACTAAAGGTTCATCCCAATGAAGAG GATCCTCGTGTTCCCATAATGTGTTGGGGTAGCTGCGCGTACACCATCCAAAGCATAGAAAGAATTTTGAGTGATGAAGATAAACCATTG TTTGGTCCTTTACCTTGCAGACTGGATGACTGTCTTAGGTCATTGACGAGATTTGCCGCAGCACACTGGACAGTGGCATCAGTTTCAGTG GTGCAAGGACATTTTTGTAAACTTTTTGCATCACTGGTGCCTAATGACAGCCATGAGGAACTTCCATGCATATTAGATATTGACATGTTT CATTTATTGGTGGGCTTGGTGCTTGCATTTCCTGCGTTGCAGTGTCAGGATTTTTCAGGGATCAGCCTTGGCACTGGAGACCTTCACATT TTCCATCTGGTTACTATGGCACACATCATACAGATCTTACTTACCTCATGTACAGAAGAGAATGGCATGGATCAAGAAAATCCCCCTTGT GAAGAAGAATCAGCAGTTCTTGCTTTGTATAAAACACTTCACCAGTATACGGGAAGTGCCTTGAAAGAAATACCATCCGGCTGGCATCTG TGGAGGAGTGTCAGAGCTGGAATCATGCCTTTCCTGAAGTGTTCTGCTTTATTTTTTCATTACTTAAATGGAGTTCCTTCCCCACCCGAC ATTCAAGTTCCTGGAACAAGCCATTTTGAACATTTATGTAGCTATCTTTCCCTACCAAACAACCTCATTTGCCTTTTTCAAGAAAATAGT GAGATAATGAATTCACTGATTGAAAGTTGGTGCCGTAACAGTGAAGTTAAAAGATATCTAGAAGGTGAAAGAGATGCTATAAGAACCCAC AATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCACCAAGGCTCTGGATATGCTTGACGCGGAAAAATCTGCTATA TTAGGATTACCTCAACCTCTCTTGGAACTCAATGACTCTCCTGTCTTCAAAACCGTCTTGGAAAGAATGCAGCGTTTCTTCTCTACCCTC TATGAAAACTGTTTTCATATCCTAGGGAAGGCAGGCCCTTCCATGCAGCAAGACTTCTATACTGTGGAGGACCTTGCTACCCAGCTTCTC AGCTCAGCCTTTGTCAACTTGAACAATATTCCTGACTACCGACTCAGACCCATGCTTCGTGTCTTTGTAAAGCCTCTGGTGCTCTTCTGT CCCCCAGAGCACTATGAAGCCCTGGTATCCCCCATCCTCGGACCTCTTTTCACCTACCTCCATATGAGGCTTTCTCAGAAATGGCAAGTT ATCAACCAAAGGAGCCTGCTGTGTGGAGAAGATGAGGCTGCAGATGAAAACCCAGAGTCTCAAGAGATGCTGGAGGAGCAACTGGTGAGG ATGTTAACCCGAGAAGTCATGGACCTAATCACGGTTTGCTGTGTTTCAAAGAAGGGTGCTGACCACAGTAGTGCTCCCCCAGCAGATGGA GACGATGAAGAAATGATGGCCACAGAGGTCACCCCCTCAGCTATGGCAGAGCTTACAGACCTGGGCAAATGTCTGATGAAGCATGAGGAT GTTTGTACAGCGCTATTAATTACAGCCTTCAATTCCCTGGCCTGGAAAGATACTCTGTCCTGCCAGAGGACAACCTCACAGCTCTGCTGG CCTCTCCTCAAACAAGTGCTGTCAGGGACACTGCTCGCAGATGCAGTTACGTGGCTTTTCACCAGTGTGCTGAAAGGCTTACAGATGCAC GGGCAGCACGACGGGTGCATGGCTTCCCTGGTCCATCTGGCCTTCCAGATATACGAGGCACTGCGCCCCAGGTACCTGGAGATAAGAGCT