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Fusion gene ID: 40558 |
FusionGeneSummary for UBLCP1_CSNK1A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBLCP1_CSNK1A1 | Fusion gene ID: 40558 | Hgene | Tgene | Gene symbol | UBLCP1 | CSNK1A1 | Gene ID | 134510 | 1452 |
| Gene name | ubiquitin like domain containing CTD phosphatase 1 | casein kinase 1 alpha 1 | |
| Synonyms | CPUB1 | CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975 | |
| Cytomap | 5q33.3 | 5q32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin-like domain-containing CTD phosphatase 1CTD phosphatase-like with ubiquitin domain 1CTD-like phosphatase domain-containing proteinnuclear proteasome inhibitor UBLCP1 | casein kinase I isoform alphaCKI-alphaclock regulator kinasedown-regulated in lung cancerepididymis secretory sperm binding protein Li 77p | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8WVY7 | P48729 | |
| Ensembl transtripts involved in fusion gene | ENST00000296786, | ENST00000261798, ENST00000377843, ENST00000515435, ENST00000504676, ENST00000515768, ENST00000606719, ENST00000606299, ENST00000515748, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 7 X 5 X 6=210 |
| # samples | 2 | 7 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UBLCP1 [Title/Abstract] AND CSNK1A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBLCP1 | GO:0006470 | protein dephosphorylation | 21949367 |
| Tgene | CSNK1A1 | GO:0006468 | protein phosphorylation | 18305108 |
| Tgene | CSNK1A1 | GO:0018105 | peptidyl-serine phosphorylation | 25500533 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-ZP-A9D4-01A | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296786 | ENST00000261798 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| Frame-shift | ENST00000296786 | ENST00000377843 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| In-frame | ENST00000296786 | ENST00000515435 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| In-frame | ENST00000296786 | ENST00000504676 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| Frame-shift | ENST00000296786 | ENST00000515768 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| Frame-shift | ENST00000296786 | ENST00000606719 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| 5CDS-intron | ENST00000296786 | ENST00000606299 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
| 5CDS-intron | ENST00000296786 | ENST00000515748 | UBLCP1 | chr5 | 158696077 | + | CSNK1A1 | chr5 | 148876423 | - |
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FusionProtFeatures for UBLCP1_CSNK1A1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBLCP1 | CSNK1A1 |
