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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 3971

FusionGeneSummary for BCAS3_TLK2

check button Fusion gene summary
Fusion gene informationFusion gene name: BCAS3_TLK2
Fusion gene ID: 3971
HgeneTgene
Gene symbol

BCAS3

TLK2

Gene ID

54828

11011

Gene nameBCAS3, microtubule associated cell migration factortousled like kinase 2
SynonymsGAOB1|MAABHsHPK|PKU-ALPHA
Cytomap

17q23.2

17q23.2

Type of geneprotein-codingprotein-coding
Descriptionbreast carcinoma-amplified sequence 3BCAS4/BCAS3 fusionRudhirabreast carcinoma amplified sequence 4/3 fusion proteinmetastasis associated antigen of breast cancerprotein Maab1serine/threonine-protein kinase tousled-like 2
Modification date2018052320180519
UniProtAcc

Q9H6U6

Q86UE8

Ensembl transtripts involved in fusion geneENST00000589222, ENST00000407086, 
ENST00000390652, ENST00000408905, 
ENST00000588462, ENST00000585744, 
ENST00000588874, ENST00000585812, 
ENST00000582809, ENST00000577616, 
ENST00000326270, ENST00000346027, 
ENST00000343388, ENST00000542523, 
Fusion gene scores* DoF score40 X 23 X 15=138004 X 3 X 2=24
# samples 474
** MAII scorelog2(47/13800*10)=-4.87586369998789
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BCAS3 [Title/Abstract] AND TLK2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Kinase involved fusion gene, inframe and retained kinase domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBCAS3

GO:0043085

positive regulation of catalytic activity

17505058

HgeneBCAS3

GO:0045944

positive regulation of transcription by RNA polymerase II

17505058

HgeneBCAS3

GO:0071391

cellular response to estrogen stimulus

17505058

TgeneTLK2

GO:0001672

regulation of chromatin assembly or disassembly

12660173

TgeneTLK2

GO:0006468

protein phosphorylation

12660173

TgeneTLK2

GO:0006974

cellular response to DNA damage stimulus

12660173

TgeneTLK2

GO:0018105

peptidyl-serine phosphorylation

20016786

TgeneTLK2

GO:0035556

intracellular signal transduction

12660173

TgeneTLK2

GO:0071480

cellular response to gamma radiation

12660173


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDHNSCTCGA-DQ-7589-01ABCAS3chr17

59155890

+TLK2chr17

60673946

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000589222ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000589222ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000589222ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000589222ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000589222ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000589222ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000407086ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000407086ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000407086ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000407086ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000407086ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000407086ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000390652ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000390652ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000390652ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000390652ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000390652ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000390652ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000408905ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000408905ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000408905ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000408905ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000408905ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000408905ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000588462ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588462ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588462ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588462ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588462ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588462ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000585744ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000585744ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000585744ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000585744ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000585744ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000585744ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
In-frameENST00000588874ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588874ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588874ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588874ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588874ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
5CDS-intronENST00000588874ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-3CDSENST00000585812ENST00000582809BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-intronENST00000585812ENST00000577616BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-intronENST00000585812ENST00000326270BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-intronENST00000585812ENST00000346027BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-intronENST00000585812ENST00000343388BCAS3chr17

59155890

+TLK2chr17

60673946

+
intron-intronENST00000585812ENST00000542523BCAS3chr17

59155890

+TLK2chr17

60673946

+

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FusionProtFeatures for BCAS3_TLK2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BCAS3

