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Fusion gene ID: 40577 |
FusionGeneSummary for UBQLN1_NLRP5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBQLN1_NLRP5 | Fusion gene ID: 40577 | Hgene | Tgene | Gene symbol | UBQLN1 | NLRP5 | Gene ID | 29979 | 126206 |
| Gene name | ubiquilin 1 | NLR family pyrin domain containing 5 | |
| Synonyms | DA41|DSK2|PLIC-1|UBQN|XDRP1 | CLR19.8|MATER|NALP5|PAN11|PYPAF8 | |
| Cytomap | 9q21.32|9q21.2-q21.3 | 19q13.43 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquilin-1hPLIC-1protein linking IAP with cytoskeleton 1testicular tissue protein Li 219 | NACHT, LRR and PYD domains-containing protein 5NACHT, leucine rich repeat and PYD containing 5mater protein homologmaternal antigen that embryos requirenucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | Q9UMX0 | P59047 | |
| Ensembl transtripts involved in fusion gene | ENST00000376395, ENST00000257468, | ENST00000390649, | |
| Fusion gene scores | * DoF score | 6 X 7 X 3=126 | 3 X 3 X 2=18 |
| # samples | 7 | 3 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: UBQLN1 [Title/Abstract] AND NLRP5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBQLN1 | GO:0031396 | regulation of protein ubiquitination | 12634373 |
| Hgene | UBQLN1 | GO:0031398 | positive regulation of protein ubiquitination | 23307288 |
| Hgene | UBQLN1 | GO:0035973 | aggrephagy | 21143716 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A6YR-01A | UBQLN1 | chr9 | 86292642 | - | NLRP5 | chr19 | 56531741 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000376395 | ENST00000390649 | UBQLN1 | chr9 | 86292642 | - | NLRP5 | chr19 | 56531741 | + |
| In-frame | ENST00000257468 | ENST00000390649 | UBQLN1 | chr9 | 86292642 | - | NLRP5 | chr19 | 56531741 | + |
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FusionProtFeatures for UBQLN1_NLRP5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBQLN1 | NLRP5 |
| As a member of the subcortical maternal complex (SCMC),plays an essential role for zygotes to progress beyond the firstembryonic cell divisions. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 182_210 | 368 | 562 | Domain | STI1 1 |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 212_251 | 368 | 562 | Domain | STI1 2 |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 37_111 | 368 | 562 | Domain | Ubiquitin-like |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 182_210 | 368 | 590 | Domain | STI1 1 |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 212_251 | 368 | 590 | Domain | STI1 2 |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 37_111 | 368 | 590 | Domain | Ubiquitin-like |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 280_602 | 207 | 1201 | Domain | NACHT |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 286_293 | 207 | 1201 | Nucleotide binding | ATP |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 1007_1034 | 207 | 1201 | Repeat | Note=LRR 10 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 1036_1059 | 207 | 1201 | Repeat | Note=LRR 11 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 1064_1092 | 207 | 1201 | Repeat | Note=LRR 12 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 1121_1142 | 207 | 1201 | Repeat | Note=LRR 13 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 704_727 | 207 | 1201 | Repeat | Note=LRR 1 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 730_753 | 207 | 1201 | Repeat | Note=LRR 2 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 780_803 | 207 | 1201 | Repeat | Note=LRR 3 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 809_832 | 207 | 1201 | Repeat | Note=LRR 4 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 836_863 | 207 | 1201 | Repeat | Note=LRR 5 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 865_892 | 207 | 1201 | Repeat | Note=LRR 6 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 893_916 | 207 | 1201 | Repeat | Note=LRR 7 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 950_973 | 207 | 1201 | Repeat | Note=LRR 8 |
