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Fusion gene ID: 39623 |
FusionGeneSummary for TRIT1_ADH1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TRIT1_ADH1B | Fusion gene ID: 39623 | Hgene | Tgene | Gene symbol | TRIT1 | ADH1B | Gene ID | 54802 | 125 |
| Gene name | tRNA isopentenyltransferase 1 | alcohol dehydrogenase 1B (class I), beta polypeptide | |
| Synonyms | COXPD35|GRO1|IPPT|IPT|IPTase|MOD5|hGRO1 | ADH2|HEL-S-117 | |
| Cytomap | 1p34.2 | 4q23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tRNA dimethylallyltransferaseIPP transferaseisopentenyl-diphosphate:tRNA isopentenyltransferasetRNA dimethylallyltransferase, mitochondrialtRNA isopentenylpyrophosphate transferase | alcohol dehydrogenase 1BADH, beta subunitalcohol dehydrogenase 2 (class I), beta polypeptidealcohol dehydrogenase subunit betaaldehyde reductaseepididymis secretory protein Li 117 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9H3H1 | P00325 | |
| Ensembl transtripts involved in fusion gene | ENST00000441669, ENST00000316891, ENST00000372818, ENST00000491865, ENST00000541099, ENST00000537440, ENST00000537223, ENST00000545233, ENST00000544981, | ENST00000305046, ENST00000394887, ENST00000504498, | |
| Fusion gene scores | * DoF score | 5 X 1 X 3=15 | 1 X 1 X 1=1 |
| # samples | 3 | 1 | |
| ** MAII score | log2(3/15*10)=1 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: TRIT1 [Title/Abstract] AND ADH1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ADH1B | GO:0006069 | ethanol oxidation | 2398055 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LIHC | TCGA-PD-A5DF-01A | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000441669 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000441669 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000441669 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| In-frame | ENST00000316891 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000316891 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000316891 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| In-frame | ENST00000372818 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000372818 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000372818 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-3CDS | ENST00000491865 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000491865 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000491865 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-3CDS | ENST00000541099 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000541099 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000541099 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-3CDS | ENST00000537440 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000537440 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000537440 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-3CDS | ENST00000537223 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000537223 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000537223 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-3CDS | ENST00000545233 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000545233 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5UTR-5UTR | ENST00000545233 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| In-frame | ENST00000544981 | ENST00000305046 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000544981 | ENST00000394887 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