Q9H6U6

TLK2

Q86UE8

Serine/threonine-protein kinase involved in the processof chromatin assembly and probably also DNA replication,transcription, repair, and chromosome segregation. Phosphorylatesthe chromatin assembly factors ASF1A AND ASF1B. Phosphorylation ofASF1A prevents its proteasome-mediated degradation, therebyenhancing chromatin assembly. Negative regulator of amino acidstarvation-induced autophagy. {ECO:0000269|PubMed:10523312,ECO:0000269|PubMed:11470414, ECO:0000269|PubMed:12660173,ECO:0000269|PubMed:12955071, ECO:0000269|PubMed:20016786,ECO:0000269|PubMed:22354037, ECO:0000269|PubMed:9427565}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTLK2chr17:59155890chr17:60673946ENST00000343388+1421462_741454719DomainProtein kinase
TgeneTLK2chr17:59155890chr17:60673946ENST00000542523+1421462_741454719DomainProtein kinase
TgeneTLK2chr17:59155890chr17:60673946ENST00000343388+1421468_476454719Nucleotide bindingATP
TgeneTLK2chr17:59155890chr17:60673946ENST00000542523+1421468_476454719Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTLK2chr17:59155890chr17:60673946ENST00000326270+1623225_276508773Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000326270+1623317_347508773Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000326270+1623403_451508773Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000343388+1421225_276454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000343388+1421317_347454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000343388+1421403_451454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000346027+1522225_276486751Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000346027+1522317_347486751Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000346027+1522403_451486751Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000542523+1421225_276454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000542523+1421317_347454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000542523+1421403_451454719Coiled coilOntology_term=ECO:0000255
TgeneTLK2chr17:59155890chr17:60673946ENST00000326270+1623462_741508773DomainProtein kinase
TgeneTLK2chr17:59155890chr17:60673946ENST00000346027+1522462_741486751DomainProtein kinase
TgeneTLK2chr17:59155890chr17:60673946ENST00000326270+1623468_476508773Nucleotide bindingATP
TgeneTLK2chr17:59155890chr17:60673946ENST00000346027+1522468_476486751Nucleotide bindingATP


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FusionGeneSequence for BCAS3_TLK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_BCAS3_ENST00000589222_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_1040aa
MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPP
LLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSPPYCCVDLTSLRTGEMVKS
IQFKTPITDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCTPCPGPNMNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVI
SAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFN
TSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPR
VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGT
ITKRTGKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPRPLSTAPKISDDTPLE
MMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPH
RRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVKLTDYFSLDTDSFCTV
LEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMEL
TSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLA

>In-frame_BCAS3_ENST00000407086_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_1040aa
MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPP
LLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSPPYCCVDLTSLRTGEMVKS
IQFKTPITDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCTPCPGPNMNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVI
SAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFN
TSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPR
VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGT
ITKRTGKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPRPLSTAPKISDDTPLE
MMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPH
RRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVKLTDYFSLDTDSFCTV
LEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMEL
TSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLA

>In-frame_BCAS3_ENST00000390652_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_1055aa
MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPP
LLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSPPYCCVDLTSLRTGEMVKS
IQFKTPITDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCTPCPGPNMNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVI
SAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFN
TSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPR
VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGT
ITKRTGPTLFGAGCFSIKAPCKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPR
PLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDE
EWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVK
LTDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSK
IMDDDSYNSVDGMELTSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKP

>In-frame_BCAS3_ENST00000408905_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_1040aa
MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPP
LLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSPPYCCVDLTSLRTGEMVKS
IQFKTPITDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCTPCPGPNMNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVI
SAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFN
TSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPR
VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGT
ITKRTGKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPRPLSTAPKISDDTPLE
MMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPH
RRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVKLTDYFSLDTDSFCTV
LEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMEL
TSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLA

>In-frame_BCAS3_ENST00000588462_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_1055aa
MNEAMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPP
LLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSPPYCCVDLTSLRTGEMVKS
IQFKTPITDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCTPCPGPNMNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVI
SAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFN
TSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPR
VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGT
ITKRTGPTLFGAGCFSIKAPCKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPR
PLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDE
EWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVK
LTDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSK
IMDDDSYNSVDGMELTSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKP

>In-frame_BCAS3_ENST00000585744_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_826aa
MNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVISAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGII
TVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQ
DICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLN
SQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGTITKRTGPTLFGAGCFSIKAPCKVKPPPQISPSKSMGGEFCVAAIFGTSR
SWFANNAGLKREKDQSKQVVVESLYIISCTGTLVEHMMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAA
DAVQTTQFLLAGLVPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHG
PSDTPQPLLDFDTDDLDLNSLRHACREYRIHKELDHPRIVKLTDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNA
LKYLNEIKPPIIHTDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSV
GVIFTQCLTGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGA

>In-frame_BCAS3_ENST00000588874_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_811aa
MNPIALGSRWLATAENKLIRCHQSRGGACGDNIQSTTATVISAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGII
TVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLTTLHRGETEAKVQ
DICFSHDCRWVVVSTLRGTSHVFPINPTGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLN
SQDSTNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAAIFGTSRSWFANNAGLKREKDQ
SKQVVVESLYIISCTGTLVEHMMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQTTQFLLAGLVP
PGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDD
LDLNSLRHACREYRIHKELDHPRIVKLTDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHTD
LKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTTWTLPPECFVVGKEPPKISNKVDVWSVGVIFTQCLTGRKPFG
HNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_BCAS3_ENST00000589222_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3120nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTC
GGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATT
ATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAA
ATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTG
CTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGG
TCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCAT
AGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTG
CAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGG
GAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTA
TTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAG
ATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGT
ACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTA
ACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGAT
GTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAG
AATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCC
TACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGC

>In-frame_BCAS3_ENST00000407086_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3120nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTC
GGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATT
ATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAA
ATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTG
CTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGG
TCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCAT
AGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTG
CAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGG
GAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTA
TTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAG
ATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGT
ACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTA
ACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGAT
GTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAG
AATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCC
TACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGC

>In-frame_BCAS3_ENST00000390652_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3165nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTTTTCCATAAAAGCCCCATGCAAAGTTAAACCTCCTCCACAAATTTCA
CCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGA
GAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGA
CCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCT
CAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCT
GGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAA
GAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCAT
CCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTT
GATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAG
CTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAG
CACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATC
ATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAG
ATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGT
TTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGG
AAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCA
GTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGAT
CCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAAC

>In-frame_BCAS3_ENST00000408905_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3120nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTC
GGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATT
ATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAA
ATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTG
CTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGG
TCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCAT
AGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTG
CAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGG
GAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTA
TTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAG
ATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGT
ACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTA
ACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGAT
GTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAG
AATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCC
TACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGC

>In-frame_BCAS3_ENST00000588462_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3165nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTTTTCCATAAAAGCCCCATGCAAAGTTAAACCTCCTCCACAAATTTCA
CCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGA
GAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGA
CCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCT
CAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCT
GGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAA
GAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCAT
CCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTT
GATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAG
CTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAG
CACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATC
ATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAG
ATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGT
TTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGG
AAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCA
GTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGAT
CCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAAC

>In-frame_BCAS3_ENST00000585744_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_2478nt
ATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGA
GACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAG
CTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATC
ACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCC
CATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTC
CAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAG
GACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGC
CAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAA
GAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAAC
AGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTT
GCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTTTTCCATAAAAGCC
CCATGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGG
TCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTAT
GGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCG
CCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCA
GATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGT
TTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGG
ATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGT
CCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATT
CATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGT
GAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCT
TTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGA
GAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGT
GCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTG
GGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTT
AAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAG
GACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCT

>In-frame_BCAS3_ENST00000588874_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_2433nt
ATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGA
GACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAG
CTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATC
ACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCC
CATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTC
CAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAG
GACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGC
CAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAA
GAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAAC
AGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTT
GCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCG
ATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAG
TCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACT
GCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAA
TTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCC
CCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCC
CAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAA
ACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGAT
CTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTAC
TTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATG
TCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGAC
CTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGAT
GATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGG
AAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGC
CATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCT
GAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTG
CCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAACAGTTCTTCTAAT


* Fusion transcript sequences (Full-length transcript).
>In-frame_BCAS3_ENST00000589222_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_4287nt
CTCGGGGAGACTCCAAACAGTGAGCCTAGAGCTGGAGACTAGCGTTAACCGGCGGGGCGGCCGGTTTTATGAATGAAGCTATGGCTACAG
ATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAGTCCTACATGGAAAGTGTTGTGA
CTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATAGTCTGGGTCAGATTTGAAAATG
CAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCTTTGTTGATTATGATTGGCTACA
GTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACATGGCCCAATTCGAGCGGCTAGAA
TCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGTGTTTGTAAGAGCATTGGATCTT
CTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCCATTCAATTTAAGACACCTATTT
ATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGCTGTACTTTCACGAAGAAATTCT
TTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGA
TTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAA
GTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTA
ATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATT
CTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCA
CAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATA
CTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTA
CTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTT
TCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCA
GCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCT
CTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGCAAAG
TTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTG
CAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAG
TGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCA
GCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTAC
AGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTG
ACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCAC
AGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACA
CGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGC
TGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATG
ATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACT
TAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAA
TTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTT
ATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCT
TCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTG
AAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTG
ATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCAT
CAACCTCTGGGGCGTCCAATAACAGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAACACACACAAAGTGGACAAATGGC
GTTCAGCAGCGGGTTTGGAACATAGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTATTTTCTTGCTTTTTTCCCATCC
ATAGAGCATGACAGCATCGATTCTCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGAAAAGGCCCCGCCCGAGGTTCCA
GCGTCAACGGCCACTGTGTGTGGCTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATGTACTGTGAACTTGAAAACTTGC
AGACTCAGGGGGGTCCCTGATGCAGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCTAGTCCAGTGTCTATATTTAAAC
TTGTTCTTTTCTTTTAATAAAGTTTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTGGGGATGGTGTTTGACTTCGGAG
GAAAAAAGTTGCTATTGCCCGTTAAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTTTAAAAACATGCAGCTTCCCTCT
CCCCTTTTTTATTTTTGAAAGAATACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCAATGTTCATTCCAATCAGATGCA
GCTTTCTCCTCCGTCTGGTCTCCTGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTGGGAGTACTGAGATGTGTGGGTT
TTTGCCATTGGACAAAGAATGAGGTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTTCTTCACAATTTGAACACTTGAC
GGTTGTCCCTTTTAATTTATTTGAAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCTCTTGGATTCTCTGAATGTAGTA
ACTATGAAGCTATGCCAAAGGTAGGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGTTCCTACCCATAGTCTTTGTGTG

>In-frame_BCAS3_ENST00000407086_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_4267nt
TGAGCCTAGAGCTGGAGACTAGCGTTAACCGGCGGGGCGGCCGGTTTTATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGT
CGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAGTCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTG
CCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATAGTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCA
AGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCTTTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGG
AGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACATGGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTT
GGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGTGTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTAC
TGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCCATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAA
CGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGCTGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCA
TGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGT
GGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGG
AAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTG
GTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTG
GCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCAT
GACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACT
GAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATC
AACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTG
GAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTG
CATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATG
GTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATT
TCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAA
AGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCG
CGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACC
CCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTT
GCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGAT
GAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATC
CATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGAT
TTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTT
AAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAA
CAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCC
ATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCG
AAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAG
TGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGA
AGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAG
CCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGT
GATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAAT
AACAGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAACACACACAAAGTGGACAAATGGCGTTCAGCAGCGGGTTTGGAA
CATAGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTATTTTCTTGCTTTTTTCCCATCCATAGAGCATGACAGCATCGA
TTCTCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGAAAAGGCCCCGCCCGAGGTTCCAGCGTCAACGGCCACTGTGTG
TGGCTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATGTACTGTGAACTTGAAAACTTGCAGACTCAGGGGGGTCCCTGA
TGCAGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCTAGTCCAGTGTCTATATTTAAACTTGTTCTTTTCTTTTAATAA
AGTTTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTGGGGATGGTGTTTGACTTCGGAGGAAAAAAGTTGCTATTGCCC
GTTAAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTTTAAAAACATGCAGCTTCCCTCTCCCCTTTTTTATTTTTGAAA
GAATACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCAATGTTCATTCCAATCAGATGCAGCTTTCTCCTCCGTCTGGTC
TCCTGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTGGGAGTACTGAGATGTGTGGGTTTTTGCCATTGGACAAAGAAT
GAGGTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTTCTTCACAATTTGAACACTTGACGGTTGTCCCTTTTAATTTAT
TTGAAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCTCTTGGATTCTCTGAATGTAGTAACTATGAAGCTATGCCAAAG
GTAGGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGTTCCTACCCATAGTCTTTGTGTGCTTGCTAAATGGTGTACATT