| Tgene | >NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 979_1002 | 207 | 1201 | Repeat | Note=LRR 9 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 387_434 | 368 | 562 | Domain | STI1 3 |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 438_470 | 368 | 562 | Domain | STI1 4 |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 546_586 | 368 | 562 | Domain | UBA |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 387_434 | 368 | 590 | Domain | STI1 3 |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 438_470 | 368 | 590 | Domain | STI1 4 |
| Hgene | >UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 546_586 | 368 | 590 | Domain | UBA |
| Tgene | NLRP5 | chr9:86292642 | chr19:56531741 | ENST00000390649 | + | 4 | 15 | 57_148 | 207 | 1201 | Domain | Pyrin |
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FusionGeneSequence for UBQLN1_NLRP5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBQLN1_ENST00000376395_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_1362aa MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDT LSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLL SNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYN ALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTTA PNLVPGVGEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSG IGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCK DWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQ VPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGES ELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPL EVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVD VKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHL WRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALR VSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSW LTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARL GLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHS >In-frame_UBQLN1_ENST00000257468_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_1362aa MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDT LSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLL SNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYN ALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTTA PNLVPGVGEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSG IGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCK DWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQ VPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGES ELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPL EVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVD VKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHL WRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALR VSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSW LTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARL GLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBQLN1_ENST00000376395_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_4086nt ATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCCCGCGGCCGCTGCC TCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAG TTTAAGGAAGAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACC TTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACA AATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCCTTTTGGTTTAGGT GGCCTTGGGGGACTTGCAGGTCTGAGTAGCTTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTG TCTAACCCTGAAATGATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATG GCCAATCCACAAATGCAGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAA CTTGCCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAAT GCTTTAAGGCGCATGTACACAGATATTCAGGAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTG AGCAATACATCCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACAGACTTCCCAG AGTTCATCAGCTTCCAGCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCG CCAAATTTGGTGCCTGGAGTAGGAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACAGCAGCAGAGACAGAAGAACAAGGACATGGA GGTGACACATGGGACTACAAGAGTCACGTGATGACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGAC TGGCCGGAAATGCAAACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCTCGCACGGTGGTTCTGCACGGAAAGTCAGGA ATTGGGAAATCGGCTCTAGCCAGAAGGATCGTGCTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTC CCCGTTAGAGAGATGCAGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAGTGGCCAGACTCCCAGGCTCCGGTGACGGAG ATCATGTCCCGACCAGAAAGGCTGTTGTTCATCATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAA GACTGGGCTGAGAAGCAGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTGCTCCCTGAGTCCTTCCTGATCGTCACCGTC AGAGACGTGGGCACAGAGAAGCTCAAGTCAGAGGTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCAC TTGCTCCTTGAGCGCGGGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATGAACAACCGTGAGCTGCTCGACCAGTGCCAG GTGCCCGCCGTGGGCTCTCTCATCTGCGTGGCCCTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACA GGCCTGCACGCCGCTTTTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGTCTCAATCTGGAGGAAAGAGTTGTCCTGAAG CGCTTCTGCCGTATGGCTGTGGAGGGAGTGTGGAATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCT GAGCTCCGTGCTCTGTTTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTACTACACCTTCTTCCACCTCAGTCTCCAGGAC TTCTGTGCCGCCTTGTACTACGTGTTAGAGGGCCTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATG GAGCTTAAACAGGCAGGCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGCCTCGTGAGCGAAGACGTAAGGAGGCCACTG GAGGTCCTGCTGGGCTGTCCCGTTCCCCTGGGGGTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACC ACCCCAGGAGACACCCTGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTTGTTCGCTTGGCATTAAACAGCTTCCAAGAA GTGTGGCTTCCGATTAACCAGAACCTGGACTTGATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGAT GTCAAAGGGATCTTCCCAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGGATGCGGGATAAGACCCTCATTGAGGAGCAG TGGGAAGATTTCTGCTCCATGCTTGGCACCCACCCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAG ACCCTGTGTGCCAAGCTGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAATGCACAGATTACCCCTGGTGTGCAGCACCTC TGGAGAATCGTCATGGCCAACCGTAACCTAAGATCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAA GCCTTAAAACACCCAAAATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACCCATGCCTGTTACCTGAAGATCTCCCAAATC CTTACGACCTCCCCCAGCCTGAAATCTCTGAGCCTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGA GTCTCCCAGTGCGCCCTGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGTTGCCAGAGTCTGGCCTCAGCCCTCGTCAGC AACCGGAGCTTGACACACCTGTGCCTATCCAACAACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCAC TGTAGTCTGCAGAGGCTGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTTCTTGCACTTGCGCTTATGGGTAACTCATGG CTGACGCACCTGAGCCTTAGCATGAACCCTGTGGAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTC CAGGACCTGGAGTTGGTAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGTGTGATCTCGAGGAGCAGACACCTGAAGAGC CTGGATCTCACGGACAATGCCCTGGGTGACGGTGGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTC GGGTTGAAGGCATGTGGACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCCTGCAACCGGCATCTGACCAGTCTAAACCTG GTGCAGAATAACTTCAGTCCCAAAGGAATGATGAAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGG AAATGGCAGTACCCTGTGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCCCGAGTCGTAATTGACGGTAGTTGGCATTCT >In-frame_UBQLN1_ENST00000257468_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_4086nt ATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCCCGCGGCCGCTGCC TCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAG TTTAAGGAAGAAATCTCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACC TTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACA AATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCCTTTTGGTTTAGGT GGCCTTGGGGGACTTGCAGGTCTGAGTAGCTTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTG TCTAACCCTGAAATGATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATG GCCAATCCACAAATGCAGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAA CTTGCCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAAT GCTTTAAGGCGCATGTACACAGATATTCAGGAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTG AGCAATACATCCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACAGACTTCCCAG AGTTCATCAGCTTCCAGCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCG CCAAATTTGGTGCCTGGAGTAGGAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACAGCAGCAGAGACAGAAGAACAAGGACATGGA GGTGACACATGGGACTACAAGAGTCACGTGATGACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGAC TGGCCGGAAATGCAAACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCTCGCACGGTGGTTCTGCACGGAAAGTCAGGA ATTGGGAAATCGGCTCTAGCCAGAAGGATCGTGCTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTC CCCGTTAGAGAGATGCAGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAGTGGCCAGACTCCCAGGCTCCGGTGACGGAG ATCATGTCCCGACCAGAAAGGCTGTTGTTCATCATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAA GACTGGGCTGAGAAGCAGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTGCTCCCTGAGTCCTTCCTGATCGTCACCGTC AGAGACGTGGGCACAGAGAAGCTCAAGTCAGAGGTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCAC TTGCTCCTTGAGCGCGGGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATGAACAACCGTGAGCTGCTCGACCAGTGCCAG GTGCCCGCCGTGGGCTCTCTCATCTGCGTGGCCCTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACA GGCCTGCACGCCGCTTTTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGTCTCAATCTGGAGGAAAGAGTTGTCCTGAAG CGCTTCTGCCGTATGGCTGTGGAGGGAGTGTGGAATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCT GAGCTCCGTGCTCTGTTTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTACTACACCTTCTTCCACCTCAGTCTCCAGGAC TTCTGTGCCGCCTTGTACTACGTGTTAGAGGGCCTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATG GAGCTTAAACAGGCAGGCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGCCTCGTGAGCGAAGACGTAAGGAGGCCACTG GAGGTCCTGCTGGGCTGTCCCGTTCCCCTGGGGGTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACC ACCCCAGGAGACACCCTGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTTGTTCGCTTGGCATTAAACAGCTTCCAAGAA GTGTGGCTTCCGATTAACCAGAACCTGGACTTGATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGAT GTCAAAGGGATCTTCCCAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGGATGCGGGATAAGACCCTCATTGAGGAGCAG TGGGAAGATTTCTGCTCCATGCTTGGCACCCACCCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAG ACCCTGTGTGCCAAGCTGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAATGCACAGATTACCCCTGGTGTGCAGCACCTC TGGAGAATCGTCATGGCCAACCGTAACCTAAGATCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAA GCCTTAAAACACCCAAAATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACCCATGCCTGTTACCTGAAGATCTCCCAAATC CTTACGACCTCCCCCAGCCTGAAATCTCTGAGCCTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGA GTCTCCCAGTGCGCCCTGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGTTGCCAGAGTCTGGCCTCAGCCCTCGTCAGC AACCGGAGCTTGACACACCTGTGCCTATCCAACAACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCAC TGTAGTCTGCAGAGGCTGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTTCTTGCACTTGCGCTTATGGGTAACTCATGG CTGACGCACCTGAGCCTTAGCATGAACCCTGTGGAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTC CAGGACCTGGAGTTGGTAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGTGTGATCTCGAGGAGCAGACACCTGAAGAGC CTGGATCTCACGGACAATGCCCTGGGTGACGGTGGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTC GGGTTGAAGGCATGTGGACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCCTGCAACCGGCATCTGACCAGTCTAAACCTG GTGCAGAATAACTTCAGTCCCAAAGGAATGATGAAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGG AAATGGCAGTACCCTGTGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCCCGAGTCGTAATTGACGGTAGTTGGCATTCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBQLN1_ENST00000376395_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_4895nt GGAAACTGCGATTTAGTTTTTGGTGAAAGGAGTGGAAAAAAACCATGAACTGACCTACCCCGCCCCATTTTGCTTTTAGTCCTTCACACT GGCTTCGCCTGCACTTTGGGCAATGGAGCGGGAAAGGAAAAGGCACGCAGGCTGAGCTCAAAGTCGCGCCAGCCGGGGATGACTCGGCGA CGCCGCCAGGCGCGTTACCCGGCGTGCTCCGCGCGGCGCCGGCGAAGGGACGTGGGGGAAGGGGCAGGGAGGAGGAAGCGGTGGCTGCTG CGGATGTCGGTGTGAGCGAGCGGCGCCTGAACACACGGCGGCTGCCGAGCGCCTGACCCGGGCCTGCGCCAGAGCCTGCACCGAGCTCCG