| 5CDS-5UTR | ENST00000544981 | ENST00000504498 | TRIT1 | chr1 | 40348990 | - | ADH1B | chr4 | 100240043 | - |
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FusionProtFeatures for TRIT1_ADH1B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TRIT1 | ADH1B |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 32_37 | 58 | 468 | Region | Substrate binding |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 32_37 | 58 | 442 | Region | Substrate binding |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 32_37 | 58 | 386 | Region | Substrate binding |
| Tgene | >ADH1B | chr1:40348990 | chr4:100240043 | ENST00000305046 | - | 0 | 9 | 200_205 | 6 | 376 | Nucleotide binding | Note=NAD |
| Tgene | >ADH1B | chr1:40348990 | chr4:100240043 | ENST00000305046 | - | 0 | 9 | 293_295 | 6 | 376 | Nucleotide binding | Note=NAD |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 395_425 | 58 | 468 | Zinc finger | Note=Matrin-type |
| Hgene | >TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 395_425 | 58 | 442 | Zinc finger | Note=Matrin-type |
| Hgene | >TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 395_425 | 58 | 386 | Zinc finger | Note=Matrin-type |
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FusionGeneSequence for TRIT1_ADH1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_428aa MASVAAARAVPVGSGLRGLQRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVR IKMVAVGICHTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML >In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_428aa MASVAAARAVPVGSGLRGLQRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVR IKMVAVGICHTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML >In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_428aa MASVAAARAVPVGSGLRGLQRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVR IKMVAVGICHTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML >In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_428aa MASVAAARAVPVGSGLRGLQRTLPLVVILGATGTGKSTLALQLGQRLGGEIVSADSMQVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVR IKMVAVGICHTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGT RRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_1284nt ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC AAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGCTTATGAAGTTCGC ATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT GAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT GGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC AGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGATGAGAATGCAGTG GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGCAGTTAACGTTGCC AAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC AGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAATAAACCCTATGCTG CTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGCTGATTTTATGGCT AAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCACTCTGGGAAAAGT >In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_1284nt ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC AAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGCTTATGAAGTTCGC ATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT GAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT GGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC AGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGATGAGAATGCAGTG GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGCAGTTAACGTTGCC AAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC AGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAATAAACCCTATGCTG CTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGCTGATTTTATGGCT AAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCACTCTGGGAAAAGT >In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_1284nt ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC AAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGCTTATGAAGTTCGC ATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT GAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT GGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC AGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGATGAGAATGCAGTG GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGCAGTTAACGTTGCC AAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC AGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAATAAACCCTATGCTG CTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGCTGATTTTATGGCT AAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCACTCTGGGAAAAGT >In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_1284nt ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC AAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGCTTATGAAGTTCGC ATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT GAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT GGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC AGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGATGAGAATGCAGTG GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGCAGTTAACGTTGCC AAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC AGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAATAAACCCTATGCTG CTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGCTGATTTTATGGCT AAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCACTCTGGGAAAAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_4160nt ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTAATC AAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGCTTATGAAGTTCGC ATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCAT GAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGTGT GGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCTGCAGGATGGCACC AGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGATGAGAATGCAGTG GCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGCAGTTAACGTTGCC AAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGCAGCTGGAGCAGCC AGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAG AAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCT TCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAATAAACCCTATGCTG CTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGCTGATTTTATGGCT AAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCACTCTGGGAAAAGT ATCCGTACCGTCCTGACGTTTTGAGGCAATAGAGATGCCTTCCCCTGTAGCAGTCTTCAGCCTCCTCTACCCTACAAGATCTGGAGCAAC AGCTAGGAAATATCATTAATTCAGCTCTTCAGAGATGTTATCAATAAATTACACATGGGGGCTTTCCAAAGAAATGGAAATTGATGGGAA ATTATTTTTCAGGAAAATTTAAAATTCAAGTGAGAAGTAAATAAAGTGTTGAACATCAGCTGGGGAATTGAAGCCAACAAACCTTCCTTC TTAACCATTCTACTGTGTCACCTTTGCCATTGAGGAAAAATATTCCTGTGACTTCTTGCATTTTTGGTATCTTCATAATCTTTAGTCATC GAATCCCAGTGGAGGGGACCCTTTTACTTGCCCTGAACATACACATGCTGGGCCATTGTGATTGAAGTCTTCTAACTCTGTCTCAGTTTT CACTGTCGACATTTTCCTTTTTCTAATAAAAATGTACCAAATCCCTGGGGTAAAAGCTAGGGTAAGGTAAAGGATAGACTCACATTTACA AGTAGTGAAGGTCCAAGAGTTCTAAATACAGGAAATTTCTTAGGAACTCAAATAAAATGCCCCACATTTTACTACAGTAAATGGCAGTGT TTTTATGACTTTTATACTATTTCTTTATGGTCGATATACAATTGATTTTTTAAAATAATAGCAGATTTCTTGCTTCATATGACAAAGCCT CAATTACTAATTGTAAAAACTGAACTATTCCCAGAATCATGTTCAAAAAATCTGTAATTTTTGCTGATGAAAGTGCTTCATTGACTAAAC