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Fusion gene ID: 39918 |
FusionGeneSummary for TTC13_JAK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TTC13_JAK2 | Fusion gene ID: 39918 | Hgene | Tgene | Gene symbol | TTC13 | JAK2 | Gene ID | 79573 | 3717 |
| Gene name | tetratricopeptide repeat domain 13 | Janus kinase 2 | |
| Synonyms | - | JTK10|THCYT3 | |
| Cytomap | 1q42.2 | 9p24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tetratricopeptide repeat protein 13TPR repeat protein 13 | tyrosine-protein kinase JAK2JAK-2Janus kinase 2 (a protein tyrosine kinase) | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8NBP0 | O60674 | |
| Ensembl transtripts involved in fusion gene | ENST00000366661, ENST00000366662, ENST00000414259, | ENST00000539801, ENST00000381652, ENST00000544510, ENST00000487310, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 7 X 8 X 4=224 |
| # samples | 2 | 9 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(9/224*10)=-1.31550182572793 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TTC13 [Title/Abstract] AND JAK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | JAK2 | GO:0010811 | positive regulation of cell-substrate adhesion | 10925297 |
| Tgene | JAK2 | GO:0019221 | cytokine-mediated signaling pathway | 8609418 |
| Tgene | JAK2 | GO:0033209 | tumor necrosis factor-mediated signaling pathway | 8609418 |
| Tgene | JAK2 | GO:0034612 | response to tumor necrosis factor | 8609418 |
| Tgene | JAK2 | GO:0035409 | histone H3-Y41 phosphorylation | 19783980 |
| Tgene | JAK2 | GO:0035722 | interleukin-12-mediated signaling pathway | 7528775 |
| Tgene | JAK2 | GO:0046677 | response to antibiotic | 16280321 |
| Tgene | JAK2 | GO:0050727 | regulation of inflammatory response | 10925297 |
| Tgene | JAK2 | GO:0060396 | growth hormone receptor signaling pathway | 10925297 |
| Tgene | JAK2 | GO:0070671 | response to interleukin-12 | 7528775 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-E9-A22D-01A | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000366661 | ENST00000539801 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000366661 | ENST00000381652 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000366661 | ENST00000544510 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| 5CDS-intron | ENST00000366661 | ENST00000487310 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000366662 | ENST00000539801 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000366662 | ENST00000381652 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000366662 | ENST00000544510 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| 5CDS-intron | ENST00000366662 | ENST00000487310 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000414259 | ENST00000539801 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000414259 | ENST00000381652 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| In-frame | ENST00000414259 | ENST00000544510 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
| 5CDS-intron | ENST00000414259 | ENST00000487310 | TTC13 | chr1 | 231075132 | - | JAK2 | chr9 | 5064883 | + |
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FusionProtFeatures for TTC13_JAK2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TTC13 | JAK2 |
| Non-receptor tyrosine kinase involved in variousprocesses such as cell growth, development, differentiation orhistone modifications. Mediates essential signaling events in bothinnate and adaptive immunity. In the cytoplasm, plays a pivotalrole in signal transduction via its association with type Ireceptors such as growth hormone (GHR), prolactin (PRLR), leptin(LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type IIreceptors including IFN-alpha, IFN-beta, IFN-gamma and multipleinterleukins (PubMed:7615558). Following ligand-binding to cellsurface receptors, phosphorylates specific tyrosine residues onthe cytoplasmic tails of the receptor, creating docking sites forSTATs proteins (PubMed:9618263). Subsequently, phosphorylates theSTATs proteins once they are recruited to the receptor.Phosphorylated STATs then form homodimer or heterodimers andtranslocate to the nucleus to activate gene transcription. Forexample, cell stimulation with erythropoietin (EPO) duringerythropoiesis leads to JAK2 autophosphorylation, activation, andits association with erythropoietin receptor (EPOR) that becomesphosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A orSTAT5B) is recruited, phosphorylated and activated by JAK2. Onceactivated, dimerized STAT5 translocates into the nucleus andpromotes the transcription of several essential genes involved inthe modulation of erythropoiesis. Part of a signaling cascade thatis activated by increased cellular retinol and that leads to theactivation of STAT5 (STAT5A or STAT5B) (PubMed:21368206). Inaddition, JAK2 mediates angiotensin-2-induced ARHGEF1phosphorylation (PubMed:20098430). Plays a role in cell cycle byphosphorylating CDKN1B (PubMed:21423214). Cooperates with TECthrough reciprocal phosphorylation to mediate cytokine-drivenactivation of FOS transcription. In the nucleus, plays a key rolein chromatin by specifically mediating phosphorylation of 'Tyr-41'of histone H3 (H3Y41ph), a specific tag that promotes exclusion ofCBX5 (HP1 alpha) from chromatin (PubMed:19783980).{ECO:0000269|PubMed:12023369, ECO:0000269|PubMed:19783980,ECO:0000269|PubMed:20098430, ECO:0000269|PubMed:21368206,ECO:0000269|PubMed:21423214, ECO:0000269|PubMed:7615558,ECO:0000269|PubMed:9618263}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 143_176 | 300 | 861 | Repeat | Note=TPR 1 |
| Hgene | TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 216_248 | 300 | 861 | Repeat | Note=TPR 2 |
| Hgene | TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 249_282 | 300 | 861 | Repeat | Note=TPR 3 |
| Hgene | TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 143_176 | 247 | 807 | Repeat | Note=TPR 1 |
| Hgene | TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 216_248 | 247 | 807 | Repeat | Note=TPR 2 |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 401_482 | 352 | 1133 | Domain | SH2%3B atypical |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 545_809 | 352 | 1133 | Domain | Protein kinase 1 |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 849_1124 | 352 | 1133 | Domain | Protein kinase 2 |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 401_482 | 352 | 1133 | Domain | SH2%3B atypical |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 545_809 | 352 | 1133 | Domain | Protein kinase 1 |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 849_1124 | 352 | 1133 | Domain | Protein kinase 2 |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 855_863 | 352 | 1133 | Nucleotide binding | ATP |
| Tgene | >JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 855_863 | 352 | 1133 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 284_316 | 300 | 861 | Repeat | Note=TPR 4 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 317_350 | 300 | 861 | Repeat | Note=TPR 5 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 352_384 | 300 | 861 | Repeat | Note=TPR 6 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366661 | - | 8 | 23 | 386_418 | 300 | 861 | Repeat | Note=TPR 7 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 249_282 | 247 | 807 | Repeat | Note=TPR 3 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 284_316 | 247 | 807 | Repeat | Note=TPR 4 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 317_350 | 247 | 807 | Repeat | Note=TPR 5 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 352_384 | 247 | 807 | Repeat | Note=TPR 6 |
