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Fusion gene ID: 40429 |
FusionGeneSummary for UBE2G2_GART |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBE2G2_GART | Fusion gene ID: 40429 | Hgene | Tgene | Gene symbol | UBE2G2 | GART | Gene ID | 7327 | 2618 |
| Gene name | ubiquitin conjugating enzyme E2 G2 | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | |
| Synonyms | UBC7 | AIRS|GARS|GARTF|PAIS|PGFT|PRGS | |
| Cytomap | 21q22.3 | 21q22.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin-conjugating enzyme E2 G2E2 ubiquitin-conjugating enzyme G2ubiquitin carrier protein G2ubiquitin conjugating enzyme 7ubiquitin conjugating enzyme G2ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)ubiquitin-conjugating enzyme E2G 2 ( | trifunctional purine biosynthetic protein adenosine-3GAR transformylaseGARS-AIRS-GARTglycinamide ribonucleotide formyltransferaseglycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P60604 | P22102 | |
| Ensembl transtripts involved in fusion gene | ENST00000345496, ENST00000477954, ENST00000330942, | ENST00000381815, ENST00000381831, ENST00000381839, ENST00000543717, ENST00000361093, ENST00000497313, | |
| Fusion gene scores | * DoF score | 6 X 5 X 5=150 | 4 X 4 X 4=64 |
| # samples | 6 | 4 | |
| ** MAII score | log2(6/150*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UBE2G2 [Title/Abstract] AND GART [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBE2G2 | GO:0044257 | cellular protein catabolic process | 21628527 |
| Hgene | UBE2G2 | GO:0070936 | protein K48-linked ubiquitination | 20061386 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-55-A493-01A | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000345496 | ENST00000381815 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| In-frame | ENST00000345496 | ENST00000381831 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| In-frame | ENST00000345496 | ENST00000381839 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000345496 | ENST00000543717 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000345496 | ENST00000361093 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000345496 | ENST00000497313 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-3CDS | ENST00000477954 | ENST00000381815 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-3CDS | ENST00000477954 | ENST00000381831 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-3CDS | ENST00000477954 | ENST00000381839 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-intron | ENST00000477954 | ENST00000543717 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-intron | ENST00000477954 | ENST00000361093 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5UTR-intron | ENST00000477954 | ENST00000497313 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| Frame-shift | ENST00000330942 | ENST00000381815 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| Frame-shift | ENST00000330942 | ENST00000381831 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| Frame-shift | ENST00000330942 | ENST00000381839 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000330942 | ENST00000543717 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000330942 | ENST00000361093 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
| 5CDS-intron | ENST00000330942 | ENST00000497313 | UBE2G2 | chr21 | 46197214 | - | GART | chr21 | 34897307 | - |
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FusionProtFeatures for UBE2G2_GART |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UBE2G2 | GART |
| Accepts ubiquitin from the E1 complex and catalyzes itscovalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). {ECO:0000269|PubMed:20061386,ECO:0000269|PubMed:22607976}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 434_809 | 355 | 434 | Region | Note=AIRS |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 810_1010 | 355 | 434 | Region | Note=GART |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 818_820 | 355 | 434 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 896_899 | 355 | 434 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 947_951 | 355 | 434 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 977_980 | 355 | 434 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 434_809 | 355 | 1011 | Region | Note=AIRS |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 810_1010 | 355 | 1011 | Region | Note=GART |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 818_820 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 896_899 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 947_951 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 977_980 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 434_809 | 355 | 1011 | Region | Note=AIRS |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 810_1010 | 355 | 1011 | Region | Note=GART |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 818_820 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 896_899 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 947_951 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 977_980 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 434_809 | 355 | 1011 | Region | Note=AIRS |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 810_1010 | 355 | 1011 | Region | Note=GART |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 818_820 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 896_899 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 947_951 | 355 | 1011 | Region | Note=10-formyltetrahydrofolate binding |