AGTATTAGTTTGTGGCTATAAATGATTATTTAGATGATGACTGAAAATGTGTATAAAGTAATTAAAAGTAATATGGTGGCTTTAAGTGTA GAGATGGGATGGCAAATGCTGTGAATGCAGAATGTAAAATTGGTAACTAAGAAATGGCACAAACACCTTAAGCAATATATTTTCCTAGTA GATATATATATACACATACATATATACACATATACAAATGTATATTTTTGCAAAATTGTTTTCAATCTAGAACTTTTCTATTAACTACCA TGTCTTAAAATCAAGTCTATAATCCTAGCATTAGTTTAATATTTTGAATATGTAAAGACCTGTGTTAATGCTTTGTTAATGCTTTTCCCA CTCTCATTTGTTAATGCTTTCCCACTCTCAGGGGAAGGATTTGCATTTTGAGCTTTATCTCTAAATGTGACATGCAAAGATTATTCCTGG TAAAGGAGGTAGCTGTCTCCAAAAATGCTATTGTTGCAATATCTACATTCTATTTCATATTATGAAAGACCTTAGACATAAAGTAAAATA GTTTATCATTTACTGTGTGATCTTCAGTAAGTCTCTCAGGCTCTCTGAGCTTGTTCATCCTTTGTTTTGAAAAAATTACTCAACCAATCC ATTACAGCTTAACCAAGATTAAATGGGATGATGTTAATGAAAGAGCTTCGCCAATTAAGAAGGGCCATGTAAATGTGGGTAACCTGATTG TTTTGTCAAAAATGCTAAAGCGGGGTGGGGGGTGGCGCAGTGGCTTATCCCTGTAATCCCAGCACTTTGGGAGGTCAAGACGGGTGGATG ACCTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTTGCCAGGCATGGTGGCA GGTGGCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATCGCTGGAGCCTGGGAGGCGGAGGTTGCAGTGAGCAGAAATCTTGCC ACTGCACAGCAGCCTAGGCGACAAGAGCAAAACTCTGTCAAAAGAAAAGAAAAGAAAATGCTGAAGGAGTTACTCAGGGTCAAGAAAGTT TTCAGAATGTCCGTAAGATAACATCATCATGGGACACTACCTGTTGCTGGGTGCTCTGCGGCTTTTACACTGATGCTGATTGTGTGAGAT CCAGAAAAAGAAAATGGAGTTCTACATGCCCATCTCACAGCAGGGTCATCAAATCCTGCTAGTGACACAGAAGCTGACATCCAGCTCCCA CCCGCCTTCCTCCCAGGTTCGGGGAGCAGGTAGAGTGGGAGCCATTAGGTGGGCTCTGCCAGTGTTGTCATAGAGTGGCAAGTCCTCCAT GGGATGGGAGTGGCATGTGGGAGCCTTCTGCATCATGCACTATGAAAAAAGAAAATTTACTATGGGGCAAGTGGTTCATATAGTTAAGTG ATTGTATATATATATATATATATATATATATATATATATATATATATATATACACTATGGGGCAAGTGGTTCATATAGTTAAGTGATTGT ATATATATATATATATATATATGTATTCCAGTGTAGAAAGTATTGGCTGGGTCTGTAATCAAGTATTCCACAGAAGTGCCTTCATAGGTG CTGAAACAGGATTATGAGAGTGACAGACACAGGACTGAAGACAGGGAGAAAATGTGCATGGCTGTGAGAATATATTGCTTTGATTCTTTG ACTTCTCATGATATATGAAAACAAATAAAGTGGGGGGGGGTGACTTCAATAATATCACGAACATATTTAAAATGAAATTCTGAGCATGGA GAAAAATTTCAAATTCTGGTATAAACAAATAATCTAAAAATATAGATAAGGAAAAAATGTTTTCATTTTTTTGGTCATATTGATTTGGGT CATATATGATTGACCAAAAAAAAAGATATTTCTAAAATCCTGGTGCTTTTTCATTTAAAAATAGACAACCAAAGAGGAAAATGAACAATG ATGGAAATTCGTGGAAGAGGAAACTAAAATGGCAAAATAGCATATTAAATGGCACTGAGCCTTGGTGTGATCAAAAAAAAAAATAAAGCA >In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_4175nt GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC TCCATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAG GCTTATGAAGTTCGCATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCT GTGATTTTAGGCCATGAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTC TTTACTCCTCAGTGTGGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACC CTGCAGGATGGCACCAGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTG GATGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCT GCAGTTAACGTTGCCAAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAA GCAGCTGGAGCAGCCAGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAAC CCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTT GACACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCA ATAAACCCTATGCTGCTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTG GCTGATTTTATGGCTAAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTT CACTCTGGGAAAAGTATCCGTACCGTCCTGACGTTTTGAGGCAATAGAGATGCCTTCCCCTGTAGCAGTCTTCAGCCTCCTCTACCCTAC AAGATCTGGAGCAACAGCTAGGAAATATCATTAATTCAGCTCTTCAGAGATGTTATCAATAAATTACACATGGGGGCTTTCCAAAGAAAT GGAAATTGATGGGAAATTATTTTTCAGGAAAATTTAAAATTCAAGTGAGAAGTAAATAAAGTGTTGAACATCAGCTGGGGAATTGAAGCC AACAAACCTTCCTTCTTAACCATTCTACTGTGTCACCTTTGCCATTGAGGAAAAATATTCCTGTGACTTCTTGCATTTTTGGTATCTTCA TAATCTTTAGTCATCGAATCCCAGTGGAGGGGACCCTTTTACTTGCCCTGAACATACACATGCTGGGCCATTGTGATTGAAGTCTTCTAA