GTAATGGAGCAAATCCCTGAAATACAGAAGGACTCACTGGACCAGTTTGACTGCAAGCTTTTAAACCCCTCCCTGCAGAAAGTGGCTGAC AAGCGCCGAAAGGACCAATTCAAACGCCTCATTGCTGGTTGCATTGGGAAACCCTTGGGAGAGCAGTTCCGAAAAGAAGTTCACATTAAG AATCTTCCCTCACTTTTCAAAAAAACAAAGCCAATGCTGGAGACGGAGGTGCTGGACAATGATGGGGGTGGCCTGGCCACCATCTTTGAA CCCTGAATCAAGCTTTTGGGCATCCTTCCTCGGCCTTTCTTGTCATCTCTTCTTTCCCTTTGTAGCCGATCTCTAGGCCCTTCTTGCACT GCCACCTCACTTTCCACCACTGTCAGCCTGGAAAGAGATCCAGGTCTGGAGCTGGAGAGAACAGGCCCTGTGCAGGACCAGAAGTAATTA TACTAAAGTATCAAGAAAGGGAGTTAGGGCTTAAACTATTCTGTCTAGATGTCCCAGATAGTTCCCATTCTACTTGGAGATTTGGCTTTT CCAAGAAAAGCTAGAGCAGAGCAGCCCTTCTCCCACAAGCCCTCCCACCCCCGTGCAGCCACATACCTGTACAGAATGGTAACTAAGGGT GCTGTGCCCAACCCTGCGACTAGCAAGGCTCGCAGCAAGAGCACAGCCCTCAACTACTTGTGCCAGAGTTTCTCTTGGACCACTCCAACT CCCACTGAGCCCTTTTGCTGCTGGGCTGGCAGGAAACTTTCCCCACTCCCTAAGGGGCATGTCTGGGTTAGGTGCTAAGTGCTGAAGAGA ACTTGGTCAGTTCTCTCAACTTTGCTTTGGGCAAGAATCTGGTCACCTGATGGGATCCATGGTACAGGCTACTGCTAAACTTGGCACAGT ATCAAGTATAGTACCTCCAAGGACCAGGGCTGGGAAGTCTTTAGTGCTAACATCCCCTTTAGAGTTCACACATCTTGCCCTTCCATGAAT GACCCCTCAGTCTGGCCTCCCCAGCCTCAAGGTCCACTCAGGCACAAGAGCCACAGTACCCTAGATAGTGTCACATGACACCGTTGTCAT CCAAGGATAATACAGACCAACTAGGCTACATCTGTGATGAGCAGCTAGCAAAGCCGCTGGTCTTCTCCTAGGACTAAGTCCAGGTGCCTT CCACAATCTCATGGTCTTTCAGGTCCCTGGTTACTTTTCTCAAAGGCCATTTCCAAAAGAATACATGCCTTCACATCACAACCTGTACTG TGAGTCCATTCTAGAGGTCACTGAAAGGCCCTGTAAAGAGAGGACATGGATACGGGACCTGGCCCTGAGGTTATTACTGGCCGTAAGGCA GAGTTAATCCATACAGAAACCAGTGTGTCCATGTGCTCTGCACAAAAACAGACCTGTTGTCCATCCAGTCCACTGACAAGAGGGTTTCCC CGAGAGCCGAAGTGGACTGAAGCTACAGTTTTTAGCTGGTGCGGGCCACAGGCAGGGTCAGATTGAGAAGAAGCAAAGCTGGGGAAGCAG AAGTTGGGAGTCTTGTGTTGCTCCCTCTTCCTGTGTGGTGCTCTGGGTTTCTGTGGATCGTGAAGGCGATCTCAAGAGTGTTTCCCTCCA AACCTGATAGCTGCCTATTCCTGTCTGGTTGGGGCTGTGGAGGATGTAGTTGTATTTATTGCATTGTAATATTTTTAACATCCTGTGACT TCATGCTAGAAATTTTCTATTGTTTATAGAAACTTTTTGTAGAAACATTAACTCTAAAGCACATCTGCATGTCAGTAAAAATCTCAGTTT >In-frame_UBR2_ENST00000372901_chr6_42650849_+_XPO5_ENST00000265351_chr6_43501744_-_7840nt TTCTGTGTCCTTCCCTGGGTCAGGGACGAGCCAGTGACTTGACTCTTGGGCGCTAAGCTTGGGAGGGAGCGCAGGAGGCCGCTGTCCTTC CTTTCCGGTTCACGTCACCCTTCTCTCCCTCTGTTGCTCCACCTGCAGCCACTTGGACGGCTCCGGGACTGATTGCCTGGGGCAGGGGTG GCAGTCGAGGCCGCCGGGGCCGAGGTGAGGCTGCAGCTCTCCGGGCGGCGGTAGCGCTGGGGAGGAGGAGGAGAGAAGATGGCGTCGGAG CTAGAGCCAGAGGTGCAGGCCATCGACCGGAGCTTGCTGGAATGTTCGGCCGAGGAGATTGCGGGGAAATGGCTGCAAGCAACTGACCTC ACTAGAGAAGTGTACCAGCATTTAGCCCACTATGTACCCAAAATCTACTGCAGGGGTCCCAACCCTTTTCCACAGAAAGAAGACATGCTG GCACAGCATGTTTTGTTGGGACCAATGGAATGGTACCTTTGTGGTGAAGATCCTGCATTTGGATTTCCAAAACTTGAGCAAGCAAACAAA CCTTCTCATCTTTGTGGTCGTGTTTTTAAAGTAGGAGAGCCTACATATTCTTGCAGAGACTGTGCAGTTGATCCAACTTGTGTTTTGTGC ATGGAGTGCTTTTTGGGAAGTATTCACAGAGATCATCGATATAGGATGACAACATCAGGAGGTGGAGGTTTCTGTGACTGTGGTGATACT GAAGCCTGGAAAGAGGGTCCTTACTGTCAAAAACATGAACTTAACACCTCTGAAATTGAGGAAGAAGAGGATCCTCTTGTTCATTTATCA GAAGATGTGATAGCAAGAACTTATAACATTTTTGCTATTACGTTTCGGTATGCAGTAGAAATATTAACCTGGGAAAAAGAAAGTGAATTG CCAGCAGATTTAGAGATGGTAGAGAAGAGTGACACCTACTATTGCATGCTGTTTAATGATGAGGTTCACACCTATGAACAAGTTATTTAT ACTCTTCAGAAAGCTGTTAACTGTACACAAAAAGAAGCTATTGGTTTTGCAACTACAGTAGATCGAGATGGGCGTAGGTCTGTTCGATAT GGAGATTTTCAGTATTGTGAGCAAGCAAAATCAGTAATTGTGAGAAATACCAGTAGACAGACAAAGCCACTCAAAGTTCAAGTTATGCAT TCGTCTATTGTCGCACATCAGAATTTTGGTTTGAAACTTTTGTCTTGGCTGGGAAGTATTATTGGATATTCAGATGGCCTTCGCCGGATT TTATGTCAAGTTGGTTTACAAGAAGGGCCAGATGGTGAAAACTCTTCTCTAGTGGACAGACTGATGCTTAGTGATTCCAAATTATGGAAA GGTGCTAGGAGTGTATATCATCAGTTGTTCATGAGCAGTCTGCTTATGGATTTGAAATACAAGAAACTATTTGCTGTTCGATTTGCAAAA AACTATGAGCGTTTGCAGAGTGATTATGTGACAGATGACCACGACAGAGAGTTTTCAGTCGCAGACCTCTCGGTTCAGATATTCACGGTT CCTTCACTTGCTCGAATGCTCATCACAGAAGAAAACTTAATGAGCATTATCATTAAGACTTTTATGGATCATTTGAGACATCGAGATGCC CAGGGCAGATTTCAGTTTGAACGATACACTGCTTTACAAGCCTTCAAATTTAGGAGAGTACAGAGCCTTATTTTAGATCTCAAGTATGTG TTAATTAGCAAACCAACTGAATGGTCAGATGAGCTGAGGCAGAAGTTCCTAGAAGGGTTTGATGCCTTTTTGGAATTACTAAAATGTATG CAGGGAATGGATCCAATTACACGTCAAGTAGGACAACATATTGAAATGGAACCAGAGTGGGAAGCAGCCTTCACACTACAAATGAAATTA