| Tgene | >GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 977_980 | 355 | 1011 | Region | Note=5'-phosphoribosylglycinamide binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 111_318 | 355 | 434 | Domain | Note=ATP-grasp |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 111_318 | 355 | 1011 | Domain | Note=ATP-grasp |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 111_318 | 355 | 1011 | Domain | Note=ATP-grasp |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 111_318 | 355 | 1011 | Domain | Note=ATP-grasp |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000361093 | - | 9 | 11 | 137_199 | 355 | 434 | Nucleotide binding | ATP |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381815 | - | 9 | 22 | 137_199 | 355 | 1011 | Nucleotide binding | ATP |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381831 | - | 9 | 22 | 137_199 | 355 | 1011 | Nucleotide binding | ATP |
| Tgene | GART | chr21:46197214 | chr21:34897307 | ENST00000381839 | - | 9 | 22 | 137_199 | 355 | 1011 | Nucleotide binding | ATP |
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FusionGeneSequence for UBE2G2_GART |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381815_chr21_34897307_-_737aa MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNRFPEAQALG LEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKI QPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLD LSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKS SLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSE EEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLI SGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFV QKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASG >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381831_chr21_34897307_-_737aa MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNRFPEAQALG LEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKI QPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLD LSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKS SLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSE EEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLI SGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFV QKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASG >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381839_chr21_34897307_-_737aa MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNRFPEAQALG LEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKI QPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLD LSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKS SLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSE EEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLI SGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFV QKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381815_chr21_34897307_-_2211nt ATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAAT GAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTC CCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGGA CTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGAA AATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCGT GCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAATT CAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTTC AAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCAA GATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGAC CTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAATG CCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAGA ATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATCT TCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCAT TCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCTC CCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGAG GAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCAG CAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAGC ATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAATA TCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAAA GCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATTT GACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGTC CAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAACC GGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAAG AGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGGA >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381831_chr21_34897307_-_2211nt ATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAAT GAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTC CCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGGA CTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGAA AATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCGT GCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAATT CAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTTC AAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCAA GATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGAC CTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAATG CCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAGA ATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATCT TCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCAT TCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCTC CCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGAG GAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCAG CAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAGC ATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAATA TCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAAA GCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATTT GACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGTC CAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAACC GGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAAG AGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGGA >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381839_chr21_34897307_-_2211nt ATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAAT GAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTTC CCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGGA CTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGAA AATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCGT GCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAATT CAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTTC AAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCAA GATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGAC CTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAATG CCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAGA ATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATCT TCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCAT TCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCTC CCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGAG GAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCAG CAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAGC ATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAATA TCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAAA GCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATTT GACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGTC CAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAACC GGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAAG AGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381815_chr21_34897307_-_2675nt ACAAGACCAGGACCCTGAGGCCTCTGGAAGTGCCGGGACCGAACCAACCCCGCAGAGCGACTAAGGCGAGGGCAGGAGCCAAGAGAATCG TAGCCGCGGTCGCGGGTTGAGCTCCCACCACCCGGACAGCGCGCCTCGGCGATCGCGCACGCGCCACGCCCCGGAAGAGTTCCTGGGCCC GCGACGGTGGCCCGGAAGCAGTCCCCGGTGTCGGGGCAGGAGGCACGCGCGCGGCTGAGGCGAGGTCGCTCGGCGCAGCTGTTGCGGGGC CATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAA TGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTT CCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGG ACTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGA AAATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCG TGCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAAT TCAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTT CAAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCA AGATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGA CCTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAAT GCCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAG AATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATC TTCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCA TTCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCT CCCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGA GGAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCA GCAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAG CATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAAT ATCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAA AGCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATT TGACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGT CCAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAAC CGGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAA GAGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGG AACTGTACAGCTTGGAGAAAATGGCAAGATCTGTTGGGTTAAAGAGGAATGAAGCCTTTTAATTCAGAAATGGGGCCAGTTTAGAAAGAA TTATTTGCTGTTTGCATGGTGGTTTTTTATCATGGACTTGGCCCAAAAGAAAAACTGCTAAAAGACAAAAAAGACCTCACCCTTACTTCA >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381831_chr21_34897307_-_2675nt ACAAGACCAGGACCCTGAGGCCTCTGGAAGTGCCGGGACCGAACCAACCCCGCAGAGCGACTAAGGCGAGGGCAGGAGCCAAGAGAATCG TAGCCGCGGTCGCGGGTTGAGCTCCCACCACCCGGACAGCGCGCCTCGGCGATCGCGCACGCGCCACGCCCCGGAAGAGTTCCTGGGCCC GCGACGGTGGCCCGGAAGCAGTCCCCGGTGTCGGGGCAGGAGGCACGCGCGCGGCTGAGGCGAGGTCGCTCGGCGCAGCTGTTGCGGGGC CATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAA TGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTT CCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGG ACTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGA AAATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCG TGCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAAT TCAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTT CAAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCA AGATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGA CCTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAAT GCCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAG AATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATC TTCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCA TTCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCT CCCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGA GGAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCA GCAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAG CATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAAT ATCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAA AGCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATT TGACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGT CCAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAAC CGGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAA GAGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGG AACTGTACAGCTTGGAGAAAATGGCAAGATCTGTTGGGTTAAAGAGGAATGAAGCCTTTTAATTCAGAAATGGGGCCAGTTTAGAAAGAA TTATTTGCTGTTTGCATGGTGGTTTTTTATCATGGACTTGGCCCAAAAGAAAAACTGCTAAAAGACAAAAAAGACCTCACCCTTACTTCA >In-frame_UBE2G2_ENST00000345496_chr21_46197214_-_GART_ENST00000381839_chr21_34897307_-_2675nt ACAAGACCAGGACCCTGAGGCCTCTGGAAGTGCCGGGACCGAACCAACCCCGCAGAGCGACTAAGGCGAGGGCAGGAGCCAAGAGAATCG TAGCCGCGGTCGCGGGTTGAGCTCCCACCACCCGGACAGCGCGCCTCGGCGATCGCGCACGCGCCACGCCCCGGAAGAGTTCCTGGGCCC GCGACGGTGGCCCGGAAGCAGTCCCCGGTGTCGGGGCAGGAGGCACGCGCGCGGCTGAGGCGAGGTCGCTCGGCGCAGCTGTTGCGGGGC CATGGCGGGGACCGCGCTCAAGAGGCTGATGGCCGAGTACAAACAATTAACACTGAATCCTCCGGAAGGAATTGTAGCAGGCCCCATGAA TGAAGAGAACTTTTTTGAATGGGAGGCATTGATCATGGGCCCAGAAGACACCTGCTTTGAGTTTGGTGTTTTTCCTGCCATCCTGAGTTT CCCACTTGATTACCCGTTAAGTCCCCCAAAGATGAGATTTACCTGTGAGATGTTTCATCCCAACAGGTTTCCTGAGGCTCAAGCTCTAGG ACTGGAGGTGTTCCATGCAGGCACTGCCCTCAAAAATGGCAAAGTAGTAACTCATGGGGGTAGAGTTCTTGCAGTCACAGCCATCCGGGA AAATCTCATATCAGCCCTTGAGGAAGCCAAGAAAGGACTAGCTGCTATAAAGTTTGAGGGAGCAATTTATAGGAAAGACGTCGGCTTTCG TGCCATAGCTTTCCTCCAGCAGCCCAGGAGTTTGACTTACAAGGAATCTGGAGTAGATATCGCAGCTGGAAATATGCTGGTCAAGAAAAT TCAGCCTTTAGCAAAAGCCACTTCCAGATCAGGCTGTAAAGTTGATCTTGGAGGTTTTGCTGGTCTTTTTGATTTAAAAGCAGCTGGTTT CAAAGATCCCCTTCTGGCCTCTGGAACAGATGGCGTTGGAACTAAACTAAAGATTGCCCAGCTATGCAATAAACATGATACCATTGGTCA AGATTTGGTAGCAATGTGTGTTAATGATATTCTGGCACAAGGAGCAGAGCCCCTCTTCTTCCTTGATTACTTTTCCTGTGGAAAACTTGA CCTCAGTGTAACTGAAGCTGTTGTTGCTGGAATTGCTAAAGCTTGTGGAAAAGCTGGATGTGCTCTCCTTGGAGGTGAAACAGCAGAAAT GCCTGACATGTATCCCCCTGGAGAGTATGACCTAGCTGGGTTTGCCGTTGGTGCCATGGAGCGAGATCAGAAACTCCCTCACCTGGAAAG AATCACTGAGGGTGATGTTGTTGTTGGAATAGCTTCATCTGGTCTTCATAGCAATGGATTTAGCCTTGTGAGGAAAATCGTGGCAAAATC TTCCCTCCAGTACTCCTCTCCAGCACCTGATGGTTGTGGTGACCAGACTTTAGGGGACTTACTTCTCACGCCTACCAGAATCTACAGCCA TTCACTGTTACCTGTCCTACGTTCAGGACATGTCAAAGCCTTTGCCCATATTACTGGTGGAGGATTACTAGAGAACATCCCCAGAGTCCT CCCTGAGAAACTTGGGGTAGATTTAGATGCCCAGACCTGGAGGATCCCCAGGGTCTTCTCATGGTTGCAGCAGGAAGGACACCTCTCTGA GGAAGAGATGGCCAGAACATTTAACTGTGGGGTTGGCGCTGTCCTTGTGGTATCAAAGGAGCAGACAGAGCAGATTCTGAGGGATATCCA GCAGCACAAGGAAGAAGCCTGGGTGATTGGCAGTGTGGTTGCACGAGCTGAAGGTTCCCCACGTGTGAAAGTCAAGAATCTGATTGAAAG CATGCAAATAAATGGGTCAGTGTTGAAGAATGGCTCCCTGACAAATCATTTCTCTTTTGAAAAAAAAAAGGCCAGAGTGGCTGTCTTAAT ATCTGGAACAGGATCGAACCTGCAAGCACTTATAGACAGTACTCGGGAACCAAATAGCTCTGCACAAATTGATATTGTTATCTCCAACAA AGCCGCAGTAGCTGGGTTAGATAAAGCGGAAAGAGCTGGTATTCCCACTAGAGTAATTAATCATAAACTGTATAAAAATCGTGTAGAATT TGACAGTGCAATTGACCTAGTCCTTGAAGAGTTCTCCATAGACATAGTCTGTCTTGCAGGATTCATGAGAATTCTTTCTGGCCCCTTTGT CCAAAAGTGGAATGGAAAAATGCTCAATATCCACCCATCCTTGCTCCCTTCTTTTAAGGGTTCAAATGCCCATGAGCAAGCCCTGGAAAC CGGAGTCACAGTTACTGGGTGCACTGTACACTTTGTAGCTGAAGATGTGGATGCTGGACAGATTATTTTGCAAGAAGCTGTTCCCGTGAA GAGGGGTGATACTGTCGCAACTCTTTCTGAAAGAGTAAAATTAGCAGAACATAAAATATTTCCTGCAGCCCTTCAGCTGGTGGCCAGTGG AACTGTACAGCTTGGAGAAAATGGCAAGATCTGTTGGGTTAAAGAGGAATGAAGCCTTTTAATTCAGAAATGGGGCCAGTTTAGAAAGAA TTATTTGCTGTTTGCATGGTGGTTTTTTATCATGGACTTGGCCCAAAAGAAAAACTGCTAAAAGACAAAAAAGACCTCACCCTTACTTCA |
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FusionGenePPI for UBE2G2_GART |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| UBE2G2 | AMFR, USP15, AUP1, MALT1, CORO1A, BIRC8, MDM2, MGRN1, RFFL, RNF111, RNF146, RNF157, RNF168, RNF26, TRIM3, TRIM43, ZNRF4, TRIM9, UBC, KIAA0368, PARK2, RNF5, RNF139, RBX1, UBL4A, BAG3, HBS1L, CPOX, MLLT6, NDUFS4, VAMP8, FARP2, POLR3F, KDM2A, CNNM3, ARL14, TMEM45B, UBE2G2, SHFM1, EGFR, UBA1, UBA6, MUL1, ERLEC1, FBXW11, HNRNPAB, HNRNPD, HNRNPDL, TMEM216, RC3H2, RC3H1, OTUB1, DUSP6, PTPRO, TRIM25 | GART | ARF6, ELAVL1, SIRT7, CUL3, CUL5, PAICS, SEPHS1, WARS, FN1, PXN, KPNA2, FBXO6, CARS, FAF1, FARSB, PLOD2, PPAT, SAMHD1, UGP2, XRCC6, HIRIP3, HSPA4, RANBP3, RPL24, SET, SF1, SUPT5H, SWAP70, TROVE2, XPO7, ZYX, CUL7, CCDC8, ADSL, LOC101930400, AKR1C2, ARFIP1, EIF4H, ADSS, ATIC, CCDC108, EEF1A1, KDM3A, NDRG1, TATDN1, HIP1R, HNRNPA1, PFAS, QDPR, RAVER1, STAT6, NTRK1, DBN1, NCBP1, PPIA, DNAJC7, NES, ATL3, MYO19, MCM2, DERL1, INPP5K, COX15, DLD, DLST, SOAT1, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for UBE2G2_GART |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | GART | P22102 | DB00642 | Pemetrexed | Trifunctional purine biosynthetic protein adenosine-3 | small molecule | approved|investigational |
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RelatedDiseases for UBE2G2_GART |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | GART | C0003873 | Rheumatoid Arthritis | 1 | CTD_human |
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