CTCTGTCTCAGTTTTCACTGTCGACATTTTCCTTTTTCTAATAAAAATGTACCAAATCCCTGGGGTAAAAGCTAGGGTAAGGTAAAGGAT AGACTCACATTTACAAGTAGTGAAGGTCCAAGAGTTCTAAATACAGGAAATTTCTTAGGAACTCAAATAAAATGCCCCACATTTTACTAC AGTAAATGGCAGTGTTTTTATGACTTTTATACTATTTCTTTATGGTCGATATACAATTGATTTTTTAAAATAATAGCAGATTTCTTGCTT CATATGACAAAGCCTCAATTACTAATTGTAAAAACTGAACTATTCCCAGAATCATGTTCAAAAAATCTGTAATTTTTGCTGATGAAAGTG CTTCATTGACTAAACAGTATTAGTTTGTGGCTATAAATGATTATTTAGATGATGACTGAAAATGTGTATAAAGTAATTAAAAGTAATATG GTGGCTTTAAGTGTAGAGATGGGATGGCAAATGCTGTGAATGCAGAATGTAAAATTGGTAACTAAGAAATGGCACAAACACCTTAAGCAA TATATTTTCCTAGTAGATATATATATACACATACATATATACACATATACAAATGTATATTTTTGCAAAATTGTTTTCAATCTAGAACTT TTCTATTAACTACCATGTCTTAAAATCAAGTCTATAATCCTAGCATTAGTTTAATATTTTGAATATGTAAAGACCTGTGTTAATGCTTTG TTAATGCTTTTCCCACTCTCATTTGTTAATGCTTTCCCACTCTCAGGGGAAGGATTTGCATTTTGAGCTTTATCTCTAAATGTGACATGC AAAGATTATTCCTGGTAAAGGAGGTAGCTGTCTCCAAAAATGCTATTGTTGCAATATCTACATTCTATTTCATATTATGAAAGACCTTAG ACATAAAGTAAAATAGTTTATCATTTACTGTGTGATCTTCAGTAAGTCTCTCAGGCTCTCTGAGCTTGTTCATCCTTTGTTTTGAAAAAA TTACTCAACCAATCCATTACAGCTTAACCAAGATTAAATGGGATGATGTTAATGAAAGAGCTTCGCCAATTAAGAAGGGCCATGTAAATG TGGGTAACCTGATTGTTTTGTCAAAAATGCTAAAGCGGGGTGGGGGGTGGCGCAGTGGCTTATCCCTGTAATCCCAGCACTTTGGGAGGT CAAGACGGGTGGATGACCTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTTG CCAGGCATGGTGGCAGGTGGCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATCGCTGGAGCCTGGGAGGCGGAGGTTGCAGTG AGCAGAAATCTTGCCACTGCACAGCAGCCTAGGCGACAAGAGCAAAACTCTGTCAAAAGAAAAGAAAAGAAAATGCTGAAGGAGTTACTC AGGGTCAAGAAAGTTTTCAGAATGTCCGTAAGATAACATCATCATGGGACACTACCTGTTGCTGGGTGCTCTGCGGCTTTTACACTGATG CTGATTGTGTGAGATCCAGAAAAAGAAAATGGAGTTCTACATGCCCATCTCACAGCAGGGTCATCAAATCCTGCTAGTGACACAGAAGCT GACATCCAGCTCCCACCCGCCTTCCTCCCAGGTTCGGGGAGCAGGTAGAGTGGGAGCCATTAGGTGGGCTCTGCCAGTGTTGTCATAGAG TGGCAAGTCCTCCATGGGATGGGAGTGGCATGTGGGAGCCTTCTGCATCATGCACTATGAAAAAAGAAAATTTACTATGGGGCAAGTGGT TCATATAGTTAAGTGATTGTATATATATATATATATATATATATATATATATATATATATATATATACACTATGGGGCAAGTGGTTCATA TAGTTAAGTGATTGTATATATATATATATATATATATGTATTCCAGTGTAGAAAGTATTGGCTGGGTCTGTAATCAAGTATTCCACAGAA GTGCCTTCATAGGTGCTGAAACAGGATTATGAGAGTGACAGACACAGGACTGAAGACAGGGAGAAAATGTGCATGGCTGTGAGAATATAT TGCTTTGATTCTTTGACTTCTCATGATATATGAAAACAAATAAAGTGGGGGGGGGTGACTTCAATAATATCACGAACATATTTAAAATGA AATTCTGAGCATGGAGAAAAATTTCAAATTCTGGTATAAACAAATAATCTAAAAATATAGATAAGGAAAAAATGTTTTCATTTTTTTGGT CATATTGATTTGGGTCATATATGATTGACCAAAAAAAAAGATATTTCTAAAATCCTGGTGCTTTTTCATTTAAAAATAGACAACCAAAGA GGAAAATGAACAATGATGGAAATTCGTGGAAGAGGAAACTAAAATGGCAAAATAGCATATTAAATGGCACTGAGCCTTGGTGTGATCAAA >In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_4175nt GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC TCCATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAG GCTTATGAAGTTCGCATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCT GTGATTTTAGGCCATGAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTC TTTACTCCTCAGTGTGGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACC CTGCAGGATGGCACCAGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTG GATGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCT GCAGTTAACGTTGCCAAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAA GCAGCTGGAGCAGCCAGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAAC CCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTT GACACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCA ATAAACCCTATGCTGCTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTG GCTGATTTTATGGCTAAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTT CACTCTGGGAAAAGTATCCGTACCGTCCTGACGTTTTGAGGCAATAGAGATGCCTTCCCCTGTAGCAGTCTTCAGCCTCCTCTACCCTAC