| Hgene | >TTC13 | chr1:231075132 | chr9:5064883 | ENST00000366662 | - | 6 | 21 | 386_418 | 247 | 807 | Repeat | Note=TPR 7 |
| Tgene | JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 37_380 | 352 | 1133 | Domain | FERM |
| Tgene | JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 37_380 | 352 | 1133 | Domain | FERM |
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FusionGeneSequence for TTC13_JAK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_1081aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_1081aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_1081aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_1028aa MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3243nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTAGTGCAATT TATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAGTAATTACC TTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACT AAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAA GACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAG GAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTAC CTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAA CTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAG CGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGC AGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAG CCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATG AACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGC GTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAG TCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAAT ATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAA GTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATC AGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTT CAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACT TTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTT CCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATA CGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTT TCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGT GTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTA AGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGG CGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAA CTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATA TTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAA CCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTG GTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAG ATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATG ACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGA >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_3243nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTAGTGCAATT TATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAGTAATTACC TTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACT AAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAA GACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAG GAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTAC CTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAA CTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAG CGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGC AGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAG CCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATG AACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGC GTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAG TCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAAT ATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAA GTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATC AGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTT CAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACT TTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTT CCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATA CGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTT TCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGT GTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTA AGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGG CGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAA CTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATA TTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAA CCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTG GTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAG ATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATG ACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGA >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3243nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTAGTGCAATT TATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAGTAATTACC TTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACT AAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAA GACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAG GAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTAC CTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAA CTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAG CGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGC AGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAG CCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATG AACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGC GTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAG TCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAAT ATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAA GTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATC AGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTT CAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACT TTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTT CCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATA CGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTT TCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGT GTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTA AGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGG CGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAA CTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATA TTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAA CCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTG GTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAG ATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATG ACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGA >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3084nt ATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGCTGCTGCTG CTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGGAGCTGCAG CACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCGAGTGCGGC GAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACACTGAGAAG ATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAGCTATTGCT TATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGATTCTGTCCCCTCTGGGACGAATTAAT GAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAG GACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTC TTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTA ACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCG ATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATAT TTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGT GGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTT ACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACA TTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACT TTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAA GCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTA TGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATA AATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGT GCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACA GTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGAC AAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTT TATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGG CCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATG AGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTT GGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAG CATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGA GTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAA GAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGG GATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAA GAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCA GATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATT GGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCA GATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3274nt GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_4643nt GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA TGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATT ACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCT TCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTC TTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGAT GCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGT TCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAAT AAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAAT ATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCT TACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCT AAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACA TTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCA TTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTT ATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGT GTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTC CACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATAC >In-frame_TTC13_ENST00000366661_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3309nt GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3136nt GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_4505nt GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA CAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTG AAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGA TTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGA GACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACC TTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATT ACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAA GCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAA TTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGT GGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGC CAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAG CCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTT GAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCT TGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGT ATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCTTA >In-frame_TTC13_ENST00000366662_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3171nt GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000539801_chr9_5064883_+_3138nt AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000381652_chr9_5064883_+_4507nt AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT TACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATG TGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAG GATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTT GAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATA CCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAA TTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTAT AAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGA AATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTT GTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAAT GCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTA AGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATAT TTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATG CTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAA GTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCT >In-frame_TTC13_ENST00000414259_chr1_231075132_-_JAK2_ENST00000544510_chr9_5064883_+_3173nt AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT |
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FusionGenePPI for TTC13_JAK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TTC13 | FBXO6, TCTN1 | JAK2 | PRMT5, SOCS1, PPIA, IL12RB2, EPOR, FYN, STAT5A, STAT5B, SH2B2, CXCR4, DNAJA3, HSPA8, TEC, PTPN12, PTK2, CSF2RB, GHR, VAV1, SIRPA, IRS1, BRCA1, GRB2, EGFR, PTK2B, PTPN11, TNFRSF1A, SOCS3, PTPN6, LYN, HTR2A, ERBB2, ELP2, KIT, RAF1, SH2B1, IL5RA, PPP2R1B, IFNGR1, IFNGR2, CCR5, PRLR, IL6ST, SHC1, GRB10, TUB, TSHR, STAT3, INSR, STAM, PTPN1, STAM2, IL2RB, CTLA4, ALK, IKBKG, FGFR1, STAT1, HSP90AA1, HSP90AB1, ASB2, SKP2, GTF2I, HIST3H3, HIST2H3C, CDKN1B, VHL, PIK3R1, MAP3K5, AGTR1, PTAFR, JAK2, IL4R, IL2RG, PPP1CC, ERBB3, CALM1, SRC, JAK3, PLCG1, HES1, HES5, ASS1, RBMX, TRAF6, EZH2, DTX3L, EMD, KPNB1, NAP1L1, RCN1, SLC2A1, UBP1, ARL11, HSFY1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | JAK2 | chr1:231075132 | chr9:5064883 | ENST00000381652 | + | 7 | 25 | 1_239 | 352 | 1133 | cytokine/interferon/growth hormone receptors |
| Tgene | JAK2 | chr1:231075132 | chr9:5064883 | ENST00000539801 | + | 6 | 24 | 1_239 | 352 | 1133 | cytokine/interferon/growth hormone receptors |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TTC13_JAK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | JAK2 | O60674 | DB08877 | Ruxolitinib | Tyrosine-protein kinase JAK2 | small molecule | approved |
| Tgene | JAK2 | O60674 | DB08895 | Tofacitinib | Tyrosine-protein kinase JAK2 | small molecule | approved|investigational |
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RelatedDiseases for TTC13_JAK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | JAK2 | C0032463 | Polycythemia Vera | 14 | CTD_human;ORPHANET;UNIPROT |
| Tgene | JAK2 | C0001815 | Primary Myelofibrosis | 9 | CTD_human |
| Tgene | JAK2 | C0040028 | Thrombocythemia, Essential | 8 | CTD_human;ORPHANET |
| Tgene | JAK2 | C0009324 | Ulcerative Colitis | 2 | CTD_human |
| Tgene | JAK2 | C0151744 | Myocardial Ischemia | 2 | CTD_human |
| Tgene | JAK2 | C0836924 | Thrombocytosis | 2 | CTD_human;HPO |
| Tgene | JAK2 | C0856761 | Budd-Chiari Syndrome | 2 | CTD_human;HPO;ORPHANET |
| Tgene | JAK2 | C0000786 | Spontaneous abortion | 1 | CTD_human |
| Tgene | JAK2 | C0006663 | Calcinosis | 1 | CTD_human |
| Tgene | JAK2 | C0018824 | Heart valve disease | 1 | CTD_human |
| Tgene | JAK2 | C0021368 | Inflammation | 1 | CTD_human |
| Tgene | JAK2 | C0023418 | leukemia | 1 | CTD_human |
| Tgene | JAK2 | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human;UNIPROT |
| Tgene | JAK2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | JAK2 | C0025472 | Mesenteric Vascular Occlusion | 1 | CTD_human |
| Tgene | JAK2 | C0027022 | Myeloproliferative disease | 1 | CTD_human;HPO |
| Tgene | JAK2 | C0032461 | Polycythemia | 1 | CTD_human |
| Tgene | JAK2 | C0032962 | Pregnancy Complications | 1 | CTD_human |
| Tgene | JAK2 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Tgene | JAK2 | C0040038 | Thromboembolism | 1 | CTD_human;HPO |
| Tgene | JAK2 | C0042487 | Venous Thrombosis | 1 | CTD_human;HPO |
| Tgene | JAK2 | C3281125 | THROMBOCYTHEMIA 3 | 1 | ORPHANET;UNIPROT |
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