ACACATGTCATTTCAATGATGCAGGACTGGTGTGCTTCAGATGAAAAAGTGTTAATCGAAGCTTACAAGAAATGTCTCGCTGTACTGATG CAGTGTCATGGTGGTTATACTGATGGTGAACAGCCAATCACACTAAGCATTTGTGGACATTCAGTGGAAACTATCAGATACTGTGTTTCC CAAGAAAAAGTTAGCATTCACCTCCCAGTTTCTCGCTTACTTGCAGGTTTACATGTATTATTAAGCAAAAGTGAAGTGGCATATAAATTT CCAGAGCTCCTACCTCTAAGTGAACTTAGCCCACCCATGTTGATAGAACACCCTCTTAGATGTCTTGTTCTGTGTGCCCAAGTACATGCC GGAATGTGGAGAAGAAATGGGTTCTCTCTAGTAAACCAGATTTATTACTACCATAATGTGAAATGCAGACGTGAGATGTTTGACAAGGAT GTAGTAATGCTTCAGACAGGTGTCTCCATGATGGATCCAAATCATTTCCTGATGATCATGCTCAGCCGCTTTGAACTTTATCAGATTTTC AGTACTCCAGACTATGGAAAAAGATTTAGTTCTGAGATTACCCATAAGGATGTTGTTCAGCAGAACAATACTCTAATAGAAGAAATGCTA TACCTCATTATAATGCTTGTTGGAGAGAGATTTAGTCCTGGAGTTGGACAGGTAAATGCTACAGATGAAATCAAGCGAGAGATTATCCAT CAGTTGAGTATCAAGCCTATGGCTCATAGTGAATTGGTAAAGTCTTTACCTGAAGATGAGAACAAGGAGACTGGCATGGAGAGTGTAATC GAAGCAGTTGCCCATTTCAAGAAACCTGGATTAACAGGACGAGGCATGTATGAACTGAAACCAGAATGTGCCAAAGAGTTCAACTTGTAT TTCTATCACTTTTCAAGGGCAGAACAGTCCAAGGCAGAAGAAGCGCAACGGAAATTGAAAAGACAAAATAGAGAAGATACAGCACTCCCA CCTCCGGTGTTGCCTCCATTCTGCCCTCTGTTTGCAAGCCTGGTTAACATTTTGCAGTCAGATGTCATGTTGTGCATCATGGGAACAATT CTGCAATGGGCTGTGGAACATAATGGATATGCCTGGTCAGAGTCCATGCTGCAAAGGGTGTTACATTTAATTGGCATGGCACTACAAGAA GAAAAACAACATTTAGAGAATGTCACGGAAGAGCATGTAGTAACATTTACCTTCACTCAGAAGATATCAAAACCTGGTGAAGCGCCAAAA AATTCTCCTAGCATACTAGCTATGCTGGAAACACTACAAAATGCTCCCTACCTAGAAGTCCACAAAGACATGATTCGGTGGATATTGAAG ACTTTTAATGCTGTTAAAAAGATGAGGGAGAGTTCACCTACCAGTCCCGTGGCAGAGACAGAAGGAACCATAATGGAAGAGAGTTCAAGG GACAAAGACAAAGCTGAGAGGAAGAGAAAAGCAGAGATTGCCAGACTGCGCAGAGAAAAGATCATGGCTCAGATGTCTGAAATGCAGCGG CATTTTATTGATGAAAACAAAGAACTCTTTCAGCAGACATTAGAACTGGATGCCTCAACCTCTGCTGTTCTTGATCATAGCCCTGTGGCT TCAGATATGACACTTACAGCACTGGGCCCCGCACAAACTCAGGTTCCTGAACAAAGACAATTCGTTACATGTATATTGTGTCAAGAGGAG CAAGAAGTTAAAGTGGAAAGCAGGGCAATGGTCTTGGCAGCATTTGTTCAGAGATCAACTGTATTATCAAAAAACAGAAGTAAATTTATT