>In-frame_BCAS3_ENST00000390652_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_4295nt
ACTAGCGTTAACCGGCGGGGCGGCCGGTTTTATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGT
TGTGGTTCGCCCCCAGGCTGTCACAGAGCAGTCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGG
AACACCTCTAACAGAAGAAAAGGAGAAAATAGTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCA
TGAAATACATAGTACTGGGAATGAACCGCCTTTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGG
TGAAGCACAAGAGCTCTTCTCTGTTCGACATGGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGA
TAACTTTGCTGAAAAAAGACCCCTCCTTGGTGTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTA
TTCACTTCGTACTGGGGAGATGGTCAAGTCCATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGT
CTTGCAGGAGAAAATTGCTGCCTTTGATAGCTGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACAT
GAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGA
CAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCT
GACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCAC
AGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCA
TGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCA
AATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGA
CATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCA
GCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGA
ACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAG
CCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGC
ACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTTTTCCATAAAAGCCCC
ATGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTC
ATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGG
CACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCC
TCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGA
TGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTT
AGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGAT
GGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCC
GAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCA
TAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGA
GGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTT
AAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGA
GATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGC
TGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGG
TGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAA
AGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGA
CCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGC
TATTGCATCAACCTCTGGGGCGTCCAATAACAGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAACACACACAAAGTGGA
CAAATGGCGTTCAGCAGCGGGTTTGGAACATAGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTATTTTCTTGCTTTTT
TCCCATCCATAGAGCATGACAGCATCGATTCTCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGAAAAGGCCCCGCCCG
AGGTTCCAGCGTCAACGGCCACTGTGTGTGGCTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATGTACTGTGAACTTGA
AAACTTGCAGACTCAGGGGGGTCCCTGATGCAGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCTAGTCCAGTGTCTAT
ATTTAAACTTGTTCTTTTCTTTTAATAAAGTTTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTGGGGATGGTGTTTGA
CTTCGGAGGAAAAAAGTTGCTATTGCCCGTTAAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTTTAAAAACATGCAGC
TTCCCTCTCCCCTTTTTTATTTTTGAAAGAATACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCAATGTTCATTCCAAT
CAGATGCAGCTTTCTCCTCCGTCTGGTCTCCTGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTGGGAGTACTGAGATG
TGTGGGTTTTTGCCATTGGACAAAGAATGAGGTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTTCTTCACAATTTGAA
CACTTGACGGTTGTCCCTTTTAATTTATTTGAAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCTCTTGGATTCTCTGA
ATGTAGTAACTATGAAGCTATGCCAAAGGTAGGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGTTCCTACCCATAGTC

>In-frame_BCAS3_ENST00000408905_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_4219nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTC
GGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATT
ATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAA
ATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTG
CTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGG
TCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCAT
AGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTG
CAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGG
GAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTA
TTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAG
ATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGT
ACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTA
ACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGAT
GTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAG
AATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCC
TACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGC
CCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAACAGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAAC
ACACACAAAGTGGACAAATGGCGTTCAGCAGCGGGTTTGGAACATAGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTA
TTTTCTTGCTTTTTTCCCATCCATAGAGCATGACAGCATCGATTCTCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGA
AAAGGCCCCGCCCGAGGTTCCAGCGTCAACGGCCACTGTGTGTGGCTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATG
TACTGTGAACTTGAAAACTTGCAGACTCAGGGGGGTCCCTGATGCAGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCT
AGTCCAGTGTCTATATTTAAACTTGTTCTTTTCTTTTAATAAAGTTTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTG
GGGATGGTGTTTGACTTCGGAGGAAAAAAGTTGCTATTGCCCGTTAAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTT
TAAAAACATGCAGCTTCCCTCTCCCCTTTTTTATTTTTGAAAGAATACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCA
ATGTTCATTCCAATCAGATGCAGCTTTCTCCTCCGTCTGGTCTCCTGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTG
GGAGTACTGAGATGTGTGGGTTTTTGCCATTGGACAAAGAATGAGGTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTT
CTTCACAATTTGAACACTTGACGGTTGTCCCTTTTAATTTATTTGAAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCT
CTTGGATTCTCTGAATGTAGTAACTATGAAGCTATGCCAAAGGTAGGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGT

>In-frame_BCAS3_ENST00000588462_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_4264nt
ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCTGTCACAGAGCAG
TCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGGAATGAACCGCCT
TTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATCCCTATCAGTGGTGAAGCACAAGAGCTCTTCTCTGTTCGACAT
GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGACCCCTCCTTGGT
GTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCTGCCTTTGATAGC
TGTACTTTCACGAAGAAATTCTTTGTTACAAGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATT
AGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGC
CAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAA
TGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGA
GTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAAC
AACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
ATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTTTTCCATAAAAGCCCCATGCAAAGTTAAACCTCCTCCACAAATTTCA
CCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGA
GAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGA
CCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCT
CAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCT
GGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAA
GAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCAT
CCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTT
GATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAG
CTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAG
CACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATC
ATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAG
ATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGT
TTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGG
AAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCA
GTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGAT
CCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAAC
AGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAACACACACAAAGTGGACAAATGGCGTTCAGCAGCGGGTTTGGAACAT
AGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTATTTTCTTGCTTTTTTCCCATCCATAGAGCATGACAGCATCGATTC
TCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGAAAAGGCCCCGCCCGAGGTTCCAGCGTCAACGGCCACTGTGTGTGG
CTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATGTACTGTGAACTTGAAAACTTGCAGACTCAGGGGGGTCCCTGATGC
AGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCTAGTCCAGTGTCTATATTTAAACTTGTTCTTTTCTTTTAATAAAGT
TTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTGGGGATGGTGTTTGACTTCGGAGGAAAAAAGTTGCTATTGCCCGTT
AAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTTTAAAAACATGCAGCTTCCCTCTCCCCTTTTTTATTTTTGAAAGAA
TACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCAATGTTCATTCCAATCAGATGCAGCTTTCTCCTCCGTCTGGTCTCC
TGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTGGGAGTACTGAGATGTGTGGGTTTTTGCCATTGGACAAAGAATGAG
GTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTTCTTCACAATTTGAACACTTGACGGTTGTCCCTTTTAATTTATTTG
AAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCTCTTGGATTCTCTGAATGTAGTAACTATGAAGCTATGCCAAAGGTA
GGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGTTCCTACCCATAGTCTTTGTGTGCTTGCTAAATGGTGTACATTTCT