| Dephosphorylates 26S nuclear proteasomes, therebydecreasing their proteolytic activity. The dephosphorylation mayprevent assembly of the core and regulatory particles (CP and RP)into mature 26S proteasome. {ECO:0000269|PubMed:21949367}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >UBLCP1 | chr5:158696077 | chr5:148876423 | ENST00000296786 | + | 2 | 11 | 3_81 | 51 | 319 | Domain | Ubiquitin-like |
| Hgene | >UBLCP1 | chr5:158696077 | chr5:148876423 | ENST00000296786 | + | 2 | 11 | 133_294 | 51 | 319 | Region | Note=Phosphatase |
| Tgene | CSNK1A1 | chr5:158696077 | chr5:148876423 | ENST00000377843 | - | 8 | 10 | 17_285 | 335 | 338 | Domain | Protein kinase |
| Tgene | CSNK1A1 | chr5:158696077 | chr5:148876423 | ENST00000515768 | - | 9 | 11 | 17_285 | 363 | 366 | Domain | Protein kinase |
| Tgene | CSNK1A1 | chr5:158696077 | chr5:148876423 | ENST00000377843 | - | 8 | 10 | 23_31 | 335 | 338 | Nucleotide binding | ATP |
| Tgene | CSNK1A1 | chr5:158696077 | chr5:148876423 | ENST00000515768 | - | 9 | 11 | 23_31 | 363 | 366 | Nucleotide binding | ATP |
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FusionGeneSequence for UBLCP1_CSNK1A1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000261798_chr5_148876423_-_54aa >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000515435_chr5_148876423_-_54aa >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000504676_chr5_148876423_-_54aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000261798_chr5_148876423_-_162nt ATGGCTCTCCCTATCATTGTAAAATGGGGTGGACAGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAG >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000515435_chr5_148876423_-_162nt ATGGCTCTCCCTATCATTGTAAAATGGGGTGGACAGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAG >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000504676_chr5_148876423_-_162nt ATGGCTCTCCCTATCATTGTAAAATGGGGTGGACAGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000261798_chr5_148876423_-_5144nt AGAGCGGCCACCCAGGGATCGGCGCTATCTGCACAGCGGTTACAGTCTCGGAAAGGCCTGGCTTCTTCGTGGCTTTGTGGAGATCCCTTA CAGCGGCCATTTGATTAGCACCCGAAGAGATTCAAAGGAAGCAGTTGTTCCGTCCCCAACATATTTCCGTTTCAAACCACCCACTTCCGG TTTTTCAGCCGGTTCCGGTCCCGCCCTTCACTTCCGGTCGCTTTCGGTCTCTCAGCGGCCGGTTTCTGCGTCCGCTGCCGCAGGTTCCAC CGCGCTCCAGGTATTTTTTTTTCTGAAGGAAAGCTGCTTCCTCATATGTTTCAAGAATGGCTCTCCCTATCATTGTAAAATGGGGTGGAC AGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAGTTTCTCAAGACCCTTACAGGAGTTCTTCCAGAAC GCCAAAAGTTACTTGGACTCAAAGTTAAAGGTTTCTAAGCATGAATTGAGGAACAGAAGAAGCAGAGCAGATGATCGGAGCAGCATTTGT TTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGGACAACCATTTACTTGGTGTAAAGAACTTAATTTCAG TATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGAATATTAACTGAGATAGTGAAACATGG TGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAAATTGTGCATATGCCAA TTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAGTTGTGA TGGTTGTTAAATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGT TGGCTTCTTGTCTGCAAGCCAGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCT AGAAATAACAGCATCTAAAGTGAAGACTTAAGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCT TGGTATTAAAAAAAAAGCATATTTGTCACAGAAATTTAGTTAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATC ACTGTAAACATCTATATGATCTGGGATTTTGTTTTTATTTTGAAATGGGAGCTTTTTTGTTTACAAGTTCATTAAAAACTAAAAACTGTT TCTGTAAGGAAATGAGATTTTTTTTAAACAACAAAAAATGCCTTGCTGACTCACTATTAAATAAAAATCTCCCCAATTTTTTGATAGACT ACTTCAAGCCATTTGTTACATGGTATTCCTTTGCAAGTCAATTTAGGTTTCGTGTTATAACTTTTCCTCTTTTTTTAAGAAAAATGAAAA AAGTAATTCTTTTGTCTGAAGGGGAAAGGCATTCTTTCATTTTTTTCTTTTTTTTTTTTTTTTTTTATGACTTGCAGGCACAATATCTAG TACTGCAACTGCCAGAACTTGGTATTGTAGCTGCTGCCCGCTGACTAGCAGCTGGACTGATTTTGAATAAAAATGAAAGCATTAAAGGGT TTCCCTACAAAACATTTTTCTTTAAAATACTTTTGAAATGGCTATAAGCAGTTGACTTTCACCCTTGGAGAGCATCACACTGTGTGAGGT TCAGTGATTGTTGACCCTCCCCAGCCCCTCCTGCTTCTTTAAGTTATCTGTGTGCGTGCGCTTCCTCTCAATCTTCTTTGCACGCTCATT TCTTTTTCTCTGACCCATGAGAAAGGAAAACTTACTGATGATAATTTTTAAATAGTGTAATTTATTCATTTATAGCATGTCAGGATAAAT TAAAAGAACATTTGTCTGGAAATGCTGCCGGGAGCCTATTGTGTAAATGTAGGTATTTTGTAAAATAACCTTGAAATTGTAAATTGACAC GTGTTTGGTCAGATTGTGTCAAGTTTAATTTGTTTTGTTTTCTTTTTTCTTTTTTTTATTTGAAAACTACTTTAGCAATAATTAATTCCA TGATTATCACATTCTGCCATTAAGGGATATTAGTACCGTAATACTGAAGAAATTTTATTAAGTCTGAACTTCTGGGGTAGGCAGCTTCTT TGTTTCTTTTCTATCCACCCTTGTCGGTTGAGGTATTTGTTTCTTGACTAATAAACCCTTTGATACTTTTAGCCAGAAATCAGTCTCATA AAGCTATTTTTGAGTATAGTTTGTGTAAAATAAAAATGTTTAGCTTTGGTAATAACTTCCAAGCTGAACTCCCTCTAGCAAGATATTTTT CAGTGCTTTTATTTACTATGCACTTAGACTATGCACTTTTTCTGAAATATTTTTGTAACACTTTTTTGTATTTTTGCCATTTGAAAAGGT TGTGGTGTAGTTGGTCTGTAATTAAGTTGCAGATTTAAAACTGCTGTTAGCTTTGTAAATCAAAATATAGGTGTTTTTTGTCCTGGTATA TCGTCATTCCATCTGCAGCTGGAGCTGGAATCCCATTGATCTTCTAGCTACCATTCATTTTCTTCACTGTTCACAAAAGAAGAGTGTGAA ATTCAGTGAATGCTGTTACTAATCCTGTTACGAGATGAATCTCATTTCACCAAAATTAAATTATGTTTTTCCGCTAAAATGATGATACAA GTTGAAGACACATCACTCTGAAATTGGAAGACCTCACCACTTAAGGCTCCACAGTGGCTTACTCAGCTGAACTCTAGGTTACTACTCTTT ACTTTGTTCACCCATTGGGGGGTGCAGTTTTTTTAAAATGTTGGGAGATGGCCATTCTAACTACTGTTGAATGTCTCTGTTTTGGGAAGG TATAACAAGAAATAAAAAAGAATATATATGAAGGGAGAGACTGGTTATCTCCTCCCATATGGTTGTGCTTATCCTCTTATGGCTTACAAA TGAATATTTGGAGGTTTGCTTTCACAATGATTTCCCATCAACAAATATTTTTAGTAGGATTTTTCCTGTTTCTGTTAGTCCTTGCAGTAC TCATAAATGTTTTAAGCTGAGCATACTGTAATAGTCATAAGTTTAATTTCATTATAATAAAAATAATCAAACAAAAGGACTTTAGAACCC AAGACAATGAGCTAGTTTTCCCTAAAGTTTGCTGAACTATTAAGGAATATGTTCTTATAGCTTTTGACTAGAATGAGTCATGGGAATTCT AAGAAGGGATGGCCTAGACATTTTTAGCTCAGTTAAATTCAGCATTTAATGCAGGTGAGTTCCTGGGTCGTTTTCCAACTAGTCTGGAAC AGTCTGGTTCTGACTCAAACTGGTATAAAGCATTATTTTAGGTTTTCTCTTTGCCAGTTTTTAAGCAGTTATAACCATGTAAATCAAGAT GTGAGGACATCTATATGAAGTATAGTAAAGAAGTGGTGTCAGCAGATCAATATGTGTGTCCTGGGTGTGCTGCTCTCTTAAGTGAGACTT TGTGAGACTATACTTTAAATGCATTATTACCATTGCTTACATTTTGGGGGATTTTCTTCCTCCTCAAAACTTCCATTTCTATTGTAATAT TCTTAATGACAATCTTTTTTTTTTTTTAGCAGTGTATGTTTGAAACAGCCAAAGATGGCGATGAACCAAGTGTAAATTGATCTAAGCAGC