CAAGATCCAGAAAAATATGATCCATTATTCATGCACCCTGATCTGTCTTGTGGAACACACACTAGTAGCTGTGGGCACATTATGCATGCC CATTGTTGGCAAAGGTATTTTGATTCCGTTCAAGCTAAAGAACAGCGAAGGCAACAGAGATTACGCTTACATACGAGCTATGATGTAGAA AACGGAGAATTCCTTTGCCCCCTTTGTGAATGCTTGAGTAATACTGTTATTCCTCTGCTGCTTCCTCCAAGAAATATTTTTAACAACAGG TTAAATTTTTCAGACCAACCAAATCTGACTCAGTGGATTAGAACAATATCTCAGCAAATAAAAGCATTACAGTTTCTTAGGAAAGAAGAA AGTACTCCTAATAATGCCTCTACAAAGAATTCAGAAAATGTGGATGAATTACAGCTCCCTGAAGGGTTCAGGCCTGATTTTCGTCCTAAG ATCCCTTATTCTGAGAGCATAAAAGAAATGCTAACGACATTTGGAACTGCTACCTACAAGGTGGGACTAAAGGTTCATCCCAATGAAGAG GATCCTCGTGTTCCCATAATGTGTTGGGGTAGCTGCGCGTACACCATCCAAAGCATAGAAAGAATTTTGAGTGATGAAGATAAACCATTG TTTGGTCCTTTACCTTGCAGACTGGATGACTGTCTTAGGTCATTGACGAGATTTGCCGCAGCACACTGGACAGTGGCATCAGTTTCAGTG GTGCAAGGACATTTTTGTAAACTTTTTGCATCACTGGTGCCTAATGACAGCCATGAGGAACTTCCATGCATATTAGATATTGACATGTTT CATTTATTGGTGGGCTTGGTGCTTGCATTTCCTGCGTTGCAGTGTCAGGATTTTTCAGGGATCAGCCTTGGCACTGGAGACCTTCACATT TTCCATCTGGTTACTATGGCACACATCATACAGATCTTACTTACCTCATGTACAGAAGAGAATGGCATGGATCAAGAAAATCCCCCTTGT GAAGAAGAATCAGCAGTTCTTGCTTTGTATAAAACACTTCACCAGTATACGGGAAGTGCCTTGAAAGAAATACCATCCGGCTGGCATCTG TGGAGGAGTGTCAGAGCTGGAATCATGCCTTTCCTGAAGTGTTCTGCTTTATTTTTTCATTACTTAAATGGAGTTCCTTCCCCACCCGAC ATTCAAGTTCCTGGAACAAGCCATTTTGAACATTTATGTAGCTATCTTTCCCTACCAAACAACCTCATTTGCCTTTTTCAAGAAAATAGT GAGATAATGAATTCACTGATTGAAAGTTGGTGCCGTAACAGTGAAGTTAAAAGATATCTAGAAGGTGAAAGAGATGCTATAAGAACCCAC AATACATTATATGCACCAGAAATGCTAGCCAAAATGGCAGAGCCTTTCACCAAGGCTCTGGATATGCTTGACGCGGAAAAATCTGCTATA TTAGGATTACCTCAACCTCTCTTGGAACTCAATGACTCTCCTGTCTTCAAAACCGTCTTGGAAAGAATGCAGCGTTTCTTCTCTACCCTC TATGAAAACTGTTTTCATATCCTAGGGAAGGCAGGCCCTTCCATGCAGCAAGACTTCTATACTGTGGAGGACCTTGCTACCCAGCTTCTC AGCTCAGCCTTTGTCAACTTGAACAATATTCCTGACTACCGACTCAGACCCATGCTTCGTGTCTTTGTAAAGCCTCTGGTGCTCTTCTGT CCCCCAGAGCACTATGAAGCCCTGGTATCCCCCATCCTCGGACCTCTTTTCACCTACCTCCATATGAGGCTTTCTCAGAAATGGCAAGTT ATCAACCAAAGGAGCCTGCTGTGTGGAGAAGATGAGGCTGCAGATGAAAACCCAGAGTCTCAAGAGATGCTGGAGGAGCAACTGGTGAGG