>In-frame_BCAS3_ENST00000585744_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3680nt
GCCGCCTTGCAGTTTGATCTCAGACTGCTGTGCTGGCAATCAGCGAGACTCCGTGGGCGTAGGACCCTCCGAGCCAGGCTGCTATCCATG
TCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGG
TGGAGCCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAA
AGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGT
CCCAGGCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGC
CCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGA
CTTTCATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGA
AGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAA
CCCTTATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGA
AGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCA
TGGGAAACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGT
AGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGGCCTTATCTCTTTGGAGCGGGGTGTTT
TTCCATAAAAGCCCCATGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTT
CGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACAT
TATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGA
AATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCT
GCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGG
GTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCA
TAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTT
GCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAG
GGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGT
ATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCA
GATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGG
TACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCT
AACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGA
TGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGCCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGA
GAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGC
CTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCTACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAG
CCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAACAGTTCTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAA
CACACACAAAGTGGACAAATGGCGTTCAGCAGCGGGTTTGGAACATAGCGAATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTT
ATTTTCTTGCTTTTTTCCCATCCATAGAGCATGACAGCATCGATTCTCATTGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGG
AAAAGGCCCCGCCCGAGGTTCCAGCGTCAACGGCCACTGTGTGTGGCTGCTCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCAT
GTACTGTGAACTTGAAAACTTGCAGACTCAGGGGGGTCCCTGATGCAGTGCTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGC
TAGTCCAGTGTCTATATTTAAACTTGTTCTTTTCTTTTAATAAAGTTTAGGTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCT
GGGGATGGTGTTTGACTTCGGAGGAAAAAAGTTGCTATTGCCCGTTAAAGGCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTT
TTAAAAACATGCAGCTTCCCTCTCCCCTTTTTTATTTTTGAAAGAATACATTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGC
AATGTTCATTCCAATCAGATGCAGCTTTCTCCTCCGTCTGGTCTCCTGTTTGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGT
GGGAGTACTGAGATGTGTGGGTTTTTGCCATTGGACAAAGAATGAGGTTAGAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATT
TCTTCACAATTTGAACACTTGACGGTTGTCCCTTTTAATTTATTTGAAGTGCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCC
TCTTGGATTCTCTGAATGTAGTAACTATGAAGCTATGCCAAAGGTAGGCAGAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAG

>In-frame_BCAS3_ENST00000588874_chr17_59155890_+_TLK2_ENST00000582809_chr17_60673946_+_3720nt
GCCGCCTTGCAGTTTGATCTCAGACTGCTGTGCTGGCAATCAGCGAGACTCCGTGGGCGTAGGACCCTCCGAGCCAGGTGTGGGATATAG
TCTCGTGGTGCGCCGTTTTTTAAGCCGGTCTGAAAAGCGCAATATTCGGGTGGGAGTGACCCGATTTTCCAGGCTGCTATCCATGTCCAG
GGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTTGCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAG
CCTGTGGAGACAACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTGACAATGGTAGGGAAAGTGG
TGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAAGATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAG
GCATCATCACAGTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGTGATGGCATTGTGGCCCACT
TCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAATACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTC
ATGTCTTCCAAATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCACAGGGGAGAAACTGAAGCCA
AAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTTGTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTT
ATGGTGGCCAGCCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGACTGGAAGAGA
TTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGCCCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGA
AACTGAACAGCCAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTTCCCAGCTTGATGGTAGTGA
TGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACCATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCA
GCAAATCGATGGGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAATGCAGGTCTGAAAAGAGAAA
AAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATTATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCC
TCAGCACTGCACCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACTCTGGTTAGAACCCCTCAAT
GGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTGCTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCC
TGGTTCCCCCTGGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGTGGACAGGAAGATGAAGAAT
GGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCATAGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCT
CAGGCCAAACCACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAGCCTCTTTTGGATTTTGATA
CAGATGATCTTGATCTCAACAGTCTCAGGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGT
ATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACA
AATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATAC
ACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCA
TGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTATTTACCACCAGAGTGTTTTG
TGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAGC
CTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAG
TAACACCTGAAGCAAAGGCGTTTATTCGACGATGCTTGGCCTACCGAAAGGAGGACCGCATTGATGTCCAGCAGCTGGCCTGTGATCCCT
ACTTGTTGCCTCACATCCGAAAGTCAGTCTCTACAAGTAGCCCTGCTGGAGCTGCTATTGCATCAACCTCTGGGGCGTCCAATAACAGTT
CTTCTAATTGAGACTGACTCCAAGGCCACAAACTGTTCAACACACACAAAGTGGACAAATGGCGTTCAGCAGCGGGTTTGGAACATAGCG
AATCCGAATGGATCTGATGAAACCTGTACCAGGTGCTTTTATTTTCTTGCTTTTTTCCCATCCATAGAGCATGACAGCATCGATTCTCAT
TGAGGAGAAACCTTGGGCAGCTCCGGCCAGGCCTTGTAGGAAAAGGCCCCGCCCGAGGTTCCAGCGTCAACGGCCACTGTGTGTGGCTGC
TCTGAGTGAGGAAAAAATTAAAAAGAAAAACTGGTTCCATGTACTGTGAACTTGAAAACTTGCAGACTCAGGGGGGTCCCTGATGCAGTG
CTTCAGATGAAGAATGTGGACTTGAAAATACAGACTGGGCTAGTCCAGTGTCTATATTTAAACTTGTTCTTTTCTTTTAATAAAGTTTAG
GTAACATCTCCTGAAAAGCTTGTAGCACAAAGGCTCAGCTGGGGATGGTGTTTGACTTCGGAGGAAAAAAGTTGCTATTGCCCGTTAAAG
GCACTAGAGTTAGTGTTTTATCCCTAAATAATTTCAATTTTTAAAAACATGCAGCTTCCCTCTCCCCTTTTTTATTTTTGAAAGAATACA
TTTGGTCATAAAGTGAAACCCGTATTAGCAAGTACGTGGCAATGTTCATTCCAATCAGATGCAGCTTTCTCCTCCGTCTGGTCTCCTGTT
TGCAATTGCTTCCCTCATCTCAGTAGGGAAAAAATTGAGTGGGAGTACTGAGATGTGTGGGTTTTTGCCATTGGACAAAGAATGAGGTTA
GAAGACTGCAGCTTGGAGTCTCTCTAGGTTTTCAACTATTTCTTCACAATTTGAACACTTGACGGTTGTCCCTTTTAATTTATTTGAAGT
GCTATTTTTTTAAATAAAGGTTCATCTGTCCATGCAGTCCTCTTGGATTCTCTGAATGTAGTAACTATGAAGCTATGCCAAAGGTAGGCA
GAAAATGGGCTTGGGAGCCAGACACTCCAGGGATCAGTAGTTCCTACCCATAGTCTTTGTGTGCTTGCTAAATGGTGTACATTTCTTGTT


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FusionGenePPI for BCAS3_TLK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
BCAS3CTBP1, CTBP2, CDC23, C16orf70, ZDHHC17, ESR1, PELP1, HIST1H3A, KAT2B, WIPI2, ATM, BAG4, CCND1, FBXW7, KRAS, PALB2, PHB, PTPN1, SMAD4, STK11, TGFB1, TSG101, XRCC3, OFD1, CEP128, FBF1, NPHP1, SCLT1, XPO1, CD14, HDAC1, IRF3, MAGEE1, IL17RA, DOCK5, VWA5A, RAB2BTLK2ASF1B, ASF1A, TLK1, FEZ1, FEZ2, AURKA, IRF4, IRF7, ELAVL1, XPO7, XPO1, RPS6KA1, RFPL3, EID3, LHX6, STK24, NTRK1, DYNLL1, NFATC2, SPATA1, RPS27A, CABIN1, IL36A, DYNLL2, AMOTL1, IFFO1, CDADC1, SCML1, COBLL1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for BCAS3_TLK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for BCAS3_TLK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource