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Fusion gene ID: 40020 |
FusionGeneSummary for TTLL10_CTAG2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TTLL10_CTAG2 | Fusion gene ID: 40020 | Hgene | Tgene | Gene symbol | TTLL10 | CTAG2 | Gene ID | 254173 | 30848 |
| Gene name | tubulin tyrosine ligase like 10 | cancer/testis antigen 2 | |
| Synonyms | TTLL5 | CAMEL|CT2|CT6.2|CT6.2a|CT6.2b|ESO2|LAGE-1|LAGE2B | |
| Cytomap | 1p36.33 | Xq28 | |
| Type of gene | protein-coding | protein-coding | |
| Description | inactive polyglycylase TTLL10tubulin tyrosine ligase-like family, member 10tubulin tyrosine ligase-like family, member 5tubulin--tyrosine ligase-like protein 10 | cancer/testis antigen 2CTL-recognized antigen on melanomaLAGE-1a proteinautoimmunogenic cancer/testis antigen NY-ESO-2cancer/testis antigen 6.2cancer/testis antigen family 6, member 2acancer/testis antigen family 6, member 2bl antigen family member | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q6ZVT0 | O75638 | |
| Ensembl transtripts involved in fusion gene | ENST00000506177, ENST00000379290, ENST00000379289, ENST00000379288, | ENST00000247306, ENST00000369585, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: TTLL10 [Title/Abstract] AND CTAG2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TTLL10 | GO:0018094 | protein polyglycylation | 19524510 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | CESC | TCGA-Q1-A73P-01A | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000506177 | ENST00000247306 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| intron-3CDS | ENST00000506177 | ENST00000369585 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| Frame-shift | ENST00000379290 | ENST00000247306 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| In-frame | ENST00000379290 | ENST00000369585 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| Frame-shift | ENST00000379289 | ENST00000247306 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| In-frame | ENST00000379289 | ENST00000369585 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| In-frame | ENST00000379288 | ENST00000247306 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
| Frame-shift | ENST00000379288 | ENST00000369585 | TTLL10 | chr1 | 1120489 | + | CTAG2 | chrX | 153880541 | - |
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FusionProtFeatures for TTLL10_CTAG2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TTLL10 | CTAG2 |
| Inactive polyglycylase. {ECO:0000269|PubMed:19524510}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for TTLL10_CTAG2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TTLL10_ENST00000379290_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_513aa MDHSCTRFIHRRGPPTRTRAGFKRGKRPRIQQRPRARVSGTIPASRLHPAPASQPGPCPAPGHCPVGPAHERPMGSSQEEGLRCQPSQPD HDADGHCGPDLEGAERASATPGPPGLLNSHRPADSDDTNAAGPSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQ RIHDSRRDDYTLKWCEVKSRDSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGVQARLEKDAAAPALEDLPWTSP GYLRPQRVLRMEEFFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARV VQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGHGYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDT >In-frame_TTLL10_ENST00000379289_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_513aa MDHSCTRFIHRRGPPTRTRAGFKRGKRPRIQQRPRARVSGTIPASRLHPAPASQPGPCPAPGHCPVGPAHERPMGSSQEEGLRCQPSQPD HDADGHCGPDLEGAERASATPGPPGLLNSHRPADSDDTNAAGPSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQ RIHDSRRDDYTLKWCEVKSRDSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGVQARLEKDAAAPALEDLPWTSP GYLRPQRVLRMEEFFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARV VQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGHGYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDT >In-frame_TTLL10_ENST00000379288_chr1_1120489_+_CTAG2_ENST00000247306_chrX_153880541_-_645aa MGSSQEEGLRCQPSQPDHDADGHCGPDLEGAERASATPGPPGLLNSHRPADSDDTNAAGPSAALLEGLLLGGGKPSPHSTRPGPFFYIGG SNGATIISSYCKSKGWQRIHDSRRDDYTLKWCEVKSRDSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGVQARL EKDAAAPALEDLPWTSPGYLRPQRVLRMEEFFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSME DDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGHGYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLK EHTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKVRPLCPPVWEXDPSGRGCVVRLGTRHTDVRGVRGRLRXSVTXPCGTKPFQRLCSLS WQCLSPAASKGPDGKPSRGSVGTSPAGSLAVGSGDSSASVTATMXRVFVPFRSSTWQAGPTAAPGPGVLEQQQLPVQARTLPSXGPCAVE CPNFAGFLSVGVPVGYFKQPXQQRPLSSAVXNWDKNGAWPKDFYLSWSPRPGPGSSSQGWSFLTHRRVSLWLGRQRSEEPPVTFLTSPKL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TTLL10_ENST00000379290_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_1540nt ATGGACCACAGCTGCACCCGGTTCATCCACCGCCGGGGACCACCCACTCGGACCCGAGCCGGCTTCAAGAGGGGCAAGAGGCCAAGGATC CAGCAGAGGCCTCGGGCTCGAGTCTCAGGGACCATCCCTGCGTCACGTCTGCACCCAGCACCGGCCTCACAGCCCGGCCCCTGCCCTGCA CCAGGCCACTGCCCTGTTGGCCCGGCCCACGAGAGGCCAATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAGAC CACGACGCAGATGGACACTGTGGGCCGGACCTGGAGGGGGCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCCAC CGGCCTGCAGACTCGGATGACACTAACGCCGCCGGGCCCTCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGCCC CACAGCACCCGGCCGGGGCCCTTCTTCTACATTGGAGGCAGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGCAG CGCATCCATGACAGCCGCCGGGACGACTACACGCTGAAGTGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAGAG CAGCTGCTGTACCAGCTTCCCAACAACAAGCTCCTCACCACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGAGC AAGGCCAGCAAGGTGCCGGGGGGGGTCCAGGCCAGGCTGGAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCCCA GGATACCTCAGGCCACAGAGGGTCCTGAGAATGGAAGAGTTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCTTT TTCACCTTGTTTGATGAAACCCAGATATGGATCTGCAAGCCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGGAG GAAGTTGCCGCCCTGCAGGCCAAGACCCGGAGCATGGAGGACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGGTG GTGCAGAGGTACATCCAGAACCCGCTGCTGGTGGACGGGAGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCTAC ATGATCTTCTTTGGCCACGGCTATGCTCGCCTCACCCTTAGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACCAG TTCATGCAGAAGAAGAGCCCTCTGTACATGCTGCTGAAGGAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACACG TTCTGGAAGGCCCGGGGCCTCGCCAAGGACTGGGTCTTCACCACCCTCAAGCCGACTGACTGCTGCAGACCACCGCCAACTGCAGCTCTC CATCAGCTCCTGTCTCCAGCAGCTTTCCCTGTTGATGTGGATCACGCAGTGCTTTCTGCCCGTGTTTTTGGCTCAGGCTCCCTCAGGGCA >In-frame_TTLL10_ENST00000379289_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_1540nt ATGGACCACAGCTGCACCCGGTTCATCCACCGCCGGGGACCACCCACTCGGACCCGAGCCGGCTTCAAGAGGGGCAAGAGGCCAAGGATC CAGCAGAGGCCTCGGGCTCGAGTCTCAGGGACCATCCCTGCGTCACGTCTGCACCCAGCACCGGCCTCACAGCCCGGCCCCTGCCCTGCA CCAGGCCACTGCCCTGTTGGCCCGGCCCACGAGAGGCCAATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAGAC CACGACGCAGATGGACACTGTGGGCCGGACCTGGAGGGGGCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCCAC CGGCCTGCAGACTCGGATGACACTAACGCCGCCGGGCCCTCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGCCC CACAGCACCCGGCCGGGGCCCTTCTTCTACATTGGAGGCAGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGCAG CGCATCCATGACAGCCGCCGGGACGACTACACGCTGAAGTGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAGAG CAGCTGCTGTACCAGCTTCCCAACAACAAGCTCCTCACCACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGAGC AAGGCCAGCAAGGTGCCGGGGGGGGTCCAGGCCAGGCTGGAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCCCA GGATACCTCAGGCCACAGAGGGTCCTGAGAATGGAAGAGTTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCTTT TTCACCTTGTTTGATGAAACCCAGATATGGATCTGCAAGCCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGGAG GAAGTTGCCGCCCTGCAGGCCAAGACCCGGAGCATGGAGGACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGGTG GTGCAGAGGTACATCCAGAACCCGCTGCTGGTGGACGGGAGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCTAC ATGATCTTCTTTGGCCACGGCTATGCTCGCCTCACCCTTAGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACCAG TTCATGCAGAAGAAGAGCCCTCTGTACATGCTGCTGAAGGAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACACG TTCTGGAAGGCCCGGGGCCTCGCCAAGGACTGGGTCTTCACCACCCTCAAGCCGACTGACTGCTGCAGACCACCGCCAACTGCAGCTCTC CATCAGCTCCTGTCTCCAGCAGCTTTCCCTGTTGATGTGGATCACGCAGTGCTTTCTGCCCGTGTTTTTGGCTCAGGCTCCCTCAGGGCA >In-frame_TTLL10_ENST00000379288_chr1_1120489_+_CTAG2_ENST00000247306_chrX_153880541_-_1937nt ATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAGACCACGACGCAGATGGACACTGTGGGCCGGACCTGGAGGGG GCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCCACCGGCCTGCAGACTCGGATGACACTAACGCCGCCGGGCCC TCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGCCCCACAGCACCCGGCCGGGGCCCTTCTTCTACATTGGAGGC AGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGCAGCGCATCCATGACAGCCGCCGGGACGACTACACGCTGAAG TGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAGAGCAGCTGCTGTACCAGCTTCCCAACAACAAGCTCCTCACC ACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGAGCAAGGCCAGCAAGGTGCCGGGGGGGGTCCAGGCCAGGCTG GAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCCCAGGATACCTCAGGCCACAGAGGGTCCTGAGAATGGAAGAG TTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCTTTTTCACCTTGTTTGATGAAACCCAGATATGGATCTGCAAG CCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGGAGGAAGTTGCCGCCCTGCAGGCCAAGACCCGGAGCATGGAG GACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGGTGGTGCAGAGGTACATCCAGAACCCGCTGCTGGTGGACGGG AGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCTACATGATCTTCTTTGGCCACGGCTATGCTCGCCTCACCCTT AGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACCAGTTCATGCAGAAGAAGAGCCCTCTGTACATGCTGCTGAAG GAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACACGTTCTGGAAGGCCCGGGGCCTCGCCAAGGACTGGGTCTTC ACCACCCTCAAGGTGCGTCCACTGTGCCCTCCAGTCTGGGAGTGAGATCCCTCGGGGCGGGGGTGTGTGGTCAGGCTGGGCACCAGGCAC ACAGATGTCCGTGGCGTGCGTGGGCGGCTGCGCTGAAGTGTGACCTGACCGTGTGGAACCAAACCCTTCCAGCGTCTCTGCTCACTTAGC TGGCAGTGCCTGTCCCCAGCAGCCAGCAAAGGCCCGGACGGAAAGCCCAGTCGGGGGTCTGTCGGCACGAGTCCCGCGGGCAGCCTCGCC GTAGGGTCAGGGGACAGCTCGGCTTCAGTGACAGCCACCATGTGAAGAGTCTTTGTTCCTTTCAGATCCTCCACTTGGCAGGCAGGGCCA ACAGCAGCCCCCGGGCCAGGTGTCCTGGAGCAGCAGCAGCTGCCCGTGCAGGCCCGGACTCTCCCTAGCTAAGGGCCATGTGCGGTGGAG TGTCCTAATTTTGCAGGGTTCCTTTCTGTGGGGGTACCTGTGGGGTACTTCAAACAGCCCTAGCAGCAAAGGCCCTTGAGCAGCGCGGTG TGAAACTGGGATAAAAACGGGGCTTGGCCGAAGGACTTTTATCTGTCTTGGTCACCCCGGCCAGGCCCCGGAAGCAGCAGCCAGGGATGG TCCTTCCTCACCCACAGGCGTGTGTCACTGTGGCTGGGACGGCAGCGCTCAGAGGAGCCTCCAGTTACTTTCCTCACATCTCCCAAACTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TTLL10_ENST00000379290_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_1865nt CCCAGGACCTTGTGGGCTGGGCAGGTCGTGCGTCCTTTGACAGCGGCCTCCGGCCGGGAGGCACCAGCTCTTCGAACAATGTTTAAAAGT CTCTTCTGTTCATCCTACCGGGGTGCCGTCTCCTGCCGGTCTTTTCATCTCACCAGGGCCCTCGCCCGGGCACCCCCCGGCCAATGGACC ACAGCTGCACCCGGTTCATCCACCGCCGGGGACCACCCACTCGGACCCGAGCCGGCTTCAAGAGGGGCAAGAGGCCAAGGATCCAGCAGA GGCCTCGGGCTCGAGTCTCAGGGACCATCCCTGCGTCACGTCTGCACCCAGCACCGGCCTCACAGCCCGGCCCCTGCCCTGCACCAGGCC ACTGCCCTGTTGGCCCGGCCCACGAGAGGCCAATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAGACCACGACG CAGATGGACACTGTGGGCCGGACCTGGAGGGGGCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCCACCGGCCTG CAGACTCGGATGACACTAACGCCGCCGGGCCCTCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGCCCCACAGCA CCCGGCCGGGGCCCTTCTTCTACATTGGAGGCAGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGCAGCGCATCC ATGACAGCCGCCGGGACGACTACACGCTGAAGTGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAGAGCAGCTGC TGTACCAGCTTCCCAACAACAAGCTCCTCACCACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGAGCAAGGCCA GCAAGGTGCCGGGGGGGGTCCAGGCCAGGCTGGAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCCCAGGATACC TCAGGCCACAGAGGGTCCTGAGAATGGAAGAGTTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCTTTTTCACCT TGTTTGATGAAACCCAGATATGGATCTGCAAGCCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGGAGGAAGTTG CCGCCCTGCAGGCCAAGACCCGGAGCATGGAGGACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGGTGGTGCAGA GGTACATCCAGAACCCGCTGCTGGTGGACGGGAGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCTACATGATCT TCTTTGGCCACGGCTATGCTCGCCTCACCCTTAGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACCAGTTCATGC AGAAGAAGAGCCCTCTGTACATGCTGCTGAAGGAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACACGTTCTGGA AGGCCCGGGGCCTCGCCAAGGACTGGGTCTTCACCACCCTCAAGCCGACTGACTGCTGCAGACCACCGCCAACTGCAGCTCTCCATCAGC