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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 40035

FusionGeneSummary for TTLL5_JDP2

check button Fusion gene summary
Fusion gene informationFusion gene name: TTLL5_JDP2
Fusion gene ID: 40035
HgeneTgene
Gene symbol

TTLL5

JDP2

Gene ID

254173

122953

Gene nametubulin tyrosine ligase like 10Jun dimerization protein 2
SynonymsTTLL5JUNDM2
Cytomap

1p36.33

14q24.3

Type of geneprotein-codingprotein-coding
Descriptioninactive polyglycylase TTLL10tubulin tyrosine ligase-like family, member 10tubulin tyrosine ligase-like family, member 5tubulin--tyrosine ligase-like protein 10jun dimerization protein 2progesterone receptor co-activator
Modification date2018051920180523
UniProtAcc

Q6EMB2

Q8WYK2

Ensembl transtripts involved in fusion geneENST00000557636, ENST00000286650, 
ENST00000298832, ENST00000556893, 
ENST00000554510, ENST00000556977, 
ENST00000555422, 		ENST00000419727, 
ENST00000559773, ENST00000437176, 
ENST00000435893, ENST00000267569, 
Fusion gene scores* DoF score12 X 11 X 10=13203 X 3 X 3=27
# samples 134
** MAII scorelog2(13/1320*10)=-3.34395440121736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TTLL5 [Title/Abstract] AND JDP2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
Transcription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTTLL5

GO:0018094

protein polyglycylation

19524510


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVESCATCGA-L5-A4OQ-01ATTLL5chr14

76259443

+JDP2chr14

75928129

+
TCGARVLIHCTCGA-BC-4073-01BTTLL5chr14

76129566

+JDP2chr14

75904601

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000557636ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000557636ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000557636ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000557636ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000557636ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-3CDSENST00000286650ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000286650ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000286650ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000286650ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000286650ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
In-frameENST00000298832ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000298832ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000298832ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000298832ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000298832ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
In-frameENST00000556893ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000556893ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000556893ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000556893ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000556893ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
In-frameENST00000554510ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000554510ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000554510ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000554510ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-intronENST00000554510ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-3CDSENST00000556977ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000556977ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000556977ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000556977ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000556977ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-3CDSENST00000555422ENST00000419727TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000555422ENST00000559773TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000555422ENST00000437176TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000555422ENST00000435893TTLL5chr14

76259443

+JDP2chr14

75928129

+
intron-intronENST00000555422ENST00000267569TTLL5chr14

76259443

+JDP2chr14

75928129

+
5CDS-5UTRENST00000557636ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-3UTRENST00000557636ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000557636ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000557636ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000557636ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000286650ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-3UTRENST00000286650ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000286650ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000286650ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000286650ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000298832ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-3UTRENST00000298832ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000298832ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000298832ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000298832ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000556893ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-3UTRENST00000556893ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000556893ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000556893ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000556893ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000554510ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-3UTRENST00000554510ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000554510ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000554510ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000554510ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000556977ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-3UTRENST00000556977ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000556977ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000556977ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
5CDS-5UTRENST00000556977ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000555422ENST00000419727TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-3UTRENST00000555422ENST00000559773TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000555422ENST00000437176TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000555422ENST00000435893TTLL5chr14

76129566

+JDP2chr14

75904601

+
intron-5UTRENST00000555422ENST00000267569TTLL5chr14

76129566

+JDP2chr14

75904601

+

Top

FusionProtFeatures for TTLL5_JDP2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TTLL5

Q6EMB2

JDP2

Q8WYK2

Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain initiation step of thepolyglutamylation reaction rather than in the elongation step (Bysimilarity). Required for CCSAP localization to both spindle andcilia microtubules. Increases the effects of NCOA2 inglucocorticoid receptor-mediated repression and induction and inandrogen receptor-mediated induction (PubMed:17116691,PubMed:22493317). {ECO:0000250|UniProtKB:Q8CHB8,ECO:0000269|PubMed:17116691, ECO:0000269|PubMed:22493317}. Component of the AP-1 transcription factor thatrepresses transactivation mediated by the Jun family of proteins.Involved in a variety of transcriptional responses associated withAP-1 such as UV-induced apoptosis, cell differentiation,tumorigenesis and antitumogeneris. Can also function as arepressor by recruiting histone deacetylase 3/HDAC3 to thepromoter region of JUN. May control transcription via directregulation of the modification of histones and the assembly ofchromatin. {ECO:0000269|PubMed:12707301,ECO:0000269|PubMed:12903123, ECO:0000269|PubMed:16026868,ECO:0000269|PubMed:16518400}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732552_55710571282Compositional biasNote=Poly-Arg
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732582_59010571282Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732776_78010571282Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732827_83010571282Compositional biasNote=Poly-Asn
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317552_557608818Compositional biasNote=Poly-Arg
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317582_590608818Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+273262_40710571282DomainTTL
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+131762_407608818DomainTTL
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732208_21110571282Nucleotide bindingATP binding
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317208_211608818Nucleotide bindingATP binding
HgeneTTLL5chr14:76259443chr14:75928129ENST00000298832+2732378_48810571282Regionc-MTBD region
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317378_488608818Regionc-MTBD region
TgeneJDP2chr14:76259443chr14:75928129ENST00000419727+1472_13567164DomainbZIP
TgeneJDP2chr14:76259443chr14:75928129ENST00000435893+1472_13567164DomainbZIP
TgeneJDP2chr14:76259443chr14:75928129ENST00000437176+1472_13567164DomainbZIP
TgeneJDP2chr14:76259443chr14:75928129ENST00000267569+14100_12878175RegionLeucine-zipper
TgeneJDP2chr14:76259443chr14:75928129ENST00000419727+14100_12867164RegionLeucine-zipper
TgeneJDP2chr14:76259443chr14:75928129ENST00000419727+1474_9667164RegionBasic motif
TgeneJDP2chr14:76259443chr14:75928129ENST00000435893+14100_12867164RegionLeucine-zipper
TgeneJDP2chr14:76259443chr14:75928129ENST00000435893+1474_9667164RegionBasic motif
TgeneJDP2chr14:76259443chr14:75928129ENST00000437176+14100_12867164RegionLeucine-zipper
TgeneJDP2chr14:76259443chr14:75928129ENST00000437176+1474_9667164RegionBasic motif