CCATGCAGTTTGTGTTGAATCAACAAACAGTGTATTGTTGAAGTGAAATTATTTTCTGAAATGACTTGTTAGACCAGTTTTGAGGACATA CTCAAAAGTAGAGTAATAATGGCTCCTGGGATGGAGAAATATGAGATGAACCTGGAACATTCTATTATGGTGCCACAAAGGAAATCTAAA AAAAAAAAAAAAAAAAAAAGTGGTTGGCTAGGAGCAGTGGCACACGCCTGTGATTCCAGCACTTTGGGAGGCCGAAGTGGGCAGGAGTTC AAGACCAGCCTGGCCAACATAGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGGGCGCCTGTAATCCCAGC TTTTCAAGAGGCTGAGGCAGAAGAATCGCTTGAACCCGGGAGATGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGG CGTTGCAGTGAGACTCCGTCTCAACAACAACAAAAAGGTGGATACATGTCAAAAGGGCACAGGAGCCACTTGAAGGATTATACTTGCTAA ATCTGTGTCAATTATCAAAATAAACTGGTAGCAACGTTACAACTCACTGAATAAGATACCATGATTCCATGTTGACTTAAAAATGGAGAG AAGAGAAAGCTCTAACTTGAATGTCAGCTAATTTAAGGTGAAAGGATTTTATGTGTTAGAAAAATCACCATTTTGCAAACTAGTTTTCAG AATCCTTAATATATGTCATCTCTTTTATTCCTCATAACAGTAATAAGAAACAGTTAACTGTTTCAGAAAAGAGTGGGGCTGCCCAAGGCA AGGCATGTTGGTAATTGGTAAGCTTTATAGAGCCAAGACCTCAACCTGATTTTCTTGCTTTCATGCAGTTAAGCCATGGTGCTCCTCTTG TTATATCACCCTTTTAAACCCAGAGATTGATAGTATTAGCCATCATTTGCTGAGTGTCATGCACTATTCTAAGTGCTTTACATGTATTTG CCTAATCAGCGCCCTGTGAAGTACATCCTGTCTCCATTTTGCATATAAGGATACCAAAGCACAGAGTTGGAGGGAAGATAGTTATATTCC CTTACTTTATTTATTTATTTTTTTGAGACAGGGTCTCGCACTGTCGCCCAGGCTTGAGTGCTATAAGACCTTAAGTTTCCCCTTTCAAAG TAGTTTATAGTGTCTAAATATCTTACATAAAAGTATATATCAAATAGGGTGGCAGTCTGGAAAGATTTAAAATCCAGAATGACTGGAAGG TTGGGCAACTAAGATTTCTTAAATTGCAGCTGTTTTCAACATAGATGTGTTGTAGAGTCTTTTCGGTTTCAAAATTAAATTGACTATAAA >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000515435_chr5_148876423_-_1287nt AGAGCGGCCACCCAGGGATCGGCGCTATCTGCACAGCGGTTACAGTCTCGGAAAGGCCTGGCTTCTTCGTGGCTTTGTGGAGATCCCTTA CAGCGGCCATTTGATTAGCACCCGAAGAGATTCAAAGGAAGCAGTTGTTCCGTCCCCAACATATTTCCGTTTCAAACCACCCACTTCCGG TTTTTCAGCCGGTTCCGGTCCCGCCCTTCACTTCCGGTCGCTTTCGGTCTCTCAGCGGCCGGTTTCTGCGTCCGCTGCCGCAGGTTCCAC CGCGCTCCAGGTATTTTTTTTTCTGAAGGAAAGCTGCTTCCTCATATGTTTCAAGAATGGCTCTCCCTATCATTGTAAAATGGGGTGGAC AGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAGTTTCTCAAGACCCTTACAGGAGTTCTTCCAGAAC GCCAAAAGTTACTTGGACTCAAAGTTAAAGGTTTCTAAGCATGAATTGAGGAACAGAAGAAGCAGAGCAGATGATCGGAGCAGCATTTGT TTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGGACAACCATTTACTTGGTGTAAAGAACTTAATTTCAG TATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGAATATTAACTGAGATAGTGAAACATGG TGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAAATTGTGCATATGCCAA TTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAGTTGTGA TGGTTGTTAAATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGT TGGCTTCTTGTCTGCAAGCCAGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCT AGAAATAACAGCATCTAAAGTGAAGACTTAAGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCT TGGTATTAAAAAAAAAGCATATTTGTCACAGAAATTTAGTTAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATC >In-frame_UBLCP1_ENST00000296786_chr5_158696077_+_CSNK1A1_ENST00000504676_chr5_148876423_-_1287nt