AAGATCTGGAGCAACAGCTAGGAAATATCATTAATTCAGCTCTTCAGAGATGTTATCAATAAATTACACATGGGGGCTTTCCAAAGAAAT GGAAATTGATGGGAAATTATTTTTCAGGAAAATTTAAAATTCAAGTGAGAAGTAAATAAAGTGTTGAACATCAGCTGGGGAATTGAAGCC AACAAACCTTCCTTCTTAACCATTCTACTGTGTCACCTTTGCCATTGAGGAAAAATATTCCTGTGACTTCTTGCATTTTTGGTATCTTCA TAATCTTTAGTCATCGAATCCCAGTGGAGGGGACCCTTTTACTTGCCCTGAACATACACATGCTGGGCCATTGTGATTGAAGTCTTCTAA CTCTGTCTCAGTTTTCACTGTCGACATTTTCCTTTTTCTAATAAAAATGTACCAAATCCCTGGGGTAAAAGCTAGGGTAAGGTAAAGGAT AGACTCACATTTACAAGTAGTGAAGGTCCAAGAGTTCTAAATACAGGAAATTTCTTAGGAACTCAAATAAAATGCCCCACATTTTACTAC AGTAAATGGCAGTGTTTTTATGACTTTTATACTATTTCTTTATGGTCGATATACAATTGATTTTTTAAAATAATAGCAGATTTCTTGCTT CATATGACAAAGCCTCAATTACTAATTGTAAAAACTGAACTATTCCCAGAATCATGTTCAAAAAATCTGTAATTTTTGCTGATGAAAGTG CTTCATTGACTAAACAGTATTAGTTTGTGGCTATAAATGATTATTTAGATGATGACTGAAAATGTGTATAAAGTAATTAAAAGTAATATG GTGGCTTTAAGTGTAGAGATGGGATGGCAAATGCTGTGAATGCAGAATGTAAAATTGGTAACTAAGAAATGGCACAAACACCTTAAGCAA TATATTTTCCTAGTAGATATATATATACACATACATATATACACATATACAAATGTATATTTTTGCAAAATTGTTTTCAATCTAGAACTT TTCTATTAACTACCATGTCTTAAAATCAAGTCTATAATCCTAGCATTAGTTTAATATTTTGAATATGTAAAGACCTGTGTTAATGCTTTG TTAATGCTTTTCCCACTCTCATTTGTTAATGCTTTCCCACTCTCAGGGGAAGGATTTGCATTTTGAGCTTTATCTCTAAATGTGACATGC AAAGATTATTCCTGGTAAAGGAGGTAGCTGTCTCCAAAAATGCTATTGTTGCAATATCTACATTCTATTTCATATTATGAAAGACCTTAG ACATAAAGTAAAATAGTTTATCATTTACTGTGTGATCTTCAGTAAGTCTCTCAGGCTCTCTGAGCTTGTTCATCCTTTGTTTTGAAAAAA TTACTCAACCAATCCATTACAGCTTAACCAAGATTAAATGGGATGATGTTAATGAAAGAGCTTCGCCAATTAAGAAGGGCCATGTAAATG TGGGTAACCTGATTGTTTTGTCAAAAATGCTAAAGCGGGGTGGGGGGTGGCGCAGTGGCTTATCCCTGTAATCCCAGCACTTTGGGAGGT CAAGACGGGTGGATGACCTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTTG CCAGGCATGGTGGCAGGTGGCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATCGCTGGAGCCTGGGAGGCGGAGGTTGCAGTG AGCAGAAATCTTGCCACTGCACAGCAGCCTAGGCGACAAGAGCAAAACTCTGTCAAAAGAAAAGAAAAGAAAATGCTGAAGGAGTTACTC AGGGTCAAGAAAGTTTTCAGAATGTCCGTAAGATAACATCATCATGGGACACTACCTGTTGCTGGGTGCTCTGCGGCTTTTACACTGATG CTGATTGTGTGAGATCCAGAAAAAGAAAATGGAGTTCTACATGCCCATCTCACAGCAGGGTCATCAAATCCTGCTAGTGACACAGAAGCT GACATCCAGCTCCCACCCGCCTTCCTCCCAGGTTCGGGGAGCAGGTAGAGTGGGAGCCATTAGGTGGGCTCTGCCAGTGTTGTCATAGAG TGGCAAGTCCTCCATGGGATGGGAGTGGCATGTGGGAGCCTTCTGCATCATGCACTATGAAAAAAGAAAATTTACTATGGGGCAAGTGGT TCATATAGTTAAGTGATTGTATATATATATATATATATATATATATATATATATATATATATATATACACTATGGGGCAAGTGGTTCATA TAGTTAAGTGATTGTATATATATATATATATATATATGTATTCCAGTGTAGAAAGTATTGGCTGGGTCTGTAATCAAGTATTCCACAGAA GTGCCTTCATAGGTGCTGAAACAGGATTATGAGAGTGACAGACACAGGACTGAAGACAGGGAGAAAATGTGCATGGCTGTGAGAATATAT TGCTTTGATTCTTTGACTTCTCATGATATATGAAAACAAATAAAGTGGGGGGGGGTGACTTCAATAATATCACGAACATATTTAAAATGA AATTCTGAGCATGGAGAAAAATTTCAAATTCTGGTATAAACAAATAATCTAAAAATATAGATAAGGAAAAAATGTTTTCATTTTTTTGGT CATATTGATTTGGGTCATATATGATTGACCAAAAAAAAAGATATTTCTAAAATCCTGGTGCTTTTTCATTTAAAAATAGACAACCAAAGA GGAAAATGAACAATGATGGAAATTCGTGGAAGAGGAAACTAAAATGGCAAAATAGCATATTAAATGGCACTGAGCCTTGGTGTGATCAAA >In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ADH1B_ENST00000305046_chr4_100240043_-_4173nt AGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGT AGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTC CATGCAGGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGGTAAAGAAACCCTTTTCCATTGAGGATGTGGAGGTTGCACCTCCTAAGGC TTATGAAGTTCGCATTAAGATGGTGGCTGTAGGAATCTGTCACACAGATGACCACGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGT GATTTTAGGCCATGAGGCAGCCGGCATCGTGGAGAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTT TACTCCTCAGTGTGGAAAATGCAGAGTTTGTAAAAACCCGGAGAGCAACTACTGCTTGAAAAATGATCTAGGCAATCCTCGGGGGACCCT GCAGGATGGCACCAGGAGGTTCACCTGCAGGGGGAAGCCCATTCACCACTTCCTTGGCACCAGCACCTTCTCCCAGTACACGGTGGTGGA TGAGAATGCAGTGGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTCTCGACTGGTTATGGGTCTGC AGTTAACGTTGCCAAGGTCACCCCAGGCTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGCTGTTATGGGCTGTAAAGC AGCTGGAGCAGCCAGAATCATTGCGGTGGACATCAACAAGGACAAATTTGCAAAGGCCAAAGAGTTGGGTGCCACTGAATGCATCAACCC TCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGAAATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGA CACCATGATGGCTTCCCTGTTATGTTGTCATGAGGCATGTGGCACAAGCGTCATCGTAGGGGTACCTCCTGCTTCCCAGAACCTCTCAAT AAACCCTATGCTGCTACTGACTGGACGCACCTGGAAGGGGGCTGTTTATGGTGGCTTTAAGAGTAAAGAAGGTATCCCAAAACTTGTGGC TGATTTTATGGCTAAGAAGTTTTCACTGGATGCGTTAATAACCCATGTTTTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCA CTCTGGGAAAAGTATCCGTACCGTCCTGACGTTTTGAGGCAATAGAGATGCCTTCCCCTGTAGCAGTCTTCAGCCTCCTCTACCCTACAA GATCTGGAGCAACAGCTAGGAAATATCATTAATTCAGCTCTTCAGAGATGTTATCAATAAATTACACATGGGGGCTTTCCAAAGAAATGG AAATTGATGGGAAATTATTTTTCAGGAAAATTTAAAATTCAAGTGAGAAGTAAATAAAGTGTTGAACATCAGCTGGGGAATTGAAGCCAA CAAACCTTCCTTCTTAACCATTCTACTGTGTCACCTTTGCCATTGAGGAAAAATATTCCTGTGACTTCTTGCATTTTTGGTATCTTCATA ATCTTTAGTCATCGAATCCCAGTGGAGGGGACCCTTTTACTTGCCCTGAACATACACATGCTGGGCCATTGTGATTGAAGTCTTCTAACT CTGTCTCAGTTTTCACTGTCGACATTTTCCTTTTTCTAATAAAAATGTACCAAATCCCTGGGGTAAAAGCTAGGGTAAGGTAAAGGATAG ACTCACATTTACAAGTAGTGAAGGTCCAAGAGTTCTAAATACAGGAAATTTCTTAGGAACTCAAATAAAATGCCCCACATTTTACTACAG TAAATGGCAGTGTTTTTATGACTTTTATACTATTTCTTTATGGTCGATATACAATTGATTTTTTAAAATAATAGCAGATTTCTTGCTTCA TATGACAAAGCCTCAATTACTAATTGTAAAAACTGAACTATTCCCAGAATCATGTTCAAAAAATCTGTAATTTTTGCTGATGAAAGTGCT TCATTGACTAAACAGTATTAGTTTGTGGCTATAAATGATTATTTAGATGATGACTGAAAATGTGTATAAAGTAATTAAAAGTAATATGGT GGCTTTAAGTGTAGAGATGGGATGGCAAATGCTGTGAATGCAGAATGTAAAATTGGTAACTAAGAAATGGCACAAACACCTTAAGCAATA TATTTTCCTAGTAGATATATATATACACATACATATATACACATATACAAATGTATATTTTTGCAAAATTGTTTTCAATCTAGAACTTTT CTATTAACTACCATGTCTTAAAATCAAGTCTATAATCCTAGCATTAGTTTAATATTTTGAATATGTAAAGACCTGTGTTAATGCTTTGTT AATGCTTTTCCCACTCTCATTTGTTAATGCTTTCCCACTCTCAGGGGAAGGATTTGCATTTTGAGCTTTATCTCTAAATGTGACATGCAA AGATTATTCCTGGTAAAGGAGGTAGCTGTCTCCAAAAATGCTATTGTTGCAATATCTACATTCTATTTCATATTATGAAAGACCTTAGAC ATAAAGTAAAATAGTTTATCATTTACTGTGTGATCTTCAGTAAGTCTCTCAGGCTCTCTGAGCTTGTTCATCCTTTGTTTTGAAAAAATT ACTCAACCAATCCATTACAGCTTAACCAAGATTAAATGGGATGATGTTAATGAAAGAGCTTCGCCAATTAAGAAGGGCCATGTAAATGTG GGTAACCTGATTGTTTTGTCAAAAATGCTAAAGCGGGGTGGGGGGTGGCGCAGTGGCTTATCCCTGTAATCCCAGCACTTTGGGAGGTCA AGACGGGTGGATGACCTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTTGCC AGGCATGGTGGCAGGTGGCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATCGCTGGAGCCTGGGAGGCGGAGGTTGCAGTGAG CAGAAATCTTGCCACTGCACAGCAGCCTAGGCGACAAGAGCAAAACTCTGTCAAAAGAAAAGAAAAGAAAATGCTGAAGGAGTTACTCAG GGTCAAGAAAGTTTTCAGAATGTCCGTAAGATAACATCATCATGGGACACTACCTGTTGCTGGGTGCTCTGCGGCTTTTACACTGATGCT GATTGTGTGAGATCCAGAAAAAGAAAATGGAGTTCTACATGCCCATCTCACAGCAGGGTCATCAAATCCTGCTAGTGACACAGAAGCTGA CATCCAGCTCCCACCCGCCTTCCTCCCAGGTTCGGGGAGCAGGTAGAGTGGGAGCCATTAGGTGGGCTCTGCCAGTGTTGTCATAGAGTG GCAAGTCCTCCATGGGATGGGAGTGGCATGTGGGAGCCTTCTGCATCATGCACTATGAAAAAAGAAAATTTACTATGGGGCAAGTGGTTC ATATAGTTAAGTGATTGTATATATATATATATATATATATATATATATATATATATATATATATACACTATGGGGCAAGTGGTTCATATA GTTAAGTGATTGTATATATATATATATATATATATGTATTCCAGTGTAGAAAGTATTGGCTGGGTCTGTAATCAAGTATTCCACAGAAGT GCCTTCATAGGTGCTGAAACAGGATTATGAGAGTGACAGACACAGGACTGAAGACAGGGAGAAAATGTGCATGGCTGTGAGAATATATTG CTTTGATTCTTTGACTTCTCATGATATATGAAAACAAATAAAGTGGGGGGGGGTGACTTCAATAATATCACGAACATATTTAAAATGAAA TTCTGAGCATGGAGAAAAATTTCAAATTCTGGTATAAACAAATAATCTAAAAATATAGATAAGGAAAAAATGTTTTCATTTTTTTGGTCA TATTGATTTGGGTCATATATGATTGACCAAAAAAAAAGATATTTCTAAAATCCTGGTGCTTTTTCATTTAAAAATAGACAACCAAAGAGG AAAATGAACAATGATGGAAATTCGTGGAAGAGGAAACTAAAATGGCAAAATAGCATATTAAATGGCACTGAGCCTTGGTGTGATCAAAAA |