GGGCCCCACACCCGCTACGGTGGCCCTGCGCCCGTTGCTACTGAGGCGGCGTGCTCTGCATTCTTCGCTGTCCAGGCCTGCCGGCTCTGG TGTCTGCTGGCTCCTCCTTGCTCGCCTGCTCCCTCCTGCTTGCCTGAGTCACCGCCGCCGCCGCCGCCACAGCCATGGCCGAGAGTGGTG AAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAA TCATGAAAGTCACCGTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAAGAAATCT CTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGAA TTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCTGGAAGCA ATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTTG CAGGTCTGAGTAGCTTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTGTCTAACCCTGAAATGA TGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATGGCCAATCCACAAATGC AGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAACTTGCCAGGAATCCAG CAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATGT ACACAGATATTCAGGAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTGAGCAATACATCCTCTG GTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACAGACTTCCCAGAGTTCATCAGCTTCCA GCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCGCCAAATTTGGTGCCTG GAGTAGGAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACAGCAGCAGAGACAGAAGAACAAGGACATGGAGGTGACACATGGGACT ACAAGAGTCACGTGATGACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGACTGGCCGGAAATGCAAA CGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCTCGCACGGTGGTTCTGCACGGAAAGTCAGGAATTGGGAAATCGGCTC TAGCCAGAAGGATCGTGCTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTCCCCGTTAGAGAGATGC AGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAGTGGCCAGACTCCCAGGCTCCGGTGACGGAGATCATGTCCCGACCAG AAAGGCTGTTGTTCATCATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAAGACTGGGCTGAGAAGC AGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTGCTCCCTGAGTCCTTCCTGATCGTCACCGTCAGAGACGTGGGCACAG AGAAGCTCAAGTCAGAGGTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCACTTGCTCCTTGAGCGCG GGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATGAACAACCGTGAGCTGCTCGACCAGTGCCAGGTGCCCGCCGTGGGCT CTCTCATCTGCGTGGCCCTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACAGGCCTGCACGCCGCTT TTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGTCTCAATCTGGAGGAAAGAGTTGTCCTGAAGCGCTTCTGCCGTATGG CTGTGGAGGGAGTGTGGAATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCTGAGCTCCGTGCTCTGT TTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTACTACACCTTCTTCCACCTCAGTCTCCAGGACTTCTGTGCCGCCTTGT ACTACGTGTTAGAGGGCCTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATGGAGCTTAAACAGGCAG GCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGCCTCGTGAGCGAAGACGTAAGGAGGCCACTGGAGGTCCTGCTGGGCT GTCCCGTTCCCCTGGGGGTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACCACCCCAGGAGACACCC TGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTTGTTCGCTTGGCATTAAACAGCTTCCAAGAAGTGTGGCTTCCGATTA ACCAGAACCTGGACTTGATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGATGTCAAAGGGATCTTCC CAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGGATGCGGGATAAGACCCTCATTGAGGAGCAGTGGGAAGATTTCTGCT CCATGCTTGGCACCCACCCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAGACCCTGTGTGCCAAGC TGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAATGCACAGATTACCCCTGGTGTGCAGCACCTCTGGAGAATCGTCATGG CCAACCGTAACCTAAGATCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAAGCCTTAAAACACCCAA AATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACCCATGCCTGTTACCTGAAGATCTCCCAAATCCTTACGACCTCCCCCA GCCTGAAATCTCTGAGCCTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGAGTCTCCCAGTGCGCCC TGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGTTGCCAGAGTCTGGCCTCAGCCCTCGTCAGCAACCGGAGCTTGACAC ACCTGTGCCTATCCAACAACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCACTGTAGTCTGCAGAGGC TGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTTCTTGCACTTGCGCTTATGGGTAACTCATGGCTGACGCACCTGAGCC TTAGCATGAACCCTGTGGAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTCCAGGACCTGGAGTTGG TAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGTGTGATCTCGAGGAGCAGACACCTGAAGAGCCTGGATCTCACGGACA ATGCCCTGGGTGACGGTGGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTCGGGTTGAAGGCATGTG GACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCCTGCAACCGGCATCTGACCAGTCTAAACCTGGTGCAGAATAACTTCA GTCCCAAAGGAATGATGAAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGGAAATGGCAGTACCCTG TGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCCCGAGTCGTAATTGACGGTAGTTGGCATTCTTTTGATGAAGATGACC GGTACTGGTGGAAAAACTGAAGATACGGAAACCTGCCCCACTCACACCCATCTGATGGAGGAACTTTAAACGCTGTTTTCTCAGAGCAAG CTATGCACCTGGGAGTTCCTTCTCAAAGATGGAGAATGATTTCTGATTCTCACAAAGCCCTCAATGGTAGTGATTCTTCTGTGTTCACTC TACGTTGGTTACTGGATTTGAAGGCTAGAGACCTTCAAGTCATAGGACTCAGTATCTGTGAAATGTCCGTCATATCTCAGAGCATATAGA >In-frame_UBQLN1_ENST00000257468_chr9_86292642_-_NLRP5_ENST00000390649_chr19_56531741_+_4626nt GCGGATGTCGGTGTGAGCGAGCGGCGCCTGAACACACGGCGGCTGCCGAGCGCCTGACCCGGGCCTGCGCCAGAGCCTGCACCGAGCTCC GGGGCCCCACACCCGCTACGGTGGCCCTGCGCCCGTTGCTACTGAGGCGGCGTGCTCTGCATTCTTCGCTGTCCAGGCCTGCCGGCTCTG GTGTCTGCTGGCTCCTCCTTGCTCGCCTGCTCCCTCCTGCTTGCCTGAGTCACCGCCGCCGCCGCCGCCACAGCCATGGCCGAGAGTGGT GAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAA ATCATGAAAGTCACCGTGAAGACCCCGAAGGAAAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAAGAAATC TCTAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGCATGGA ATTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCTGGAAGC AATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTT GCAGGTCTGAGTAGCTTGGGTTTGAATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTGTCTAACCCTGAAATG ATGGTCCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATGGCCAATCCACAAATG CAGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATATAATGAGACAAACGTTGGAACTTGCCAGGAATCCA GCAATGATGCAGGAGATGATGAGGAACCAGGACCGAGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATG TACACAGATATTCAGGAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTGAGCAATACATCCTCT GGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACAGACTTCCCAGAGTTCATCAGCTTCC AGCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCCAGTGGCACTTCTGGGCAGAGTACTACTGCGCCAAATTTGGTGCCT GGAGTAGGAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACAGCAGCAGAGACAGAAGAACAAGGACATGGAGGTGACACATGGGAC TACAAGAGTCACGTGATGACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGACTGGCCGGAAATGCAA ACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCTCGCACGGTGGTTCTGCACGGAAAGTCAGGAATTGGGAAATCGGCT CTAGCCAGAAGGATCGTGCTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTCCCCGTTAGAGAGATG CAGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAGTGGCCAGACTCCCAGGCTCCGGTGACGGAGATCATGTCCCGACCA GAAAGGCTGTTGTTCATCATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAAGACTGGGCTGAGAAG CAGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTGCTCCCTGAGTCCTTCCTGATCGTCACCGTCAGAGACGTGGGCACA GAGAAGCTCAAGTCAGAGGTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCACTTGCTCCTTGAGCGC GGGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATGAACAACCGTGAGCTGCTCGACCAGTGCCAGGTGCCCGCCGTGGGC TCTCTCATCTGCGTGGCCCTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACAGGCCTGCACGCCGCT TTTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGTCTCAATCTGGAGGAAAGAGTTGTCCTGAAGCGCTTCTGCCGTATG GCTGTGGAGGGAGTGTGGAATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCTGAGCTCCGTGCTCTG TTTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTACTACACCTTCTTCCACCTCAGTCTCCAGGACTTCTGTGCCGCCTTG TACTACGTGTTAGAGGGCCTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATGGAGCTTAAACAGGCA GGCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGCCTCGTGAGCGAAGACGTAAGGAGGCCACTGGAGGTCCTGCTGGGC TGTCCCGTTCCCCTGGGGGTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACCACCCCAGGAGACACC CTGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTTGTTCGCTTGGCATTAAACAGCTTCCAAGAAGTGTGGCTTCCGATT AACCAGAACCTGGACTTGATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGATGTCAAAGGGATCTTC CCAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGGATGCGGGATAAGACCCTCATTGAGGAGCAGTGGGAAGATTTCTGC TCCATGCTTGGCACCCACCCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAGACCCTGTGTGCCAAG CTGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAATGCACAGATTACCCCTGGTGTGCAGCACCTCTGGAGAATCGTCATG GCCAACCGTAACCTAAGATCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAAGCCTTAAAACACCCA AAATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACCCATGCCTGTTACCTGAAGATCTCCCAAATCCTTACGACCTCCCCC AGCCTGAAATCTCTGAGCCTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGAGTCTCCCAGTGCGCC CTGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGTTGCCAGAGTCTGGCCTCAGCCCTCGTCAGCAACCGGAGCTTGACA CACCTGTGCCTATCCAACAACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCACTGTAGTCTGCAGAGG CTGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTTCTTGCACTTGCGCTTATGGGTAACTCATGGCTGACGCACCTGAGC CTTAGCATGAACCCTGTGGAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTCCAGGACCTGGAGTTG GTAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGTGTGATCTCGAGGAGCAGACACCTGAAGAGCCTGGATCTCACGGAC AATGCCCTGGGTGACGGTGGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTCGGGTTGAAGGCATGT GGACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCCTGCAACCGGCATCTGACCAGTCTAAACCTGGTGCAGAATAACTTC AGTCCCAAAGGAATGATGAAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGGAAATGGCAGTACCCT GTGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCCCGAGTCGTAATTGACGGTAGTTGGCATTCTTTTGATGAAGATGAC CGGTACTGGTGGAAAAACTGAAGATACGGAAACCTGCCCCACTCACACCCATCTGATGGAGGAACTTTAAACGCTGTTTTCTCAGAGCAA GCTATGCACCTGGGAGTTCCTTCTCAAAGATGGAGAATGATTTCTGATTCTCACAAAGCCCTCAATGGTAGTGATTCTTCTGTGTTCACT CTACGTTGGTTACTGGATTTGAAGGCTAGAGACCTTCAAGTCATAGGACTCAGTATCTGTGAAATGTCCGTCATATCTCAGAGCATATAG |
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FusionGenePPI for UBQLN1_NLRP5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBQLN1 | MTOR, NBL1, P4HB, HK2, FAM127B, TRIM32, TFF1, GABRD, TMCO6, PLA2G16, FZD7, CSTF2T, UBQLN1, CD99, IGLC1, RIC8A, SERPINI2, EFEMP2, MIEF2, HSPA13, KLHL42, CSTF2, HGS, PSEN1, PSEN2, UBE3A, HERC3, HERPUD1, PSMD4, ATXN3, EPS15, DNAJB2, RNF185, UBC, INSIG2, RAD23A, BCL2L10, CHGB, APP, SPARC, STMN3, TICAM1, MAP1LC3A, UBXN4, VCP, TARDBP, UBQLN2, GABRA1, GABRB2, GABRB3, GABRA2, GABRA3, GABRA6, GABRB1, HTT, EPS15L1, STAM2, GNB1, ADRM1, RARA, UBQLN4, FAM127A, GKAP1, RASSF5, ZG16, PSMD2, PSMC2, PSMA5, UBE2D2, SSSCA1, AHCYL1, USP34, UBE2A, RAD23B, VPS26A, VPS4B, ATP6V1B2, UBE2B, ZRANB2, UCHL3, UBE4B, USP9X, UBE2D1, UBE2C, SNRNP70, RBMS1, UBXN1, ATP6V1H, UNK, CLNS1A, WDFY1, SFXN1, UBL7, HYPK, ORAI1, SMAD9, PRPF40A, UBL4A, FBXO25, FAS, F8, ABCC2, EP300, FAM86B3P, C1QA, FGF7, NPY, PTN, TNFRSF1A, TNFRSF1B, GIT2, TMEM37, DCTPP1, GAPDH, GNPDA1, HSPA1L, MTHFD1, RAP1GDS1, NUBP1, WIBG, PSMD3, SHFM1, PSMD14, NDE1, CALU, COL1A2, COL10A1, CTAG1B, DEFA6, FCGR2A, FKBP2, FN1, GPX3, GRM2, GYPB, SLC29A2, IGL, IL6ST, MCM7, MLLT6, NME3, NPPA, SERPINE1, PPIB, PPIC, PRB1, SRGN, RPN1, CCL7, SCG5, UBB, UBE2V1, ZMYM4, PNMA1, FAM189A2, LITAF, IST1, NUPL1, PSMD6, AGR2, SMR3B, ACOT7, SCMH1, COLGALT2, IGLV2-14, CTAG2, TXNDC12, HSD17B12, BPIFA1, CYB5R1, GHRL, MIEF1, AGPAT5, ETNK1, CARKD, NGLY1, PBXIP1, MANBAL, XPO4, SIL1, RSRC2, SMIM2, TMUB2, ZNF343, CD99L2, PIK3IP1, C1QTNF2, PRAP1, COMTD1, ERP27, ZG16B, ZFAND2B, ITPRIPL1, AGR3, TMEM31, FAM127C, RNF208, TREX1, MAP3K1, TLR4, PSMA6, PSMA7, CD3D, ASNS, PDCD6, TRIAP1, C12orf10, STMN1, ZMYM3, NTRK1, PARVA, SCG2, RELA, SMURF1, CD47, KDELR1, WBP2, MTNR1A, CYLD, TRIM25, IGF1R, ESYT2, BAG6 | NLRP5 | TXNDC17, DECR1, BECN1, BAG2, STIP1, LRRC1, MATR3, NLRP2, NLRP3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000257468 | - | 6 | 10 | 178_428 | 368 | 562 | UBXN4 |
| Hgene | UBQLN1 | chr9:86292642 | chr19:56531741 | ENST00000376395 | - | 6 | 11 | 178_428 | 368 | 590 | UBXN4 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBQLN1_NLRP5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBQLN1_NLRP5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | UBQLN1 | C0027626 | Neoplasm Invasiveness | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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