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Fusion gene ID: 40449 |
FusionGeneSummary for UBE2K_FAM216B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBE2K_FAM216B | Fusion gene ID: 40449 | Hgene | Tgene | Gene symbol | UBE2K | FAM216B | Gene ID | 3093 | 144809 |
| Gene name | ubiquitin conjugating enzyme E2 K | family with sequence similarity 216 member B | |
| Synonyms | E2-25K|HIP2|HYPG|LIG|UBC1 | C13orf30 | |
| Cytomap | 4p14 | 13q14.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin-conjugating enzyme E2 KE2 ubiquitin-conjugating enzyme KE2(25K)HIP-2huntingtin-interacting protein 2ubiquitin carrier proteinubiquitin conjugating enzyme E2Kubiquitin-conjugating enzyme E2(25K)ubiquitin-conjugating enzyme E2-25 KDAubiqu | protein FAM216B | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | P61086 | Q8N7L0 | |
| Ensembl transtripts involved in fusion gene | ENST00000261427, ENST00000295963, ENST00000438068, ENST00000503368, ENST00000445950, | ENST00000537894, ENST00000313851, | |
| Fusion gene scores | * DoF score | 9 X 6 X 9=486 | 1 X 1 X 1=1 |
| # samples | 10 | 1 | |
| ** MAII score | log2(10/486*10)=-2.28095631383106 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: UBE2K [Title/Abstract] AND FAM216B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBE2K | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 24882218 |
| Hgene | UBE2K | GO:0010994 | free ubiquitin chain polymerization | 24882218 |
| Hgene | UBE2K | GO:0070936 | protein K48-linked ubiquitination | 20061386 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-86-A4P7-01A | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000261427 | ENST00000537894 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000261427 | ENST00000313851 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000295963 | ENST00000537894 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000295963 | ENST00000313851 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| intron-3CDS | ENST00000438068 | ENST00000537894 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| intron-3CDS | ENST00000438068 | ENST00000313851 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000503368 | ENST00000537894 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000503368 | ENST00000313851 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000445950 | ENST00000537894 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
| In-frame | ENST00000445950 | ENST00000313851 | UBE2K | chr4 | 39700010 | + | FAM216B | chr13 | 43360899 | + |
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FusionProtFeatures for UBE2K_FAM216B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBE2K | FAM216B |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >UBE2K | chr4:39700010 | chr13:43360899 | ENST00000261427 | + | 1 | 7 | 160_200 | 21 | 201 | Domain | UBA |
| Hgene | >UBE2K | chr4:39700010 | chr13:43360899 | ENST00000445950 | + | 1 | 6 | 160_200 | 21 | 158 | Domain | UBA |
| Hgene | >UBE2K | chr4:39700010 | chr13:43360899 | ENST00000503368 | + | 1 | 5 | 160_200 | 21 | 150 | Domain | UBA |
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FusionGeneSequence for UBE2K_FAM216B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_128aa MANIAVQRIKREFKEVLKSEEALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_384nt ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTAC TTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTG CTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAA AGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_3425nt ACGCGAGCTCGTGGCTCGGGCGTATGGGGGCTCCAACGGGAGCGGCTGCGCCGCCCGGCCGGGTCAACGTCGTGCGCATGCGCCGACCCG GCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGG TCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAG CTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAG GGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTC AGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCA AGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTA GGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATC TAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAATTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAA TTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTT AAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCC AGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCATGTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCA TAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAAT TTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACTTTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTG ATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAATTCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAA TATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAG TGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTATATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGT CACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTTGAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCT GAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTATCTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGA TTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTA GTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTGGGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCT GGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGG GATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGG GCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTTAGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATC TAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGCTGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGG CTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAAGAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTC TCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTACTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGG TGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTG TTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATACATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAAT TGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAATAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAG ACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGA TGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGGTACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGG TCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAATATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTT CTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACATATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAA TCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGCTATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAG CCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTTGAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACC TGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTTTTTTAAAACAATTTTTATGTATAATTTATATGCAATAAATGCCCTCAA >In-frame_UBE2K_ENST00000261427_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_3425nt ACGCGAGCTCGTGGCTCGGGCGTATGGGGGCTCCAACGGGAGCGGCTGCGCCGCCCGGCCGGGTCAACGTCGTGCGCATGCGCCGACCCG GCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGG TCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAG CTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAG GGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTC AGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCA AGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTA GGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATC TAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAATTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAA TTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTT AAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCC AGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCATGTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCA TAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAAT TTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACTTTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTG ATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAATTCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAA TATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAG TGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTATATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGT CACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTTGAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCT GAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTATCTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGA TTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTA GTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTGGGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCT GGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGG GATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGG GCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTTAGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATC TAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGCTGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGG CTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAAGAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTC TCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTACTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGG TGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTG TTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATACATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAAT TGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAATAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAG ACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGA TGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGGTACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGG TCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAATATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTT CTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACATATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAA TCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGCTATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAG CCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTTGAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACC TGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTTTTTTAAAACAATTTTTATGTATAATTTATATGCAATAAATGCCCTCAA >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_3360nt AACGTCGTGCGCATGCGCCGACCCGGCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGG TAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGT GGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTG AAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTG CAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGA GATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTA CTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGA AGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAATTTCTAATATAAACCCCAGACCT AAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATA ACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAA AGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCATGTATACATTTTGAAAATATACAA AACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCT TCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACTTTGTGTCATCTTGAAACATGCAC TTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAATTCATGCACACATCTTTCCCTGGC AGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCA AAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTATATTTAATGGTTATTTTCATCAC CAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCT TCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTTGAGGTGGAATATAAATTTTATTG ACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTATCTTCTCTTTGCAATCATGAACAT ATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGG AATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTGGGGTCATTCACTTAATCATAAAG AAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAA GAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACT AGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTTAGACTTTTTTTTTTGATGAGCAT AGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGCTGCATCCCTGTATCAAAAATCTC AGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAAGAAGGACAAATAGATCTAAGTTG GGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTACTTGAAACTTAAAGAAATGTGAT TGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTT TAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATACATTATCAGAACTTAAGTCCTGGA GATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAATAATACTCTTTGAATAATAATGA GGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTA GCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGGTACACTGGAAAGAATTTGAAAAC AATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAATATCAGTGATAAAGTATTCATCCC CCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACATATATGTAAGCTTCAAAGTAGCA CATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGCTATATAGTTGGCTCTCAGTACAT ATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTTGAAATAAACAATGATTATACCAT GATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTTTTTTAAAACAATTTTTATGTATA >In-frame_UBE2K_ENST00000295963_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_3360nt AACGTCGTGCGCATGCGCCGACCCGGCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGG TAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGT GGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTG AAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTG CAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGA GATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCATGACAAGAAGATGTCCATCAGTA CTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGA AGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAATTTCTAATATAAACCCCAGACCT AAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATA ACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAA AGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCATGTATACATTTTGAAAATATACAA AACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCT TCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACTTTGTGTCATCTTGAAACATGCAC TTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAATTCATGCACACATCTTTCCCTGGC AGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCA AAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTATATTTAATGGTTATTTTCATCAC CAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCT TCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTTGAGGTGGAATATAAATTTTATTG ACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTATCTTCTCTTTGCAATCATGAACAT ATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGG AATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTGGGGTCATTCACTTAATCATAAAG AAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAA GAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACT AGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTTAGACTTTTTTTTTTGATGAGCAT AGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGCTGCATCCCTGTATCAAAAATCTC AGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAAGAAGGACAAATAGATCTAAGTTG GGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTACTTGAAACTTAAAGAAATGTGAT TGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTT TAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATACATTATCAGAACTTAAGTCCTGGA GATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAATAATACTCTTTGAATAATAATGA GGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTA GCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGGTACACTGGAAAGAATTTGAAAAC AATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAATATCAGTGATAAAGTATTCATCCC CCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACATATATGTAAGCTTCAAAGTAGCA CATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGCTATATAGTTGGCTCTCAGTACAT ATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTTGAAATAAACAATGATTATACCAT GATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTTTTTTAAAACAATTTTTATGTATA >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_3306nt GATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGA GGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCG GTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATG AGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACT CAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGG AAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTC AGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAA TGACAGTGAATAATTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGA GCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGG ATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCT AGCAAACTATCATGTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCA GCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACC TGGCTTGATCACTTTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACA TGGGTAAGAGAATTCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCA TGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGT ATTGCATTAGTTATATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTC ACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATG AAAGGAATTGGTTGAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAA AAAAAATCATTATCTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCAC TACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAAT ACTGACCTTGCTGGGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTA CAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGC AGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCT GCACTTTTATCTTAGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACT TACAATTCTAAGCTGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGT CACAGGTCCATAAGAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGC ACTTGAGACCTTACTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAA ACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCAC AATGTCAATATACATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGC GGTAGGCAATCAATAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCT AGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGC AGGGAATAGAGGGTACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGC AATTCTAAATAATATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGT TTTAAATAATACATATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCA GGGAATATCCTGCTATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTT AAATGATGGATTTGAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTG >In-frame_UBE2K_ENST00000503368_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_3306nt GATTCCACACTGAGGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGA GGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCG GTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATG AGGATTTACAACTCCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACT CAACGGGAAGCCTTGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGG AAAACTTCAGCCATGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTC AGGAACTGAGACTTGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAA TGACAGTGAATAATTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGA GCAATGGAGCCGAGAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGG ATTAGAACCTCCTAGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCT AGCAAACTATCATGTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCA GCAACAATTGGCCTGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACC TGGCTTGATCACTTTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACA TGGGTAAGAGAATTCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCA TGTCCAACCTTTCTGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGT ATTGCATTAGTTATATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTC ACCAGTGCTCATGTAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATG AAAGGAATTGGTTGAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAA AAAAAATCATTATCTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCAC TACTTCCAAGCTCCTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAAT ACTGACCTTGCTGGGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTA CAGTTCTAAGTGAGAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGC AGAGAGGTTGGTGGGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCT GCACTTTTATCTTAGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACT TACAATTCTAAGCTGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGT CACAGGTCCATAAGAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGC ACTTGAGACCTTACTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAA ACAAAGGGGAAGGAAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCAC AATGTCAATATACATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGC GGTAGGCAATCAATAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCT AGAGTCCCAGTAACCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGC AGGGAATAGAGGGTACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGC AATTCTAAATAATATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGT TTTAAATAATACATATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCA GGGAATATCCTGCTATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTT AAATGATGGATTTGAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTG >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000537894_chr13_43360899_+_3293nt GGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCG GCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCA AGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACT CCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCT TGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCA TGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACT TGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAA TTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGA GAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCT AGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCAT GTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCC TGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACT TTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAAT TCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTC TGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTA TATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATG TAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTT GAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTAT CTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTC CTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTG GGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGA GAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTG GGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTT AGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGC TGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAA GAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTA CTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGG AAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATAC ATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAA TAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAA CCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGG TACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAAT ATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACA TATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGC TATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTT GAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTT >In-frame_UBE2K_ENST00000445950_chr4_39700010_+_FAM216B_ENST00000313851_chr13_43360899_+_3293nt GGCGAGCGCGGCGGCCGGGGTGGTAGTGGCAGTGTTCGTGTGCTCAGGTCTGAATCGCCGAGGGAGGAGGCGGTGGAGGAAGAGGTGGCG GCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCA AGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGGCCCTCAACCAAGGGCAACAGCGCTACTTTTACAGCATTATGAGGATTTACAACT CCAGGCCCCAGTGGGAGGCCCTGCAGACCCGCTACATTCACAGCCTTCAGCACCAACAGCTGCTTGGCTATATTACTCAACGGGAAGCCT TGTCTTATGCTCTTGTACTTAGAGATTCAACCAAGAGAGCCTCAGCCAAGGTAGCTCCTCAAAGAACCATTCCCCGGAAAACTTCAGCCA TGACAAGAAGATGTCCATCAGTACTACCTGTATCTGTGGTTCTACCTAGGGCCCAAAGTAAAAGGCGCCAAGTGCTCAGGAACTGAGACT TGGCAGCATTTTCAGAAACAGGAAGTTTGCCCATGTATCCCTGGTATCTAGTGGGTGCTTTGTGCATATTTGTTGAATGACAGTGAATAA TTTCTAATATAAACCCCAGACCTAAAAATAATCTCTGATTCATATAAATTTTGCCAGCAAGACCAAGAGGTTTAAGAGCAATGGAGCCGA GAGTAAGCAAGCCTTTCCACATAACATCCGTAGAGTAAAAGGACTTTTAAAGCTTTCAAAGTAAAAGTTTACTTTGGATTAGAACCTCCT AGAGAAGTCCCCAAAACAGTGAAAGGGGACAAGTGACCAGAAAGGGCCAGGTCCTCTGTCACTGGGTGACCATTTCTAGCAAACTATCAT GTATACATTTTGAAAATATACAAAACAACACAGGATTAACACTGATCATAGAGGGCTTACAAAATCATATCATCCCAGCAACAATTGGCC TGTGCATTTCCTTCCTCTCCTCTTCCCCATCAGGCAATGGCATTTAATTTAGCCCCAAAGCTCTTCTAGTTCTCACCTGGCTTGATCACT TTGTGTCATCTTGAAACATGCACTTATCAGTCTACCACAGCTGAATTGATTTTATGGAGCTGTAACTGGCCTTGACATGGGTAAGAGAAT TCATGCACACATCTTTCCCTGGCAGCTGAAGAAACACTCTTAAAAGAATATGAAATAACCCCGAAGACTTTATTTCATGTCCAACCTTTC TGTGGCCTCAAATGTTTTAAGCAAAGCACATAAAACTATACTAAGCAGTGAGTCAGTTCATCATACAAAGGCATAGTATTGCATTAGTTA TATTTAATGGTTATTTTCATCACCAGAGATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTAAAAATCAGTCACCAGTGCTCATG TAAAGTCAAAACAAAAAAATGCTTCTTCCTCATCATTGTAAAATACGTCACCCCATTCAAATCAGCTGATGCCTATGAAAGGAATTGGTT GAGGTGGAATATAAATTTTATTGACAAGGGATGTGCTAACATTGATCTGAAAGGAATATGCTGCATTATTATCAGAAAAAAAATCATTAT CTTCTCTTTGCAATCATGAACATATAAGATATAAAAATTGTCATGAGATTCTGAACACTAGTATTGAGGTCCAGCACTACTTCCAAGCTC CTATCTGACTTTTCTTTGGGAGGAATGGGAAGTGTGGTTGGCCCACTAGTCTGATAAGAAGTCTTGGTGAAGCTAATACTGACCTTGCTG GGGTCATTCACTTAATCATAAAGAAGCTTCTTGACCTCTGCAAATTCTGGCCCTGACATGTATTCTAAATACCTTTACAGTTCTAAGTGA GAAATTGTTACATAGGCTTAGAAGAAGAAAAGACTCCAGTGGGACTGGGATGAGCTGCGTGGTAGCCCTCATAAAGCAGAGAGGTTGGTG GGAGACCTAACTTGGCCTATACTAGCCTTCCCATTGTTTTCACAATGGGCCTTTTATCCCCTCTGAACTGCTTGCCTGCACTTTTATCTT AGACTTTTTTTTTTGATGAGCATAGGTATTTGCTGTGTAAGCCTTATCTAGTGATGCAGAATATCAAGGAGGCCACTTACAATTCTAAGC TGCATCCCTGTATCAAAAATCTCAGAAGCACCTTGCATCTGATAGAGGCTTGTAAGAGCAGATTGACAGGTGAATGTCACAGGTCCATAA GAAGGACAAATAGATCTAAGTTGGGCAAAAGATTCTATTTGTTGGTTCTCCCTTCTAAGATGATAATATGCCCCTGCACTTGAGACCTTA CTTGAAACTTAAAGAAATGTGATTGGTTATGGTGCTGGGAGAAAGGGGTGCACCTGGGAGGACACTGAGAAAGATAAACAAAGGGGAAGG AAGAGAGGACAACCTGTAACTTTTAGAAAAGGCTACTACTTTTAACTGTTGGAGAAAATGCTATTGCTTGCACTCACAATGTCAATATAC ATTATCAGAACTTAAGTCCTGGAGATCAGAGACTGTTTCACCTGAAATTGCTAGCACCTAGAATGGCCCCCGGTTGCGGTAGGCAATCAA TAATACTCTTTGAATAATAATGAGGTTTTCAAAGATTCTGCAAGTCAGACTGGCCTCTGGCTTTGTGATATTATTCTAGAGTCCCAGTAA CCCACAATTGTTGATGAGGAGTAGCAGTAGAATATCAAGGACAGGTGATGAGACAACAAGTCTATCCCGCAAAGGGCAGGGAATAGAGGG TACACTGGAAAGAATTTGAAAACAATAATAAAGCTGACTACAAGTTGGTCTATTTTTTATTACCACCATGAGCCAGCAATTCTAAATAAT ATCAGTGATAAAGTATTCATCCCCCAAAATATTTTATTGAACTAGGTTCTAAACAATTTCTGAGGTTACTGTTGAGTTTTAAATAATACA TATATGTAAGCTTCAAAGTAGCACATTTGTACTGTTTTTCTTCAATAATCATTTTACTCCACATGGAAACTAATTCAGGGAATATCCTGC TATATAGTTGGCTCTCAGTACATATGGTGTCAGCTCATGTGTCTCCAGCCCCTGTAGTACTATATATTATTGCATTTAAATGATGGATTT GAAATAAACAATGATTATACCATGATTGTAAAGACAAGAAACAGAACCTGAAATACTTCAATTTTTGATTCTATGTGGCAGTTTAGAGTT |
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FusionGenePPI for UBE2K_FAM216B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBE2K | DSTYK, HTT, RNF2, UBE2I, DDX58, RNF125, RNF138, BFAR, UBOX5, RNF5, DTX3, MARCH7, SIAH1, TRIM27, RNF185, TRIM35, BIRC7, BIRC8, RNF4, TRIM34, RNF167, UHRF2, TRAF7, MKRN2, TRAIP, RING1, RNF41, MARCH3, RNF32, RNF114, LRSAM1, CBLC, DTX3L, DZIP3, MID1, MKRN3, TRIM39, RNF111, RNF144A, TRIM2, TRIM31, TRIM43, TRIM5, RBCK1, ITSN1, PRPF40A, CCNB1, DIABLO, BRCA1, UBC, CASP12, PIAS4, NUB1, NXF1, FZR1, NEDD4L, WWP2, ITCH, WDR1, WDR61, TXNDC17, TYMS, TXN, ANAPC11, IQCB1, BAG3, UBA1, TP53, MDM2, CDC6, PRRG4, REL, MIPOL1, DDI1, ZDHHC17, AMFR, BARD1, SENP1, MAP3K1, HNRNPA1, UBE2D2, RAB1A, TMEM189-UBE2V1, UBE2V1, UBE2N, RC3H2, TRIM63, SMURF1, CYHR1, ARL15, USP1, DLD | FAM216B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBE2K_FAM216B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBE2K_FAM216B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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