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FusionGenePPI for TRIT1_ADH1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TRIT1 | HGH1, SMYD3, SHE, ANKS1A | ADH1B | YWHAE, PDE4DIP, GNB2L1, SERPINA3, PML, IRAK3, ADH1C |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 55_58 | 58 | 468 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 55_58 | 58 | 442 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 55_58 | 58 | 386 | substrate tRNA |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 233_255 | 58 | 468 | isopentenylpyrophosphate transferase |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 233_255 | 58 | 442 | isopentenylpyrophosphate transferase |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 233_255 | 58 | 386 | isopentenylpyrophosphate transferase |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 183_187 | 58 | 468 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 281_283 | 58 | 468 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 313_331 | 58 | 468 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000316891 | - | 1 | 11 | 323_330 | 58 | 468 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 183_187 | 58 | 442 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 281_283 | 58 | 442 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 313_331 | 58 | 442 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000372818 | - | 1 | 10 | 323_330 | 58 | 442 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 183_187 | 58 | 386 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 281_283 | 58 | 386 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 313_331 | 58 | 386 | substrate tRNA |
| Hgene | TRIT1 | chr1:40348990 | chr4:100240043 | ENST00000441669 | - | 1 | 9 | 323_330 | 58 | 386 | substrate tRNA |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TRIT1_ADH1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | ADH1B | P00325 | DB09462 | Glycerin | Alcohol dehydrogenase 1B | small molecule | approved|investigational |
| Tgene | ADH1B | P00325 | DB01213 | Fomepizole | Alcohol dehydrogenase 1B | small molecule | approved|vet_approved |
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RelatedDiseases for TRIT1_ADH1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | TRIT1 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Tgene | ADH1B | C0001973 | Alcoholic Intoxication, Chronic | 8 | CTD_human;PSYGENET |
| Tgene | ADH1B | C0001969 | Alcoholic Intoxication | 5 | PSYGENET |
| Tgene | ADH1B | C0085762 | Alcohol abuse | 5 | PSYGENET |
| Tgene | ADH1B | C0007785 | Cerebral Infarction | 1 | CTD_human |
| Tgene | ADH1B | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| Tgene | ADH1B | C0014859 | Esophageal Neoplasms | 1 | CTD_human |
| Tgene | ADH1B | C0023055 | Laryngeal neoplasm | 1 | CTD_human |
| Tgene | ADH1B | C0026640 | Mouth Neoplasms | 1 | CTD_human |
| Tgene | ADH1B | C0028754 | Obesity | 1 | CTD_human |
| Tgene | ADH1B | C0031347 | Pharyngeal Neoplasms | 1 | CTD_human |
| Tgene | ADH1B | C0033975 | Psychotic Disorders | 1 | PSYGENET |
| Tgene | ADH1B | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Tgene | ADH1B | C0349464 | Wernicke-Korsakoff Syndrome | 1 | PSYGENET |
| Tgene | ADH1B | C0393756 | Hangover from alcohol | 1 | PSYGENET |
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