TCCTGTCTCCAGCAGCTTTCCCTGTTGATGTGGATCACGCAGTGCTTTCTGCCCGTGTTTTTGGCTCAGGCTCCCTCAGGGCAGAGGCGC TAAGCCCAGCCTGGCGCCCCTTCCTAGGTCATGCCTCCTCCCCTAGGGAATGGTCCCAGCACGAGTGGCCAGTTCATTGTGGGGGCCTGA >In-frame_TTLL10_ENST00000379289_chr1_1120489_+_CTAG2_ENST00000369585_chrX_153880541_-_1843nt AGGACCTTGTGGGCTGGGCAGCGGCCTCCGGCCGGGAGGCACCAGCTCTTCGAACAATGTTTAAAAGTCTCTTCTGTTCATCCTACCGGG GTGCCGTCTCCTGCCGGTCTTTTCATCTCACCAGGGCCCTCGCCCGGGCACCCCCCGGCCAATGGACCACAGCTGCACCCGGTTCATCCA CCGCCGGGGACCACCCACTCGGACCCGAGCCGGCTTCAAGAGGGGCAAGAGGCCAAGGATCCAGCAGAGGCCTCGGGCTCGAGTCTCAGG GACCATCCCTGCGTCACGTCTGCACCCAGCACCGGCCTCACAGCCCGGCCCCTGCCCTGCACCAGGCCACTGCCCTGTTGGCCCGGCCCA CGAGAGGCCAATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAGACCACGACGCAGATGGACACTGTGGGCCGGA CCTGGAGGGGGCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCCACCGGCCTGCAGACTCGGATGACACTAACGC CGCCGGGCCCTCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGCCCCACAGCACCCGGCCGGGGCCCTTCTTCTA CATTGGAGGCAGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGCAGCGCATCCATGACAGCCGCCGGGACGACTA CACGCTGAAGTGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAGAGCAGCTGCTGTACCAGCTTCCCAACAACAA GCTCCTCACCACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGAGCAAGGCCAGCAAGGTGCCGGGGGGGGTCCA GGCCAGGCTGGAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCCCAGGATACCTCAGGCCACAGAGGGTCCTGAG AATGGAAGAGTTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCTTTTTCACCTTGTTTGATGAAACCCAGATATG GATCTGCAAGCCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGGAGGAAGTTGCCGCCCTGCAGGCCAAGACCCG GAGCATGGAGGACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGGTGGTGCAGAGGTACATCCAGAACCCGCTGCT GGTGGACGGGAGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCTACATGATCTTCTTTGGCCACGGCTATGCTCG CCTCACCCTTAGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACCAGTTCATGCAGAAGAAGAGCCCTCTGTACAT GCTGCTGAAGGAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACACGTTCTGGAAGGCCCGGGGCCTCGCCAAGGA CTGGGTCTTCACCACCCTCAAGCCGACTGACTGCTGCAGACCACCGCCAACTGCAGCTCTCCATCAGCTCCTGTCTCCAGCAGCTTTCCC TGTTGATGTGGATCACGCAGTGCTTTCTGCCCGTGTTTTTGGCTCAGGCTCCCTCAGGGCAGAGGCGCTAAGCCCAGCCTGGCGCCCCTT CCTAGGTCATGCCTCCTCCCCTAGGGAATGGTCCCAGCACGAGTGGCCAGTTCATTGTGGGGGCCTGATTGTTTGTCGCTGGAGGAGGAC >In-frame_TTLL10_ENST00000379288_chr1_1120489_+_CTAG2_ENST00000247306_chrX_153880541_-_3290nt AGGACCTTGTGGGCTGGGCAGGCCCGGCCCACGAGAGGCCAATGGGGAGCAGCCAGGAGGAGGGACTCCGGTGTCAGCCAAGCCAGCCAG ACCACGACGCAGATGGACACTGTGGGCCGGACCTGGAGGGGGCAGAAAGAGCCTCTGCCACACCCGGACCCCCTGGGCTCCTGAACAGCC ACCGGCCTGCAGACTCGGATGACACTAACGCCGCCGGGCCCTCAGCTGCCCTCCTGGAGGGGCTCCTGCTGGGGGGTGGGAAGCCATCGC CCCACAGCACCCGGCCGGGGCCCTTCTTCTACATTGGAGGCAGCAACGGGGCCACAATCATCAGCTCCTACTGCAAAAGCAAGGGCTGGC AGCGCATCCATGACAGCCGCCGGGACGACTACACGCTGAAGTGGTGTGAGGTCAAGAGCCGAGACAGCTACGGCAGCTTCCGGGAAGGAG AGCAGCTGCTGTACCAGCTTCCCAACAACAAGCTCCTCACCACCAAGATCGGGCTGCTCAGCACCCTTCGGGGACGGGCACGGGCCATGA GCAAGGCCAGCAAGGTGCCGGGGGGGGTCCAGGCCAGGCTGGAAAAGGACGCAGCAGCGCCCGCCCTGGAGGACCTCCCGTGGACAAGCC CAGGATACCTCAGGCCACAGAGGGTCCTGAGAATGGAAGAGTTTTTCCCAGAGACCTACCGCCTGGACCTCAAACACGAGAGAGAGGCCT TTTTCACCTTGTTTGATGAAACCCAGATATGGATCTGCAAGCCCACAGCCTCCAACCAGGGCAAAGGCATCTTCCTGCTCCGGAACCAGG AGGAAGTTGCCGCCCTGCAGGCCAAGACCCGGAGCATGGAGGACGACCCCATCCACCACAAGACGCCGTTCCGGGGGCCTCAGGCGCGGG TGGTGCAGAGGTACATCCAGAACCCGCTGCTGGTGGACGGGAGAAAGTTTGACGTGCGCTCCTACCTGCTCATTGCCTGCACCACACCCT ACATGATCTTCTTTGGCCACGGCTATGCTCGCCTCACCCTTAGCCTTTACGACCCCCATTCCAGCGACCTCGGCGGCCACTTGACCAACC AGTTCATGCAGAAGAAGAGCCCTCTGTACATGCTGCTGAAGGAGCACACGGTGTGGAGCATGGAACACCTCAACCGCTACATCAGTGACA CGTTCTGGAAGGCCCGGGGCCTCGCCAAGGACTGGGTCTTCACCACCCTCAAGGTGCGTCCACTGTGCCCTCCAGTCTGGGAGTGAGATC CCTCGGGGCGGGGGTGTGTGGTCAGGCTGGGCACCAGGCACACAGATGTCCGTGGCGTGCGTGGGCGGCTGCGCTGAAGTGTGACCTGAC CGTGTGGAACCAAACCCTTCCAGCGTCTCTGCTCACTTAGCTGGCAGTGCCTGTCCCCAGCAGCCAGCAAAGGCCCGGACGGAAAGCCCA GTCGGGGGTCTGTCGGCACGAGTCCCGCGGGCAGCCTCGCCGTAGGGTCAGGGGACAGCTCGGCTTCAGTGACAGCCACCATGTGAAGAG TCTTTGTTCCTTTCAGATCCTCCACTTGGCAGGCAGGGCCAACAGCAGCCCCCGGGCCAGGTGTCCTGGAGCAGCAGCAGCTGCCCGTGC AGGCCCGGACTCTCCCTAGCTAAGGGCCATGTGCGGTGGAGTGTCCTAATTTTGCAGGGTTCCTTTCTGTGGGGGTACCTGTGGGGTACT TCAAACAGCCCTAGCAGCAAAGGCCCTTGAGCAGCGCGGTGTGAAACTGGGATAAAAACGGGGCTTGGCCGAAGGACTTTTATCTGTCTT GGTCACCCCGGCCAGGCCCCGGAAGCAGCAGCCAGGGATGGTCCTTCCTCACCCACAGGCGTGTGTCACTGTGGCTGGGACGGCAGCGCT CAGAGGAGCCTCCAGTTACTTTCCTCACATCTCCCAAACTCTCTCTTAATTGCGATAATTCACAGAACATAAAATTCACGATCTTAAATC TGCCTCCGCATCCTCGTGGGCCCTGACCTTCTCTCTGAGAGCCGGGCAGAGGCTCCGGAGCCATGCAGGCCGAAGGCCAGGGCACAGGGG GTTCGACGGGCGATGCTGATGGCCCAGGAGGCCCTGGCATTCCTGATGGCCCAGGGGGCAATGCTGGCGGCCCAGGAGAGGCGGGTGCCA CGGGCGGCAGAGGTCCCCGGGGCGCAGGGGCAGCAAGGGCCTCGGGGCCGAGAGGAGGCGCCCCGCGGGGTCCGCATGGCGGTGCCGCTT CTGCGCAGGATGGAAGGTGCCCCTGCGGGGCCAGGAGGCCGGACAGCCGCCTGCTTCAGTTGTATCCTGTTCTGTTCTGTTCTAGGAGGT TCTGGTGGCGAGGTGGGGGCCGTGAGACGGAGACAACAGGGTCAAGAGGTGGGGGGCAGGGCCAGGAGGTGGGTGAGGGCAGGGCCAGGT GCGGAAGGTGGGGTTTGGGAGATGGGGGTAAGGGGCCGGGTGGGGTGGGGGTGGGGGCTGGGAGTTGGAGGTCGAGGGGTGGCTCAGAGG AAGGGAGTAGGTAGGGGATGGGAGGTGGAGCGTGTGCACAGTTGGGTGCTGGGCGATGGGGTGAGGGGCAGGGGGACAGGAGACAGGGGT TCTTGGGTGTGTGAAGGGATCAGGAGTTGGGGGGAAGCGTGCAAGGTGGGAGCCGGTGGCTGGGGTGTGGGCTGGATGGGGGTGGTGTCA AGCGATGGGGAGAGGTCCCGGCTGATGCGGCAGGGGGCATGGTGGGGAGGGCCTTGGAAGGGCACGCAGGAGTCAGCTTGAGGTGCAACA GAGGAAAGTGGGGAATCAAGACAGCTGGGTGGGGTTGCTGCAGGACCTGGGCCAGTGCGTGGGGAGACAGCCTGAGGGGATGAGATGGGC ACCGGCCAAATCCTAGGAGATGGCACCTTAACTGGGTCCCCACCAGGCACATCACGATGCCTTTCTCGTCGCCCATGGAAGCGGAGCTGG TCCGCAGGATCCTGTCCCGGGATGCCGCACCTCTCCCCCGACCAGGGGCGGTTCTGAAGGACTTCACCGTGTCCGGCAACCTACTGTTTA TGTCAGTTCGGGACCAGGACAGGGAAGGCGCTGGGCGGATGAGGGTGGTGGGTTGGGGGCTGGGATCCGCCTCCCCGGAGGGGCAGAAAG CTAGAGATCTCAGAACACCCAAACACAAGGTCTCAGAACAGAGACCTGGTACACCAGGCCCGCCGCCACCCGAGGGAGCCCAGGGAGATG |
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FusionGenePPI for TTLL10_CTAG2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TTLL10 | FHL3, MDFI, TRIM27, TRIP6, CADPS, PNMA2, RBPMS, THAP1, CEP70, KRT40 | CTAG2 | TRIP6, UBQLN1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TTLL10_CTAG2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TTLL10_CTAG2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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