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110552_557-69270Compositional biasNote=Poly-Arg
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110582_590-69270Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110776_780-69270Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110827_830-69270Compositional biasNote=Poly-Asn
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317776_780608818Compositional biasNote=Poly-Glu
HgeneTTLL5chr14:76259443chr14:75928129ENST00000556893+1317827_830608818Compositional biasNote=Poly-Asn
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+11062_407-69270DomainTTL
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110208_211-69270Nucleotide bindingATP binding
HgeneTTLL5chr14:76259443chr14:75928129ENST00000286650+110378_488-69270Regionc-MTBD region
TgeneJDP2chr14:76259443chr14:75928129ENST00000267569+1472_13578175DomainbZIP
TgeneJDP2chr14:76259443chr14:75928129ENST00000267569+1474_9678175RegionBasic motif


Top

FusionGeneSequence for TTLL5_JDP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_TTLL5_ENST00000557636_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_1169aa
MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVH
PSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVK
PVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNY
SVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTL
KPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRPVSAQFQSSKAKQRCRPLSASD
AEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPEL
KIESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQA
KYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAA
KEDEQMELVVRFLKRASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQAS
EAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSS
GPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSF
QSAAHIYSQKLSRPSSAKAAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQLDEEEERR

>In-frame_TTLL5_ENST00000298832_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_1154aa
MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVH
PSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVK
PVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNY
SVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTL
KPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRCRPLSASDAEMKNLVGSAREKG
PGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPELKIESLNSKAKLHAA
LYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKYTPSLTALVENTP
KENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLK
RASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELEEVLTFYTQK
NKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHL
SSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRP
SSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQLDEEEERRKRRREKNKVAAARCR

>In-frame_TTLL5_ENST00000556893_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_705aa
MEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRGNPRRSLLTGRTRMTADGAPELKIESLNSKAKLHA
ALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKYTPSLTALVENT
PKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFL
KRASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELEEVLTFYTQ
KNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTH
LSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSR
PSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQLDEEEERRKRRREKNKVAAARC

>In-frame_TTLL5_ENST00000554510_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_663aa
MNYMLATRLFQDRGNPRRSLLTGRTRMTADGAPELKIESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKT
ETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNL
SKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLKRASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNK
ETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIK
PPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSA
SASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTA
ELQRLAEKQAARQYSPSSHINLLTQQLDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILM


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_TTLL5_ENST00000557636_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_3507nt
ATGCCAATCGTGATGGCCCGGGACCTGGAGGAAACAGCATCATCCTCAGAGGATGAGGAGGTCATAAGTCAAGAGGATCATCCATGCATC
ATGTGGACTGGAGGCTGCAGGAGAATTCCAGTTTTGGTATTCCATGCCGACGCTATTCTTACAAAGGACAACAATATTAGAGTAATTGGA
GAACGTTATCATTTGTCTTATAAGATTGTACGAACGGACAGTCGCCTAGTACGCAGCATTCTGACAGCCCATGGATTTCATGAAGTTCAC
CCAAGCAGCACTGACTATAACCTAATGTGGACAGGATCCCACCTGAAGCCCTTCTTACTGCGCACCCTCTCTGAAGCACAAAAAGTTAAT
CACTTTCCCAGGTCTTATGAACTTACCCGGAAGGACCGACTGTACAAAAACATTATTCGAATGCAGCATACACATGGATTCAAGGCTTTT
CACATCCTCCCCCAGACCTTCCTCCTGCCAGCTGAGTACGCGGAATTTTGTAATTCATATTCGAAGGACCGGGGACCTTGGATAGTAAAA
CCAGTGGCATCTTCAAGGGGGCGGGGCGTCTACCTGATCAACAATCCAAACCAGATCTCCCTGGAAGAGAACATTTTGGTCTCCCGTTAC
ATTAACAACCCCCTGCTCATAGATGATTTCAAGTTTGACGTGCGCCTCTATGTGCTCGTGACTTCCTATGATCCTCTTGTCATCTATCTC
TATGAAGAAGGATTGGCTAGGTTTGCAACTGTGCGATATGATCAAGGAGCCAAGAACATTCGGAACCAGTTCATGCATCTGACAAACTAC
AGTGTCAACAAGAAAAGTGGAGATTACGTCAGTTGTGACGATCCAGAAGTGGAGGATTATGGAAACAAATGGAGCATGAGTGCTATGCTT
AGGTACCTGAAACAAGAAGGCAGAGATACAACCGCATTGATGGCCCATGTAGAAGACCTGATCATTAAGACTATAATCTCTGCTGAACTA
GCTATTGCTACTGCCTGTAAAACCTTTGTTCCTCATCGCAGCAGTTGTTTTGAACTCTATGGCTTTGACGTGCTCATAGATTCTACTCTG
AAGCCATGGTTGTTGGAAGTGAATCTCTCTCCTTCTTTGGCCTGTGATGCGCCTCTGGACCTAAAGATTAAAGCCAGTATGATTTCAGAT
ATGTTCACTGTTGTAGGATTTGTGTGCCAAGATCCTGCCCAGCGGGCATCAACTCGGCCAATTTATCCCACCTTTGAGTCTTCCAGGCGA
AACCCTTTCCAGAAACCTCAGCGTCCAGTATCTGCACAGTTTCAGTCGTCAAAGGCCAAGCAGCGTTGCCGTCCACTCTCTGCCAGTGAT
GCGGAAATGAAAAACCTCGTGGGCTCAGCCCGGGAGAAAGGGCCAGGGAAGTTGGGTGGTTCTGTGCTTGGTCTGTCAATGGAGGAGATC
AAAGTTTTACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCATATTTCCTACATCTGAGACATGGGAAATATATGGG
TCCTACCTCGAGCATAAGACCTCAATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGAATGACTGCTGATGGAGCGCCAGAATTG
AAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCACTTTACGAGAGGAAGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGA
CGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTGATTACCCAACCAGCTGAAATGAATGTTAAAACTGAGACAGAGAGTGAA
GAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAGGAGGCTTCCCAGGAGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCC
AAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCCAAAGAAAATTCCATGAAAGTTCGTGAATGGAATAATAAAGGTGGACAC
TGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAACCTGATGCAGATTCTTCAAGATAATGGCAATCTTAGCAAAATGCAGGCC
CGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGCCTGATGAAAGACAGTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCC
AAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAGCGAGCATCAAATAACCTCCAGCATTCACTGAGGATGGTATTACCCAGT
CGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCACCAGCTGGGTGACTTTATCATTGTATACAACAAGGAAACAGAACAAATG
GCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAAGATGGGGTGAATATGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGT
GAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAGAACAAGTCTGCTAGTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAG
AACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCACCCTGAGACTATAATGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAA
CAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACCACTTCAGCAGAAAAAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCT
GGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTGTCATCTGTTACAACCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCT
TCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCACCAGCCAACAATTTTACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGC
CTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTGCCACGCTGTCGATCAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTC
CAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCCTCTTCAGCAAAGGCAGCAGGATCGTGCTATCTAAACAAGCATCATTCA
GGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATATAGCAAACGGTACAACCAAAGTATGGTTACAGCTGAACTTCAGCGG
CTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCACATCAACCTCCTCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGG
AAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGGAACAAGAAGAAGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAG
CGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAGCTGAAGCAGGAGCGGCAGCAGCTCATCCTGATGCTGAACCGACAC

>In-frame_TTLL5_ENST00000298832_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_3462nt
ATGCCAATCGTGATGGCCCGGGACCTGGAGGAAACAGCATCATCCTCAGAGGATGAGGAGGTCATAAGTCAAGAGGATCATCCATGCATC
ATGTGGACTGGAGGCTGCAGGAGAATTCCAGTTTTGGTATTCCATGCCGACGCTATTCTTACAAAGGACAACAATATTAGAGTAATTGGA
GAACGTTATCATTTGTCTTATAAGATTGTACGAACGGACAGTCGCCTAGTACGCAGCATTCTGACAGCCCATGGATTTCATGAAGTTCAC
CCAAGCAGCACTGACTATAACCTAATGTGGACAGGATCCCACCTGAAGCCCTTCTTACTGCGCACCCTCTCTGAAGCACAAAAAGTTAAT
CACTTTCCCAGGTCTTATGAACTTACCCGGAAGGACCGACTGTACAAAAACATTATTCGAATGCAGCATACACATGGATTCAAGGCTTTT
CACATCCTCCCCCAGACCTTCCTCCTGCCAGCTGAGTACGCGGAATTTTGTAATTCATATTCGAAGGACCGGGGACCTTGGATAGTAAAA
CCAGTGGCATCTTCAAGGGGGCGGGGCGTCTACCTGATCAACAATCCAAACCAGATCTCCCTGGAAGAGAACATTTTGGTCTCCCGTTAC
ATTAACAACCCCCTGCTCATAGATGATTTCAAGTTTGACGTGCGCCTCTATGTGCTCGTGACTTCCTATGATCCTCTTGTCATCTATCTC
TATGAAGAAGGATTGGCTAGGTTTGCAACTGTGCGATATGATCAAGGAGCCAAGAACATTCGGAACCAGTTCATGCATCTGACAAACTAC
AGTGTCAACAAGAAAAGTGGAGATTACGTCAGTTGTGACGATCCAGAAGTGGAGGATTATGGAAACAAATGGAGCATGAGTGCTATGCTT
AGGTACCTGAAACAAGAAGGCAGAGATACAACCGCATTGATGGCCCATGTAGAAGACCTGATCATTAAGACTATAATCTCTGCTGAACTA
GCTATTGCTACTGCCTGTAAAACCTTTGTTCCTCATCGCAGCAGTTGTTTTGAACTCTATGGCTTTGACGTGCTCATAGATTCTACTCTG
AAGCCATGGTTGTTGGAAGTGAATCTCTCTCCTTCTTTGGCCTGTGATGCGCCTCTGGACCTAAAGATTAAAGCCAGTATGATTTCAGAT
ATGTTCACTGTTGTAGGATTTGTGTGCCAAGATCCTGCCCAGCGGGCATCAACTCGGCCAATTTATCCCACCTTTGAGTCTTCCAGGCGA
AACCCTTTCCAGAAACCTCAGCGTTGCCGTCCACTCTCTGCCAGTGATGCGGAAATGAAAAACCTCGTGGGCTCAGCCCGGGAGAAAGGG
CCAGGGAAGTTGGGTGGTTCTGTGCTTGGTCTGTCAATGGAGGAGATCAAAGTTTTACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGT
GGATTTATTCGCATATTTCCTACATCTGAGACATGGGAAATATATGGGTCCTACCTCGAGCATAAGACCTCAATGAACTATATGCTGGCA
ACACGCCTCTTCCAGGACAGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCA
CTTTACGAGAGGAAGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTG
ATTACCCAACCAGCTGAAATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAG
GAGGCTTCCCAGGAGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCC
AAAGAAAATTCCATGAAAGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAAC
CTGATGCAGATTCTTCAAGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGC
CTGATGAAAGACAGTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAG
CGAGCATCAAATAACCTCCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCAC
CAGCTGGGTGACTTTATCATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAA
GATGGGGTGAATATGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAG
AACAAGTCTGCTAGTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCAC
CCTGAGACTATAATGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACC
ACTTCAGCAGAAAAAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTG
TCATCTGTTACAACCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCAC
CAGCCAACAATTTTACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTG
CCACGCTGTCGATCAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCC
TCTTCAGCAAAGGCAGGATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATAT
AGCAAACGGTACAACCAAAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCAC
ATCAACCTCCTCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGG
AACAAGAAGAAGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAG
CTGAAGCAGGAGCGGCAGCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCCGAG

>In-frame_TTLL5_ENST00000556893_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_2115nt
ATGGAGGAGATCAAAGTTTTACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCATATTTCCTACATCTGAGACATGG
GAAATATATGGGTCCTACCTCGAGCATAAGACCTCAATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGGGGAAACCCAAGAAGA
AGCTTATTGACAGGAAGAACACGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCT
GCACTTTACGAGAGGAAGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCA
GTGATTACCCAACCAGCTGAAATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAA
CAGGAGGCTTCCCAGGAGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACA
CCCAAAGAAAATTCCATGAAAGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTT
AACCTGATGCAGATTCTTCAAGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATT
CGCCTGATGAAAGACAGTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTC
AAGCGAGCATCAAATAACCTCCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCC
CACCAGCTGGGTGACTTTATCATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAG
GAAGATGGGGTGAATATGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAA
AAGAACAAGTCTGCTAGTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGAT
CACCCTGAGACTATAATGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTT
ACCACTTCAGCAGAAAAAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCAT
TTGTCATCTGTTACAACCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCT
CACCAGCCAACAATTTTACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGC
CTGCCACGCTGTCGATCAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGT
CCCTCTTCAGCAAAGGCAGGATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTA
TATAGCAAACGGTACAACCAAAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGC
CACATCAACCTCCTCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGC
CGGAACAAGAAGAAGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAG
GAGCTGAAGCAGGAGCGGCAGCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCC

>In-frame_TTLL5_ENST00000554510_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_1989nt
ATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGGGGAAACCCAAGAAGAAGCTTATTGACAGGAAGAACACGAATGACTGCTGAT
GGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCACTTTACGAGAGGAAGCTCCTGTCTCTGGAGGTG
CGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTGATTACCCAACCAGCTGAAATGAATGTTAAAACT
GAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAGGAGGCTTCCCAGGAGGAGTCTGCAGGATTTCTT
AGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCCAAAGAAAATTCCATGAAAGTTCGTGAATGGAAT
AATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAACCTGATGCAGATTCTTCAAGATAATGGCAATCTT
AGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGCCTGATGAAAGACAGTGGCGGTCAGACGTTCAGT
GCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAGCGAGCATCAAATAACCTCCAGCATTCACTGAGG
ATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCACCAGCTGGGTGACTTTATCATTGTATACAACAAG
GAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAAGATGGGGTGAATATGGAAAACTTTCAGGAGTTC
ATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAGAACAAGTCTGCTAGTGTCTTCCTGGGGACTCAC
TCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCACCCTGAGACTATAATGGAAGAAGTGAAAATAAAG
CCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACCACTTCAGCAGAAAAAGAGGCAAAATTAGTTTAT
AGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTGTCATCTGTTACAACCTCTGACCTCTCTCCAGGG
CCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCACCAGCCAACAATTTTACTGAACACAGTCTCTGCC
AGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTGCCACGCTGTCGATCAGGAAGTCACACCATTGGT
CCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCCTCTTCAGCAAAGGCAGGATCGTGCTATCTAAAC
AAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATATAGCAAACGGTACAACCAAAGTATGGTTACAGCT
GAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCACATCAACCTCCTCACCCAACAGCTAGATGAGGAA
GAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGGAACAAGAAGAAGGAGCGCACGGAGTTTCTGCAG
CGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAGCTGAAGCAGGAGCGGCAGCAGCTCATCCTGATG
CTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCCGAGTCAGAAGGCAACCCACTGCTCGAGCAGCTCGAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_TTLL5_ENST00000557636_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_4045nt
GTAGTAACCGGGGAAGCAGCCGTCGGCGGCTGCCCTGAGCCTTCCTGGGGAAGGAGGAGGGAGGTAGGCGCAGAGCGCGGTCCACGCCTG
CTCGCCCCGAACCATGGGAAGATGAGACAGGAATCTGTGCCATCCAAATTGCTTGATCCAGTGAATCTGCTAGGAAAGGTCTCTGAGGCC
CCCGTCTGCTGACTGCATGACAAACCCTAAAGGAAATGCCAATCGTGATGGCCCGGGACCTGGAGGAAACAGCATCATCCTCAGAGGATG
AGGAGGTCATAAGTCAAGAGGATCATCCATGCATCATGTGGACTGGAGGCTGCAGGAGAATTCCAGTTTTGGTATTCCATGCCGACGCTA
TTCTTACAAAGGACAACAATATTAGAGTAATTGGAGAACGTTATCATTTGTCTTATAAGATTGTACGAACGGACAGTCGCCTAGTACGCA
GCATTCTGACAGCCCATGGATTTCATGAAGTTCACCCAAGCAGCACTGACTATAACCTAATGTGGACAGGATCCCACCTGAAGCCCTTCT
TACTGCGCACCCTCTCTGAAGCACAAAAAGTTAATCACTTTCCCAGGTCTTATGAACTTACCCGGAAGGACCGACTGTACAAAAACATTA
TTCGAATGCAGCATACACATGGATTCAAGGCTTTTCACATCCTCCCCCAGACCTTCCTCCTGCCAGCTGAGTACGCGGAATTTTGTAATT
CATATTCGAAGGACCGGGGACCTTGGATAGTAAAACCAGTGGCATCTTCAAGGGGGCGGGGCGTCTACCTGATCAACAATCCAAACCAGA
TCTCCCTGGAAGAGAACATTTTGGTCTCCCGTTACATTAACAACCCCCTGCTCATAGATGATTTCAAGTTTGACGTGCGCCTCTATGTGC
TCGTGACTTCCTATGATCCTCTTGTCATCTATCTCTATGAAGAAGGATTGGCTAGGTTTGCAACTGTGCGATATGATCAAGGAGCCAAGA
ACATTCGGAACCAGTTCATGCATCTGACAAACTACAGTGTCAACAAGAAAAGTGGAGATTACGTCAGTTGTGACGATCCAGAAGTGGAGG
ATTATGGAAACAAATGGAGCATGAGTGCTATGCTTAGGTACCTGAAACAAGAAGGCAGAGATACAACCGCATTGATGGCCCATGTAGAAG
ACCTGATCATTAAGACTATAATCTCTGCTGAACTAGCTATTGCTACTGCCTGTAAAACCTTTGTTCCTCATCGCAGCAGTTGTTTTGAAC
TCTATGGCTTTGACGTGCTCATAGATTCTACTCTGAAGCCATGGTTGTTGGAAGTGAATCTCTCTCCTTCTTTGGCCTGTGATGCGCCTC
TGGACCTAAAGATTAAAGCCAGTATGATTTCAGATATGTTCACTGTTGTAGGATTTGTGTGCCAAGATCCTGCCCAGCGGGCATCAACTC
GGCCAATTTATCCCACCTTTGAGTCTTCCAGGCGAAACCCTTTCCAGAAACCTCAGCGTCCAGTATCTGCACAGTTTCAGTCGTCAAAGG
CCAAGCAGCGTTGCCGTCCACTCTCTGCCAGTGATGCGGAAATGAAAAACCTCGTGGGCTCAGCCCGGGAGAAAGGGCCAGGGAAGTTGG
GTGGTTCTGTGCTTGGTCTGTCAATGGAGGAGATCAAAGTTTTACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCA
TATTTCCTACATCTGAGACATGGGAAATATATGGGTCCTACCTCGAGCATAAGACCTCAATGAACTATATGCTGGCAACACGCCTCTTCC
AGGACAGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCACTTTACGAGAGGA
AGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTGATTACCCAACCAG
CTGAAATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAGGAGGCTTCCCAGG
AGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCCAAAGAAAATTCCA
TGAAAGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAACCTGATGCAGATTC
TTCAAGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGCCTGATGAAAGACA
GTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAGCGAGCATCAAATA
ACCTCCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCACCAGCTGGGTGACT
TTATCATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAAGATGGGGTGAATA
TGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAGAACAAGTCTGCTA
GTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCACCCTGAGACTATAA
TGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACCACTTCAGCAGAAA
AAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTGTCATCTGTTACAA
CCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCACCAGCCAACAATTT
TACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTGCCACGCTGTCGAT
CAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCCTCTTCAGCAAAGG
CAGCAGGATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATATAGCAAACGGT
ACAACCAAAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCACATCAACCTCC
TCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGGAACAAGAAGA
AGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAGCTGAAGCAGG
AGCGGCAGCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCCGAGTCAGAAGGCA
ACCCACTGCTCGAGCAGCTCGAGAAGAAGTGACCATGGGCTGGGAGGAGGTGGAGGAGGAGGAAGAGGAGAAGGAAAAGTGACGAAGAGA
GAGGAGGAGGGGGGCCCCAGATGGCCCTTCCTTTGGTGCATGAAAAACTGTACAATGAGGTTCAGCACAGCCAGCATCAGCCGAGCTTTT
TTGTGAAACTCAGATCAGCCACCCAGGAGGAAGAGCGGGCTGAGGAAACCCAGAGGGACCAAGCGCTGAGACCAAAGTTGACCCTCGGGT