ATGTTAACCCGAGAAGTCATGGACCTAATCACGGTTTGCTGTGTTTCAAAGAAGGGTGCTGACCACAGTAGTGCTCCCCCAGCAGATGGA GACGATGAAGAAATGATGGCCACAGAGGTCACCCCCTCAGCTATGGCAGAGCTTACAGACCTGGGCAAATGTCTGATGAAGCATGAGGAT GTTTGTACAGCGCTATTAATTACAGCCTTCAATTCCCTGGCCTGGAAAGATACTCTGTCCTGCCAGAGGACAACCTCACAGCTCTGCTGG CCTCTCCTCAAACAAGTGCTGTCAGGGACACTGCTCGCAGATGCAGTTACGTGGCTTTTCACCAGTGTGCTGAAAGGCTTACAGATGCAC GGGCAGCACGACGGGTGCATGGCTTCCCTGGTCCATCTGGCCTTCCAGATATACGAGGCACTGCGCCCCAGGTACCTGGAGATAAGAGCT GTAATGGAGCAAATCCCTGAAATACAGAAGGACTCACTGGACCAGTTTGACTGCAAGCTTTTAAACCCCTCCCTGCAGAAAGTGGCTGAC AAGCGCCGAAAGGACCAATTCAAACGCCTCATTGCTGGTTGCATTGGGAAACCCTTGGGAGAGCAGTTCCGAAAAGAAGTTCACATTAAG AATCTTCCCTCACTTTTCAAAAAAACAAAGCCAATGCTGGAGACGGAGGTGCTGGACAATGATGGGGGTGGCCTGGCCACCATCTTTGAA CCCTGAATCAAGCTTTTGGGCATCCTTCCTCGGCCTTTCTTGTCATCTCTTCTTTCCCTTTGTAGCCGATCTCTAGGCCCTTCTTGCACT GCCACCTCACTTTCCACCACTGTCAGCCTGGAAAGAGATCCAGGTCTGGAGCTGGAGAGAACAGGCCCTGTGCAGGACCAGAAGTAATTA TACTAAAGTATCAAGAAAGGGAGTTAGGGCTTAAACTATTCTGTCTAGATGTCCCAGATAGTTCCCATTCTACTTGGAGATTTGGCTTTT CCAAGAAAAGCTAGAGCAGAGCAGCCCTTCTCCCACAAGCCCTCCCACCCCCGTGCAGCCACATACCTGTACAGAATGGTAACTAAGGGT GCTGTGCCCAACCCTGCGACTAGCAAGGCTCGCAGCAAGAGCACAGCCCTCAACTACTTGTGCCAGAGTTTCTCTTGGACCACTCCAACT CCCACTGAGCCCTTTTGCTGCTGGGCTGGCAGGAAACTTTCCCCACTCCCTAAGGGGCATGTCTGGGTTAGGTGCTAAGTGCTGAAGAGA ACTTGGTCAGTTCTCTCAACTTTGCTTTGGGCAAGAATCTGGTCACCTGATGGGATCCATGGTACAGGCTACTGCTAAACTTGGCACAGT ATCAAGTATAGTACCTCCAAGGACCAGGGCTGGGAAGTCTTTAGTGCTAACATCCCCTTTAGAGTTCACACATCTTGCCCTTCCATGAAT GACCCCTCAGTCTGGCCTCCCCAGCCTCAAGGTCCACTCAGGCACAAGAGCCACAGTACCCTAGATAGTGTCACATGACACCGTTGTCAT CCAAGGATAATACAGACCAACTAGGCTACATCTGTGATGAGCAGCTAGCAAAGCCGCTGGTCTTCTCCTAGGACTAAGTCCAGGTGCCTT CCACAATCTCATGGTCTTTCAGGTCCCTGGTTACTTTTCTCAAAGGCCATTTCCAAAAGAATACATGCCTTCACATCACAACCTGTACTG TGAGTCCATTCTAGAGGTCACTGAAAGGCCCTGTAAAGAGAGGACATGGATACGGGACCTGGCCCTGAGGTTATTACTGGCCGTAAGGCA GAGTTAATCCATACAGAAACCAGTGTGTCCATGTGCTCTGCACAAAAACAGACCTGTTGTCCATCCAGTCCACTGACAAGAGGGTTTCCC CGAGAGCCGAAGTGGACTGAAGCTACAGTTTTTAGCTGGTGCGGGCCACAGGCAGGGTCAGATTGAGAAGAAGCAAAGCTGGGGAAGCAG AAGTTGGGAGTCTTGTGTTGCTCCCTCTTCCTGTGTGGTGCTCTGGGTTTCTGTGGATCGTGAAGGCGATCTCAAGAGTGTTTCCCTCCA AACCTGATAGCTGCCTATTCCTGTCTGGTTGGGGCTGTGGAGGATGTAGTTGTATTTATTGCATTGTAATATTTTTAACATCCTGTGACT TCATGCTAGAAATTTTCTATTGTTTATAGAAACTTTTTGTAGAAACATTAACTCTAAAGCACATCTGCATGTCAGTAAAAATCTCAGTTT |
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FusionGenePPI for UBR2_XPO5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBR2 | UBE2B, HNRNPA1, UBC, HIST2H2AC, MYC, UBXN7, FAF2, FAF1, UBXN1, UBE2Z, TIRAP, HIST1H2BG, RECQL4, UBE2H, GCFC2, NXPH2, NUDT6, MRM1, POLR2M, SOD2, PLEKHO2, PAM, PLXDC2, TEX33, PON2, UBE2A, CLCC1, METTL15, ALDH18A1, EPPK1, PDP2, EPHA7, SNX18, NDUFS3, PSMC2, NES, MRPL50, PARD6B, SGOL1, FOXJ3, UBXN2B, BAG6, DUSP26, NRP1, SPINK2, HS3ST2, INSL5, SMOC1, HYAL1, GFAP, SIL1, RGS8, CROCC, PAK7, ASB6, CRHBP, HEPACAM2, CCDC130, PNLIPRP1, METTL2A, BRCA1 | XPO5 | PTP4A3, GSTK1, SERINC3, NEK6, PHLDA3, MAGEA6, EEF1A1, RAN, ILF3, NUP214, NUP153, UBC, MYC, ZNF346, SIRT7, MRTO4, UCHL5, NOTCH1, CA9, FN1, VCAM1, SMAD4, ITGA4, MMS19, CLN3, SOX2, EGFR, AARSD1, EFTUD2, ELAC2, HARS, P3H1, MAT2B, NRD1, NSUN2, PDIA6, PFDN5, PPP1R12A, SARS, SERPINE2, SHMT1, SNX5, TTC1, UGDH, ARIH1, BAG1, DUS3L, GTF2E1, PPP3CA, WDR4, CHORDC1, ITGB1BP2, MOV10, NXF1, CLEC12A, VSIG2, NUP98, PPME1, NTRK1, LCA5, HSPA5, RAB11A, KRBOX4, CDC5L, ZNF131, NCR3LG1, RALB, PVR, PTPRA, PTPRN, STOM, FOXA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBR2_XPO5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBR2_XPO5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | XPO5 | C0920269 | Microsatellite Instability | 1 | CTD_human |
| Tgene | XPO5 | C1868672 | NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE | 1 | CTD_human |
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