AGAGCGGCCACCCAGGGATCGGCGCTATCTGCACAGCGGTTACAGTCTCGGAAAGGCCTGGCTTCTTCGTGGCTTTGTGGAGATCCCTTA CAGCGGCCATTTGATTAGCACCCGAAGAGATTCAAAGGAAGCAGTTGTTCCGTCCCCAACATATTTCCGTTTCAAACCACCCACTTCCGG TTTTTCAGCCGGTTCCGGTCCCGCCCTTCACTTCCGGTCGCTTTCGGTCTCTCAGCGGCCGGTTTCTGCGTCCGCTGCCGCAGGTTCCAC CGCGCTCCAGGTATTTTTTTTTCTGAAGGAAAGCTGCTTCCTCATATGTTTCAAGAATGGCTCTCCCTATCATTGTAAAATGGGGTGGAC AGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTGCTCGATCTCAAACAGTTTCTCAAGACCCTTACAGGAGTTCTTCCAGAAC GCCAAAAGTTACTTGGACTCAAAGTTAAAGGTTTCTAAGCATGAATTGAGGAACAGAAGAAGCAGAGCAGATGATCGGAGCAGCATTTGT TTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGGACAACCATTTACTTGGTGTAAAGAACTTAATTTCAG TATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGAATATTAACTGAGATAGTGAAACATGG TGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAAATTGTGCATATGCCAA TTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAGTTGTGA TGGTTGTTAAATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGT TGGCTTCTTGTCTGCAAGCCAGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCT AGAAATAACAGCATCTAAAGTGAAGACTTAAGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCT TGGTATTAAAAAAAAAGCATATTTGTCACAGAAATTTAGTTAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATC |
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FusionGenePPI for UBLCP1_CSNK1A1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBLCP1 | PSMD2, TSC22D4, PRPSAP1, ZFAND5, SHFM1, FSD1, NUDT6, ERP29, TARS, COLGALT1, PAAF1, PSMB2, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, PSMD1, PSMD11, PSMD12, PSMD13, PSMD14, PSMD3, PSMD4, PSMD6, PSMD7, PSMD8, UCHL5, GTF2E2, FGB, PSMD10 | CSNK1A1 | HMGB1, HMGB2, RCC1, PPP1R14A, SYT9, ERF, ADAP1, KPNA2, PPP2CA, ACTA1, AXIN1, TNFRSF1B, CHRM3, APC, PHLPP1, MDM4, MALT1, BCL10, NFKBIA, MDM2, TP53, E2F1, COPS5, ELAVL1, SH3KBP1, CDC25A, PDE4D, HSPA4, HSP90AA1, GLI3, MAPT, SNCA, PIP5K1A, CPSF6, PPP1CC, VCAM1, YWHAE, ITGA4, HNRNPC, GNB2, RPA3, RPA2, RPA1, FAM83G, BACH1, SEC16A, HMMR, CSNK1D, CSNK1E, SEC13, DYNLL1, ACACA, SEC23B, FAM83B, ZNF618, MZT2B, MZT2A, FAM83H, USP34, EPM2AIP1, DYNLL2, SNX22, UNC45A, FAM83D, RASAL2, DBR1, SNX24, EGFR, TIAM1, OCLN, SIK2, BTRC, C1orf111, NFATC3, TEX264, FAM170A, NTRK1, PCM1, CEP170, CEP128, CEP135, NIN, XPO1, CLTC, XRCC6, GTSE1, MYO18A, CARD11, NFATC1, SQSTM1, ATOH1, CRBN, CDH1, ZDBF2, SSMEM1, GAPVD1, POTEC, LRP5, HERC1, POTEB3, ARHGAP22, LRP6, TTC9C, NCKIPSD, WEE1, KCTD3, KIF13B, BCR, CGN, ZBTB21, DENND4C, KSR1, GIGYF1, CBY1, WDR92, FOXA1, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBLCP1_CSNK1A1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBLCP1_CSNK1A1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CSNK1A1 | C0023493 | Adult T-Cell Lymphoma/Leukemia | 1 | CTD_human |
| Tgene | CSNK1A1 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
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