>In-frame_TTLL5_ENST00000298832_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_3990nt
GGGAAGCAGCCGTCGGCGGCTGCCCTGAGCCTTCCTGGGGAAGGAGGAGGGAGGTAGGCGCAGAGCGCGGTCCACGCCTGCTCGCCCCGA
ACCATGGGAAGATGAGACAGGAATCTGTGCCATCCAAATTGCTTGATCCAGTGAATCTGCTAGGAAAGGTCTCTGAGGCCCCCGTCTGCT
GACTGCATGACAAACCCTAAAGGAAATGCCAATCGTGATGGCCCGGGACCTGGAGGAAACAGCATCATCCTCAGAGGATGAGGAGGTCAT
AAGTCAAGAGGATCATCCATGCATCATGTGGACTGGAGGCTGCAGGAGAATTCCAGTTTTGGTATTCCATGCCGACGCTATTCTTACAAA
GGACAACAATATTAGAGTAATTGGAGAACGTTATCATTTGTCTTATAAGATTGTACGAACGGACAGTCGCCTAGTACGCAGCATTCTGAC
AGCCCATGGATTTCATGAAGTTCACCCAAGCAGCACTGACTATAACCTAATGTGGACAGGATCCCACCTGAAGCCCTTCTTACTGCGCAC
CCTCTCTGAAGCACAAAAAGTTAATCACTTTCCCAGGTCTTATGAACTTACCCGGAAGGACCGACTGTACAAAAACATTATTCGAATGCA
GCATACACATGGATTCAAGGCTTTTCACATCCTCCCCCAGACCTTCCTCCTGCCAGCTGAGTACGCGGAATTTTGTAATTCATATTCGAA
GGACCGGGGACCTTGGATAGTAAAACCAGTGGCATCTTCAAGGGGGCGGGGCGTCTACCTGATCAACAATCCAAACCAGATCTCCCTGGA
AGAGAACATTTTGGTCTCCCGTTACATTAACAACCCCCTGCTCATAGATGATTTCAAGTTTGACGTGCGCCTCTATGTGCTCGTGACTTC
CTATGATCCTCTTGTCATCTATCTCTATGAAGAAGGATTGGCTAGGTTTGCAACTGTGCGATATGATCAAGGAGCCAAGAACATTCGGAA
CCAGTTCATGCATCTGACAAACTACAGTGTCAACAAGAAAAGTGGAGATTACGTCAGTTGTGACGATCCAGAAGTGGAGGATTATGGAAA
CAAATGGAGCATGAGTGCTATGCTTAGGTACCTGAAACAAGAAGGCAGAGATACAACCGCATTGATGGCCCATGTAGAAGACCTGATCAT
TAAGACTATAATCTCTGCTGAACTAGCTATTGCTACTGCCTGTAAAACCTTTGTTCCTCATCGCAGCAGTTGTTTTGAACTCTATGGCTT
TGACGTGCTCATAGATTCTACTCTGAAGCCATGGTTGTTGGAAGTGAATCTCTCTCCTTCTTTGGCCTGTGATGCGCCTCTGGACCTAAA
GATTAAAGCCAGTATGATTTCAGATATGTTCACTGTTGTAGGATTTGTGTGCCAAGATCCTGCCCAGCGGGCATCAACTCGGCCAATTTA
TCCCACCTTTGAGTCTTCCAGGCGAAACCCTTTCCAGAAACCTCAGCGTTGCCGTCCACTCTCTGCCAGTGATGCGGAAATGAAAAACCT
CGTGGGCTCAGCCCGGGAGAAAGGGCCAGGGAAGTTGGGTGGTTCTGTGCTTGGTCTGTCAATGGAGGAGATCAAAGTTTTACGAAGGGT
GAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCATATTTCCTACATCTGAGACATGGGAAATATATGGGTCCTACCTCGAGCATAA
GACCTCAATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAA
TTCAAAGGCCAAGCTGCATGCTGCACTTTACGAGAGGAAGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAG
GGCAATGAGGCCAAAATACCCAGTGATTACCCAACCAGCTGAAATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGC
ATTAGATAATGAAGATGAAGAACAGGAGGCTTCCCAGGAGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATT
GACAGCTTTGGTAGAAAATACACCCAAAGAAAATTCCATGAAAGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGAC
TCAGGAGCTAGAGCCTAAATTTAACCTGATGCAGATTCTTCAAGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGC
CTATCTCCAGCATGTTCAAATTCGCCTGATGAAAGACAGTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGAT
GGAGCTGGTTGTTCGTTTCCTCAAGCGAGCATCAAATAACCTCCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCT
GGAACGCAGAAGAATCCTGGCCCACCAGCTGGGTGACTTTATCATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAA
GAAGAAAGTTGAGGAAGAAGAGGAAGATGGGGTGAATATGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGA
GGTGTTGACTTTTTATACCCAAAAGAACAAGTCTGCTAGTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTC
TGATAGTGGGGCAAAAGGTGATCACCCTGAGACTATAATGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCA
TTCTGATAAATTATCTCGATTTACCACTTCAGCAGAAAAAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCT
GCAGAAAATTCCCAACACCCATTTGTCATCTGTTACAACCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCC
TTCAGCTATCCCCAGCATGCCTCACCAGCCAACAATTTTACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACA
GAACATCCCAAGCCCTACTGGCCTGCCACGCTGTCGATCAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACAT
CTATAGCCAGAAACTGTCTCGTCCCTCTTCAGCAAAGGCAGGATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAA
AGAGGGAGAAGATGCTTCTTTATATAGCAAACGGTACAACCAAAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGC
GAGACAGTATTCTCCATCCAGCCACATCAACCTCCTCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAA
CAAAGTCGCAGCAGCCCGATGCCGGAACAAGAAGAAGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGC
AGAGCTGAAGACCCAGATTGAGGAGCTGAAGCAGGAGCGGCAGCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCG
GACCGACAGTGTCAAGACCCCCGAGTCAGAAGGCAACCCACTGCTCGAGCAGCTCGAGAAGAAGTGACCATGGGCTGGGAGGAGGTGGAG
GAGGAGGAAGAGGAGAAGGAAAAGTGACGAAGAGAGAGGAGGAGGGGGGCCCCAGATGGCCCTTCCTTTGGTGCATGAAAAACTGTACAA
TGAGGTTCAGCACAGCCAGCATCAGCCGAGCTTTTTTGTGAAACTCAGATCAGCCACCCAGGAGGAAGAGCGGGCTGAGGAAACCCAGAG
GGACCAAGCGCTGAGACCAAAGTTGACCCTCGGGTAGGGTTGTCCTGCCTGGGGCCCCACTTGAAGGAGGCAGGACAGAGGCACCGAGGC

>In-frame_TTLL5_ENST00000556893_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_2508nt
GAAAAACCTCGTGGGCTCAGCCCGGGAGAAAGGGCCAGGGAAGTTGGGTGGTTCTGTGCTTGGTCTGTCAATGGAGGAGATCAAAGTTTT
ACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCATATTTCCTACATCTGAGACATGGGAAATATATGGGTCCTACCT
CGAGCATAAGACCTCAATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGGGGAAACCCAAGAAGAAGCTTATTGACAGGAAGAAC
ACGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCACTTTACGAGAGGAAGCT
CCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTGATTACCCAACCAGCTGA
AATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAGGAGGCTTCCCAGGAGGA
GTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCCAAAGAAAATTCCATGAA
AGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAACCTGATGCAGATTCTTCA
AGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGCCTGATGAAAGACAGTGG
CGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAGCGAGCATCAAATAACCT
CCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCACCAGCTGGGTGACTTTAT
CATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAAGATGGGGTGAATATGGA
AAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAGAACAAGTCTGCTAGTGT
CTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCACCCTGAGACTATAATGGA
AGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACCACTTCAGCAGAAAAAGA
GGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTGTCATCTGTTACAACCTC
TGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCACCAGCCAACAATTTTACT
GAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTGCCACGCTGTCGATCAGG
AAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCCTCTTCAGCAAAGGCAGG
ATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATATAGCAAACGGTACAACCA
AAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCACATCAACCTCCTCACCCA
ACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGGAACAAGAAGAAGGAGCG
CACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAGCTGAAGCAGGAGCGGCA
GCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCCGAGTCAGAAGGCAACCCACT
GCTCGAGCAGCTCGAGAAGAAGTGACCATGGGCTGGGAGGAGGTGGAGGAGGAGGAAGAGGAGAAGGAAAAGTGACGAAGAGAGAGGAGG
AGGGGGGCCCCAGATGGCCCTTCCTTTGGTGCATGAAAAACTGTACAATGAGGTTCAGCACAGCCAGCATCAGCCGAGCTTTTTTGTGAA
ACTCAGATCAGCCACCCAGGAGGAAGAGCGGGCTGAGGAAACCCAGAGGGACCAAGCGCTGAGACCAAAGTTGACCCTCGGGTAGGGTTG

>In-frame_TTLL5_ENST00000554510_chr14_76259443_+_JDP2_ENST00000419727_chr14_75928129_+_2431nt
AGATCAAAGTTTTACGAAGGGTGAAGGAGGAGAATGATCGGCGAGGTGGATTTATTCGCATATTTCCTACATCTGAGACATGGGAAATAT
ATGGGTCCTACCTCGAGCATAAGACCTCAATGAACTATATGCTGGCAACACGCCTCTTCCAGGACAGGGGAAACCCAAGAAGAAGCTTAT
TGACAGGAAGAACACGAATGACTGCTGATGGAGCGCCAGAATTGAAGATAGAGAGTCTGAATTCAAAGGCCAAGCTGCATGCTGCACTTT
ACGAGAGGAAGCTCCTGTCTCTGGAGGTGCGAAAACGTAGACGACGGAGTAGCAGATTGAGGGCAATGAGGCCAAAATACCCAGTGATTA
CCCAACCAGCTGAAATGAATGTTAAAACTGAGACAGAGAGTGAAGAGGAGGAAGAAGTCGCATTAGATAATGAAGATGAAGAACAGGAGG
CTTCCCAGGAGGAGTCTGCAGGATTTCTTAGAGAAAATCAAGCCAAATATACACCCTCATTGACAGCTTTGGTAGAAAATACACCCAAAG
AAAATTCCATGAAAGTTCGTGAATGGAATAATAAAGGTGGACACTGCTGCAAACTTGAGACTCAGGAGCTAGAGCCTAAATTTAACCTGA
TGCAGATTCTTCAAGATAATGGCAATCTTAGCAAAATGCAGGCCCGAATAGCATTCTCTGCCTATCTCCAGCATGTTCAAATTCGCCTGA
TGAAAGACAGTGGCGGTCAGACGTTCAGTGCCAGTTGGGCTGCCAAAGAGGATGAACAGATGGAGCTGGTTGTTCGTTTCCTCAAGCGAG
CATCAAATAACCTCCAGCATTCACTGAGGATGGTATTACCCAGTCGACGATTGGCACTTCTGGAACGCAGAAGAATCCTGGCCCACCAGC
TGGGTGACTTTATCATTGTATACAACAAGGAAACAGAACAAATGGCTGAAAAGAAATCAAAGAAGAAAGTTGAGGAAGAAGAGGAAGATG
GGGTGAATATGGAAAACTTTCAGGAGTTCATCAGACAAGCAAGTGAGGCTGAACTGGAGGAGGTGTTGACTTTTTATACCCAAAAGAACA
AGTCTGCTAGTGTCTTCCTGGGGACTCACTCTAAAATTTCTAAGAACAACAACAATTATTCTGATAGTGGGGCAAAAGGTGATCACCCTG
AGACTATAATGGAAGAAGTGAAAATAAAGCCACCTAAACAGCAACAGACGACAGAAATTCATTCTGATAAATTATCTCGATTTACCACTT
CAGCAGAAAAAGAGGCAAAATTAGTTTATAGCAATTCCTCCTCTGGTCCTACTGCTACTCTGCAGAAAATTCCCAACACCCATTTGTCAT
CTGTTACAACCTCTGACCTCTCTCCAGGGCCTTGCCACCATTCTTCTTTATCTCAAATTCCTTCAGCTATCCCCAGCATGCCTCACCAGC
CAACAATTTTACTGAACACAGTCTCTGCCAGTGCTTCTCCCTGCCTACATCCCGGGGCACAGAACATCCCAAGCCCTACTGGCCTGCCAC
GCTGTCGATCAGGAAGTCACACCATTGGTCCCTTTTCTTCCTTCCAAAGTGCTGCACACATCTATAGCCAGAAACTGTCTCGTCCCTCTT
CAGCAAAGGCAGGATCGTGCTATCTAAACAAGCATCATTCAGGAATAGCCAAAACACAAAAAGAGGGAGAAGATGCTTCTTTATATAGCA
AACGGTACAACCAAAGTATGGTTACAGCTGAACTTCAGCGGCTAGCTGAGAAGCAGGCAGCGAGACAGTATTCTCCATCCAGCCACATCA
ACCTCCTCACCCAACAGCTAGATGAGGAAGAGGAGCGAAGGAAAAGGCGCCGGGAGAAGAACAAAGTCGCAGCAGCCCGATGCCGGAACA
AGAAGAAGGAGCGCACGGAGTTTCTGCAGCGGGAATCCGAGCGGCTGGAACTCATGAACGCAGAGCTGAAGACCCAGATTGAGGAGCTGA
AGCAGGAGCGGCAGCAGCTCATCCTGATGCTGAACCGACACCGCCCCACCTGCATCGTCCGGACCGACAGTGTCAAGACCCCCGAGTCAG
AAGGCAACCCACTGCTCGAGCAGCTCGAGAAGAAGTGACCATGGGCTGGGAGGAGGTGGAGGAGGAGGAAGAGGAGAAGGAAAAGTGACG
AAGAGAGAGGAGGAGGGGGGCCCCAGATGGCCCTTCCTTTGGTGCATGAAAAACTGTACAATGAGGTTCAGCACAGCCAGCATCAGCCGA
GCTTTTTTGTGAAACTCAGATCAGCCACCCAGGAGGAAGAGCGGGCTGAGGAAACCCAGAGGGACCAAGCGCTGAGACCAAAGTTGACCC
TCGGGTAGGGTTGTCCTGCCTGGGGCCCCACTTGAAGGAGGCAGGACAGAGGCACCGAGGCCAGGGAGACGCCCAACGAGGCAGCCCTGG


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FusionGenePPI for TTLL5_JDP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
TTLL5TP53, TP73, CREB3, THBS3, MED4, PCM1, CEP128, OFD1, PTTG1, CEP135, FGFR1OP, GAR1, CCDC14, VWCE, TTC25, CACNG5JDP2IRF2BP1, ATF7, JUND, JUN, ATF2, GTF2H1, JDP2, PGR, ELAVL1, HDAC6, HDAC10, HDAC1, HDAC4, HDAC5, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for TTLL5_JDP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TTLL5_JDP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTTLL5C3495559Juvenile arthritis1CTD_human
HgeneTTLL5C4014501CONE-ROD DYSTROPHY 191UNIPROT
TgeneJDP2C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneJDP2C2239176Liver carcinoma1CTD_human